PUBLICATIONS
The LIFE Child-study covers a lot of different research topics. For further reading, find the publication list below. Topic-specific listings include the publications‘ abstracts
Follow us on X for more information on publications and other science topics related to LIFE Child.
Scientific Publications
The list is ordered by date. The latest publication is on top.
2390247
T52N9QLZ
1
chicago-fullnote-bibliography
50
date
desc
1
6748
https://home.uni-leipzig.de/lifechild/wp-content/plugins/zotpress/
%7B%22status%22%3A%22success%22%2C%22updateneeded%22%3Afalse%2C%22instance%22%3Afalse%2C%22meta%22%3A%7B%22request_last%22%3A200%2C%22request_next%22%3A50%2C%22used_cache%22%3Atrue%7D%2C%22data%22%3A%5B%7B%22key%22%3A%22YYBRDW2S%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Holvoet%20et%20al.%22%2C%22parsedDate%22%3A%222024-12-31%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EHolvoet%2C%20S%26%23xE9%3Bbastien%2C%20Francis%20Foata%2C%20Sophie%20Nutten%2C%20Ellen%20N%26%23xED%3B%20Cl%26%23xE9%3Birigh%2C%20Maya%20Shevlyakova%2C%20Cheong%20Kwong%20Chung%2C%20Gregory%20Lefevre%2C%20et%20al.%20%26%23x201C%3BImpact%20of%20Consumption%20of%20the%20Human%20Milk%20Oligosaccharides%202%26%23×2032%3B-FL%20and%20LNnT%20on%20Reduction%20of%20Risk%20of%20Allergic%20Sensitisation.%26%23x201D%3B%20%3Ci%3EFood%20and%20Agricultural%20Immunology%3C%5C%2Fi%3E%2035%2C%20no.%201%20%28December%2031%2C%202024%29%3A%202301703.%20%3Ca%20class%3D%27zp-ItemURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1080%5C%2F09540105.2023.2301703%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1080%5C%2F09540105.2023.2301703%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Impact%20of%20consumption%20of%20the%20human%20milk%20oligosaccharides%202%5Cu2032-FL%20and%20LNnT%20on%20reduction%20of%20risk%20of%20allergic%20sensitisation%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22S%5Cu00e9bastien%22%2C%22lastName%22%3A%22Holvoet%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Francis%22%2C%22lastName%22%3A%22Foata%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Sophie%22%2C%22lastName%22%3A%22Nutten%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ellen%22%2C%22lastName%22%3A%22N%5Cu00ed%20Cl%5Cu00e9irigh%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Maya%22%2C%22lastName%22%3A%22Shevlyakova%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Cheong%22%2C%22lastName%22%3A%22Kwong%20Chung%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Gregory%22%2C%22lastName%22%3A%22Lefevre%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Norbert%22%2C%22lastName%22%3A%22Sprenger%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tristan%22%2C%22lastName%22%3A%22Bourdeau%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Dominique%22%2C%22lastName%22%3A%22Donnicola%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mario%22%2C%22lastName%22%3A%22Noti%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Severine%22%2C%22lastName%22%3A%22Combremont%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Aristea%22%2C%22lastName%22%3A%22Binia%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Chiara%22%2C%22lastName%22%3A%22Nembrini%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Carine%22%2C%22lastName%22%3A%22Blanchard%22%7D%5D%2C%22abstractNote%22%3A%22Human%20Milk%20Oligosaccharides%20%28HMOs%29%20have%20been%20proposed%20to%20be%20instrumental%20in%20building%20immune%20competence.%20To%20explore%20the%20role%20of%20HMOs%20in%20allergy%20prevention%2C%20twenty-one%20HMOs%20were%20quantified%20in%20breast%20milk%20samples%20and%20associated%20with%20sensitisation%20in%20infants.%202%5Cu2032-fucosyllactose%20%282%5Cu2032-FL%29%20levels%20were%20positively%20associated%20with%20an%20increased%20risk%20of%20sensitisation%2C%20atopic%20dermatitis%20and%20recurrent%20skin%20rash.%20Interestingly%2C%202%5Cu2032-FL%20levels%2C%20ranging%20from%201.35%20to%201.95%20g%5C%2FL%2C%20were%20associated%20with%20a%20higher%20prevalence%20of%20non-allergic%20and%20non-sensitised%20infants.%20The%20role%20of%202%5Cu2032-FL%20and%20lacto-N-neotetraose%20%28LNnT%29%20was%20further%20investigated%20in%20allergic%20sensitisation%20models%20in%20vivo.%20Oral%20administration%20of%20HMOs%20decreased%20allergic%20sensitisation.%20This%20was%20associated%20with%20gut%20microbiota%20and%20short-chain%20fatty%20acid%20%28SCFA%29%20production%20changes.%20Aligned%20with%20the%20clinical%20associations%2C%20the%20decreased%20sensitisation%20was%20not%20observed%20with%20lower%20and%20higher%20tested%20doses%20of%20the%20HMOs%20supporting%20a%20U-shape%20association%20between%202%5Cu2032-FL%20and%20LNnT%20levels%20and%20allergic%20sensitisation%20risk%20reduction%20in%20humans%20and%20mice.%20Trial%20registration%3A%20ClinicalTrials.gov%20identifier%3A%20NCT02550236.%22%2C%22date%22%3A%222024-12-31%22%2C%22language%22%3A%22%22%2C%22DOI%22%3A%2210.1080%5C%2F09540105.2023.2301703%22%2C%22ISSN%22%3A%220954-0105%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1080%5C%2F09540105.2023.2301703%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222024-08-27T12%3A04%3A19Z%22%7D%7D%2C%7B%22key%22%3A%22NX7CWJYQ%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Jensch%20et%20al.%22%2C%22parsedDate%22%3A%222024-09%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EJensch%2C%20Ricky%2C%20Ronny%20Baber%2C%20Antje%20K%26%23xF6%3Brner%2C%20Wieland%20Kiess%2C%20Uta%20Ceglarek%2C%20Antje%20Garten%2C%20and%20Mandy%20Vogel.%20%26%23x201C%3BAssociation%20of%20Whole%20Blood%20Amino%20Acid%20and%20Acylcarnitine%20Metabolome%20with%20Anthropometry%20and%20IGF-I%20Serum%20Levels%20in%20Healthy%20Children%20and%20Adolescents%20in%20Germany.%26%23x201D%3B%20%3Ci%3EMetabolites%3C%5C%2Fi%3E%2014%2C%20no.%209%20%28September%202024%29%3A%20489.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Fmetabo14090489%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Fmetabo14090489%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Association%20of%20Whole%20Blood%20Amino%20Acid%20and%20Acylcarnitine%20Metabolome%20with%20Anthropometry%20and%20IGF-I%20Serum%20Levels%20in%20Healthy%20Children%20and%20Adolescents%20in%20Germany%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ricky%22%2C%22lastName%22%3A%22Jensch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ronny%22%2C%22lastName%22%3A%22Baber%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Uta%22%2C%22lastName%22%3A%22Ceglarek%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22Garten%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%5D%2C%22abstractNote%22%3A%22Background%3A%20Physiological%20changes%20of%20blood%20amino%20acids%20and%20acylcarnitines%20during%20healthy%20child%20development%20are%20poorly%20studied.%20The%20LIFE%20%28Leipziger%20Forschungszentrum%20f%5Cu00fcr%20Zivilisationserkrankungen%29%20Child%20study%20offers%20a%20platform%20with%20a%20large%20cohort%20of%20healthy%20children%20to%20investigate%20these%20dynamics.%20We%20aimed%20to%20assess%20the%20intra-person%20variability%20of%2028%20blood%20metabolites%20and%20their%20associations%20with%20anthropometric%20parameters%20related%20to%20growth%20and%20excess%20body%20fat.%20Methods%3A%20Concentrations%20of%2022%20amino%20acids%20%28AA%29%2C%205%20acylcarnitines%20%28AC%29%20and%20free%20carnitine%20of%202213%20children%20aged%20between%203%20months%20and%2019%20years%20were%20analyzed%20using%20liquid%20chromatography%5C%2Ftandem%20mass%20spectrometry.%20Values%20were%20transformed%20into%20standard%20deviation%20scores%20%28SDS%29%20to%20account%20for%20sex-%20and%20age-related%20variations.%20The%20stability%20of%20metabolites%20was%20assessed%20through%20the%20coefficient%20of%20determination.%20Associations%20with%20parameters%20for%20body%20composition%20and%20insulin-like%20growth%20factor-I%20%28IGF-I%29%20SDS%20were%20determined%20by%20the%20Pearson%20correlation%20and%20linear%20regression.%20Results%3A%20Our%20research%20revealed%20substantial%20within-person%20variation%20in%20metabolite%20concentrations%20during%20childhood%20and%20adolescence.%20Most%20metabolites%20showed%20a%20positive%20correlation%20with%20body%20composition%20parameters%2C%20with%20a%20notable%20influence%20of%20sex%2C%20pubertal%20status%20and%20weight%20group.%20Glycine%20exhibited%20negative%20associations%20with%20parameters%20of%20body%20fat%20distribution%2C%20especially%20in%20normal%20weight%20girls%2C%20overweight%5C%2Fobese%20boys%20and%20during%20puberty.%20Conclusion%3A%20Blood%20AA%20and%20AC%20measurements%20may%20contribute%20to%20elucidating%20pathogenesis%20pathways%20of%20adiposity-related%20comorbidities%2C%20but%20the%20specific%20timings%20and%20conditions%20of%20development%20during%20childhood%20and%20adolescence%20need%20to%20be%20taken%20into%20consideration.%22%2C%22date%22%3A%222024%5C%2F9%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.3390%5C%2Fmetabo14090489%22%2C%22ISSN%22%3A%222218-1989%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.mdpi.com%5C%2F2218-1989%5C%2F14%5C%2F9%5C%2F489%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222024-09-11T07%3A10%3A18Z%22%7D%7D%2C%7B%22key%22%3A%22SHIYK6W6%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22lastModifiedByUser%22%3A%7B%22id%22%3A5423163%2C%22username%22%3A%22erossi19%22%2C%22name%22%3A%22%22%2C%22links%22%3A%7B%22alternate%22%3A%7B%22href%22%3A%22https%3A%5C%2F%5C%2Fwww.zotero.org%5C%2Ferossi19%22%2C%22type%22%3A%22text%5C%2Fhtml%22%7D%7D%7D%2C%22creatorSummary%22%3A%22Wagner%20et%20al.%22%2C%22parsedDate%22%3A%222024-07-22%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EWagner%2C%20Friederike%2C%20Robert%20Zeidler%2C%20Uta%20Ceglarek%2C%20Wieland%20Kiess%2C%20J%26%23xFC%3Brgen%20Kratzsch%2C%20Alexander%20Gaudl%2C%20Ronald%20Biemann%2C%20and%20Mandy%20Vogel.%20%26%23x201C%3BObesity%20Is%20Associated%20with%20Increased%2011-Oxyandrogen%20Serum%20Concentrations%20during%20Puberty.%26%23x201D%3B%20%3Ci%3EHormone%20Research%20in%20Paediatrics%3C%5C%2Fi%3E%2C%20July%2022%2C%202024.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1159%5C%2F000540433%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1159%5C%2F000540433%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Obesity%20is%20associated%20with%20increased%2011-oxyandrogen%20serum%20concentrations%20during%20puberty%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Friederike%22%2C%22lastName%22%3A%22Wagner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Robert%22%2C%22lastName%22%3A%22Zeidler%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Uta%22%2C%22lastName%22%3A%22Ceglarek%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J%5Cu00fcrgen%22%2C%22lastName%22%3A%22Kratzsch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Alexander%22%2C%22lastName%22%3A%22Gaudl%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ronald%22%2C%22lastName%22%3A%22Biemann%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%5D%2C%22abstractNote%22%3A%22Introduction%3A%20While%20the%20influence%20of%20various%20factors%20on%20classical%20androgen%20synthesis%20in%20children%20and%20adolescents%20and%20its%20impact%20on%20puberty%20has%20been%20widely%20investigated%2C%20there%20appear%20to%20be%20gaps%20and%20contradictory%20findings%20regarding%20the%20association%20of%20overweight%20and%20obesity%20with%20the%20synthesis%20of%20adrenal-derived%2011-oxygenated%20androgen%20%2811-OA%29%20serum%20levels.%20With%20this%20study%2C%20we%20aimed%20to%20examine%20how%20overweight%20and%20obesity%20affect%2011-OA%20serum%20levels%20during%20puberty%20in%20a%20large%20cohort%20of%20children%20and%20adolescents.%5CnMethods%3A%20Our%20cohort%20comprised%201%2C054%20healthy%20children%20aged%206%20to%2019%20years%20providing%20serum%20samples%20at%20a%20total%20of%201%2C734%20visits.%20Liquid%20chromatography-tandem%20mass%20spectrometry%20was%20used%20to%20quantify%2011-ketotestosterone%20%2811KT%29%2C%2011-ketoandrostendione%20%2811-KA4%29%2C%2011-%5Cu00df-hydroxytestosterone%20%2811-OHT%29%2C%2011-%5Cu00df-hydroxyandrostendione%20%2811OHA4%29%2C%20testosterone%2C%20androstenedione%2C%20and%20DHEAS.%20In%20addition%2C%20we%20assessed%20BMI-SDSs%3B%20skinfold%20thicknesses%3B%20and%20Tanner%20stages.%20The%20significance%20level%20%5Cu03b1%20was%20set%20to%20%5Cu03b1%3D0.05.%5CnResults%3A%20Increases%20in%2011-KT%2C%2011-KA4%2C%2011-OHT%2C%20and%2011-OHA4%20levels%20were%20observed%20in%20boys%20and%20girls%20during%20puberty.%2011-KT%20%28%5Cu00df%3D0.2%2C%20p%3C0.001%29%2C%2011-KA4%20%28%5Cu00df%3D0.16%2C%20p%3C0.001%29%20and%2011-OHA4%20%28%5Cu00df%3D0.12%2C%20p%3D0.003%29%20were%20positively%20correlated%20with%20BMI%20in%20boys%20age%2013%20and%20under.%2011-KT%20%28%5Cu00df%3D0.1%2C%20p%3D0.047%29%20was%20positively%20correlated%20with%20BMI%20in%20girls%20age%2011%20and%20under.%2011-OHT%20was%20positively%20correlated%20with%20BMI%20independent%20of%20age%20%28boys%2013%20and%20under%3A%20%5Cu00df%3D0.17%2C%20p%3C0.001%3B%20over%2013%20years%3A%20%5Cu00df%3D0.14%2C%20p%3D0.001%3B%20girls%2011%20and%20under%3A%20%5Cu00df%3D0.17%2C%20p%3C0.001%3B%20over%2011%20years%3A%20%5Cu00df%3D0.18%2C%20p%3C0.001%29.%5CnConclusion%3A%20We%20found%20increasing%2011-OA%20serum%20levels%20throughout%20all%20Tanner%20stages.%2011-OAs%20were%20observed%20to%20be%20associated%20with%20BMI%20and%20skinfold%20thickness%2C%20suggesting%20that%20overweight%20and%20obesity%20may%20be%20associated%20with%20pubertal%20alterations%20in%2011-OA%20serum%20levels.%22%2C%22date%22%3A%222024-7-22%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1159%5C%2F000540433%22%2C%22ISSN%22%3A%221663-2818%2C%201663-2826%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fkarger.com%5C%2Fdoi%5C%2F10.1159%5C%2F000540433%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222024-08-27T12%3A20%3A40Z%22%7D%7D%2C%7B%22key%22%3A%22YYGNEXF2%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22lastModifiedByUser%22%3A%7B%22id%22%3A5423163%2C%22username%22%3A%22erossi19%22%2C%22name%22%3A%22%22%2C%22links%22%3A%7B%22alternate%22%3A%7B%22href%22%3A%22https%3A%5C%2F%5C%2Fwww.zotero.org%5C%2Ferossi19%22%2C%22type%22%3A%22text%5C%2Fhtml%22%7D%7D%7D%2C%22creatorSummary%22%3A%22Grosse-Thie%20et%20al.%22%2C%22parsedDate%22%3A%222024-07-19%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EGrosse-Thie%2C%20Charlotte%2C%20Mandy%20Vogel%2C%20Ronny%20Baber%2C%20Uta%20Ceglarek%2C%20and%20Wieland%20Kiess.%20%26%23x201C%3BBilirubin%20Levels%20in%20Infancy%20and%20Their%20Associations%20with%20Body%20Weight%2C%20Levels%20of%20Iron-Related%20Parameters%20and%20Steroid%20Hormone%20Levels.%26%23x201D%3B%20%3Ci%3EMetabolites%3C%5C%2Fi%3E%2014%2C%20no.%207%20%28July%2019%2C%202024%29%3A%20393.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Fmetabo14070393%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Fmetabo14070393%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Bilirubin%20Levels%20in%20Infancy%20and%20Their%20Associations%20with%20Body%20Weight%2C%20Levels%20of%20Iron-Related%20Parameters%20and%20Steroid%20Hormone%20Levels%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Charlotte%22%2C%22lastName%22%3A%22Grosse-Thie%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ronny%22%2C%22lastName%22%3A%22Baber%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Uta%22%2C%22lastName%22%3A%22Ceglarek%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%5D%2C%22abstractNote%22%3A%22It%20is%20assumed%20that%20bilirubin%20is%20hormonally%20regulated%20and%20influences%20weight%20development%20by%20preventing%20weight%20gain.%20However%2C%20studies%20in%20healthy%20infants%20are%20limited.%20The%20present%20study%20established%20reference%20values%20for%20bilirubin%20and%20investigated%20whether%20bilirubin%20levels%20are%20significantly%20associated%20with%20body%20weight%2C%20levels%20of%20ferritin%20and%20transferrin%20as%20well%20as%20steroid%20hormone%20levels%20in%20a%20study%20population%20of%20three-%20and%20six-month-old%20healthy%20infants.%20Data%20from%20a%20total%20of%20411%20study%20visits%20from%20the%20LIFE%20Child%20study%20%28Leipzig%2C%20Germany%29%20were%20analyzed.%20Associations%20were%20examined%20using%20linear%20regression%20analyses.%20Besides%20laboratory%20parameters%2C%20anthropometric%20data%20were%20gathered.%20We%20found%20statistically%20significant%20associations%20between%20body%20weight%20and%20bilirubin%20levels.%20In%20girls%2C%20we%20observed%20additional%20associations%20between%20bilirubin%20levels%20and%20both%20ferritin%20and%20transferrin%20concentrations%20at%20three%20months%20of%20age.%20At%20six%20months%2C%20steroid%20hormone%20levels%20were%20significantly%20associated%20with%20concentrations%20of%20total%20and%20indirect%20bilirubin%2C%20with%20effects%20differing%20by%20sex.%20Our%20study%20thus%20confirms%20associations%20already%20reported%20from%20animal%20studies%20and%20studies%20in%20adult%20populations.%20Furthermore%2C%20we%20showed%20that%20these%20associations%20already%20exist%20in%20the%20first%20year%20of%20life%2C%20are%20influenced%20by%20sex%20and%20age%20and%2C%20further%2C%20depend%20on%20the%20bilirubin%20type.%20Our%20results%20provide%20reference%20values%20for%20bilirubin%20and%20assist%2C%20therefore%2C%20in%20interpreting%20bilirubin%20levels%20in%20infancy.%22%2C%22date%22%3A%222024-07-19%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.3390%5C%2Fmetabo14070393%22%2C%22ISSN%22%3A%222218-1989%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.mdpi.com%5C%2F2218-1989%5C%2F14%5C%2F7%5C%2F393%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222024-08-27T12%3A22%3A08Z%22%7D%7D%2C%7B%22key%22%3A%22BT9XFL8H%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Poulain%20et%20al.%22%2C%22parsedDate%22%3A%222024-07-12%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EPoulain%2C%20Tanja%2C%20Cornelia%20Hilbert%2C%20Annelie%20Grundmann%2C%20and%20Wieland%20Kiess.%20%26%23x201C%3BAssociations%20between%20Media%20Use%20at%20Bedtime%20and%20Sleep%3A%20A%20Cross-Sectional%20Analysis%20on%20Differences%20between%20Girls%20and%20Boys.%26%23x201D%3B%20%3Ci%3EFrontiers%20in%20Psychology%3C%5C%2Fi%3E%2015%20%28July%2012%2C%202024%29.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3389%5C%2Ffpsyg.2024.1290935%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3389%5C%2Ffpsyg.2024.1290935%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Associations%20between%20media%20use%20at%20bedtime%20and%20sleep%3A%20a%20cross-sectional%20analysis%20on%20differences%20between%20girls%20and%20boys%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Cornelia%22%2C%22lastName%22%3A%22Hilbert%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Annelie%22%2C%22lastName%22%3A%22Grundmann%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%5D%2C%22abstractNote%22%3A%22%3Csec%20id%3D%5C%22sec1%5C%22%3E%3Ctitle%3EObjectives%3C%5C%2Ftitle%3E%3Cp%3EThis%20study%20investigated%20associations%20between%20the%20use%20of%20electronic%20media%20and%20sleep%20in%20children%20and%20young%20adolescents%2C%20with%20a%20specific%20focus%20on%20the%20moderation%20of%20associations%20by%20sex%20and%20age.%3C%5C%2Fp%3E%3C%5C%2Fsec%3E%3Csec%20id%3D%5C%22sec2%5C%22%3E%3Ctitle%3EMethods%3C%5C%2Ftitle%3E%3Cp%3EBetween%202021%20and%202022%2C%20453%2010-%20to%2014-year-old%20children%20participating%20in%20the%20LIFE%20Child%20cohort%20study%20%28Germany%29%20reported%20on%20their%20use%20of%20electronic%20media%20%28daily%20screen%20time%2C%20use%20at%20bedtime%2C%20device%20ownership%29%20and%20on%20their%20sleep%20difficulties%20%28Sleep%20Self%20Report%29.%20Associations%20between%20media%20use%20and%20sleep%20as%20well%20as%20interactions%20with%20age%20and%20sex%20were%20assessed%20using%20linear%20regression%20analyses.%3C%5C%2Fp%3E%3C%5C%2Fsec%3E%3Csec%20id%3D%5C%22sec3%5C%22%3E%3Ctitle%3EResults%3C%5C%2Ftitle%3E%3Cp%3EThe%20analyses%20revealed%20significant%20associations%20between%20the%20use%20of%20media%20at%20bedtime%20and%20bedtime%20problems%20%28in%20girls%20only%29%2C%20sleep%20behavior%20problems%20%28in%20girls%20only%29%2C%20and%20daytime%20sleepiness%20%28in%20girls%20and%20boys%29.%20Daily%20screen%20time%2C%20in%20contrast%2C%20was%20associated%20with%20none%20of%20the%20sleep%20difficulties.%20The%20number%20of%20media%20devices%20owned%20by%20the%20child%20was%20only%20associated%20with%20bedtime%20problems%20in%20girls%2C%20and%20this%20association%20lost%20statistical%20significance%20once%20media%20use%20at%20bedtime%20was%20included%20as%20further%20predictor.%3C%5C%2Fp%3E%3C%5C%2Fsec%3E%3Csec%20id%3D%5C%22sec4%5C%22%3E%3Ctitle%3EConclusion%3C%5C%2Ftitle%3E%3Cp%3EThe%20findings%20underline%20the%20potentially%20sleep-disturbing%20role%20of%20electronic%20media%20at%20bedtime.%20Furthermore%2C%20they%20suggest%20that%20this%20effect%20is%20more%20pronounced%20in%20girls%20than%20in%20boys.%3C%5C%2Fp%3E%3C%5C%2Fsec%3E%22%2C%22date%22%3A%222024-07-12%22%2C%22language%22%3A%22English%22%2C%22DOI%22%3A%2210.3389%5C%2Ffpsyg.2024.1290935%22%2C%22ISSN%22%3A%221664-1078%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.frontiersin.org%5C%2Fjournals%5C%2Fpsychology%5C%2Farticles%5C%2F10.3389%5C%2Ffpsyg.2024.1290935%5C%2Ffull%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222024-07-18T17%3A24%3A58Z%22%7D%7D%2C%7B%22key%22%3A%225GVVR5GN%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Prenzel%20et%20al.%22%2C%22parsedDate%22%3A%222024-07-08%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EPrenzel%2C%20Freerk%2C%20Thorsten%20Kaiser%2C%20Anja%20Willenberg%2C%20Maike%20vom%20Hove%2C%20Gunter%20Flemming%2C%20Lars%20Fischer%2C%20J%26%23xFC%3Brgen%20Kratzsch%2C%20Wieland%20Kiess%2C%20and%20Mandy%20Vogel.%20%26%23x201C%3BReference%20Intervals%20and%20Percentiles%20for%20Soluble%20Transferrin%20Receptor%20and%20STfR%5C%2FLog%20Ferritin%20Index%20in%20Healthy%20Children%20and%20Adolescents.%26%23x201D%3B%20%3Ci%3EClinical%20Chemistry%20and%20Laboratory%20Medicine%20%28CCLM%29%3C%5C%2Fi%3E%2C%20July%208%2C%202024.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1515%5C%2Fcclm-2024-0369%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1515%5C%2Fcclm-2024-0369%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Reference%20intervals%20and%20percentiles%20for%20soluble%20transferrin%20receptor%20and%20sTfR%5C%2Flog%20ferritin%20index%20in%20healthy%20children%20and%20adolescents%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Freerk%22%2C%22lastName%22%3A%22Prenzel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Thorsten%22%2C%22lastName%22%3A%22Kaiser%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anja%22%2C%22lastName%22%3A%22Willenberg%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Maike%20vom%22%2C%22lastName%22%3A%22Hove%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Gunter%22%2C%22lastName%22%3A%22Flemming%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Lars%22%2C%22lastName%22%3A%22Fischer%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J%5Cu00fcrgen%22%2C%22lastName%22%3A%22Kratzsch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%5D%2C%22abstractNote%22%3A%22Objectives%20Soluble%20transferrin%20receptor%20%28sTfR%29%20is%20a%20marker%20of%20both%20erythropoiesis%20and%20iron%20status%20and%20is%20considered%20useful%20for%20detecting%20iron%20deficiency%2C%20especially%20in%20inflammatory%20conditions%2C%20but%20reference%20intervals%20covering%20the%20entire%20pediatric%20age%20spectrum%20are%20lacking.%20Methods%20We%20studied%201%2C064%20%2848.5%5Cu202f%25%20female%29%20healthy%20children%20of%20the%20entire%20pediatric%20age%20spectrum%20to%20determine%20reference%20values%20and%20percentiles%20for%20sTfR%20and%20the%20ratio%20of%20sTfR%20to%20log-ferritin%20%28sTfR-F%20index%29%20using%20a%20standard%20immunoturbidimetric%20assay.%20Results%20Soluble%20TfR%20levels%20were%20highly%20age-specific%2C%20with%20a%20peak%20in%20infancy%20and%20a%20decline%20in%20adulthood%2C%20whereas%20the%20sTfR-F%20index%20was%20a%20rather%20constant%20parameter.%20There%20were%20positive%20linear%20relationships%20for%20sTfR%20with%20hemoglobin%20%28Hb%29%20%28p%3D0.008%29%20and%20transferrin%20%28females%20p%26lt%3B0.001%3B%20males%20p%3D0.003%29.%20A%5Cu00a0negative%20association%20was%20observed%20between%20sTfR%20and%20ferritin%20in%20females%20%28p%26lt%3B0.0001%29%20and%20for%20transferrin%20saturation%20and%20mean%20corpuscular%20volume%20%28MCV%29%20in%20both%20sexes%20%28both%20p%26lt%3B0.0001%29.%20We%20found%20a%20positive%20relationship%20between%20sTfR%20and%20body%20height%2C%20body%20mass%20index%20%28BMI%29%20and%20inflammatory%20markers%20%28CrP%20p%26lt%3B0.0001%3B%20WBC%20p%3D0.0172%29%2C%20while%20sTfR-F%20index%20was%20not%20affected%20by%20inflammation.%20Conclusions%20Soluble%20TfR%20values%20appear%20to%20reflect%20the%20activity%20of%20infant%20erythropoiesis%20and%20to%20be%20modulated%20by%20inflammation%20and%20iron%20deficiency%20even%20in%20a%20healthy%20cohort.%22%2C%22date%22%3A%222024-07-08%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1515%5C%2Fcclm-2024-0369%22%2C%22ISSN%22%3A%221437-4331%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.degruyter.com%5C%2Fdocument%5C%2Fdoi%5C%2F10.1515%5C%2Fcclm-2024-0369%5C%2Fhtml%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222024-11-14T13%3A48%3A49Z%22%7D%7D%2C%7B%22key%22%3A%22BRTAYN7Z%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Ober%20et%20al.%22%2C%22parsedDate%22%3A%222024-06-19%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EOber%2C%20Peggy%2C%20Tanja%20Poulain%2C%20Christof%20Meigen%2C%20Ulrike%20Spielau%2C%20Carolin%20Sobek%2C%20Wieland%20Kiess%2C%20Ulrike%20Igel%2C%20Tobias%20Lipek%2C%20and%20Mandy%20Vogel.%20%26%23x201C%3BModifiable%20Factors%20Influencing%20Attention%20Performance%20in%20Healthy%20Children%3A%20Insights%20from%20a%20Comprehensive%20School%20Nutrition%20Study.%26%23x201D%3B%20%3Ci%3EBMC%20Public%20Health%3C%5C%2Fi%3E%2024%2C%20no.%201%20%28June%2019%2C%202024%29%3A%201629.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs12889-024-19059-8%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs12889-024-19059-8%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Modifiable%20factors%20influencing%20attention%20performance%20in%20healthy%20children%3A%20insights%20from%20a%20comprehensive%20school%20nutrition%20study%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Peggy%22%2C%22lastName%22%3A%22Ober%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christof%22%2C%22lastName%22%3A%22Meigen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ulrike%22%2C%22lastName%22%3A%22Spielau%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Carolin%22%2C%22lastName%22%3A%22Sobek%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ulrike%22%2C%22lastName%22%3A%22Igel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tobias%22%2C%22lastName%22%3A%22Lipek%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%5D%2C%22abstractNote%22%3A%22BACKGROUND%3A%20There%20is%20inconclusive%20evidence%20for%20the%20effects%20of%20various%20leisure%20activities%20on%20attention%20performance%20in%20children.%20The%20literature%20reports%20inconsistent%20associations%20between%20activities%20such%20as%20physical%20activities%20or%20media%20use.%20To%20date%2C%20no%20study%20has%20thoroughly%20examined%20the%20various%20factors%20influencing%20attentional%20performance%20in%20a%20larger%20cohort%20of%20healthy%20children.%20This%20study%20aims%20to%20close%20this%20research%20gap.%5CnMETHODS%3A%20From%202018%20to%202019%2C%20the%20Leipzig%20School%20Nutrition%20Study%20collected%20data%20from%201215%20children%20and%20their%20families.%20The%20children%20report%20their%20dietary%20behavior%20%28using%20CoCu-%20Questionnaire%29%2C%20especially%20their%20participation%20in%20school%20lunch%20and%20their%20breakfast%20habits%2C%20through%20a%20paper%20questionnaire.%20Furthermore%2C%20attention%20performance%20was%20assessed%20using%20a%20validated%20test%20%28FAIR-2%29%20at%20school.%20Data%20on%20physical%20activity%2C%20media%20consumption%2C%20family%20eating%20habits%20and%20socio-economic%20status%20%28SES%29%20were%20collected%20from%20parents%20using%20questionnaires.%20Associations%20between%20attention%20and%20influencing%20factors%20were%20estimated%20using%20hierarchical%20linear%20regression.%20Analyses%20were%20adjusted%20for%20age%2C%20SES%2C%20and%20school%20type.%5CnRESULTS%3A%20Attending%20upper%20secondary%20schools%20%28%5Cu00dfadj%3D%2023.6%2C%20p%5Cu2009%3C%5Cu20090.001%29%20and%20having%20a%20higher%20SES%20%28%5Cu00df%3D%201.28%2C%20p%5Cu2009%3C%5Cu20090.001%29%20was%20associated%20with%20higher%20attention%20performance.%20Children%20doing%20leisure-time%20sports%20%28%5Cu00dfadj%3D%204.18%2C%20p%5Cu2009%3D%5Cu20090.046%29%20or%20reading%20books%20for%20at%20least%20one%20hour%5C%2Fweekday%20showed%20better%20attention%20performance%20%28%5Cu00dfadj%3D%203.8%2C%20p%5Cu2009%3D%5Cu20090.040%29.%20Attention%20performance%20was%20also%20better%20in%20children%20having%20no%20electronic%20devices%20in%20the%20bedroom%20%28%5Cu00dfadj%3D%2013.0%2C%20p%5Cu2009%3D%5Cu20090.005%29%20and%20in%20children%20whose%20parents%20limited%20their%20children%27s%20Internet%20access%20%28%5Cu00dfadj%3D%205.2%2C%20p%5Cu2009%3D%5Cu20090.012%29.%20We%20did%20not%20find%20any%20association%20between%20nutritional%20habits%20and%20attention%20performance.%5CnCONCLUSIONS%3A%20We%20found%20that%20fostering%20modifiable%20habits%20such%20as%20reading%20and%20physical%20activity%20could%20enhance%20attention%20performance.%20These%20findings%20have%20substantial%20implications%20for%20the%20development%20of%20prevention%20and%20intervention%20programs%20that%20aim%20to%20improve%20attention%20in%20schoolchildren.%20It%20is%20important%20to%20note%2C%20however%2C%20that%20social%20status%20as%20a%20hardly%20modifiable%20factor%20also%20impacts%20attention%20performance.%20Therefore%2C%20interventions%20should%20address%20personal%20habits%20in%20a%20systemic%20approach%20considering%20the%20child%27s%20social%20status.%5CnTRIAL%20REGISTRATION%3A%20The%20study%20is%20retrospectively%20registered%20with%20the%20German%20Clinical%20Trials%20Register%20%28DRKS00017317%2C%20registration%3A%2005-29-2019%29.%22%2C%22date%22%3A%222024-06-19%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1186%5C%2Fs12889-024-19059-8%22%2C%22ISSN%22%3A%221471-2458%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222024-08-27T12%3A26%3A19Z%22%7D%7D%2C%7B%22key%22%3A%22K5XMVMIN%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Fechner%20et%20al.%22%2C%22parsedDate%22%3A%222024-06-15%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EFechner%2C%20Anna%2C%20Anja%20Willenberg%2C%20Niels%20Ziegelasch%2C%20Andreas%20Merkenschlager%2C%20Wieland%20Kiess%2C%20and%20Mandy%20Vogel.%20%26%23x201C%3BCreatine%20Kinase%20Serum%20Levels%20in%20Children%20Revisited%3A%20New%20Reference%20Intervals%20from%20a%20Large%20Cohort%20of%20Healthy%20Children%20and%20Adolescents.%26%23x201D%3B%20%3Ci%3EClinica%20Chimica%20Acta%3C%5C%2Fi%3E%20560%20%28June%2015%2C%202024%29%3A%20119726.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.cca.2024.119726%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.cca.2024.119726%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Creatine%20kinase%20serum%20levels%20in%20children%20revisited%3A%20New%20reference%20intervals%20from%20a%20large%20cohort%20of%20healthy%20children%20and%20adolescents%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anna%22%2C%22lastName%22%3A%22Fechner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anja%22%2C%22lastName%22%3A%22Willenberg%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Niels%22%2C%22lastName%22%3A%22Ziegelasch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andreas%22%2C%22lastName%22%3A%22Merkenschlager%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%5D%2C%22abstractNote%22%3A%22Background%5CnCreatine%20Kinase%20%28CK%29%20has%20become%20increasingly%20important%20in%20pediatrics%20as%20a%20commonly%20used%20laboratory%20screening%20parameter%20for%20neuromuscular%20diseases.%20Recent%20research%20suggests%20that%20hyperCKemia%20in%20children%20is%20not%20always%20associated%20with%20pathology%20and%20can%20occur%20due%20to%20several%20reasons.%20Little%20is%20known%20of%20various%20clinical%20factors%20that%20may%20influence%20CK%20throughout%20child%20development.%5CnObjective%5CnThis%20study%20aimed%20to%20establish%20reliable%20age-%20and%20sex-specific%20reference%20ranges%20for%20serum%20CK%20levels%20in%20healthy%20infants%2C%20children%2C%20and%20adolescents.%20In%20addition%2C%20the%20effect%20of%20puberty%2C%20oral%20contraceptive%20%28OC%29%20use%20as%20well%20as%20steroid%20hormones%20on%20CK%20was%20examined.%5CnMaterials%20and%20methods%5CnThe%20data%20was%20collected%20from%20subjects%20of%20the%20longitudinal%20population-based%20%5Cu201cLIFE%20Child%5Cu201d-cohort%20between%202011%20and%202016%20in%20Leipzig%2C%20Germany.%205238%20blood%20samples%20of%202707%20healthy%20children%2C%20aged%20between%200.14%5Cu00a0months%20and%2018%5Cu00a0years%2C%20were%20analyzed.%5CnResults%5CnSerum%20CK%20levels%20raised%20during%20the%20first%20year%20of%20life%2C%20peaking%20shortly%20after%20age%20one%20%28P50girls%5Cu00a0%3D%5Cu00a02.7%20%5Cu00b5kat%5C%2FL%2C%20P50boys%5Cu00a0%3D%5Cu00a02.90%20%5Cu00b5kat%5C%2FL%29.%20There%20was%20a%20pronounced%20difference%20in%20the%2097.5th%20percentile%20between%20boys%20and%20girls%20during%20adolescence%20with%20its%20maximum%20at%20age%2018%20%28P97.5girls%5Cu00a0%3D%5Cu00a05.74%20%5Cu00b5kat%5C%2FL%2C%20P97.5boys%3D%2014.48%20%5Cu00b5kat%5C%2FL%29.%20Also%2C%20mean%20CK%20serum%20levels%20were%20significantly%20higher%20in%20boys%20%28bboys%5Cu00a0%3D%5Cu00a00.29%2C%20pboys%5Cu00a0%3C%5Cu00a00.001%29.%20Intake%20of%20oral%20contraceptives%20%28OC%29%2C%20extreme%20underweight%2C%20underweight%20and%20obesity%20revealed%20a%20significant%20inverse%20correlation%20with%20CK%20serum%20levels.%5CnConclusion%5CnAge%2C%20sex%2C%20OC%20intake%20and%20weight%20status%20affect%20serum%20CK%20levels%2C%20particularly%20during%20infancy%20and%20puberty.%20We%20recommend%20the%20use%20of%20age-%20and%20sex-specific%20reference%20values%20for%20CK%20serum%20levels%20to%20assess%20the%20clinical%20relevance%20of%20measurements.%22%2C%22date%22%3A%222024-06-15%22%2C%22language%22%3A%22%22%2C%22DOI%22%3A%2210.1016%5C%2Fj.cca.2024.119726%22%2C%22ISSN%22%3A%220009-8981%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.sciencedirect.com%5C%2Fscience%5C%2Farticle%5C%2Fpii%5C%2FS0009898124019788%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222024-06-04T05%3A31%3A27Z%22%7D%7D%2C%7B%22key%22%3A%22I6AVCS6H%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Tomar%20et%20al.%22%2C%22parsedDate%22%3A%222024-06-05%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3ETomar%2C%20A.%2C%20M.%20Gomez-Velazquez%2C%20R.%20Gerlini%2C%20G.%20Comas-Armangu%26%23xE9%3B%2C%20L.%20Makharadze%2C%20T.%20Kolbe%2C%20A.%20Boersma%2C%20et%20al.%20%26%23x201C%3BEpigenetic%20Inheritance%20of%20Diet-Induced%20and%20Sperm-Borne%20Mitochondrial%20RNAs.%26%23x201D%3B%20%3Ci%3ENature%3C%5C%2Fi%3E%2C%20June%205%2C%202024%2C%201%26%23×2013%3B8.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1038%5C%2Fs41586-024-07472-3%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1038%5C%2Fs41586-024-07472-3%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Epigenetic%20inheritance%20of%20diet-induced%20and%20sperm-borne%20mitochondrial%20RNAs%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22A.%22%2C%22lastName%22%3A%22Tomar%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22M.%22%2C%22lastName%22%3A%22Gomez-Velazquez%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22R.%22%2C%22lastName%22%3A%22Gerlini%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22G.%22%2C%22lastName%22%3A%22Comas-Armangu%5Cu00e9%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22L.%22%2C%22lastName%22%3A%22Makharadze%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22T.%22%2C%22lastName%22%3A%22Kolbe%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22A.%22%2C%22lastName%22%3A%22Boersma%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22M.%22%2C%22lastName%22%3A%22Dahlhoff%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J.%20P.%22%2C%22lastName%22%3A%22Burgstaller%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22M.%22%2C%22lastName%22%3A%22Lassi%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J.%22%2C%22lastName%22%3A%22Darr%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J.%22%2C%22lastName%22%3A%22Toppari%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22H.%22%2C%22lastName%22%3A%22Virtanen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22A.%22%2C%22lastName%22%3A%22K%5Cu00fchnapfel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22M.%22%2C%22lastName%22%3A%22Scholz%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22K.%22%2C%22lastName%22%3A%22Landgraf%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22W.%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22M.%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22V.%22%2C%22lastName%22%3A%22Gailus-Durner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22H.%22%2C%22lastName%22%3A%22Fuchs%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22S.%22%2C%22lastName%22%3A%22Marschall%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22M.%22%2C%22lastName%22%3A%22Hrab%5Cu011b%20de%20Angelis%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22N.%22%2C%22lastName%22%3A%22Kotaja%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22A.%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22R.%22%2C%22lastName%22%3A%22Teperino%22%7D%5D%2C%22abstractNote%22%3A%22Spermatozoa%20harbour%20a%20complex%20and%20environment-sensitive%20pool%20of%20small%20non-coding%20RNAs%20%28sncRNAs%291%2C%20which%20influences%20offspring%20development%20and%20adult%20phenotypes1%5Cu20137.%20Whether%20spermatozoa%20in%20the%20epididymis%20are%20directly%20susceptible%20to%20environmental%20cues%20is%20not%20fully%20understood8.%20Here%20we%20used%20two%20distinct%20paradigms%20of%20preconception%20acute%20high-fat%20diet%20to%20dissect%20epididymal%20versus%20testicular%20contributions%20to%20the%20sperm%20sncRNA%20pool%20and%20offspring%20health.%20We%20show%20that%20epididymal%20spermatozoa%2C%20but%20not%20developing%20germ%20cells%2C%20are%20sensitive%20to%20the%20environment%20and%20identify%20mitochondrial%20tRNAs%20%28mt-tRNAs%29%20and%20their%20fragments%20%28mt-tsRNAs%29%20as%20sperm-borne%20factors.%20In%20humans%2C%20mt-tsRNAs%20in%20spermatozoa%20correlate%20with%20body%20mass%20index%2C%20and%20paternal%20overweight%20at%20conception%20doubles%20offspring%20obesity%20risk%20and%20compromises%20metabolic%20health.%20Sperm%20sncRNA%20sequencing%20of%20mice%20mutant%20for%20genes%20involved%20in%20mitochondrial%20function%2C%20and%20metabolic%20phenotyping%20of%20their%20wild-type%20offspring%2C%20suggest%20that%20the%20upregulation%20of%20mt-tsRNAs%20is%20downstream%20of%20mitochondrial%20dysfunction.%20Single-embryo%20transcriptomics%20of%20genetically%20hybrid%20two-cell%20embryos%20demonstrated%20sperm-to-oocyte%20transfer%20of%20mt-tRNAs%20at%20fertilization%20and%20suggested%20their%20involvement%20in%20the%20control%20of%20early-embryo%20transcription.%20Our%20study%20supports%20the%20importance%20of%20paternal%20health%20at%20conception%20for%20offspring%20metabolism%2C%20shows%20that%20mt-tRNAs%20are%20diet-induced%20and%20sperm-borne%20and%20demonstrates%2C%20in%20a%20physiological%20setting%2C%20father-to-offspring%20transfer%20of%20sperm%20mitochondrial%20RNAs%20at%20fertilization.%22%2C%22date%22%3A%222024-06-05%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1038%5C%2Fs41586-024-07472-3%22%2C%22ISSN%22%3A%221476-4687%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.nature.com%5C%2Farticles%5C%2Fs41586-024-07472-3%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222024-08-27T12%3A32%3A38Z%22%7D%7D%2C%7B%22key%22%3A%22W8FWC32V%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Ravi%20Teja%20et%20al.%22%2C%22parsedDate%22%3A%222024-05-15%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3ERavi%20Teja%2C%20Kasagani%20Venkata%2C%20Bhanu%20Malhotra%2C%20Mandy%20Vogel%2C%20Raman%20Kumar%20Marwaha%2C%20Arun%20Aggarwal%2C%20Rimesh%20Pal%2C%20Liza%20Das%2C%20et%20al.%20%26%23x201C%3BNormative%20Data%20for%20Insulin-like%20Growth%20Factor-1%20%28IGF-1%29%20in%20Healthy%20Children%20and%20Adolescents%20from%20India.%26%23x201D%3B%20%3Ci%3EThe%20Journal%20of%20Clinical%20Endocrinology%20and%20Metabolism%3C%5C%2Fi%3E%2C%20May%2015%2C%202024%2C%20dgae340.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F2024061217375967200%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F2024061217375967200%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Normative%20data%20for%20insulin-like%20growth%20factor-1%20%28IGF-1%29%20in%20healthy%20children%20and%20adolescents%20from%20India%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Kasagani%20Venkata%22%2C%22lastName%22%3A%22Ravi%20Teja%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Bhanu%22%2C%22lastName%22%3A%22Malhotra%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Raman%20Kumar%22%2C%22lastName%22%3A%22Marwaha%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Arun%22%2C%22lastName%22%3A%22Aggarwal%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Rimesh%22%2C%22lastName%22%3A%22Pal%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Liza%22%2C%22lastName%22%3A%22Das%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Naresh%22%2C%22lastName%22%3A%22Sachdeva%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Nagita%22%2C%22lastName%22%3A%22Devi%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Dipika%22%2C%22lastName%22%3A%22Bansal%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ashu%22%2C%22lastName%22%3A%22Rastogi%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Sadhna%22%2C%22lastName%22%3A%22Sharma%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Dewan%22%2C%22lastName%22%3A%22Gajinder%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Sanjay%20Kumar%22%2C%22lastName%22%3A%22Bhadada%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jayaditya%22%2C%22lastName%22%3A%22Ghosh%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Phillip%20J.%22%2C%22lastName%22%3A%22Monaghan%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22M%5Cu00e1rta%22%2C%22lastName%22%3A%22Korbonits%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Pinaki%22%2C%22lastName%22%3A%22Dutta%22%7D%5D%2C%22abstractNote%22%3A%22BACKGROUND%3A%20Serum%20IGF-1%20is%20an%20important%20biochemical%20tool%20to%20diagnose%20and%20monitor%20GH-related%20disorders.%20However%2C%20ethnic-specific%20Indian%20data%20following%20consensus%20criteria%20for%20the%20establishment%20of%20normative%20data%2C%20are%20not%20available.%20Our%20objective%20was%20to%20generate%20chronological%20age%20%28CA%29-%2C%20bone%20age%20%28BA%29-%20and%20Tanner%20stage-specific%20normative%20data%20for%20IGF-1%20in%20healthy%20Indian%20children%20and%20adolescents.%5CnMETHODS%3A%20A%20cross-sectional%20epidemiological%20study%20was%20conducted%20in%20schools%20and%20the%20community%2C%20which%20enrolled%20apparently%20healthy%20children%20and%20adolescents%20with%20robust%20exclusion%20criteria.%20The%20outcome%20measure%20was%20serum%20IGF-1%20assessed%20using%20an%20electro-chemiluminescence%20immunoassay%20%28ECLIA%29.%20The%202.5th%2C%205th%2C%2010th%2C%2025th%2C%2050th%20%28median%29%2C%2075th%2C%2090th%2C%2095th%2C%20and%2097.5th%20centiles%20for%20IGF-1%20were%20estimated%20using%20generalized%20additive%20models.%5CnRESULTS%3A%20We%20recruited%202226%20apparently%20healthy%20participants%20and%20following%20exclusion%2C%201948%20%281006%20boys%2C%20942%20girls%29%20were%20included%20in%20the%20final%20analysis.%20Girls%20had%20median%20IGF-1%20peak%20at%20CA%20of%2013%20years%20%28321.7%5Cu2005ng%5C%2FmL%29%2C%20BA%20of%2014%20years%20%28350.2%5Cu2005ng%5C%2FmL%29%20and%20Tanner%20stage%20IV%20%28345%5Cu2005ng%5C%2FmL%29%2C%20while%20boys%20had%20median%20IGF-1%20peak%20at%20CA%20of%2015%20years%20%28318.9%5Cu2005ng%5C%2FmL%29%20BA%20of%2015%20years%20%28340.6%5Cu2005ng%5C%2FmL%29%20and%20Tanner%20stage%20III%20%28304.8%5Cu2005ng%5C%2FmL%29.%20Girls%20had%20earlier%20rise%2C%20peak%20and%20higher%20IGF-1%20values.%20The%20reference%20interval%20%282.5th-97.5th%20percentile%29%20was%20broader%20during%20peri-pubertal%20ages%2C%20indicating%20a%20higher%20physiological%20variability.%5CnCONCLUSION%3A%20This%20study%20provides%20ethnicity-specific%20normative%20data%20on%20serum%20IGF-1%20and%20will%20improve%20the%20diagnostic%20utility%20of%20IGF-1%20in%20the%20evaluation%20and%20management%20of%20growth%20disorders%20in%20Indian%20children%20and%20adolescents.%22%2C%22date%22%3A%222024-05-15%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%222024061217375967200%22%2C%22ISSN%22%3A%221945-7197%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222024-08-27T12%3A34%3A44Z%22%7D%7D%2C%7B%22key%22%3A%22EB3A53J6%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Barzen%20et%20al.%22%2C%22parsedDate%22%3A%222024-04-13%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EBarzen%2C%20Charlotte%2C%20Mandy%20Vogel%2C%20Wieland%20Kiess%2C%20and%20Tanja%20Poulain.%20%26%23x201C%3BAssociations%20between%20Gestational%20Weight%20Gain%20and%20Weight%20Development%20of%20the%20Offspring%3A%20Differences%20Depending%20on%20Maternal%20Pre-Pregnancy%20BMI.%26%23x201D%3B%20%3Ci%3EArchives%20of%20Gynecology%20and%20Obstetrics%3C%5C%2Fi%3E%2C%20April%2013%2C%202024.%20%3Ca%20class%3D%27zp-ItemURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs00404-024-07487-1%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs00404-024-07487-1%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Associations%20between%20gestational%20weight%20gain%20and%20weight%20development%20of%20the%20offspring%3A%20Differences%20depending%20on%20maternal%20pre-pregnancy%20BMI%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Charlotte%22%2C%22lastName%22%3A%22Barzen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%5D%2C%22abstractNote%22%3A%22Obesity%20rates%20are%20rising%2C%20and%20the%20gestational%20weight%20gain%20%28GWG%29%20of%20most%20women%20does%20not%20comply%20with%20current%20guidelines.%20This%20study%20assesses%20the%20association%20of%20pre-pregnancy%20BMI%20%28ppBMI%29%20and%20GWG%20with%20the%20child%5Cu2019s%20weight%20development%20and%20investigates%20whether%20associations%20with%20GWG%20differ%20depending%20on%20ppBMI.%22%2C%22date%22%3A%222024-04-13%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1007%5C%2Fs00404-024-07487-1%22%2C%22ISSN%22%3A%221432-0711%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs00404-024-07487-1%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222024-04-15T06%3A03%3A53Z%22%7D%7D%2C%7B%22key%22%3A%22A483R4YA%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22St%5Cu00fcrzebecher%20et%20al.%22%2C%22parsedDate%22%3A%222024-02-28%22%2C%22numChildren%22%3A2%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3ESt%26%23xFC%3Brzebecher%2C%20Paulina%20E.%2C%20Konstantin%20L.%20Uttinger%2C%20Mandy%20Vogel%2C%20Maike%20Schlingmann%2C%20Uta%20Ceglarek%2C%20Berend%20Isermann%2C%20Wieland%20Kiess%2C%20Antje%20K%26%23xF6%3Brner%2C%20and%20Ulrich%20Laufs.%20%26%23x201C%3BLipoprotein%28a%29%20Serum%20Concentrations%20in%20Children%20in%20Relation%20to%20Body%20Mass%20Index%2C%20Age%20and%20Sex.%26%23x201D%3B%20%3Ci%3EPediatric%20Research%3C%5C%2Fi%3E%2C%20February%2028%2C%202024.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1038%5C%2Fs41390-024-03108-4%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1038%5C%2Fs41390-024-03108-4%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Lipoprotein%28a%29%20serum%20concentrations%20in%20children%20in%20relation%20to%20body%20mass%20index%2C%20age%20and%20sex%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Paulina%20E.%22%2C%22lastName%22%3A%22St%5Cu00fcrzebecher%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Konstantin%20L.%22%2C%22lastName%22%3A%22Uttinger%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Maike%22%2C%22lastName%22%3A%22Schlingmann%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Uta%22%2C%22lastName%22%3A%22Ceglarek%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Berend%22%2C%22lastName%22%3A%22Isermann%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ulrich%22%2C%22lastName%22%3A%22Laufs%22%7D%5D%2C%22abstractNote%22%3A%22BACKGROUND%3A%20Lipoprotein%28a%29%20%28Lp%28a%29%29%20is%20an%20inherited%20risk%20factor%20for%20atherosclerotic%20cardiovascular%20disease%20%28ASCVD%29.%20Limited%20data%20exist%20on%20Lp%28a%29%20values%20in%20children.%20We%20aimed%20to%20evaluate%20whether%20Lp%28a%29%20concentrations%20in%20youth%20are%20influenced%20by%20BMI.%5CnMETHODS%3A%20756%20blood%20samples%20of%20248%20children%20with%20obesity%20and%20264%20matched%20healthy%20children%20aged%205%20and%2018%20years%2C%20enrolled%20in%20the%20population-based%20LIFE%20Child%20%28German%20civilization%20diseases%20cohort%29%20study%2C%20were%20analyzed.%20Repeat%20measurements%20were%20available%20in%20154%20children%20%281-4%20follow%20ups%2C%20~1%20year%20apart%29.%5CnRESULTS%3A%20The%20median%20Lp%28a%29%20concentration%20in%20the%20total%20cohort%20%28n%5Cu2009%3D%5Cu2009512%29%20at%20first%20visit%20was%209.7%5Cu2009mg%5C%2FdL%20%28IQR%204.0-28.3%29.%20Lp%28a%29%20concentrations%20between%2030-50%5Cu2009mg%5C%2FdL%20were%20observed%20in%2011.5%25%2C%20while%2012.5%25%20exhibited%20Lp%28a%29%20%5Cu226750%5Cu2009mg%5C%2FdL.%20There%20was%20no%20association%20of%20Lp%28a%29%20with%20body%20mass%20index%20%28BMI%29%20%28%5Cu00df%5Cu2009%3D%5Cu20090.004%2C%20P%5Cu2009%3D%5Cu20090.49%29.%20Lp%28a%29%20levels%20did%20not%20correlate%20with%20age%20or%20sex%2C%20while%20Lp%28a%29%20was%20associated%20positively%20with%20low-density%20lipoprotein%20cholesterol%20%28%5Cu00df%5Cu2009%3D%5Cu20090.05%2C%20P%5Cu2009%3C%5Cu20090.0001%29.%20The%20Lp%28a%29%20risk%20category%20remained%20stable%20in%2094%25%20of%20all%20children%20in%20repeated%20measurements.%5CnCONCLUSIONS%3A%20The%20data%20showed%20no%20association%20of%20Lp%28a%29%20levels%20in%20children%20with%20BMI%2C%20age%20or%20sex.%20Measurement%20of%20Lp%28a%29%20in%20youth%20may%20be%20useful%20to%20identify%20children%20at%20increased%20lifetime%20risk%20for%20ASCVD.%5CnIMPACT%3A%20In%20youth%2C%20Lp%28a%29%20levels%20are%20not%20affected%20by%20age%2C%20sex%20and%20BMI.%20Lp%28a%29%20risk%20categories%20remain%20stable%20over%20time%20in%20repeated%20measurements%20in%20children.%20Measurement%20of%20Lp%28a%29%20in%20children%20may%20be%20useful%20as%20an%20additional%20factor%20to%20identify%20children%20at%20increased%20lifetime%20risk%20for%20ASCVD%20and%20for%20reverse%20family%20screening.%22%2C%22date%22%3A%222024-02-28%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1038%5C%2Fs41390-024-03108-4%22%2C%22ISSN%22%3A%221530-0447%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222024-03-06T09%3A08%3A28Z%22%7D%7D%2C%7B%22key%22%3A%2248EEZCMG%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Scholz%20et%20al.%22%2C%22parsedDate%22%3A%222024-01-18%22%2C%22numChildren%22%3A2%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EScholz%2C%20Markus%2C%20Katrin%20Horn%2C%20Janne%20Pott%2C%20Matthias%20Wuttke%2C%20Andreas%20K%26%23xFC%3Bhnapfel%2C%20M.%20Kamal%20Nasr%2C%20Holger%20Kirsten%2C%20et%20al.%20%26%23x201C%3BX-Chromosome%20and%20Kidney%20Function%3A%20Evidence%20from%20a%20Multi-Trait%20Genetic%20Analysis%20of%20908%2C697%20Individuals%20Reveals%20Sex-Specific%20and%20Sex-Differential%20Findings%20in%20Genes%20Regulated%20by%20Androgen%20Response%20Elements.%26%23x201D%3B%20%3Ci%3ENature%20Communications%3C%5C%2Fi%3E%2015%2C%20no.%201%20%28January%2018%2C%202024%29%3A%20586.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1038%5C%2Fs41467-024-44709-1%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1038%5C%2Fs41467-024-44709-1%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22X-chromosome%20and%20kidney%20function%3A%20evidence%20from%20a%20multi-trait%20genetic%20analysis%20of%20908%2C697%20individuals%20reveals%20sex-specific%20and%20sex-differential%20findings%20in%20genes%20regulated%20by%20androgen%20response%20elements%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Markus%22%2C%22lastName%22%3A%22Scholz%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Katrin%22%2C%22lastName%22%3A%22Horn%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Janne%22%2C%22lastName%22%3A%22Pott%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Matthias%22%2C%22lastName%22%3A%22Wuttke%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andreas%22%2C%22lastName%22%3A%22K%5Cu00fchnapfel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22M.%20Kamal%22%2C%22lastName%22%3A%22Nasr%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Holger%22%2C%22lastName%22%3A%22Kirsten%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Yong%22%2C%22lastName%22%3A%22Li%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anselm%22%2C%22lastName%22%3A%22Hoppmann%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mathias%22%2C%22lastName%22%3A%22Gorski%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Sahar%22%2C%22lastName%22%3A%22Ghasemi%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Man%22%2C%22lastName%22%3A%22Li%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Adrienne%22%2C%22lastName%22%3A%22Tin%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jin-Fang%22%2C%22lastName%22%3A%22Chai%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Massimiliano%22%2C%22lastName%22%3A%22Cocca%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Judy%22%2C%22lastName%22%3A%22Wang%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Teresa%22%2C%22lastName%22%3A%22Nutile%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Masato%22%2C%22lastName%22%3A%22Akiyama%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Bj%5Cu00f8rn%20Olav%22%2C%22lastName%22%3A%22%5Cu00c5svold%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Nisha%22%2C%22lastName%22%3A%22Bansal%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mary%20L.%22%2C%22lastName%22%3A%22Biggs%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Thibaud%22%2C%22lastName%22%3A%22Boutin%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Hermann%22%2C%22lastName%22%3A%22Brenner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ben%22%2C%22lastName%22%3A%22Brumpton%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ralph%22%2C%22lastName%22%3A%22Burkhardt%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jianwen%22%2C%22lastName%22%3A%22Cai%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Archie%22%2C%22lastName%22%3A%22Campbell%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Harry%22%2C%22lastName%22%3A%22Campbell%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22John%22%2C%22lastName%22%3A%22Chalmers%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Daniel%20I.%22%2C%22lastName%22%3A%22Chasman%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Miao%20Ling%22%2C%22lastName%22%3A%22Chee%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Miao%20Li%22%2C%22lastName%22%3A%22Chee%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Xu%22%2C%22lastName%22%3A%22Chen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ching-Yu%22%2C%22lastName%22%3A%22Cheng%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Renata%22%2C%22lastName%22%3A%22Cifkova%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Martha%22%2C%22lastName%22%3A%22Daviglus%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Graciela%22%2C%22lastName%22%3A%22Delgado%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Katalin%22%2C%22lastName%22%3A%22Dittrich%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Todd%20L.%22%2C%22lastName%22%3A%22Edwards%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Karlhans%22%2C%22lastName%22%3A%22Endlich%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J.%22%2C%22lastName%22%3A%22Michael%20Gaziano%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ayush%22%2C%22lastName%22%3A%22Giri%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Franco%22%2C%22lastName%22%3A%22Giulianini%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Scott%20D.%22%2C%22lastName%22%3A%22Gordon%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Daniel%20F.%22%2C%22lastName%22%3A%22Gudbjartsson%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Stein%22%2C%22lastName%22%3A%22Hallan%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Pavel%22%2C%22lastName%22%3A%22Hamet%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Catharina%20A.%22%2C%22lastName%22%3A%22Hartman%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Caroline%22%2C%22lastName%22%3A%22Hayward%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Iris%20M.%22%2C%22lastName%22%3A%22Heid%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jacklyn%20N.%22%2C%22lastName%22%3A%22Hellwege%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Bernd%22%2C%22lastName%22%3A%22Holleczek%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Hilma%22%2C%22lastName%22%3A%22Holm%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Nina%22%2C%22lastName%22%3A%22Hutri-K%5Cu00e4h%5Cu00f6nen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Kristian%22%2C%22lastName%22%3A%22Hveem%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Berend%22%2C%22lastName%22%3A%22Isermann%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jost%20B.%22%2C%22lastName%22%3A%22Jonas%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Peter%20K.%22%2C%22lastName%22%3A%22Joshi%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Yoichiro%22%2C%22lastName%22%3A%22Kamatani%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Masahiro%22%2C%22lastName%22%3A%22Kanai%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mika%22%2C%22lastName%22%3A%22Kastarinen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Chiea%20Chuen%22%2C%22lastName%22%3A%22Khor%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Marcus%20E.%22%2C%22lastName%22%3A%22Kleber%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Peter%22%2C%22lastName%22%3A%22Kovacs%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Alena%22%2C%22lastName%22%3A%22Krajcoviechova%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Holly%22%2C%22lastName%22%3A%22Kramer%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Bernhard%20K.%22%2C%22lastName%22%3A%22Kr%5Cu00e4mer%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mikko%22%2C%22lastName%22%3A%22Kuokkanen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mika%22%2C%22lastName%22%3A%22K%5Cu00e4h%5Cu00f6nen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Leslie%20A.%22%2C%22lastName%22%3A%22Lange%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22James%20P.%22%2C%22lastName%22%3A%22Lash%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Terho%22%2C%22lastName%22%3A%22Lehtim%5Cu00e4ki%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Hengtong%22%2C%22lastName%22%3A%22Li%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Bridget%20M.%22%2C%22lastName%22%3A%22Lin%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jianjun%22%2C%22lastName%22%3A%22Liu%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Markus%22%2C%22lastName%22%3A%22Loeffler%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Leo-Pekka%22%2C%22lastName%22%3A%22Lyytik%5Cu00e4inen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Patrik%20K.%20E.%22%2C%22lastName%22%3A%22Magnusson%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Nicholas%20G.%22%2C%22lastName%22%3A%22Martin%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Koichi%22%2C%22lastName%22%3A%22Matsuda%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Yuri%22%2C%22lastName%22%3A%22Milaneschi%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Pashupati%20P.%22%2C%22lastName%22%3A%22Mishra%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Nina%22%2C%22lastName%22%3A%22Mononen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Grant%20W.%22%2C%22lastName%22%3A%22Montgomery%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Dennis%20O.%22%2C%22lastName%22%3A%22Mook-Kanamori%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Josyf%20C.%22%2C%22lastName%22%3A%22Mychaleckyj%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Winfried%22%2C%22lastName%22%3A%22M%5Cu00e4rz%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Matthias%22%2C%22lastName%22%3A%22Nauck%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Kjell%22%2C%22lastName%22%3A%22Nikus%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ilja%20M.%22%2C%22lastName%22%3A%22Nolte%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Raymond%22%2C%22lastName%22%3A%22Noordam%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Yukinori%22%2C%22lastName%22%3A%22Okada%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Isleifur%22%2C%22lastName%22%3A%22Olafsson%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Albertine%20J.%22%2C%22lastName%22%3A%22Oldehinkel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Brenda%20W.%20J.%20H.%22%2C%22lastName%22%3A%22Penninx%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Markus%22%2C%22lastName%22%3A%22Perola%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Nicola%22%2C%22lastName%22%3A%22Pirastu%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ozren%22%2C%22lastName%22%3A%22Polasek%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22David%20J.%22%2C%22lastName%22%3A%22Porteous%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Bruce%20M.%22%2C%22lastName%22%3A%22Psaty%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ton%20J.%22%2C%22lastName%22%3A%22Rabelink%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Laura%20M.%22%2C%22lastName%22%3A%22Raffield%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Olli%20T.%22%2C%22lastName%22%3A%22Raitakari%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Humaira%22%2C%22lastName%22%3A%22Rasheed%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Dermot%20F.%22%2C%22lastName%22%3A%22Reilly%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Kenneth%20M.%22%2C%22lastName%22%3A%22Rice%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anne%22%2C%22lastName%22%3A%22Richmond%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Paul%20M.%22%2C%22lastName%22%3A%22Ridker%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jerome%20I.%22%2C%22lastName%22%3A%22Rotter%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Igor%22%2C%22lastName%22%3A%22Rudan%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Charumathi%22%2C%22lastName%22%3A%22Sabanayagam%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Veikko%22%2C%22lastName%22%3A%22Salomaa%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Neil%22%2C%22lastName%22%3A%22Schneiderman%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ben%22%2C%22lastName%22%3A%22Sch%5Cu00f6ttker%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mario%22%2C%22lastName%22%3A%22Sims%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Harold%22%2C%22lastName%22%3A%22Snieder%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Klaus%20J.%22%2C%22lastName%22%3A%22Stark%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Kari%22%2C%22lastName%22%3A%22Stefansson%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Hannah%22%2C%22lastName%22%3A%22Stocker%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Michael%22%2C%22lastName%22%3A%22Stumvoll%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Patrick%22%2C%22lastName%22%3A%22Sulem%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Gardar%22%2C%22lastName%22%3A%22Sveinbjornsson%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Per%20O.%22%2C%22lastName%22%3A%22Svensson%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22E.-Shyong%22%2C%22lastName%22%3A%22Tai%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Kent%20D.%22%2C%22lastName%22%3A%22Taylor%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Bamidele%20O.%22%2C%22lastName%22%3A%22Tayo%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andrej%22%2C%22lastName%22%3A%22Teren%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Yih-Chung%22%2C%22lastName%22%3A%22Tham%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Joachim%22%2C%22lastName%22%3A%22Thiery%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Chris%20H.%20L.%22%2C%22lastName%22%3A%22Thio%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Laurent%20F.%22%2C%22lastName%22%3A%22Thomas%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Johanne%22%2C%22lastName%22%3A%22Tremblay%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anke%22%2C%22lastName%22%3A%22T%5Cu00f6njes%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Peter%20J.%22%2C%22lastName%22%3A%22van%20der%20Most%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Veronique%22%2C%22lastName%22%3A%22Vitart%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Uwe%22%2C%22lastName%22%3A%22V%5Cu00f6lker%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ya%20Xing%22%2C%22lastName%22%3A%22Wang%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Chaolong%22%2C%22lastName%22%3A%22Wang%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wen%20Bin%22%2C%22lastName%22%3A%22Wei%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22John%20B.%22%2C%22lastName%22%3A%22Whitfield%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Sarah%20H.%22%2C%22lastName%22%3A%22Wild%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22James%20F.%22%2C%22lastName%22%3A%22Wilson%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Thomas%20W.%22%2C%22lastName%22%3A%22Winkler%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tien-Yin%22%2C%22lastName%22%3A%22Wong%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mark%22%2C%22lastName%22%3A%22Woodward%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Xueling%22%2C%22lastName%22%3A%22Sim%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Audrey%20Y.%22%2C%22lastName%22%3A%22Chu%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mary%20F.%22%2C%22lastName%22%3A%22Feitosa%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Unnur%22%2C%22lastName%22%3A%22Thorsteinsdottir%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Adriana%20M.%22%2C%22lastName%22%3A%22Hung%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Alexander%22%2C%22lastName%22%3A%22Teumer%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Nora%22%2C%22lastName%22%3A%22Franceschini%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Afshin%22%2C%22lastName%22%3A%22Parsa%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anna%22%2C%22lastName%22%3A%22K%5Cu00f6ttgen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Pascal%22%2C%22lastName%22%3A%22Schlosser%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Cristian%22%2C%22lastName%22%3A%22Pattaro%22%7D%5D%2C%22abstractNote%22%3A%22X-chromosomal%20genetic%20variants%20are%20understudied%20but%20can%20yield%20valuable%20insights%20into%20sexually%20dimorphic%20human%20traits%20and%20diseases.%20We%20performed%20a%20sex-stratified%20cross-ancestry%20X-chromosome-wide%20association%20meta-analysis%20of%20seven%20kidney-related%20traits%20%28n%5Cu2009%3D%5Cu2009908%2C697%29%2C%20identifying%2023%20loci%20genome-wide%20significantly%20associated%20with%20two%20of%20the%20traits%3A%207%20for%20uric%20acid%20and%2016%20for%20estimated%20glomerular%20filtration%20rate%20%28eGFR%29%2C%20including%20four%20novel%20eGFR%20loci%20containing%20the%20functionally%20plausible%20prioritized%20genes%20ACSL4%2C%20CLDN2%2C%20TSPAN6%20and%20the%20female-specific%20DRP2.%20Further%2C%20we%20identified%20five%20novel%20sex-interactions%2C%20comprising%20male-specific%20effects%20at%20FAM9B%20and%20AR%5C%2FEDA2R%2C%20and%20three%20sex-differential%20findings%20with%20larger%20genetic%20effect%20sizes%20in%20males%20at%20DCAF12L1%20and%20MST4%20and%20larger%20effect%20sizes%20in%20females%20at%20HPRT1.%20All%20prioritized%20genes%20in%20loci%20showing%20significant%20sex-interactions%20were%20located%20next%20to%20androgen%20response%20elements%20%28ARE%29.%20Five%20ARE%20genes%20showed%20sex-differential%20expressions.%20This%20study%20contributes%20new%20insights%20into%20sex-dimorphisms%20of%20kidney%20traits%20along%20with%20new%20prioritized%20gene%20targets%20for%20further%20molecular%20research.%22%2C%22date%22%3A%222024-01-18%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1038%5C%2Fs41467-024-44709-1%22%2C%22ISSN%22%3A%222041-1723%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222024-06-04T05%3A32%3A43Z%22%7D%7D%2C%7B%22key%22%3A%22H5IM9KFT%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Fulfs%20et%20al.%22%2C%22parsedDate%22%3A%222024-01-05%22%2C%22numChildren%22%3A2%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EFulfs%2C%20Theresa%2C%20Tanja%20Poulain%2C%20Mandy%20Vogel%2C%20Kolja%20Nenoff%2C%20and%20Wieland%20Kiess.%20%26%23x201C%3BAssociations%20between%20Sleep%20Problems%20and%20Emotional%5C%2FBehavioural%20Difficulties%20in%20Healthy%20Children%20and%20Adolescents.%26%23x201D%3B%20%3Ci%3EBMC%20Pediatrics%3C%5C%2Fi%3E%2024%2C%20no.%201%20%28January%205%2C%202024%29%3A%2015.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs12887-023-04487-z%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs12887-023-04487-z%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Associations%20between%20sleep%20problems%20and%20emotional%5C%2Fbehavioural%20difficulties%20in%20healthy%20children%20and%20adolescents%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Theresa%22%2C%22lastName%22%3A%22Fulfs%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Kolja%22%2C%22lastName%22%3A%22Nenoff%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%5D%2C%22abstractNote%22%3A%22OBJECTIVE%3A%20This%20study%20aimed%20to%20%281%29%20characterise%20sleep%20disturbances%20and%20emotional%5C%2Fbehavioural%20difficulties%20among%20healthy%20German%20children%20and%20adolescents%20aged%203%20to%2013%5Cu00a0years%2C%20%282%29%20examine%20the%20association%20between%20parent-reported%20sleep%20problems%20and%20emotional%5C%2Fbehavioural%20difficulties%2C%20%283%29%20point%20out%20possible%20relations%20between%20specific%20kinds%20of%20sleep%20disturbances%20and%20different%20behavioural%20difficulties.%5CnMETHODS%3A%20Data%20were%20collected%20between%202011%20and%202015%20within%20the%20LIFE%20Child%20study%20in%20Germany.%20The%20sample%20included%201101%203-%20to%2013-year-old%20children%20and%20adolescents.%20Information%20on%20sleep%20disturbances-assessed%20via%20the%20Children%27s%20Sleep%20Habits%20Questionnaire%20%28CSHQ%29%2C%20emotional%5C%2Fbehavioural%20difficulties-assessed%20via%20the%20Strengths%20and%20Difficulties%20Questionnaire%20%28SDQ%29%2C%20and%20socioeconomic%20status%20was%20provided%20by%20participants%27%20parents.%20Multiple%20regressions%20were%20applied%20to%20analyse%20the%20associations%20between%20general%20and%20specific%20sleep%20disturbances%20%28independent%20variables%29%20and%20emotional%5C%2Fbehavioural%20difficulties%20%28dependent%20variables%29.%5CnRESULTS%3A%20The%20total%20CSHQ%20score%20was%20positively%20associated%20with%20the%20total%20SDQ%20score%20and%20all%20SDQ%20subscales%20%28emotional%20problems%2C%20conduct%20problems%2C%20hyperactivity%5C%2Finattention%2C%20peer%20relationship%20problems%29.%20Most%20of%20the%20CSHQ%20subscales%20were%20related%20to%20SDQ%20subscale%20scores%2C%20except%20for%20a%20few%20non-significant%20relations%20with%20hyperactivity%5C%2Finattention%20and%20conduct%20problems.%20The%20CSHQ%20total%20score%2C%20daytime%20sleepiness%2C%20sleep%20duration%20and%20parasomnias%20showed%20the%20strongest%20associations%20with%20the%20SDQ%20total%20score.%5CnCONCLUSION%3A%20This%20study%20confirms%20an%20association%20between%20children%27s%20and%20adolescents%27%20sleep%20habits%20and%20psychological%20health.%20We%20were%20able%20to%20demonstrate%20the%20association%20between%20sleep%20problems%20and%20emotional%5C%2Fbehavioural%20difficulties%20in%20a%20large%20sample%20of%20healthy%20participants.%20In%20particular%2C%20we%20observed%20a%20significant%20relation%20between%20parasomnias%20and%20hyperactive%5C%2Finattentive%20behaviour%20as%20well%20as%20a%20significant%20association%20between%20emotional%20problems%20and%20sleep%20problems%2C%20especially%20daytime%20sleepiness%2C%20sleep%20anxiety%20and%20parasomnias.%22%2C%22date%22%3A%222024-01-05%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1186%5C%2Fs12887-023-04487-z%22%2C%22ISSN%22%3A%221471-2431%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222024-03-06T09%3A11%3A53Z%22%7D%7D%2C%7B%22key%22%3A%22HHMBIJDL%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Wilpert%20et%20al.%22%2C%22parsedDate%22%3A%222024-01%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EWilpert%2C%20Nina-Maria%2C%20Roma%20Thamm%2C%20Michael%20Thamm%2C%20J%26%23xFC%3Brgen%20Kratzsch%2C%20Dominik%20Seelow%2C%20Mandy%20Vogel%2C%20Heiko%20Krude%2C%20and%20Markus%20Schuelke.%20%26%23x201C%3BNormal%20Values%20for%20the%20FT3%5C%2FFT4%20Ratio%3A%20Centile%20Charts%20%280%26%23×2013%3B29%20Years%29%20and%20Their%20Application%20for%20the%20Differential%20Diagnosis%20of%20Children%20with%20Developmental%20Delay.%26%23x201D%3B%20%3Ci%3EInternational%20Journal%20of%20Molecular%20Sciences%3C%5C%2Fi%3E%2025%2C%20no.%2016%20%28January%202024%29%3A%208585.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Fijms25168585%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Fijms25168585%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Normal%20Values%20for%20the%20fT3%5C%2FfT4%20Ratio%3A%20Centile%20Charts%20%280%5Cu201329%20Years%29%20and%20Their%20Application%20for%20the%20Differential%20Diagnosis%20of%20Children%20with%20Developmental%20Delay%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Nina-Maria%22%2C%22lastName%22%3A%22Wilpert%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Roma%22%2C%22lastName%22%3A%22Thamm%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Michael%22%2C%22lastName%22%3A%22Thamm%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J%5Cu00fcrgen%22%2C%22lastName%22%3A%22Kratzsch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Dominik%22%2C%22lastName%22%3A%22Seelow%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Heiko%22%2C%22lastName%22%3A%22Krude%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Markus%22%2C%22lastName%22%3A%22Schuelke%22%7D%5D%2C%22abstractNote%22%3A%22Primary%20congenital%20hypothyroidism%20is%20easily%20diagnosed%20on%20the%20basis%20of%20elevated%20plasma%20levels%20of%20thyroid-stimulating%20hormone%20%28TSH%29.%20In%20contrast%2C%20in%20the%20rare%20disorders%20of%20thyroid%20hormone%20resistance%2C%20TSH%20and%2C%20in%20mild%20cases%2C%20also%20thyroid%20hormone%20levels%20are%20within%20the%20normal%20range.%20Thyroid%20hormone%20resistance%20is%20caused%20by%20defects%20in%20hormone%20metabolism%2C%20transport%2C%20or%20receptor%20activation%20and%20can%20have%20the%20same%20serious%20consequences%20for%20child%20development%20as%20congenital%20hypothyroidism.%20A%20total%20of%20n%20%3D%2023%2C522%20data%20points%20from%20a%20large%20cohort%20of%20children%20and%20young%20adults%20were%20used%20to%20generate%20normal%20values%20and%20sex-specific%20percentiles%20for%20the%20ratio%20of%20free%20triiodothyronine%20%28T3%29%20to%20free%20thyroxine%20%28T4%29%2C%20the%20fT3%5C%2FfT4%20ratio.%20The%20aim%20was%20to%20determine%20whether%20individuals%20with%20developmental%20delay%20and%20genetically%20confirmed%20thyroid%20hormone%20resistance%2C%20carrying%20defects%20in%20Monocarboxylate%20Transporter%208%20%28MCT8%29%2C%20Thyroid%20Hormone%20Receptor%20alpha%20%28THR%5Cu03b1%29%2C%20and%20Selenocysteine%20Insertion%20Sequence-Binding%20Protein%202%20%28SECISBP2%29%2C%20had%20abnormal%20fT3%5C%2FfT4%20ratios.%20Indeed%2C%20we%20were%20able%20to%20demonstrate%20a%20clear%20separation%20of%20patient%20values%20for%20the%20fT3%5C%2FfT4%20ratio%20from%20normal%20and%20pathological%20controls%20%28e.g.%2C%20children%20with%20severe%20cerebral%20palsy%29.%20We%20therefore%20recommend%20using%20the%20fT3%5C%2FfT4%20ratio%20as%20a%20readily%20available%20screening%20parameter%20in%20children%20with%20developmental%20delay%20for%20the%20identification%20of%20thyroid%20hormone%20resistance%20syndromes.%20The%20fT3%5C%2FfT4%20ratio%20can%20be%20easily%20plotted%20on%20centile%20charts%20using%20our%20free%20online%20tool%2C%20which%20accepts%20various%20SI%20and%20non-SI%20units%20for%20fT3%2C%20fT4%2C%20and%20TSH.%22%2C%22date%22%3A%222024%5C%2F1%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.3390%5C%2Fijms25168585%22%2C%22ISSN%22%3A%221422-0067%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.mdpi.com%5C%2F1422-0067%5C%2F25%5C%2F16%5C%2F8585%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222024-08-13T15%3A36%3A37Z%22%7D%7D%2C%7B%22key%22%3A%22V6UXU4V3%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Ridefelt%20et%20al.%22%2C%22parsedDate%22%3A%222024%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3ERidefelt%2C%20Peter%2C%20Johan%20Saldeen%2C%20Mandy%20Vogel%2C%20Uta%20Ceglarek%2C%20Wieland%20Kiess%2C%20and%20Anders%20Larsson.%20%26%23x201C%3BPediatric%20Reference%20Intervals%20for%20Serum%20Folate%20and%20Cobalamin%20Based%20on%20a%20European%20Population%20without%20Exposure%20to%20Folic%20Acid%20Fortification.%26%23x201D%3B%20%3Ci%3EScandinavian%20Journal%20of%20Clinical%20and%20Laboratory%20Investigation%3C%5C%2Fi%3E%20online%20ahead%20of%20print%2C%20no.%200%20%282024%29%3A%201%26%23×2013%3B5.%20%3Ca%20class%3D%27zp-ItemURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1080%5C%2F00365513.2024.2330918%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1080%5C%2F00365513.2024.2330918%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Pediatric%20reference%20intervals%20for%20serum%20folate%20and%20cobalamin%20based%20on%20a%20European%20population%20without%20exposure%20to%20folic%20acid%20fortification%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Peter%22%2C%22lastName%22%3A%22Ridefelt%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Johan%22%2C%22lastName%22%3A%22Saldeen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Uta%22%2C%22lastName%22%3A%22Ceglarek%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anders%22%2C%22lastName%22%3A%22Larsson%22%7D%5D%2C%22abstractNote%22%3A%22The%20aim%20of%20the%20present%20study%20was%20to%20define%20pediatric%20reference%20intervals%20for%20serum%20cobalamin%20and%20folate%20utilizing%20data%20generated%20from%20a%20population%20not%20exposed%20to%20food%20fortified%20with%20folic%20acid.%20Folate%20and%20cobalamin%20results%20analyzed%20by%20electrochemiluminescence%20immunoassay%20%28Roche%20Cobas%29%20were%20obtained%20from%202375%20children%20%282%20months%20to%2017.99%20years%20of%20age%29.%20The%20serum%20samples%20were%20collected%20between%202011%20and%202015%20as%20part%20of%20the%20LIFE%20%28Leipzig%20Research%20Centre%20for%20Civilization%20Diseases%29%20Child%20cohort%20study%20in%20Germany%2C%20where%20folic%20acid%20fortification%20of%20food%20is%20not%20mandated.%20These%20results%20were%20used%20to%20generate%20age-%20and%20gender-specific%20reference%20intervals%20presented%20as%20non-parametric%202.5%20and%2097.5%20percentiles.%20Because%20of%20a%20subsequent%20restandardisation%20of%20the%20Roche%20folate%20assay%20in%202016%2C%20folate%20values%20were%20recalculated%20accordingly%20for%20adaptation%20to%20results%20obtained%20using%20the%20present%20calibration.%20In%20both%20genders%2C%20folate%20concentrations%20decreased%20continuously%20with%20age%2C%20whereas%20cobalamin%20concentrations%20peaked%20at%20five%20years%20of%20age%20and%20then%20declined.%20Teenage%20females%20had%20higher%20concentrations%20of%20cobalamin%20in%20the%20age%20group%2012%5Cu201317.99%20years.%22%2C%22date%22%3A%222024%22%2C%22language%22%3A%22%22%2C%22DOI%22%3A%2210.1080%5C%2F00365513.2024.2330918%22%2C%22ISSN%22%3A%220036-5513%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1080%5C%2F00365513.2024.2330918%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222024-08-27T12%3A39%3A37Z%22%7D%7D%2C%7B%22key%22%3A%22A8SXRF42%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Petri%20et%20al.%22%2C%22parsedDate%22%3A%222024%22%2C%22numChildren%22%3A2%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EPetri%2C%20Laura%2C%20Tanja%20Poulain%2C%20Mandy%20Vogel%2C%20Christof%20Meigen%2C%20Wieland%20Kiess%2C%20and%20Andreas%20Hiemisch.%20%26%23x201C%3BParent-Perceived%20Recurrent%20Pain%20in%20Children%3A%20Associations%20with%20Maternal%20Pain%2C%20Depressiveness%2C%20Socioeconomic%20Status%2C%20and%20Children%26%23×2019%3Bs%20Behavioural%20Difficulties.%26%23x201D%3B%20%3Ci%3EFrontiers%20in%20Pediatrics%3C%5C%2Fi%3E%2012%20%282024%29%3A%201287343.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3389%5C%2Ffped.2024.1287343%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3389%5C%2Ffped.2024.1287343%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Parent-perceived%20recurrent%20pain%20in%20children%3A%20associations%20with%20maternal%20pain%2C%20depressiveness%2C%20socioeconomic%20status%2C%20and%20children%27s%20behavioural%20difficulties%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Laura%22%2C%22lastName%22%3A%22Petri%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christof%22%2C%22lastName%22%3A%22Meigen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andreas%22%2C%22lastName%22%3A%22Hiemisch%22%7D%5D%2C%22abstractNote%22%3A%22OBJECTIVES%3A%20The%20current%20study%20aimed%20to%20examine%20the%20potential%20transgenerational%20associations%20between%20maternal%20pain%20and%20depressiveness%20and%20childhood%20pain%2C%20and%20to%20explore%20the%20associations%20between%20the%20children%27s%20difficulties%20and%20recurrent%20pain%20%28defined%20as%20pain%20occurring%20at%20least%20once%20a%20month%20in%20the%20previous%206%20month%29%20in%20healthy%20children%20aged%203-13%20years.%5CnMETHODS%3A%20We%20collected%20Data%20between%202015%20and%202019%20as%20part%20of%20the%20LIFE%20Child%20study%20in%20Germany%20and%20investigated%20associations%20of%20maternal%20pain%20and%20depressiveness%2C%20child%20age%2C%20sex%2C%20pubertal%20stage%2C%20emotional%20difficulties%2C%20conduct%20difficulties%2C%20hyperactivity%5C%2Finattention%2C%20peer%20group%20difficulties%2C%20and%20prosocial%20skills%2C%20and%20family%20socioeconomic%20status%20with%20the%20frequency%20of%20parent-perceived%20headache%2C%20backache%2C%20and%20stomachache%20in%20a%20sample%20of%201%2C850%20children%20%284%2C819%20documented%20visits%29%20using%20logistic%20and%20ordinal%20regression%20analyses.%5CnRESULTS%3A%20Overall%2C%2010.4%25%2C%2024.4%25%2C%20and%2045.2%25%20of%20parents%20reported%20their%20children%20had%20recurrent%20backache%2C%20headache%2C%20and%20stomachache%2C%20respectively%2C%20with%205.5%25%20of%20children%20were%20reported%20to%20experience%20all%20three%20types%20of%20pain%20simultaneously.%20Higher%20age%2C%20female%20sex%2C%20puberty%2C%20emotional%20difficulties%2C%20low%20family%20socioeconomic%20status%2C%20as%20well%20as%20higher%20maternal%20impairment%20due%20to%20pain%20and%20maternal%20depressiveness%20were%20significantly%20associated%20with%20more%20frequent%20pain.%5CnCONCLUSIONS%3A%20Our%20study%20suggests%20that%20maternal%20pain%2C%20maternal%20depressiveness%2C%20and%20lower%20family%20socioeconomic%20status%20as%20well%20as%20child%27s%20emotional%20difficulties%20are%20significantly%20associated%20with%20a%20higher%20frequency%20of%20recurrent%20pain%20in%20children%20perceived%20by%20their%20parents.%22%2C%22date%22%3A%222024%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.3389%5C%2Ffped.2024.1287343%22%2C%22ISSN%22%3A%222296-2360%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222024-08-27T12%3A40%3A19Z%22%7D%7D%2C%7B%22key%22%3A%22D3U7X6PF%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Gr%5Cu00fcning%20Parache%20et%20al.%22%2C%22parsedDate%22%3A%222023-12-26%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EGr%26%23xFC%3Bning%20Parache%2C%20Laura%2C%20Mandy%20Vogel%2C%20Christof%20Meigen%2C%20Wieland%20Kiess%2C%20and%20Tanja%20Poulain.%20%26%23x201C%3BFamily%20Structure%2C%20Socioeconomic%20Status%2C%20and%20Mental%20Health%20in%20Childhood.%26%23x201D%3B%20%3Ci%3EEuropean%20Child%20%26amp%3B%20Adolescent%20Psychiatry%3C%5C%2Fi%3E%2C%20December%2026%2C%202023.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs00787-023-02329-y%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs00787-023-02329-y%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Family%20structure%2C%20socioeconomic%20status%2C%20and%20mental%20health%20in%20childhood%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Laura%22%2C%22lastName%22%3A%22Gr%5Cu00fcning%20Parache%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christof%22%2C%22lastName%22%3A%22Meigen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%5D%2C%22abstractNote%22%3A%22The%20changing%20landscape%20of%20family%20structures%20over%20the%20last%20decades%20has%20led%20to%20a%20growing%20need%20to%20investigate%20its%20impact%20on%20children%27s%20well-being.%20This%20study%20examined%20differences%20in%20mental%20health%20among%20children%20from%20different%20family%20compositions%20and%20how%20these%20differences%20may%20be%20affected%20by%20familial%20socioeconomic%20status%20%28SES%29.%20Data%20were%20collected%20within%20the%20LIFE%20Child%20study.%20Participants%20included%202828%20children%20aged%203-17%5Cu00a0years%20raised%20in%20traditional%20families%2C%20stepfamilies%2C%20or%20single-parent%20families.%20Mental%20health%20was%20measured%20using%20the%20Strengths%20and%20Difficulties%20Questionnaire%20%28SDQ%20%28behavioral%20strengths%20and%20difficulties%29%29%20and%20the%20KIDSCREEN-27%20questionnaire%20%28quality%20of%20life%29.%20Linear%20regression%20analyses%20were%20applied%20to%20examine%20associations%20between%20family%20structure%2C%20SES%2C%20and%20mental%20health%20outcomes.%20Children%20from%20single-parent%20families%20exhibited%20worse%20mental%20health%20outcomes%20than%20those%20from%20traditional%20families%20across%20all%20domains%20of%20the%20SDQ%20and%20the%20KIDSCREEN-27.%20Children%20from%20stepfamilies%20showed%20significantly%20higher%20Total%20Difficulties%20scores%20%28B%5Cu2009%3D%5Cu20091.29%20and%201.42%29%2C%20with%203-%20to%2010-year-olds%20displaying%20higher%20scores%20in%20the%20Hyperactivity%20%26%20Inattention%20%28B%5Cu2009%3D%5Cu20090.61%29%20and%20Peer%20Relationship%20Problems%20%28B%5Cu2009%3D%5Cu20090.36%29%20subscales%2C%20and%2011-%20to%2017-year-olds%20showing%20higher%20Conduct%20Problems%20%28B%5Cu2009%3D%5Cu20090.31%29%2C%20Emotional%20Symptoms%20%28B%5Cu2009%3D%5Cu20090.58%29%2C%20and%20a%20worse%20Parent%20Relationship%20scores%20%28B%5Cu2009%3D%5Cu2009-%5Cu00a01.82%29%20than%20children%20from%20traditional%20families%20%28all%20p%5Cu2009%3C%5Cu20090.05%29.%20After%20controlling%20for%20SES%2C%20several%20associations%20between%20family%20structure%20and%20mental%20health%20lost%20significance%2C%20while%20others%20persisted%2C%20particularly%20among%20older%20children.%20To%20promote%20mental%20health%20in%20non-traditional%20families%2C%20interventions%20should%20address%20socioeconomic%20disparities%20while%20also%20investigating%20factors%20contributing%20to%20the%20direct%20impact%20of%20family%20structure%20on%20mental%20well-being.Trial%20registration%20The%20LIFE%20Child%20study%20is%20registered%20on%20clinicaltrials.gov%20%28No.%20NCT02550236%29.%22%2C%22date%22%3A%222023-12-26%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1007%5C%2Fs00787-023-02329-y%22%2C%22ISSN%22%3A%221435-165X%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-12-28T07%3A09%3A36Z%22%7D%7D%2C%7B%22key%22%3A%22R5N3S77M%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Harings%20et%20al.%22%2C%22parsedDate%22%3A%222023-11-29%22%2C%22numChildren%22%3A2%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EHarings%2C%20Tanjana%2C%20Martina%20Patrizia%20Neininger%2C%20Simone%20Eisenhofer%2C%20Alena%20Gerlinde%20Thiele%2C%20Wieland%20Kiess%2C%20Astrid%20Bertsche%2C%20Skadi%20Beblo%2C%20and%20Thilo%20Bertsche.%20%26%23x201C%3BParents%26%23×2019%3B%20Perceptions%20Regarding%20Their%20Children%26%23×2019%3Bs%20Medications%20and%20Expert-Assessed%20Drug-Related%20Problems%20in%20Pediatric%20Patients%20with%20Inborn%20Errors%20of%20Metabolism.%26%23x201D%3B%20%3Ci%3EChildren%20%28Basel%2C%20Switzerland%29%3C%5C%2Fi%3E%2010%2C%20no.%2012%20%28November%2029%2C%202023%29%3A%201873.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Fchildren10121873%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Fchildren10121873%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Parents%27%20Perceptions%20Regarding%20Their%20Children%27s%20Medications%20and%20Expert-Assessed%20Drug-Related%20Problems%20in%20Pediatric%20Patients%20with%20Inborn%20Errors%20of%20Metabolism%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanjana%22%2C%22lastName%22%3A%22Harings%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Martina%20Patrizia%22%2C%22lastName%22%3A%22Neininger%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Simone%22%2C%22lastName%22%3A%22Eisenhofer%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Alena%20Gerlinde%22%2C%22lastName%22%3A%22Thiele%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Astrid%22%2C%22lastName%22%3A%22Bertsche%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Skadi%22%2C%22lastName%22%3A%22Beblo%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Thilo%22%2C%22lastName%22%3A%22Bertsche%22%7D%5D%2C%22abstractNote%22%3A%22We%20aimed%20to%20explore%20parents%27%20perceptions%20of%20their%20children%27s%20medication%20use%20for%20inborn%20errors%20of%20metabolism%20%28IEM%29%2C%20including%20the%20importance%20of%20medication%20intake%2C%20potential%20complications%2C%20and%20concerns%20about%20adverse%20drug%20reactions%20%28ADR%29.%20Additionally%2C%20we%20aimed%20to%20determine%20expert-assessed%20clinically%20relevant%20drug-related%20problems%2C%20particularly%20those%20attributable%20to%20IEM.%20We%20interviewed%20108%20parents%20of%20119%20pediatric%20patients%20with%20IEM%20using%20a%20questionnaire%20relating%20to%20their%20perceptions%20regarding%20their%20children%27s%20IEM%20medication.%20In%20affected%20siblings%2C%20a%20questionnaire%20was%20used%20for%20each%20child.%20We%20performed%20medication%20analyses%20to%20evaluate%20the%20patient%27s%20complete%20medication%20regimen%20for%20clinically%20relevant%20drug-related%20problems%2C%20including%20medication%20for%20conditions%20other%20than%20IEM.%20It%20was%20very%20important%20to%20the%20parents%20of%2085%25%20of%20the%20patients%20to%20use%20IEM%20medication%20exactly%20as%20prescribed.%20The%20parents%20of%2041%25%20of%20patients%20perceived%20complications%20in%20their%20children%27s%20use%20of%20IEM%20medication.%20The%20parents%20of%2047%25%20of%20patients%20reported%20fears%20concerning%20ADR%20because%20of%20IEM%20medication.%20Parents%20observed%20ADR%20in%2027%25%20of%20patients%20because%20of%20IEM%20medication.%20In%2044%25%20of%20patients%2C%20medication%20for%20conditions%20other%20than%20IEM%20was%20inadequate%20because%20of%20drug-related%20problems%20not%20associated%20with%20the%20IEM%3B%20a%20safe%20alternative%20existed%20in%2021%25%20of%20patients.%20In%20summary%2C%20almost%20half%20of%20the%20parents%20of%20patients%20with%20IEM%20reported%20complications%20with%20their%20child%27s%20IEM%20medication%20intake%20and%20fears%20of%20ADR.%20Medication%20analyses%20showed%20that%20drug-related%20problems%20occurred%20regardless%20of%20IEM%2C%20emphasizing%20the%20general%20need%20to%20prescribe%20and%20dispense%20adequate%2C%20child-appropriate%20medication%20to%20minimize%20clinically%20relevant%20drug-related%20problems%20in%20pediatric%20patients.%22%2C%22date%22%3A%222023-11-29%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.3390%5C%2Fchildren10121873%22%2C%22ISSN%22%3A%222227-9067%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222024-03-06T09%3A11%3A02Z%22%7D%7D%2C%7B%22key%22%3A%22EFN9XGX2%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22lastModifiedByUser%22%3A%7B%22id%22%3A1995470%2C%22username%22%3A%22mvogel78%22%2C%22name%22%3A%22%22%2C%22links%22%3A%7B%22alternate%22%3A%7B%22href%22%3A%22https%3A%5C%2F%5C%2Fwww.zotero.org%5C%2Fmvogel78%22%2C%22type%22%3A%22text%5C%2Fhtml%22%7D%7D%7D%2C%22creatorSummary%22%3A%22Krause%20et%20al.%22%2C%22parsedDate%22%3A%222023-11-23%22%2C%22numChildren%22%3A3%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EKrause%2C%20Lea%2C%20Tanja%20Poulain%2C%20Wieland%20Kiess%2C%20and%20Mandy%20Vogel.%20%26%23x201C%3BBody%20Image%20and%20Behavioural%20and%20Emotional%20Difficulties%20in%20German%20Children%20and%20Adolescents.%26%23x201D%3B%20%3Ci%3EBMC%20Pediatrics%3C%5C%2Fi%3E%2023%2C%20no.%201%20%28November%2023%2C%202023%29%3A%20594.%20%3Ca%20class%3D%27zp-ItemURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs12887-023-04405-3%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs12887-023-04405-3%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Body%20image%20and%20behavioural%20and%20emotional%20difficulties%20in%20German%20children%20and%20adolescents%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Lea%22%2C%22lastName%22%3A%22Krause%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%5D%2C%22abstractNote%22%3A%22Behavioural%20and%20emotional%20difficulties%20might%20play%20an%20important%20role%20in%20the%20development%20of%20body%20image%20disturbances%2C%20which%20represent%20serious%20risk%20factors%20for%20eating%20disorders%20or%20depression.%20The%20present%20study%20provides%20a%20detailed%20overview%20on%20body%20image%20disturbances%20and%20several%20behavioural%20and%20emotional%20difficulties%20%28differences%20between%20gender%2C%20age%2C%20and%20weight%20status%29%20and%20their%20inter-relations%20in%20German%20children%20and%20adolescents.%22%2C%22date%22%3A%222023-11-23%22%2C%22language%22%3A%22%22%2C%22DOI%22%3A%2210.1186%5C%2Fs12887-023-04405-3%22%2C%22ISSN%22%3A%221471-2431%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs12887-023-04405-3%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222024-08-27T10%3A18%3A31Z%22%7D%7D%2C%7B%22key%22%3A%22Q8BWZ4IW%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Bier%20et%20al.%22%2C%22parsedDate%22%3A%222023-11%22%2C%22numChildren%22%3A2%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EBier%2C%20Elisabeth%2C%20Mandy%20Vogel%2C%20Nico%20Grafe%2C%20Anne%20Jurkutat%2C%20Juliane%20Ludwig%2C%20Oleg%20Wagner%2C%20Christof%20Meigen%2C%20Wieland%20Kiess%2C%20and%20Tanja%20Poulain.%20%26%23x201C%3BChildren%26%23×2019%3Bs%20Satisfaction%20with%20a%20Comprehensive%20Study%20Program-Results%20from%20the%20LIFE%20Child%20Cohort%20Study.%26%23x201D%3B%20%3Ci%3EPaediatric%20and%20Perinatal%20Epidemiology%3C%5C%2Fi%3E%2037%2C%20no.%208%20%28November%202023%29%3A%20704%26%23×2013%3B9.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fppe.13007%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fppe.13007%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Children%27s%20satisfaction%20with%20a%20comprehensive%20study%20program-Results%20from%20the%20LIFE%20Child%20cohort%20study%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Elisabeth%22%2C%22lastName%22%3A%22Bier%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Nico%22%2C%22lastName%22%3A%22Grafe%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anne%22%2C%22lastName%22%3A%22Jurkutat%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Juliane%22%2C%22lastName%22%3A%22Ludwig%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Oleg%22%2C%22lastName%22%3A%22Wagner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christof%22%2C%22lastName%22%3A%22Meigen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%5D%2C%22abstractNote%22%3A%22BACKGROUND%3A%20Research%20participants%27%20satisfaction%20is%20a%20topic%20of%20great%20interest%2C%20especially%20in%20the%20context%20of%20longitudinal%20studies.%20Evaluation%20also%20represents%20an%20important%20component%20of%20quality%20management%20in%20the%20health%20care%20system.%20Adult%20studies%20found%20that%20personal%20characteristics%2C%20e.g.%2C%20age%2C%20sex%2C%20ethnicity%2C%20and%20SES%2C%20can%20influence%20satisfaction%20with%20health%20care%20or%20study%20participation.%20Studies%20on%20paediatric%20participants%20are%20sparse.%5CnOBJECTIVES%3A%20To%20examine%20how%20children%20rated%20the%20study%20day%20of%20a%20cohort%20study%20and%20how%20these%20ratings%20were%20associated%20with%20sociodemographic%20and%20socioeconomic%20characteristics%20and%20retention%20in%20the%20context%20of%20a%20large%20cohort%20study.%5CnMETHODS%3A%20Analyses%20were%20performed%20on%204-%20to%2017-year-old%20participants%20of%20the%20German%20longitudinal%20cohort%20study%20LIFE%20Child%20%28n%5Cu2009%3D%5Cu20092033%29.%20To%20assess%20the%20associations%20between%20overall%20satisfaction%20%28high%20versus%20low%5C%2Fmiddle%29%20and%20age%2C%20sex%2C%20body-mass%20index%2C%20socioecomonic%20status%2C%20and%20participation%20in%20a%20follow-up%20visit%2C%20we%20applied%20logistic%20mixed-effects%20models.%5CnRESULTS%3A%20Participants%27%20overall%20satisfaction%20with%20the%20LIFE%20Child%20study%20day%20was%20high%20%28%5C%22very%20good%5C%22%3A%2067.8%25%29.%20Overall%20satisfaction%20was%20higher%20in%207-9%5Cu2009years%20olds%20%28odds%20ratio%20%5BOR%5D%202.00%2C%2095%25%20confidence%20interval%20%5BCI%201.51%2C%202.66%29%20and%2010-12%5Cu2009years%20olds%20%28OR%201.51%2C%2095%25%20CI%201.16%2C%201.98%29%20than%20in%204-6%5Cu2009years%20olds%20and%2013-17%20years%20olds.%20Children%20with%20obesity%20were%20less%20likely%20to%20participate%20in%20a%20follow-up%20visit%20%28OR%200.56%2C%2095%25%20CI%200.39%2C%200.78%29.%20Children%20reporting%20high%20overall%20satisfaction%20at%20the%20first%20study%20visit%20completed%20a%20follow-up%20visit%20more%20frequently%20%28OR%201.32%2C%2095%25%20CI%201.05%2C1.67%29.%5CnCONCLUSIONS%3A%20A%20high%20level%20of%20satisfaction%20increased%20participants%27%20attendance%20at%20a%20follow-up%20visit.%20Our%20results%20might%20be%20helpful%20for%20adapting%20the%20study%20program%20to%20the%20participants%27%20needs%20in%20order%20to%20maximise%20retention%20and%20minimise%20attrition%20rates.%22%2C%22date%22%3A%222023-11%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1111%5C%2Fppe.13007%22%2C%22ISSN%22%3A%221365-3016%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222024-08-13T12%3A49%3A47Z%22%7D%7D%2C%7B%22key%22%3A%22XMRHA647%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Kiess%20et%20al.%22%2C%22parsedDate%22%3A%222023-10-01%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EKiess%2C%20Alexandra%2C%20Jessica%20Green%2C%20Anja%20Willenberg%2C%20Uta%20Ceglarek%2C%20Ingo%20D%26%23xE4%3Bhnert%2C%20Wieland%20Kiess%2C%20and%20Mandy%20Vogel.%20%26%23x201C%3BInfluence%20of%20Growth%20and%20Metabolic%20Markers%20on%20Hs-Troponin%20T%20and%20NT-ProBNP%20Levels%20in%20Healthy%20Children.%26%23x201D%3B%20%3Ci%3EEndocrine%20Connections%3C%5C%2Fi%3E%2012%2C%20no.%2010%20%28October%201%2C%202023%29.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1530%5C%2FEC-23-0120%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1530%5C%2FEC-23-0120%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Influence%20of%20growth%20and%20metabolic%20markers%20on%20hs-troponin%20T%20and%20NT-proBNP%20levels%20in%20healthy%20children%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Alexandra%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jessica%22%2C%22lastName%22%3A%22Green%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anja%22%2C%22lastName%22%3A%22Willenberg%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Uta%22%2C%22lastName%22%3A%22Ceglarek%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ingo%22%2C%22lastName%22%3A%22D%5Cu00e4hnert%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%5D%2C%22abstractNote%22%3A%22Background%20and%20objectives%20As%20part%20of%20the%20LIFE%20Child%20study%2C%20we%20previously%20described%20the%20associations%20between%20N-terminal-pro-hormone%20brain%20natriuretic%20peptide%20%28NT-proBNP%29%20and%20hs-troponin%20T%20%28hs-TnT%29%20levels%20and%20an%20individual%5Cu2019s%20sex%2C%20age%20and%20pubertal%20status%2C%20as%20well%20as%20with%20body%20mass%20index%20%28BMI%29%20and%20serum%20lipid%20levels.%20For%20NT-proBNP%2C%20we%20found%20inverse%20associations%20with%20advancing%20puberty%2C%20increasing%20BMI%20and%20serum%20lipid%20levels.%20These%20findings%20led%20us%20to%20further%20question%20the%20putative%20influences%20of%20the%20developing%20individual%5Cu2019s%20metabolic%20and%20growth%20status%20as%20represented%20by%20levels%20of%20insulin-like%20growth%20factor-1%20%28IGF-1%29%20and%20IGF-1-binding%20protein-3%20%28IGF-BP3%29%20as%20well%20as%20hemoglobin%20A1c%20%28HbA1c%29%20and%20Cystatin%20C%20%28CysC%29.%20Material%20and%20methods%20Serum%20values%2C%20medical%20history%20and%20anthropometric%20data%20provided%20by%202522%20children%20aged%200.25%5Cu201318%20years%20were%20collected%20and%20analyzed%20as%20per%20study%20protocol.%20Results%20A%20strong%20negative%20association%20between%20NT-proBNP%20values%20and%20IGF-1%2C%20IGF-BP3%20and%20HbA1c%20levels%20was%20identified.%20For%20IGF-BP3%2C%20this%20interaction%20was%20modulated%20by%20sex%20and%20age%2C%20for%20HbA1c%20only%20by%20age.%20For%20hs-TnT%2C%20a%20positive%20association%20was%20found%20with%20IGF-BP3%2C%20IGF-1%20and%20CysC.%20The%20association%20between%20hs-TnT%20and%20IGF-1%20was%20sex%20dependent.%20The%20association%20between%20CysC%20and%20hs-TnT%20was%20stronger%20in%20girls%2C%20but%20the%20interaction%20with%20age%20was%20only%20seen%20in%20boys.%20Between%20hs-TnT%20and%20HbA1c%2C%20the%20association%20was%20significantly%20negative%20and%20modulated%20by%20age.%20Conclusion%20Based%20on%20our%20large%20pediatric%20cohort%2C%20we%20could%20identify%20age-%20and%20sex-dependent%20interactions%20between%20the%20metabolic%20status%20represented%20by%20IGF-1%2C%20IGF-BP3%2C%20CysC%20and%20HbA1c%20levels%20and%20the%20cardiac%20markers%20NT-proBNP%20and%20hs-TnT.%22%2C%22date%22%3A%222023%5C%2F10%5C%2F01%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1530%5C%2FEC-23-0120%22%2C%22ISSN%22%3A%222049-3614%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fec.bioscientifica.com%5C%2Fview%5C%2Fjournals%5C%2Fec%5C%2F12%5C%2F10%5C%2FEC-23-0120.xml%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-12-29T14%3A41%3A37Z%22%7D%7D%2C%7B%22key%22%3A%22FU7YHBMQ%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Stein%20et%20al.%22%2C%22parsedDate%22%3A%222023-10-01%22%2C%22numChildren%22%3A2%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EStein%2C%20Robert%2C%20Eric%20G%26%23xF6%3Bpel%2C%20Daniel%20Weghuber%2C%20Maximiliane%20Chiara%20Hammel%2C%20Mandy%20Vogel%2C%20Wieland%20Kiess%2C%20and%20Antje%20K%26%23xF6%3Brner.%20%26%23x201C%3BAre%20There%20Relevant%20Thresholds%20of%20Insulin-Independent%20Indices%20across%20the%20Lifespan%20to%20Predict%20Alterations%20in%20Glycemic%20Control%3F%26%23×2014%3BAuthors%26%23×2019%3B%20Reply.%26%23x201D%3B%20%3Ci%3EThe%20Lancet%20Regional%20Health%20-%20Europe%3C%5C%2Fi%3E%2033%20%28October%201%2C%202023%29%3A%20100734.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.lanepe.2023.100734%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.lanepe.2023.100734%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Are%20there%20relevant%20thresholds%20of%20insulin-independent%20indices%20across%20the%20lifespan%20to%20predict%20alterations%20in%20glycemic%20control%3F%5Cu2014Authors%5Cu2019%20reply%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Robert%22%2C%22lastName%22%3A%22Stein%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Eric%22%2C%22lastName%22%3A%22G%5Cu00f6pel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Daniel%22%2C%22lastName%22%3A%22Weghuber%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Maximiliane%20Chiara%22%2C%22lastName%22%3A%22Hammel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%5D%2C%22abstractNote%22%3A%22%22%2C%22date%22%3A%222023-10-01%22%2C%22language%22%3A%22%22%2C%22DOI%22%3A%2210.1016%5C%2Fj.lanepe.2023.100734%22%2C%22ISSN%22%3A%222666-7762%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.sciencedirect.com%5C%2Fscience%5C%2Farticle%5C%2Fpii%5C%2FS2666776223001539%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222024-08-27T12%3A49%3A43Z%22%7D%7D%2C%7B%22key%22%3A%2273X3SQTI%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Roth%20et%20al.%22%2C%22parsedDate%22%3A%222023-10%22%2C%22numChildren%22%3A2%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3ERoth%2C%20Christian%2C%20Franz%20Wolfgang%20Hirsch%2C%20Ina%20Sorge%2C%20Wieland%20Kiess%2C%20Anne%20Jurkutat%2C%20Maren%20Witt%2C%20Eva%20B%26%23xF6%3Bker%2C%20and%20Daniel%20Gr%26%23xE4%3Bfe.%20%26%23x201C%3BPreclinical%20Cartilage%20Changes%20of%20the%20Knee%20Joint%20in%20Adolescent%20Competitive%20Volleyball%20Players%3A%20A%20Prospective%20T2%20Mapping%20Study.%26%23x201D%3B%20%3Ci%3ERoFo%3A%20Fortschritte%20Auf%20Dem%20Gebiete%20Der%20Rontgenstrahlen%20Und%20Der%20Nuklearmedizin%3C%5C%2Fi%3E%20195%2C%20no.%2010%20%28October%202023%29%3A%20913%26%23×2013%3B23.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1055%5C%2Fa-2081-3245%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1055%5C%2Fa-2081-3245%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Preclinical%20Cartilage%20Changes%20of%20the%20Knee%20Joint%20in%20Adolescent%20Competitive%20Volleyball%20Players%3A%20A%20Prospective%20T2%20Mapping%20Study%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christian%22%2C%22lastName%22%3A%22Roth%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Franz%20Wolfgang%22%2C%22lastName%22%3A%22Hirsch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ina%22%2C%22lastName%22%3A%22Sorge%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anne%22%2C%22lastName%22%3A%22Jurkutat%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Maren%22%2C%22lastName%22%3A%22Witt%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Eva%22%2C%22lastName%22%3A%22B%5Cu00f6ker%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Daniel%22%2C%22lastName%22%3A%22Gr%5Cu00e4fe%22%7D%5D%2C%22abstractNote%22%3A%22PURPOSE%3A%20To%20investigate%20the%20potential%20effects%20of%20volleyball%20as%20a%20competitive%20sport%20in%20adolescence%20on%20the%20cartilage%20of%20knee%20joints%20using%20T2%20mapping%20in%20MRI%20and%20identification%20of%20preclinical%20cartilage%20changes.%20Volleyball%20as%20an%20impact%20sport%20often%20leads%20to%20damage%20of%20the%20knee%20joint%20cartilage%20in%20adulthood.%20As%20T2%20mapping%20is%20widely%20available%20and%20highly%20capable%20of%20detecting%20cartilage%20changes%20prior%20to%20conventional%20MRI%20sequences%2C%20such%20a%20detection%20may%20allow%20adolescent%20volleyball%20players%20to%20change%20their%20training%20regime%20before%20structural%20damage%20can%20occur%20to%20the%20cartilage%20and%20pose%20the%20risk%20of%20osteoarthritis.%5CnMATERIALS%20AND%20METHODS%3A%20Comparative%20study%20of%20the%20patellar%2C%20femoral%2C%20and%20tibial%20cartilage%20of%2060%20knee%20joints%20using%20T2%20mapping%20on%203%5Cu200aT%20MRI.%20In%20each%20case%2C%20both%20knees%20of%2015%20adolescent%20competitive%20volleyball%20athletes%20were%20compared%20with%2015%20controls.%5CnRESULTS%3A%20In%20the%20group%20of%20competitive%20athletes%2C%20more%20focal%20cartilage%20changes%20were%20detected%20in%20the%20medial%20facet%20of%20the%20patellofemoral%20cartilage%20and%20in%20the%20medial%20femoral%20condyle%20of%20the%20knee%20joint%20cartilage%20%28p%5Cu200a%3D%5Cu200a.01%20and%20p%5Cu200a%3C.05%2C%20respectively%29.%20Furthermore%2C%20the%20latter%20showed%20a%20diffused%20increase%20in%20maximal%20T2%20mapping%20values%20%28p%5Cu200a%3C.04%20right%20and%20p%5Cu200a%3D%5Cu200a.05%20left%29.%20The%20distribution%20of%20changes%20seems%20to%20further%20depend%20on%20the%20player%27s%20position.%5CnCONCLUSION%3A%20In%20adolescent%20volleyball%20players%20in%20competitive%20sports%2C%20T2%20mapping%20demonstrates%20early%20cartilage%20changes%20in%20both%20the%20patellofemoral%20and%20medial%20femoral%20cartilages.%20The%20distribution%20of%20lesions%20depends%20on%20the%20player%27s%20position.%20Since%20the%20cascade%20from%20T2%20relaxation%20time%20increase%20to%20conspicuous%20cartilage%20damage%20is%20well%20established%2C%20early%20counter-regulation%20%28e.%5Cu200ag.%2C%20adapted%20training%20profile%2C%20targeted%20physiotherapy%2C%20and%20appropriate%20muscle%20building%20training%29%20has%20the%20potential%20to%20prevent%20later%20damage.%5CnKEY%20POINTS%3A%20%5Cu00b7%20Volleyball%20as%20a%20competitive%20sport%20in%20adolescence%20leads%20to%20preclinical%20knee%20cartilage%20changes..%20%5Cu00b7%20Cartilage%20changes%20are%20both%20focal%20and%20diffuse..%20%5Cu00b7%20Jumping-intensive%20player%20positions%20seem%20to%20show%20more%20patellofemoral%20and%20running-intensive%20more%20condylar%20cartilage%20changes..%20%5Cu00b7%20Early%20detection%20of%20these%20changes%20could%20prevent%20progression%20to%20cartilage%20damage%20through%20adapted%20training..%5CnCITATION%20FORMAT%3A%20%5Cu00b7%20Roth%20C%2C%20Hirsch%20F%2C%20Sorge%20I%20et%5Cu200aal.%20Preclinical%20Cartilage%20Changes%20of%20the%20Knee%20Joint%20in%20Adolescent%20Competitive%20Volleyball%20Players%3A%20A%20Prospective%20T2%20Mapping%20Study.%20Fortschr%20R%5Cu00f6ntgenstr%202023%3B%20195%3A%20913%5Cu200a-%5Cu200a923.%22%2C%22date%22%3A%222023-10%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1055%5C%2Fa-2081-3245%22%2C%22ISSN%22%3A%221438-9010%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-12-22T17%3A25%3A55Z%22%7D%7D%2C%7B%22key%22%3A%225BPS45K7%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Dathan-Stumpf%20et%20al.%22%2C%22parsedDate%22%3A%222023-09-25%22%2C%22numChildren%22%3A2%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EDathan-Stumpf%2C%20Anne%2C%20Massimiliano%20Lia%2C%20Christof%20Meigen%2C%20Karoline%20Bornmann%2C%20Mireille%20Martin%2C%20Manuela%20A%26%23xDF%3Bmann%2C%20Wieland%20Kiess%2C%20and%20Holger%20Stepan.%20%26%23x201C%3BNovel%20Three-Dimensional%20Body%20Scan%20Anthropometry%20versus%20MR-Pelvimetry%20for%20Vaginal%20Breech%20Delivery%20Assessment.%26%23x201D%3B%20%3Ci%3EJournal%20of%20Clinical%20Medicine%3C%5C%2Fi%3E%2012%2C%20no.%2019%20%28September%2025%2C%202023%29%3A%206181.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Fjcm12196181%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Fjcm12196181%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Novel%20Three-Dimensional%20Body%20Scan%20Anthropometry%20versus%20MR-Pelvimetry%20for%20Vaginal%20Breech%20Delivery%20Assessment%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anne%22%2C%22lastName%22%3A%22Dathan-Stumpf%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Massimiliano%22%2C%22lastName%22%3A%22Lia%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christof%22%2C%22lastName%22%3A%22Meigen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Karoline%22%2C%22lastName%22%3A%22Bornmann%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mireille%22%2C%22lastName%22%3A%22Martin%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Manuela%22%2C%22lastName%22%3A%22A%5Cu00dfmann%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Holger%22%2C%22lastName%22%3A%22Stepan%22%7D%5D%2C%22abstractNote%22%3A%22In%20this%20prospective%2C%20monocentric%20study%2C%20we%20investigated%20the%20potency%20of%20a%20novel%20three-dimensional%20%283D%29%20body%20scanner%20for%20external%20pelvic%20assessment%20in%20birth%20planning%20for%20intended%20vaginal%20breech%20delivery.%20Between%20April%202021%20and%20June%202022%2C%2073%20singleton%20pregnancies%20with%20intended%20vaginal%20birth%20from%20breech%20presentation%20%28%3E36.0%20weeks%20of%20gestation%29%20were%20measured%20using%20a%20pelvimeter%20by%20Martin%2C%20a%20three-dimensional%20body%20scanner%2C%20and%20MR-pelvimetry.%20Measures%20were%20related%20to%20vaginal%20birth%20and%20intrapartum%20cesarean%20section.%20A%20total%20of%2026%20outer%20pelvic%20dimensions%20and%207%20inner%20pelvic%20measurements%20were%20determined.%20The%20rate%20of%20successful%20vaginal%20breech%20delivery%20was%2056.9%25.%20The%20AUC%20%28area%20under%20the%20curve%29%20of%20the%20obstetric%20conjugate%20%28OC%29%20measured%20by%20MRI%20for%20predicting%20the%20primary%20outcome%20was%200.62%20%28OR%200.63%3B%20p%20%3D%200.22%29%2C%20adjusted%20for%20neonatal%20birth%20weight%200.66%20%28OR%200.60%3B%20p%20%3D%200.19%29.%20Of%20the%2022%20measured%203D%20body%20scanner%20values%2C%20the%20ratio%20of%20waist%20girth%20to%20maternal%20height%20showed%20the%20best%20prediction%20%28AUC%20%3D%200.71%3B%20OR%201.27%3B%20p%20%3D%200.015%29.%20The%20best%20predictive%20pelvimeter%20value%20was%20the%20distantia%20spinarum%20with%20an%20AUC%20of%200.65%20%28OR%20%3D%200.80%29.%20The%203D%20body%20scanner%20technique%20is%20at%20least%20equal%20to%20predict%20successful%20vaginal%20breech%20delivery%20compared%20to%20MRI%20diagnostics.%20Further%20large-scale%2C%20prospective%20studies%20are%20needed%20to%20verify%20these%20results.%22%2C%22date%22%3A%222023-09-25%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.3390%5C%2Fjcm12196181%22%2C%22ISSN%22%3A%222077-0383%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-06T21%3A19%3A29Z%22%7D%7D%2C%7B%22key%22%3A%227E5I7U9A%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22lastModifiedByUser%22%3A%7B%22id%22%3A1995470%2C%22username%22%3A%22mvogel78%22%2C%22name%22%3A%22%22%2C%22links%22%3A%7B%22alternate%22%3A%7B%22href%22%3A%22https%3A%5C%2F%5C%2Fwww.zotero.org%5C%2Fmvogel78%22%2C%22type%22%3A%22text%5C%2Fhtml%22%7D%7D%7D%2C%22creatorSummary%22%3A%22Kappelt%20et%20al.%22%2C%22parsedDate%22%3A%222023-09-22%22%2C%22numChildren%22%3A2%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EKappelt%2C%20Jonas%2C%20Christof%20Meigen%2C%20Clara%20Elise%20Schild%2C%20Wieland%20Kiess%2C%20and%20Tanja%20Poulain.%20%26%23x201C%3BEarly%20Child%20Development%20and%20Its%20Determinants%3A%20Findings%20from%20a%20Large%20Cohort%20of%20Healthy%20Children%20Growing%20up%20in%20a%20Low-Risk%20Environment.%26%23x201D%3B%20%3Ci%3EChild%3A%20Care%2C%20Health%20and%20Development%3C%5C%2Fi%3E%20n%5C%2Fa%2C%20no.%20n%5C%2Fa%20%28September%2022%2C%202023%29.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fcch.13177%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fcch.13177%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Early%20child%20development%20and%20its%20determinants%3A%20Findings%20from%20a%20large%20cohort%20of%20healthy%20children%20growing%20up%20in%20a%20low-risk%20environment%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jonas%22%2C%22lastName%22%3A%22Kappelt%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christof%22%2C%22lastName%22%3A%22Meigen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Clara%20Elise%22%2C%22lastName%22%3A%22Schild%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%5D%2C%22abstractNote%22%3A%22Background%20Despite%20numerous%20studies%20on%20early%20child%20development%2C%20there%20is%20still%20much%20to%20be%20discovered%20about%20the%20significance%20of%20possible%20risk%20factors.%20This%20study%20examines%20cognitive%2C%20motor%2C%20and%20language%20development%20of%20healthy%20children%20growing%20up%20in%20a%20low-risk%20environment%20and%20how%20various%20individual%20and%20environmental%20factors%20are%20associated%20with%20it.%20The%20study%20also%20considers%20whether%20the%20importance%20of%20particular%20parameters%20changes%20depending%20on%20child%20age.%20Methods%20Within%20the%20framework%20of%20the%20LIFE%20Child%20study%20in%20Leipzig%2C%20Germany%2C%20481%20children%20participated%20in%20a%20total%20of%20832%20visits%20between%201%20and%2036%20months%20of%20age.%20Developmental%20status%20was%20assessed%20using%20the%20Third%20Edition%20of%20the%20Bayley%20Scales%20of%20Infant%20and%20Toddler%20Development.%20Linear%20regression%20analyses%20were%20applied%20to%20examine%20the%20associations%20between%20child%20development%20and%20sex%2C%20gestational%20age%2C%20birth%20weight%2C%20birth%20mode%2C%20overweight%2C%20height%2C%20and%20parental%20education.%20Results%20Mean%20Bayley%20composite%20scores%20for%20cognitive%2C%20language%2C%20and%20motor%20development%20were%20close%20to%20the%20standard%20value%20of%20100.%20Poorer%20developmental%20outcomes%20were%20significantly%20associated%20with%20lower%20gestational%20age%2C%20vacuum%20cup%5C%2Fforceps%20birth%2C%20being%20overweight%2C%20small%20height%2C%20and%20lower%20parental%20education%2C%20although%20some%20of%20the%20associations%20became%20insignificant%20after%20applying%20multivariate%20models.%20While%20the%20association%20between%20gestational%20age%20and%20language%20development%20became%20weaker%20with%20advancing%20age%2C%20our%20interaction%20models%20found%20disparities%20related%20to%20parental%20education%20to%20become%20more%20apparent%20in%20older%20children%20across%20all%20three%20domains%20of%20early%20child%20development.%20Conclusions%20Several%20factors%20were%20identified%20to%20be%20associated%20with%20early%20child%20development.%20As%20children%20grow%20older%2C%20obstetric%20parameters%2C%20for%20example%2C%20gestational%20age%2C%20might%20become%20less%20relevant%20compared%20with%20sociodemographic%20factors%2C%20for%20example%2C%20parental%20education.%22%2C%22date%22%3A%222023-09-22%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1111%5C%2Fcch.13177%22%2C%22ISSN%22%3A%221365-2214%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fonlinelibrary.wiley.com%5C%2Fdoi%5C%2Fabs%5C%2F10.1111%5C%2Fcch.13177%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222024-08-27T10%3A18%3A09Z%22%7D%7D%2C%7B%22key%22%3A%22SNBL72U5%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Nerius%20et%20al.%22%2C%22parsedDate%22%3A%222023-09-14%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3ENerius%2C%20Lena%2C%20Mandy%20Vogel%2C%20Uta%20Ceglarek%2C%20Wieland%20Kiess%2C%20Ronald%20Biemann%2C%20Holger%20Stepan%2C%20and%20J%26%23xFC%3Brgen%20Kratzsch.%20%26%23x201C%3BBone%20Turnover%20in%20Lactating%20and%20Nonlactating%20Women.%26%23x201D%3B%20%3Ci%3EArchives%20of%20Gynecology%20and%20Obstetrics%3C%5C%2Fi%3E%2C%20September%2014%2C%202023.%20%3Ca%20class%3D%27zp-ItemURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs00404-023-07189-0%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs00404-023-07189-0%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Bone%20turnover%20in%20lactating%20and%20nonlactating%20women%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Lena%22%2C%22lastName%22%3A%22Nerius%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Uta%22%2C%22lastName%22%3A%22Ceglarek%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ronald%22%2C%22lastName%22%3A%22Biemann%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Holger%22%2C%22lastName%22%3A%22Stepan%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J%5Cu00fcrgen%22%2C%22lastName%22%3A%22Kratzsch%22%7D%5D%2C%22abstractNote%22%3A%22During%20lactation%2C%20bone%20turnover%20increases%2C%20reflecting%20the%20mobilization%20of%20Calcium%20from%20maternal%20skeletal%20stores%20and%20resulting%20in%20bone%20loss.%20However%2C%20mechanisms%20are%20not%20yet%20fully%20understood%2C%20and%20previous%20studies%20have%20been%20comparatively%20small.%20We%20aim%20to%20assess%20bone%20metabolism%20during%20lactation%20by%20comparing%20bone-metabolism-related-parameters%20between%20large%20cohorts%20of%20lactating%20and%20nonlactating%20women.%22%2C%22date%22%3A%222023-09-14%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1007%5C%2Fs00404-023-07189-0%22%2C%22ISSN%22%3A%221432-0711%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs00404-023-07189-0%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222024-06-21T06%3A54%3A17Z%22%7D%7D%2C%7B%22key%22%3A%22PJIEJAUS%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Strauch%20et%20al.%22%2C%22parsedDate%22%3A%222023-09-01%22%2C%22numChildren%22%3A2%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EStrauch%2C%20Jacqueline-Mich%26%23xE9%3Ble%2C%20Mandy%20Vogel%2C%20Christof%20Meigen%2C%20Uta%20Ceglarek%2C%20J%26%23xFC%3Brgen%20Kratzsch%2C%20Anja%20Willenberg%2C%20and%20Wieland%20Kiess.%20%26%23x201C%3BPediatric%20Reference%20Values%20of%20Alkaline%20Phosphatase%3A%20Analysis%20from%20a%20German%20Population-Based%20Cohort%20and%20Influence%20of%20Anthropometric%20and%20Blood%20Parameters.%26%23x201D%3B%20%3Ci%3EBone%3C%5C%2Fi%3E%20174%20%28September%201%2C%202023%29%3A%20116809.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.bone.2023.116809%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.bone.2023.116809%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Pediatric%20reference%20values%20of%20alkaline%20phosphatase%3A%20Analysis%20from%20a%20German%20population-based%20cohort%20and%20influence%20of%20anthropometric%20and%20blood%20parameters%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jacqueline-Mich%5Cu00e9le%22%2C%22lastName%22%3A%22Strauch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christof%22%2C%22lastName%22%3A%22Meigen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Uta%22%2C%22lastName%22%3A%22Ceglarek%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J%5Cu00fcrgen%22%2C%22lastName%22%3A%22Kratzsch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anja%22%2C%22lastName%22%3A%22Willenberg%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%5D%2C%22abstractNote%22%3A%22Background%5CnDue%20to%20different%20growth%20and%20metabolic%20processes%2C%20reference%20values%20of%20alkaline%20phosphatase%20%28AP%29%20for%20children%20aged%203%5Cu00a0month%20to%2018%5Cu00a0years%20are%20dependent%20on%20age%20and%20sex.%20They%20are%20not%20constant%20and%20differ%20from%20those%20of%20adults%20due%20to%20the%20growth%20processes%20taking%20place.%20Accordingly%2C%20reference%20levels%20of%20AP%20continuous%20across%20these%20ages%20were%20generated%20for%20boys%20and%20girls%20based%20on%20of%20a%20large%20German%20health-%20and%20population-based%20study%2C%20LIFE%20Child.%20We%20considered%20AP%20at%20different%20growth%20and%20Tanner%20stages%20and%20additionally%20its%20association%20with%20other%20anthropometric%20parameters.%20The%20association%20between%20AP%20and%20BMI%20was%20of%20particulary%20great%20interest%20due%20to%20controversial%20literature%20on%20this%20topic.%20The%20role%20of%20AP%20in%20liver%20metabolism%20was%20investigated%20by%20examining%20ALAT%2C%20ASAT%2C%20and%20GGT.%5CnMethods%5Cn3976%20healthy%20children%20%2812%2C093%20visits%29%20were%20included%20from%20the%20LIFE%20Child%20study%20from%202011%20to%202020.%20The%20subjects%5Cu00b4%20age%20ranged%20from%203%5Cu00a0months%20to%2018%5Cu00a0years.%20Serum%20samples%20from%203704%20subjects%20%2810%2C272%20cases%2C%201952%20boys%20and%201753%20girls%29%20were%20analysed%20for%20AP%20after%20applying%20specific%20exclusion%20criteria.%20After%20calculating%20of%20reference%20percentiles%2C%20associations%20between%20AP%20and%20height-SDS%2C%20growth%20velocity%2C%20BMI-SDS%2C%20Tanner%20stage%20and%20the%20liver%20enzymes%20ALAT%2C%20ASAT%20and%20GGT%20were%20examined%20via%20linear%20regression%20models.%5CnResults%5CnIn%20the%20continuous%20reference%20levels%2C%20AP%20showed%20a%20first%20peak%20during%20the%20first%20year%20of%20life%2C%20followed%20by%20a%20plateau%20at%20a%20lower%20level%20until%20the%20start%20of%20puberty.%20In%20girls%2C%20AP%20increased%20beginning%20at%20the%20age%208%2C%20with%20a%20peak%20around%2011%5Cu00a0years%2C%20in%20boys%20beginning%20at%20the%20age%209%2C%20with%20a%20peak%20around%20age%2013.%20Afterwards%2C%20AP%20values%20decreased%20continuously%20until%20age%2018.%20In%20Tanner%20stages%201%20and%202%2C%20AP%20levels%20did%20not%20differ%20between%20the%20two%20sexes.%20We%20found%20a%20strong%20positive%20association%20between%20AP-SDS%20and%20BMI-SDS.%20We%20also%20observed%20a%20significantly%20positive%20association%20between%20AP-SDS%20and%20height-SDS%2C%20which%20was%20stronger%20in%20boys%20than%20in%20girls.%20We%20found%20different%20intensities%20in%20the%20associations%20of%20AP%20with%20growth%20velocity%20depending%20on%20age%20group%20and%20sex.%20Furthermore%2C%20we%20found%20a%20significantly%20positive%20association%20between%20ALAT%20and%20AP%20in%20girls%20but%20not%20in%20boys%2C%20whereas%20ASAT-SDS%20and%20GGT-SDS%20were%20significantly%20positively%20associated%20with%20AP-SDS%20in%20both%20sexes.%5CnConclusion%5CnSex%20and%20age%2C%20but%20also%20BMI%20may%20act%20as%20confounding%20factors%20for%20AP%20reference%20ranges.%20Our%20data%20confirm%20the%20remarkable%20association%20between%20AP%20and%20growth%20velocity%20%28or%20height-SDS%2C%20respectively%29%20during%20infancy%20and%20puberty.%20In%20addition%2C%20we%20were%20able%20to%20specify%20the%20associations%20between%20AP%20and%20ALAT%2C%20ASAT%2C%20and%20GGT%20and%20their%20differences%20in%20both%20sexes.%20These%20relations%20should%20be%20considered%20when%20evaluating%20liver%20and%20bone%20metabolism%20markers%2C%20especially%20in%20infancy.%22%2C%22date%22%3A%222023-09-01%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1016%5C%2Fj.bone.2023.116809%22%2C%22ISSN%22%3A%228756-3282%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.sciencedirect.com%5C%2Fscience%5C%2Farticle%5C%2Fpii%5C%2FS8756328223001424%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222024-06-21T06%3A52%3A58Z%22%7D%7D%2C%7B%22key%22%3A%229QSQSGQJ%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Kabbani%20et%20al.%22%2C%22parsedDate%22%3A%222023-08-08%22%2C%22numChildren%22%3A3%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EKabbani%2C%20Noura%2C%20Holger%20Stepan%2C%20Matthias%20Bl%26%23xFC%3Bher%2C%20Thomas%20Ebert%2C%20Ronny%20Baber%2C%20Mandy%20Vogel%2C%20Wieland%20Kiess%2C%20et%20al.%20%26%23x201C%3BAssociation%20between%20TGF%26%23x3B2%3B1%20Levels%20in%20Cord%20Blood%20and%20Weight%20Progress%20in%20the%20First%20Year%20of%20Life.%26%23x201D%3B%20%3Ci%3EBiomedicines%3C%5C%2Fi%3E%2011%2C%20no.%208%20%28August%208%2C%202023%29%3A%202220.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Fbiomedicines11082220%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Fbiomedicines11082220%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Association%20between%20TGF%5Cu03b21%20Levels%20in%20Cord%20Blood%20and%20Weight%20Progress%20in%20the%20First%20Year%20of%20Life%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Noura%22%2C%22lastName%22%3A%22Kabbani%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Holger%22%2C%22lastName%22%3A%22Stepan%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Matthias%22%2C%22lastName%22%3A%22Bl%5Cu00fcher%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Thomas%22%2C%22lastName%22%3A%22Ebert%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ronny%22%2C%22lastName%22%3A%22Baber%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Michael%22%2C%22lastName%22%3A%22Stumvoll%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jana%22%2C%22lastName%22%3A%22Breitfeld%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ulrike%22%2C%22lastName%22%3A%22L%5Cu00f6ssner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anke%22%2C%22lastName%22%3A%22T%5Cu00f6njes%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Susanne%22%2C%22lastName%22%3A%22Schrey-Petersen%22%7D%5D%2C%22abstractNote%22%3A%22Transforming%20growth%20factor%20beta-1%20%28TGF%5Cu03b21%29%20is%20an%20adipokine%20secreted%20from%20adipose%20tissue%2C%20placental%20tissue%20and%20immune%20cells%20with%20a%20role%20in%20cell%20proliferation%2C%20cell%20apoptosis%20and%20angiogenic%20proliferation.%20The%20role%20of%20TGF%5Cu03b21%20in%20pregnancy%20and%20child%20growth%20and%20the%20source%20of%20cord%20TGF%5Cu03b21%20are%20yet%20unknown.%20In%20this%20study%2C%20we%20sought%20to%20clarify%20the%20correlation%20of%20TGF%5Cu03b21%20levels%20with%20parameters%20of%20intrauterine%20growth%20and%20child%20growth%20during%20the%20first%20year%20of%20life%2C%20and%20to%20determine%20whether%20their%20source%20is%20primarily%20of%20fetal%20or%20maternal%20origin.%20Serum%20samples%20and%20anthropometric%20measurements%20were%20obtained%20from%20the%20LIFE%20Child%20cohort%20of%2079%20healthy%20mother-child%20pairs.%20Measurements%20were%20conducted%20using%20enzyme-linked%20immunosorbent%20assays.%20Statistical%20analyses%20including%20Mann-Whitney%20U-test%2C%20correlation%20analyses%20and%20linear%20regression%20analyses%20were%20performed%20using%20GraphPad%20Prism%20and%20R.%20TGF%5Cu03b21%20levels%20were%20significantly%20higher%20in%20cord%20than%20in%20maternal%20serum%2C%20suggesting%20a%20fetal%20origin.%20Multivariate%20regression%20analyses%20revealed%20strong%20positive%20associations%20between%20cord%20TGF%5Cu03b21%20levels%20at%20birth%20and%20child%20weight%20at%20U6.%20Furthermore%2C%20cord%20TGF%5Cu03b21%20was%20significantly%20correlated%20with%20child%20weight%20at%20approximately%20one%20year%20of%20age.%20An%20increase%20of%2010%2C000%20pg%5C%2FmL%20in%20cord%20TGF%5Cu03b21%20concentrations%20at%20birth%20was%20associated%20with%20a%20higher%20body%20weight%20of%20201%20g%20at%20roughly%20one%20year%20of%20age%20when%20adjusted%20for%20sex.%22%2C%22date%22%3A%222023-08-08%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.3390%5C%2Fbiomedicines11082220%22%2C%22ISSN%22%3A%222227-9059%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222024-08-27T13%3A09%3A35Z%22%7D%7D%2C%7B%22key%22%3A%223PM9343R%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Maidowski%20et%20al.%22%2C%22parsedDate%22%3A%222023-08-02%22%2C%22numChildren%22%3A2%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EMaidowski%2C%20Ludwig%2C%20Wieland%20Kiess%2C%20Ronny%20Baber%2C%20Anne%20Dathan-Stumpf%2C%20Uta%20Ceglarek%2C%20and%20Mandy%20Vogel.%20%26%23x201C%3BTracking%20of%20Serum%20Lipids%20in%20Healthy%20Children%20on%20a%20Year-to-Year%20Basis.%26%23x201D%3B%20%3Ci%3EBMC%20Cardiovascular%20Disorders%3C%5C%2Fi%3E%2023%2C%20no.%201%20%28August%202%2C%202023%29%3A%20386.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs12872-023-03391-9%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs12872-023-03391-9%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Tracking%20of%20serum%20lipids%20in%20healthy%20children%20on%20a%20year-to-year%20basis%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ludwig%22%2C%22lastName%22%3A%22Maidowski%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ronny%22%2C%22lastName%22%3A%22Baber%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anne%22%2C%22lastName%22%3A%22Dathan-Stumpf%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Uta%22%2C%22lastName%22%3A%22Ceglarek%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%5D%2C%22abstractNote%22%3A%22OBJECTIVES%3A%20To%20assess%20the%20stability%20of%20lipid%20profiles%20throughout%20childhood%20and%20evaluate%20their%20onset%20and%20dynamic.%5CnMATERIALS%20AND%20METHODS%3A%20Lipid%20markers%20were%20longitudinally%20measured%20in%20more%20than%201300%20healthy%20children%20from%20the%20LIFE%20Child%20study%20%28Germany%29%20and%20categorized%20into%20normal%2C%20at-risk%2C%20or%20adverse.%20Year-to-year%20intra-person%20persistence%20of%20the%20categories%20during%20follow-ups%20was%20examined%20and%20Pearson%27s%20correlation%20coefficient%20was%20calculated.%5CnRESULTS%3A%20We%20found%20strong%20positive%20correlations%20for%20TC%2C%20LDL-C%20and%20ApoB%20%28r%5Cu2009%3E%5Cu20090.75%2C%20p%5Cu2009%3C%5Cu20090.001%29%20from%20the%20age%20of%20four%20years.%20Correlations%20were%20lowest%20during%20the%20first%20two%20years%20of%20life.%20Most%20children%20with%20normal%20levels%20also%20had%20normal%20levels%20the%20following%20year.%20Children%20with%20at-risk%20levels%20showed%20a%20tendency%20towards%20normal%20levels%20at%20the%20follow-up%20visit.%20Adverse%20levels%20of%20TC%2C%20LDL-C%2C%20ApoB%20%28all%20ages%29%2C%20and%20HDL-C%20%28from%20age%2015%29%20persisted%20in%20more%20than%20half%20of%20the%20affected%20children.%20Age-dependent%20patterns%20of%20stability%20were%20most%20pronounced%20and%20similar%20for%20TC%2C%20LDL-C%2C%20and%20ApoB.%5CnCONCLUSIONS%3A%20Normal%20levels%20of%20serum%20lipids%20show%20high%20stability%20and%20adverse%20levels%20stabilized%20in%20early%20childhood%20for%20TC%2C%20LDL%2C%20and%20ApoB.%20At-risk%20and%20adverse%20levels%20of%20TC%2C%20LDL-C%20or%20ApoB%20may%20warrant%20further%20or%20repeated%20diagnostic%20measurements%20with%20regards%20to%20preventing%20CVD%20in%20the%20long%20run.%22%2C%22date%22%3A%222023-08-02%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1186%5C%2Fs12872-023-03391-9%22%2C%22ISSN%22%3A%221471-2261%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222024-08-27T13%3A09%3A58Z%22%7D%7D%2C%7B%22key%22%3A%22RWLYJMIU%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22St%5Cu00fcrzebecher%20et%20al.%22%2C%22parsedDate%22%3A%222023-08-01%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3ESt%26%23xFC%3Brzebecher%2C%20P.%2C%20M.%20Schlingmann%2C%20K.%20Uttinger%2C%20M.%20Vogel%2C%20U.%20Ceglarek%2C%20B.%20Isermann%2C%20W.%20Kiess%2C%20A.%20K%26%23xF6%3Brner%2C%20and%20U.%20Laufs.%20%26%23x201C%3BLipoprotein%28A%29%20Serum%20Concentrations%20in%20Children%20Are%20Independent%20of%20Age%2C%20Sex%2C%20or%20Body%20Mass%20Index.%26%23x201D%3B%20In%20%3Ci%3EAtherosclerosis%3C%5C%2Fi%3E%2C%20379%3AS20.%20Elsevier%2C%202023.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.atherosclerosis.2023.06.739%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.atherosclerosis.2023.06.739%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22conferencePaper%22%2C%22title%22%3A%22Lipoprotein%28A%29%20serum%20concentrations%20in%20children%20are%20independent%20of%20age%2C%20sex%2C%20or%20body%20mass%20index%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22P.%22%2C%22lastName%22%3A%22St%5Cu00fcrzebecher%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22M.%22%2C%22lastName%22%3A%22Schlingmann%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22K.%22%2C%22lastName%22%3A%22Uttinger%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22M.%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22U.%22%2C%22lastName%22%3A%22Ceglarek%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22B.%22%2C%22lastName%22%3A%22Isermann%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22W.%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22A.%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22U.%22%2C%22lastName%22%3A%22Laufs%22%7D%5D%2C%22abstractNote%22%3A%22%22%2C%22date%22%3A%222023-08-01%22%2C%22proceedingsTitle%22%3A%22Atherosclerosis%22%2C%22conferenceName%22%3A%22%22%2C%22language%22%3A%22English%22%2C%22DOI%22%3A%2210.1016%5C%2Fj.atherosclerosis.2023.06.739%22%2C%22ISBN%22%3A%22%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.atherosclerosis-journal.com%5C%2Farticle%5C%2FS0021-9150%2823%2904831-1%5C%2Ffulltext%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222024-08-27T13%3A10%3A07Z%22%7D%7D%2C%7B%22key%22%3A%223DCAUG36%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Sobek%20et%20al.%22%2C%22parsedDate%22%3A%222023-08%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3ESobek%2C%20Carolin%2C%20Peggy%20Ober%2C%20and%20Mandy%20Vogel.%20%26%23x201C%3BSchulen%20im%20%28Klima-%29Wandel%20%26%23×2013%3B%20Handlungsfelder.%26%23x201D%3B%20%3Ci%3EKinder-%20und%20Jugendmedizin%3C%5C%2Fi%3E%2023%2C%20no.%204%20%28August%202023%29%3A%20229%26%23×2013%3B34.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1055%5C%2Fa-2104-3463%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1055%5C%2Fa-2104-3463%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Schulen%20im%20%28Klima-%29Wandel%20%5Cu2013%20Handlungsfelder%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Carolin%22%2C%22lastName%22%3A%22Sobek%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Peggy%22%2C%22lastName%22%3A%22Ober%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%5D%2C%22abstractNote%22%3A%22Die%20Grundlagen%20bewusster%20umweltbezogener%20Einstellungen%20und%20Verhaltensweisen%20werden%20fr%5Cu00fch%20gelegt.%20Kinderg%5Cu00e4rten%20und%20Schulen%20als%20Orte%20des%20gemeinsamen%20Lebens%20und%20Lernens%20k%5Cu00f6nnen%20%5Cu2013%20neben%20dem%20Wissen%20%5Cu2013%20nachhaltige%20Normen%20und%20Werte%20vermitteln%20und%20festigen.%20Diese%20erm%5Cu00f6glichen%20es%20den%20Kindern%2C%20Ma%5Cu00dfnahmen%20gegen%20den%20Klimawandel%20zu%20verstehen%20und%20als%20selbstverst%5Cu00e4ndlich%20in%20ihrem%20Leben%20zu%20akzeptieren.%20Schulverpflegung%2C%20Schulweg%20und%20Schulg%5Cu00e4rten%20sind%20einige%20m%5Cu00f6gliche%20Handlungsfelder.%20Sie%20k%5Cu00f6nnen%20genutzt%20werden%2C%20Kinder%20f%5Cu00fcr%20umweltrelevante%20Themen%20zu%20sensibilisieren%20und%20so%20auch%20zuk%5Cu00fcnftigen%20Generationen%20eine%20lebenswerte%20Umwelt%20zu%20sichern.%22%2C%22date%22%3A%222023%5C%2F08%22%2C%22language%22%3A%22de%22%2C%22DOI%22%3A%2210.1055%5C%2Fa-2104-3463%22%2C%22ISSN%22%3A%221617-0288%2C%202567-577X%22%2C%22url%22%3A%22http%3A%5C%2F%5C%2Fwww.thieme-connect.de%5C%2FDOI%5C%2FDOI%3F10.1055%5C%2Fa-2104-3463%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222024-08-13T13%3A01%3A29Z%22%7D%7D%2C%7B%22key%22%3A%22VJJBWLYM%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Vogel%20et%20al.%22%2C%22parsedDate%22%3A%222023-07-17%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EVogel%2C%20Mandy%2C%20Ruth%20Gausche%2C%20Tanja%20Poulain%2C%20and%20Wieland%20Kiess.%20%26%23x201C%3BWie%20Die%20Ungleiche%20Verteilung%20von%20Risiken%20Und%20Chancen%20Im%20Kindesalter%20Die%20Gesundheit%20Pr%26%23xE4%3Bgt%20%26%23×2013%3B%20Ein%20Leben%20Lang%20%28Und%20Dar%26%23xFC%3Bber%20Hinaus%29%2C%26%23x201D%3B%2061%26%23×2013%3B72%2C%202023.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22bookSection%22%2C%22title%22%3A%22Wie%20die%20ungleiche%20Verteilung%20von%20Risiken%20und%20Chancen%20im%20Kindesalter%20die%20Gesundheit%20pr%5Cu00e4gt%20%5Cu2013%20ein%20Leben%20lang%20%28und%20dar%5Cu00fcber%20hinaus%29%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ruth%22%2C%22lastName%22%3A%22Gausche%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%5D%2C%22abstractNote%22%3A%22%22%2C%22bookTitle%22%3A%22%22%2C%22date%22%3A%222023-07-17%22%2C%22language%22%3A%22%22%2C%22ISBN%22%3A%22978-3-96023-517-0%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222024-09-02T15%3A07%3A07Z%22%7D%7D%2C%7B%22key%22%3A%22S2ZWAVJH%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Hammel%20et%20al.%22%2C%22parsedDate%22%3A%222023-07%22%2C%22numChildren%22%3A2%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EHammel%2C%20Maximiliane%20Chiara%2C%20Robert%20Stein%2C%20J%26%23xFC%3Brgen%20Kratzsch%2C%20Mandy%20Vogel%2C%20Alexander%20J.%20Eckert%2C%20Rima%20Destya%20Triatin%2C%20Marco%20Colombo%2C%20et%20al.%20%26%23x201C%3BFasting%20Indices%20of%20Glucose-Insulin-Metabolism%20across%20Life%20Span%20and%20Prediction%20of%20Glycemic%20Deterioration%20in%20Children%20with%20Obesity%20from%20New%20Diagnostic%20Cut-Offs.%26%23x201D%3B%20%3Ci%3EThe%20Lancet%20Regional%20Health.%20Europe%3C%5C%2Fi%3E%2030%20%28July%202023%29%3A%20100652.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.lanepe.2023.100652%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.lanepe.2023.100652%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Fasting%20indices%20of%20glucose-insulin-metabolism%20across%20life%20span%20and%20prediction%20of%20glycemic%20deterioration%20in%20children%20with%20obesity%20from%20new%20diagnostic%20cut-offs%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Maximiliane%20Chiara%22%2C%22lastName%22%3A%22Hammel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Robert%22%2C%22lastName%22%3A%22Stein%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J%5Cu00fcrgen%22%2C%22lastName%22%3A%22Kratzsch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Alexander%20J.%22%2C%22lastName%22%3A%22Eckert%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Rima%20Destya%22%2C%22lastName%22%3A%22Triatin%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Marco%22%2C%22lastName%22%3A%22Colombo%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christof%22%2C%22lastName%22%3A%22Meigen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ronny%22%2C%22lastName%22%3A%22Baber%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Juraj%22%2C%22lastName%22%3A%22Stanik%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ulrike%22%2C%22lastName%22%3A%22Spielau%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anette%22%2C%22lastName%22%3A%22Stoltze%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Kerstin%22%2C%22lastName%22%3A%22Wirkner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anke%22%2C%22lastName%22%3A%22T%5Cu00f6njes%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Harold%22%2C%22lastName%22%3A%22Snieder%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Reinhard%20W.%22%2C%22lastName%22%3A%22Holl%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Michael%22%2C%22lastName%22%3A%22Stumvoll%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Matthias%22%2C%22lastName%22%3A%22Bl%5Cu00fcher%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%5D%2C%22abstractNote%22%3A%22BACKGROUND%3A%20Fasting%20indices%20of%20glucose-insulin-metabolism%20are%20an%20easy%20and%20affordable%20tool%20to%20assess%20insulin%20resistance.%20We%20aimed%20to%20establish%20reference%20ranges%20for%20fasting%20insulin%20indices%20that%20reflect%20age-dependent%20variation%20over%20the%20entire%20life%20span%20and%20subsequently%20test%20their%20clinical%20application%20regarding%20the%20prediction%20of%20glycemic%20deterioration%20in%20children.%5CnMETHODS%3A%20We%20calculated%20age-%20and%20puberty-dependent%20reference%20values%20for%20HOMA-IR%2C%20HOMA2-IR%2C%20HOMA-%5Cu03b2%2C%20McAuley%20index%2C%20fasting%20insulin%2C%20and%20fasting%20glucose%20from%206994%20observations%20of%205512%20non-obese%20healthy%20subjects%20aged%205-80%20years.%20Applying%20those%20references%2C%20we%20determined%20the%20prevalence%20of%20insulin%20resistance%20among%202538%20subjects%20with%20obesity.%20Furthermore%2C%20we%20investigated%20the%20intraindividual%20stability%20and%20the%20predictive%20values%20for%20future%20dysglycemia%20of%20these%20fasting%20indices%20in%20516%20children%20and%20adolescents%20with%20obesity%20up%20to%2019%20years%20of%20follow-up.%20We%20validated%20the%20results%20in%20three%20independent%20cohorts.%5CnFINDINGS%3A%20There%20was%20a%20strong%20age-dependent%20variation%20of%20all%20indices%20throughout%20the%20life%20span%2C%20including%20prolonged%20recovery%20of%20pubertal%20insulin%20resistance%20and%20a%20subsequent%20continuous%20increase%20throughout%20adulthood.%20Already%20from%20age%205%20years%20onwards%2C%20%3E40%25%20of%20children%20with%20obesity%20presented%20with%20elevated%20parameters%20of%20insulin%20resistance.%20Applying%20newly%20developed%20reference%20ranges%2C%20insulin%20resistance%20among%20children%20with%20obesity%20doubled%20the%20risk%20for%20future%20glycemic%20deterioration%20%28HOMA-IR%20HR%201.88%20%2895%25%20CI%201.1-3.21%29%29%2C%20fasting%20insulin%20HR%201.89%20%2895%25%20CI%201.11-3.23%29.%20In%20contrast%2C%20fasting%20glucose%20alone%20was%20not%20predictive%20for%20emerging%20dysglycemia%20in%20children%20with%20obesity%20%28HR%201.03%20%2895%25%20CI%200.62-1.71%29%29.%20The%20new%20insulin-based%20thresholds%20were%20superior%20to%20fasting%20glucose%20and%20HbA1c%20in%20detecting%20children%20eventually%20manifesting%20with%20dysglycemia%20in%20prospective%20analyses.%5CnINTERPRETATION%3A%20The%20variation%20of%20fasting%20glucose-insulin-metabolism%20across%20the%20life%20span%20necessitates%20age-specific%20reference%20ranges.%20The%20improved%20prediction%20of%20future%20glycemic%20deterioration%20by%20indices%20based%20on%20fasting%20insulin%20beyond%20simple%20glucose%20measures%20alone%20could%20help%20to%20stratify%20risk%20characteristics%20of%20children%20with%20obesity%20in%20order%20to%20guide%20patient-tailored%20prevention%20and%20intervention%20approaches.%5CnFUNDING%3A%20German%20Research%20Foundation%20%28DFG%29-through%20SFB%201052%2C%20project%20number%20209933838%2C%20subproject%20C5%3B%20Federal%20Ministry%20of%20Education%20and%20Research%2C%20Germany%3B%20European%20Union-European%20Regional%20Development%20Fund%3B%20Free%20State%20of%20Saxony.%20The%20German%20Diabetes%20Association%2C%20the%20CarbHealth%20consortium%20%2801EA1908B%29.%20EU-IMI2-Consortium%20SOPHIA%20%28grant%20agreement%20No%20875534%29%2C%20German%20Center%20for%20Diabetes%20Research%20%28DZD%29%2C%20grant%20number%2082DZD14E03.%22%2C%22date%22%3A%222023-07%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1016%5C%2Fj.lanepe.2023.100652%22%2C%22ISSN%22%3A%222666-7762%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222024-06-17T12%3A11%3A40Z%22%7D%7D%2C%7B%22key%22%3A%22W2VX5D8K%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Rauscher%20et%20al.%22%2C%22parsedDate%22%3A%222023-07%22%2C%22numChildren%22%3A2%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3ERauscher%2C%20Franziska%20G.%2C%20Andreas%20Hiemisch%2C%20Wieland%20Kiess%2C%20and%20Ralf%20Blendowske.%20%26%23x201C%3BMonochromatic%20Ocular%20High-Order%20Aberrations%20in%20Children%20and%20Adolescents.%26%23x201D%3B%20%3Ci%3EOphthalmic%20%26amp%3B%20Physiological%20Optics%3A%20The%20Journal%20of%20the%20British%20College%20of%20Ophthalmic%20Opticians%20%28Optometrists%29%3C%5C%2Fi%3E%2043%2C%20no.%204%20%28July%202023%29%3A%20842%26%23×2013%3B59.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fopo.13151%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fopo.13151%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Monochromatic%20ocular%20high-order%20aberrations%20in%20children%20and%20adolescents%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Franziska%20G.%22%2C%22lastName%22%3A%22Rauscher%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andreas%22%2C%22lastName%22%3A%22Hiemisch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ralf%22%2C%22lastName%22%3A%22Blendowske%22%7D%5D%2C%22abstractNote%22%3A%22PURPOSE%3A%20To%20investigate%20the%20prevalence%20and%20repeatability%20of%20high-order%20aberrations%20%28HOAs%29%20from%20non-cyclopleged%20eyes%20in%201515%20children%20and%20adolescents%202.5-18%5Cu2009years%20of%20age.%5CnMETHODS%3A%20The%20Leipzig%20Research%20Centre%20for%20Civilization%20Diseases%20%28LIFE%29-Child%20study%20is%20a%20population-based%2C%20prospective%2C%20observational%20single-centre%20study%20that%20investigates%20the%20development%20of%20children%20and%20adolescents%20in%20Germany.%20Wavefront%20measurements%20were%20repeated%20three%20times%20in%20each%20eye%20of%201515%20healthy%20subjects.%20Results%20were%20described%20by%2036%20Zernike%20coefficients%20for%20a%205%5Cu2009mm%20reference%20pupil%20diameter.%20Short-term%20repeatability%20is%20given%20for%20each%20coefficient.%20The%20impact%20on%20vision%20is%20described%20by%20the%20root%20mean%20squared%20%28RMS%29%20value%20of%20the%20HOA%20Zernike%20coefficients.%5CnRESULTS%3A%20High-order%20aberrations%20were%20dominated%20by%20five%20contributions.%20For%201004%20right%20eyes%3A%20spherical%20aberration%20%28c12%20%5Cu2009%3D%5Cu20090.06%5Cu2009%5Cu00b1%5Cu20090.07%5Cu2009%5Cu03bcm%29%2C%20coma%20%28c7%20%5Cu2009%3D%5Cu20090.03%5Cu2009%5Cu00b1%5Cu20090.09%5Cu2009%5Cu03bcm%2C%20c8%20%5Cu2009%3D%5Cu20090.03%5Cu2009%5Cu00b1%5Cu20090.06%5Cu2009%5Cu03bcm%29%20and%20trefoil%20%28c6%20%5Cu2009%3D%5Cu2009-0.01%5Cu2009%5Cu00b1%5Cu20090.07%5Cu2009%5Cu03bcm%2C%20c9%20%5Cu2009%3D%5Cu20090.008%5Cu2009%5Cu00b1%5Cu20090.06%5Cu2009%5Cu03bcm%29.%20The%20RMS%20value%20was%200.18%5Cu2009%5Cu00b1%5Cu20090.06%5Cu2009%5Cu03bcm.%20Modes%20higher%20than%20fourth%20order%20do%20not%20contribute%20clinically%20to%20the%20aberrations.%20HOAs%20show%20no%20clinically%20significant%20dependency%20with%20age.%20Instead%2C%20HOA%20values%20agree%20well%20with%20previous%20results%20on%20aberrations%20in%20adult%20eyes.%20Spherical%20aberration%20was%20highly%20correlated%20between%20the%20two%20eyes.%20Repeatability%20was%20worst%20for%20coma%2C%200.033%5Cu2009%5Cu03bcm%2C%20due%20to%20variability%20in%20the%20alignment%20of%20the%20pupil%20centre.%20The%20left%20eye%20showed%2C%20on%20average%2C%20a%200.08%5Cu2009mm%20larger%20pupil%20diameter%20than%20the%20right%20eye%20%28p%5Cu2009%3C%5Cu20090.02%29.%5CnCONCLUSIONS%3A%20Across%20the%20age%20span%20from%202.5%20to%2018%5Cu2009years%2C%20we%20see%20the%20same%20distribution%20of%20HOA%20as%20for%20adults.%20We%20established%20that%20only%20five%20Zernike%20coefficients%2C%20spherical%20aberration%2C%20coma%20and%20trefoil%20were%20of%20clinical%20significance%20in%20healthy%20eyes.%20A%20high%20correlation%20between%20the%20two%20eyes%20for%20spherical%20aberration%20suggests%20a%20common%20blueprint%20for%20each%20eye%20in%20any%20one%20subject.%22%2C%22date%22%3A%222023-07%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1111%5C%2Fopo.13151%22%2C%22ISSN%22%3A%221475-1313%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222024-08-27T11%3A44%3A47Z%22%7D%7D%2C%7B%22key%22%3A%22FCXCZBGL%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Wex%20et%20al.%22%2C%22parsedDate%22%3A%222023-03-23%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EWex%2C%20Isabel%2C%20Mandy%20Geserick%2C%20Tim%20Leibert%2C%20Ulrike%20Igel%2C%20Carolin%20Sobek%2C%20Christof%20Meigen%2C%20Wieland%20Kiess%2C%20and%20Mandy%20Vogel.%20%26%23x201C%3BActive%20School%20Transport%20in%20an%20Urban%20Environment%3APrevalence%20and%20Perceived%20Barriers.%26%23x201D%3B%20%3Ci%3EBMC%20Public%20Health%3C%5C%2Fi%3E%2023%2C%20no.%201%20%28March%2023%2C%202023%29.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs12889-023-15464-7%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs12889-023-15464-7%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Active%20school%20transport%20in%20an%20urban%20environment%3Aprevalence%20and%20perceived%20barriers%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Isabel%22%2C%22lastName%22%3A%22Wex%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Geserick%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tim%22%2C%22lastName%22%3A%22Leibert%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ulrike%22%2C%22lastName%22%3A%22Igel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Carolin%22%2C%22lastName%22%3A%22Sobek%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christof%22%2C%22lastName%22%3A%22Meigen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%5D%2C%22abstractNote%22%3A%22LIFE%20Child%20has%20been%20retrospectively%20registered%20with%20ClinicalTrials.gov%20%28NCT02550236%29.%22%2C%22date%22%3A%2203%5C%2F23%5C%2F2023%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1186%5C%2Fs12889-023-15464-7%22%2C%22ISSN%22%3A%221471-2458%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fpubmed.ncbi.nlm.nih.gov%5C%2F36959624%5C%2F%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-06T21%3A19%3A38Z%22%7D%7D%2C%7B%22key%22%3A%22KXRLYRQ4%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22S%5Cu00f6hnel%20et%20al.%22%2C%22parsedDate%22%3A%222023-03-17%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3ES%26%23xF6%3Bhnel%2C%20Tanja%2C%20Christof%20Meigen%2C%20Andreas%20Hiemisch%2C%20Siegfried%20Wahl%2C%20Focke%20Ziemssen%2C%20Carolin%20Truckenbrod%2C%20Katharina%20H%26%23xFC%3Bbner%2C%20and%20Wieland%20Kiess.%20%26%23x201C%3BNormative%20Data%20for%20Macular%20and%20Retinal%20Nerve%20Fibre%20Layer%20Thickness%20in%20Healthy%20German%20Children%20and%20Adolescents%20Using%20Optical%20Coherence%20Tomography.%26%23x201D%3B%20%3Ci%3EOphthalmic%20and%20Physiological%20Optics%3C%5C%2Fi%3E%2C%20March%2017%2C%202023%2C%20opo.13123.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fopo.13123%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fopo.13123%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Normative%20data%20for%20macular%20and%20retinal%20nerve%20fibre%20layer%20thickness%20in%20healthy%20German%20children%20and%20adolescents%20using%20optical%20coherence%20tomography%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22S%5Cu00f6hnel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christof%22%2C%22lastName%22%3A%22Meigen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andreas%22%2C%22lastName%22%3A%22Hiemisch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Siegfried%22%2C%22lastName%22%3A%22Wahl%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Focke%22%2C%22lastName%22%3A%22Ziemssen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Carolin%22%2C%22lastName%22%3A%22Truckenbrod%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Katharina%22%2C%22lastName%22%3A%22H%5Cu00fcbner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%5D%2C%22abstractNote%22%3A%22Purpose%3A%20To%20establish%20normative%20data%20for%20macular%20thickness%2C%20macular%20volume%20and%20peripapillary%20retinal%20nerve%20fibre%20layer%20%28RNFL%29%20thickness%20using%20Spectralis%5Cu00ae%20spectral-%5Cu00ad%20domain%20optical%20coherence%20tomography%20%28SD-%5Cu00adOCT%29%20in%20healthy%20German%20children%20and%20adolescents%20and%20investigate%20influencing%20factors.%5CnMethods%3A%20The%20cross-%5Cu00adsectional%20study%20included%20the%20right%20eye%20of%20695%20children%20with%20at%20least%20one%20complete%20retinal%20OCT%20scan.%20As%20part%20of%20the%20LIFE%20Child%20study%2C%20the%20children%20underwent%20an%20ophthalmological%20examination%20including%20axial%20length%20%28AL%29%2C%20spherical%20equivalent%20%28SE%29%20and%20OCT%20measurements.%20Various%20questionnaires%20were%20answered%20by%20the%20children%20or%20their%20parents%20to%20identify%20media%20use%20or%20outdoor%20time.%20Multiple%20linear%20regression%20models%20were%20used%20to%20investigate%20the%20potential%20influencing%20factors.%5CnResults%3A%20A%20total%20of%20342%20boys%20and%20353%20girls%20with%20an%20average%20age%20%28SD%29%20of%2012.91%20%283.29%29%20years%20participated.%20The%20mean%20AL%20%28SD%29%20was%2023.20%20%280.86%29%20mm.%20The%20mean%20macular%20thickness%20%28SD%29%20was%20320.53%20%2812.29%29%20%5Cu03bcm%20and%20the%20mean%20RNFL%20thickness%20%28SD%29%20was%20102.88%20%288.79%29%20%5Cu03bcm.%20Statistical%20analysis%20revealed%20a%20significant%20correlation%20between%20average%20macular%20thickness%20and%20age%20%28p%5Cu2009%3C%5Cu20090.001%2C%20%5Cu03b2%20%3D%200.77%29%20as%20well%20as%20AL%20%28p%5Cu2009%3C%5Cu20090.001%2C%20%5Cu03b2%20%3D%20%5Cu22124.06%29.%20In%20addition%2C%20boys%20had%20thicker%20maculae%20%28p%5Cu2009%3C%5Cu20090.001%2C%20%5Cu03b2%20%3D%205.36%29.%20The%20RNFL%20thickness%20showed%20no%20significant%20correlation%20with%20children%27s%20age%20%28p%5Cu2009%3E%5Cu20090.05%29%2C%20but%20with%20AL%20%28p%20%3D%200.002%2C%20%5Cu03b2%20%3D%20%5Cu22122.15%29%2C%20birth%20weight%20%28p%20%3D%200.02%2C%20%5Cu03b2%20%3D%200.003%29%20and%20a%20gender-%5Cu00adspecific%20effect%20of%20the%20body%20mass%20index%20standard%20deviation%20score%20for%20male%20participants%20%28p%20%3D%200.02%2C%20%5Cu03b2%20%3D%201.93%29.%5CnConclusion%3A%20This%20study%20provides%20normative%20data%20and%20correlations%20between%20macular%20and%20RNFL%20thickness%20in%20healthy%20German%20children.%20Especially%20age%2C%20gender%20and%20AL%20must%20be%20taken%20into%20account%20when%20evaluating%20quantitative%20OCT%20measurements%20to%20classify%20them%20as%20normal.%22%2C%22date%22%3A%222023-03-17%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1111%5C%2Fopo.13123%22%2C%22ISSN%22%3A%220275-5408%2C%201475-1313%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fonlinelibrary.wiley.com%5C%2Fdoi%5C%2F10.1111%5C%2Fopo.13123%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222024-08-27T13%3A11%3A16Z%22%7D%7D%2C%7B%22key%22%3A%2298ACU36I%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Dathan-Stumpf%20et%20al.%22%2C%22parsedDate%22%3A%222023-03-02%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EDathan-Stumpf%2C%20Anne%2C%20Mandy%20Vogel%2C%20Nico%20Grafe%2C%20Wieland%20Kiess%2C%20and%20Holger%20Stepan.%20%26%23x201C%3BRelation%20between%20Socioeconomic%20Status%20and%20Maternal%20Serum%20Lipids%20to%20Infant%20Lipid%20Concentrations%20and%20Anthropometry%20in%20the%20First%20Year%20of%20Life.%26%23x201D%3B%20%3Ci%3EArchives%20of%20Gynecology%20and%20Obstetrics%3C%5C%2Fi%3E%2C%20March%202%2C%202023.%20%3Ca%20class%3D%27zp-ItemURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs00404-023-06937-6%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs00404-023-06937-6%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Relation%20between%20socioeconomic%20status%20and%20maternal%20serum%20lipids%20to%20infant%20lipid%20concentrations%20and%20anthropometry%20in%20the%20first%20year%20of%20life%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anne%22%2C%22lastName%22%3A%22Dathan-Stumpf%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Nico%22%2C%22lastName%22%3A%22Grafe%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Holger%22%2C%22lastName%22%3A%22Stepan%22%7D%5D%2C%22abstractNote%22%3A%22The%20physical%20health%20and%20development%20of%20an%20individual%20are%20influenced%20by%20multiple%20parameters%20and%20shaped%20by%20internal%20and%20external%20factors%20during%20pregnancy.%20However%2C%20it%20is%20unclear%20whether%20there%20is%20an%20association%20between%20maternal%20lipid%20concentrations%20in%20the%20third%20trimester%20of%20pregnancy%20and%20infant%20serum%20lipids%20as%20well%20as%20anthropometric%20growth%2C%20and%20whether%20these%20factors%20are%20influenced%20by%20the%20socioeconomic%20status%20%28SES%29%20of%20the%20mothers.%22%2C%22date%22%3A%222023-03-02%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1007%5C%2Fs00404-023-06937-6%22%2C%22ISSN%22%3A%221432-0711%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs00404-023-06937-6%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-23T12%3A21%3A59Z%22%7D%7D%2C%7B%22key%22%3A%22QU74DC8K%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Poulain%20et%20al.%22%2C%22parsedDate%22%3A%222023-02-21%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EPoulain%2C%20Tanja%2C%20Christof%20Meigen%2C%20Wieland%20Kiess%2C%20and%20Mandy%20Vogel.%20%26%23x201C%3BMedia%20Regulation%20Strategies%20in%20Parents%20of%204-%20to%2016-Year-Old%20Children%20and%20Adolescents%3A%20A%20Cross-Sectional%20Study.%26%23x201D%3B%20%3Ci%3EBMC%20Public%20Health%3C%5C%2Fi%3E%2023%2C%20no.%201%20%28February%2021%2C%202023%29%3A%20371.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs12889-023-15221-w%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs12889-023-15221-w%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Media%20regulation%20strategies%20in%20parents%20of%204-%20to%2016-year-old%20children%20and%20adolescents%3A%20a%20cross-sectional%20study%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christof%22%2C%22lastName%22%3A%22Meigen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%5D%2C%22abstractNote%22%3A%22BACKGROUND%3A%20Since%20children%20can%20only%20control%20and%20limit%20their%20own%20media%20use%20to%20a%20limited%20extent%2C%20it%20is%20often%20the%20parents%20who%20regulate%20their%20children%27s%20media%20use.%20However%2C%20there%20is%20insufficient%20research%20on%20which%20strategies%20they%20use%20and%20on%20how%20these%20strategies%20are%20related%20to%20socio-demographic%20and%20behavioral%20parameters.%5CnMETHODS%3A%20The%20parental%20media%20regulation%20strategies%20co-use%2C%20active%20mediation%2C%20restrictive%20mediation%2C%20monitoring%2C%20and%20technical%20mediation%20were%20assessed%20in%20a%20sample%20of%20563%20four-%20to%2016-year-old%20children%20and%20adolescents%20from%20middle%20to%20high%20social%20strata%20participating%20in%20the%20German%20cohort%20study%20LIFE%20Child.%20We%20investigated%20cross-sectional%20associations%20with%20socio-demographic%20characteristics%20%28age%20and%20sex%20of%20child%2C%20age%20of%20parent%2C%20and%20socio-economic%20status%20%28SES%29%29%20and%20other%20behavioral%20parameters%20of%20children%20%28media%20use%2C%20ownership%20of%20media%20devices%2C%20engagement%20in%20extracurricular%20activities%29%20and%20their%20parents%20%28media%20use%29.%5CnRESULTS%3A%20All%20media%20regulation%20strategies%20were%20applied%20frequently%2C%20with%20restrictive%20mediation%20occurring%20most%20frequently.%20Overall%2C%20parents%20of%20younger%20children%20and%20of%20boys%20mediated%20media%20use%20more%20frequently%2C%20while%20we%20observed%20no%20differences%20depending%20on%20SES.%20Regarding%20child%20behavior%2C%20the%20ownership%20of%20a%20smartphone%20and%20a%20tablet%5C%2Fpersonal%20computer%5C%2Flaptop%20was%20associated%20with%20more%20frequent%20technical%20restriction%2C%20while%20screen%20time%20and%20engagement%20in%20extracurricular%20activities%20was%20not%20associated%20with%20parental%20media%20regulation.%20In%20contrast%2C%20parental%20screen%20time%20was%20related%20to%20more%20frequent%20co-use%20and%20less%20frequent%20use%20of%20restrictive%20and%20technical%20mediation.%5CnCONCLUSION%3A%20Parental%20regulation%20of%20child%20media%20use%20is%20influenced%20by%20parental%20attitudes%20and%20a%20perceived%20need%20for%20mediation%20%28e.g.%2C%20in%20younger%20children%20or%20children%20owning%20internet-enabled%20devices%29%20rather%20than%20child%20behavior.%22%2C%22date%22%3A%222023-02-21%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1186%5C%2Fs12889-023-15221-w%22%2C%22ISSN%22%3A%221471-2458%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-24T11%3A01%3A01Z%22%7D%7D%2C%7B%22key%22%3A%22MHNAXU6I%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Herzig%20et%20al.%22%2C%22parsedDate%22%3A%222023-02-16%22%2C%22numChildren%22%3A2%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EHerzig%2C%20Markus%2C%20Astrid%20Bertsche%2C%20Cornelia%20Hilbert%2C%20Wieland%20Kiess%2C%20Thilo%20Bertsche%2C%20and%20Martina%20Patrizia%20Neininger.%20%26%23x201C%3BPharmacoepidemiological%20Analysis%20of%20Oral%20Contraceptive%20Use%20in%20Adolescents%20in%20a%20German%20Longitudinal%20Cohort%20Study.%26%23x201D%3B%20%3Ci%3EChildren%20%28Basel%2C%20Switzerland%29%3C%5C%2Fi%3E%2010%2C%20no.%202%20%28February%2016%2C%202023%29%3A%20393.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Fchildren10020393%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Fchildren10020393%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Pharmacoepidemiological%20Analysis%20of%20Oral%20Contraceptive%20Use%20in%20Adolescents%20in%20a%20German%20Longitudinal%20Cohort%20Study%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Markus%22%2C%22lastName%22%3A%22Herzig%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Astrid%22%2C%22lastName%22%3A%22Bertsche%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Cornelia%22%2C%22lastName%22%3A%22Hilbert%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Thilo%22%2C%22lastName%22%3A%22Bertsche%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Martina%20Patrizia%22%2C%22lastName%22%3A%22Neininger%22%7D%5D%2C%22abstractNote%22%3A%22To%20assess%20the%20use%20of%20oral%20contraceptives%20%28OC%29%20in%20adolescents%2C%20using%20data%20from%20a%20longitudinal%2C%20population-based%20pediatric%20cohort%20study%20%28LIFE%20Child%29.%20We%20also%20investigated%20associations%20between%20OC%20use%20and%20socioeconomic%20status%20%28SES%29%2C%20and%20associations%20between%20OC%20use%20and%20potential%20adverse%20drug%20reactions%20such%20as%20effects%20on%20blood%20pressure.%20We%20included%20609%20female%20participants%20of%20the%20LIFE%20Child%20cohort%2C%20aged%20%5Cu226513%20to%20%3C21%20years%2C%20who%20visited%20the%20study%20center%20between%202012%20and%202019.%20Data%20collection%20compromised%20drug%20use%20in%20the%20past%2014%20days%2C%20SES%2C%20and%20anthropometric%20data%20such%20as%20blood%20pressure.%20An%20analysis%20of%20covariance%20was%20used%20to%20detect%20potential%20associations%20between%20participants%27%20blood%20pressure%20and%20OC.%20Multivariate%20binary%20logistic%20regression%20was%20used%20to%20obtain%20odds%20ratios%20%28aOR%29%20adjusted%20for%20age%20and%2095%25%20confidence%20intervals%20%2895%25%20CI%29.%20The%20prevalence%20of%20OC%20use%20was%2025.8%25.%20OC%20intake%20was%20less%20common%20in%20participants%20with%20a%20high%20SES%20%28aOR%200.30%2C%2095%25%20CI%200.15%2C%200.62%29.%20The%20mean%20age%20at%20OC%20initiation%20did%20not%20change%20between%202012%20and%202019.%20We%20observed%20an%20increased%20use%20of%20second-generation%20OC%20%282013%3A%2017.9%25%2C%202019%3A%2048.5%25%3B%20p%20%3D%200.013%29%20and%20a%20decreased%20use%20of%20fourth-generation%20OC%20%282013%3A%2071.8%25%2C%202019%3A%2045.5%25%3B%20p%20%3D%200.027%29.%20We%20found%20a%20higher%20systolic%20%28mean%3A%20111.74%20mmHg%2C%20p%20%3C%200.001%29%20and%20diastolic%20%2869.15%20mmHg%2C%20p%20%3D%200.004%29%20blood%20pressure%20in%20OC%20users%20compared%20to%20non-users%20%28systolic%3A%20108.60%20mmHg%3B%20diastolic%3A%2067.24%20mmHg%29.%20Every%20fourth%20adolescent%20took%20an%20OC.%20The%20share%20of%20second-generation%20OC%20increased%20during%20the%20study%20period.%20OC%20intake%20was%20associated%20with%20low%20SES.%20OC%20users%20had%20a%20slightly%20higher%20blood%20pressure%20than%20non-users.%22%2C%22date%22%3A%222023-02-16%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.3390%5C%2Fchildren10020393%22%2C%22ISSN%22%3A%222227-9067%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-27T08%3A23%3A39Z%22%7D%7D%2C%7B%22key%22%3A%22KL5QE2N4%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22F%5Cu00f6rster%20et%20al.%22%2C%22parsedDate%22%3A%222023-01-19%22%2C%22numChildren%22%3A2%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EF%26%23xF6%3Brster%2C%20Lucas-Johann%2C%20Mandy%20Vogel%2C%20Robert%20Stein%2C%20Anja%20Hilbert%2C%20Julius%20Lars%20Breinker%2C%20Marleen%20B%26%23xF6%3Bttcher%2C%20Wieland%20Kiess%2C%20and%20Tanja%20Poulain.%20%26%23x201C%3BMental%20Health%20in%20Children%20and%20Adolescents%20with%20Overweight%20or%20Obesity.%26%23x201D%3B%20%3Ci%3EBMC%20Public%20Health%3C%5C%2Fi%3E%2023%2C%20no.%201%20%28January%2019%2C%202023%29%3A%20135.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs12889-023-15032-z%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs12889-023-15032-z%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Mental%20health%20in%20children%20and%20adolescents%20with%20overweight%20or%20obesity%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Lucas-Johann%22%2C%22lastName%22%3A%22F%5Cu00f6rster%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Robert%22%2C%22lastName%22%3A%22Stein%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anja%22%2C%22lastName%22%3A%22Hilbert%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Julius%20Lars%22%2C%22lastName%22%3A%22Breinker%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Marleen%22%2C%22lastName%22%3A%22B%5Cu00f6ttcher%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%5D%2C%22abstractNote%22%3A%22BACKGROUND%3A%20Overweight%20and%20obesity%20represent%20huge%20concerns%20for%20children%27s%20physical%20and%20mental%20well-being.%20This%20study%20examined%20the%20relationship%20between%20body%20mass%20index%20%28BMI%29%20and%20health-related%20quality%20of%20life%20%28HRQoL%29%2C%20somatoform%20complaints%2C%20and%20behavioral%20problems%20in%20children%20and%20adolescents.%20Additionally%2C%20the%20influence%20of%20sex%2C%20age%2C%20and%20socioeconomic%20status%20%28SES%29%20on%20these%20associations%20was%20considered.%5CnMETHODS%3A%20In%20total%2C%20we%20studied%202350%20participants%20between%20the%20ages%20of%204%20and%2018%20years%20%281213%204-%20to%2010-years-old%20%28child%20sample%29%20and%201137%2011-to%2018-year-olds%20%28adolescent%20sample%29%29.%20To%20assess%20HRQoL%2C%20somatoform%20complaints%2C%20and%20behavioral%20difficulties%2C%20we%20applied%20the%20KIDSCREEN-27%2C%20a%20short%20form%20of%20the%20Giessen%20Complaints%20Questionnaire%2C%20and%20the%20Strengths%20and%20Difficulties%20Questionnaire%20%28SDQ%29.%20The%20BMI%20was%20transformed%20to%20BMI%20standard%20deviation%20scores%20%28BMI-SDS%29%2C%20according%20to%20German%20gender-%20and%20age-specific%20reference%20data.%20Associations%20were%20investigated%20using%20linear%20regression%20analyses.%20Each%20association%20was%20checked%20for%20interaction%20with%20sex%2C%20age%2C%20and%20SES.%5CnRESULTS%3A%20Regarding%20HRQoL%2C%20we%20found%20worsening%20scores%20in%20physical%20well-being%20and%20psychological%20well-being%20with%20increasing%20BMI-SDS.%20Somatoform%20complaints%20were%20not%20significantly%20associated%20with%20BMI-SDS.%20Conduct%20problems%2C%20peer%20relationship%20problems%2C%20and%20emotional%20problems%20%28the%20latter%20only%20in%20the%20adolescent%20sample%29%20were%20positively%20associated%20with%20BMI-SDS.%20While%20we%20did%20not%20observe%20any%20significant%20interactions%20with%20sex%2C%20we%20found%20some%20significant%20interactions%20with%20age%20and%5C%2For%20SES.%5CnCONCLUSION%3A%20Our%20findings%20highlight%20the%20importance%20of%20mental%20difficulties%20in%20children%20and%20adolescents%20with%20higher%20BMI%20and%2C%20consequently%2C%20underline%20the%20relevance%20of%20including%20psychological%20interventions%20in%20the%20treatment%20of%20overweight%20or%20obesity.%22%2C%22date%22%3A%222023-01-19%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1186%5C%2Fs12889-023-15032-z%22%2C%22ISSN%22%3A%221471-2458%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-21T12%3A08%3A50Z%22%7D%7D%2C%7B%22key%22%3A%228N4SQW66%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Roth%20et%20al.%22%2C%22parsedDate%22%3A%222023-01-06%22%2C%22numChildren%22%3A2%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3ERoth%2C%20Anna%2C%20Christof%20Meigen%2C%20Andreas%20Hiemisch%2C%20Wieland%20Kiess%2C%20and%20Tanja%20Poulain.%20%26%23x201C%3BAssociations%20between%20Stressful%20Life%20Events%20and%20Increased%20Physical%20and%20Psychological%20Health%20Risks%20in%20Adolescents%3A%20A%20Longitudinal%20Study.%26%23x201D%3B%20%3Ci%3EInternational%20Journal%20of%20Environmental%20Research%20and%20Public%20Health%3C%5C%2Fi%3E%2020%2C%20no.%202%20%28January%206%2C%202023%29%3A%201050.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Fijerph20021050%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Fijerph20021050%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Associations%20between%20Stressful%20Life%20Events%20and%20Increased%20Physical%20and%20Psychological%20Health%20Risks%20in%20Adolescents%3A%20A%20Longitudinal%20Study%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anna%22%2C%22lastName%22%3A%22Roth%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christof%22%2C%22lastName%22%3A%22Meigen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andreas%22%2C%22lastName%22%3A%22Hiemisch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%5D%2C%22abstractNote%22%3A%22Stressful%20life%20events%20%28SLEs%29%20are%20understood%20as%20risk%20factors%20for%20mental%20and%20physical%20health%20problems%2C%20particularly%20in%20the%20vulnerable%20period%20of%20adolescence.%20Using%20a%20longitudinal%20approach%2C%20this%20study%20investigated%20associations%20between%20SLE%20and%20several%20negative%20health%20outcomes%20in%20adolescents.%20Moderating%20effects%20of%20sociodemographic%20factors%20were%20considered.%20We%20analyzed%20the%20data%20of%20a%20healthy%20adolescent%20sample%20from%20the%20LIFE%20Child%20study%20in%20Leipzig%2C%20Germany%20%28n%20%3D%202024%2C%20aged%2010-18%20years%29.%20SLEs%20were%20measured%20by%20a%20questionnaire%2C%20addressing%20SLEs%20in%20the%20family%20and%20the%20social%20environment%20domain.%20Health-related%20quality%20of%20life%20%28HrQoL%29%2C%20behavioral%20difficulties%20and%20BMI%20were%20compared%20before%20and%20after%20an%20SLE%20had%20occurred.%20Moderator%20effects%20of%20socioeconomic%20status%20%28SES%29%2C%20age%2C%20and%20sex%20were%20investigated%20using%20linear%20regression%20models.%20All%20considered%20health%20parameters%20had%2C%20on%20average%2C%20deteriorated%20after%20the%20occurrence%20of%20an%20SLE%20in%20the%20social%20environment.%20Differences%20in%20HrQoL%20before%20and%20after%20an%20SLE%20were%20significantly%20stronger%20in%20girls.%20Higher%20SES%20functioned%20as%20a%20slight%20protective%20factor%20against%20decreased%20well-being%20after%20an%20SLE.%20The%20findings%20suggest%20that%20SLEs%20function%20as%20risk%20factors%20for%20mental%20and%20physical%20health%20disadvantages%20in%20adolescents.%20Prevention%20programs%20should%20seek%20to%20support%20adolescents%20in%20all%20age%20and%20SES%20groups%20affected%20by%20SLEs%2C%20with%20a%20specific%20focus%20on%20girls.%22%2C%22date%22%3A%222023-01-06%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.3390%5C%2Fijerph20021050%22%2C%22ISSN%22%3A%221660-4601%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-27T08%3A49%3A51Z%22%7D%7D%2C%7B%22key%22%3A%22UDCNY4UG%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Stein%20et%20al.%22%2C%22parsedDate%22%3A%222023-01%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EStein%2C%20Robert%2C%20Florian%20Koutny%2C%20Johannes%20Riedel%2C%20Natascha%20D%26%23xF6%3Brr%2C%20Klara%20Meyer%2C%20Marco%20Colombo%2C%20Mandy%20Vogel%2C%20et%20al.%20%26%23x201C%3BSingle%20Point%20Insulin%20Sensitivity%20Estimator%20%28SPISE%29%20as%20a%20Prognostic%20Marker%20for%20Emerging%20Dysglycemia%20in%20Children%20with%20Overweight%20or%20Obesity.%26%23x201D%3B%20%3Ci%3EMetabolites%3C%5C%2Fi%3E%2013%2C%20no.%201%20%28January%202023%29%3A%20100.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Fmetabo13010100%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Fmetabo13010100%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Single%20Point%20Insulin%20Sensitivity%20Estimator%20%28SPISE%29%20as%20a%20Prognostic%20Marker%20for%20Emerging%20Dysglycemia%20in%20Children%20with%20Overweight%20or%20Obesity%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Robert%22%2C%22lastName%22%3A%22Stein%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Florian%22%2C%22lastName%22%3A%22Koutny%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Johannes%22%2C%22lastName%22%3A%22Riedel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Natascha%22%2C%22lastName%22%3A%22D%5Cu00f6rr%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Klara%22%2C%22lastName%22%3A%22Meyer%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Marco%22%2C%22lastName%22%3A%22Colombo%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christian%20Heinz%22%2C%22lastName%22%3A%22Anderwald%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Matthias%22%2C%22lastName%22%3A%22Bl%5Cu00fcher%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Daniel%22%2C%22lastName%22%3A%22Weghuber%22%7D%5D%2C%22abstractNote%22%3A%22The%20single%20point%20insulin%20sensitivity%20estimator%20%28SPISE%29%20is%20a%20recently%20developed%20fasting%20index%20for%20insulin%20sensitivity%20based%20on%20triglycerides%2C%20high%20density%20lipoprotein%20cholesterol%2C%20and%20body%20mass%20index.%20SPISE%20has%20been%20validated%20in%20juveniles%20and%20adults%3B%20still%2C%20its%20role%20during%20childhood%20remains%20unclear.%20To%20evaluate%20the%20age-%20and%20sex-specific%20distribution%20of%20SPISE%2C%20its%20correlation%20with%20established%20fasting%20indexes%20and%20its%20application%20as%20a%20prognostic%20marker%20for%20future%20dysglycemia%20during%20childhood%20and%20adolescence%20were%20assessed.%20We%20performed%20linear%20modeling%20and%20correlation%20analyses%20on%20a%20cross-sectional%20cohort%20of%202107%20children%20and%20adolescents%20%28age%205%20to%2018.4%20years%29%20with%20overweight%20or%20obesity.%20Furthermore%2C%20survival%20analyses%20were%20conducted%20upon%20a%20longitudinal%20cohort%20of%20591%20children%20with%20overweight%5C%2Fobesity%20%281712%20observations%29%20with%20a%20maximum%20follow-up%20time%20of%20nearly%2020%20years%2C%20targeting%20prediabetes%5C%2Fdysglycemia%20as%20the%20end%20point.%20The%20SPISE%20index%20decreased%20significantly%20with%20age%20%28%5Cu22120.34%20units%20per%20year%2C%20p%20%3C%200.001%29%20among%20children%20and%20adolescents%20with%20overweight%20and%20obesity.%20Sex%20did%20not%20have%20an%20influence%20on%20SPISE.%20There%20was%20a%20modest%20correlation%20between%20SPISE%20and%20established%20fasting%20markers%20of%20insulin%20resistance%20%28R%20%3D%20%5Cu22120.49%20for%20HOMA-IR%2C%20R%20%3D%20%5Cu22120.55%20for%20QUICKI-IR%29.%20SPISE%20is%20a%20better%20prognostic%20marker%20for%20future%20dysglycemia%20%28hazard%20ratio%20%28HR%29%203.47%2C%2095%25%20confidence%20interval%20%28CI%29%201.60%5Cu20137.51%2C%20p%20%3C%200.01%29%20than%20HOMA-IR%20and%20QUICKI-IR%20%28HR%202.44%2C%2095%25%20CI%201.24%5Cu20134.81%2C%20p%20%3C%200.05%29.%20The%20SPISE%20index%20is%20a%20surrogate%20marker%20for%20insulin%20resistance%20predicting%20emerging%20dysglycemia%20in%20children%20with%20overweight%20or%20obesity%2C%20and%20could%2C%20therefore%2C%20be%20applied%20to%20pediatric%20cohorts%20that%20lack%20direct%20insulin%20assessment.%22%2C%22date%22%3A%222023%5C%2F1%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.3390%5C%2Fmetabo13010100%22%2C%22ISSN%22%3A%222218-1989%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.mdpi.com%5C%2F2218-1989%5C%2F13%5C%2F1%5C%2F100%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222024-03-28T15%3A36%3A49Z%22%7D%7D%2C%7B%22key%22%3A%2283E3XT9F%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Hirsch%20et%20al.%22%2C%22parsedDate%22%3A%222023%22%2C%22numChildren%22%3A2%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EHirsch%2C%20Christian%2C%20Oliver%20Schierz%2C%20Antje%20K%26%23xF6%3Brner%2C%20Wieland%20Kiess%2C%20Ronald%20Biemann%2C%20Annett%20Schrock%2C%20and%20Jens%20Christoph%20T%26%23xFC%3Brp.%20%26%23x201C%3BSex%20Hormones%20Associated%20with%20Temporomandibular%20Pain%20on%20Palpation%20in%20Male%20Adolescents%26%23×2014%3BResults%20of%20the%20Epidemiologic%20LIFE%20Child%20Study.%26%23x201D%3B%20%3Ci%3EJournal%20of%20Oral%20Rehabilitation%3C%5C%2Fi%3E%20n%5C%2Fa%2C%20no.%20n%5C%2Fa%20%282023%29.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fjoor.13530%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fjoor.13530%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Sex%20hormones%20associated%20with%20temporomandibular%20pain%20on%20palpation%20in%20male%20adolescents%5Cu2014Results%20of%20the%20epidemiologic%20LIFE%20child%20study%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christian%22%2C%22lastName%22%3A%22Hirsch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Oliver%22%2C%22lastName%22%3A%22Schierz%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ronald%22%2C%22lastName%22%3A%22Biemann%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Annett%22%2C%22lastName%22%3A%22Schrock%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jens%20Christoph%22%2C%22lastName%22%3A%22T%5Cu00fcrp%22%7D%5D%2C%22abstractNote%22%3A%22Objective%20This%20study%20aimed%20to%20investigate%20whether%20the%20sex%20steroid%20precursor%20hormone%20dehydroepiandrosterone%20sulphate%20%28DHEA-S%29%2C%20sex%20hormone-binding%20globulin%20%28SHBG%29%20and%20testosterone%20%28TT%29%20are%20associated%20with%20temporomandibular%20%28TM%29%20pain%20on%20palpation%20in%20male%20adolescents.%20Methods%20Out%20of%20the%20LIFE%20Child%20study%20dataset%20containing%201022%20children%20and%20adolescents%20aged%2010%5Cu201318%20years%20%28496%20males%2C%2048.5%25%29%2C%20we%20used%20a%20subsample%20of%20273%20male%20adolescents%20%28mean%20age%3A%2013.8%20%5Cu00b1%202.3%20years%29%20in%20advanced%20pubertal%20development%20%28PD%29%20to%20analyse%20the%20association%20between%20hormones%20and%20TM%20pain.%20The%20Tanner%20scale%20was%20applied%20to%20describe%20the%20stage%20of%20PD.%20Pain%20on%20palpation%20of%20the%20temporalis%20and%20masseter%20muscles%20and%20the%20TM%20joints%20%28palpation%20pain%29%20was%20assessed%20using%20the%20Diagnostic%20Criteria%20for%20Temporomandibular%20Disorders%20%28DC%5C%2FTMD%29.%20Serum%20levels%20of%20sex%20hormones%20%28DHEA-S%2C%20SHBG%20and%20TT%29%20were%20determined%20using%20standardised%20laboratory%20analyses.%20Free%20TT%20was%20estimated%20from%20the%20ratio%20between%20TT%20and%20SHBG%20%28free%20androgen%20index%5BFAI%5D%29.%20We%20calculated%20the%20risk%20of%20perceived%20positive%20palpation%20pain%20for%20male%20participants%20as%20a%20function%20of%20hormone%20levels%20%28DHEA-S%2C%20FAI%29%20taking%20into%20account%20age%20and%20body%20mass%20index%20%28BMI%29.%20Results%20Among%20more%20developed%20%28Tanner%20stage%204%5Cu20135%29%20male%20adolescents%2C%2022.7%25%20%28n%20%3D%2062%29%20reported%20palpation%20pain%20in%20the%20TM%20region.%20In%20these%20participants%2C%20FAI%20levels%20were%20approximately%20half%20that%20of%20individuals%20without%20such%20pain%20%28p%20%3C%20.01%29.%20DHEA-S%20levels%20were%20about%2030%25%20lower%20in%20the%20pain%20group%20%28p%20%3C%20.01%29.%20In%20multivariable%20regression%20analyses%2C%20the%20odds%20ratio%20%28OR%29%20for%20pain%20on%20palpation%20decreased%20to%200.75%20%2895%25%20confidence%20interval%20%5BCI%5D%3A%200.57%5Cu20130.98%29%20per%2010%20units%20of%20FAI%20level%20compared%20to%20those%20without%20pain%2C%20after%20controlling%20for%20the%20effects%20of%20age%20and%20adjusted%20BMI.%20We%20observed%20the%20same%20effect%20for%20this%20subgroup%20per%20unit%20of%20DHEA-S%20serum%20level%20%28OR%20%3D%200.71%3B%2095%25%20CI%3A%200.53%5Cu20130.94%29.%20Conclusion%20At%20subclinical%20lower%20levels%20of%20serum%20free%20TT%20and%20DHEA-S%2C%20male%20adolescents%20are%20more%20likely%20to%20report%20pain%20on%20standardised%20palpation%20of%20the%20masticatory%20muscles%20and%5C%2For%20TM%20joints.%20This%20finding%20supports%20the%20hypothesis%20that%20sex%20hormones%20may%20influence%20pain%20reporting.%22%2C%22date%22%3A%222023%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1111%5C%2Fjoor.13530%22%2C%22ISSN%22%3A%221365-2842%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fonlinelibrary.wiley.com%5C%2Fdoi%5C%2Fabs%5C%2F10.1111%5C%2Fjoor.13530%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-24T08%3A49%3A13Z%22%7D%7D%2C%7B%22key%22%3A%22PIT7XYLR%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Schmidt%20et%20al.%22%2C%22parsedDate%22%3A%222022-12%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3ESchmidt%2C%20Ricarda%2C%20Andreas%20Hiemisch%2C%20Wieland%20Kiess%2C%20Kai%20von%20Klitzing%2C%20Franziska%20Schlensog-Schuster%2C%20and%20Anja%20Hilbert.%20%26%23x201C%3BValidation%20Study%20on%20the%20Child%2C%20Adult%2C%20and%20Parent%20Version%20of%20the%20ARFID%20Module%202.0%20for%20the%20Eating%20Disorder%20Examination.%26%23x201D%3B%20%3Ci%3EThe%20International%20Journal%20of%20Eating%20Disorders%3C%5C%2Fi%3E%2055%2C%20no.%2012%20%28December%202022%29%3A%201708%26%23×2013%3B20.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1002%5C%2Feat.23805%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1002%5C%2Feat.23805%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Validation%20study%20on%20the%20child%2C%20adult%2C%20and%20parent%20version%20of%20the%20ARFID%20module%202.0%20for%20the%20Eating%20Disorder%20Examination%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ricarda%22%2C%22lastName%22%3A%22Schmidt%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andreas%22%2C%22lastName%22%3A%22Hiemisch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Kai%22%2C%22lastName%22%3A%22von%20Klitzing%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Franziska%22%2C%22lastName%22%3A%22Schlensog-Schuster%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anja%22%2C%22lastName%22%3A%22Hilbert%22%7D%5D%2C%22abstractNote%22%3A%22OBJECTIVE%3A%20This%20study%20presents%20a%20psychometric%20evaluation%20of%20the%20avoidant%5C%2Frestrictive%20food%20intake%20disorder%20%28ARFID%29%20module%202.0%20for%20the%20Eating%20Disorder%20Examination%20%28EDE%29%2C%20its%20child%20%28ChEDE%29%2C%20and%20parent%20version.%20Within%20a%20pediatric%20sample%20seeking%20treatment%20for%20restrictive%20feeding%20or%20eating%20disorders%20and%20non-treatment-seeking%20controls%2C%20the%20module%27s%20interrater%20reliability%2C%20parent-child%20agreement%2C%20and%20its%20convergent%2C%20divergent%2C%20and%20discriminant%20validity%20were%20examined.%5CnMETHOD%3A%20The%20child%2C%20adult%2C%20and%5C%2For%20parent%20version%20of%20the%20German%20ARFID%20module%20was%20administered%20to%20N%5Cu00a0%3D%5Cu00a0176%20children%20and%20adolescents%20%280-17%5Cu2009years%29%20and%20their%20parents%2C%20as%20were%20the%20%28Ch%29EDE%2C%20well-established%20measures%20on%20food-avoidance%20behaviors%2C%20food%20variety%2C%20and%20body%20esteem%2C%20and%20objective%20anthropometric%20measures.%5CnRESULTS%3A%20Across%20all%20versions%20of%20the%20ARFID%20module%2C%20substantial%20to%20almost%20perfect%20interrater%20reliability%20was%20shown.%20Parent-child%20agreement%20for%20ARFID%20diagnosis%20was%20substantial.%20Based%20on%20medium-to-large%20associations%20between%20interview-assessed%20avoidant%5C%2Frestrictive%20food%20intake%20and%20questionnaire-assessed%20food-avoidance%20behaviors%2C%20food%20variety%2C%20and%20objective%20weight%20status%2C%20the%20module%20showed%20high%20convergent%20validity%2C%20especially%20for%20the%20child%20and%20parent%20version.%20Low%20associations%20of%20avoidant%5C%2Frestrictive%20food%20intake%20with%20weight%20and%20shape%20concern%20demonstrated%20divergent%20validity.%20Individuals%20with%20ARFID%20differed%20significantly%20from%20those%20with%20anorexia%20nervosa%20and%20individually%20matched%20controls%20in%20a%20range%20of%20clinical%20characteristics%2C%20indicating%20discriminant%20validity.%5CnDISCUSSION%3A%20This%20comprehensive%20validation%20supports%20the%20EDE%20ARFID%20module%20to%20be%20a%20valuable%20measure%20for%20the%20assessment%20and%20diagnosis%20of%20ARFID%20in%200-17-year-olds%20based%20on%20self-%20and%20parent-report.%20Validation%20of%20the%20ARFID%20module%20against%20other%20interview-based%20measures%20on%20ARFID%20and%20its%20evaluation%20in%20an%20adult%20sample%20are%20pending.%5CnPUBLIC%20SIGNIFICANCE%3A%20Based%20on%20good%20reliability%20and%20validity%20of%20the%20avoidant%5C%2Frestrictive%20food%20intake%20disorder%20%28ARFID%29%20module%20for%20the%20Eating%20Disorder%20Examination%20%28EDE%29%20in%20its%20child%2C%20adult%2C%20and%20parent%20version%2C%20the%20present%20study%20paves%20the%20way%20for%20the%20clinical%20and%20research%20use%20of%20the%20interview-based%20EDE%20ARFID%20module%20for%20assessing%20ARFID%20across%20childhood%20and%20adolescence.%22%2C%22date%22%3A%222022-12%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1002%5C%2Feat.23805%22%2C%22ISSN%22%3A%221098-108X%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-24T11%3A24%3A41Z%22%7D%7D%2C%7B%22key%22%3A%22SRQN35UR%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Pf%5Cu00e4ffle%20et%20al.%22%2C%22parsedDate%22%3A%222022-11-25%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EPf%26%23xE4%3Bffle%2C%20Roland%2C%20Matthias%20Kn%26%23xFC%3Bpfer%2C%20Melanie%20G%26%23xF6%3Bbert%2C%20Mandy%20Vogel%2C%20Ruth%20Gausche%2C%20Christoph%20Beger%2C%20Eberhard%20Keller%2C%20Antje%20K%26%23xF6%3Brner%2C%20Ulrich%20Thome%2C%20and%20Wieland%20Kiess.%20%26%23x201C%3BGrowth%20Patterns%20of%20Children%20With%20Short%20Stature%20in%20Adulthood%20According%20to%20Auxological%20Status%20and%20Maturity%20at%20Birth.%26%23x201D%3B%20%3Ci%3EThe%20Journal%20of%20Clinical%20Endocrinology%20and%20Metabolism%3C%5C%2Fi%3E%20107%2C%20no.%2012%20%28November%2025%2C%202022%29%3A%203320%26%23×2013%3B27.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F2022112511292049000%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F2022112511292049000%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Growth%20Patterns%20of%20Children%20With%20Short%20Stature%20in%20Adulthood%20According%20to%20Auxological%20Status%20and%20Maturity%20at%20Birth%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Roland%22%2C%22lastName%22%3A%22Pf%5Cu00e4ffle%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Matthias%22%2C%22lastName%22%3A%22Kn%5Cu00fcpfer%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Melanie%22%2C%22lastName%22%3A%22G%5Cu00f6bert%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ruth%22%2C%22lastName%22%3A%22Gausche%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christoph%22%2C%22lastName%22%3A%22Beger%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Eberhard%22%2C%22lastName%22%3A%22Keller%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ulrich%22%2C%22lastName%22%3A%22Thome%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%5D%2C%22abstractNote%22%3A%22CONTEXT%3A%20Prematurity%20carries%20a%20risk%20for%20impaired%20postnatal%20growth%20and%20long-term%20growth%20restriction.%20Especially%20children%20born%20SGA%20seem%20vulnerable%20for%20poor%20growth%2C%20as%20a%20persistent%20short%20stature%20can%20be%20observed%20in%20app%2010-15%25%20of%20these%20children.%5CnOBJECTIVE%3A%20In%20this%20study%20we%20aimed%20to%20recognize%20differences%20in%20growth%20patterns%20of%20children%20according%20to%20sex%2C%20maturity%2C%20and%20auxological%20status%20at%20birth%20facilitating%20earlier%20identification%20of%20small-for-gestational-age%20%28SGA%29%20children%20with%20adult%20short%20stature.%5CnMETHODS%3A%20The%20growth%20data%20of%2044%5Cu2005791%20infants%20born%20between%20January%201%2C%201980%2C%20and%20December%2030%2C%202012%2C%20among%202%20pediatric%20cohorts%20with%20follow-up%20through%20December%2031%2C%202020%2C%20were%20analyzed.%20A%20total%20of%205698%20children%20with%20birth%20data%20had%20measurements%20at%20near%20final%20height%20%28nfh%29%20and%20at%20least%202%20further%20points.%5CnRESULTS%3A%20Preterm%20children%20%28gestational%20age%20%3C%5Cu200537%20weeks%29%20had%20a%20significantly%20lower%20mean%20nfh%20SDS%20than%20term%20children%20%28preterm%2C%20-0.61%3B%20term%2C%20-0.18%29%20and%20a%20higher%20likelihood%20of%20nfh%20%3C%5Cu2005third%20percentile%20%28preterm%2C%2020.5%25%3B%20term%2C%2012.2%25%29.%20SGA%20born%20children%20also%20had%20a%20lower%20mean%20nfh%20SD%20score%20%28SDS%29%20than%20children%20born%20appropriate%20for%20gestational%20age%20%28AGA%29%20%28SGA%2C%20-1.06%3B%20AGA%2C%20-0.15%29%20and%20a%20higher%20likelihood%20of%20nfh%20%3C%5Cu2005third%20percentile%20%28SGA%2C%2028.2%25%3B%20AGA%2010.1%25%29.%20Of%201204%20SGA%20children%2C%20672%20%2856%25%29%20showed%20successful%20catch-up%20growth%20%28CUG%29%20to%20nfh%20greater%20than%20or%20equal%20to%20the%2010th%20percentile%20%28SGA-CU%29%2C%20and%20532%20children%20%2844%25%29%20did%20not%20%28SGA-S%29.%20The%20difference%20in%20their%20mean%20nfh%20SDS%20%28SGA-CU%2C%20-0.12%3B%20SGA-S%20-2.26%29%20can%20only%20partly%20be%20explained%20by%20the%20differences%20in%20mean%20mid-parental%20height%20SDS%20%28SGA-CU%2C%20-0.3%3B%20SGA-S%2C%20-1.19%29.%20During%20the%20first%20year%2C%20SGA-CU%20showed%20higher%20CUG%20%28SGA-CU%2C%20%2B1.2%20SDS%3B%20SGA-S%2C%20%2B0.45%20SDS%29%2C%20which%20helps%20to%20discriminate%20between%20groups%20earlier.%5CnCONCLUSION%3A%20Final%20growth%20outcome%20was%20influenced%20by%20prematurity%20and%20auxological%20status%20at%20birth%2C%20but%20not%20by%20sex.%20Height%5C%2Flength%20SDS%20increments%20during%20year%201%20are%20instrumental%20to%20discern%20SGA%20children%20with%20later%20normal%20or%20short%20stature.%20While%20observing%20CUG%20until%20year%202%20and%203%20can%20add%20specificity%2C%20discrimination%20thereafter%20becomes%20difficult.%22%2C%22date%22%3A%222022-11-25%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%222022112511292049000%22%2C%22ISSN%22%3A%221945-7197%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222024-08-27T13%3A13%3A14Z%22%7D%7D%2C%7B%22key%22%3A%22J6B8PXY7%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Philipp%20et%20al.%22%2C%22parsedDate%22%3A%222022-11-10%22%2C%22numChildren%22%3A2%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EPhilipp%2C%20Dariusch%2C%20Mandy%20Vogel%2C%20Manuela%20Brandt%2C%20Franziska%20G.%20Rauscher%2C%20Andreas%20Hiemisch%2C%20Siegfried%20Wahl%2C%20Wieland%20Kiess%2C%20and%20Tanja%20Poulain.%20%26%23x201C%3BThe%20Relationship%20between%20Myopia%20and%20near%20Work%2C%20Time%20Outdoors%20and%20Socioeconomic%20Status%20in%20Children%20and%20Adolescents.%26%23x201D%3B%20%3Ci%3EBMC%20Public%20Health%3C%5C%2Fi%3E%2022%2C%20no.%201%20%28November%2010%2C%202022%29%3A%202058.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs12889-022-14377-1%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs12889-022-14377-1%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22The%20relationship%20between%20myopia%20and%20near%20work%2C%20time%20outdoors%20and%20socioeconomic%20status%20in%20children%20and%20adolescents%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Dariusch%22%2C%22lastName%22%3A%22Philipp%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Manuela%22%2C%22lastName%22%3A%22Brandt%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Franziska%20G.%22%2C%22lastName%22%3A%22Rauscher%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andreas%22%2C%22lastName%22%3A%22Hiemisch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Siegfried%22%2C%22lastName%22%3A%22Wahl%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%5D%2C%22abstractNote%22%3A%22BACKGROUND%3A%20To%20investigate%20environmental%20and%20social%20risk%20factors%20for%20myopia%20in%20children%20and%20adolescents%20in%20Germany.%5CnMETHODS%3A%201437%20children%20aged%20between%203%20and%2018%20inclusive%20were%20examined%20as%20part%20of%20the%20LIFE%20Child%20study%20based%20in%20Leipzig%2C%20Germany.%20Information%20about%20leisure%20time%20activities%20and%20social%20status%20was%20ascertained%20by%20parents%20and%20children%20in%20a%20questionnaire.%20Refractive%20status%20was%20attained%20by%20measuring%20noncycloplegic%20autorefraction.%20Myopia%20was%20defined%20as%20spherical%20equivalent%20%28SE%29%5Cu2009%5Cu2264%5Cu2009-%5Cu20090.75%20D.%20Risk%20factors%20were%20identified%20using%20multiple%20logistic%20regression%20analysis.%5CnRESULTS%3A%20In%20multiple%20logistic%20regression%20analysis%2C%20myopia%20was%20significantly%20associated%20with%20less%20frequent%20outdoor%20activity%20%28%5C%22once%20a%20week%5C%22%20vs.%20%5C%22twice%20a%20week%20or%20more%5C%22%3A%20odds%20ratio%20%28OR%29%204.35%2C%2095%25%20confidence%20interval%20%28CI%29%201.89-9.98%2C%20p%26lt%3B0.01%29%20and%20longer%20near%20work%20sessions%20%281-2%5Cu00a0h%20vs.%20%26lt%3B%201%5Cu00a0h%3A%20OR%201.83%2C%20CI%201.10-3.04%2C%20p%3D0.02%3B%20%26gt%3B%203%5Cu00a0h%20vs.%20%26lt%3B%201%5Cu00a0h%3A%20OR%203.71%2C%20CI%201.43-9.61%2C%20p%26lt%3B0.01%29%20after%20adjustment%20for%20age%2C%20sex%20and%20socioeconomic%20status%20%28SES%29.%20Duration%20of%20outdoor%20activity%2C%20near%20work%20frequency%20and%20SES%20showed%20no%20significant%20association%20with%20myopia%20%28p%5Cu2009%26gt%3B%5Cu20090.05%29.%20Children%20with%20a%20lower%20SES%20were%20involved%20in%20longer%20periods%20of%20outdoor%20and%20near%20work%20activities%20but%20on%20fewer%20occasions%20over%20the%20course%20of%20the%20week%2C%20although%20this%20connection%20was%20not%20significant.%5CnCONCLUSION%3A%20Myopia%20is%20associated%20with%20environmental%20factors.%20The%20present%20findings%20suggest%20that%20daily%20exposure%20to%20sunlight%20and%20a%20restriction%20of%20long-duration%20near%20work%20activities%20might%20protect%20against%20pathological%20eye%20growth.%20Prevention%20strategies%20should%20be%20implemented%20for%20children%20at%20all%20ages.%22%2C%22date%22%3A%222022-11-10%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1186%5C%2Fs12889-022-14377-1%22%2C%22ISSN%22%3A%221471-2458%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222024-08-27T13%3A13%3A26Z%22%7D%7D%2C%7B%22key%22%3A%22BDD7FQLL%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Schild%20et%20al.%22%2C%22parsedDate%22%3A%222022-11-01%22%2C%22numChildren%22%3A2%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3ESchild%2C%20Clara%20Elise%2C%20Christof%20Meigen%2C%20Jonas%20Kappelt%2C%20Wieland%20Kiess%2C%20and%20Tanja%20Poulain.%20%26%23x201C%3BAssociations%20between%20Sociodemographic%20and%20Behavioural%20Parameters%20and%20Child%20Development%20Depending%20on%20Age%20and%20Sex%3A%20A%20Cross-Sectional%20Analysis.%26%23x201D%3B%20%3Ci%3EBMJ%20Open%3C%5C%2Fi%3E%2012%2C%20no.%2011%20%28November%201%2C%202022%29%3A%20e065936.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1136%5C%2Fbmjopen-2022-065936%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1136%5C%2Fbmjopen-2022-065936%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Associations%20between%20sociodemographic%20and%20behavioural%20parameters%20and%20child%20development%20depending%20on%20age%20and%20sex%3A%20a%20cross-sectional%20analysis%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Clara%20Elise%22%2C%22lastName%22%3A%22Schild%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christof%22%2C%22lastName%22%3A%22Meigen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jonas%22%2C%22lastName%22%3A%22Kappelt%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%5D%2C%22abstractNote%22%3A%22Objectives%20To%20explore%20environmental%20and%20individual%20factors%20that%20are%20associated%20with%20child%20development%20and%20to%20investigate%20whether%20the%20strength%20of%20these%20associations%20differs%20according%20to%20the%20age%20of%20the%20children.%5CnDesign%20Cross-sectional%20study.%5CnSetting%20This%20study%20was%20part%20of%20the%20LIFE%20Child%20study%2C%20a%20large%20cohort%20study%20conducted%20in%20Leipzig%2C%20Germany.%5CnParticipants%20778%20children%20aged%20between%200.5%20and%206%20years%20%2848.6%25%20girls%2C%20mean%20age%3D2.67%20years%29.%5CnOutcome%20measures%20The%20outcomes%20were%20cognitive%20development%2C%20language%20development%2C%20body%20and%20hand%20motor%20skills%2C%20social-emotional%20development%2C%20and%20tracing%20skills%2C%20measured%20with%20a%20standardised%20development%20test.%20We%20analysed%20the%20associations%20between%20development%20and%20gestational%20age%2C%20socioeconomic%20status%20%28SES%29%2C%20sex%2C%20behavioural%20difficulties%2C%20siblings%2C%20sleep%20duration%2C%20breastfeeding%20duration%20and%20overweight%5C%2Fobesity.%20We%20also%20tested%20for%20interactions%20between%20these%20variables%20and%20child%20age%20or%20sex.%5CnResults%20Higher%20gestational%20age%20%28b%20ranging%20between%200.12%20and%200.26%29%20and%20higher%20SES%20%28b%20ranging%20between%200.08%20and%200.21%29%20were%20associated%20with%20better%20outcomes%20in%20almost%20all%20developmental%20domains%20%28all%20p%3C0.019%29.%20Children%20with%20older%20siblings%20had%20improved%20body%20and%20hand%20motor%20skills%20compared%20with%20children%20without%20older%20siblings%20%28both%20b%3D0.55%2C%20all%20p%3C0.029%29.%20Boys%20had%20poorer%20scores%20than%20girls%20in%20body%20and%20hand%20motor%20skills%20and%20tracing%20%28b%3D%5Cu22120.45%2C%20%5Cu22120.68%20and%20%5Cu22121.5%2C%20all%20p%3C0.019%29.%20Children%20with%20behavioural%20difficulties%20had%20significantly%20poorer%20outcomes%20in%20most%20developmental%20domains.%20Some%20of%20the%20associations%20with%20SES%20and%20sex%20were%20stronger%20in%20older%20than%20in%20younger%20children.%20Associations%20between%20gestational%20age%20and%20motor%20development%20were%20weaker%20in%20older%20children.%20We%20did%20not%20find%20significant%20associations%20between%20child%20development%20and%20sleep%20duration%2C%20breastfeeding%20duration%20or%20overweight%5C%2Fobesity.%5CnConclusion%20Some%20factors%20had%20a%20protective%2C%20others%20an%20adverse%20effect%20on%20development%20of%20children%20under%206%20years%20of%20age.%20The%20effect%20of%20SES%20and%20sex%20increased%2C%20while%20the%20effect%20of%20gestational%20age%20decreased%20with%20age.%5CnTrial%20registration%20number%20NCT02550236.%22%2C%22date%22%3A%222022%5C%2F11%5C%2F01%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1136%5C%2Fbmjopen-2022-065936%22%2C%22ISSN%22%3A%222044-6055%2C%202044-6055%22%2C%22url%22%3A%22http%3A%5C%2F%5C%2Fbmjopen.bmj.com%5C%2Fcontent%5C%2F12%5C%2F11%5C%2Fe065936%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-07T07%3A01%3A28Z%22%7D%7D%2C%7B%22key%22%3A%226SC3V55H%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Brunnert%20et%20al.%22%2C%22parsedDate%22%3A%222022-09-27%22%2C%22numChildren%22%3A2%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EBrunnert%2C%20Lina%2C%20Ika%20Damayanti%20Puasa%2C%20Antje%20Garten%2C%20Melanie%20Penke%2C%20Susanne%20Gaul%2C%20Nico%20Grafe%2C%20Thomas%20Karlas%2C%20Wieland%20Kiess%2C%20Gunter%20Flemming%2C%20and%20Mandy%20Vogel.%20%26%23x201C%3BPediatric%20Percentiles%20for%20Transient%20Elastography%20Measurements%20-%20Effects%20of%20Age%2C%20Sex%2C%20Weight%20Status%20and%20Pubertal%20Stage.%26%23x201D%3B%20%3Ci%3EFrontiers%20in%20Endocrinology%3C%5C%2Fi%3E%2013%20%28September%2027%2C%202022%29%3A%201030809.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3389%5C%2Ffendo.2022.1030809%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3389%5C%2Ffendo.2022.1030809%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Pediatric%20percentiles%20for%20transient%20elastography%20measurements%20-%20effects%20of%20age%2C%20sex%2C%20weight%20status%20and%20pubertal%20stage%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Lina%22%2C%22lastName%22%3A%22Brunnert%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ika%20Damayanti%22%2C%22lastName%22%3A%22Puasa%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22Garten%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Melanie%22%2C%22lastName%22%3A%22Penke%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Susanne%22%2C%22lastName%22%3A%22Gaul%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Nico%22%2C%22lastName%22%3A%22Grafe%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Thomas%22%2C%22lastName%22%3A%22Karlas%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Gunter%22%2C%22lastName%22%3A%22Flemming%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%5D%2C%22abstractNote%22%3A%22Background%20and%20aims%5CnTransient%20Elastography%20is%20a%20non-invasive%2C%20cost-efficient%2C%20non-ionizing%2C%20observer-independent%20and%20reliable%20method%20to%20detect%20liver%20fibrosis%20using%20Liver%20Stiffness%20Measurement%20%28LSM%29%20and%20the%20degree%20of%20fat%20accumulation%20in%20the%20liver%20using%20Controlled%20Attenuation%20Parameter%20%28CAP%29.%20This%20study%20aims%20to%20derive%20reference%20values%20for%20both%20measures%20from%20healthy%20children%20and%20adolescents.%20Further%2C%20we%20aim%20to%20assess%20the%20potential%20influence%20of%20age%2C%20sex%2C%20puberty%2C%20and%20BMI-SDS%20on%20CAP%20and%20LSM.%5Cn%5CnMethods%5CnWithin%20the%20LIFE%20Child%20study%2C%20amongst%20others%2C%20anthropometric%20data%20and%20pubertal%20status%20were%20assessed.%20Transient%20Elastography%20%28TE%29%20was%20performed%20using%20the%20FibroScan%5Cu00ae%20device%20in%20a%20population-based%20cohort%20at%20982%20study%20visits%20of%20482%20healthy%20children%20aged%20between%2010%20and%2018%20years.%20Percentiles%20for%20LSM%20and%20CAP%20were%20estimated%2C%20and%20the%20effects%20of%20age%2C%20sex%2C%20puberty%20and%20weight%20status%20were%20assessed%20through%20hierarchical%20regression%20models.%5Cn%5CnResults%5CnThere%20was%20a%20strong%20age%20dependency%20for%20LSM%20with%20higher%20values%20for%20older%20children%2C%20most%20pronounced%20in%20the%20upper%20percentiles%20in%20boys.%20Contrarily%2C%20CAP%20was%20relatively%20stable%20across%20the%20age%20span%20without%20considerable%20difference%20between%20boys%20and%20girls.%20We%20found%20a%20significant%20positive%20correlation%20between%20BMI-SDS%20and%20both%20CAP%20and%20LSM%20for%20BMI-SDS%20%3E1.28.%20For%20BMI-SDS%20%3C%201.28%2C%20the%20association%20was%20also%20positive%20but%20reached%20statistical%20significance%20only%20for%20CAP.%20Further%2C%20the%20association%20between%20BMI-SDS%20and%20CAP%20was%20significantly%20stronger%20in%20younger%20than%20in%20older%20children.%20There%20was%20no%20association%20between%20pubertal%20status%20and%20CAP.%20For%20LSM%2C%20we%20found%20that%20children%20with%20a%20high%20BMI-SDS%20but%20not%20children%20with%20normal%20weight%20had%20significantly%20higher%20LSM%20values%20in%20Tanner%20stage%204.%5Cn%5CnConclusions%5CnAge%2C%20sex%2C%20pubertal%20status%20and%20weight%20status%20should%20be%20considered%20when%20interpreting%20LSM%20and%20CAP%20in%20pediatric%20patients%20to%20facilitate%20and%20improve%20early%20detection%20of%20abnormal%20liver%20function%2C%20which%20is%20associated%20with%20common%20pathologies%2C%20such%20as%20NAFLD.%22%2C%22date%22%3A%222022-9-27%22%2C%22language%22%3A%22%22%2C%22DOI%22%3A%2210.3389%5C%2Ffendo.2022.1030809%22%2C%22ISSN%22%3A%221664-2392%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.ncbi.nlm.nih.gov%5C%2Fpmc%5C%2Farticles%5C%2FPMC9551398%5C%2F%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-12-31T12%3A03%3A53Z%22%7D%7D%2C%7B%22key%22%3A%22EV7HF6VS%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Buchhardt%20et%20al.%22%2C%22parsedDate%22%3A%222022-06-22%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EBuchhardt%2C%20Jeanette%2C%20Wieland%20Kiess%2C%20Antje%20K%26%23xF6%3Brner%2C%20Ronald%20Biemann%2C%20Christian%20Hirsch%2C%20and%20Life%20Child%20Study%20Team.%20%26%23x201C%3BThe%20Influence%20of%20Steroid%20Hormones%20on%20Tooth%20Wear%20in%20Children%20and%20in%20Adolescents.%26%23x201D%3B%20%3Ci%3EJournal%20of%20Clinical%20Medicine%3C%5C%2Fi%3E%2011%2C%20no.%2013%20%28June%2022%2C%202022%29%3A%203603.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Fjcm11133603%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Fjcm11133603%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22The%20Influence%20of%20Steroid%20Hormones%20on%20Tooth%20Wear%20in%20Children%20and%20in%20Adolescents%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jeanette%22%2C%22lastName%22%3A%22Buchhardt%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ronald%22%2C%22lastName%22%3A%22Biemann%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christian%22%2C%22lastName%22%3A%22Hirsch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Life%22%2C%22lastName%22%3A%22Child%20Study%20Team%22%7D%5D%2C%22abstractNote%22%3A%22%281%29%20Background%3A%20From%20a%20young%20age%2C%20boys%20are%20more%20often%20affected%20by%20tooth%20wear%20than%20girls.%20This%20suggests%20an%20influence%20of%20the%20male%20sex%20hormone%20%28testosterone%29%20on%20the%20aetiology%20of%20tooth%20wear.%20The%20aim%20of%20the%20present%20study%20was%20to%20investigate%20the%20incidence%20of%20tooth%20wear%20in%20relation%20to%20steroid%20hormone%20levels%20in%20children.%20%282%29%20Methods%3A%201022%20test%20persons%20aged%20between%2010%20and%2018%20%28491%20male%2C%20531%20female%29%20from%20the%20LIFE%20Child%20study%20underwent%20medical%20and%20dental%20examination.%20Tooth%20wear%20was%20measured%20through%20clinical%20inspection.%20Blood%20samples%20were%20taken%20to%20determine%20hormone%20levels%20%28testosterone%2C%20SHBG%29.%20The%20level%20of%20free%20testosterone%20was%20calculated%20from%20the%20ratio%20of%20testosterone%20to%20SHBG.%20Using%20multivariable%20methods%2C%20the%20incidence%20of%20tooth%20wear%20was%20analyzed%20as%20a%20function%20of%20hormone%20levels%2C%20while%20controlling%20for%20confounders%20such%20as%20age%2C%20sex%2C%20social%20status%2C%20and%20orthodontic%20treatment.%20%283%29%20Results%3A%20The%20incidence%20of%20tooth%20wear%20increased%20with%20age%20in%20both%20sexes.%20Boys%20showed%20significantly%20more%20often%20attrition%20facets%20than%20girls%20%2817.5%25%20vs.%2013.2%25%2C%20p%20%26lt%3B%200.001%29.%20Subjects%20with%20tooth%20wear%20showed%20significantly%20higher%20free%20testosterone%20levels%20than%20those%20without%20%28males%3A%20p%20%26lt%3B%200.001%2C%20females%3A%20p%20%26lt%3B%200.05%29.%20After%20controlling%20for%20confounding%20variables%2C%20the%20risk%20of%20tooth%20wear%20increased%20by%20approximately%2030.0%25%20with%20each%20year%20of%20life%20%28odds%20ratio%20%5BOR%5Dboys%20%3D%201.29%2C%2095%25%20confidence%20interval%20%5BCI%5D%20%3D%201.04-1.56%3B%20%5BOR%5Dgirls%20%3D%201.32%2C%2095%25%20CI%20%3D%201.08-1.61%29.%20In%20addition%2C%20the%20risk%20of%20tooth%20wear%20increased%20by%206.0%25%20per%20free%20testosterone%20scale%20score%20only%20in%20boys%20%28OR%20%3D%201.06%2C%2095%25%20CI%20%3D%201.01-1.12%29.%20%284%29%20Conclusions%3A%20Tooth%20wear%20is%20common%20in%20children%20and%20in%20adolescents%2C%20and%20it%20increases%20steadily%20with%20age%20in%20both%20sexes.%20The%20stronger%20increase%20and%20the%20higher%20prevalence%20among%20male%20adolescents%20can%20be%20explained%20by%20the%20additional%20effect%20of%20free%20testosterone.%22%2C%22date%22%3A%222022-06-22%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.3390%5C%2Fjcm11133603%22%2C%22ISSN%22%3A%222077-0383%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-23T10%3A52%3A50Z%22%7D%7D%5D%7D
Holvoet, Sébastien, Francis Foata, Sophie Nutten, Ellen Ní Cléirigh, Maya Shevlyakova, Cheong Kwong Chung, Gregory Lefevre, et al. “Impact of Consumption of the Human Milk Oligosaccharides 2′-FL and LNnT on Reduction of Risk of Allergic Sensitisation.” Food and Agricultural Immunology 35, no. 1 (December 31, 2024): 2301703. https://doi.org/10.1080/09540105.2023.2301703.
Jensch, Ricky, Ronny Baber, Antje Körner, Wieland Kiess, Uta Ceglarek, Antje Garten, and Mandy Vogel. “Association of Whole Blood Amino Acid and Acylcarnitine Metabolome with Anthropometry and IGF-I Serum Levels in Healthy Children and Adolescents in Germany.” Metabolites 14, no. 9 (September 2024): 489. https://doi.org/10.3390/metabo14090489.
Wagner, Friederike, Robert Zeidler, Uta Ceglarek, Wieland Kiess, Jürgen Kratzsch, Alexander Gaudl, Ronald Biemann, and Mandy Vogel. “Obesity Is Associated with Increased 11-Oxyandrogen Serum Concentrations during Puberty.” Hormone Research in Paediatrics, July 22, 2024. https://doi.org/10.1159/000540433.
Grosse-Thie, Charlotte, Mandy Vogel, Ronny Baber, Uta Ceglarek, and Wieland Kiess. “Bilirubin Levels in Infancy and Their Associations with Body Weight, Levels of Iron-Related Parameters and Steroid Hormone Levels.” Metabolites 14, no. 7 (July 19, 2024): 393. https://doi.org/10.3390/metabo14070393.
Poulain, Tanja, Cornelia Hilbert, Annelie Grundmann, and Wieland Kiess. “Associations between Media Use at Bedtime and Sleep: A Cross-Sectional Analysis on Differences between Girls and Boys.” Frontiers in Psychology 15 (July 12, 2024). https://doi.org/10.3389/fpsyg.2024.1290935.
Prenzel, Freerk, Thorsten Kaiser, Anja Willenberg, Maike vom Hove, Gunter Flemming, Lars Fischer, Jürgen Kratzsch, Wieland Kiess, and Mandy Vogel. “Reference Intervals and Percentiles for Soluble Transferrin Receptor and STfR/Log Ferritin Index in Healthy Children and Adolescents.” Clinical Chemistry and Laboratory Medicine (CCLM), July 8, 2024. https://doi.org/10.1515/cclm-2024-0369.
Ober, Peggy, Tanja Poulain, Christof Meigen, Ulrike Spielau, Carolin Sobek, Wieland Kiess, Ulrike Igel, Tobias Lipek, and Mandy Vogel. “Modifiable Factors Influencing Attention Performance in Healthy Children: Insights from a Comprehensive School Nutrition Study.” BMC Public Health 24, no. 1 (June 19, 2024): 1629. https://doi.org/10.1186/s12889-024-19059-8.
Fechner, Anna, Anja Willenberg, Niels Ziegelasch, Andreas Merkenschlager, Wieland Kiess, and Mandy Vogel. “Creatine Kinase Serum Levels in Children Revisited: New Reference Intervals from a Large Cohort of Healthy Children and Adolescents.” Clinica Chimica Acta 560 (June 15, 2024): 119726. https://doi.org/10.1016/j.cca.2024.119726.
Tomar, A., M. Gomez-Velazquez, R. Gerlini, G. Comas-Armangué, L. Makharadze, T. Kolbe, A. Boersma, et al. “Epigenetic Inheritance of Diet-Induced and Sperm-Borne Mitochondrial RNAs.” Nature, June 5, 2024, 1–8. https://doi.org/10.1038/s41586-024-07472-3.
Ravi Teja, Kasagani Venkata, Bhanu Malhotra, Mandy Vogel, Raman Kumar Marwaha, Arun Aggarwal, Rimesh Pal, Liza Das, et al. “Normative Data for Insulin-like Growth Factor-1 (IGF-1) in Healthy Children and Adolescents from India.” The Journal of Clinical Endocrinology and Metabolism, May 15, 2024, dgae340. https://doi.org/2024061217375967200.
Barzen, Charlotte, Mandy Vogel, Wieland Kiess, and Tanja Poulain. “Associations between Gestational Weight Gain and Weight Development of the Offspring: Differences Depending on Maternal Pre-Pregnancy BMI.” Archives of Gynecology and Obstetrics, April 13, 2024. https://doi.org/10.1007/s00404-024-07487-1.
Stürzebecher, Paulina E., Konstantin L. Uttinger, Mandy Vogel, Maike Schlingmann, Uta Ceglarek, Berend Isermann, Wieland Kiess, Antje Körner, and Ulrich Laufs. “Lipoprotein(a) Serum Concentrations in Children in Relation to Body Mass Index, Age and Sex.” Pediatric Research, February 28, 2024. https://doi.org/10.1038/s41390-024-03108-4.
Scholz, Markus, Katrin Horn, Janne Pott, Matthias Wuttke, Andreas Kühnapfel, M. Kamal Nasr, Holger Kirsten, et al. “X-Chromosome and Kidney Function: Evidence from a Multi-Trait Genetic Analysis of 908,697 Individuals Reveals Sex-Specific and Sex-Differential Findings in Genes Regulated by Androgen Response Elements.” Nature Communications 15, no. 1 (January 18, 2024): 586. https://doi.org/10.1038/s41467-024-44709-1.
Fulfs, Theresa, Tanja Poulain, Mandy Vogel, Kolja Nenoff, and Wieland Kiess. “Associations between Sleep Problems and Emotional/Behavioural Difficulties in Healthy Children and Adolescents.” BMC Pediatrics 24, no. 1 (January 5, 2024): 15. https://doi.org/10.1186/s12887-023-04487-z.
Wilpert, Nina-Maria, Roma Thamm, Michael Thamm, Jürgen Kratzsch, Dominik Seelow, Mandy Vogel, Heiko Krude, and Markus Schuelke. “Normal Values for the FT3/FT4 Ratio: Centile Charts (0–29 Years) and Their Application for the Differential Diagnosis of Children with Developmental Delay.” International Journal of Molecular Sciences 25, no. 16 (January 2024): 8585. https://doi.org/10.3390/ijms25168585.
Ridefelt, Peter, Johan Saldeen, Mandy Vogel, Uta Ceglarek, Wieland Kiess, and Anders Larsson. “Pediatric Reference Intervals for Serum Folate and Cobalamin Based on a European Population without Exposure to Folic Acid Fortification.” Scandinavian Journal of Clinical and Laboratory Investigation online ahead of print, no. 0 (2024): 1–5. https://doi.org/10.1080/00365513.2024.2330918.
Petri, Laura, Tanja Poulain, Mandy Vogel, Christof Meigen, Wieland Kiess, and Andreas Hiemisch. “Parent-Perceived Recurrent Pain in Children: Associations with Maternal Pain, Depressiveness, Socioeconomic Status, and Children’s Behavioural Difficulties.” Frontiers in Pediatrics 12 (2024): 1287343. https://doi.org/10.3389/fped.2024.1287343.
Grüning Parache, Laura, Mandy Vogel, Christof Meigen, Wieland Kiess, and Tanja Poulain. “Family Structure, Socioeconomic Status, and Mental Health in Childhood.” European Child & Adolescent Psychiatry, December 26, 2023. https://doi.org/10.1007/s00787-023-02329-y.
Harings, Tanjana, Martina Patrizia Neininger, Simone Eisenhofer, Alena Gerlinde Thiele, Wieland Kiess, Astrid Bertsche, Skadi Beblo, and Thilo Bertsche. “Parents’ Perceptions Regarding Their Children’s Medications and Expert-Assessed Drug-Related Problems in Pediatric Patients with Inborn Errors of Metabolism.” Children (Basel, Switzerland) 10, no. 12 (November 29, 2023): 1873. https://doi.org/10.3390/children10121873.
Krause, Lea, Tanja Poulain, Wieland Kiess, and Mandy Vogel. “Body Image and Behavioural and Emotional Difficulties in German Children and Adolescents.” BMC Pediatrics 23, no. 1 (November 23, 2023): 594. https://doi.org/10.1186/s12887-023-04405-3.
Bier, Elisabeth, Mandy Vogel, Nico Grafe, Anne Jurkutat, Juliane Ludwig, Oleg Wagner, Christof Meigen, Wieland Kiess, and Tanja Poulain. “Children’s Satisfaction with a Comprehensive Study Program-Results from the LIFE Child Cohort Study.” Paediatric and Perinatal Epidemiology 37, no. 8 (November 2023): 704–9. https://doi.org/10.1111/ppe.13007.
Kiess, Alexandra, Jessica Green, Anja Willenberg, Uta Ceglarek, Ingo Dähnert, Wieland Kiess, and Mandy Vogel. “Influence of Growth and Metabolic Markers on Hs-Troponin T and NT-ProBNP Levels in Healthy Children.” Endocrine Connections 12, no. 10 (October 1, 2023). https://doi.org/10.1530/EC-23-0120.
Stein, Robert, Eric Göpel, Daniel Weghuber, Maximiliane Chiara Hammel, Mandy Vogel, Wieland Kiess, and Antje Körner. “Are There Relevant Thresholds of Insulin-Independent Indices across the Lifespan to Predict Alterations in Glycemic Control?—Authors’ Reply.” The Lancet Regional Health – Europe 33 (October 1, 2023): 100734. https://doi.org/10.1016/j.lanepe.2023.100734.
Roth, Christian, Franz Wolfgang Hirsch, Ina Sorge, Wieland Kiess, Anne Jurkutat, Maren Witt, Eva Böker, and Daniel Gräfe. “Preclinical Cartilage Changes of the Knee Joint in Adolescent Competitive Volleyball Players: A Prospective T2 Mapping Study.” RoFo: Fortschritte Auf Dem Gebiete Der Rontgenstrahlen Und Der Nuklearmedizin 195, no. 10 (October 2023): 913–23. https://doi.org/10.1055/a-2081-3245.
Dathan-Stumpf, Anne, Massimiliano Lia, Christof Meigen, Karoline Bornmann, Mireille Martin, Manuela Aßmann, Wieland Kiess, and Holger Stepan. “Novel Three-Dimensional Body Scan Anthropometry versus MR-Pelvimetry for Vaginal Breech Delivery Assessment.” Journal of Clinical Medicine 12, no. 19 (September 25, 2023): 6181. https://doi.org/10.3390/jcm12196181.
Kappelt, Jonas, Christof Meigen, Clara Elise Schild, Wieland Kiess, and Tanja Poulain. “Early Child Development and Its Determinants: Findings from a Large Cohort of Healthy Children Growing up in a Low-Risk Environment.” Child: Care, Health and Development n/a, no. n/a (September 22, 2023). https://doi.org/10.1111/cch.13177.
Nerius, Lena, Mandy Vogel, Uta Ceglarek, Wieland Kiess, Ronald Biemann, Holger Stepan, and Jürgen Kratzsch. “Bone Turnover in Lactating and Nonlactating Women.” Archives of Gynecology and Obstetrics, September 14, 2023. https://doi.org/10.1007/s00404-023-07189-0.
Strauch, Jacqueline-Michéle, Mandy Vogel, Christof Meigen, Uta Ceglarek, Jürgen Kratzsch, Anja Willenberg, and Wieland Kiess. “Pediatric Reference Values of Alkaline Phosphatase: Analysis from a German Population-Based Cohort and Influence of Anthropometric and Blood Parameters.” Bone 174 (September 1, 2023): 116809. https://doi.org/10.1016/j.bone.2023.116809.
Kabbani, Noura, Holger Stepan, Matthias Blüher, Thomas Ebert, Ronny Baber, Mandy Vogel, Wieland Kiess, et al. “Association between TGFβ1 Levels in Cord Blood and Weight Progress in the First Year of Life.” Biomedicines 11, no. 8 (August 8, 2023): 2220. https://doi.org/10.3390/biomedicines11082220.
Maidowski, Ludwig, Wieland Kiess, Ronny Baber, Anne Dathan-Stumpf, Uta Ceglarek, and Mandy Vogel. “Tracking of Serum Lipids in Healthy Children on a Year-to-Year Basis.” BMC Cardiovascular Disorders 23, no. 1 (August 2, 2023): 386. https://doi.org/10.1186/s12872-023-03391-9.
Stürzebecher, P., M. Schlingmann, K. Uttinger, M. Vogel, U. Ceglarek, B. Isermann, W. Kiess, A. Körner, and U. Laufs. “Lipoprotein(A) Serum Concentrations in Children Are Independent of Age, Sex, or Body Mass Index.” In Atherosclerosis, 379:S20. Elsevier, 2023. https://doi.org/10.1016/j.atherosclerosis.2023.06.739.
Sobek, Carolin, Peggy Ober, and Mandy Vogel. “Schulen im (Klima-)Wandel – Handlungsfelder.” Kinder- und Jugendmedizin 23, no. 4 (August 2023): 229–34. https://doi.org/10.1055/a-2104-3463.
Vogel, Mandy, Ruth Gausche, Tanja Poulain, and Wieland Kiess. “Wie Die Ungleiche Verteilung von Risiken Und Chancen Im Kindesalter Die Gesundheit Prägt – Ein Leben Lang (Und Darüber Hinaus),” 61–72, 2023.
Hammel, Maximiliane Chiara, Robert Stein, Jürgen Kratzsch, Mandy Vogel, Alexander J. Eckert, Rima Destya Triatin, Marco Colombo, et al. “Fasting Indices of Glucose-Insulin-Metabolism across Life Span and Prediction of Glycemic Deterioration in Children with Obesity from New Diagnostic Cut-Offs.” The Lancet Regional Health. Europe 30 (July 2023): 100652. https://doi.org/10.1016/j.lanepe.2023.100652.
Rauscher, Franziska G., Andreas Hiemisch, Wieland Kiess, and Ralf Blendowske. “Monochromatic Ocular High-Order Aberrations in Children and Adolescents.” Ophthalmic & Physiological Optics: The Journal of the British College of Ophthalmic Opticians (Optometrists) 43, no. 4 (July 2023): 842–59. https://doi.org/10.1111/opo.13151.
Wex, Isabel, Mandy Geserick, Tim Leibert, Ulrike Igel, Carolin Sobek, Christof Meigen, Wieland Kiess, and Mandy Vogel. “Active School Transport in an Urban Environment:Prevalence and Perceived Barriers.” BMC Public Health 23, no. 1 (March 23, 2023). https://doi.org/10.1186/s12889-023-15464-7.
Söhnel, Tanja, Christof Meigen, Andreas Hiemisch, Siegfried Wahl, Focke Ziemssen, Carolin Truckenbrod, Katharina Hübner, and Wieland Kiess. “Normative Data for Macular and Retinal Nerve Fibre Layer Thickness in Healthy German Children and Adolescents Using Optical Coherence Tomography.” Ophthalmic and Physiological Optics, March 17, 2023, opo.13123. https://doi.org/10.1111/opo.13123.
Dathan-Stumpf, Anne, Mandy Vogel, Nico Grafe, Wieland Kiess, and Holger Stepan. “Relation between Socioeconomic Status and Maternal Serum Lipids to Infant Lipid Concentrations and Anthropometry in the First Year of Life.” Archives of Gynecology and Obstetrics, March 2, 2023. https://doi.org/10.1007/s00404-023-06937-6.
Poulain, Tanja, Christof Meigen, Wieland Kiess, and Mandy Vogel. “Media Regulation Strategies in Parents of 4- to 16-Year-Old Children and Adolescents: A Cross-Sectional Study.” BMC Public Health 23, no. 1 (February 21, 2023): 371. https://doi.org/10.1186/s12889-023-15221-w.
Herzig, Markus, Astrid Bertsche, Cornelia Hilbert, Wieland Kiess, Thilo Bertsche, and Martina Patrizia Neininger. “Pharmacoepidemiological Analysis of Oral Contraceptive Use in Adolescents in a German Longitudinal Cohort Study.” Children (Basel, Switzerland) 10, no. 2 (February 16, 2023): 393. https://doi.org/10.3390/children10020393.
Förster, Lucas-Johann, Mandy Vogel, Robert Stein, Anja Hilbert, Julius Lars Breinker, Marleen Böttcher, Wieland Kiess, and Tanja Poulain. “Mental Health in Children and Adolescents with Overweight or Obesity.” BMC Public Health 23, no. 1 (January 19, 2023): 135. https://doi.org/10.1186/s12889-023-15032-z.
Roth, Anna, Christof Meigen, Andreas Hiemisch, Wieland Kiess, and Tanja Poulain. “Associations between Stressful Life Events and Increased Physical and Psychological Health Risks in Adolescents: A Longitudinal Study.” International Journal of Environmental Research and Public Health 20, no. 2 (January 6, 2023): 1050. https://doi.org/10.3390/ijerph20021050.
Stein, Robert, Florian Koutny, Johannes Riedel, Natascha Dörr, Klara Meyer, Marco Colombo, Mandy Vogel, et al. “Single Point Insulin Sensitivity Estimator (SPISE) as a Prognostic Marker for Emerging Dysglycemia in Children with Overweight or Obesity.” Metabolites 13, no. 1 (January 2023): 100. https://doi.org/10.3390/metabo13010100.
Hirsch, Christian, Oliver Schierz, Antje Körner, Wieland Kiess, Ronald Biemann, Annett Schrock, and Jens Christoph Türp. “Sex Hormones Associated with Temporomandibular Pain on Palpation in Male Adolescents—Results of the Epidemiologic LIFE Child Study.” Journal of Oral Rehabilitation n/a, no. n/a (2023). https://doi.org/10.1111/joor.13530.
Schmidt, Ricarda, Andreas Hiemisch, Wieland Kiess, Kai von Klitzing, Franziska Schlensog-Schuster, and Anja Hilbert. “Validation Study on the Child, Adult, and Parent Version of the ARFID Module 2.0 for the Eating Disorder Examination.” The International Journal of Eating Disorders 55, no. 12 (December 2022): 1708–20. https://doi.org/10.1002/eat.23805.
Pfäffle, Roland, Matthias Knüpfer, Melanie Göbert, Mandy Vogel, Ruth Gausche, Christoph Beger, Eberhard Keller, Antje Körner, Ulrich Thome, and Wieland Kiess. “Growth Patterns of Children With Short Stature in Adulthood According to Auxological Status and Maturity at Birth.” The Journal of Clinical Endocrinology and Metabolism 107, no. 12 (November 25, 2022): 3320–27. https://doi.org/2022112511292049000.
Philipp, Dariusch, Mandy Vogel, Manuela Brandt, Franziska G. Rauscher, Andreas Hiemisch, Siegfried Wahl, Wieland Kiess, and Tanja Poulain. “The Relationship between Myopia and near Work, Time Outdoors and Socioeconomic Status in Children and Adolescents.” BMC Public Health 22, no. 1 (November 10, 2022): 2058. https://doi.org/10.1186/s12889-022-14377-1.
Schild, Clara Elise, Christof Meigen, Jonas Kappelt, Wieland Kiess, and Tanja Poulain. “Associations between Sociodemographic and Behavioural Parameters and Child Development Depending on Age and Sex: A Cross-Sectional Analysis.” BMJ Open 12, no. 11 (November 1, 2022): e065936. https://doi.org/10.1136/bmjopen-2022-065936.
Brunnert, Lina, Ika Damayanti Puasa, Antje Garten, Melanie Penke, Susanne Gaul, Nico Grafe, Thomas Karlas, Wieland Kiess, Gunter Flemming, and Mandy Vogel. “Pediatric Percentiles for Transient Elastography Measurements – Effects of Age, Sex, Weight Status and Pubertal Stage.” Frontiers in Endocrinology 13 (September 27, 2022): 1030809. https://doi.org/10.3389/fendo.2022.1030809.
Buchhardt, Jeanette, Wieland Kiess, Antje Körner, Ronald Biemann, Christian Hirsch, and Life Child Study Team. “The Influence of Steroid Hormones on Tooth Wear in Children and in Adolescents.” Journal of Clinical Medicine 11, no. 13 (June 22, 2022): 3603. https://doi.org/10.3390/jcm11133603.
2390247
T52N9QLZ
covid19
1
chicago-fullnote-bibliography
50
date
desc
1
1
6748
https://home.uni-leipzig.de/lifechild/wp-content/plugins/zotpress/
%7B%22status%22%3A%22success%22%2C%22updateneeded%22%3Afalse%2C%22instance%22%3Afalse%2C%22meta%22%3A%7B%22request_last%22%3A0%2C%22request_next%22%3A0%2C%22used_cache%22%3Atrue%7D%2C%22data%22%3A%5B%7B%22key%22%3A%22VW9I9DSC%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Poulain%20et%20al.%22%2C%22parsedDate%22%3A%222022-06-02%22%2C%22numChildren%22%3A3%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EPoulain%2C%20Tanja%2C%20Christof%20Meigen%2C%20Wieland%20Kiess%2C%20and%20Mandy%20Vogel.%20%26%23x201C%3BAn%20Online%20Survey%20Carried%20Out%20in%202022%20Showed%20That%20Covid-19%20Was%20Associated%20with%20Negative%20Changes%20in%20Children%26%23×2019%3Bs%20Lives.%26%23x201D%3B%20%3Ci%3EActa%20Paediatrica%20%28Oslo%2C%20Norway%3A%201992%29%3C%5C%2Fi%3E%2C%20June%202%2C%202022.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fapa.16435%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fapa.16435%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22An%20Online%20Survey%20Carried%20Out%20in%202022%20Showed%20That%20Covid-19%20Was%20Associated%20with%20Negative%20Changes%20in%20Children%27s%20Lives%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christof%22%2C%22lastName%22%3A%22Meigen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%5D%2C%22abstractNote%22%3A%22%22%2C%22date%22%3A%222022-06-02%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1111%5C%2Fapa.16435%22%2C%22ISSN%22%3A%221651-2227%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-24T11%3A00%3A36Z%22%7D%7D%2C%7B%22key%22%3A%2247FY4H7A%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Kiess%20et%20al.%22%2C%22parsedDate%22%3A%222022-02%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EKiess%2C%20Wieland%2C%20Anna%20S.%20Kirstein%2C%20Robert%20Stein%2C%20and%20Mandy%20Vogel.%20%26%23x201C%3BObesity%20After%20the%20Covid-19%20Pandemic%20and%20Beyond.%26%23x201D%3B%20%3Ci%3EJournal%20of%20Pediatric%20Endocrinology%20and%20Metabolism%3C%5C%2Fi%3E%2035%2C%20no.%202%20%28February%202022%29%3A%20135%26%23×2013%3B38.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1515%5C%2Fjpem-2022-2135%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1515%5C%2Fjpem-2022-2135%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Obesity%20After%20the%20Covid-19%20Pandemic%20and%20Beyond%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anna%20S.%22%2C%22lastName%22%3A%22Kirstein%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Robert%22%2C%22lastName%22%3A%22Stein%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%5D%2C%22abstractNote%22%3A%22Article%20Obesity%20after%20the%20Covid-19%20pandemic%20and%20beyond%20was%20published%20on%20February%201%2C%202022%20in%20the%20journal%20Journal%20of%20Pediatric%20Endocrinology%20and%20Metabolism%20%28volume%2035%2C%20issue%202%29.%22%2C%22date%22%3A%222022-02%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1515%5C%2Fjpem-2022-2135%22%2C%22ISSN%22%3A%222191-0251%22%2C%22url%22%3A%22http%3A%5C%2F%5C%2Fwww.degruyter.com%5C%2Fdocument%5C%2Fdoi%5C%2F10.1515%5C%2Fjpem-2022-2135%5C%2Fhtml%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-24T09%3A07%3A23Z%22%7D%7D%2C%7B%22key%22%3A%226XRRMRCU%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Brandstetter%20et%20al.%22%2C%22parsedDate%22%3A%222022-01%22%2C%22numChildren%22%3A2%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EBrandstetter%2C%20Susanne%2C%20Tanja%20Poulain%2C%20Mandy%20Vogel%2C%20Christof%20Meigen%2C%20Michael%20Melter%2C%20Angela%20K%26%23xF6%3Bninger%2C%20Christian%20Apfelbacher%2C%20et%20al.%20%26%23x201C%3BFamilies%26%23×2019%3B%20Worries%20During%20the%20First%20and%20Second%20Covid-19%20Wave%20in%20Germany%3A%20Longitudinal%20Study%20in%20Two%20Population-Based%20Cohorts.%26%23x201D%3B%20%3Ci%3EInternational%20Journal%20of%20Environmental%20Research%20and%20Public%20Health%3C%5C%2Fi%3E%2019%2C%20no.%205%20%28January%202022%29%3A%202820.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Fijerph19052820%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Fijerph19052820%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Families%5Cu2019%20Worries%20During%20the%20First%20and%20Second%20Covid-19%20Wave%20in%20Germany%3A%20Longitudinal%20Study%20in%20Two%20Population-Based%20Cohorts%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Susanne%22%2C%22lastName%22%3A%22Brandstetter%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christof%22%2C%22lastName%22%3A%22Meigen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Michael%22%2C%22lastName%22%3A%22Melter%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Angela%22%2C%22lastName%22%3A%22K%5Cu00f6ninger%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christian%22%2C%22lastName%22%3A%22Apfelbacher%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Michael%22%2C%22lastName%22%3A%22Kabesch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22%22%2C%22lastName%22%3A%22KUNO%20Kids%20Study%20Group%22%7D%5D%2C%22abstractNote%22%3A%22This%20study%20aimed%20to%20compare%20worries%20related%20to%20the%20Coronavirus%20disease%202019%20%28COVID-19%29%20in%20families%20with%20young%20children%20in%20two%20regions%20in%20Germany%20differently%20affected%20by%20the%20pandemic%20%28Regensburg%20in%20Southeast%20Germany%2C%20Leipzig%20in%20Eastern%20Germany%29%20during%20the%20first%20and%20the%20second%20waves%20of%20the%20COVID-19%20pandemic.%20720%20parents%20participating%20in%20the%20KUNO%20Kids%20health%20study%20in%20Regensburg%20%28n%20%3D%20507%29%20or%20the%20LIFE%20Child%20study%20in%20Leipzig%20%28n%20%3D%20213%29%20answered%20questions%20regarding%20COVID-19-related%20worries%20and%20trust%20in%20anti-pandemic%20policy%20measures%20during%20the%20first%20wave%20%28spring%202020%29%20and%20during%20the%20second%20wave%20%28winter%202020%5C%2F2021%29%20of%20the%20pandemic.%20Ordinal%20mixed-effects%20models%20were%20performed%20to%20assess%20differences%20depending%20on%20region%20and%20time%2C%20adjusting%20for%20education%20and%20migration%20background.%20Participants%20worried%20most%20about%20the%20general%20economic%20situation%20and%20their%20family%20and%20least%20about%20their%20own%20health%20or%20financial%20situation.%20Worries%20about%20oneself%2C%20family%2C%20friends%2C%20hometown%2C%20and%20country%20were%20stronger%20during%20the%20second%20than%20during%20the%20first%20wave.%20In%20regional%20comparisons%2C%20worries%20about%20family%2C%20friends%2C%20and%20hometown%20increased%20more%20pronouncedly%20from%20wave%201%20to%20wave%202%20in%20Leipzig%20%28OR%20ranging%20from%202.67%20%2895%25%20CI%201.71%5Cu20134.19%29%20to%203.01%20%2895%25%20CI%201.93%5Cu20134.71%29%2C%20all%20p%20%3C%200.001%29%20than%20in%20Regensburg%20%28OR%20ranging%20from%20to%201.38%20%2895%25%20CI%201.08%5Cu20131.78%29%20to%201.72%20%2895%25%20CI%201.33%5Cu20132.21%29%2C%20all%20p%20%3C%200.05%29%2C%20running%20parallel%20with%20the%20increase%20in%20SARS-CoV-2%20infections.%20Trust%20in%20anti-pandemic%20policy%20measures%2C%20in%20contrast%2C%20decreased%20significantly%20between%20wave%201%20and%20wave%202%2C%20with%20a%20stronger%20decrease%20in%20Regensburg%20%28OR%20%3D%200.30%20%2895%25%20CI%200.22%5Cu20130.39%29%2C%20p%20%3C%200.001%29%20than%20in%20Leipzig%20%28OR%20%3D%200.91%20%2895%25%20CI%200.59%5Cu20131.41%29%2C%20n.s.%29.%20The%20degree%20of%20families%5Cu2019%20COVID-19-related%20worries%20differs%20by%20region%20and%20time%2C%20which%20might%20be%20related%20to%20differences%20in%20infection%20rates%20and%20public%20interest.%20Regional%20differences%20should%20be%20taken%20into%20account%20when%20developing%20communication%20strategies%20and%20policy%20measures%20during%20the%20COVID-19%20pandemic.%22%2C%22date%22%3A%222022%5C%2F1%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.3390%5C%2Fijerph19052820%22%2C%22ISSN%22%3A%221660-4601%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.mdpi.com%5C%2F1660-4601%5C%2F19%5C%2F5%5C%2F2820%22%2C%22collections%22%3A%5B%22GQV6TIX2%22%2C%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-07T07%3A01%3A54Z%22%7D%7D%2C%7B%22key%22%3A%22MDV47R35%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Jurkutat%20et%20al.%22%2C%22parsedDate%22%3A%222022-01%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EJurkutat%2C%20Anne%2C%20Christof%20Meigen%2C%20Melanie%20Maier%2C%20Nico%20Grafe%2C%20Uwe%20G.%20Liebert%2C%20and%20Wieland%20Kiess.%20%26%23x201C%3BScreening%20for%20Sars-Cov-2%20in%20Non-Symptomatic%20Students%20and%20Staff%20Shows%20Safe%20School%20Openings%20Under%20Varying%20Incidence%20with%20Sufficient%20Mandatory%20Measures.%26%23x201D%3B%20%3Ci%3EActa%20Paediatrica%20%28Oslo%2C%20Norway%3A%201992%29%3C%5C%2Fi%3E%20online%20ahead%20of%20print%20%28January%202022%29.%20https%3A%5C%2F%5C%2Fdoi.org%5C%2F%3Ca%20class%3D%27zp-ItemURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fapa.16245%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fapa.16245%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Screening%20for%20Sars-Cov-2%20in%20Non-Symptomatic%20Students%20and%20Staff%20Shows%20Safe%20School%20Openings%20Under%20Varying%20Incidence%20with%20Sufficient%20Mandatory%20Measures%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anne%22%2C%22lastName%22%3A%22Jurkutat%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christof%22%2C%22lastName%22%3A%22Meigen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Melanie%22%2C%22lastName%22%3A%22Maier%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Nico%22%2C%22lastName%22%3A%22Grafe%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Uwe%20G.%22%2C%22lastName%22%3A%22Liebert%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%5D%2C%22abstractNote%22%3A%22%22%2C%22date%22%3A%222022-01%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%22https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fapa.16245%22%2C%22ISSN%22%3A%221651-2227%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fapa.16245%22%2C%22collections%22%3A%5B%22GQV6TIX2%22%2C%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222024-03-22T11%3A58%3A08Z%22%7D%7D%2C%7B%22key%22%3A%22BKYSLV9N%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Vogel%20et%20al.%22%2C%22parsedDate%22%3A%222022-01%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EVogel%2C%20Mandy%2C%20Mandy%20Geserick%2C%20Ruth%20Gausche%2C%20Christoph%20Beger%2C%20Tanja%20Poulain%2C%20Christof%20Meigen%2C%20Antje%20K%26%23xF6%3Brner%2C%20Eberhard%20Keller%2C%20Wieland%20Kiess%2C%20and%20Roland%20Pf%26%23xE4%3Bffle.%20%26%23x201C%3BAge-%20and%20Weight%20Group-Specific%20Weight%20Gain%20Patterns%20in%20Children%20and%20Adolescents%20During%20the%2015%20Years%20Before%20and%20During%20the%20Covid-19%20Pandemic.%26%23x201D%3B%20%3Ci%3EInternational%20Journal%20of%20Obesity%20%282005%29%3C%5C%2Fi%3E%2046%2C%20no.%201%20%28January%202022%29%3A%20144%26%23×2013%3B52.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1038%5C%2Fs41366-021-00968-2%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1038%5C%2Fs41366-021-00968-2%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Age-%20and%20Weight%20Group-Specific%20Weight%20Gain%20Patterns%20in%20Children%20and%20Adolescents%20During%20the%2015%20Years%20Before%20and%20During%20the%20Covid-19%20Pandemic%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Geserick%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ruth%22%2C%22lastName%22%3A%22Gausche%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christoph%22%2C%22lastName%22%3A%22Beger%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christof%22%2C%22lastName%22%3A%22Meigen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Eberhard%22%2C%22lastName%22%3A%22Keller%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Roland%22%2C%22lastName%22%3A%22Pf%5Cu00e4ffle%22%7D%5D%2C%22abstractNote%22%3A%22BACKGROUND%5C%2FOBJECTIVES%3A%20There%20is%20a%20concern%20that%20measures%20aiming%20to%20limit%20a%20further%20spread%20of%20COVID-19%2C%20e.g.%2C%20school%20closures%20and%20social%20distancing%2C%20cause%20an%20aggravation%20of%20the%20childhood%20obesity%20epidemic.%20Therefore%2C%20we%20compared%20BMI%20trends%20during%20the%2015%20years%20before%20and%20during%20the%20COVID-19%20pandemic.%5CnSUBJECTS%5C%2FMETHODS%3A%20To%20assess%20the%20change%20in%20weight%20dynamics%20during%20the%20first%20months%20of%20COVID-19%2C%20we%20compared%20the%20trends%20of%203-month%20change%20in%20BMI-SDS%20%28%5Cu0394BMI-SDS%29%20and%20the%20proportions%20of%20children%20showing%20a%20high%20positive%20%28HPC%29%20or%20high%20negative%20%28HNC%29%20weight%20change%20between%202005%20and%202019%20and%20the%20respective%20changes%20from%202019%20%28pre-pandemic%29%20to%202020%20%28after%20the%20onset%20of%20anti-pandemic%20measures%29%20in%20more%20than%20150%2C000%20children%20%289689%20during%20the%20pandemic%20period%29.%20The%20period%20of%203%20months%20corresponds%20approximately%20to%20the%20first%20lockdown%20period%20in%20Germany.%5CnRESULTS%3A%20During%20the%20COVID-19%20pandemic%2C%20we%20found%20a%20substantial%20weight%20gain%20across%20all%20weight%20and%20age%20groups%2C%20reflected%20by%20an%20increase%20in%20the%203-month%20change%20in%20BMI-SDS%20%28%5Cu03b2%5Cu2009%3D%5Cu20090.05%2C%20p%5Cu2009%3C%5Cu20090.001%29%2C%20an%20increase%20in%20the%20proportion%20of%20children%20showing%20HPC%20%28OR%5Cu2009%3D%5Cu20091.4%2C%20p%5Cu2009%3C%5Cu20090.001%29%2C%20and%20a%20decrease%20in%20the%20proportion%20of%20children%20showing%20HNC%20%28OR%5Cu2009%3D%5Cu20090.7%2C%20p%5Cu2009%3C%5Cu20090.001%29.%20Besides%2C%20we%20found%20the%20same%20trends%20since%202005%20on%20a%20low%20but%20stable%20level%20with%20a%20yearly%20increase%20of%20%5Cu0394BMI-SDS%20by%20%5Cu03b2%5Cu2009%3D%5Cu20090.001%20%28p%5Cu2009%3C%5Cu20090.001%29%2C%20the%20odds%20of%20HPC%20increased%20by%20ORhigh_pos%5Cu2009%3D%5Cu20091.01%20%28p%5Cu2009%3C%5Cu20090.001%29%2C%20and%20the%20odds%20of%20HNC%20decreased%20by%20ORhigh_neg%5Cu2009%3D%5Cu20090.99%20%28p%5Cu2009%3C%5Cu20090.001%29.%20These%20rather%20small%20effects%20accumulated%20to%20%5Cu03b2%5Cu2009%3D%5Cu20090.02%2C%20ORhigh_pos%5Cu2009%3D%5Cu20091.14%2C%20and%20ORhigh_pos%5Cu2009%3D%5Cu20090.85%20over%20the%20whole%20period%202005-2019.%20Alarmingly%2C%20both%20the%20long-term%20and%20the%20short-term%20effects%20were%20most%20pronounced%20in%20the%20obese%20subgroup.%5CnCONCLUSIONS%3A%20There%20are%20positive%20dynamics%20in%20different%20measures%20of%20weight%20change%2C%20indicating%20a%20positive%20trend%20in%20weight%20gain%20patterns%2C%20especially%20within%20the%20group%20of%20children%20with%20obesity.%20These%20dynamics%20are%20likely%20to%20be%20escalated%20by%20COVID-19-related%20measures.%20Thus%2C%20they%20may%20lead%20to%20a%20significant%20further%20aggravation%20of%20the%20childhood%20obesity%20pandemic.%22%2C%22date%22%3A%222022-01%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1038%5C%2Fs41366-021-00968-2%22%2C%22ISSN%22%3A%221476-5497%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-12-30T09%3A12%3A08Z%22%7D%7D%2C%7B%22key%22%3A%22ETFXTELD%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Vogel%20et%20al.%22%2C%22parsedDate%22%3A%222022%22%2C%22numChildren%22%3A2%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EVogel%2C%20Mandy%2C%20Mandy%20Geserick%2C%20Ruth%20Gausche%2C%20Christoph%20Beger%2C%20Tanja%20Poulain%2C%20Christof%20Meigen%2C%20Antje%20K%26%23xF6%3Brner%2C%20et%20al.%20%26%23x201C%3BGewichtszunahme%20Bei%20Kindern%20Und%20Jugendlichen%20W%26%23xE4%3Bhrend%20Der%20Covid-19-Pandemie.%26%23x201D%3B%20%3Ci%3EKinder-%20Und%20Jugendmedizin%3C%5C%2Fi%3E%2022%2C%20no.%202%20%282022%29%3A%20112%26%23×2013%3B17.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1055%5C%2Fa-1732-1623%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1055%5C%2Fa-1732-1623%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Gewichtszunahme%20bei%20Kindern%20und%20Jugendlichen%20w%5Cu00e4hrend%20der%20Covid-19-Pandemie%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Geserick%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ruth%22%2C%22lastName%22%3A%22Gausche%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christoph%22%2C%22lastName%22%3A%22Beger%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christof%22%2C%22lastName%22%3A%22Meigen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Carolin%22%2C%22lastName%22%3A%22Sobek%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Eberhard%22%2C%22lastName%22%3A%22Keller%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Roland%22%2C%22lastName%22%3A%22Pf%5Cu00e4ffle%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%5D%2C%22abstractNote%22%3A%22Es%20wurde%20viel%20dar%5Cu00fcber%20spekuliert%2C%20ob%20durch%20Schulschlie%5Cu00dfungen%2C%20eingeschr%5Cu00e4nkte%20soziale%20Kontakte%20und%20den%20Wegfall%20sportlicher%20Aktivit%5Cu00e4ten%20w%5Cu00e4hrend%20der%20Covid-19-Pandemie%20die%20Adipositasepidemie%20im%20Kindesalter%20verst%5Cu00e4rkt%20werden%20w%5Cu00fcrde.%20Deshalb%20haben%20wir%20die%20BMI-Verl%5Cu00e4ufe%20w%5Cu00e4hrend%20der%2015%20Jahre%20vor%20und%20w%5Cu00e4hrend%20der%20Covid-19-Pandemie%20untersucht.%20Der%20Trend%20der%20BMI-Ver%5Cu00e4nderungen%20%28als%20delta-BMI-SDS%29%20und%20die%20Anteile%20der%20Kinder%2C%20die%20Gewicht%20zunahmen%20bzw.%20verloren%2C%20zwischen%202005%20und%202019%20sowie%20entsprechend%20Daten%20von%202019%20vor%20der%20Pandemie%20und%20von%202020%20nach%20dem%20Einsetzen%20der%20ersten%20Pandemiema%5Cu00dfnahmen%20wurden%20bei%20mehr%20als%20150%20000%20Kindern%20%28ca.%2010%20000%20in%20der%20pandemischen%20Phase%29%20verglichen.%20W%5Cu00e4hrend%20der%20Covid-19-Pandemie%20fand%20sich%20eine%20substanzielle%20Gewichtszunahme%20%5Cu00fcber%20alle%20Gewichtsklassen%20und%20Altersstufen%20hinweg.%20Die%20%5Cu00c4nderung%20des%20mittleren%20BMI-SDS%20war%20wesentlich%20h%5Cu00f6her%20als%20in%20den%20Jahren%20zuvor.%20Ebenso%20stieg%20der%20Anteil%20der%20Kinder%2C%20die%20Gewicht%20zunahmen.%20Der%20Anteil%20der%20Kinder%2C%20die%20Gewicht%20%5Cu00fcber%20den%20Zeitraum%20verloren%2C%20nahm%20hingegen%20ab.%20Au%5Cu00dferdem%20fanden%20wir%20%5Cu00e4hnliche%20Trends%2C%20der%20zwar%20auf%20eine%20wesentlich%20schw%5Cu00e4chere%2C%20aber%20doch%20stetige%20Gewichtszunahme%20hinweisen%2C%20bereits%20seit%202005.%20Es%20ist%20alarmierend%2C%20dass%20sowohl%20der%20langfristige%20Trend%20als%20auch%20die%20kurzfristigen%2C%20pandemie-bezogenen%20Effekte%20bei%20Kindern%2C%20die%20bereits%20%5Cu00fcbergewichtig%20oder%20adip%5Cu00f6s%20waren%2C%20am%20gr%5Cu00f6%5Cu00dften%20waren.%5Cn%5CnDie%20Trends%2C%20die%20wir%20in%20mehreren%20Parametern%20der%20Gewichtsver%5Cu00e4nderung%20%5Cu00fcber%20einen%20Zeitraum%20von%20mehr%20als%2015%20Jahren%20beobachten%20konnten%2C%20weisen%20auf%20eine%20Zunahme%20des%20BMI-SDS.%20Besonders%20bei%20adip%5Cu00f6sen%20Kindern%20ist%20diese%20Dynamik%20ausgepr%5Cu00e4gt.%20Covid-19-bezogene%20Ma%5Cu00dfnahmen%20verst%5Cu00e4rken%20die%20Effekte%20und%20k%5Cu00f6nnten%20damit%20die%20Adipositasepidemie%20im%20Kindesalter%20weiter%20eskalieren.%22%2C%22date%22%3A%222022%22%2C%22language%22%3A%22%22%2C%22DOI%22%3A%2210.1055%5C%2Fa-1732-1623%22%2C%22ISSN%22%3A%22%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-24T13%3A35%3A12Z%22%7D%7D%2C%7B%22key%22%3A%22H5ZL4G3U%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Vogel%20et%20al.%22%2C%22parsedDate%22%3A%222021-04%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EVogel%2C%20Mandy%2C%20Christoph%20Beger%2C%20Ruth%20Gausche%2C%20Anne%20Jurkutat%2C%20Roland%20Pfaeffle%2C%20Antje%20K%26%23xF6%3Brner%2C%20Christof%20Meigen%2C%20Tanja%20Poulain%2C%20and%20Wieland%20Kiess.%20%26%23x201C%3BCovid-19%20Pandemic%20and%20Families%26%23×2019%3B%20Utilization%20of%20Well-Child%20Clinics%20and%20Pediatric%20Practices%20Attendance%20in%20Germany.%26%23x201D%3B%20%3Ci%3EBMC%20Research%20Notes%3C%5C%2Fi%3E%2014%2C%20no.%201%20%28April%202021%29%3A%20140.%20%3Ca%20class%3D%27zp-ItemURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs13104-021-05562-3%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs13104-021-05562-3%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Covid-19%20Pandemic%20and%20Families%27%20Utilization%20of%20Well-Child%20Clinics%20and%20Pediatric%20Practices%20Attendance%20in%20Germany%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christoph%22%2C%22lastName%22%3A%22Beger%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ruth%22%2C%22lastName%22%3A%22Gausche%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anne%22%2C%22lastName%22%3A%22Jurkutat%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Roland%22%2C%22lastName%22%3A%22Pfaeffle%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christof%22%2C%22lastName%22%3A%22Meigen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%5D%2C%22abstractNote%22%3A%22The%20COVID-19%20pandemic%20and%20the%20measures%20implemented%20to%20stop%20the%20pandemic%20had%20a%20broad%20impact%20on%20our%20daily%20lives.%20Besides%20work%20and%20social%20life%2C%20health%20care%20is%20affected%20on%20many%20levels.%20In%20particular%2C%20there%20is%20concern%20that%20attendance%20in%20health%20care%20programs%20will%20drop%20or%20hospital%20admissions%20will%20be%20delayed%20due%20to%20COVID-19-related%20anxieties%2C%20especially%20in%20children.%20Therefore%2C%20we%20compared%20the%20number%20of%20weekly%20visits%20to%2078%20German%20pediatric%20institutions%20between%202019%20and%202020.%22%2C%22date%22%3A%22April%2C%202021%22%2C%22language%22%3A%22%22%2C%22DOI%22%3A%2210.1186%5C%2Fs13104-021-05562-3%22%2C%22ISSN%22%3A%221756-0500%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs13104-021-05562-3%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-07T07%3A01%3A21Z%22%7D%7D%2C%7B%22key%22%3A%22B4NTM8V2%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Kiess%20et%20al.%22%2C%22parsedDate%22%3A%222021-04%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EKiess%2C%20Wieland%2C%20Tanja%20Poulain%2C%20Anne%20Jurkutat%2C%20Anna%20Kirstein%2C%20and%20Mandy%20Vogel.%20%26%23x201C%3BCovid19%20Pandemic%20and%20Pediatric%20Endocrinology%20and%20Metabolism-Are%20We%20Through%20with%20It%3F%26%23x201D%3B%20%3Ci%3EJournal%20of%20Pediatric%20Endocrinology%20%26amp%3B%20Metabolism%3A%20JPEM%3C%5C%2Fi%3E%2034%2C%20no.%205%20%28April%202021%29%3A%20535%26%23×2013%3B37.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1515%5C%2Fjpem-2021-2133%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1515%5C%2Fjpem-2021-2133%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Covid19%20Pandemic%20and%20Pediatric%20Endocrinology%20and%20Metabolism-Are%20We%20Through%20with%20It%3F%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anne%22%2C%22lastName%22%3A%22Jurkutat%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anna%22%2C%22lastName%22%3A%22Kirstein%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%5D%2C%22abstractNote%22%3A%22%22%2C%22date%22%3A%222021-04%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1515%5C%2Fjpem-2021-2133%22%2C%22ISSN%22%3A%222191-0251%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Forgid.org%5C%2F10.1515%5C%2Fjpem-2021-2133%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-07T07%3A01%3A41Z%22%7D%7D%2C%7B%22key%22%3A%226MPTPUJJ%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Poulain%20et%20al.%22%2C%22parsedDate%22%3A%222021-03%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EPoulain%2C%20Tanja%2C%20Christof%20Meigen%2C%20Carolin%20Sobek%2C%20Peggy%20Ober%2C%20Ulrike%20Igel%2C%20Antje%20K%26%23xF6%3Brner%2C%20Wieland%20Kiess%2C%20and%20Mandy%20Vogel.%20%26%23x201C%3BLoss%20of%20Childcare%20and%20Classroom%20Teaching%20During%20the%20Covid-19-Related%20Lockdown%20in%20Spring%202020%3A%20A%20Longitudinal%20Study%20on%20Consequences%20on%20Leisure%20Behavior%20and%20Schoolwork%20at%20Home.%26%23x201D%3B%20%3Ci%3EPloS%20One%3C%5C%2Fi%3E%2016%2C%20no.%203%20%28March%202021%29%3A%20e0247949.%20%3Ca%20class%3D%27zp-ItemURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1371%5C%2Fjournal.pone.0247949%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1371%5C%2Fjournal.pone.0247949%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Loss%20of%20Childcare%20and%20Classroom%20Teaching%20During%20the%20Covid-19-Related%20Lockdown%20in%20Spring%202020%3A%20A%20Longitudinal%20Study%20on%20Consequences%20on%20Leisure%20Behavior%20and%20Schoolwork%20at%20Home%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christof%22%2C%22lastName%22%3A%22Meigen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Carolin%22%2C%22lastName%22%3A%22Sobek%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Peggy%22%2C%22lastName%22%3A%22Ober%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ulrike%22%2C%22lastName%22%3A%22Igel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%5D%2C%22abstractNote%22%3A%22AIM%3A%20In%20spring%202020%2C%20the%20first%20Covid-19-related%20lockdown%20included%20the%20closing%20of%20kindergartens%20and%20schools.%20Home%20schooling%2C%20the%20lack%20of%20social%20contacts%20with%20peers%20and%20the%20care%20of%20the%20children%20at%20home%20posed%20an%20enormous%20challenge%20for%20many%20families.%5CnMETHODS%3A%20The%20present%20study%20investigated%20the%20leisure%20behavior%20of%20285%20one-%20to%2010-year-old%20German%20children%20at%20two%20time%20points%20%28t1%20and%20t2%29%20during%20the%20Covid-19-related%20lockdown%20in%20spring%202020.%20In%20the%20subsample%20of%20primary%20school%20children%20%28n%20%3D%20102%29%2C%20we%20also%20explored%20children%27s%20attitudes%20towards%20schoolwork%20at%20home.%20Analyses%20focused%20on%20the%20change%20of%20behavior%20from%20t1%20to%20t2%2C%20on%20differences%20in%20these%20changes%20depending%20on%20socio-economic%20status%20%28SES%29%2C%20and%20on%20associations%20of%20behavior%20with%20SES%2C%20the%20number%20of%20children%20at%20home%2C%20and%20the%20frequency%20of%20receiving%20learning%20materials%20from%20school.%5CnRESULTS%3A%20While%20the%20frequency%20of%20playing%20outside%20increased%20significantly%20from%20t1%20to%20t2%2C%20the%20frequency%20of%20handicrafts%2C%20playing%20board%20games%2C%20indoor%20sports%2C%20and%20motivation%20to%20do%20schoolwork%20decreased.%20The%20observed%20changes%20between%20t1%20and%20t2%20did%20not%20differ%20depending%20on%20SES.%20However%2C%20a%20lower%20SES%20was%20associated%20with%20higher%20media%20use%2C%20less%20outdoor%20activity%2C%20and%20%28though%20only%20marginally%20significant%29%20a%20reduced%20time%20doing%20schoolwork%20and%20a%20reduced%20ability%20to%20concentrate%20on%20schoolwork%20at%20t1.%20In%20households%20with%20more%20children%2C%20children%20played%20outside%20more%20often%2C%20but%20were%20read%20to%20less%20frequently%20and%20%28though%20only%20marginally%20significant%29%20watched%20movies%20and%20series%20less%20frequently.%20Children%20receiving%20learning%20materials%20from%20school%20on%20a%20regular%20basis%20spent%20significantly%20more%20time%20doing%20schoolwork%20at%20home%20than%20children%20receiving%20materials%20only%20irregularly.%5CnCONCLUSIONS%3A%20A%20continuing%20loss%20of%20childcare%20in%20day-care%20facilities%20and%20schools%20entails%20the%20danger%20of%20declining%20education%20in%20the%20form%20of%20%28inter%29active%20indoor%20activities%20and%20schoolwork.%22%2C%22date%22%3A%222021-03%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1371%5C%2Fjournal.pone.0247949%22%2C%22ISSN%22%3A%221932-6203%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1371%5C%2Fjournal.pone.0247949%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-24T11%3A01%3A24Z%22%7D%7D%2C%7B%22key%22%3A%226AVE9W3V%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Vogel%20et%20al.%22%2C%22parsedDate%22%3A%222021-03%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EVogel%2C%20Mandy%2C%20Christof%20Meigen%2C%20Carolin%20Sobek%2C%20Peggy%20Ober%2C%20Ulrike%20Igel%2C%20Antje%20K%26%23xF6%3Brner%2C%20Wieland%20Kiess%2C%20and%20Tanja%20Poulain.%20%26%23x201C%3BWell-Being%20and%20Covid-19-Related%20Worries%20of%20German%20Children%20and%20Adolescents%3A%20A%20Longitudinal%20Study%20from%20Pre-Covid%20to%20the%20End%20of%20Lockdown%20in%20Spring%202020.%26%23x201D%3B%20%3Ci%3EJCPP%20Advances%3C%5C%2Fi%3E%201%2C%20no.%201%20%28March%202021%29%3A%20e12004.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fjcv2.12004%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fjcv2.12004%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Well-Being%20and%20Covid-19-Related%20Worries%20of%20German%20Children%20and%20Adolescents%3A%20A%20Longitudinal%20Study%20from%20Pre-Covid%20to%20the%20End%20of%20Lockdown%20in%20Spring%202020%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christof%22%2C%22lastName%22%3A%22Meigen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Carolin%22%2C%22lastName%22%3A%22Sobek%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Peggy%22%2C%22lastName%22%3A%22Ober%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ulrike%22%2C%22lastName%22%3A%22Igel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%5D%2C%22abstractNote%22%3A%22Background%20There%20is%20concern%20that%20pandemic%20measures%20put%20a%20strain%20on%20the%20health%20and%20well-being%20of%20children.%20We%20investigated%20the%20effects%20of%20the%20COVID-19%20pandemic%2C%20the%20lockdown%2C%20and%20social%20distancing%20on%20the%20well-being%2C%20media%20use%2C%20and%20emotions%20of%20children%20and%20adolescents%20between%209%20and%2018%20years.%20Methods%20We%20used%20linear%20and%20proportional%20odds%20logistic%20regression%20correcting%20for%20age%2C%20sex%2C%20and%20socioeconomic%20status%20%28SES%29%20and%20to%20compare%20media%20use%2C%20peers%5C%2Fsocial%20support%2C%20physical%2C%20and%20psychological%20well-being%20between%202019%20%28pre-COVID%20baseline%29%20and%20two%20time%20points%20shortly%20after%20the%20start%20of%20the%20lockdown%20%28last%20week%20of%20March%20and%20April%202020%2C%20respectively%29%20in%20391%209%5Cu201319-year-old%20healthy%20children%20and%20adolescents%20of%20the%20LIFE%20Child%20cohort.%20COVID-19-related%20feelings%20and%20their%20relationship%20to%20age%2C%20sex%2C%20and%20SES%20were%20assessed%20at%20two%20time%20points%20during%20lockdown.%20Results%20We%20found%20significantly%20lower%20scores%20in%20physical%20and%20psychological%20well-being%20during%20lockdown%20compared%20to%20baseline.%20The%20effect%20was%20significantly%20stronger%20in%20children%20with%20medium%5C%2Flow%20SES.%20Perceived%20social%20support%20scores%20were%20also%20significantly%20lower%20during%20the%20lockdown.%20The%20percentage%20of%20children%20who%20had%20no%20contact%20with%20their%20peers%20%28in-person%20or%20online%29%20increased%20from%203%25%20pre-COVID%20to%2014%25%20and%2013%25%20in%20April%20and%20March%202020%2C%20respectively.%20About%2080%25%20of%20the%20children%20missed%20in-person%20contacts%20with%20friends.%20Most%20of%20the%20children%20worried%20more%20about%20the%20health%20of%20their%20families%20than%20their%20own.%20Sixty%20percent%20worried%20about%20the%20international%20situation%20at%20least%20moderately%2C%20whereas%20only%2020%25%20were%20afraid%20of%20COVID-19%20itself.%20The%20percentage%20of%20children%20who%20believed%20it%20would%20never%20be%20as%20before%20COVID-19%20rose%20from%207.4%25%20at%20the%20beginning%20lockdown%20end%20of%20March%20to%2016.2%25%20a%20month%20later.%20In%20contrast%2C%20all%20other%20COVID-19-related%20worries%2C%20showed%20a%20%28nonsignificant%29%20decline%20during%20the%20same%20period.%20Conclusion%20Our%20study%20supports%20the%20notion%20that%20pandemic%20measures%20have%20to%20be%20balanced%20against%20adverse%20public%20health%20effects.%20Especially%20vulnerable%20groups%20have%20to%20be%20protected.%22%2C%22date%22%3A%222021-03%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1111%5C%2Fjcv2.12004%22%2C%22ISSN%22%3A%222692-9384%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Facamh.onlinelibrary.wiley.com%5C%2Fdoi%5C%2Fabs%5C%2F10.1111%5C%2Fjcv2.12004%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-24T13%3A37%3A39Z%22%7D%7D%2C%7B%22key%22%3A%222RJTVGA9%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Brandstetter%20et%20al.%22%2C%22parsedDate%22%3A%222020-10-06%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EBrandstetter%2C%20Susanne%2C%20Tanja%20Poulain%2C%20Mandy%20Vogel%2C%20Christof%20Meigen%2C%20Michael%20Melter%2C%20Birgit%20Seelbach-G%26%23xF6%3Bbel%2C%20Christian%20Apfelbacher%2C%20et%20al.%20%26%23x201C%3BThe%20Impact%20of%20the%20Covid-19%20Pandemic%20on%20Families%20in%20Germany.%26%23x201D%3B%20%3Ci%3EMedRxiv%3C%5C%2Fi%3E%2C%20October%206%2C%202020%2C%202020.10.05.20206805.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1101%5C%2F2020.10.05.20206805%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1101%5C%2F2020.10.05.20206805%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22The%20Impact%20of%20the%20Covid-19%20Pandemic%20on%20Families%20in%20Germany%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Susanne%22%2C%22lastName%22%3A%22Brandstetter%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christof%22%2C%22lastName%22%3A%22Meigen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Michael%22%2C%22lastName%22%3A%22Melter%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Birgit%22%2C%22lastName%22%3A%22Seelbach-G%5Cu00f6bel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christian%22%2C%22lastName%22%3A%22Apfelbacher%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Michael%22%2C%22lastName%22%3A%22Kabesch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22the%20KUNO%20Kids%20study%22%2C%22lastName%22%3A%22Group%22%7D%5D%2C%22abstractNote%22%3A%22Objective%3A%20To%20assess%20the%20impact%20of%20the%20COVID-19%20pandemic%20on%20families%20with%20young%20children%20in%20two%20population-based%20childhood%20cohorts%20with%20a%20low%20and%20moderate%20COVID-19%20prevalence%2C%20respectively.%20Methods%3A%20A%20cross-sectional%20study%20using%20online%20questionnaires%20in%20families%20from%20LIFE%20Child%20%28n%3D306%2C%20Leipzig%29%20and%20KUNO%20Kids%20%28n%3D612%2C%20Regensburg%29%20was%20performed%20at%20the%20end%20of%20the%20German%20lock-down%20period.%20Outcomes%20were%20parent-reported%20impact%20of%20the%20COVID-19%20pandemic%20on%20family%20life%2C%20concerns%20and%20trust%20in%20political%20measures.%20Results%3A%20Most%20families%20were%20concerned%20about%20the%20COVID-19%20pandemic%20and%20lock-down%20measures%2C%20with%20major%20concerns%20directed%20towards%20the%20economic%20situation%20%28%26gt%3B70%25%29%2C%20the%20health%20of%20close-ones%20%2837%25%29%2C%20but%20less%20towards%20their%20own%20health%20%28%26lt%3B10%25%29.%20Many%20concerns%2C%20seeking%20information%20and%20approval%20of%20federal%20measures%20were%20more%20pronounced%20in%20the%20more%20affected%20region.%20Approval%20of%20lockdown%20measures%20and%20concerns%20about%20economic%20recession%20were%20related%20to%20regional%20differences%20and%20not%20significantly%20dependent%20on%20educational%20status%20or%20being%20personally%20affected%20by%20the%20disease.%20Conclusion%3A%20Regional%20differences%20in%20approval%20of%20lockdown%20measures%20were%20observed%20and%20thus%2C%20measures%20to%20specifically%20support%20families%20according%20to%20the%20regional%20impact%20of%20the%20COVID-19%20pandemic%20are%20needed.%22%2C%22date%22%3A%222020-10-06%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1101%5C%2F2020.10.05.20206805%22%2C%22ISSN%22%3A%22%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.medrxiv.org%5C%2Fcontent%5C%2F10.1101%5C%2F2020.10.05.20206805v1%22%2C%22collections%22%3A%5B%22GQV6TIX2%22%2C%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-07T07%3A01%3A54Z%22%7D%7D%5D%7D
Poulain, Tanja, Christof Meigen, Wieland Kiess, and Mandy Vogel. “An Online Survey Carried Out in 2022 Showed That Covid-19 Was Associated with Negative Changes in Children’s Lives.” Acta Paediatrica (Oslo, Norway: 1992), June 2, 2022. https://doi.org/10.1111/apa.16435.
Kiess, Wieland, Anna S. Kirstein, Robert Stein, and Mandy Vogel. “Obesity After the Covid-19 Pandemic and Beyond.” Journal of Pediatric Endocrinology and Metabolism 35, no. 2 (February 2022): 135–38. https://doi.org/10.1515/jpem-2022-2135.
Brandstetter, Susanne, Tanja Poulain, Mandy Vogel, Christof Meigen, Michael Melter, Angela Köninger, Christian Apfelbacher, et al. “Families’ Worries During the First and Second Covid-19 Wave in Germany: Longitudinal Study in Two Population-Based Cohorts.” International Journal of Environmental Research and Public Health 19, no. 5 (January 2022): 2820. https://doi.org/10.3390/ijerph19052820.
Jurkutat, Anne, Christof Meigen, Melanie Maier, Nico Grafe, Uwe G. Liebert, and Wieland Kiess. “Screening for Sars-Cov-2 in Non-Symptomatic Students and Staff Shows Safe School Openings Under Varying Incidence with Sufficient Mandatory Measures.” Acta Paediatrica (Oslo, Norway: 1992) online ahead of print (January 2022). https://doi.org/https://doi.org/10.1111/apa.16245.
Vogel, Mandy, Mandy Geserick, Ruth Gausche, Christoph Beger, Tanja Poulain, Christof Meigen, Antje Körner, Eberhard Keller, Wieland Kiess, and Roland Pfäffle. “Age- and Weight Group-Specific Weight Gain Patterns in Children and Adolescents During the 15 Years Before and During the Covid-19 Pandemic.” International Journal of Obesity (2005) 46, no. 1 (January 2022): 144–52. https://doi.org/10.1038/s41366-021-00968-2.
Vogel, Mandy, Mandy Geserick, Ruth Gausche, Christoph Beger, Tanja Poulain, Christof Meigen, Antje Körner, et al. “Gewichtszunahme Bei Kindern Und Jugendlichen Während Der Covid-19-Pandemie.” Kinder- Und Jugendmedizin 22, no. 2 (2022): 112–17. https://doi.org/10.1055/a-1732-1623.
Vogel, Mandy, Christoph Beger, Ruth Gausche, Anne Jurkutat, Roland Pfaeffle, Antje Körner, Christof Meigen, Tanja Poulain, and Wieland Kiess. “Covid-19 Pandemic and Families’ Utilization of Well-Child Clinics and Pediatric Practices Attendance in Germany.” BMC Research Notes 14, no. 1 (April 2021): 140. https://doi.org/10.1186/s13104-021-05562-3.
Kiess, Wieland, Tanja Poulain, Anne Jurkutat, Anna Kirstein, and Mandy Vogel. “Covid19 Pandemic and Pediatric Endocrinology and Metabolism-Are We Through with It?” Journal of Pediatric Endocrinology & Metabolism: JPEM 34, no. 5 (April 2021): 535–37. https://doi.org/10.1515/jpem-2021-2133.
Poulain, Tanja, Christof Meigen, Carolin Sobek, Peggy Ober, Ulrike Igel, Antje Körner, Wieland Kiess, and Mandy Vogel. “Loss of Childcare and Classroom Teaching During the Covid-19-Related Lockdown in Spring 2020: A Longitudinal Study on Consequences on Leisure Behavior and Schoolwork at Home.” PloS One 16, no. 3 (March 2021): e0247949. https://doi.org/10.1371/journal.pone.0247949.
Vogel, Mandy, Christof Meigen, Carolin Sobek, Peggy Ober, Ulrike Igel, Antje Körner, Wieland Kiess, and Tanja Poulain. “Well-Being and Covid-19-Related Worries of German Children and Adolescents: A Longitudinal Study from Pre-Covid to the End of Lockdown in Spring 2020.” JCPP Advances 1, no. 1 (March 2021): e12004. https://doi.org/10.1111/jcv2.12004.
Brandstetter, Susanne, Tanja Poulain, Mandy Vogel, Christof Meigen, Michael Melter, Birgit Seelbach-Göbel, Christian Apfelbacher, et al. “The Impact of the Covid-19 Pandemic on Families in Germany.” MedRxiv, October 6, 2020, 2020.10.05.20206805. https://doi.org/10.1101/2020.10.05.20206805.
2390247
T52N9QLZ
SES
1
chicago-fullnote-bibliography
50
date
desc
1
1
6748
https://home.uni-leipzig.de/lifechild/wp-content/plugins/zotpress/
%7B%22status%22%3A%22success%22%2C%22updateneeded%22%3Afalse%2C%22instance%22%3Afalse%2C%22meta%22%3A%7B%22request_last%22%3A0%2C%22request_next%22%3A0%2C%22used_cache%22%3Atrue%7D%2C%22data%22%3A%5B%7B%22key%22%3A%22A8SXRF42%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Petri%20et%20al.%22%2C%22parsedDate%22%3A%222024%22%2C%22numChildren%22%3A2%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EPetri%2C%20Laura%2C%20Tanja%20Poulain%2C%20Mandy%20Vogel%2C%20Christof%20Meigen%2C%20Wieland%20Kiess%2C%20and%20Andreas%20Hiemisch.%20%26%23x201C%3BParent-Perceived%20Recurrent%20Pain%20in%20Children%3A%20Associations%20with%20Maternal%20Pain%2C%20Depressiveness%2C%20Socioeconomic%20Status%2C%20and%20Children%26%23×2019%3Bs%20Behavioural%20Difficulties.%26%23x201D%3B%20%3Ci%3EFrontiers%20in%20Pediatrics%3C%5C%2Fi%3E%2012%20%282024%29%3A%201287343.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3389%5C%2Ffped.2024.1287343%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3389%5C%2Ffped.2024.1287343%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Parent-perceived%20recurrent%20pain%20in%20children%3A%20associations%20with%20maternal%20pain%2C%20depressiveness%2C%20socioeconomic%20status%2C%20and%20children%27s%20behavioural%20difficulties%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Laura%22%2C%22lastName%22%3A%22Petri%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christof%22%2C%22lastName%22%3A%22Meigen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andreas%22%2C%22lastName%22%3A%22Hiemisch%22%7D%5D%2C%22abstractNote%22%3A%22OBJECTIVES%3A%20The%20current%20study%20aimed%20to%20examine%20the%20potential%20transgenerational%20associations%20between%20maternal%20pain%20and%20depressiveness%20and%20childhood%20pain%2C%20and%20to%20explore%20the%20associations%20between%20the%20children%27s%20difficulties%20and%20recurrent%20pain%20%28defined%20as%20pain%20occurring%20at%20least%20once%20a%20month%20in%20the%20previous%206%20month%29%20in%20healthy%20children%20aged%203-13%20years.%5CnMETHODS%3A%20We%20collected%20Data%20between%202015%20and%202019%20as%20part%20of%20the%20LIFE%20Child%20study%20in%20Germany%20and%20investigated%20associations%20of%20maternal%20pain%20and%20depressiveness%2C%20child%20age%2C%20sex%2C%20pubertal%20stage%2C%20emotional%20difficulties%2C%20conduct%20difficulties%2C%20hyperactivity%5C%2Finattention%2C%20peer%20group%20difficulties%2C%20and%20prosocial%20skills%2C%20and%20family%20socioeconomic%20status%20with%20the%20frequency%20of%20parent-perceived%20headache%2C%20backache%2C%20and%20stomachache%20in%20a%20sample%20of%201%2C850%20children%20%284%2C819%20documented%20visits%29%20using%20logistic%20and%20ordinal%20regression%20analyses.%5CnRESULTS%3A%20Overall%2C%2010.4%25%2C%2024.4%25%2C%20and%2045.2%25%20of%20parents%20reported%20their%20children%20had%20recurrent%20backache%2C%20headache%2C%20and%20stomachache%2C%20respectively%2C%20with%205.5%25%20of%20children%20were%20reported%20to%20experience%20all%20three%20types%20of%20pain%20simultaneously.%20Higher%20age%2C%20female%20sex%2C%20puberty%2C%20emotional%20difficulties%2C%20low%20family%20socioeconomic%20status%2C%20as%20well%20as%20higher%20maternal%20impairment%20due%20to%20pain%20and%20maternal%20depressiveness%20were%20significantly%20associated%20with%20more%20frequent%20pain.%5CnCONCLUSIONS%3A%20Our%20study%20suggests%20that%20maternal%20pain%2C%20maternal%20depressiveness%2C%20and%20lower%20family%20socioeconomic%20status%20as%20well%20as%20child%27s%20emotional%20difficulties%20are%20significantly%20associated%20with%20a%20higher%20frequency%20of%20recurrent%20pain%20in%20children%20perceived%20by%20their%20parents.%22%2C%22date%22%3A%222024%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.3389%5C%2Ffped.2024.1287343%22%2C%22ISSN%22%3A%222296-2360%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222024-08-27T12%3A40%3A19Z%22%7D%7D%2C%7B%22key%22%3A%22D3U7X6PF%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Gr%5Cu00fcning%20Parache%20et%20al.%22%2C%22parsedDate%22%3A%222023-12-26%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EGr%26%23xFC%3Bning%20Parache%2C%20Laura%2C%20Mandy%20Vogel%2C%20Christof%20Meigen%2C%20Wieland%20Kiess%2C%20and%20Tanja%20Poulain.%20%26%23x201C%3BFamily%20Structure%2C%20Socioeconomic%20Status%2C%20and%20Mental%20Health%20in%20Childhood.%26%23x201D%3B%20%3Ci%3EEuropean%20Child%20%26amp%3B%20Adolescent%20Psychiatry%3C%5C%2Fi%3E%2C%20December%2026%2C%202023.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs00787-023-02329-y%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs00787-023-02329-y%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Family%20structure%2C%20socioeconomic%20status%2C%20and%20mental%20health%20in%20childhood%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Laura%22%2C%22lastName%22%3A%22Gr%5Cu00fcning%20Parache%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christof%22%2C%22lastName%22%3A%22Meigen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%5D%2C%22abstractNote%22%3A%22The%20changing%20landscape%20of%20family%20structures%20over%20the%20last%20decades%20has%20led%20to%20a%20growing%20need%20to%20investigate%20its%20impact%20on%20children%27s%20well-being.%20This%20study%20examined%20differences%20in%20mental%20health%20among%20children%20from%20different%20family%20compositions%20and%20how%20these%20differences%20may%20be%20affected%20by%20familial%20socioeconomic%20status%20%28SES%29.%20Data%20were%20collected%20within%20the%20LIFE%20Child%20study.%20Participants%20included%202828%20children%20aged%203-17%5Cu00a0years%20raised%20in%20traditional%20families%2C%20stepfamilies%2C%20or%20single-parent%20families.%20Mental%20health%20was%20measured%20using%20the%20Strengths%20and%20Difficulties%20Questionnaire%20%28SDQ%20%28behavioral%20strengths%20and%20difficulties%29%29%20and%20the%20KIDSCREEN-27%20questionnaire%20%28quality%20of%20life%29.%20Linear%20regression%20analyses%20were%20applied%20to%20examine%20associations%20between%20family%20structure%2C%20SES%2C%20and%20mental%20health%20outcomes.%20Children%20from%20single-parent%20families%20exhibited%20worse%20mental%20health%20outcomes%20than%20those%20from%20traditional%20families%20across%20all%20domains%20of%20the%20SDQ%20and%20the%20KIDSCREEN-27.%20Children%20from%20stepfamilies%20showed%20significantly%20higher%20Total%20Difficulties%20scores%20%28B%5Cu2009%3D%5Cu20091.29%20and%201.42%29%2C%20with%203-%20to%2010-year-olds%20displaying%20higher%20scores%20in%20the%20Hyperactivity%20%26%20Inattention%20%28B%5Cu2009%3D%5Cu20090.61%29%20and%20Peer%20Relationship%20Problems%20%28B%5Cu2009%3D%5Cu20090.36%29%20subscales%2C%20and%2011-%20to%2017-year-olds%20showing%20higher%20Conduct%20Problems%20%28B%5Cu2009%3D%5Cu20090.31%29%2C%20Emotional%20Symptoms%20%28B%5Cu2009%3D%5Cu20090.58%29%2C%20and%20a%20worse%20Parent%20Relationship%20scores%20%28B%5Cu2009%3D%5Cu2009-%5Cu00a01.82%29%20than%20children%20from%20traditional%20families%20%28all%20p%5Cu2009%3C%5Cu20090.05%29.%20After%20controlling%20for%20SES%2C%20several%20associations%20between%20family%20structure%20and%20mental%20health%20lost%20significance%2C%20while%20others%20persisted%2C%20particularly%20among%20older%20children.%20To%20promote%20mental%20health%20in%20non-traditional%20families%2C%20interventions%20should%20address%20socioeconomic%20disparities%20while%20also%20investigating%20factors%20contributing%20to%20the%20direct%20impact%20of%20family%20structure%20on%20mental%20well-being.Trial%20registration%20The%20LIFE%20Child%20study%20is%20registered%20on%20clinicaltrials.gov%20%28No.%20NCT02550236%29.%22%2C%22date%22%3A%222023-12-26%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1007%5C%2Fs00787-023-02329-y%22%2C%22ISSN%22%3A%221435-165X%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-12-28T07%3A09%3A36Z%22%7D%7D%2C%7B%22key%22%3A%2298ACU36I%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Dathan-Stumpf%20et%20al.%22%2C%22parsedDate%22%3A%222023-03-02%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EDathan-Stumpf%2C%20Anne%2C%20Mandy%20Vogel%2C%20Nico%20Grafe%2C%20Wieland%20Kiess%2C%20and%20Holger%20Stepan.%20%26%23x201C%3BRelation%20between%20Socioeconomic%20Status%20and%20Maternal%20Serum%20Lipids%20to%20Infant%20Lipid%20Concentrations%20and%20Anthropometry%20in%20the%20First%20Year%20of%20Life.%26%23x201D%3B%20%3Ci%3EArchives%20of%20Gynecology%20and%20Obstetrics%3C%5C%2Fi%3E%2C%20March%202%2C%202023.%20%3Ca%20class%3D%27zp-ItemURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs00404-023-06937-6%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs00404-023-06937-6%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Relation%20between%20socioeconomic%20status%20and%20maternal%20serum%20lipids%20to%20infant%20lipid%20concentrations%20and%20anthropometry%20in%20the%20first%20year%20of%20life%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anne%22%2C%22lastName%22%3A%22Dathan-Stumpf%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Nico%22%2C%22lastName%22%3A%22Grafe%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Holger%22%2C%22lastName%22%3A%22Stepan%22%7D%5D%2C%22abstractNote%22%3A%22The%20physical%20health%20and%20development%20of%20an%20individual%20are%20influenced%20by%20multiple%20parameters%20and%20shaped%20by%20internal%20and%20external%20factors%20during%20pregnancy.%20However%2C%20it%20is%20unclear%20whether%20there%20is%20an%20association%20between%20maternal%20lipid%20concentrations%20in%20the%20third%20trimester%20of%20pregnancy%20and%20infant%20serum%20lipids%20as%20well%20as%20anthropometric%20growth%2C%20and%20whether%20these%20factors%20are%20influenced%20by%20the%20socioeconomic%20status%20%28SES%29%20of%20the%20mothers.%22%2C%22date%22%3A%222023-03-02%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1007%5C%2Fs00404-023-06937-6%22%2C%22ISSN%22%3A%221432-0711%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs00404-023-06937-6%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-23T12%3A21%3A59Z%22%7D%7D%2C%7B%22key%22%3A%22J6B8PXY7%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Philipp%20et%20al.%22%2C%22parsedDate%22%3A%222022-11-10%22%2C%22numChildren%22%3A2%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EPhilipp%2C%20Dariusch%2C%20Mandy%20Vogel%2C%20Manuela%20Brandt%2C%20Franziska%20G.%20Rauscher%2C%20Andreas%20Hiemisch%2C%20Siegfried%20Wahl%2C%20Wieland%20Kiess%2C%20and%20Tanja%20Poulain.%20%26%23x201C%3BThe%20Relationship%20between%20Myopia%20and%20near%20Work%2C%20Time%20Outdoors%20and%20Socioeconomic%20Status%20in%20Children%20and%20Adolescents.%26%23x201D%3B%20%3Ci%3EBMC%20Public%20Health%3C%5C%2Fi%3E%2022%2C%20no.%201%20%28November%2010%2C%202022%29%3A%202058.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs12889-022-14377-1%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs12889-022-14377-1%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22The%20relationship%20between%20myopia%20and%20near%20work%2C%20time%20outdoors%20and%20socioeconomic%20status%20in%20children%20and%20adolescents%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Dariusch%22%2C%22lastName%22%3A%22Philipp%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Manuela%22%2C%22lastName%22%3A%22Brandt%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Franziska%20G.%22%2C%22lastName%22%3A%22Rauscher%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andreas%22%2C%22lastName%22%3A%22Hiemisch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Siegfried%22%2C%22lastName%22%3A%22Wahl%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%5D%2C%22abstractNote%22%3A%22BACKGROUND%3A%20To%20investigate%20environmental%20and%20social%20risk%20factors%20for%20myopia%20in%20children%20and%20adolescents%20in%20Germany.%5CnMETHODS%3A%201437%20children%20aged%20between%203%20and%2018%20inclusive%20were%20examined%20as%20part%20of%20the%20LIFE%20Child%20study%20based%20in%20Leipzig%2C%20Germany.%20Information%20about%20leisure%20time%20activities%20and%20social%20status%20was%20ascertained%20by%20parents%20and%20children%20in%20a%20questionnaire.%20Refractive%20status%20was%20attained%20by%20measuring%20noncycloplegic%20autorefraction.%20Myopia%20was%20defined%20as%20spherical%20equivalent%20%28SE%29%5Cu2009%5Cu2264%5Cu2009-%5Cu20090.75%20D.%20Risk%20factors%20were%20identified%20using%20multiple%20logistic%20regression%20analysis.%5CnRESULTS%3A%20In%20multiple%20logistic%20regression%20analysis%2C%20myopia%20was%20significantly%20associated%20with%20less%20frequent%20outdoor%20activity%20%28%5C%22once%20a%20week%5C%22%20vs.%20%5C%22twice%20a%20week%20or%20more%5C%22%3A%20odds%20ratio%20%28OR%29%204.35%2C%2095%25%20confidence%20interval%20%28CI%29%201.89-9.98%2C%20p%26lt%3B0.01%29%20and%20longer%20near%20work%20sessions%20%281-2%5Cu00a0h%20vs.%20%26lt%3B%201%5Cu00a0h%3A%20OR%201.83%2C%20CI%201.10-3.04%2C%20p%3D0.02%3B%20%26gt%3B%203%5Cu00a0h%20vs.%20%26lt%3B%201%5Cu00a0h%3A%20OR%203.71%2C%20CI%201.43-9.61%2C%20p%26lt%3B0.01%29%20after%20adjustment%20for%20age%2C%20sex%20and%20socioeconomic%20status%20%28SES%29.%20Duration%20of%20outdoor%20activity%2C%20near%20work%20frequency%20and%20SES%20showed%20no%20significant%20association%20with%20myopia%20%28p%5Cu2009%26gt%3B%5Cu20090.05%29.%20Children%20with%20a%20lower%20SES%20were%20involved%20in%20longer%20periods%20of%20outdoor%20and%20near%20work%20activities%20but%20on%20fewer%20occasions%20over%20the%20course%20of%20the%20week%2C%20although%20this%20connection%20was%20not%20significant.%5CnCONCLUSION%3A%20Myopia%20is%20associated%20with%20environmental%20factors.%20The%20present%20findings%20suggest%20that%20daily%20exposure%20to%20sunlight%20and%20a%20restriction%20of%20long-duration%20near%20work%20activities%20might%20protect%20against%20pathological%20eye%20growth.%20Prevention%20strategies%20should%20be%20implemented%20for%20children%20at%20all%20ages.%22%2C%22date%22%3A%222022-11-10%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1186%5C%2Fs12889-022-14377-1%22%2C%22ISSN%22%3A%221471-2458%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222024-08-27T13%3A13%3A26Z%22%7D%7D%2C%7B%22key%22%3A%22BDD7FQLL%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Schild%20et%20al.%22%2C%22parsedDate%22%3A%222022-11-01%22%2C%22numChildren%22%3A2%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3ESchild%2C%20Clara%20Elise%2C%20Christof%20Meigen%2C%20Jonas%20Kappelt%2C%20Wieland%20Kiess%2C%20and%20Tanja%20Poulain.%20%26%23x201C%3BAssociations%20between%20Sociodemographic%20and%20Behavioural%20Parameters%20and%20Child%20Development%20Depending%20on%20Age%20and%20Sex%3A%20A%20Cross-Sectional%20Analysis.%26%23x201D%3B%20%3Ci%3EBMJ%20Open%3C%5C%2Fi%3E%2012%2C%20no.%2011%20%28November%201%2C%202022%29%3A%20e065936.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1136%5C%2Fbmjopen-2022-065936%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1136%5C%2Fbmjopen-2022-065936%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Associations%20between%20sociodemographic%20and%20behavioural%20parameters%20and%20child%20development%20depending%20on%20age%20and%20sex%3A%20a%20cross-sectional%20analysis%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Clara%20Elise%22%2C%22lastName%22%3A%22Schild%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christof%22%2C%22lastName%22%3A%22Meigen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jonas%22%2C%22lastName%22%3A%22Kappelt%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%5D%2C%22abstractNote%22%3A%22Objectives%20To%20explore%20environmental%20and%20individual%20factors%20that%20are%20associated%20with%20child%20development%20and%20to%20investigate%20whether%20the%20strength%20of%20these%20associations%20differs%20according%20to%20the%20age%20of%20the%20children.%5CnDesign%20Cross-sectional%20study.%5CnSetting%20This%20study%20was%20part%20of%20the%20LIFE%20Child%20study%2C%20a%20large%20cohort%20study%20conducted%20in%20Leipzig%2C%20Germany.%5CnParticipants%20778%20children%20aged%20between%200.5%20and%206%20years%20%2848.6%25%20girls%2C%20mean%20age%3D2.67%20years%29.%5CnOutcome%20measures%20The%20outcomes%20were%20cognitive%20development%2C%20language%20development%2C%20body%20and%20hand%20motor%20skills%2C%20social-emotional%20development%2C%20and%20tracing%20skills%2C%20measured%20with%20a%20standardised%20development%20test.%20We%20analysed%20the%20associations%20between%20development%20and%20gestational%20age%2C%20socioeconomic%20status%20%28SES%29%2C%20sex%2C%20behavioural%20difficulties%2C%20siblings%2C%20sleep%20duration%2C%20breastfeeding%20duration%20and%20overweight%5C%2Fobesity.%20We%20also%20tested%20for%20interactions%20between%20these%20variables%20and%20child%20age%20or%20sex.%5CnResults%20Higher%20gestational%20age%20%28b%20ranging%20between%200.12%20and%200.26%29%20and%20higher%20SES%20%28b%20ranging%20between%200.08%20and%200.21%29%20were%20associated%20with%20better%20outcomes%20in%20almost%20all%20developmental%20domains%20%28all%20p%3C0.019%29.%20Children%20with%20older%20siblings%20had%20improved%20body%20and%20hand%20motor%20skills%20compared%20with%20children%20without%20older%20siblings%20%28both%20b%3D0.55%2C%20all%20p%3C0.029%29.%20Boys%20had%20poorer%20scores%20than%20girls%20in%20body%20and%20hand%20motor%20skills%20and%20tracing%20%28b%3D%5Cu22120.45%2C%20%5Cu22120.68%20and%20%5Cu22121.5%2C%20all%20p%3C0.019%29.%20Children%20with%20behavioural%20difficulties%20had%20significantly%20poorer%20outcomes%20in%20most%20developmental%20domains.%20Some%20of%20the%20associations%20with%20SES%20and%20sex%20were%20stronger%20in%20older%20than%20in%20younger%20children.%20Associations%20between%20gestational%20age%20and%20motor%20development%20were%20weaker%20in%20older%20children.%20We%20did%20not%20find%20significant%20associations%20between%20child%20development%20and%20sleep%20duration%2C%20breastfeeding%20duration%20or%20overweight%5C%2Fobesity.%5CnConclusion%20Some%20factors%20had%20a%20protective%2C%20others%20an%20adverse%20effect%20on%20development%20of%20children%20under%206%20years%20of%20age.%20The%20effect%20of%20SES%20and%20sex%20increased%2C%20while%20the%20effect%20of%20gestational%20age%20decreased%20with%20age.%5CnTrial%20registration%20number%20NCT02550236.%22%2C%22date%22%3A%222022%5C%2F11%5C%2F01%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1136%5C%2Fbmjopen-2022-065936%22%2C%22ISSN%22%3A%222044-6055%2C%202044-6055%22%2C%22url%22%3A%22http%3A%5C%2F%5C%2Fbmjopen.bmj.com%5C%2Fcontent%5C%2F12%5C%2F11%5C%2Fe065936%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-07T07%3A01%3A28Z%22%7D%7D%2C%7B%22key%22%3A%22VW9I9DSC%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Poulain%20et%20al.%22%2C%22parsedDate%22%3A%222022-06-02%22%2C%22numChildren%22%3A3%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EPoulain%2C%20Tanja%2C%20Christof%20Meigen%2C%20Wieland%20Kiess%2C%20and%20Mandy%20Vogel.%20%26%23x201C%3BAn%20Online%20Survey%20Carried%20Out%20in%202022%20Showed%20That%20Covid-19%20Was%20Associated%20with%20Negative%20Changes%20in%20Children%26%23×2019%3Bs%20Lives.%26%23x201D%3B%20%3Ci%3EActa%20Paediatrica%20%28Oslo%2C%20Norway%3A%201992%29%3C%5C%2Fi%3E%2C%20June%202%2C%202022.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fapa.16435%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fapa.16435%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22An%20Online%20Survey%20Carried%20Out%20in%202022%20Showed%20That%20Covid-19%20Was%20Associated%20with%20Negative%20Changes%20in%20Children%27s%20Lives%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christof%22%2C%22lastName%22%3A%22Meigen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%5D%2C%22abstractNote%22%3A%22%22%2C%22date%22%3A%222022-06-02%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1111%5C%2Fapa.16435%22%2C%22ISSN%22%3A%221651-2227%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-24T11%3A00%3A36Z%22%7D%7D%2C%7B%22key%22%3A%22R2F3DZ8S%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Schmidt%20et%20al.%22%2C%22parsedDate%22%3A%222022-01%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3ESchmidt%2C%20Jana%2C%20Mandy%20Vogel%2C%20Tanja%20Poulain%2C%20Wieland%20Kiess%2C%20Christian%20Hirsch%2C%20Dirk%20Ziebolz%2C%20and%20Rainer%20Haak.%20%26%23x201C%3BAssociation%20of%20Oral%20Health%20Conditions%20in%20Adolescents%20with%20Social%20Factors%20and%20Obesity.%26%23x201D%3B%20%3Ci%3EInternational%20Journal%20of%20Environmental%20Research%20and%20Public%20Health%3C%5C%2Fi%3E%2019%2C%20no.%205%20%28January%202022%29%3A%202905.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Fijerph19052905%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Fijerph19052905%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Association%20of%20Oral%20Health%20Conditions%20in%20Adolescents%20with%20Social%20Factors%20and%20Obesity%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jana%22%2C%22lastName%22%3A%22Schmidt%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christian%22%2C%22lastName%22%3A%22Hirsch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Dirk%22%2C%22lastName%22%3A%22Ziebolz%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Rainer%22%2C%22lastName%22%3A%22Haak%22%7D%5D%2C%22abstractNote%22%3A%22This%20study%20aimed%20to%20investigate%20associations%20between%20psychosocial%20factors%2C%20obesity%2C%20and%20oral%20health%20in%20a%20study%20population%20of%2010-%20to%2018-year-old%20adolescents%20who%20participated%20in%20the%20LIFE%20Child%20study.%20Psychosocial%20information%20%28socioeconomic%20status%20%28SES%29%20based%20on%20parents%5Cu2019%20education%2C%20occupation%20and%20household%20income%2C%20Strengths%20and%20Difficulties%20Questionnaire%20%28SDQ%29%2C%20health-related%20quality%20of%20life%29%20and%20physical%20activity%20behavior%20were%20obtained.%20Nutritional%20status%20was%20classified%20based%20on%20age-%20and%20sex-adjusted%20body%20mass%20index%20into%20underweight%2C%20overweight%2C%20normal%20weight%20and%20obese.%20Clinical%20dental%20examinations%20were%20performed%20and%20scored%20with%20respect%20to%20caries%20experience%20%28CE%29%2C%20oral%20hygiene%20%28OH%29%2C%20and%20periodontal%20status%20%28periodontal%20health%20score%3A%20PERIO-S%29.%20Age-adjusted%20regression%20analysis%20under%20the%20assumption%20of%20a%20double%20Poisson%20distribution%20was%20performed%20with%20and%20without%20adjusting%20for%20SES%20%28%5Cu03b1%20%3D%205%25%29.%20A%20total%20of%201158%20study%20participants%20%28590%20girls%2C%20568%20boys%3B%20mean%20age%2013.2%20%5Cu00b1%202.3%20years%29%20were%20included%20%2817.2%25%20were%20classified%20as%20obese%29.%20CE%20was%2020%25%20higher%20for%20moderate%20and%2060%25%20higher%20for%20low%20SES%20compared%20to%20high%20SES%20%28p%20%3C%200.05%29.%20PERIO-S%20was%2010%25%20higher%20for%20moderate%20and%2030%25%20higher%20for%20low%20compared%20to%20high%20SES%20%28p%20%3C%200.05%29.%20Poor%20OH%20was%20associated%20with%20higher%20CE%20%28Ratio%20R%20%3D%202.3%2C%20p%20%3C%200.0001%29%20and%20PERIO-S%20%28R%20%3D%203.1%2C%20p%20%3C%200.0001%29.%20Physical%20activity%20in%20a%20sports%20club%20was%20associated%20with%20lower%20CE-S%20and%20PERIO-S%20%28R%20%3D%200.85%2C%20p%20%3C%200.001%29.%20Obesity%20was%20associated%20with%20increased%20CE%20%28R%20%3D%201.3%2C%20p%20%3C%200.001%29%20compared%20to%20normal%20weight.%20For%20low%20but%20not%20high%20SES%2C%20more%20reported%20difficulties%20were%20associated%20with%20higher%20CE.%20In%20conclusion%2C%20low%20SES%2C%20poor%20OH%2C%20and%20obesity%20are%20associated%20with%20unfavorable%20oral%20health%20conditions%2C%20whereas%20physical%20activity%20and%20high%20SES%20are%20potentially%20protective.%22%2C%22date%22%3A%222022%5C%2F1%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.3390%5C%2Fijerph19052905%22%2C%22ISSN%22%3A%221660-4601%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.mdpi.com%5C%2F1660-4601%5C%2F19%5C%2F5%5C%2F2905%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-24T11%3A21%3A50Z%22%7D%7D%2C%7B%22key%22%3A%226AVE9W3V%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Vogel%20et%20al.%22%2C%22parsedDate%22%3A%222021-03%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EVogel%2C%20Mandy%2C%20Christof%20Meigen%2C%20Carolin%20Sobek%2C%20Peggy%20Ober%2C%20Ulrike%20Igel%2C%20Antje%20K%26%23xF6%3Brner%2C%20Wieland%20Kiess%2C%20and%20Tanja%20Poulain.%20%26%23x201C%3BWell-Being%20and%20Covid-19-Related%20Worries%20of%20German%20Children%20and%20Adolescents%3A%20A%20Longitudinal%20Study%20from%20Pre-Covid%20to%20the%20End%20of%20Lockdown%20in%20Spring%202020.%26%23x201D%3B%20%3Ci%3EJCPP%20Advances%3C%5C%2Fi%3E%201%2C%20no.%201%20%28March%202021%29%3A%20e12004.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fjcv2.12004%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fjcv2.12004%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Well-Being%20and%20Covid-19-Related%20Worries%20of%20German%20Children%20and%20Adolescents%3A%20A%20Longitudinal%20Study%20from%20Pre-Covid%20to%20the%20End%20of%20Lockdown%20in%20Spring%202020%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christof%22%2C%22lastName%22%3A%22Meigen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Carolin%22%2C%22lastName%22%3A%22Sobek%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Peggy%22%2C%22lastName%22%3A%22Ober%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ulrike%22%2C%22lastName%22%3A%22Igel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%5D%2C%22abstractNote%22%3A%22Background%20There%20is%20concern%20that%20pandemic%20measures%20put%20a%20strain%20on%20the%20health%20and%20well-being%20of%20children.%20We%20investigated%20the%20effects%20of%20the%20COVID-19%20pandemic%2C%20the%20lockdown%2C%20and%20social%20distancing%20on%20the%20well-being%2C%20media%20use%2C%20and%20emotions%20of%20children%20and%20adolescents%20between%209%20and%2018%20years.%20Methods%20We%20used%20linear%20and%20proportional%20odds%20logistic%20regression%20correcting%20for%20age%2C%20sex%2C%20and%20socioeconomic%20status%20%28SES%29%20and%20to%20compare%20media%20use%2C%20peers%5C%2Fsocial%20support%2C%20physical%2C%20and%20psychological%20well-being%20between%202019%20%28pre-COVID%20baseline%29%20and%20two%20time%20points%20shortly%20after%20the%20start%20of%20the%20lockdown%20%28last%20week%20of%20March%20and%20April%202020%2C%20respectively%29%20in%20391%209%5Cu201319-year-old%20healthy%20children%20and%20adolescents%20of%20the%20LIFE%20Child%20cohort.%20COVID-19-related%20feelings%20and%20their%20relationship%20to%20age%2C%20sex%2C%20and%20SES%20were%20assessed%20at%20two%20time%20points%20during%20lockdown.%20Results%20We%20found%20significantly%20lower%20scores%20in%20physical%20and%20psychological%20well-being%20during%20lockdown%20compared%20to%20baseline.%20The%20effect%20was%20significantly%20stronger%20in%20children%20with%20medium%5C%2Flow%20SES.%20Perceived%20social%20support%20scores%20were%20also%20significantly%20lower%20during%20the%20lockdown.%20The%20percentage%20of%20children%20who%20had%20no%20contact%20with%20their%20peers%20%28in-person%20or%20online%29%20increased%20from%203%25%20pre-COVID%20to%2014%25%20and%2013%25%20in%20April%20and%20March%202020%2C%20respectively.%20About%2080%25%20of%20the%20children%20missed%20in-person%20contacts%20with%20friends.%20Most%20of%20the%20children%20worried%20more%20about%20the%20health%20of%20their%20families%20than%20their%20own.%20Sixty%20percent%20worried%20about%20the%20international%20situation%20at%20least%20moderately%2C%20whereas%20only%2020%25%20were%20afraid%20of%20COVID-19%20itself.%20The%20percentage%20of%20children%20who%20believed%20it%20would%20never%20be%20as%20before%20COVID-19%20rose%20from%207.4%25%20at%20the%20beginning%20lockdown%20end%20of%20March%20to%2016.2%25%20a%20month%20later.%20In%20contrast%2C%20all%20other%20COVID-19-related%20worries%2C%20showed%20a%20%28nonsignificant%29%20decline%20during%20the%20same%20period.%20Conclusion%20Our%20study%20supports%20the%20notion%20that%20pandemic%20measures%20have%20to%20be%20balanced%20against%20adverse%20public%20health%20effects.%20Especially%20vulnerable%20groups%20have%20to%20be%20protected.%22%2C%22date%22%3A%222021-03%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1111%5C%2Fjcv2.12004%22%2C%22ISSN%22%3A%222692-9384%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Facamh.onlinelibrary.wiley.com%5C%2Fdoi%5C%2Fabs%5C%2F10.1111%5C%2Fjcv2.12004%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-24T13%3A37%3A39Z%22%7D%7D%2C%7B%22key%22%3A%226VMFZRL2%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Kreusler%20et%20al.%22%2C%22parsedDate%22%3A%222021-02%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EKreusler%2C%20Paulina%2C%20Mandy%20Vogel%2C%20Anja%20Willenberg%2C%20Ronny%20Baber%2C%20Yvonne%20Dietz%2C%20Antje%20K%26%23xF6%3Brner%2C%20Uta%20Ceglarek%2C%20and%20Wieland%20Kiess.%20%26%23x201C%3BFolate%20and%20Cobalamin%20Serum%20Levels%20in%20Healthy%20Children%20and%20Adolescents%20and%20Their%20Association%20with%20Age%2C%20Sex%2C%20Bmi%20and%20Socioeconomic%20Status.%26%23x201D%3B%20%3Ci%3ENutrients%3C%5C%2Fi%3E%2013%2C%20no.%202%20%28February%202021%29.%20%3Ca%20class%3D%27zp-ItemURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Fnu13020546%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Fnu13020546%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Folate%20and%20Cobalamin%20Serum%20Levels%20in%20Healthy%20Children%20and%20Adolescents%20and%20Their%20Association%20with%20Age%2C%20Sex%2C%20Bmi%20and%20Socioeconomic%20Status%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Paulina%22%2C%22lastName%22%3A%22Kreusler%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anja%22%2C%22lastName%22%3A%22Willenberg%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ronny%22%2C%22lastName%22%3A%22Baber%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Yvonne%22%2C%22lastName%22%3A%22Dietz%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Uta%22%2C%22lastName%22%3A%22Ceglarek%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%5D%2C%22abstractNote%22%3A%22This%20study%20proposes%20age-%20and%20sex-specific%20percentiles%20for%20serum%20cobalamin%20and%20folate%2C%20and%20analyzes%20the%20effects%20of%20sex%2C%20age%2C%20body%20mass%20index%20%28BMI%29%2C%20and%20socioeconomic%20status%20%28SES%29%20on%20cobalamin%20and%20folate%20concentrations%20in%20healthy%20children%20and%20adolescents.%20In%20total%2C%204478%20serum%20samples%20provided%20by%20healthy%20participants%20%282%20months-18.0%20years%29%20in%20the%20LIFE%20%28Leipzig%20Research%20Centre%20for%20Civilization%20Diseases%29%20Child%20population-based%20cohort%20study%20between%202011%20and%202015%20were%20analyzed%20by%20electrochemiluminescence%20immunoassay%20%28ECLIA%29.%20Continuous%20age-and%20sex-related%20percentiles%20%282.5th%2C%2010th%2C%2050th%2C%2090th%2C%2097.5th%29%20were%20estimated%2C%20applying%20Cole%27s%20LMS%20method.%20In%20both%20sexes%2C%20folate%20concentrations%20decreased%20continuously%20with%20age%2C%20whereas%20cobalamin%20concentration%20peaked%20between%20three%20and%20seven%20years%20of%20age%20and%20declined%20thereafter.%20Female%20sex%20was%20associated%20with%20higher%20concentrations%20of%20both%20vitamins%20in%2013-%20to%2018-year-olds%20and%20with%20higher%20folate%20levels%20in%20one-%20to%20five-year-olds.%20BMI%20was%20inversely%20correlated%20with%20concentrations%20of%20both%20vitamins%2C%20whilst%20SES%20positively%20affected%20folate%20but%20not%20cobalamin%20concentrations.%20To%20conclude%2C%20in%20the%20assessment%20of%20cobalamin%20and%20folate%20status%2C%20the%20age-%20and%20sex-dependent%20dynamic%20of%20the%20respective%20serum%20concentrations%20must%20be%20considered.%20While%20BMI%20is%20a%20determinant%20of%20both%20vitamin%20concentrations%2C%20SES%20is%20only%20associated%20with%20folate%20concentrations.%22%2C%22date%22%3A%222021-02%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.3390%5C%2Fnu13020546%22%2C%22ISSN%22%3A%222072-6643%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Fnu13020546%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222024-04-10T08%3A01%3A32Z%22%7D%7D%2C%7B%22key%22%3A%22GMJ7Y6B3%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Lewien%20et%20al.%22%2C%22parsedDate%22%3A%222021-02%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3ELewien%2C%20Christiane%2C%20Jon%20Genuneit%2C%20Christof%20Meigen%2C%20Wieland%20Kiess%2C%20and%20Tanja%20Poulain.%20%26%23x201C%3BSleep-Related%20Difficulties%20in%20Healthy%20Children%20and%20Adolescents.%26%23x201D%3B%20%3Ci%3EBMC%20Pediatrics%3C%5C%2Fi%3E%2021%2C%20no.%201%20%28February%202021%29%3A%2082.%20%3Ca%20class%3D%27zp-ItemURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs12887-021-02529-y%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs12887-021-02529-y%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Sleep-Related%20Difficulties%20in%20Healthy%20Children%20and%20Adolescents%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christiane%22%2C%22lastName%22%3A%22Lewien%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jon%22%2C%22lastName%22%3A%22Genuneit%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christof%22%2C%22lastName%22%3A%22Meigen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%5D%2C%22abstractNote%22%3A%22BACKGROUND%3A%20As%20sleep-related%20difficulties%20are%20a%20growing%20public%20health%20concern%2C%20it%20is%20important%20to%20gain%20an%20overview%20of%20the%20specific%20difficulty%20areas%20of%20the%20most%20vulnerable%20individuals%3A%20children.%20The%20current%20descriptive%20study%20presents%20the%20prevalence%20of%20sleep-related%20difficulties%20in%20two%20large%20samples%20of%20healthy%20children%20and%20adolescents%20and%20outlines%20the%20effects%20of%20age%2C%20gender%2C%20and%20socioeconomic%20status%20%28SES%29%20on%20various%20sleep-related%20difficulties.%5CnMETHODS%3A%20Participants%20were%20855%204-9%20year-old%20children%20%28child%20sample%29%20and%201%2C047%2010-17%20year-old%20adolescents%20%28adolescent%20sample%29%20participating%202011-2015%5Cu00a0in%20the%20LIFE%20Child%20study%2C%20a%20population-based%20cohort%20study%20in%20Germany.%20Parents%20of%20the%20child%20participants%20completed%20the%20Children%27s%20Sleep%20Habits%20Questionnaire%20%28CSHQ%29%2C%20whereas%20adolescents%20self-administered%20the%20Sleep%20Self%20Report%20%28SSR%29.%20Familial%20SES%20was%20determined%20by%20a%20composite%20score%20considering%20parental%20education%2C%20occupational%20status%2C%20and%20income.%20Multiple%20regression%20analyses%20were%20carried%20out%20to%20address%20the%20research%20question.%5CnRESULTS%3A%20Among%204-9%20year-old%20children%2C%20the%20mean%20bedtime%20was%20reported%20to%20be%208%20p.m.%2C%20the%20mean%20wake-up%20time%207%20a.m.%2C%20and%20sleep%20duration%20decreased%20by%2014%5Cu00a0min%5C%2Fyear%20of%20age.%2022.6%5Cu2009%25%20of%20the%20children%20and%2020.0%5Cu2009%25%20of%20the%20adolescents%20showed%20problematic%20amounts%20of%20sleep-related%20difficulties.%20In%20the%20child%20sample%2C%20bedtime%20resistance%2C%20sleep%20onset%20delay%2C%20sleep-related%20anxiety%2C%20night%20waking%2C%20and%20parasomnia%20were%20more%20frequent%20in%20younger%20than%20older%20children.%20In%20the%20adolescent%20sample%2C%20difficulties%20at%20bedtime%20were%20more%20frequent%20among%20the%20younger%20adolescents%2C%20whereas%20daytime%20sleepiness%20was%20more%20prominent%20in%20the%20older%20than%20the%20younger%20adolescents.%20Considering%20gender%20differences%2C%20sleep-related%20difficulties%20were%20more%20frequent%20among%20boys%20in%20the%20child%20sample%20and%20among%20girls%20in%20the%20adolescent%20sample.%20Lower%20SES%20was%20associated%20with%20increased%20sleep-related%20difficulties%20in%20the%20adolescent%2C%20but%20not%20the%20child%20sample.%5CnCONCLUSIONS%3A%20The%20present%20results%20report%20sleep-related%20difficulties%20throughout%20both%20childhood%20and%20adolescence.%20Gender%20differences%20can%20already%20be%20observed%20in%20early%20childhood%2C%20while%20effects%20of%20SES%20emerge%20only%20later%20in%20adolescence.%20The%20awareness%20for%20this%20circumstance%20is%20of%20great%20importance%20for%20pediatric%20clinicians%20who%20ought%20to%20early%20identify%20sleep-related%20difficulties%20in%20particularly%20vulnerable%20individuals.%22%2C%22date%22%3A%222021-02%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1186%5C%2Fs12887-021-02529-y%22%2C%22ISSN%22%3A%221471-2431%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs12887-021-02529-y%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-07T07%3A01%3A40Z%22%7D%7D%2C%7B%22key%22%3A%22SDKMQ3W6%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22M%5Cu00f6ller%20et%20al.%22%2C%22parsedDate%22%3A%222021%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EM%26%23xF6%3Bller%2C%20Siegfried%2C%20Tanja%20Poulain%2C%20Antje%20K%26%23xF6%3Brner%2C%20Christof%20Meigen%2C%20Anne%20Jurkutat%2C%20Mandy%20Vogel%2C%20Sven%20Wessela%2C%20Andreas%20Hiemisch%2C%20Nico%20Grafe%2C%20and%20Wieland%20Kiess.%20%26%23x201C%3BMotor%20Skills%20in%20Relation%20to%20Body-Mass%20Index%2C%20Physical%20Activity%2C%20Tv-Watching%2C%20and%20Socioeconomic%20Status%20in%20German%20Four-to-17-Year-Old%20Children.%26%23x201D%3B%20%3Ci%3EPloS%20One%3C%5C%2Fi%3E%2016%2C%20no.%205%20%282021%29%3A%20e0251738.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1371%5C%2Fjournal.pone.0251738%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1371%5C%2Fjournal.pone.0251738%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Motor%20Skills%20in%20Relation%20to%20Body-Mass%20Index%2C%20Physical%20Activity%2C%20Tv-Watching%2C%20and%20Socioeconomic%20Status%20in%20German%20Four-to-17-Year-Old%20Children%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Siegfried%22%2C%22lastName%22%3A%22M%5Cu00f6ller%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christof%22%2C%22lastName%22%3A%22Meigen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anne%22%2C%22lastName%22%3A%22Jurkutat%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Sven%22%2C%22lastName%22%3A%22Wessela%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andreas%22%2C%22lastName%22%3A%22Hiemisch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Nico%22%2C%22lastName%22%3A%22Grafe%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%5D%2C%22abstractNote%22%3A%22BACKGROUND%3A%20The%20present%20study%20describes%20motor%20skills%20in%20a%20large%20sample%20of%20German%20children%20and%20adolescents%20and%20investigates%20associations%20with%20age%2C%20gender%2C%20body-mass%20index%2C%20physical%20activity%2C%20television%20time%2C%20and%20socioeconomic%20status.%5CnMETHODS%3A%202%2C106%20children%20%281076%20boys%2C%201030%20girls%29%20aged%204%20to%2017%20years%20performed%20five%20different%20motor%20tests%20for%20strength%20%28pushups%2C%20standing%20long%20jump%29%2C%20coordination%20%28backward%20balancing%2C%20jumping%20side-to-side%29%20and%20flexibility%20%28forward%20bend%29%20within%20the%20framework%20of%20the%20LIFE%20Child%20study%20%28Leipzig%2C%20Germany%29.%20Anthropometric%20parameters%20were%20assessed%20through%20standardized%20measurement.%20Data%20on%20physical%20activity%2C%20television%20time%2C%20and%20socioeconomic%20status%20were%20collected%20via%20questionnaires.%20Linear%20regression%20analyses%20were%20applied%20to%20assess%20relations.%5CnRESULTS%3A%20Strength%20and%20coordination%20performance%20were%20higher%20in%20older%20than%20in%20younger%20children.%20While%20boys%20showed%20a%20higher%20performance%20in%20strengths%20tests%20than%20girls%2C%20girls%20performed%20better%20in%20flexibility%20and%20coordination%20during%20precision%20tasks%20%28backward%20balancing%29.%20In%20terms%20of%20coordination%20under%20time%20constraint%20%28jumping%20side-to-side%29%2C%20both%20genders%20produced%20similar%20results.%20Lower%20body-mass%20index%2C%20higher%20physical%20activity%2C%20and%20higher%20socioeconomic%20status%20were%20significantly%20related%20to%20better%20motor%20skills.%20Longer%20television%20times%20were%20significantly%20associated%20with%20lower%20performance%20in%20long%20jump.%5CnCONCLUSIONS%3A%20The%20present%20findings%20are%20similar%20to%20data%20collected%20at%20the%20beginning%20of%20the%20century%2C%20indicating%20that%20motor%20skills%20have%20hardly%20changed%20in%20recent%20years.%20The%20findings%20furthermore%20suggest%20that%20children%20from%20lower%20social%20strata%2C%20children%20with%20higher%20body%20weight%2C%20and%20children%20who%20move%20little%20have%20a%20higher%20risk%20of%20developing%20insufficient%20motor%20skills%20and%20should%20therefore%20be%20given%20special%20support.%22%2C%22date%22%3A%222021%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1371%5C%2Fjournal.pone.0251738%22%2C%22ISSN%22%3A%221932-6203%22%2C%22url%22%3A%22https%3Adoi.org%5C%2F10.1371%5C%2Fjournal.pone.0251738%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-24T10%3A01%3A28Z%22%7D%7D%2C%7B%22key%22%3A%222F7NMUCQ%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Oelkers%20et%20al.%22%2C%22parsedDate%22%3A%222020%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EOelkers%2C%20Lea%2C%20Mandy%20Vogel%2C%20Agnes%20Kalenda%2C%20Hans%20Christian%20Surup%2C%20Antje%20K%26%23xF6%3Brner%2C%20J%26%23xFC%3Brgen%20Kratzsch%2C%20and%20Wieland%20Kiess.%20%26%23x201C%3BSocioeconomic%20Status%20Is%20Related%20to%20Pubertal%20Development%20in%20a%20German%20Cohort.%26%23x201D%3B%20%3Ci%3EHormone%20Research%20in%20Paediatrics%3C%5C%2Fi%3E%2093%2C%20no.%209%26%23×2013%3B10%20%282020%29%3A%20548%26%23×2013%3B57.%20%3Ca%20class%3D%27zp-ItemURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1159%5C%2F000513787%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1159%5C%2F000513787%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Socioeconomic%20Status%20Is%20Related%20to%20Pubertal%20Development%20in%20a%20German%20Cohort%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Lea%22%2C%22lastName%22%3A%22Oelkers%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Agnes%22%2C%22lastName%22%3A%22Kalenda%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Hans%20Christian%22%2C%22lastName%22%3A%22Surup%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J%5Cu00fcrgen%22%2C%22lastName%22%3A%22Kratzsch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%5D%2C%22abstractNote%22%3A%22INTRODUCTION%3A%20Current%20health%20literature%20suggests%20that%20there%20has%20been%20a%20decline%20in%20the%20age%20of%20pubertal%20onset%20and%20that%20pubertal%20onset%5C%2Fduration%20of%20puberty%20may%2C%20besides%20weight%20status%2C%20be%20influenced%20by%20socioeconomic%20context.%5CnOBJECTIVE%3A%20The%20goal%20of%20this%20study%20was%20to%20determine%20whether%20pubertal%20onset%5C%2Fduration%20and%20puberty-triggering%20hormones%20luteinizing%20hormone%20%28LH%29%20and%20follicle-stimulating%20hormone%20%28FSH%29%20vary%20according%20to%20socioeconomic%20status%20%28SES%29.%20Moreover%2C%20we%20aimed%20to%20propose%20cutoff%20values%20of%20serum%20LH%20and%20FSH%20for%20predicting%20gonadarche%20in%20boys.%5CnMETHODS%3A%202%2C657%20apparently%20healthy%20children%20and%20adolescents%20between%205.5%20and%2018%20years%20from%20the%20area%20of%20Leipzig%20were%20recruited%20from%20the%20LIFE%20Child%20study.%20Age%20at%20pubertal%20onset%5C%2Fend%20of%20puberty%20was%20given%20in%20738%5C%2F573%20children%2C%20respectively.%20Anthropometric%20parameters%20of%20puberty%2C%20blood%20measurements%20of%20LH%20and%20FSH%2C%20and%20questionnaires%20assessing%20SES%20were%20evaluated.%5CnRESULTS%3A%20Lower%20SES%20was%20associated%20with%20earlier%20thelarche%20and%20longer%20duration%20of%20puberty%20in%20overweight%5C%2Fobese%20girls%2C%20whereas%20age%20of%20menarche%20was%20not%20affected.%20In%20boys%20with%20low%20SES%2C%20a%20trend%20versus%20earlier%20puberty%20onset%20can%20be%20seen.%20Lower%20SES%20was%20significantly%20associated%20with%20boys%27%20age%20at%20mutation.%20No%20significant%20differences%20in%20boys%27%20and%20girls%27%20serum%20levels%20of%20LH%20and%20FSH%20during%20puberty%20according%20to%20SES%20were%20observed.%20Serum%20LH%20levels%20of%200.56%20IU%5C%2FL%20and%20serum%20FSH%20levels%20of%201.74%20IU%5C%2FL%20showed%20the%20best%20prediction%20of%20gonadarche%20in%20boys.%5CnCONCLUSION%3A%20Puberty%20onset%5C%2Fduration%20and%20boys%27%20age%20at%20mutation%20is%20affected%20by%20SES.%20The%20proposed%20cutoff%20levels%20for%20serum%20LH%20and%20FSH%20could%20provide%20a%20serological%20tool%20to%20determine%20gonadarche%20in%20boys.%22%2C%22date%22%3A%222020%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1159%5C%2F000513787%22%2C%22ISSN%22%3A%221663-2826%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1159%5C%2F000513787%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-07T07%3A01%3A36Z%22%7D%7D%2C%7B%22key%22%3A%22TC3D9JMH%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Poulain%20et%20al.%22%2C%22parsedDate%22%3A%222019-12%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EPoulain%2C%20Tanja%2C%20Mandy%20Vogel%2C%20and%20Wieland%20Kiess.%20%26%23x201C%3BReview%20on%20the%20Role%20of%20Socioeconomic%20Status%20in%20Child%20Health%20and%20Development.%26%23x201D%3B%20%3Ci%3ECurrent%20Opinion%20in%20Pediatrics%3C%5C%2Fi%3E%2032%2C%20no.%202%20%28December%202019%29%3A%20308%26%23×2013%3B14.%20%3Ca%20class%3D%27zp-ItemURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1097%5C%2FMOP.0000000000000876.%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1097%5C%2FMOP.0000000000000876.%3C%5C%2Fa%3E%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Review%20on%20the%20Role%20of%20Socioeconomic%20Status%20in%20Child%20Health%20and%20Development%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%5D%2C%22abstractNote%22%3A%22PURPOSE%20OF%20REVIEW%3A%20This%20review%20presents%20findings%20from%20recent%20studies%20investigating%20the%20role%20of%20socioeconomic%20status%20%28SES%29%20in%20child%20development.%20Studies%20on%20associations%20between%20SES%20and%20different%20parameters%20of%20physical%20and%20psychological%20health%2C%20on%20interventions%20and%20possible%20resilience%20factors%20are%20reviewed.%5CnRECENT%20FINDINGS%3A%20Several%20cross-sectional%20and%20longitudinal%20studies%20demonstrate%20social%20disparities%20in%20child%20behavior%20and%20health.%20They%20underline%20the%20detrimental%20effects%20of%20low%20SES%20on%20child%20development.%20Some%20studies%20also%20highlight%20the%20potentially%20adverse%20effects%20of%20early%20diseases%20or%20vulnerabilities%20on%20later%20career%20and%20social%20position.%20Whereas%20most%20studies%20applied%20parent-based%20measures%20of%20SES%2C%20some%20studies%20emphasize%20the%20significance%20of%20child-based%20%28e.g.%20perceived%20social%20position%29%20and%20area-level%20indicators%20of%20SES%20%28e.g.%20area%20deprivation%29.%20With%20respect%20to%20intervention%2C%20study%20findings%20suggest%20positive%20effects%20of%20programs%20aiming%20to%20improve%20specific%20neighborhood%20characteristics%20and%20psychosocial%20functioning%20of%20individuals.%5CnSUMMARY%3A%20The%20relation%20between%20SES%20and%20health%20is%20bidirectional%20and%20stable%2C%20and%20the%20effects%20of%20interventions%20aiming%20at%20changing%20behaviors%20of%20children%20and%20families%20with%20low%20SES%20are%20small.%20There%20is%20a%20need%20for%20further%20center-based%20and%20area-level%20interventions%20and%20studies%20evaluating%20the%20effects%20of%20these%20interventions.%22%2C%22date%22%3A%22Dec%2C%202019%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1097%5C%2FMOP.0000000000000876%22%2C%22ISSN%22%3A%221531-698X%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1097%5C%2FMOP.0000000000000876.%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-07T07%3A01%3A31Z%22%7D%7D%2C%7B%22key%22%3A%22RY5VI9KJ%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Elger%20et%20al.%22%2C%22parsedDate%22%3A%222019-05%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EElger%2C%20Wieland%2C%20Wieland%20Kiess%2C%20Antje%20K%26%23xF6%3Brner%2C%20Annett%20Schrock%2C%20Mandy%20Vogel%2C%20and%20Christian%20Hirsch.%20%26%23x201C%3BInfluence%20of%20Overweight%5C%2FObesity%2C%20Socioeconomic%20Status%2C%20and%20Oral%20Hygiene%20on%20Caries%20in%20Primary%20Dentition.%26%23x201D%3B%20%3Ci%3EJournal%20of%20Investigative%20and%20Clinical%20Dentistry%3C%5C%2Fi%3E%2010%2C%20no.%202%20%28May%202019%29%3A%20e12394.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fjicd.12394%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fjicd.12394%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Influence%20of%20Overweight%5C%2FObesity%2C%20Socioeconomic%20Status%2C%20and%20Oral%20Hygiene%20on%20Caries%20in%20Primary%20Dentition%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Elger%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Annett%22%2C%22lastName%22%3A%22Schrock%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christian%22%2C%22lastName%22%3A%22Hirsch%22%7D%5D%2C%22abstractNote%22%3A%22AIM%3A%20The%20aim%20of%20the%20present%20study%20was%20to%20investigate%20possible%20influences%20of%20overweight%20%28OW%29%5C%2Fobesity%20on%20caries%20in%20primary%20dentition.%20Socioeconomic%20status%20%28SES%29%20and%20quality%20of%20oral%20hygiene%20were%20also%20considered.%5CnMETHODS%3A%20In%20the%20present%20study%2C%201628%20children%20between%20the%20ages%20of%206%5Cu00a0months%20and%209%5Cu00a0years%20were%20included.%20In%20addition%20to%20dental%20examinations%20regarding%20the%20decayed%2C%20missing%2C%20filled%20teeth%20%28dmft%29%20index%20in%20primary%20dentition%20and%20the%20evaluation%20of%20oral%20hygiene%2C%20the%20body%20mass%20index%20standard%20deviation%20score%20%28BMI%20SDS%29%20was%20determined%2C%20and%20SES%20was%20recorded.%5CnRESULTS%3A%20The%20presence%20of%20OW%5C%2Fobesity%20was%20associated%20with%20higher%20caries%20prevalence%20%28P%5Cu00a0%3C%5Cu00a00.001%29.%20A%20lower%20SES%20and%20non-optimal%20oral%20hygiene%20were%20also%20associated%20with%20increased%20dmft.%20The%20Poisson%20regression%20also%20showed%20a%20significantly%20higher%20risk%20in%20the%20combination%20of%20a%20high%20SES%20and%20OW%5C%2Fobesity%20%28%5Cu03b2low-high%20%5Cu00a0%3D%5Cu00a00.21%2C%20P%5Cu00a0%3D%5Cu00a00.01%29.%20The%20increase%20was%20evident%20in%20both%20good%20and%20poor%20oral%20hygiene.%20In%20contrast%2C%20there%20was%20no%20difference%20between%20the%20lower%20and%20middle%20social%20strata%20%28%5Cu03b2low-medium%20%5Cu00a0%3D%5Cu00a00.03%2C%20P%5Cu00a0%3D%5Cu00a00.6%29.%20With%20increasing%20age%2C%20the%20BMI%20influence%20decreased%20%28%5Cu03b2age%3ABMISDS%20%5Cu00a0%3D%5Cu00a0-0.06%2C%20P%5Cu00a0%3C%5Cu00a00.001%29.%5CnCONCLUSIONS%3A%20BMI%2C%20oral%20hygiene%2C%20and%20SES%20are%20important%20factors%20in%20caries%20prevalence.%20In%20the%20highest%20social%20class%2C%20however%2C%20increased%20body%20weight%20has%20an%20adverse%20effect%20regardless%20of%20oral%20hygiene.%22%2C%22date%22%3A%22May%202019%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1111%5C%2Fjicd.12394%22%2C%22ISSN%22%3A%222041-1626%22%2C%22url%22%3A%22http%3A%5C%2F%5C%2Forgid.org%5C%2F10.1111%5C%2Fjicd.12394%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-07T07%3A01%3A49Z%22%7D%7D%2C%7B%22key%22%3A%22F4Z2WE55%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Buzek%20et%20al.%22%2C%22parsedDate%22%3A%222019-04-01%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EBuzek%2C%20Theresa%2C%20Tanja%20Poulain%2C%20Mandy%20Vogel%2C%20Christoph%20Engel%2C%20Sarah%20Bussler%2C%20Antje%20K%26%23xF6%3Brner%2C%20Andreas%20Hiemisch%2C%20and%20Wieland%20Kiess.%20%26%23x201C%3BRelations%20Between%20Sleep%20Duration%20with%20Overweight%20and%20Academic%20Stress%26%23×2014%3BJust%20a%20Matter%20of%20the%20Socioeconomic%20Status%3F%26%23x201D%3B%20%3Ci%3ESleep%20Health%3C%5C%2Fi%3E%205%2C%20no.%202%20%28April%201%2C%202019%29%3A%20208%26%23×2013%3B15.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.sleh.2018.12.004%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.sleh.2018.12.004%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Relations%20Between%20Sleep%20Duration%20with%20Overweight%20and%20Academic%20Stress%5Cu2014Just%20a%20Matter%20of%20the%20Socioeconomic%20Status%3F%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Theresa%22%2C%22lastName%22%3A%22Buzek%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christoph%22%2C%22lastName%22%3A%22Engel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Sarah%22%2C%22lastName%22%3A%22Bussler%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andreas%22%2C%22lastName%22%3A%22Hiemisch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%5D%2C%22abstractNote%22%3A%22Objectives%5CnShorter%20sleep%20duration%20in%20childhood%20has%20already%20been%20associated%20with%20health-related%20and%20psychological%20factors%2C%20such%20as%20overweight%5C%2Fobesity%20or%20stress.%20This%20study%20investigates%20associations%20of%20sleep%20duration%20with%20overweight%5C%2Fobesity%20and%20stress%20related%20to%20academic%20success%20in%20school%20%28%5Cu201cacademic%20stress%5Cu201d%29%20in%20dependence%20on%20children%5Cu2019s%20socioeconomic%20status.%5CnDesign%5CnCross-sectional.%5CnSetting%5CnLIFE%20Child%20Study%2C%20a%20study%20investigating%20child%20development%20from%20pregnancy%20to%20adulthood.%5CnParticipants%5CnA%20total%20of%201537%20%282325%20observations%29%201-%20to%2014-year-old%20children%20were%20considered.%20Analyses%20on%20academic%20stress%20were%20performed%20in%20a%20subgroup%20of%20450%20school-aged%20children%20%28631%20observations%29.%5CnMeasurements%5CnAssociations%20between%20sleep%20duration%20and%20overweight%5C%2Fobesity%20as%20well%20as%20academic%20stress%20were%20analyzed%20using%20linear%20mixed-effect%20regression%20models%20controlling%20for%20multiple%20visits.%20Importantly%2C%20all%20associations%20were%20checked%20for%20interactions%20with%20families%5Cu2019%20socioeconomic%20status.%5CnResults%5CnThe%20analyses%20revealed%20negative%20associations%20between%20sleep%20duration%20and%20overweight%5C%2Fobesity%20as%20well%20as%20academic%20stress%2C%20which%2C%20however%2C%20were%20only%20observable%20in%20children%20from%20families%20with%20a%20low%20socioeconomic%20status.%20The%20associations%20were%20consistent%20across%20all%20ages.%5CnConclusions%5CnThe%20findings%20suggest%20that%20children%20from%20families%20with%20a%20low%20socioeconomic%20status%20have%20a%20higher%20susceptibility%20for%20risk%20factors%20promoting%20sleep%20deficiency%2C%20overweight%2C%20or%20academic%20stress%2C%20for%20example%2C%20unhealthy%20food%20intake%2C%20high%20media%20consumption%2C%20or%20the%20loss%20of%20coping%20strategies%20for%20academic%20stress%20at%20school.%22%2C%22date%22%3A%22April%201%2C%202019%22%2C%22language%22%3A%22%22%2C%22DOI%22%3A%2210.1016%5C%2Fj.sleh.2018.12.004%22%2C%22ISSN%22%3A%222352-7218%22%2C%22url%22%3A%22http%3A%5C%2F%5C%2Fwww.sciencedirect.com%5C%2Fscience%5C%2Farticle%5C%2Fpii%5C%2FS235272181830247X%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-23T10%3A56%3A31Z%22%7D%7D%2C%7B%22key%22%3A%22LGP5DMF7%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Haas%20et%20al.%22%2C%22parsedDate%22%3A%222019-03%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EHaas%2C%20Myriam%2C%20Andreas%20Hiemisch%2C%20Mandy%20Vogel%2C%20Oleg%20Wagner%2C%20Wieland%20Kiess%2C%20and%20Tanja%20Poulain.%20%26%23x201C%3BSensation%20Seeking%20in%203-%20to%206-Year-Old%20Children%3A%20Associations%20with%20Socio-Demographic%20Parameters%20and%20Behavioural%20Difficulties.%26%23x201D%3B%20%3Ci%3EBMC%20Pediatrics%3C%5C%2Fi%3E%2019%2C%20no.%201%20%28March%202019%29%3A%2077.%20%3Ca%20class%3D%27zp-ItemURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs12887-019-1450-6%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs12887-019-1450-6%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Sensation%20Seeking%20in%203-%20to%206-Year-Old%20Children%3A%20Associations%20with%20Socio-Demographic%20Parameters%20and%20Behavioural%20Difficulties%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Myriam%22%2C%22lastName%22%3A%22Haas%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andreas%22%2C%22lastName%22%3A%22Hiemisch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Oleg%22%2C%22lastName%22%3A%22Wagner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%5D%2C%22abstractNote%22%3A%22Background%3A%20The%20present%20study%20investigates%20whether%20sensation%20seeking%20in%20pre-school-age%20children%20is%20associated%20with%20age%2C%20gender%20and%20socio-economic%20status%2C%20and%20how%20sensation%20seeking%20relates%20to%20behavioural%20difficulties.%5CnMethods%3A%20The%20study%20sample%20consisted%20of%20423%20three-%20to%20six-year-old%20children%20whose%20parents%20had%20completed%20questionnaires%20on%20the%20children%5Cu2019s%20sensation%20seeking%20%28Sensation%20Seeking%20Scale%20for%20Young%20Children%29%2C%20socio-economic%20status%2C%20and%20behavioural%20difficulties%20%28Strengths%20and%20Difficulties%20Questionnaire%29.%20Multiple%20linear%20regression%20models%20were%20applied%20to%20investigate%20associations%20between%20sensation%20seeking%20and%20age%2C%20gender%2C%20socio-economic%20status%20and%20behavioural%20difficulties.%5CnResults%3A%20Sensation%20seeking%20was%20significantly%20higher%20in%20male%20vs.%20female%20children%20but%20not%20associated%20with%20children%5Cu2019s%20socio-economic%20status.%20Furthermore%2C%20sensation%20seeking%20was%20positively%20correlated%20with%20conduct%20problems%2C%20but%20negatively%20with%20emotional%20symptoms%20and%20peer-relationship%20problems.%5CnConclusion%3A%20These%20results%20replicate%20findings%20in%20adults%20and%20strengthen%20the%20assumption%20that%20sensation%20seeking%20is%20a%20personality%20trait%20that%20is%20already%20observable%20in%20early%20childhood.%20Furthermore%2C%20our%20results%20suggest%20relationships%20between%20higher%20levels%20of%20sensation%20seeking%20and%20externalising%20behaviour%20as%20well%20as%20relationships%20between%20lower%20levels%20of%20sensation%20seeking%20and%20internalising%20behaviour.%22%2C%22date%22%3A%22March%2C%202019%22%2C%22language%22%3A%22%22%2C%22DOI%22%3A%2210.1186%5C%2Fs12887-019-1450-6%22%2C%22ISSN%22%3A%221471-2431%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs12887-019-1450-6%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-07T07%3A01%3A46Z%22%7D%7D%2C%7B%22key%22%3A%22M2Y7I8ZD%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Poulain%20et%20al.%22%2C%22parsedDate%22%3A%222019-01%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EPoulain%2C%20Tanja%2C%20Mandy%20Vogel%2C%20Carolin%20Sobek%2C%20Anja%20Hilbert%2C%20Antje%20K%26%23xF6%3Brner%2C%20and%20Wieland%20Kiess.%20%26%23x201C%3BAssociations%20Between%20Socio-Economic%20Status%20and%20Child%20Health%3A%20Findings%20of%20a%20Large%20German%20Cohort%20Study.%26%23x201D%3B%20%3Ci%3EInternational%20Journal%20of%20Environmental%20Research%20and%20Public%20Health%3C%5C%2Fi%3E%2016%2C%20no.%205%20%28January%202019%29%3A%20677.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Fijerph16050677%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Fijerph16050677%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Associations%20Between%20Socio-Economic%20Status%20and%20Child%20Health%3A%20Findings%20of%20a%20Large%20German%20Cohort%20Study%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Carolin%22%2C%22lastName%22%3A%22Sobek%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anja%22%2C%22lastName%22%3A%22Hilbert%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%5D%2C%22abstractNote%22%3A%22The%20familial%20social%20background%20of%20a%20child%20can%20significantly%20impact%20their%20behavior%20and%20health.%20We%20investigated%20associations%20between%20socio-economic%20status%20%28SES%29%20and%20health%20parameters%20and%20behaviors%20in%20German%20children%20and%20adolescents.%20Data%20were%20collected%20between%202011%20and%202018%20in%20the%20framework%20of%20the%20LIFE%20Child%20study.%20Participants%20included%202998%20children%20aged%203%26ndash%3B18%20years.%20SES%20was%20represented%20by%20an%20index%20combining%20information%20on%20parental%20education%2C%20occupation%2C%20and%20income.%20Associations%20between%20SES%20and%20health%20outcomes%20were%20estimated%20using%20linear%20and%20logistic%20regression%20analyses.%20In%20a%20moderator%20analysis%2C%20all%20associations%20were%20checked%20for%20interactions%20between%20SES%20and%20age%20or%20sex.%20A%20higher%20SES%20composite%20score%20was%20associated%20with%20better%20health%20%28lower%20body%20mass%20index%20%28%26beta%3B%20%3D%20%26minus%3B0.26%29%2C%20fewer%20behavioral%20difficulties%20%28%26beta%3B%20%3D%20%26minus%3B0.18%29%2C%20higher%20quality%20of%20life%20%28%26beta%3B%20%3D%200.21%29%2C%20fewer%20critical%20life%20events%20%28odds%20ratio%20%28OR%29%20%3D%200.93%29%3B%20all%20p%20%26lt%3B%200.05%29%20and%20a%20healthier%20lifestyle%20%28healthier%20nutrition%20%28%26beta%3B%20%3D%200.16%29%2C%20less%20excessive%20television%20use%20%28OR%20%3D%200.87%29%2C%20less%20nicotine%20consumption%20%28OR%20%3D%200.93%29%2C%20and%20more%20physical%20activity%20%28OR%20%3D%201.18%29%3B%20all%20p%20%26lt%3B%200.05%29.%20However%2C%20SES%20was%20not%20associated%20with%20alcohol%20consumption%20%28OR%20%3D%201.02%29%20or%20sleep%20problems%20%28%26beta%3B%20%3D%20%26minus%3B0.04%29.%20The%20strengths%20of%20the%20associations%20between%20SES%20and%20child%20health%20did%20not%20differ%20depending%20on%20SES%20indicator%20%28education%2C%20occupation%2C%20income%29.%20The%20associations%20between%20SES%20and%20parent-reported%20behavioral%20difficulties%20and%20physical%20activity%20were%20stronger%20in%20older%20vs.%20younger%20children.%20In%20contrast%2C%20none%20of%20the%20observed%20associations%20were%20moderated%20by%20sex.%20This%20study%20highlights%20the%20strong%20association%20between%20socio-economic%20status%20and%20child%20health%2C%20even%20in%20modern%20Western%20societies.%22%2C%22date%22%3A%22January%202019%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.3390%5C%2Fijerph16050677%22%2C%22ISSN%22%3A%22%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.mdpi.com%5C%2F1660-4601%5C%2F16%5C%2F5%5C%2F677%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-24T11%3A06%3A21Z%22%7D%7D%2C%7B%22key%22%3A%229DSFTBLA%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Herrmann%20et%20al.%22%2C%22parsedDate%22%3A%222018-03%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EHerrmann%2C%20Janine%2C%20Mandy%20Vogel%2C%20Diana%20Pietzner%2C%20Esther%20Kroll%2C%20Oleg%20Wagner%2C%20Sarah%20Schwarz%2C%20Eva%20M%26%23xFC%3Bller%2C%20Wieland%20Kiess%2C%20Matthias%20Richter%2C%20and%20Tanja%20Poulain.%20%26%23x201C%3BFactors%20Associated%20with%20the%20Emotional%20Health%20of%20Children%3A%20High%20Family%20Income%20as%20a%20Protective%20Factor.%26%23x201D%3B%20%3Ci%3EEuropean%20Child%20%26amp%3B%20Adolescent%20Psychiatry%3C%5C%2Fi%3E%2027%2C%20no.%203%20%28March%202018%29%3A%20319%26%23×2013%3B28.%20%3Ca%20class%3D%27zp-ItemURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs00787-017-1049-0%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs00787-017-1049-0%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Factors%20Associated%20with%20the%20Emotional%20Health%20of%20Children%3A%20High%20Family%20Income%20as%20a%20Protective%20Factor%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Janine%22%2C%22lastName%22%3A%22Herrmann%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Diana%22%2C%22lastName%22%3A%22Pietzner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Esther%22%2C%22lastName%22%3A%22Kroll%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Oleg%22%2C%22lastName%22%3A%22Wagner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Sarah%22%2C%22lastName%22%3A%22Schwarz%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Eva%22%2C%22lastName%22%3A%22M%5Cu00fcller%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Matthias%22%2C%22lastName%22%3A%22Richter%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%5D%2C%22abstractNote%22%3A%22Anxiety%20and%20depressive%20symptoms%20have%20adverse%20effects%20on%20children%5Cu2019s%20development.%20The%20present%20study%20investigates%20the%20associations%20of%20socioeconomic%20factors%20as%20well%20as%20maternal%20emotional%20health%20with%20children%5Cu2019s%20emotional%20health%20status.%20The%20data%20were%20collected%20between%202011%20and%202015%20in%20the%20LIFE%20Child%20study%2C%20a%20population-based%20cohort%20study%20in%20Leipzig%2C%20Germany.%20The%20emotional%20health%20status%20of%201093%20children%20%282.5%5Cu201311.9%20years%20old%29%20was%20investigated%20using%20the%20subscale%20%5Cu2018emotional%20problems%5Cu2019%20of%20the%20Strengths%20and%20Difficulties%20Questionnaire.%20Associations%20of%20maternal%20emotional%20health%2C%20family%20status%2C%20and%20socioeconomic%20status%20%28SES%29%20with%20the%20emotional%20health%20status%20of%20children%20were%20estimated%20via%20regression%20analyses.%2021.13%25%20of%20the%20participating%20children%20were%20assigned%20to%20the%20%5Cu2018risk%5Cu2019%20group%20for%20emotional%20problems.%20The%20results%20furthermore%20revealed%20that%20children%20of%20mothers%20reporting%20more%20depressive%20symptoms%2C%20children%20living%20in%20single-parent%20families%2C%20and%20children%20of%20families%20with%20lower%20SES%20scored%20higher%20in%20the%20emotional%20problems%20scale.%20When%20considering%20the%20different%20indicators%20of%20SES%20%28parental%20education%2C%20occupational%20status%2C%20and%20monthly%20net%20income%29%20separately%2C%20only%20income%20showed%20significant%20associations%20with%20children%5Cu2019s%20emotional%20health%20status.%20The%20prevalence%20of%20emotional%20problems%20in%20children%20in%20Leipzig%2C%20a%20city%20in%20East%20Germany%2C%20appears%20to%20be%20higher%20than%20the%20previously%20reported%20German%20average.%20Maternal%20depressive%20symptoms%2C%20single-parent%20families%2C%20lower%20SES%2C%20and%20especially%20lower%20income%20can%20be%20seen%20as%20risk%20factors%20for%20children%5Cu2019s%20emotional%20health.%22%2C%22date%22%3A%22March%2C%202018%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1007%5C%2Fs00787-017-1049-0%22%2C%22ISSN%22%3A%221435-165X%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs00787-017-1049-0%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-07T07%3A01%3A44Z%22%7D%7D%2C%7B%22key%22%3A%227GPF6D4S%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Rieger%20et%20al.%22%2C%22parsedDate%22%3A%222018-03%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3ERieger%2C%20Kristin%2C%20Mandy%20Vogel%2C%20Christoph%20Engel%2C%20Uta%20Ceglarek%2C%20Kristian%20Harms%2C%20Ulrike%20Wurst%2C%20Holger%20Lengfeld%2C%20Matthias%20Richter%2C%20and%20Wieland%20Kiess.%20%26%23x201C%3BDoes%20Physiological%20Distribution%20of%20Blood%20Parameters%20in%20Children%20Depend%20on%20Socioeconomic%20Status%3F%20Results%20of%20a%20German%20Cross-Sectional%20Study.%26%23x201D%3B%20%3Ci%3EBMJ%20Open%3C%5C%2Fi%3E%208%2C%20no.%203%20%28March%202018%29%3A%20e019143.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1136%5C%2Fbmjopen-2017-019143%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1136%5C%2Fbmjopen-2017-019143%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Does%20Physiological%20Distribution%20of%20Blood%20Parameters%20in%20Children%20Depend%20on%20Socioeconomic%20Status%3F%20Results%20of%20a%20German%20Cross-Sectional%20Study%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Kristin%22%2C%22lastName%22%3A%22Rieger%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christoph%22%2C%22lastName%22%3A%22Engel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Uta%22%2C%22lastName%22%3A%22Ceglarek%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Kristian%22%2C%22lastName%22%3A%22Harms%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ulrike%22%2C%22lastName%22%3A%22Wurst%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Holger%22%2C%22lastName%22%3A%22Lengfeld%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Matthias%22%2C%22lastName%22%3A%22Richter%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%5D%2C%22abstractNote%22%3A%22%3Cb%3EObjectives%3C%5C%2Fb%3E%20In%20the%20present%20study%2C%20we%20examined%20the%20relation%20between%20socioeconomic%20status%20%28SES%29%20and%20the%20physiological%20distribution%20of%20iron-related%20blood%20parameters.%5Cn%3Cb%3EDesign%3C%5C%2Fb%3E%20This%20is%20a%20cross-sectional%20analysis%20of%20longitudinal%20population-based%20cohort%20study.%5Cn%3Cb%3ESetting%3C%5C%2Fb%3E%20Based%20on%20a%20sample%20of%20healthy%20participants%20from%20a%20German%20research%20centre%2C%20various%20blood%20parameters%20and%20values%20of%20clinical%20examinations%20and%20questionnaires%20were%20collected.%5Cn%3Cb%3EParticipants%3C%5C%2Fb%3E%20A%20total%20of%201206%20healthy%20volunteers%20aged%202.5%20to%2019%20years%2C%20one%20child%20per%20family%20randomly%20selected%2C%20were%20included.%5CnPrimary%20and%20secondary%20outcome%20measures%20%3Cb%3EAssociations%3C%5C%2Fb%3E%20between%20the%20SES%20of%20children%20by%20Winkler-Stolzenberg%20Index%20%28WSI%29%20and%20its%20dimensions%20%28income%2C%20education%2C%20occupation%29%20and%20iron-related%20blood%20parameters%20%28haemoglobin%2C%20ferritin%20and%20transferrin%29%20were%20analysed%20by%20linear%20regression%20analyses.%20Gender%20and%20pubertal%20stage%20were%20included%20as%20covariables.%20Additionally%2C%20associations%20between%20SES%20of%20children%20by%20WSI%20and%20physical%20activity%20%28side-to-side%20jumps%2C%20push-ups%29%20as%20well%20as%20body%20mass%20index%20%28BMI%29%20were%20analysed%20by%20linear%20regression%20analyses.%5Cn%3Cb%3EResults%3C%5C%2Fb%3E%20Children%20with%20high%20WSI%20or%20family%20income%20showed%20significantly%20increased%20z-scores%20for%20haemoglobin%20%28P%3D0.046%3B%20P%3C0.001%29.%20Children%20with%20increased%20WSI%20or%20family%20income%20showed%20significantly%20lower%20z-scores%20for%20transferrin%20%28P%3C0.001%29.%20There%20was%20a%20significant%20correlation%20between%20haemoglobin%20and%20gender%20%28P%3C0.001%29%20and%20between%20transferrin%20and%20pubertal%20stage%20%28P%3D0.024%29.%20Furthermore%2C%20physical%20activity%20was%20positively%20correlated%20and%20BMI%20was%20negatively%20correlated%20with%20WSI%20%28P%3C0.001%29.%5Cn%3Cb%3EDiscussion%3C%5C%2Fb%3E%20Our%20data%20show%20an%20association%20between%20SES%20and%20the%20distribution%20of%20iron-dependent%20parameters.%20Lower%20SES%20is%20correlated%20with%20lower%20values%20for%20haemoglobin%20and%20higher%20values%20for%20transferrin.%20Furthermore%2C%20we%20demonstrate%20that%20physical%20activity%20and%20BMI%20are%20associated%20with%20SES.%20Whereas%20higher%20SES%20is%20correlated%20with%20higher%20values%20for%20physical%20activity%20and%20lower%20BMI.%20Our%20parameters%20are%20standardised%20as%20z-scores%20with%20the%20advantages%20that%20the%20results%20are%20comparable%20across%20different%20age%20groups%20and%20present%20physiological%20courses.%22%2C%22date%22%3A%222018-03%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1136%5C%2Fbmjopen-2017-019143%22%2C%22ISSN%22%3A%222044-6055%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-24T11%3A11%3A47Z%22%7D%7D%2C%7B%22key%22%3A%22BYGWIM5E%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Weithase%20et%20al.%22%2C%22parsedDate%22%3A%222017-04%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EWeithase%2C%20Alexandra%2C%20Mandy%20Vogel%2C%20Henriette%20Kiep%2C%20S%20Schwarz%2C%20Laura%20Mei%26%23xDF%3Bner%2C%20Janine%20Herrmann%2C%20Kristin%20Rieger%2C%20C%20Koch%2C%20Volker%20Schuster%2C%20and%20Wieland%20Kiess.%20%26%23x201C%3B%5BQuality%20of%20and%20Attendance%20at%20Healthy%20Child%20Clinics%20in%20Germany%5D.%26%23x201D%3B%20%3Ci%3EDeutsche%20Medizinische%20Wochenschrift%20%281946%29%3C%5C%2Fi%3E%20142%2C%20no.%208%20%28April%202017%29%3A%20e42%26%23×2013%3B50.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1055%5C%2Fs-0043-100841%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1055%5C%2Fs-0043-100841%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22%5BQuality%20of%20and%20Attendance%20at%20Healthy%20Child%20Clinics%20in%20Germany%5D.%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Alexandra%22%2C%22lastName%22%3A%22Weithase%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Henriette%22%2C%22lastName%22%3A%22Kiep%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22S%22%2C%22lastName%22%3A%22Schwarz%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Laura%22%2C%22lastName%22%3A%22Mei%5Cu00dfner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Janine%22%2C%22lastName%22%3A%22Herrmann%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Kristin%22%2C%22lastName%22%3A%22Rieger%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22C%22%2C%22lastName%22%3A%22Koch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Volker%22%2C%22lastName%22%3A%22Schuster%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%5D%2C%22abstractNote%22%3A%22Europe%20PMC%20is%20an%20archive%20of%20life%20sciences%20journal%20literature.%2C%20%5BQuality%20of%20and%20Attendance%20at%20Healthy%20Child%20Clinics%20in%20Germany%5D.%22%2C%22date%22%3A%222017%5C%2F04%22%2C%22language%22%3A%22English%22%2C%22DOI%22%3A%2210.1055%5C%2Fs-0043-100841%22%2C%22ISSN%22%3A%220012-0472%2C%201439-4413%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Feuropepmc.org%5C%2Farticle%5C%2Fmed%5C%2F28431439%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-27T09%3A01%3A34Z%22%7D%7D%2C%7B%22key%22%3A%222TP45DXF%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Dathan-Stumpf%20et%20al.%22%2C%22parsedDate%22%3A%222016-08%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EDathan-Stumpf%2C%20Anne%2C%20Mandy%20Vogel%2C%20Kristin%20Rieger%2C%20Joachim%20Thiery%2C%20Andreas%20Hiemisch%2C%20and%20Wieland%20Kiess.%20%26%23x201C%3BSerum%20Lipid%20Levels%20Were%20Related%20to%20Socio-Demographic%20Characteristics%20in%20a%20German%20Population-Based%20Child%20Cohort.%26%23x201D%3B%20%3Ci%3EActa%20Paediatrica%3C%5C%2Fi%3E%20105%2C%20no.%208%20%28August%202016%29%3A%20e360%26%23×2013%3B67.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fapa.13438%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fapa.13438%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Serum%20Lipid%20Levels%20Were%20Related%20to%20Socio-Demographic%20Characteristics%20in%20a%20German%20Population-Based%20Child%20Cohort%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anne%22%2C%22lastName%22%3A%22Dathan-Stumpf%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Kristin%22%2C%22lastName%22%3A%22Rieger%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Joachim%22%2C%22lastName%22%3A%22Thiery%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andreas%22%2C%22lastName%22%3A%22Hiemisch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%5D%2C%22abstractNote%22%3A%22%3Cb%3EAim%3C%5C%2Fb%3E%20Socio-demographic%20factors%20affect%20the%20development%20and%20lives%20of%20children%20and%20adolescents.%20We%20examined%20links%20between%20serum%20lipids%20and%20apolipoproteins%20and%20socio-demographic%20factors%20in%20the%20Leipzig%20Research%20Centre%20for%20Civilization%20Diseases%20Child%20%28LIFE%20Child%29%20study%20%3Cb%3EMethods%3C%5C%2Fb%3E%20The%20Winkler%20index%20and%20the%20Family%20Affluence%20Scale%20were%20used%20to%20define%20characteristics%20of%20the%20social%20status%20of%20938%20boys%20and%20860%20girls%20aged%20from%20birth%20to%2019%20years.%20We%20then%20used%20univariate%20and%20multivariate%20regression%20analyses%20to%20examine%20the%20socio-demographic%20impact%20on%20total%20cholesterol%2C%20low-density%20lipoprotein%20%28LDL%29%20cholesterol%2C%20high-density%20lipoprotein%20%28HDL%29%2C%20cholesterol%20triglycerides%20and%20apolipoproteins%20A1%20%28ApoA1%29%20and%20B%20%28ApoB%29.%20%3Cb%3EResults%3C%5C%2Fb%3E%20No%20significant%20influences%20on%20the%20Winkler%20index%20or%20the%20Family%20Affluence%20Scale%20were%20observed%20regarding%20the%20concentrations%20of%20serum%20lipids%20for%20total%20cholesterol%20or%20LDL%20cholesterol.%20However%2C%20and%20most%20importantly%2C%20children%20and%20adolescents%20with%20high%20social%20status%20and%20high%20family%20affluence%20showed%20significantly%20higher%20HDL%20cholesterol%20and%20ApoA1%20levels%20than%20those%20with%20lower%20individual%20totals.%20A%20higher%20Winkler%20index%20was%20associated%20with%20significantly%20lower%20values%20for%20triglycerides%20and%20ApoB.%20%3Cb%3EConclusion%3C%5C%2Fb%3E%20Adolescents%20with%20higher%20family%20wealth%20and%20social%20status%20showed%20a%20lower%20cardiovascular%20risk%20profile%2C%20as%20measured%20by%20the%20concentrations%20of%20HDL%20cholesterol%20and%20triglycerides%20as%20well%20as%20ApoA1%20and%20B.%22%2C%22date%22%3A%22August%2C%202016%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1111%5C%2Fapa.13438%22%2C%22ISSN%22%3A%221651-2227%22%2C%22url%22%3A%22http%3A%5C%2F%5C%2Fonlinelibrary.wiley.com%5C%2Fdoi%5C%2F10.1111%5C%2Fapa.13438%5C%2Fabstract%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-07T07%3A01%3A52Z%22%7D%7D%5D%7D
Petri, Laura, Tanja Poulain, Mandy Vogel, Christof Meigen, Wieland Kiess, and Andreas Hiemisch. “Parent-Perceived Recurrent Pain in Children: Associations with Maternal Pain, Depressiveness, Socioeconomic Status, and Children’s Behavioural Difficulties.” Frontiers in Pediatrics 12 (2024): 1287343. https://doi.org/10.3389/fped.2024.1287343.
Grüning Parache, Laura, Mandy Vogel, Christof Meigen, Wieland Kiess, and Tanja Poulain. “Family Structure, Socioeconomic Status, and Mental Health in Childhood.” European Child & Adolescent Psychiatry, December 26, 2023. https://doi.org/10.1007/s00787-023-02329-y.
Dathan-Stumpf, Anne, Mandy Vogel, Nico Grafe, Wieland Kiess, and Holger Stepan. “Relation between Socioeconomic Status and Maternal Serum Lipids to Infant Lipid Concentrations and Anthropometry in the First Year of Life.” Archives of Gynecology and Obstetrics, March 2, 2023. https://doi.org/10.1007/s00404-023-06937-6.
Philipp, Dariusch, Mandy Vogel, Manuela Brandt, Franziska G. Rauscher, Andreas Hiemisch, Siegfried Wahl, Wieland Kiess, and Tanja Poulain. “The Relationship between Myopia and near Work, Time Outdoors and Socioeconomic Status in Children and Adolescents.” BMC Public Health 22, no. 1 (November 10, 2022): 2058. https://doi.org/10.1186/s12889-022-14377-1.
Schild, Clara Elise, Christof Meigen, Jonas Kappelt, Wieland Kiess, and Tanja Poulain. “Associations between Sociodemographic and Behavioural Parameters and Child Development Depending on Age and Sex: A Cross-Sectional Analysis.” BMJ Open 12, no. 11 (November 1, 2022): e065936. https://doi.org/10.1136/bmjopen-2022-065936.
Poulain, Tanja, Christof Meigen, Wieland Kiess, and Mandy Vogel. “An Online Survey Carried Out in 2022 Showed That Covid-19 Was Associated with Negative Changes in Children’s Lives.” Acta Paediatrica (Oslo, Norway: 1992), June 2, 2022. https://doi.org/10.1111/apa.16435.
Schmidt, Jana, Mandy Vogel, Tanja Poulain, Wieland Kiess, Christian Hirsch, Dirk Ziebolz, and Rainer Haak. “Association of Oral Health Conditions in Adolescents with Social Factors and Obesity.” International Journal of Environmental Research and Public Health 19, no. 5 (January 2022): 2905. https://doi.org/10.3390/ijerph19052905.
Vogel, Mandy, Christof Meigen, Carolin Sobek, Peggy Ober, Ulrike Igel, Antje Körner, Wieland Kiess, and Tanja Poulain. “Well-Being and Covid-19-Related Worries of German Children and Adolescents: A Longitudinal Study from Pre-Covid to the End of Lockdown in Spring 2020.” JCPP Advances 1, no. 1 (March 2021): e12004. https://doi.org/10.1111/jcv2.12004.
Kreusler, Paulina, Mandy Vogel, Anja Willenberg, Ronny Baber, Yvonne Dietz, Antje Körner, Uta Ceglarek, and Wieland Kiess. “Folate and Cobalamin Serum Levels in Healthy Children and Adolescents and Their Association with Age, Sex, Bmi and Socioeconomic Status.” Nutrients 13, no. 2 (February 2021). https://doi.org/10.3390/nu13020546.
Lewien, Christiane, Jon Genuneit, Christof Meigen, Wieland Kiess, and Tanja Poulain. “Sleep-Related Difficulties in Healthy Children and Adolescents.” BMC Pediatrics 21, no. 1 (February 2021): 82. https://doi.org/10.1186/s12887-021-02529-y.
Möller, Siegfried, Tanja Poulain, Antje Körner, Christof Meigen, Anne Jurkutat, Mandy Vogel, Sven Wessela, Andreas Hiemisch, Nico Grafe, and Wieland Kiess. “Motor Skills in Relation to Body-Mass Index, Physical Activity, Tv-Watching, and Socioeconomic Status in German Four-to-17-Year-Old Children.” PloS One 16, no. 5 (2021): e0251738. https://doi.org/10.1371/journal.pone.0251738.
Oelkers, Lea, Mandy Vogel, Agnes Kalenda, Hans Christian Surup, Antje Körner, Jürgen Kratzsch, and Wieland Kiess. “Socioeconomic Status Is Related to Pubertal Development in a German Cohort.” Hormone Research in Paediatrics 93, no. 9–10 (2020): 548–57. https://doi.org/10.1159/000513787.
Poulain, Tanja, Mandy Vogel, and Wieland Kiess. “Review on the Role of Socioeconomic Status in Child Health and Development.” Current Opinion in Pediatrics 32, no. 2 (December 2019): 308–14. https://doi.org/10.1097/MOP.0000000000000876.
Elger, Wieland, Wieland Kiess, Antje Körner, Annett Schrock, Mandy Vogel, and Christian Hirsch. “Influence of Overweight/Obesity, Socioeconomic Status, and Oral Hygiene on Caries in Primary Dentition.” Journal of Investigative and Clinical Dentistry 10, no. 2 (May 2019): e12394. https://doi.org/10.1111/jicd.12394.
Buzek, Theresa, Tanja Poulain, Mandy Vogel, Christoph Engel, Sarah Bussler, Antje Körner, Andreas Hiemisch, and Wieland Kiess. “Relations Between Sleep Duration with Overweight and Academic Stress—Just a Matter of the Socioeconomic Status?” Sleep Health 5, no. 2 (April 1, 2019): 208–15. https://doi.org/10.1016/j.sleh.2018.12.004.
Haas, Myriam, Andreas Hiemisch, Mandy Vogel, Oleg Wagner, Wieland Kiess, and Tanja Poulain. “Sensation Seeking in 3- to 6-Year-Old Children: Associations with Socio-Demographic Parameters and Behavioural Difficulties.” BMC Pediatrics 19, no. 1 (March 2019): 77. https://doi.org/10.1186/s12887-019-1450-6.
Poulain, Tanja, Mandy Vogel, Carolin Sobek, Anja Hilbert, Antje Körner, and Wieland Kiess. “Associations Between Socio-Economic Status and Child Health: Findings of a Large German Cohort Study.” International Journal of Environmental Research and Public Health 16, no. 5 (January 2019): 677. https://doi.org/10.3390/ijerph16050677.
Herrmann, Janine, Mandy Vogel, Diana Pietzner, Esther Kroll, Oleg Wagner, Sarah Schwarz, Eva Müller, Wieland Kiess, Matthias Richter, and Tanja Poulain. “Factors Associated with the Emotional Health of Children: High Family Income as a Protective Factor.” European Child & Adolescent Psychiatry 27, no. 3 (March 2018): 319–28. https://doi.org/10.1007/s00787-017-1049-0.
Rieger, Kristin, Mandy Vogel, Christoph Engel, Uta Ceglarek, Kristian Harms, Ulrike Wurst, Holger Lengfeld, Matthias Richter, and Wieland Kiess. “Does Physiological Distribution of Blood Parameters in Children Depend on Socioeconomic Status? Results of a German Cross-Sectional Study.” BMJ Open 8, no. 3 (March 2018): e019143. https://doi.org/10.1136/bmjopen-2017-019143.
Weithase, Alexandra, Mandy Vogel, Henriette Kiep, S Schwarz, Laura Meißner, Janine Herrmann, Kristin Rieger, C Koch, Volker Schuster, and Wieland Kiess. “[Quality of and Attendance at Healthy Child Clinics in Germany].” Deutsche Medizinische Wochenschrift (1946) 142, no. 8 (April 2017): e42–50. https://doi.org/10.1055/s-0043-100841.
Dathan-Stumpf, Anne, Mandy Vogel, Kristin Rieger, Joachim Thiery, Andreas Hiemisch, and Wieland Kiess. “Serum Lipid Levels Were Related to Socio-Demographic Characteristics in a German Population-Based Child Cohort.” Acta Paediatrica 105, no. 8 (August 2016): e360–67. https://doi.org/10.1111/apa.13438.
2390247
T52N9QLZ
media
1
chicago-fullnote-bibliography
50
date
desc
1
1
6748
https://home.uni-leipzig.de/lifechild/wp-content/plugins/zotpress/
%7B%22status%22%3A%22success%22%2C%22updateneeded%22%3Afalse%2C%22instance%22%3Afalse%2C%22meta%22%3A%7B%22request_last%22%3A0%2C%22request_next%22%3A0%2C%22used_cache%22%3Atrue%7D%2C%22data%22%3A%5B%7B%22key%22%3A%22BT9XFL8H%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Poulain%20et%20al.%22%2C%22parsedDate%22%3A%222024-07-12%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EPoulain%2C%20Tanja%2C%20Cornelia%20Hilbert%2C%20Annelie%20Grundmann%2C%20and%20Wieland%20Kiess.%20%26%23x201C%3BAssociations%20between%20Media%20Use%20at%20Bedtime%20and%20Sleep%3A%20A%20Cross-Sectional%20Analysis%20on%20Differences%20between%20Girls%20and%20Boys.%26%23x201D%3B%20%3Ci%3EFrontiers%20in%20Psychology%3C%5C%2Fi%3E%2015%20%28July%2012%2C%202024%29.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3389%5C%2Ffpsyg.2024.1290935%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3389%5C%2Ffpsyg.2024.1290935%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Associations%20between%20media%20use%20at%20bedtime%20and%20sleep%3A%20a%20cross-sectional%20analysis%20on%20differences%20between%20girls%20and%20boys%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Cornelia%22%2C%22lastName%22%3A%22Hilbert%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Annelie%22%2C%22lastName%22%3A%22Grundmann%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%5D%2C%22abstractNote%22%3A%22%3Csec%20id%3D%5C%22sec1%5C%22%3E%3Ctitle%3EObjectives%3C%5C%2Ftitle%3E%3Cp%3EThis%20study%20investigated%20associations%20between%20the%20use%20of%20electronic%20media%20and%20sleep%20in%20children%20and%20young%20adolescents%2C%20with%20a%20specific%20focus%20on%20the%20moderation%20of%20associations%20by%20sex%20and%20age.%3C%5C%2Fp%3E%3C%5C%2Fsec%3E%3Csec%20id%3D%5C%22sec2%5C%22%3E%3Ctitle%3EMethods%3C%5C%2Ftitle%3E%3Cp%3EBetween%202021%20and%202022%2C%20453%2010-%20to%2014-year-old%20children%20participating%20in%20the%20LIFE%20Child%20cohort%20study%20%28Germany%29%20reported%20on%20their%20use%20of%20electronic%20media%20%28daily%20screen%20time%2C%20use%20at%20bedtime%2C%20device%20ownership%29%20and%20on%20their%20sleep%20difficulties%20%28Sleep%20Self%20Report%29.%20Associations%20between%20media%20use%20and%20sleep%20as%20well%20as%20interactions%20with%20age%20and%20sex%20were%20assessed%20using%20linear%20regression%20analyses.%3C%5C%2Fp%3E%3C%5C%2Fsec%3E%3Csec%20id%3D%5C%22sec3%5C%22%3E%3Ctitle%3EResults%3C%5C%2Ftitle%3E%3Cp%3EThe%20analyses%20revealed%20significant%20associations%20between%20the%20use%20of%20media%20at%20bedtime%20and%20bedtime%20problems%20%28in%20girls%20only%29%2C%20sleep%20behavior%20problems%20%28in%20girls%20only%29%2C%20and%20daytime%20sleepiness%20%28in%20girls%20and%20boys%29.%20Daily%20screen%20time%2C%20in%20contrast%2C%20was%20associated%20with%20none%20of%20the%20sleep%20difficulties.%20The%20number%20of%20media%20devices%20owned%20by%20the%20child%20was%20only%20associated%20with%20bedtime%20problems%20in%20girls%2C%20and%20this%20association%20lost%20statistical%20significance%20once%20media%20use%20at%20bedtime%20was%20included%20as%20further%20predictor.%3C%5C%2Fp%3E%3C%5C%2Fsec%3E%3Csec%20id%3D%5C%22sec4%5C%22%3E%3Ctitle%3EConclusion%3C%5C%2Ftitle%3E%3Cp%3EThe%20findings%20underline%20the%20potentially%20sleep-disturbing%20role%20of%20electronic%20media%20at%20bedtime.%20Furthermore%2C%20they%20suggest%20that%20this%20effect%20is%20more%20pronounced%20in%20girls%20than%20in%20boys.%3C%5C%2Fp%3E%3C%5C%2Fsec%3E%22%2C%22date%22%3A%222024-07-12%22%2C%22language%22%3A%22English%22%2C%22DOI%22%3A%2210.3389%5C%2Ffpsyg.2024.1290935%22%2C%22ISSN%22%3A%221664-1078%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.frontiersin.org%5C%2Fjournals%5C%2Fpsychology%5C%2Farticles%5C%2F10.3389%5C%2Ffpsyg.2024.1290935%5C%2Ffull%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222024-07-18T17%3A24%3A58Z%22%7D%7D%2C%7B%22key%22%3A%22QU74DC8K%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Poulain%20et%20al.%22%2C%22parsedDate%22%3A%222023-02-21%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EPoulain%2C%20Tanja%2C%20Christof%20Meigen%2C%20Wieland%20Kiess%2C%20and%20Mandy%20Vogel.%20%26%23x201C%3BMedia%20Regulation%20Strategies%20in%20Parents%20of%204-%20to%2016-Year-Old%20Children%20and%20Adolescents%3A%20A%20Cross-Sectional%20Study.%26%23x201D%3B%20%3Ci%3EBMC%20Public%20Health%3C%5C%2Fi%3E%2023%2C%20no.%201%20%28February%2021%2C%202023%29%3A%20371.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs12889-023-15221-w%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs12889-023-15221-w%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Media%20regulation%20strategies%20in%20parents%20of%204-%20to%2016-year-old%20children%20and%20adolescents%3A%20a%20cross-sectional%20study%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christof%22%2C%22lastName%22%3A%22Meigen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%5D%2C%22abstractNote%22%3A%22BACKGROUND%3A%20Since%20children%20can%20only%20control%20and%20limit%20their%20own%20media%20use%20to%20a%20limited%20extent%2C%20it%20is%20often%20the%20parents%20who%20regulate%20their%20children%27s%20media%20use.%20However%2C%20there%20is%20insufficient%20research%20on%20which%20strategies%20they%20use%20and%20on%20how%20these%20strategies%20are%20related%20to%20socio-demographic%20and%20behavioral%20parameters.%5CnMETHODS%3A%20The%20parental%20media%20regulation%20strategies%20co-use%2C%20active%20mediation%2C%20restrictive%20mediation%2C%20monitoring%2C%20and%20technical%20mediation%20were%20assessed%20in%20a%20sample%20of%20563%20four-%20to%2016-year-old%20children%20and%20adolescents%20from%20middle%20to%20high%20social%20strata%20participating%20in%20the%20German%20cohort%20study%20LIFE%20Child.%20We%20investigated%20cross-sectional%20associations%20with%20socio-demographic%20characteristics%20%28age%20and%20sex%20of%20child%2C%20age%20of%20parent%2C%20and%20socio-economic%20status%20%28SES%29%29%20and%20other%20behavioral%20parameters%20of%20children%20%28media%20use%2C%20ownership%20of%20media%20devices%2C%20engagement%20in%20extracurricular%20activities%29%20and%20their%20parents%20%28media%20use%29.%5CnRESULTS%3A%20All%20media%20regulation%20strategies%20were%20applied%20frequently%2C%20with%20restrictive%20mediation%20occurring%20most%20frequently.%20Overall%2C%20parents%20of%20younger%20children%20and%20of%20boys%20mediated%20media%20use%20more%20frequently%2C%20while%20we%20observed%20no%20differences%20depending%20on%20SES.%20Regarding%20child%20behavior%2C%20the%20ownership%20of%20a%20smartphone%20and%20a%20tablet%5C%2Fpersonal%20computer%5C%2Flaptop%20was%20associated%20with%20more%20frequent%20technical%20restriction%2C%20while%20screen%20time%20and%20engagement%20in%20extracurricular%20activities%20was%20not%20associated%20with%20parental%20media%20regulation.%20In%20contrast%2C%20parental%20screen%20time%20was%20related%20to%20more%20frequent%20co-use%20and%20less%20frequent%20use%20of%20restrictive%20and%20technical%20mediation.%5CnCONCLUSION%3A%20Parental%20regulation%20of%20child%20media%20use%20is%20influenced%20by%20parental%20attitudes%20and%20a%20perceived%20need%20for%20mediation%20%28e.g.%2C%20in%20younger%20children%20or%20children%20owning%20internet-enabled%20devices%29%20rather%20than%20child%20behavior.%22%2C%22date%22%3A%222023-02-21%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1186%5C%2Fs12889-023-15221-w%22%2C%22ISSN%22%3A%221471-2458%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-24T11%3A01%3A01Z%22%7D%7D%2C%7B%22key%22%3A%22F5UB8HWZ%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Kliesener%20et%20al.%22%2C%22parsedDate%22%3A%222022-03%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EKliesener%2C%20Tobias%2C%20Christof%20Meigen%2C%20Wieland%20Kiess%2C%20and%20Tanja%20Poulain.%20%26%23x201C%3BAssociations%20Between%20Problematic%20Smartphone%20Use%20and%20Behavioural%20Difficulties%2C%20Quality%20of%20Life%2C%20and%20School%20Performance%20Among%20Children%20and%20Adolescents.%26%23x201D%3B%20%3Ci%3EBMC%20Psychiatry%3C%5C%2Fi%3E%2022%2C%20no.%201%20%28March%202022%29%3A%201%26%23×2013%3B12.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs12888-022-03815-4%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs12888-022-03815-4%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Associations%20Between%20Problematic%20Smartphone%20Use%20and%20Behavioural%20Difficulties%2C%20Quality%20of%20Life%2C%20and%20School%20Performance%20Among%20Children%20and%20Adolescents%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tobias%22%2C%22lastName%22%3A%22Kliesener%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christof%22%2C%22lastName%22%3A%22Meigen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%5D%2C%22abstractNote%22%3A%22European%20studies%20on%20determinants%20and%20factors%20associated%20with%20problematic%20smartphone%20use%20%28PSU%29%20in%20children%20and%20adolescents%20are%20still%20sparse.%20This%20study%20reports%20the%20current%20amount%20of%20PSU%20symptoms%20and%20the%20presence%20of%20%28clinically%20relevant%29%20PSU%20in%20German%20children%20and%20adolescents.%20We%20also%20investigated%20associations%20between%20socio-demographic%20factors%2C%20different%20smartphone%20usage%20patterns%2C%20and%20daily%20smartphone%20usage%20time%20and%20the%20amount%20of%20PSU%20symptoms%20in%20this%20group.%20In%20addition%2C%20associations%20of%20PSU%20symptoms%20and%20high%20smartphone%20usage%20times%20%28%3E%202%20h%5C%2Fday%29%20with%20behavioural%20problems%2C%20quality%20of%20life%20%28QoL%29%2C%20and%20school%20performance%20were%20investigated.%20Within%20the%20framework%20of%20the%20LIFE%20Child%20study%2C%20564%20children%20and%20adolescents%20aged%2010%5Cu201318%20years%20provided%20information%20on%20PSU%20symptoms%20%28using%20the%20Smartphone%20Addiction%20Proneness%20Scale%29%2C%20daily%20smartphone%20usage%20time%2C%20smartphone%20activities%2C%20behavioural%20strengths%20and%20difficulties%20%28using%20the%20Strengths%20and%20Difficulties%20Questionnaire%29%2C%20QoL%20%28using%20the%20KIDSCREEN-27%29%2C%20and%20school%20performance.%20Multiple%20regression%20analyses%20were%20applied%20to%20assess%20associations.%20In%20the%20present%20sample%2C%20PSU%20was%20present%20in%2013%20children%20%282.3%25%29.%20Older%20age%2C%20female%20gender%2C%20high%20daily%20smartphone%20usage%20time%20of%20%3E%202%20h%2C%20and%20intensive%20smartphone%20use%20for%20social%20networking%2C%20gaming%2C%20or%20watching%20video%20clips%20were%20significantly%20associated%20with%20more%20PSU%20symptoms.%20Children%20and%20adolescents%20reporting%20more%20PSU%20symptoms%20also%20showed%20lower%20QoL%2C%20more%20behavioural%20difficulties%2C%20and%20poorer%20school%20performance%2C%20independently%20of%20age%2C%20gender%2C%20socio-economic%20status%2C%20and%20daily%20smartphone%20usage%20time.%20In%20contrast%2C%20daily%20smartphone%20usage%20time%20per%20se%20showed%20only%20weak%20or%20non-significant%20associations%20with%20these%20aspects%20of%20health%20and%20behaviour.%20Intensive%20smartphone%20use%20for%20entertainment%20may%20increase%20the%20risk%20of%20developing%20PSU%20symptoms.%20Furthermore%2C%20the%20results%20indicate%20that%20PSU%20symptoms%20%28more%20than%20long%20smartphone%20usage%20times%20per%20se%29%20are%20associated%20with%20more%20behavioural%20difficulties%20and%20poorer%20QoL.%22%2C%22date%22%3A%222022%5C%2F03%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1186%5C%2Fs12888-022-03815-4%22%2C%22ISSN%22%3A%221471-244X%22%2C%22url%22%3A%22http%3A%5C%2F%5C%2Fbmcpsychiatry.biomedcentral.com%5C%2Farticles%5C%2F10.1186%5C%2Fs12888-022-03815-4%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222024-08-27T13%3A16%3A23Z%22%7D%7D%2C%7B%22key%22%3A%22HJKZ645K%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Poulain%20et%20al.%22%2C%22parsedDate%22%3A%222021-09%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EPoulain%2C%20Tanja%2C%20Mandy%20Vogel%2C%20Tobias%20Kliesener%2C%20and%20Wieland%20Kiess.%20%26%23x201C%3BAssociations%20Between%20Changes%20in%20Behavioral%20Difficulties%20and%20Levels%20of%20Problematic%20Smartphone%20Use%20in%20Adolescents%20Over%20a%201-Year%20Period.%26%23x201D%3B%20%3Ci%3EEuropean%20Child%20%26amp%3B%20Adolescent%20Psychiatry%3C%5C%2Fi%3E%20online%20ahead%20of%20print%20%28September%202021%29.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs00787-021-01874-8%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs00787-021-01874-8%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Associations%20Between%20Changes%20in%20Behavioral%20Difficulties%20and%20Levels%20of%20Problematic%20Smartphone%20Use%20in%20Adolescents%20Over%20a%201-Year%20Period%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tobias%22%2C%22lastName%22%3A%22Kliesener%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%5D%2C%22abstractNote%22%3A%22OBJECTIVES%3A%20The%20present%20longitudinal%20study%20investigates%20associations%20between%20changes%20in%20externalizing%20and%20internalizing%20behavioral%20difficulties%20and%20changes%20in%20problematic%20smartphone%20usage%20within%20the%20same%201-year%20period%20in%20healthy%20adolescents.%5CnMETHODS%3A%20The%20project%20is%20part%20of%20the%20LIFE%20Child%20cohort%20study%20conducted%20in%20Leipzig%2C%20Germany.%20Ten-%20to%2016-year-old%20adolescents%20%28n%5Cu2009%3D%5Cu2009363%29%20provided%20information%20on%20behavioral%20difficulties%20%5BStrengths%20and%20Difficulties%20Questionnaire%20%28SDQ%29%5D%2C%20the%20duration%20of%20daily%20smartphone%20use%2C%20and%20symptoms%20of%20smartphone%20addiction%20%5BSmartphone%20Addiction%20Proneness%20Scale%20%28SAPS%29%5D%20at%20two%20consecutive%20study%20visits%2C%20t1%20and%20t2%20%281%5Cu00a0year%20after%20t1%29.%20In%20the%20first%20of%20two%20analysis%20phases%2C%20we%20applied%20linear%20regression%20analyses%20to%20assess%20cross-sectional%20associations%20between%20externalizing%20and%20internalizing%20behavioral%20difficulties%20and%20the%20duration%20of%20smartphone%20use%20and%20symptoms%20of%20smartphone%20addiction%20%28at%20t1%20and%20t2%29.%20In%20the%20second%2C%20we%20assessed%20associations%20between%20the%20changes%20measured%20in%20these%20variables%20over%20the%20period%20of%20a%20year.%20All%20associations%20were%20adjusted%20for%20age%2C%20sex%2C%20and%20soci-economic%20status.%5CnRESULTS%3A%20Children%20who%20reported%20prolonged%20periods%20of%20smartphone%20use%20or%20more%20symptoms%20of%20smartphone%20addiction%20exhibited%20significantly%20higher%20levels%20of%20externalizing%20and%20internalizing%20behavioral%20difficulties%20at%20t1%20and%20t2.%20Further%2C%20children%20who%20increased%20their%20usage%20or%20developed%20addiction%20symptoms%20between%20t1%20and%20t2%20also%20developed%20more%20externalizing%20behavioral%20difficulties.%20We%20found%20the%20same%20tendencies%20in%20regard%20to%20internalizing%20behavioral%20difficulties%2C%20although%20the%20associations%20did%20not%20reach%20statistical%20significance.%5CnCONCLUSIONS%3A%20The%20present%20findings%20suggest%20that%20externalizing%20behavioral%20difficulties%20and%20problematic%20smartphone%20use%20are%20mutually%20dependent%20in%20the%20long%20term.%22%2C%22date%22%3A%222021-09%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1007%5C%2Fs00787-021-01874-8%22%2C%22ISSN%22%3A%221435-165X%22%2C%22url%22%3A%22http%3A%5C%2F%5C%2Forgid.org%5C%2F10.1007%5C%2Fs00787-021-01874-8%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-07T07%3A01%3A31Z%22%7D%7D%2C%7B%22key%22%3A%226ZLGKVAT%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Schwarzer%20et%20al.%22%2C%22parsedDate%22%3A%222021-03%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3ESchwarzer%2C%20Clarissa%2C%20Nico%20Grafe%2C%20Andreas%20Hiemisch%2C%20Wieland%20Kiess%2C%20and%20Tanja%20Poulain.%20%26%23x201C%3BAssociations%20of%20Media%20Use%20and%20Early%20Childhood%20Development%3A%20Cross-Sectional%20Findings%20from%20the%20Life%20Child%20Study.%26%23x201D%3B%20%3Ci%3EPediatric%20Research%3C%5C%2Fi%3E%20online%20ahead%20of%20print%20%28March%202021%29.%20%3Ca%20class%3D%27zp-ItemURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1038%5C%2Fs41390-021-01433-6%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1038%5C%2Fs41390-021-01433-6%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Associations%20of%20Media%20Use%20and%20Early%20Childhood%20Development%3A%20Cross-Sectional%20Findings%20from%20the%20Life%20Child%20Study%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Clarissa%22%2C%22lastName%22%3A%22Schwarzer%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Nico%22%2C%22lastName%22%3A%22Grafe%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andreas%22%2C%22lastName%22%3A%22Hiemisch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%5D%2C%22abstractNote%22%3A%22BACKGROUND%3A%20Excessive%20media%20usage%20affects%20children%27s%20health.%20This%20study%20investigated%20associations%20between%20children%27s%20and%20mother%27s%20media%20use%2C%20parent-child%20interactions%2C%20and%20early-childhood%20development%20outcomes.%5CnMETHODS%3A%20Two%20hundred%20and%20ninety-six%20healthy%202-5-year-old%20preschoolers%20%2852.4%25%20male%2C%20mean%20age%5Cu2009%3D%5Cu20093.5%20years%29%20and%20224%20mothers%20from%20the%20LIFE%20Child%20cohort%20study%20were%20analyzed.%20Screen%20times%20and%20parent-child%20interactions%20were%20assessed%20using%20standardized%20parental%20questionnaires.%20Developmental%20skills%20were%20investigated%20using%20the%20standardized%20development%20test%20ET%206-6-R.%5CnRESULTS%3A%20High%20screen%20times%20in%20children%20%28%3E1%5Cu2009h%5C%2Fday%29%20were%20significantly%20associated%20with%20lower%20percentile%20ranks%20in%20cognition%20%28b%20%3D%20-10.96%2C%20p%5Cu2009%3C%5Cu20090.01%29%2C%20language%20%28b%5Cu2009%3D%5Cu2009-12.88%2C%20p%5Cu2009%3C%5Cu20090.01%29%2C%20and%20social-emotional%20skills%20%28b%5Cu2009%3D%5Cu2009-7.80%2C%20p%5Cu2009%3D%5Cu20090.05%29.%20High%20screen%20times%20in%20mothers%20%28%3E5%5Cu2009h%5C%2Fday%29%20were%20significantly%20associated%20with%20high%20media%20use%20by%20children%20%28OR%5Cu2009%3D%5Cu20093.86%2C%20p%5Cu2009%3C%5Cu20090.01%29.%20Higher%20parent-child%20interaction%20scores%20were%20significantly%20associated%20with%20better%20body%20motor%20%28b%5Cu2009%3D%5Cu20090.41%2C%20p%5Cu2009%3D%5Cu20090.05%29%2C%20cognition%20%28b%5Cu2009%3D%5Cu20090.57%2C%20p%5Cu2009%3C%5Cu20090.01%29%2C%20language%20%28b%5Cu2009%3D%5Cu20090.48%2C%20p%5Cu2009%3D%5Cu20090.02%29%2C%20and%20social-emotional%20outcomes%20%28b%5Cu2009%3D%5Cu20090.80%2C%20p%5Cu2009%3C%5Cu20090.01%29%20in%20children.%5CnCONCLUSIONS%3A%20Public%20health%20strategies%20should%20seek%20to%20educate%20caregivers%20as%20competent%20mediators%20for%20their%20children%27s%20media%20habits%2C%20with%20focus%20on%20the%20need%20for%20children%20to%20have%20frequent%20parent-child%20interactions.%5CnIMPACT%3A%20High%20media%20usage%20in%20children%20is%20related%20to%20poorer%20cognition%2C%20language%2C%20and%20social-emotional%20skills.%20More%20frequent%20parent-child%20interactions%20are%20associated%20with%20better%20body%20motor%2C%20cognition%2C%20language%2C%20and%20social-emotional%20skills%20in%20children.%20High%20level%20of%20media%20use%20in%20mothers%20is%20not%20directly%20related%20to%20children%27s%20development%20outcomes%20but%20is%20directly%20related%20to%20high%20media%20usage%20of%20children.%20Public%20health%20strategies%20should%20seek%20to%20raise%20media%20awareness%20and%20management%20in%20both%20parents%20and%20children.%22%2C%22date%22%3A%222021-03%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1038%5C%2Fs41390-021-01433-6%22%2C%22ISSN%22%3A%221530-0447%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1038%5C%2Fs41390-021-01433-6%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-07T07%3A01%3A24Z%22%7D%7D%2C%7B%22key%22%3A%226MPTPUJJ%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Poulain%20et%20al.%22%2C%22parsedDate%22%3A%222021-03%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EPoulain%2C%20Tanja%2C%20Christof%20Meigen%2C%20Carolin%20Sobek%2C%20Peggy%20Ober%2C%20Ulrike%20Igel%2C%20Antje%20K%26%23xF6%3Brner%2C%20Wieland%20Kiess%2C%20and%20Mandy%20Vogel.%20%26%23x201C%3BLoss%20of%20Childcare%20and%20Classroom%20Teaching%20During%20the%20Covid-19-Related%20Lockdown%20in%20Spring%202020%3A%20A%20Longitudinal%20Study%20on%20Consequences%20on%20Leisure%20Behavior%20and%20Schoolwork%20at%20Home.%26%23x201D%3B%20%3Ci%3EPloS%20One%3C%5C%2Fi%3E%2016%2C%20no.%203%20%28March%202021%29%3A%20e0247949.%20%3Ca%20class%3D%27zp-ItemURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1371%5C%2Fjournal.pone.0247949%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1371%5C%2Fjournal.pone.0247949%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Loss%20of%20Childcare%20and%20Classroom%20Teaching%20During%20the%20Covid-19-Related%20Lockdown%20in%20Spring%202020%3A%20A%20Longitudinal%20Study%20on%20Consequences%20on%20Leisure%20Behavior%20and%20Schoolwork%20at%20Home%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christof%22%2C%22lastName%22%3A%22Meigen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Carolin%22%2C%22lastName%22%3A%22Sobek%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Peggy%22%2C%22lastName%22%3A%22Ober%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ulrike%22%2C%22lastName%22%3A%22Igel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%5D%2C%22abstractNote%22%3A%22AIM%3A%20In%20spring%202020%2C%20the%20first%20Covid-19-related%20lockdown%20included%20the%20closing%20of%20kindergartens%20and%20schools.%20Home%20schooling%2C%20the%20lack%20of%20social%20contacts%20with%20peers%20and%20the%20care%20of%20the%20children%20at%20home%20posed%20an%20enormous%20challenge%20for%20many%20families.%5CnMETHODS%3A%20The%20present%20study%20investigated%20the%20leisure%20behavior%20of%20285%20one-%20to%2010-year-old%20German%20children%20at%20two%20time%20points%20%28t1%20and%20t2%29%20during%20the%20Covid-19-related%20lockdown%20in%20spring%202020.%20In%20the%20subsample%20of%20primary%20school%20children%20%28n%20%3D%20102%29%2C%20we%20also%20explored%20children%27s%20attitudes%20towards%20schoolwork%20at%20home.%20Analyses%20focused%20on%20the%20change%20of%20behavior%20from%20t1%20to%20t2%2C%20on%20differences%20in%20these%20changes%20depending%20on%20socio-economic%20status%20%28SES%29%2C%20and%20on%20associations%20of%20behavior%20with%20SES%2C%20the%20number%20of%20children%20at%20home%2C%20and%20the%20frequency%20of%20receiving%20learning%20materials%20from%20school.%5CnRESULTS%3A%20While%20the%20frequency%20of%20playing%20outside%20increased%20significantly%20from%20t1%20to%20t2%2C%20the%20frequency%20of%20handicrafts%2C%20playing%20board%20games%2C%20indoor%20sports%2C%20and%20motivation%20to%20do%20schoolwork%20decreased.%20The%20observed%20changes%20between%20t1%20and%20t2%20did%20not%20differ%20depending%20on%20SES.%20However%2C%20a%20lower%20SES%20was%20associated%20with%20higher%20media%20use%2C%20less%20outdoor%20activity%2C%20and%20%28though%20only%20marginally%20significant%29%20a%20reduced%20time%20doing%20schoolwork%20and%20a%20reduced%20ability%20to%20concentrate%20on%20schoolwork%20at%20t1.%20In%20households%20with%20more%20children%2C%20children%20played%20outside%20more%20often%2C%20but%20were%20read%20to%20less%20frequently%20and%20%28though%20only%20marginally%20significant%29%20watched%20movies%20and%20series%20less%20frequently.%20Children%20receiving%20learning%20materials%20from%20school%20on%20a%20regular%20basis%20spent%20significantly%20more%20time%20doing%20schoolwork%20at%20home%20than%20children%20receiving%20materials%20only%20irregularly.%5CnCONCLUSIONS%3A%20A%20continuing%20loss%20of%20childcare%20in%20day-care%20facilities%20and%20schools%20entails%20the%20danger%20of%20declining%20education%20in%20the%20form%20of%20%28inter%29active%20indoor%20activities%20and%20schoolwork.%22%2C%22date%22%3A%222021-03%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1371%5C%2Fjournal.pone.0247949%22%2C%22ISSN%22%3A%221932-6203%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1371%5C%2Fjournal.pone.0247949%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-24T11%3A01%3A24Z%22%7D%7D%2C%7B%22key%22%3A%226AVE9W3V%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Vogel%20et%20al.%22%2C%22parsedDate%22%3A%222021-03%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EVogel%2C%20Mandy%2C%20Christof%20Meigen%2C%20Carolin%20Sobek%2C%20Peggy%20Ober%2C%20Ulrike%20Igel%2C%20Antje%20K%26%23xF6%3Brner%2C%20Wieland%20Kiess%2C%20and%20Tanja%20Poulain.%20%26%23x201C%3BWell-Being%20and%20Covid-19-Related%20Worries%20of%20German%20Children%20and%20Adolescents%3A%20A%20Longitudinal%20Study%20from%20Pre-Covid%20to%20the%20End%20of%20Lockdown%20in%20Spring%202020.%26%23x201D%3B%20%3Ci%3EJCPP%20Advances%3C%5C%2Fi%3E%201%2C%20no.%201%20%28March%202021%29%3A%20e12004.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fjcv2.12004%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fjcv2.12004%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Well-Being%20and%20Covid-19-Related%20Worries%20of%20German%20Children%20and%20Adolescents%3A%20A%20Longitudinal%20Study%20from%20Pre-Covid%20to%20the%20End%20of%20Lockdown%20in%20Spring%202020%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christof%22%2C%22lastName%22%3A%22Meigen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Carolin%22%2C%22lastName%22%3A%22Sobek%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Peggy%22%2C%22lastName%22%3A%22Ober%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ulrike%22%2C%22lastName%22%3A%22Igel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%5D%2C%22abstractNote%22%3A%22Background%20There%20is%20concern%20that%20pandemic%20measures%20put%20a%20strain%20on%20the%20health%20and%20well-being%20of%20children.%20We%20investigated%20the%20effects%20of%20the%20COVID-19%20pandemic%2C%20the%20lockdown%2C%20and%20social%20distancing%20on%20the%20well-being%2C%20media%20use%2C%20and%20emotions%20of%20children%20and%20adolescents%20between%209%20and%2018%20years.%20Methods%20We%20used%20linear%20and%20proportional%20odds%20logistic%20regression%20correcting%20for%20age%2C%20sex%2C%20and%20socioeconomic%20status%20%28SES%29%20and%20to%20compare%20media%20use%2C%20peers%5C%2Fsocial%20support%2C%20physical%2C%20and%20psychological%20well-being%20between%202019%20%28pre-COVID%20baseline%29%20and%20two%20time%20points%20shortly%20after%20the%20start%20of%20the%20lockdown%20%28last%20week%20of%20March%20and%20April%202020%2C%20respectively%29%20in%20391%209%5Cu201319-year-old%20healthy%20children%20and%20adolescents%20of%20the%20LIFE%20Child%20cohort.%20COVID-19-related%20feelings%20and%20their%20relationship%20to%20age%2C%20sex%2C%20and%20SES%20were%20assessed%20at%20two%20time%20points%20during%20lockdown.%20Results%20We%20found%20significantly%20lower%20scores%20in%20physical%20and%20psychological%20well-being%20during%20lockdown%20compared%20to%20baseline.%20The%20effect%20was%20significantly%20stronger%20in%20children%20with%20medium%5C%2Flow%20SES.%20Perceived%20social%20support%20scores%20were%20also%20significantly%20lower%20during%20the%20lockdown.%20The%20percentage%20of%20children%20who%20had%20no%20contact%20with%20their%20peers%20%28in-person%20or%20online%29%20increased%20from%203%25%20pre-COVID%20to%2014%25%20and%2013%25%20in%20April%20and%20March%202020%2C%20respectively.%20About%2080%25%20of%20the%20children%20missed%20in-person%20contacts%20with%20friends.%20Most%20of%20the%20children%20worried%20more%20about%20the%20health%20of%20their%20families%20than%20their%20own.%20Sixty%20percent%20worried%20about%20the%20international%20situation%20at%20least%20moderately%2C%20whereas%20only%2020%25%20were%20afraid%20of%20COVID-19%20itself.%20The%20percentage%20of%20children%20who%20believed%20it%20would%20never%20be%20as%20before%20COVID-19%20rose%20from%207.4%25%20at%20the%20beginning%20lockdown%20end%20of%20March%20to%2016.2%25%20a%20month%20later.%20In%20contrast%2C%20all%20other%20COVID-19-related%20worries%2C%20showed%20a%20%28nonsignificant%29%20decline%20during%20the%20same%20period.%20Conclusion%20Our%20study%20supports%20the%20notion%20that%20pandemic%20measures%20have%20to%20be%20balanced%20against%20adverse%20public%20health%20effects.%20Especially%20vulnerable%20groups%20have%20to%20be%20protected.%22%2C%22date%22%3A%222021-03%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1111%5C%2Fjcv2.12004%22%2C%22ISSN%22%3A%222692-9384%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Facamh.onlinelibrary.wiley.com%5C%2Fdoi%5C%2Fabs%5C%2F10.1111%5C%2Fjcv2.12004%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-24T13%3A37%3A39Z%22%7D%7D%2C%7B%22key%22%3A%22KISPREAQ%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Poulain%20et%20al.%22%2C%22parsedDate%22%3A%222020-08%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EPoulain%2C%20Tanja%2C%20Carolin%20Sobek%2C%20Juliane%20Ludwig%2C%20Ulrike%20Igel%2C%20Gesine%20Grande%2C%20Verena%20Ott%2C%20Wieland%20Kiess%2C%20Antje%20K%26%23xF6%3Brner%2C%20and%20Mandy%20Vogel.%20%26%23x201C%3BAssociations%20of%20Green%20Spaces%20and%20Streets%20in%20the%20Living%20Environment%20with%20Outdoor%20Activity%2C%20Media%20Use%2C%20Overweight%5C%2FObesity%20and%20Emotional%20Wellbeing%20in%20Children%20and%20Adolescents.%26%23x201D%3B%20%3Ci%3EInternational%20Journal%20of%20Environmental%20Research%20and%20Public%20Health%3C%5C%2Fi%3E%2017%2C%20no.%2017%20%28August%202020%29%3A%206321.%20%3Ca%20class%3D%27zp-ItemURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Fijerph17176321%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Fijerph17176321%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Associations%20of%20Green%20Spaces%20and%20Streets%20in%20the%20Living%20Environment%20with%20Outdoor%20Activity%2C%20Media%20Use%2C%20Overweight%5C%2FObesity%20and%20Emotional%20Wellbeing%20in%20Children%20and%20Adolescents%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Carolin%22%2C%22lastName%22%3A%22Sobek%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Juliane%22%2C%22lastName%22%3A%22Ludwig%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ulrike%22%2C%22lastName%22%3A%22Igel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Gesine%22%2C%22lastName%22%3A%22Grande%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Verena%22%2C%22lastName%22%3A%22Ott%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%5D%2C%22abstractNote%22%3A%22Aspects%20of%20the%20living%20environment%20can%20affect%20health%20and%20wellbeing%20of%20children%20and%20adolescents.%20Whereas%20most%20previous%20studies%20assessed%20the%20more%20distant%20residential%20urban%20environment%2C%20less%20is%20known%20on%20possible%20effects%20of%20the%20close%20environment.%20The%20present%20study%20investigated%20associations%20of%20the%20proportion%20of%20streets%20and%20green%20spaces%20in%20the%20immediate%20urban%20living%20environment%20%2850%2C%20100%20and%20400%20m%20around%20the%20home%29%20with%20media%20use%2C%20outdoor%20activity%2C%20overweight%5C%2Fobesity%20and%20emotional%20problems%20in%20two%20samples%20of%20younger%20%28age%203-10%2C%20n%20%3D%20395%29%20and%20older%20children%20%28age%2010-19%2C%20n%20%3D%20405%29.%20Independently%20of%20socioeconomic%20parameters%2C%20a%20higher%20proportion%20of%20streets%20was%20associated%20with%20overweight%5C%2Fobesity%20%28in%20younger%20and%20older%20children%29%2C%20higher%20media%20use%20%28in%20younger%20children%29%2C%20less%20outdoor%20activity%20and%20more%20emotional%20problems%20%28in%20older%20children%29.%20Older%20children%27s%20outdoor%20activity%20in%20winter%20increased%20with%20increasing%20proportions%20of%20green%20spaces.%20The%20observations%20suggest%20that%20the%20immediate%20urban%20living%20environment%20is%20a%20factor%20that%20can%20affect%20leisure%20behavior%20and%20health%20in%20children.%22%2C%22date%22%3A%22Aug%2C%202020%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.3390%5C%2Fijerph17176321%22%2C%22ISSN%22%3A%221660-4601%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Fijerph17176321%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-24T11%3A01%3A53Z%22%7D%7D%2C%7B%22key%22%3A%228S9Z73TW%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Poulain%20et%20al.%22%2C%22parsedDate%22%3A%222020%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EPoulain%2C%20Tanja%2C%20Mandy%20Vogel%2C%20Christof%20Meigen%2C%20Ulrike%20Spielau%2C%20Andreas%20Hiemisch%2C%20and%20Wieland%20Kiess.%20%26%23x201C%3BParent-Child%20Agreement%20in%20Different%20Domains%20of%20Child%20Behavior%20and%20Health.%26%23x201D%3B%20%3Ci%3EPloS%20One%3C%5C%2Fi%3E%2015%2C%20no.%204%20%282020%29%3A%20e0231462.%20%3Ca%20class%3D%27zp-ItemURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1371%5C%2Fjournal.pone.0231462%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1371%5C%2Fjournal.pone.0231462%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Parent-Child%20Agreement%20in%20Different%20Domains%20of%20Child%20Behavior%20and%20Health%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christof%22%2C%22lastName%22%3A%22Meigen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ulrike%22%2C%22lastName%22%3A%22Spielau%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andreas%22%2C%22lastName%22%3A%22Hiemisch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%5D%2C%22abstractNote%22%3A%22AIM%3A%20The%20present%20study%20aimed%20to%20investigate%20and%20compare%20parent-child%20agreement%20in%20different%20domains%20of%20child%20health%20and%20behavior.%5CnMETHODS%3A%20Data%20were%20collected%20between%202011%20and%202019%20within%20the%20framework%20of%20the%20LIFE%20Child%20study%20%28Germany%29.%20Different%20subgroups%20of%2010-%20to%2012-year-old%20children%20and%20their%20parents%20%28n%20%28max%29%20%3D%20692%29%20completed%20questionnaires%20on%20several%20health%20behaviors%20%28diet%2C%20media%20use%2C%20physical%20activity%2C%20sleep%29%2C%20parameters%20of%20health%20%28behavioral%20strengths%20and%20difficulties%2C%20psychosomatic%20complaints%29%2C%20and%20school%20grades.%20Agreement%20between%20child%20and%20parent%20reports%20was%20evaluated%20using%20weighted%20kappa%20coefficients.%20Furthermore%2C%20the%20frequencies%20of%20different%20types%20of%20%28dis%29agreement%20%28parent%20report%20%3E%20child%20report%2C%20same%20response%2C%20child%20report%20%3E%20parent%20report%29%20were%20assessed%20and%20checked%20for%20associations%20with%20child%20or%20parent%20gender.%5CnRESULTS%3A%20Agreement%20between%20child%20and%20parent%20reports%20varied%20from%20low%20to%20almost%20perfect%2C%20with%20the%20greatest%20levels%20of%20agreement%20for%20school%20grades%20and%20organized%20physical%20activity%2C%20and%20the%20lowest%20for%20dizziness%2C%20sleep%20duration%2C%20and%20the%20consumption%20of%20potatoes.%20Child%20gender%20had%20no%20significant%20effect%20on%20parent-child%20agreement.%20In%20contrast%2C%20the%20findings%20suggest%20that%20parent%20gender%20had%20some%20effect%20on%20agreement%20levels%2C%20with%20higher%20agreement%20for%20certain%20psychosomatic%20complaints%20when%20parent%20reports%20were%20completed%20by%20the%20mother%2C%20and%20higher%20agreement%20for%20white%20bread%20consumption%20if%20they%20were%20completed%20by%20the%20father.%20For%20some%20of%20the%20questionnaire%20items%20%28especially%20those%20relating%20to%20behavioral%20difficulties%20and%20psychosomatic%20complaints%2C%20but%20also%20to%20the%20consumption%20of%20individual%20food%20products%20and%20mobile%20phone%20use%29%2C%20the%20type%20of%20%28dis%29agreement%20differed%20depending%20on%20child%20or%20parent%20gender.%5CnCONCLUSIONS%3A%20The%20findings%20suggest%20that%20the%20perceptions%20and%20reporting%20strategies%20of%20children%20and%20their%20parents%20can%20diverge%20considerably%2C%20in%20particular%20for%20behavior%20that%20is%20not%20easily%20observable%20or%20measurable.%22%2C%22date%22%3A%222020%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1371%5C%2Fjournal.pone.0231462%22%2C%22ISSN%22%3A%221932-6203%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1371%5C%2Fjournal.pone.0231462%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-24T11%3A05%3A20Z%22%7D%7D%2C%7B%22key%22%3A%22WNXW7BER%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Poulain%20et%20al.%22%2C%22parsedDate%22%3A%222019-12%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EPoulain%2C%20Tanja%2C%20Mandy%20Vogel%2C%20Theresa%20Buzek%2C%20Jon%20Genuneit%2C%20Andreas%20Hiemisch%2C%20and%20Wieland%20Kiess.%20%26%23x201C%3BReciprocal%20Longitudinal%20Associations%20Between%20Adolescents%26%23×2019%3B%20Media%20Consumption%20and%20Sleep.%26%23x201D%3B%20%3Ci%3EBehavioral%20Sleep%20Medicine%3C%5C%2Fi%3E%2017%2C%20no.%206%20%28December%202019%29%3A%20763%26%23×2013%3B77.%20%3Ca%20class%3D%27zp-ItemURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1080%5C%2F15402002.2018.1491851%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1080%5C%2F15402002.2018.1491851%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Reciprocal%20Longitudinal%20Associations%20Between%20Adolescents%27%20Media%20Consumption%20and%20Sleep%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Theresa%22%2C%22lastName%22%3A%22Buzek%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jon%22%2C%22lastName%22%3A%22Genuneit%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andreas%22%2C%22lastName%22%3A%22Hiemisch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%5D%2C%22abstractNote%22%3A%22Background%5C%2FObjective%3A%20Associations%20between%20adolescents%27%20sleep%20and%20their%20media%20consumption%20have%20been%20shown%20in%20several%20cross-sectional%20studies.%20However%2C%20longitudinal%20investigations%20are%20still%20sparse%20and%20have%20mainly%20investigated%20associations%20between%20sleep%20duration%20and%20the%20usage%20of%20TV%20or%20computer%20games.%20The%20present%20study%20explored%20reciprocal%20longitudinal%20relationships%20between%20the%20consumption%20of%20different%20screen-based%20media%20and%20sleep-related%20problems%20in%20German%20adolescents.%20Participants%3A%20Four%20hundred%20sixty-seven%2010-%20to%2017-year-old%20adolescents%20participated%20in%20the%20LIFE%20Child%20Study%20in%20Leipzig%2C%20Germany.%20Methods%3A%20The%20consumption%20of%20screen-based%20media%20%28TV%20or%20video%2C%20computer%20and%20Internet%2C%20mobile%20phones%29%20as%20well%20as%20sleep-related%20problems%20%28problems%20at%20bedtime%2C%20sleep%20behavior%20problems%2C%20daytime%20sleepiness%29%20were%20assessed%20at%20two%20time%20points%2C%2012%5Cu00a0months%20apart.%20Reciprocal%20longitudinal%20relations%20were%20assessed%20by%20multiple%20regression%20analyses.%20All%20associations%20were%20controlled%20for%20age%2C%20gender%2C%20socioeconomic%20status%2C%20and%20dependent%20variables%20at%20baseline.%20Results%3A%20The%20consumption%20times%20of%20the%20different%20screen-based%20media%20were%20significantly%20related.%20Similarly%2C%20the%20different%20sleep-related%20problems%20showed%20significant%20interrelations.%20Most%20importantly%2C%20the%20analyses%20revealed%20significant%20associations%20between%20a%20high%20baseline%20consumption%20of%20computer%20and%20Internet%20with%20more%20problems%20at%20bedtime%2C%20as%20well%20as%20more%20daytime%20sleepiness%20at%20follow-up.%20Furthermore%2C%20baseline%20daytime%20sleepiness%20was%20associated%20with%20a%20higher%20consumption%20of%20TV%20or%20video%20at%20follow-up.%20Conclusions%3A%20These%20results%20indicate%20a%20mutual%20dependency%20of%20media%20consumption%20and%20sleep%20over%20time.%22%2C%22date%22%3A%222019%20Nov-Dec%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1080%5C%2F15402002.2018.1491851%22%2C%22ISSN%22%3A%221540-2010%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1080%5C%2F15402002.2018.1491851%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-07T07%3A01%3A31Z%22%7D%7D%2C%7B%22key%22%3A%22DYMDUAMP%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Poulain%20et%20al.%22%2C%22parsedDate%22%3A%222019-11%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EPoulain%2C%20Tanja%2C%20Juliane%20Ludwig%2C%20Andreas%20Hiemisch%2C%20Anja%20Hilbert%2C%20and%20Wieland%20Kiess.%20%26%23x201C%3BMedia%20Use%20of%20Mothers%2C%20Media%20Use%20of%20Children%2C%20and%20Parent%26%23×2013%3BChild%20Interaction%20Are%20Related%20to%20Behavioral%20Difficulties%20and%20Strengths%20of%20Children.%26%23x201D%3B%20%3Ci%3EInternational%20Journal%20of%20Environmental%20Research%20and%20Public%20Health%3C%5C%2Fi%3E%2016%2C%20no.%2023%20%28November%202019%29%3A%204651.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Fijerph16234651%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Fijerph16234651%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Media%20Use%20of%20Mothers%2C%20Media%20Use%20of%20Children%2C%20and%20Parent%5Cu2013Child%20Interaction%20Are%20Related%20to%20Behavioral%20Difficulties%20and%20Strengths%20of%20Children%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Juliane%22%2C%22lastName%22%3A%22Ludwig%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andreas%22%2C%22lastName%22%3A%22Hiemisch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anja%22%2C%22lastName%22%3A%22Hilbert%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%5D%2C%22abstractNote%22%3A%22The%20present%20study%20investigated%20the%20associations%20of%20media%20use%20of%20children%2C%20media%20use%20of%20mothers%2C%20and%20parent-child%20interactions%20with%20behavioral%20strengths%20and%20difficulties%20in%20children.%20Screen%20time%20of%20553%202-%20to%209-year-old%20children%20and%20their%20mothers%20were%20indicated%20by%20the%20daily%20durations%20of%20their%20TV%5C%2Fgames%20console%5C%2Fcomputer%5C%2Fmobile%20phone%20use.%20The%20amount%20of%20parent%26ndash%3Bchild%20interaction%20was%20indicated%20by%20the%20frequencies%20of%20shared%20activities%20at%20home.%20Behavioral%20strengths%20and%20difficulties%20of%20children%20were%20investigated%20using%20the%20Strengths%20and%20Difficulties%20Questionnaire.%20Children%20whose%20mothers%20reported%20high%20screen%20times%20%28%26gt%3B%5C%2F%3D%205%20h%5C%2Fday%29%20were%20significantly%20more%20likely%20to%20show%20high%20screen%20times%20%28%26gt%3B%5C%2F%3D%202%20h%5C%2Fday%29.%20High%20screen%20time%20of%20children%20was%20associated%20with%20more%20conduct%20problems%2C%20more%20symptoms%20of%20hyperactivity%5C%2Finattention%20and%20less%20prosocial%20behavior.%20High%20screen%20time%20of%20mothers%20was%20associated%20with%20emotional%20problems%2C%20conduct%20problems%2C%20and%20symptoms%20of%20hyperactivity%5C%2Finattention.%20In%20contrast%2C%20a%20higher%20frequency%20of%20parent%26ndash%3Bchild%20interactions%20was%20associated%20with%20fewer%20conduct%20problems%2C%20fewer%20peer-relationship%20problems%2C%20and%20more%20prosocial%20behavior%20of%20children.%20Children%20might%20use%20the%20media%20behavior%20of%20their%20mothers%20as%20a%20role%20model%20for%20their%20own%20media%20use.%20Furthermore%2C%20the%20findings%20suggest%20that%20media%20use%20of%20children%20and%20mothers%20and%20parent%26ndash%3Bchild%20interaction%20contribute%20independently%20to%20behavioral%20strengths%20and%20difficulties%20of%20children.%22%2C%22date%22%3A%222019-11%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.3390%5C%2Fijerph16234651%22%2C%22ISSN%22%3A%22%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.mdpi.com%5C%2F1660-4601%5C%2F16%5C%2F23%5C%2F4651%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-07T07%3A01%3A34Z%22%7D%7D%2C%7B%22key%22%3A%227D4H23HL%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Auhuber%20et%20al.%22%2C%22parsedDate%22%3A%222019-06-12%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EAuhuber%2C%20Lea%2C%20Mandy%20Vogel%2C%20Nico%20Grafe%2C%20Wieland%20Kiess%2C%20and%20Tanja%20Poulain.%20%26%23x201C%3BLeisure%20Activities%20of%20Healthy%20Children%20and%20Adolescents.%26%23x201D%3B%20%3Ci%3EInternational%20Journal%20of%20Environmental%20Research%20and%20Public%20Health%3C%5C%2Fi%3E%2016%2C%20no.%2012%20%28June%2012%2C%202019%29.%20%3Ca%20class%3D%27zp-ItemURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Fijerph16122078%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Fijerph16122078%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Leisure%20Activities%20of%20Healthy%20Children%20and%20Adolescents%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Lea%22%2C%22lastName%22%3A%22Auhuber%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Nico%22%2C%22lastName%22%3A%22Grafe%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%5D%2C%22abstractNote%22%3A%22The%20objective%20of%20the%20present%20study%20was%20to%20give%20a%20detailed%20overview%20on%20the%20leisure%20behavior%20of%20adolescents%20%28frequency%2C%20differences%20between%20gender%2C%20age%20groups%20and%20social%20class%2C%20time%20trends%2C%20and%20inter-relations%29.%20In%20total%2C%201449%2010-%20to%2018-year-old%20German%20adolescents%20were%20included%20in%20the%20study.%20Participants%20answered%20questionnaires%20about%20their%20media%20use%2C%20physical%20activity%2C%20outdoor%20time%2C%20engagement%20in%20choir%5C%2Forchestra%20and%20theater%5C%2Fdancing%2C%20social%20life%20and%20socio-economic%20status%20%28SES%29.%20The%20results%20revealed%20that%20girls%2C%20children%20with%20lower%20SES%20as%20well%20as%20older%20children%20reported%20to%20use%20screen-based%20media%20more%20often%20and%20that%20girls%2C%20older%20children%20and%20children%20with%20lower%20SES%20were%20less%20physically%20active.%20In%20addition%2C%20boys%20and%20children%20with%20lower%20SES%20engaged%20less%20frequently%20in%20choir%5C%2Forchestra%20and%20theater%5C%2Fdancing%2C%20while%20children%20with%20higher%20SES%20met%20their%20friends%20more%20often.%20The%20time%20trend%20analysis%20showed%20that%20mobile%20phone%20use%20increased%20drastically%20from%202011%20to%202017%2C%20while%20engagement%20in%20choir%5C%2Forchestra%20and%20theater%5C%2Fdancing%20decreased.%20Regarding%20the%20inter-relation%20between%20leisure%20activities%2C%20high%20screen%20times%20were%20significantly%20associated%20with%20less%20physical%20activity%20and%20less%20outdoor%20time.%20Physical%20activity%2C%20in%20contrast%2C%20was%20significantly%20related%20to%20better%20social%20life%20and%20more%20outdoor%20time.%20These%20findings%20highlight%20the%20growing%20importance%20of%20electronic%20media%20in%20adolescents%27%20lives%20and%20their%20tendency%20to%20displace%20other%20leisure%20activities.%22%2C%22date%22%3A%2212%20June%202019%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.3390%5C%2Fijerph16122078%22%2C%22ISSN%22%3A%221660-4601%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Fijerph16122078%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-07T07%3A01%3A55Z%22%7D%7D%2C%7B%22key%22%3A%2244BTJULX%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Poulain%20et%20al.%22%2C%22parsedDate%22%3A%222019%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EPoulain%2C%20Tanja%2C%20Mandy%20Vogel%2C%20Juliane%20Ludwig%2C%20Nico%20Grafe%2C%20Antje%20K%26%23xF6%3Brner%2C%20and%20Wieland%20Kiess.%20%26%23x201C%3BReciprocal%20Longitudinal%20Associations%20Between%20Adolescents%26%23×2019%3B%20Media%20Consumption%20and%20Psychological%20Health.%26%23x201D%3B%20%3Ci%3EAcademic%20Pediatrics%3C%5C%2Fi%3E%2019%2C%20no.%201%20%282019%29%3A%20109%26%23×2013%3B17.%20%3Ca%20class%3D%27zp-ItemURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.acap.2018.08.009%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.acap.2018.08.009%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Reciprocal%20Longitudinal%20Associations%20Between%20Adolescents%27%20Media%20Consumption%20and%20Psychological%20Health%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Juliane%22%2C%22lastName%22%3A%22Ludwig%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Nico%22%2C%22lastName%22%3A%22Grafe%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%5D%2C%22abstractNote%22%3A%22OBJECTIVE%3A%20This%20study%20investigated%20reciprocal%20longitudinal%20associations%20between%20media%20use%5C%2Fphysical%20activity%20and%20adolescents%27%20psychological%20health.%5CnMETHODS%3A%20Data%20were%20collected%20between%202011%20and%202017%20in%20the%20LIFE%20Child%20study%20in%20Germany.%20The%20sample%20included%20814%2010-%20to%2017-year-old%20adolescents.%20The%20participants%20provided%20information%20on%20their%20media%20use%20per%20day%20%28hours%20of%20television%5C%2Fvideo%2C%20computer%5C%2FInternet%2C%20and%20mobile%20phone%20use%29%2C%20physical%20activity%20%28frequency%20of%20organized%20and%20non-organized%20physical%20activity%20per%20week%29%2C%20behavioral%20difficulties%20%28emotional%20problems%2C%20conduct%20problems%2C%20hyperactivity%5C%2Finattention%2C%20peer%20relationship%20problems%29%2C%20and%20quality%20of%20life%20%28physical%20and%20psychological%20well-being%3B%20satisfaction%20with%20parents%2C%20peers%2C%20and%20school%29%20at%202%20time%20points%2012%20months%20apart.%20Multiple%20regressions%20were%20applied%20to%20analyze%20reciprocal%20longitudinal%20associations%20between%20media%20use%5C%2Fphysical%20activity%20and%20behavioral%20difficulties%5C%2Fquality%20of%20life.%5CnRESULTS%3A%20Frequent%20use%20of%20computers%5C%2FInternet%20at%20baseline%20was%20associated%20with%20an%20increase%20in%20internalizing%20behavioral%20difficulties%20%28emotional%20problems%20and%20peer%20relationship%20problems%29%20at%20follow-up.%20Additionally%2C%20a%20high%20frequency%20of%20computer%5C%2FInternet%20and%20mobile%20phone%20use%20was%20related%20to%20a%20decrease%20in%20psychological%20well-being%2C%20whereas%20a%20high%20frequency%20of%20organized%20physical%20activity%20was%20linked%20to%20improved%20physical%20well-being.%20The%20analyses%20also%20revealed%20a%20link%20between%20more%20behavioral%20difficulties%20at%20baseline%20and%20increased%20television%20consumption%20at%20follow-up.%5CnCONCLUSION%3A%20This%20study%20suggests%20mutual%20dependencies%20between%20electronic%20media%20use%20and%20psychological%20health%20over%20time.%22%2C%22date%22%3A%222019%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1016%5C%2Fj.acap.2018.08.009%22%2C%22ISSN%22%3A%221876-2867%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.acap.2018.08.009%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-07T07%3A01%3A31Z%22%7D%7D%2C%7B%22key%22%3A%22XYSSAYPY%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Poulain%20et%20al.%22%2C%22parsedDate%22%3A%222018-04%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EPoulain%2C%20Tanja%2C%20Thomas%20Peschel%2C%20Mandy%20Vogel%2C%20Anne%20Jurkutat%2C%20and%20Wieland%20Kiess.%20%26%23x201C%3BCross-Sectional%20and%20Longitudinal%20Associations%20of%20Screen%20Time%20and%20Physical%20Activity%20with%20School%20Performance%20at%20Different%20Types%20of%20Secondary%20School.%26%23x201D%3B%20%3Ci%3EBMC%20Public%20Health%3C%5C%2Fi%3E%2018%2C%20no.%201%20%28April%202018%29%3A%20563.%20%3Ca%20class%3D%27zp-ItemURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs12889-018-5489-3%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs12889-018-5489-3%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Cross-Sectional%20and%20Longitudinal%20Associations%20of%20Screen%20Time%20and%20Physical%20Activity%20with%20School%20Performance%20at%20Different%20Types%20of%20Secondary%20School%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Thomas%22%2C%22lastName%22%3A%22Peschel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anne%22%2C%22lastName%22%3A%22Jurkutat%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%5D%2C%22abstractNote%22%3A%22BACKGROUND%3A%20Previous%20studies%20have%20already%20reported%20associations%20of%20media%20consumption%20and%5C%2For%20physical%20activity%20with%20school%20achievement.%20However%2C%20longitudinal%20studies%20investigating%20independent%20effects%20of%20physical%20activity%20and%20media%20consumption%20on%20school%20performance%20are%20sparse.%20The%20present%20study%20fills%20this%20research%20gap%20and%2C%20furthermore%2C%20assesses%20relationships%20of%20the%20type%20of%20secondary%20school%20with%20media%20consumption%20and%20physical%20activity.%5CnMETHODS%3A%20The%20consumption%20of%20screen-based%20media%20%28TV%5C%2Fvideo%2C%20game%20console%2C%20PC%5C%2Finternet%2C%20and%20mobile%20phone%29%20and%20leisure%20physical%20activity%20%28organized%20and%20non-organized%29%20of%2010%20-%20to%2017-year%20old%20adolescents%20participating%20in%20the%20LIFE%20Child%20study%20in%20Germany%20were%20related%20to%20their%20school%20grades%20in%20two%20major%20school%20subjects%20%28Mathematics%20and%20German%29%20and%20in%20Physical%20Education.%20In%20addition%20to%20a%20cross-sectional%20analysis%20at%20baseline%20%28N%20%3D%20850%29%2C%20a%20longitudinal%20analysis%20%28N%20%3D%20512%29%20investigated%20the%20independent%20effects%20of%20these%20activities%20on%20the%20school%20grades%20achieved%2012%20months%20later.%20All%20associations%20were%20adjusted%20for%20age%2C%20gender%2C%20socio-economic%20status%2C%20year%20of%20data%20assessment%2C%20body-mass-index%2C%20and%20school%20grades%20at%20baseline.%20A%20further%20analysis%20investigated%20differences%20in%20the%20consumption%20of%20screen-based%20media%20and%20physical%20activity%20as%20a%20function%20of%20the%20type%20of%20secondary%20school%20%28highest%20vs.%20lower%20secondary%20school%29.%5CnRESULTS%3A%20Adolescents%20of%20lower%20secondary%20schools%20reported%20a%20significantly%20higher%20consumption%20of%20TV%5C%2Fvideo%20and%20game%20consoles%20than%20adolescents%20attending%20the%20highest%20secondary%20school.%20Independently%20of%20the%20type%20of%20school%2C%20a%20better%20school%20performance%20in%20Mathematics%20was%20predicted%20by%20a%20lower%20consumption%20of%20computers%5C%2Finternet%2C%20and%20a%20better%20performance%20in%20Physical%20Education%20was%20predicted%20by%20a%20lower%20consumption%20of%20TV%5C%2Fvideo%20and%20a%20higher%20frequency%20of%20non-organized%20physical%20activity.%20However%2C%20the%20association%20between%20non-organized%20physical%20activity%20and%20subsequent%20grades%20in%20Physical%20Education%20was%20significant%20in%20girls%20only.%5CnCONCLUSION%3A%20The%20present%20results%20suggest%20that%20media%20consumption%20has%20a%20negative%20effect%20on%20school%20achievement%2C%20whereas%20physical%20activity%20has%20a%20positive%20effect%2C%20which%2C%20however%2C%20is%20restricted%20to%20the%20subject%20Physical%20Education.%20Future%20studies%20might%20explore%20the%20relationship%20between%20media%20consumption%20and%20school%20career%2C%20for%20example%2C%20the%20choice%20or%20change%20of%20the%20secondary%20school%20type%2C%20in%20more%20detail.%22%2C%22date%22%3A%22April%2C%202018%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1186%5C%2Fs12889-018-5489-3%22%2C%22ISSN%22%3A%221471-2458%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs12889-018-5489-3%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-07T07%3A01%3A32Z%22%7D%7D%2C%7B%22key%22%3A%22XT7PMZUK%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Poulain%20et%20al.%22%2C%22parsedDate%22%3A%222018-04%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EPoulain%2C%20Tanja%2C%20Mandy%20Vogel%2C%20Madlen%20Neef%2C%20Franziska%20Abicht%2C%20Anja%20Hilbert%2C%20Jon%20Genuneit%2C%20Antje%20K%26%23xF6%3Brner%2C%20and%20Wieland%20Kiess.%20%26%23x201C%3BReciprocal%20Associations%20Between%20Electronic%20Media%20Use%20and%20Behavioral%20Difficulties%20in%20Preschoolers.%26%23x201D%3B%20%3Ci%3EInternational%20Journal%20of%20Environmental%20Research%20and%20Public%20Health%3C%5C%2Fi%3E%2015%2C%20no.%204%20%28April%202018%29%3A%20814.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Fijerph15040814%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Fijerph15040814%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Reciprocal%20Associations%20Between%20Electronic%20Media%20Use%20and%20Behavioral%20Difficulties%20in%20Preschoolers%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Madlen%22%2C%22lastName%22%3A%22Neef%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Franziska%22%2C%22lastName%22%3A%22Abicht%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anja%22%2C%22lastName%22%3A%22Hilbert%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jon%22%2C%22lastName%22%3A%22Genuneit%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%5D%2C%22abstractNote%22%3A%22The%20use%20of%20electronic%20media%20has%20increased%20substantially%20and%20is%20already%20observable%20in%20young%20children.%20The%20present%20study%20explored%20associations%20of%20preschoolers%5Cu2019%20use%20of%20electronic%20media%20with%20age%2C%20gender%2C%20and%20socio-economic%20status%2C%20investigated%20time%20trends%2C%20and%20examined%20reciprocal%20longitudinal%20relations%20between%20children%5Cu2019s%20use%20of%20electronic%20media%20and%20their%20behavioral%20difficulties.%20The%20study%20participants%20included%20527%20German%20two-%20to%20six-year-old%20children%20whose%20parents%20had%20provided%20information%20on%20their%20use%20of%20electronic%20media%20and%20their%20behavioral%20difficulties%20at%20two%20time%20points%2C%20with%20approximately%2012%20months%20between%20baseline%20and%20follow-up.%20The%20analyses%20revealed%20that%20older%20vs.%20younger%20children%2C%20as%20well%20as%20children%20from%20families%20with%20a%20lower%20vs.%20higher%20socio-economic%20status%2C%20were%20more%20often%20reported%20to%20use%20electronic%20media.%20Furthermore%2C%20the%20usage%20of%20mobile%20phones%20increased%20significantly%20between%202011%20and%202016.%20Most%20interestingly%2C%20baseline%20usage%20of%20computer%5C%2FInternet%20predicted%20more%20emotional%20and%20conduct%20problems%20at%20follow-up%2C%20and%20baseline%20usage%20of%20mobile%20phones%20was%20associated%20with%20more%20conduct%20problems%20and%20hyperactivity%20or%20inattention%20at%20follow-up.%20Peer%20relationship%20problems%20at%20baseline%2C%20on%20the%20other%20hand%2C%20increased%20the%20likelihood%20of%20using%20computer%5C%2FInternet%20and%20mobile%20phones%20at%20follow-up.%20The%20findings%20indicate%20that%20preschoolers%5Cu2019%20use%20of%20electronic%20media%2C%20especially%20newer%20media%20such%20as%20computer%5C%2FInternet%20and%20mobile%20phones%2C%20and%20their%20behavioral%20difficulties%20are%20mutually%20related%20over%20time.%22%2C%22date%22%3A%222018-04%22%2C%22language%22%3A%22English%22%2C%22DOI%22%3A%2210.3390%5C%2Fijerph15040814%22%2C%22ISSN%22%3A%221661-7827%22%2C%22url%22%3A%22http%3A%5C%2F%5C%2Fsearch.proquest.com%5C%2Fdocview%5C%2F2041105240%5C%2Fabstract%5C%2F6A989AE9C3D3426FPQ%5C%2F1%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-07T07%3A01%3A31Z%22%7D%7D%5D%7D
Poulain, Tanja, Cornelia Hilbert, Annelie Grundmann, and Wieland Kiess. “Associations between Media Use at Bedtime and Sleep: A Cross-Sectional Analysis on Differences between Girls and Boys.” Frontiers in Psychology 15 (July 12, 2024). https://doi.org/10.3389/fpsyg.2024.1290935.
Poulain, Tanja, Christof Meigen, Wieland Kiess, and Mandy Vogel. “Media Regulation Strategies in Parents of 4- to 16-Year-Old Children and Adolescents: A Cross-Sectional Study.” BMC Public Health 23, no. 1 (February 21, 2023): 371. https://doi.org/10.1186/s12889-023-15221-w.
Kliesener, Tobias, Christof Meigen, Wieland Kiess, and Tanja Poulain. “Associations Between Problematic Smartphone Use and Behavioural Difficulties, Quality of Life, and School Performance Among Children and Adolescents.” BMC Psychiatry 22, no. 1 (March 2022): 1–12. https://doi.org/10.1186/s12888-022-03815-4.
Poulain, Tanja, Mandy Vogel, Tobias Kliesener, and Wieland Kiess. “Associations Between Changes in Behavioral Difficulties and Levels of Problematic Smartphone Use in Adolescents Over a 1-Year Period.” European Child & Adolescent Psychiatry online ahead of print (September 2021). https://doi.org/10.1007/s00787-021-01874-8.
Schwarzer, Clarissa, Nico Grafe, Andreas Hiemisch, Wieland Kiess, and Tanja Poulain. “Associations of Media Use and Early Childhood Development: Cross-Sectional Findings from the Life Child Study.” Pediatric Research online ahead of print (March 2021). https://doi.org/10.1038/s41390-021-01433-6.
Poulain, Tanja, Christof Meigen, Carolin Sobek, Peggy Ober, Ulrike Igel, Antje Körner, Wieland Kiess, and Mandy Vogel. “Loss of Childcare and Classroom Teaching During the Covid-19-Related Lockdown in Spring 2020: A Longitudinal Study on Consequences on Leisure Behavior and Schoolwork at Home.” PloS One 16, no. 3 (March 2021): e0247949. https://doi.org/10.1371/journal.pone.0247949.
Vogel, Mandy, Christof Meigen, Carolin Sobek, Peggy Ober, Ulrike Igel, Antje Körner, Wieland Kiess, and Tanja Poulain. “Well-Being and Covid-19-Related Worries of German Children and Adolescents: A Longitudinal Study from Pre-Covid to the End of Lockdown in Spring 2020.” JCPP Advances 1, no. 1 (March 2021): e12004. https://doi.org/10.1111/jcv2.12004.
Poulain, Tanja, Carolin Sobek, Juliane Ludwig, Ulrike Igel, Gesine Grande, Verena Ott, Wieland Kiess, Antje Körner, and Mandy Vogel. “Associations of Green Spaces and Streets in the Living Environment with Outdoor Activity, Media Use, Overweight/Obesity and Emotional Wellbeing in Children and Adolescents.” International Journal of Environmental Research and Public Health 17, no. 17 (August 2020): 6321. https://doi.org/10.3390/ijerph17176321.
Poulain, Tanja, Mandy Vogel, Christof Meigen, Ulrike Spielau, Andreas Hiemisch, and Wieland Kiess. “Parent-Child Agreement in Different Domains of Child Behavior and Health.” PloS One 15, no. 4 (2020): e0231462. https://doi.org/10.1371/journal.pone.0231462.
Poulain, Tanja, Mandy Vogel, Theresa Buzek, Jon Genuneit, Andreas Hiemisch, and Wieland Kiess. “Reciprocal Longitudinal Associations Between Adolescents’ Media Consumption and Sleep.” Behavioral Sleep Medicine 17, no. 6 (December 2019): 763–77. https://doi.org/10.1080/15402002.2018.1491851.
Poulain, Tanja, Juliane Ludwig, Andreas Hiemisch, Anja Hilbert, and Wieland Kiess. “Media Use of Mothers, Media Use of Children, and Parent–Child Interaction Are Related to Behavioral Difficulties and Strengths of Children.” International Journal of Environmental Research and Public Health 16, no. 23 (November 2019): 4651. https://doi.org/10.3390/ijerph16234651.
Auhuber, Lea, Mandy Vogel, Nico Grafe, Wieland Kiess, and Tanja Poulain. “Leisure Activities of Healthy Children and Adolescents.” International Journal of Environmental Research and Public Health 16, no. 12 (June 12, 2019). https://doi.org/10.3390/ijerph16122078.
Poulain, Tanja, Mandy Vogel, Juliane Ludwig, Nico Grafe, Antje Körner, and Wieland Kiess. “Reciprocal Longitudinal Associations Between Adolescents’ Media Consumption and Psychological Health.” Academic Pediatrics 19, no. 1 (2019): 109–17. https://doi.org/10.1016/j.acap.2018.08.009.
Poulain, Tanja, Thomas Peschel, Mandy Vogel, Anne Jurkutat, and Wieland Kiess. “Cross-Sectional and Longitudinal Associations of Screen Time and Physical Activity with School Performance at Different Types of Secondary School.” BMC Public Health 18, no. 1 (April 2018): 563. https://doi.org/10.1186/s12889-018-5489-3.
Poulain, Tanja, Mandy Vogel, Madlen Neef, Franziska Abicht, Anja Hilbert, Jon Genuneit, Antje Körner, and Wieland Kiess. “Reciprocal Associations Between Electronic Media Use and Behavioral Difficulties in Preschoolers.” International Journal of Environmental Research and Public Health 15, no. 4 (April 2018): 814. https://doi.org/10.3390/ijerph15040814.
2390247
T52N9QLZ
SDS
1
chicago-fullnote-bibliography
50
date
desc
1
1
6748
https://home.uni-leipzig.de/lifechild/wp-content/plugins/zotpress/
%7B%22status%22%3A%22success%22%2C%22updateneeded%22%3Afalse%2C%22instance%22%3Afalse%2C%22meta%22%3A%7B%22request_last%22%3A0%2C%22request_next%22%3A0%2C%22used_cache%22%3Atrue%7D%2C%22data%22%3A%5B%7B%22key%22%3A%22YYGNEXF2%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22lastModifiedByUser%22%3A%7B%22id%22%3A5423163%2C%22username%22%3A%22erossi19%22%2C%22name%22%3A%22%22%2C%22links%22%3A%7B%22alternate%22%3A%7B%22href%22%3A%22https%3A%5C%2F%5C%2Fwww.zotero.org%5C%2Ferossi19%22%2C%22type%22%3A%22text%5C%2Fhtml%22%7D%7D%7D%2C%22creatorSummary%22%3A%22Grosse-Thie%20et%20al.%22%2C%22parsedDate%22%3A%222024-07-19%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EGrosse-Thie%2C%20Charlotte%2C%20Mandy%20Vogel%2C%20Ronny%20Baber%2C%20Uta%20Ceglarek%2C%20and%20Wieland%20Kiess.%20%26%23x201C%3BBilirubin%20Levels%20in%20Infancy%20and%20Their%20Associations%20with%20Body%20Weight%2C%20Levels%20of%20Iron-Related%20Parameters%20and%20Steroid%20Hormone%20Levels.%26%23x201D%3B%20%3Ci%3EMetabolites%3C%5C%2Fi%3E%2014%2C%20no.%207%20%28July%2019%2C%202024%29%3A%20393.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Fmetabo14070393%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Fmetabo14070393%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Bilirubin%20Levels%20in%20Infancy%20and%20Their%20Associations%20with%20Body%20Weight%2C%20Levels%20of%20Iron-Related%20Parameters%20and%20Steroid%20Hormone%20Levels%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Charlotte%22%2C%22lastName%22%3A%22Grosse-Thie%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ronny%22%2C%22lastName%22%3A%22Baber%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Uta%22%2C%22lastName%22%3A%22Ceglarek%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%5D%2C%22abstractNote%22%3A%22It%20is%20assumed%20that%20bilirubin%20is%20hormonally%20regulated%20and%20influences%20weight%20development%20by%20preventing%20weight%20gain.%20However%2C%20studies%20in%20healthy%20infants%20are%20limited.%20The%20present%20study%20established%20reference%20values%20for%20bilirubin%20and%20investigated%20whether%20bilirubin%20levels%20are%20significantly%20associated%20with%20body%20weight%2C%20levels%20of%20ferritin%20and%20transferrin%20as%20well%20as%20steroid%20hormone%20levels%20in%20a%20study%20population%20of%20three-%20and%20six-month-old%20healthy%20infants.%20Data%20from%20a%20total%20of%20411%20study%20visits%20from%20the%20LIFE%20Child%20study%20%28Leipzig%2C%20Germany%29%20were%20analyzed.%20Associations%20were%20examined%20using%20linear%20regression%20analyses.%20Besides%20laboratory%20parameters%2C%20anthropometric%20data%20were%20gathered.%20We%20found%20statistically%20significant%20associations%20between%20body%20weight%20and%20bilirubin%20levels.%20In%20girls%2C%20we%20observed%20additional%20associations%20between%20bilirubin%20levels%20and%20both%20ferritin%20and%20transferrin%20concentrations%20at%20three%20months%20of%20age.%20At%20six%20months%2C%20steroid%20hormone%20levels%20were%20significantly%20associated%20with%20concentrations%20of%20total%20and%20indirect%20bilirubin%2C%20with%20effects%20differing%20by%20sex.%20Our%20study%20thus%20confirms%20associations%20already%20reported%20from%20animal%20studies%20and%20studies%20in%20adult%20populations.%20Furthermore%2C%20we%20showed%20that%20these%20associations%20already%20exist%20in%20the%20first%20year%20of%20life%2C%20are%20influenced%20by%20sex%20and%20age%20and%2C%20further%2C%20depend%20on%20the%20bilirubin%20type.%20Our%20results%20provide%20reference%20values%20for%20bilirubin%20and%20assist%2C%20therefore%2C%20in%20interpreting%20bilirubin%20levels%20in%20infancy.%22%2C%22date%22%3A%222024-07-19%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.3390%5C%2Fmetabo14070393%22%2C%22ISSN%22%3A%222218-1989%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.mdpi.com%5C%2F2218-1989%5C%2F14%5C%2F7%5C%2F393%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222024-08-27T12%3A22%3A08Z%22%7D%7D%2C%7B%22key%22%3A%225GVVR5GN%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Prenzel%20et%20al.%22%2C%22parsedDate%22%3A%222024-07-08%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EPrenzel%2C%20Freerk%2C%20Thorsten%20Kaiser%2C%20Anja%20Willenberg%2C%20Maike%20vom%20Hove%2C%20Gunter%20Flemming%2C%20Lars%20Fischer%2C%20J%26%23xFC%3Brgen%20Kratzsch%2C%20Wieland%20Kiess%2C%20and%20Mandy%20Vogel.%20%26%23x201C%3BReference%20Intervals%20and%20Percentiles%20for%20Soluble%20Transferrin%20Receptor%20and%20STfR%5C%2FLog%20Ferritin%20Index%20in%20Healthy%20Children%20and%20Adolescents.%26%23x201D%3B%20%3Ci%3EClinical%20Chemistry%20and%20Laboratory%20Medicine%20%28CCLM%29%3C%5C%2Fi%3E%2C%20July%208%2C%202024.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1515%5C%2Fcclm-2024-0369%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1515%5C%2Fcclm-2024-0369%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Reference%20intervals%20and%20percentiles%20for%20soluble%20transferrin%20receptor%20and%20sTfR%5C%2Flog%20ferritin%20index%20in%20healthy%20children%20and%20adolescents%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Freerk%22%2C%22lastName%22%3A%22Prenzel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Thorsten%22%2C%22lastName%22%3A%22Kaiser%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anja%22%2C%22lastName%22%3A%22Willenberg%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Maike%20vom%22%2C%22lastName%22%3A%22Hove%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Gunter%22%2C%22lastName%22%3A%22Flemming%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Lars%22%2C%22lastName%22%3A%22Fischer%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J%5Cu00fcrgen%22%2C%22lastName%22%3A%22Kratzsch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%5D%2C%22abstractNote%22%3A%22Objectives%20Soluble%20transferrin%20receptor%20%28sTfR%29%20is%20a%20marker%20of%20both%20erythropoiesis%20and%20iron%20status%20and%20is%20considered%20useful%20for%20detecting%20iron%20deficiency%2C%20especially%20in%20inflammatory%20conditions%2C%20but%20reference%20intervals%20covering%20the%20entire%20pediatric%20age%20spectrum%20are%20lacking.%20Methods%20We%20studied%201%2C064%20%2848.5%5Cu202f%25%20female%29%20healthy%20children%20of%20the%20entire%20pediatric%20age%20spectrum%20to%20determine%20reference%20values%20and%20percentiles%20for%20sTfR%20and%20the%20ratio%20of%20sTfR%20to%20log-ferritin%20%28sTfR-F%20index%29%20using%20a%20standard%20immunoturbidimetric%20assay.%20Results%20Soluble%20TfR%20levels%20were%20highly%20age-specific%2C%20with%20a%20peak%20in%20infancy%20and%20a%20decline%20in%20adulthood%2C%20whereas%20the%20sTfR-F%20index%20was%20a%20rather%20constant%20parameter.%20There%20were%20positive%20linear%20relationships%20for%20sTfR%20with%20hemoglobin%20%28Hb%29%20%28p%3D0.008%29%20and%20transferrin%20%28females%20p%26lt%3B0.001%3B%20males%20p%3D0.003%29.%20A%5Cu00a0negative%20association%20was%20observed%20between%20sTfR%20and%20ferritin%20in%20females%20%28p%26lt%3B0.0001%29%20and%20for%20transferrin%20saturation%20and%20mean%20corpuscular%20volume%20%28MCV%29%20in%20both%20sexes%20%28both%20p%26lt%3B0.0001%29.%20We%20found%20a%20positive%20relationship%20between%20sTfR%20and%20body%20height%2C%20body%20mass%20index%20%28BMI%29%20and%20inflammatory%20markers%20%28CrP%20p%26lt%3B0.0001%3B%20WBC%20p%3D0.0172%29%2C%20while%20sTfR-F%20index%20was%20not%20affected%20by%20inflammation.%20Conclusions%20Soluble%20TfR%20values%20appear%20to%20reflect%20the%20activity%20of%20infant%20erythropoiesis%20and%20to%20be%20modulated%20by%20inflammation%20and%20iron%20deficiency%20even%20in%20a%20healthy%20cohort.%22%2C%22date%22%3A%222024-07-08%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1515%5C%2Fcclm-2024-0369%22%2C%22ISSN%22%3A%221437-4331%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.degruyter.com%5C%2Fdocument%5C%2Fdoi%5C%2F10.1515%5C%2Fcclm-2024-0369%5C%2Fhtml%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222024-11-14T13%3A48%3A49Z%22%7D%7D%2C%7B%22key%22%3A%22K5XMVMIN%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Fechner%20et%20al.%22%2C%22parsedDate%22%3A%222024-06-15%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EFechner%2C%20Anna%2C%20Anja%20Willenberg%2C%20Niels%20Ziegelasch%2C%20Andreas%20Merkenschlager%2C%20Wieland%20Kiess%2C%20and%20Mandy%20Vogel.%20%26%23x201C%3BCreatine%20Kinase%20Serum%20Levels%20in%20Children%20Revisited%3A%20New%20Reference%20Intervals%20from%20a%20Large%20Cohort%20of%20Healthy%20Children%20and%20Adolescents.%26%23x201D%3B%20%3Ci%3EClinica%20Chimica%20Acta%3C%5C%2Fi%3E%20560%20%28June%2015%2C%202024%29%3A%20119726.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.cca.2024.119726%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.cca.2024.119726%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Creatine%20kinase%20serum%20levels%20in%20children%20revisited%3A%20New%20reference%20intervals%20from%20a%20large%20cohort%20of%20healthy%20children%20and%20adolescents%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anna%22%2C%22lastName%22%3A%22Fechner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anja%22%2C%22lastName%22%3A%22Willenberg%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Niels%22%2C%22lastName%22%3A%22Ziegelasch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andreas%22%2C%22lastName%22%3A%22Merkenschlager%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%5D%2C%22abstractNote%22%3A%22Background%5CnCreatine%20Kinase%20%28CK%29%20has%20become%20increasingly%20important%20in%20pediatrics%20as%20a%20commonly%20used%20laboratory%20screening%20parameter%20for%20neuromuscular%20diseases.%20Recent%20research%20suggests%20that%20hyperCKemia%20in%20children%20is%20not%20always%20associated%20with%20pathology%20and%20can%20occur%20due%20to%20several%20reasons.%20Little%20is%20known%20of%20various%20clinical%20factors%20that%20may%20influence%20CK%20throughout%20child%20development.%5CnObjective%5CnThis%20study%20aimed%20to%20establish%20reliable%20age-%20and%20sex-specific%20reference%20ranges%20for%20serum%20CK%20levels%20in%20healthy%20infants%2C%20children%2C%20and%20adolescents.%20In%20addition%2C%20the%20effect%20of%20puberty%2C%20oral%20contraceptive%20%28OC%29%20use%20as%20well%20as%20steroid%20hormones%20on%20CK%20was%20examined.%5CnMaterials%20and%20methods%5CnThe%20data%20was%20collected%20from%20subjects%20of%20the%20longitudinal%20population-based%20%5Cu201cLIFE%20Child%5Cu201d-cohort%20between%202011%20and%202016%20in%20Leipzig%2C%20Germany.%205238%20blood%20samples%20of%202707%20healthy%20children%2C%20aged%20between%200.14%5Cu00a0months%20and%2018%5Cu00a0years%2C%20were%20analyzed.%5CnResults%5CnSerum%20CK%20levels%20raised%20during%20the%20first%20year%20of%20life%2C%20peaking%20shortly%20after%20age%20one%20%28P50girls%5Cu00a0%3D%5Cu00a02.7%20%5Cu00b5kat%5C%2FL%2C%20P50boys%5Cu00a0%3D%5Cu00a02.90%20%5Cu00b5kat%5C%2FL%29.%20There%20was%20a%20pronounced%20difference%20in%20the%2097.5th%20percentile%20between%20boys%20and%20girls%20during%20adolescence%20with%20its%20maximum%20at%20age%2018%20%28P97.5girls%5Cu00a0%3D%5Cu00a05.74%20%5Cu00b5kat%5C%2FL%2C%20P97.5boys%3D%2014.48%20%5Cu00b5kat%5C%2FL%29.%20Also%2C%20mean%20CK%20serum%20levels%20were%20significantly%20higher%20in%20boys%20%28bboys%5Cu00a0%3D%5Cu00a00.29%2C%20pboys%5Cu00a0%3C%5Cu00a00.001%29.%20Intake%20of%20oral%20contraceptives%20%28OC%29%2C%20extreme%20underweight%2C%20underweight%20and%20obesity%20revealed%20a%20significant%20inverse%20correlation%20with%20CK%20serum%20levels.%5CnConclusion%5CnAge%2C%20sex%2C%20OC%20intake%20and%20weight%20status%20affect%20serum%20CK%20levels%2C%20particularly%20during%20infancy%20and%20puberty.%20We%20recommend%20the%20use%20of%20age-%20and%20sex-specific%20reference%20values%20for%20CK%20serum%20levels%20to%20assess%20the%20clinical%20relevance%20of%20measurements.%22%2C%22date%22%3A%222024-06-15%22%2C%22language%22%3A%22%22%2C%22DOI%22%3A%2210.1016%5C%2Fj.cca.2024.119726%22%2C%22ISSN%22%3A%220009-8981%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.sciencedirect.com%5C%2Fscience%5C%2Farticle%5C%2Fpii%5C%2FS0009898124019788%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222024-06-04T05%3A31%3A27Z%22%7D%7D%2C%7B%22key%22%3A%22W8FWC32V%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Ravi%20Teja%20et%20al.%22%2C%22parsedDate%22%3A%222024-05-15%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3ERavi%20Teja%2C%20Kasagani%20Venkata%2C%20Bhanu%20Malhotra%2C%20Mandy%20Vogel%2C%20Raman%20Kumar%20Marwaha%2C%20Arun%20Aggarwal%2C%20Rimesh%20Pal%2C%20Liza%20Das%2C%20et%20al.%20%26%23x201C%3BNormative%20Data%20for%20Insulin-like%20Growth%20Factor-1%20%28IGF-1%29%20in%20Healthy%20Children%20and%20Adolescents%20from%20India.%26%23x201D%3B%20%3Ci%3EThe%20Journal%20of%20Clinical%20Endocrinology%20and%20Metabolism%3C%5C%2Fi%3E%2C%20May%2015%2C%202024%2C%20dgae340.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F2024061217375967200%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F2024061217375967200%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Normative%20data%20for%20insulin-like%20growth%20factor-1%20%28IGF-1%29%20in%20healthy%20children%20and%20adolescents%20from%20India%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Kasagani%20Venkata%22%2C%22lastName%22%3A%22Ravi%20Teja%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Bhanu%22%2C%22lastName%22%3A%22Malhotra%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Raman%20Kumar%22%2C%22lastName%22%3A%22Marwaha%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Arun%22%2C%22lastName%22%3A%22Aggarwal%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Rimesh%22%2C%22lastName%22%3A%22Pal%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Liza%22%2C%22lastName%22%3A%22Das%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Naresh%22%2C%22lastName%22%3A%22Sachdeva%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Nagita%22%2C%22lastName%22%3A%22Devi%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Dipika%22%2C%22lastName%22%3A%22Bansal%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ashu%22%2C%22lastName%22%3A%22Rastogi%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Sadhna%22%2C%22lastName%22%3A%22Sharma%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Dewan%22%2C%22lastName%22%3A%22Gajinder%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Sanjay%20Kumar%22%2C%22lastName%22%3A%22Bhadada%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jayaditya%22%2C%22lastName%22%3A%22Ghosh%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Phillip%20J.%22%2C%22lastName%22%3A%22Monaghan%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22M%5Cu00e1rta%22%2C%22lastName%22%3A%22Korbonits%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Pinaki%22%2C%22lastName%22%3A%22Dutta%22%7D%5D%2C%22abstractNote%22%3A%22BACKGROUND%3A%20Serum%20IGF-1%20is%20an%20important%20biochemical%20tool%20to%20diagnose%20and%20monitor%20GH-related%20disorders.%20However%2C%20ethnic-specific%20Indian%20data%20following%20consensus%20criteria%20for%20the%20establishment%20of%20normative%20data%2C%20are%20not%20available.%20Our%20objective%20was%20to%20generate%20chronological%20age%20%28CA%29-%2C%20bone%20age%20%28BA%29-%20and%20Tanner%20stage-specific%20normative%20data%20for%20IGF-1%20in%20healthy%20Indian%20children%20and%20adolescents.%5CnMETHODS%3A%20A%20cross-sectional%20epidemiological%20study%20was%20conducted%20in%20schools%20and%20the%20community%2C%20which%20enrolled%20apparently%20healthy%20children%20and%20adolescents%20with%20robust%20exclusion%20criteria.%20The%20outcome%20measure%20was%20serum%20IGF-1%20assessed%20using%20an%20electro-chemiluminescence%20immunoassay%20%28ECLIA%29.%20The%202.5th%2C%205th%2C%2010th%2C%2025th%2C%2050th%20%28median%29%2C%2075th%2C%2090th%2C%2095th%2C%20and%2097.5th%20centiles%20for%20IGF-1%20were%20estimated%20using%20generalized%20additive%20models.%5CnRESULTS%3A%20We%20recruited%202226%20apparently%20healthy%20participants%20and%20following%20exclusion%2C%201948%20%281006%20boys%2C%20942%20girls%29%20were%20included%20in%20the%20final%20analysis.%20Girls%20had%20median%20IGF-1%20peak%20at%20CA%20of%2013%20years%20%28321.7%5Cu2005ng%5C%2FmL%29%2C%20BA%20of%2014%20years%20%28350.2%5Cu2005ng%5C%2FmL%29%20and%20Tanner%20stage%20IV%20%28345%5Cu2005ng%5C%2FmL%29%2C%20while%20boys%20had%20median%20IGF-1%20peak%20at%20CA%20of%2015%20years%20%28318.9%5Cu2005ng%5C%2FmL%29%20BA%20of%2015%20years%20%28340.6%5Cu2005ng%5C%2FmL%29%20and%20Tanner%20stage%20III%20%28304.8%5Cu2005ng%5C%2FmL%29.%20Girls%20had%20earlier%20rise%2C%20peak%20and%20higher%20IGF-1%20values.%20The%20reference%20interval%20%282.5th-97.5th%20percentile%29%20was%20broader%20during%20peri-pubertal%20ages%2C%20indicating%20a%20higher%20physiological%20variability.%5CnCONCLUSION%3A%20This%20study%20provides%20ethnicity-specific%20normative%20data%20on%20serum%20IGF-1%20and%20will%20improve%20the%20diagnostic%20utility%20of%20IGF-1%20in%20the%20evaluation%20and%20management%20of%20growth%20disorders%20in%20Indian%20children%20and%20adolescents.%22%2C%22date%22%3A%222024-05-15%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%222024061217375967200%22%2C%22ISSN%22%3A%221945-7197%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222024-08-27T12%3A34%3A44Z%22%7D%7D%2C%7B%22key%22%3A%22HHMBIJDL%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Wilpert%20et%20al.%22%2C%22parsedDate%22%3A%222024-01%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EWilpert%2C%20Nina-Maria%2C%20Roma%20Thamm%2C%20Michael%20Thamm%2C%20J%26%23xFC%3Brgen%20Kratzsch%2C%20Dominik%20Seelow%2C%20Mandy%20Vogel%2C%20Heiko%20Krude%2C%20and%20Markus%20Schuelke.%20%26%23x201C%3BNormal%20Values%20for%20the%20FT3%5C%2FFT4%20Ratio%3A%20Centile%20Charts%20%280%26%23×2013%3B29%20Years%29%20and%20Their%20Application%20for%20the%20Differential%20Diagnosis%20of%20Children%20with%20Developmental%20Delay.%26%23x201D%3B%20%3Ci%3EInternational%20Journal%20of%20Molecular%20Sciences%3C%5C%2Fi%3E%2025%2C%20no.%2016%20%28January%202024%29%3A%208585.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Fijms25168585%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Fijms25168585%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Normal%20Values%20for%20the%20fT3%5C%2FfT4%20Ratio%3A%20Centile%20Charts%20%280%5Cu201329%20Years%29%20and%20Their%20Application%20for%20the%20Differential%20Diagnosis%20of%20Children%20with%20Developmental%20Delay%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Nina-Maria%22%2C%22lastName%22%3A%22Wilpert%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Roma%22%2C%22lastName%22%3A%22Thamm%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Michael%22%2C%22lastName%22%3A%22Thamm%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J%5Cu00fcrgen%22%2C%22lastName%22%3A%22Kratzsch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Dominik%22%2C%22lastName%22%3A%22Seelow%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Heiko%22%2C%22lastName%22%3A%22Krude%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Markus%22%2C%22lastName%22%3A%22Schuelke%22%7D%5D%2C%22abstractNote%22%3A%22Primary%20congenital%20hypothyroidism%20is%20easily%20diagnosed%20on%20the%20basis%20of%20elevated%20plasma%20levels%20of%20thyroid-stimulating%20hormone%20%28TSH%29.%20In%20contrast%2C%20in%20the%20rare%20disorders%20of%20thyroid%20hormone%20resistance%2C%20TSH%20and%2C%20in%20mild%20cases%2C%20also%20thyroid%20hormone%20levels%20are%20within%20the%20normal%20range.%20Thyroid%20hormone%20resistance%20is%20caused%20by%20defects%20in%20hormone%20metabolism%2C%20transport%2C%20or%20receptor%20activation%20and%20can%20have%20the%20same%20serious%20consequences%20for%20child%20development%20as%20congenital%20hypothyroidism.%20A%20total%20of%20n%20%3D%2023%2C522%20data%20points%20from%20a%20large%20cohort%20of%20children%20and%20young%20adults%20were%20used%20to%20generate%20normal%20values%20and%20sex-specific%20percentiles%20for%20the%20ratio%20of%20free%20triiodothyronine%20%28T3%29%20to%20free%20thyroxine%20%28T4%29%2C%20the%20fT3%5C%2FfT4%20ratio.%20The%20aim%20was%20to%20determine%20whether%20individuals%20with%20developmental%20delay%20and%20genetically%20confirmed%20thyroid%20hormone%20resistance%2C%20carrying%20defects%20in%20Monocarboxylate%20Transporter%208%20%28MCT8%29%2C%20Thyroid%20Hormone%20Receptor%20alpha%20%28THR%5Cu03b1%29%2C%20and%20Selenocysteine%20Insertion%20Sequence-Binding%20Protein%202%20%28SECISBP2%29%2C%20had%20abnormal%20fT3%5C%2FfT4%20ratios.%20Indeed%2C%20we%20were%20able%20to%20demonstrate%20a%20clear%20separation%20of%20patient%20values%20for%20the%20fT3%5C%2FfT4%20ratio%20from%20normal%20and%20pathological%20controls%20%28e.g.%2C%20children%20with%20severe%20cerebral%20palsy%29.%20We%20therefore%20recommend%20using%20the%20fT3%5C%2FfT4%20ratio%20as%20a%20readily%20available%20screening%20parameter%20in%20children%20with%20developmental%20delay%20for%20the%20identification%20of%20thyroid%20hormone%20resistance%20syndromes.%20The%20fT3%5C%2FfT4%20ratio%20can%20be%20easily%20plotted%20on%20centile%20charts%20using%20our%20free%20online%20tool%2C%20which%20accepts%20various%20SI%20and%20non-SI%20units%20for%20fT3%2C%20fT4%2C%20and%20TSH.%22%2C%22date%22%3A%222024%5C%2F1%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.3390%5C%2Fijms25168585%22%2C%22ISSN%22%3A%221422-0067%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.mdpi.com%5C%2F1422-0067%5C%2F25%5C%2F16%5C%2F8585%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222024-08-13T15%3A36%3A37Z%22%7D%7D%2C%7B%22key%22%3A%22V6UXU4V3%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Ridefelt%20et%20al.%22%2C%22parsedDate%22%3A%222024%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3ERidefelt%2C%20Peter%2C%20Johan%20Saldeen%2C%20Mandy%20Vogel%2C%20Uta%20Ceglarek%2C%20Wieland%20Kiess%2C%20and%20Anders%20Larsson.%20%26%23x201C%3BPediatric%20Reference%20Intervals%20for%20Serum%20Folate%20and%20Cobalamin%20Based%20on%20a%20European%20Population%20without%20Exposure%20to%20Folic%20Acid%20Fortification.%26%23x201D%3B%20%3Ci%3EScandinavian%20Journal%20of%20Clinical%20and%20Laboratory%20Investigation%3C%5C%2Fi%3E%20online%20ahead%20of%20print%2C%20no.%200%20%282024%29%3A%201%26%23×2013%3B5.%20%3Ca%20class%3D%27zp-ItemURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1080%5C%2F00365513.2024.2330918%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1080%5C%2F00365513.2024.2330918%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Pediatric%20reference%20intervals%20for%20serum%20folate%20and%20cobalamin%20based%20on%20a%20European%20population%20without%20exposure%20to%20folic%20acid%20fortification%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Peter%22%2C%22lastName%22%3A%22Ridefelt%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Johan%22%2C%22lastName%22%3A%22Saldeen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Uta%22%2C%22lastName%22%3A%22Ceglarek%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anders%22%2C%22lastName%22%3A%22Larsson%22%7D%5D%2C%22abstractNote%22%3A%22The%20aim%20of%20the%20present%20study%20was%20to%20define%20pediatric%20reference%20intervals%20for%20serum%20cobalamin%20and%20folate%20utilizing%20data%20generated%20from%20a%20population%20not%20exposed%20to%20food%20fortified%20with%20folic%20acid.%20Folate%20and%20cobalamin%20results%20analyzed%20by%20electrochemiluminescence%20immunoassay%20%28Roche%20Cobas%29%20were%20obtained%20from%202375%20children%20%282%20months%20to%2017.99%20years%20of%20age%29.%20The%20serum%20samples%20were%20collected%20between%202011%20and%202015%20as%20part%20of%20the%20LIFE%20%28Leipzig%20Research%20Centre%20for%20Civilization%20Diseases%29%20Child%20cohort%20study%20in%20Germany%2C%20where%20folic%20acid%20fortification%20of%20food%20is%20not%20mandated.%20These%20results%20were%20used%20to%20generate%20age-%20and%20gender-specific%20reference%20intervals%20presented%20as%20non-parametric%202.5%20and%2097.5%20percentiles.%20Because%20of%20a%20subsequent%20restandardisation%20of%20the%20Roche%20folate%20assay%20in%202016%2C%20folate%20values%20were%20recalculated%20accordingly%20for%20adaptation%20to%20results%20obtained%20using%20the%20present%20calibration.%20In%20both%20genders%2C%20folate%20concentrations%20decreased%20continuously%20with%20age%2C%20whereas%20cobalamin%20concentrations%20peaked%20at%20five%20years%20of%20age%20and%20then%20declined.%20Teenage%20females%20had%20higher%20concentrations%20of%20cobalamin%20in%20the%20age%20group%2012%5Cu201317.99%20years.%22%2C%22date%22%3A%222024%22%2C%22language%22%3A%22%22%2C%22DOI%22%3A%2210.1080%5C%2F00365513.2024.2330918%22%2C%22ISSN%22%3A%220036-5513%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1080%5C%2F00365513.2024.2330918%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222024-08-27T12%3A39%3A37Z%22%7D%7D%2C%7B%22key%22%3A%22PJIEJAUS%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Strauch%20et%20al.%22%2C%22parsedDate%22%3A%222023-09-01%22%2C%22numChildren%22%3A2%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EStrauch%2C%20Jacqueline-Mich%26%23xE9%3Ble%2C%20Mandy%20Vogel%2C%20Christof%20Meigen%2C%20Uta%20Ceglarek%2C%20J%26%23xFC%3Brgen%20Kratzsch%2C%20Anja%20Willenberg%2C%20and%20Wieland%20Kiess.%20%26%23x201C%3BPediatric%20Reference%20Values%20of%20Alkaline%20Phosphatase%3A%20Analysis%20from%20a%20German%20Population-Based%20Cohort%20and%20Influence%20of%20Anthropometric%20and%20Blood%20Parameters.%26%23x201D%3B%20%3Ci%3EBone%3C%5C%2Fi%3E%20174%20%28September%201%2C%202023%29%3A%20116809.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.bone.2023.116809%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.bone.2023.116809%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Pediatric%20reference%20values%20of%20alkaline%20phosphatase%3A%20Analysis%20from%20a%20German%20population-based%20cohort%20and%20influence%20of%20anthropometric%20and%20blood%20parameters%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jacqueline-Mich%5Cu00e9le%22%2C%22lastName%22%3A%22Strauch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christof%22%2C%22lastName%22%3A%22Meigen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Uta%22%2C%22lastName%22%3A%22Ceglarek%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J%5Cu00fcrgen%22%2C%22lastName%22%3A%22Kratzsch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anja%22%2C%22lastName%22%3A%22Willenberg%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%5D%2C%22abstractNote%22%3A%22Background%5CnDue%20to%20different%20growth%20and%20metabolic%20processes%2C%20reference%20values%20of%20alkaline%20phosphatase%20%28AP%29%20for%20children%20aged%203%5Cu00a0month%20to%2018%5Cu00a0years%20are%20dependent%20on%20age%20and%20sex.%20They%20are%20not%20constant%20and%20differ%20from%20those%20of%20adults%20due%20to%20the%20growth%20processes%20taking%20place.%20Accordingly%2C%20reference%20levels%20of%20AP%20continuous%20across%20these%20ages%20were%20generated%20for%20boys%20and%20girls%20based%20on%20of%20a%20large%20German%20health-%20and%20population-based%20study%2C%20LIFE%20Child.%20We%20considered%20AP%20at%20different%20growth%20and%20Tanner%20stages%20and%20additionally%20its%20association%20with%20other%20anthropometric%20parameters.%20The%20association%20between%20AP%20and%20BMI%20was%20of%20particulary%20great%20interest%20due%20to%20controversial%20literature%20on%20this%20topic.%20The%20role%20of%20AP%20in%20liver%20metabolism%20was%20investigated%20by%20examining%20ALAT%2C%20ASAT%2C%20and%20GGT.%5CnMethods%5Cn3976%20healthy%20children%20%2812%2C093%20visits%29%20were%20included%20from%20the%20LIFE%20Child%20study%20from%202011%20to%202020.%20The%20subjects%5Cu00b4%20age%20ranged%20from%203%5Cu00a0months%20to%2018%5Cu00a0years.%20Serum%20samples%20from%203704%20subjects%20%2810%2C272%20cases%2C%201952%20boys%20and%201753%20girls%29%20were%20analysed%20for%20AP%20after%20applying%20specific%20exclusion%20criteria.%20After%20calculating%20of%20reference%20percentiles%2C%20associations%20between%20AP%20and%20height-SDS%2C%20growth%20velocity%2C%20BMI-SDS%2C%20Tanner%20stage%20and%20the%20liver%20enzymes%20ALAT%2C%20ASAT%20and%20GGT%20were%20examined%20via%20linear%20regression%20models.%5CnResults%5CnIn%20the%20continuous%20reference%20levels%2C%20AP%20showed%20a%20first%20peak%20during%20the%20first%20year%20of%20life%2C%20followed%20by%20a%20plateau%20at%20a%20lower%20level%20until%20the%20start%20of%20puberty.%20In%20girls%2C%20AP%20increased%20beginning%20at%20the%20age%208%2C%20with%20a%20peak%20around%2011%5Cu00a0years%2C%20in%20boys%20beginning%20at%20the%20age%209%2C%20with%20a%20peak%20around%20age%2013.%20Afterwards%2C%20AP%20values%20decreased%20continuously%20until%20age%2018.%20In%20Tanner%20stages%201%20and%202%2C%20AP%20levels%20did%20not%20differ%20between%20the%20two%20sexes.%20We%20found%20a%20strong%20positive%20association%20between%20AP-SDS%20and%20BMI-SDS.%20We%20also%20observed%20a%20significantly%20positive%20association%20between%20AP-SDS%20and%20height-SDS%2C%20which%20was%20stronger%20in%20boys%20than%20in%20girls.%20We%20found%20different%20intensities%20in%20the%20associations%20of%20AP%20with%20growth%20velocity%20depending%20on%20age%20group%20and%20sex.%20Furthermore%2C%20we%20found%20a%20significantly%20positive%20association%20between%20ALAT%20and%20AP%20in%20girls%20but%20not%20in%20boys%2C%20whereas%20ASAT-SDS%20and%20GGT-SDS%20were%20significantly%20positively%20associated%20with%20AP-SDS%20in%20both%20sexes.%5CnConclusion%5CnSex%20and%20age%2C%20but%20also%20BMI%20may%20act%20as%20confounding%20factors%20for%20AP%20reference%20ranges.%20Our%20data%20confirm%20the%20remarkable%20association%20between%20AP%20and%20growth%20velocity%20%28or%20height-SDS%2C%20respectively%29%20during%20infancy%20and%20puberty.%20In%20addition%2C%20we%20were%20able%20to%20specify%20the%20associations%20between%20AP%20and%20ALAT%2C%20ASAT%2C%20and%20GGT%20and%20their%20differences%20in%20both%20sexes.%20These%20relations%20should%20be%20considered%20when%20evaluating%20liver%20and%20bone%20metabolism%20markers%2C%20especially%20in%20infancy.%22%2C%22date%22%3A%222023-09-01%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1016%5C%2Fj.bone.2023.116809%22%2C%22ISSN%22%3A%228756-3282%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.sciencedirect.com%5C%2Fscience%5C%2Farticle%5C%2Fpii%5C%2FS8756328223001424%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222024-06-21T06%3A52%3A58Z%22%7D%7D%2C%7B%22key%22%3A%223PM9343R%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Maidowski%20et%20al.%22%2C%22parsedDate%22%3A%222023-08-02%22%2C%22numChildren%22%3A2%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EMaidowski%2C%20Ludwig%2C%20Wieland%20Kiess%2C%20Ronny%20Baber%2C%20Anne%20Dathan-Stumpf%2C%20Uta%20Ceglarek%2C%20and%20Mandy%20Vogel.%20%26%23x201C%3BTracking%20of%20Serum%20Lipids%20in%20Healthy%20Children%20on%20a%20Year-to-Year%20Basis.%26%23x201D%3B%20%3Ci%3EBMC%20Cardiovascular%20Disorders%3C%5C%2Fi%3E%2023%2C%20no.%201%20%28August%202%2C%202023%29%3A%20386.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs12872-023-03391-9%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs12872-023-03391-9%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Tracking%20of%20serum%20lipids%20in%20healthy%20children%20on%20a%20year-to-year%20basis%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ludwig%22%2C%22lastName%22%3A%22Maidowski%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ronny%22%2C%22lastName%22%3A%22Baber%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anne%22%2C%22lastName%22%3A%22Dathan-Stumpf%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Uta%22%2C%22lastName%22%3A%22Ceglarek%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%5D%2C%22abstractNote%22%3A%22OBJECTIVES%3A%20To%20assess%20the%20stability%20of%20lipid%20profiles%20throughout%20childhood%20and%20evaluate%20their%20onset%20and%20dynamic.%5CnMATERIALS%20AND%20METHODS%3A%20Lipid%20markers%20were%20longitudinally%20measured%20in%20more%20than%201300%20healthy%20children%20from%20the%20LIFE%20Child%20study%20%28Germany%29%20and%20categorized%20into%20normal%2C%20at-risk%2C%20or%20adverse.%20Year-to-year%20intra-person%20persistence%20of%20the%20categories%20during%20follow-ups%20was%20examined%20and%20Pearson%27s%20correlation%20coefficient%20was%20calculated.%5CnRESULTS%3A%20We%20found%20strong%20positive%20correlations%20for%20TC%2C%20LDL-C%20and%20ApoB%20%28r%5Cu2009%3E%5Cu20090.75%2C%20p%5Cu2009%3C%5Cu20090.001%29%20from%20the%20age%20of%20four%20years.%20Correlations%20were%20lowest%20during%20the%20first%20two%20years%20of%20life.%20Most%20children%20with%20normal%20levels%20also%20had%20normal%20levels%20the%20following%20year.%20Children%20with%20at-risk%20levels%20showed%20a%20tendency%20towards%20normal%20levels%20at%20the%20follow-up%20visit.%20Adverse%20levels%20of%20TC%2C%20LDL-C%2C%20ApoB%20%28all%20ages%29%2C%20and%20HDL-C%20%28from%20age%2015%29%20persisted%20in%20more%20than%20half%20of%20the%20affected%20children.%20Age-dependent%20patterns%20of%20stability%20were%20most%20pronounced%20and%20similar%20for%20TC%2C%20LDL-C%2C%20and%20ApoB.%5CnCONCLUSIONS%3A%20Normal%20levels%20of%20serum%20lipids%20show%20high%20stability%20and%20adverse%20levels%20stabilized%20in%20early%20childhood%20for%20TC%2C%20LDL%2C%20and%20ApoB.%20At-risk%20and%20adverse%20levels%20of%20TC%2C%20LDL-C%20or%20ApoB%20may%20warrant%20further%20or%20repeated%20diagnostic%20measurements%20with%20regards%20to%20preventing%20CVD%20in%20the%20long%20run.%22%2C%22date%22%3A%222023-08-02%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1186%5C%2Fs12872-023-03391-9%22%2C%22ISSN%22%3A%221471-2261%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222024-08-27T13%3A09%3A58Z%22%7D%7D%2C%7B%22key%22%3A%22RWLYJMIU%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22St%5Cu00fcrzebecher%20et%20al.%22%2C%22parsedDate%22%3A%222023-08-01%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3ESt%26%23xFC%3Brzebecher%2C%20P.%2C%20M.%20Schlingmann%2C%20K.%20Uttinger%2C%20M.%20Vogel%2C%20U.%20Ceglarek%2C%20B.%20Isermann%2C%20W.%20Kiess%2C%20A.%20K%26%23xF6%3Brner%2C%20and%20U.%20Laufs.%20%26%23x201C%3BLipoprotein%28A%29%20Serum%20Concentrations%20in%20Children%20Are%20Independent%20of%20Age%2C%20Sex%2C%20or%20Body%20Mass%20Index.%26%23x201D%3B%20In%20%3Ci%3EAtherosclerosis%3C%5C%2Fi%3E%2C%20379%3AS20.%20Elsevier%2C%202023.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.atherosclerosis.2023.06.739%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.atherosclerosis.2023.06.739%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22conferencePaper%22%2C%22title%22%3A%22Lipoprotein%28A%29%20serum%20concentrations%20in%20children%20are%20independent%20of%20age%2C%20sex%2C%20or%20body%20mass%20index%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22P.%22%2C%22lastName%22%3A%22St%5Cu00fcrzebecher%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22M.%22%2C%22lastName%22%3A%22Schlingmann%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22K.%22%2C%22lastName%22%3A%22Uttinger%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22M.%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22U.%22%2C%22lastName%22%3A%22Ceglarek%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22B.%22%2C%22lastName%22%3A%22Isermann%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22W.%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22A.%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22U.%22%2C%22lastName%22%3A%22Laufs%22%7D%5D%2C%22abstractNote%22%3A%22%22%2C%22date%22%3A%222023-08-01%22%2C%22proceedingsTitle%22%3A%22Atherosclerosis%22%2C%22conferenceName%22%3A%22%22%2C%22language%22%3A%22English%22%2C%22DOI%22%3A%2210.1016%5C%2Fj.atherosclerosis.2023.06.739%22%2C%22ISBN%22%3A%22%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.atherosclerosis-journal.com%5C%2Farticle%5C%2FS0021-9150%2823%2904831-1%5C%2Ffulltext%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222024-08-27T13%3A10%3A07Z%22%7D%7D%2C%7B%22key%22%3A%22KXRLYRQ4%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22S%5Cu00f6hnel%20et%20al.%22%2C%22parsedDate%22%3A%222023-03-17%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3ES%26%23xF6%3Bhnel%2C%20Tanja%2C%20Christof%20Meigen%2C%20Andreas%20Hiemisch%2C%20Siegfried%20Wahl%2C%20Focke%20Ziemssen%2C%20Carolin%20Truckenbrod%2C%20Katharina%20H%26%23xFC%3Bbner%2C%20and%20Wieland%20Kiess.%20%26%23x201C%3BNormative%20Data%20for%20Macular%20and%20Retinal%20Nerve%20Fibre%20Layer%20Thickness%20in%20Healthy%20German%20Children%20and%20Adolescents%20Using%20Optical%20Coherence%20Tomography.%26%23x201D%3B%20%3Ci%3EOphthalmic%20and%20Physiological%20Optics%3C%5C%2Fi%3E%2C%20March%2017%2C%202023%2C%20opo.13123.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fopo.13123%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fopo.13123%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Normative%20data%20for%20macular%20and%20retinal%20nerve%20fibre%20layer%20thickness%20in%20healthy%20German%20children%20and%20adolescents%20using%20optical%20coherence%20tomography%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22S%5Cu00f6hnel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christof%22%2C%22lastName%22%3A%22Meigen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andreas%22%2C%22lastName%22%3A%22Hiemisch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Siegfried%22%2C%22lastName%22%3A%22Wahl%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Focke%22%2C%22lastName%22%3A%22Ziemssen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Carolin%22%2C%22lastName%22%3A%22Truckenbrod%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Katharina%22%2C%22lastName%22%3A%22H%5Cu00fcbner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%5D%2C%22abstractNote%22%3A%22Purpose%3A%20To%20establish%20normative%20data%20for%20macular%20thickness%2C%20macular%20volume%20and%20peripapillary%20retinal%20nerve%20fibre%20layer%20%28RNFL%29%20thickness%20using%20Spectralis%5Cu00ae%20spectral-%5Cu00ad%20domain%20optical%20coherence%20tomography%20%28SD-%5Cu00adOCT%29%20in%20healthy%20German%20children%20and%20adolescents%20and%20investigate%20influencing%20factors.%5CnMethods%3A%20The%20cross-%5Cu00adsectional%20study%20included%20the%20right%20eye%20of%20695%20children%20with%20at%20least%20one%20complete%20retinal%20OCT%20scan.%20As%20part%20of%20the%20LIFE%20Child%20study%2C%20the%20children%20underwent%20an%20ophthalmological%20examination%20including%20axial%20length%20%28AL%29%2C%20spherical%20equivalent%20%28SE%29%20and%20OCT%20measurements.%20Various%20questionnaires%20were%20answered%20by%20the%20children%20or%20their%20parents%20to%20identify%20media%20use%20or%20outdoor%20time.%20Multiple%20linear%20regression%20models%20were%20used%20to%20investigate%20the%20potential%20influencing%20factors.%5CnResults%3A%20A%20total%20of%20342%20boys%20and%20353%20girls%20with%20an%20average%20age%20%28SD%29%20of%2012.91%20%283.29%29%20years%20participated.%20The%20mean%20AL%20%28SD%29%20was%2023.20%20%280.86%29%20mm.%20The%20mean%20macular%20thickness%20%28SD%29%20was%20320.53%20%2812.29%29%20%5Cu03bcm%20and%20the%20mean%20RNFL%20thickness%20%28SD%29%20was%20102.88%20%288.79%29%20%5Cu03bcm.%20Statistical%20analysis%20revealed%20a%20significant%20correlation%20between%20average%20macular%20thickness%20and%20age%20%28p%5Cu2009%3C%5Cu20090.001%2C%20%5Cu03b2%20%3D%200.77%29%20as%20well%20as%20AL%20%28p%5Cu2009%3C%5Cu20090.001%2C%20%5Cu03b2%20%3D%20%5Cu22124.06%29.%20In%20addition%2C%20boys%20had%20thicker%20maculae%20%28p%5Cu2009%3C%5Cu20090.001%2C%20%5Cu03b2%20%3D%205.36%29.%20The%20RNFL%20thickness%20showed%20no%20significant%20correlation%20with%20children%27s%20age%20%28p%5Cu2009%3E%5Cu20090.05%29%2C%20but%20with%20AL%20%28p%20%3D%200.002%2C%20%5Cu03b2%20%3D%20%5Cu22122.15%29%2C%20birth%20weight%20%28p%20%3D%200.02%2C%20%5Cu03b2%20%3D%200.003%29%20and%20a%20gender-%5Cu00adspecific%20effect%20of%20the%20body%20mass%20index%20standard%20deviation%20score%20for%20male%20participants%20%28p%20%3D%200.02%2C%20%5Cu03b2%20%3D%201.93%29.%5CnConclusion%3A%20This%20study%20provides%20normative%20data%20and%20correlations%20between%20macular%20and%20RNFL%20thickness%20in%20healthy%20German%20children.%20Especially%20age%2C%20gender%20and%20AL%20must%20be%20taken%20into%20account%20when%20evaluating%20quantitative%20OCT%20measurements%20to%20classify%20them%20as%20normal.%22%2C%22date%22%3A%222023-03-17%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1111%5C%2Fopo.13123%22%2C%22ISSN%22%3A%220275-5408%2C%201475-1313%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fonlinelibrary.wiley.com%5C%2Fdoi%5C%2F10.1111%5C%2Fopo.13123%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222024-08-27T13%3A11%3A16Z%22%7D%7D%2C%7B%22key%22%3A%226SC3V55H%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Brunnert%20et%20al.%22%2C%22parsedDate%22%3A%222022-09-27%22%2C%22numChildren%22%3A2%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EBrunnert%2C%20Lina%2C%20Ika%20Damayanti%20Puasa%2C%20Antje%20Garten%2C%20Melanie%20Penke%2C%20Susanne%20Gaul%2C%20Nico%20Grafe%2C%20Thomas%20Karlas%2C%20Wieland%20Kiess%2C%20Gunter%20Flemming%2C%20and%20Mandy%20Vogel.%20%26%23x201C%3BPediatric%20Percentiles%20for%20Transient%20Elastography%20Measurements%20-%20Effects%20of%20Age%2C%20Sex%2C%20Weight%20Status%20and%20Pubertal%20Stage.%26%23x201D%3B%20%3Ci%3EFrontiers%20in%20Endocrinology%3C%5C%2Fi%3E%2013%20%28September%2027%2C%202022%29%3A%201030809.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3389%5C%2Ffendo.2022.1030809%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3389%5C%2Ffendo.2022.1030809%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Pediatric%20percentiles%20for%20transient%20elastography%20measurements%20-%20effects%20of%20age%2C%20sex%2C%20weight%20status%20and%20pubertal%20stage%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Lina%22%2C%22lastName%22%3A%22Brunnert%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ika%20Damayanti%22%2C%22lastName%22%3A%22Puasa%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22Garten%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Melanie%22%2C%22lastName%22%3A%22Penke%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Susanne%22%2C%22lastName%22%3A%22Gaul%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Nico%22%2C%22lastName%22%3A%22Grafe%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Thomas%22%2C%22lastName%22%3A%22Karlas%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Gunter%22%2C%22lastName%22%3A%22Flemming%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%5D%2C%22abstractNote%22%3A%22Background%20and%20aims%5CnTransient%20Elastography%20is%20a%20non-invasive%2C%20cost-efficient%2C%20non-ionizing%2C%20observer-independent%20and%20reliable%20method%20to%20detect%20liver%20fibrosis%20using%20Liver%20Stiffness%20Measurement%20%28LSM%29%20and%20the%20degree%20of%20fat%20accumulation%20in%20the%20liver%20using%20Controlled%20Attenuation%20Parameter%20%28CAP%29.%20This%20study%20aims%20to%20derive%20reference%20values%20for%20both%20measures%20from%20healthy%20children%20and%20adolescents.%20Further%2C%20we%20aim%20to%20assess%20the%20potential%20influence%20of%20age%2C%20sex%2C%20puberty%2C%20and%20BMI-SDS%20on%20CAP%20and%20LSM.%5Cn%5CnMethods%5CnWithin%20the%20LIFE%20Child%20study%2C%20amongst%20others%2C%20anthropometric%20data%20and%20pubertal%20status%20were%20assessed.%20Transient%20Elastography%20%28TE%29%20was%20performed%20using%20the%20FibroScan%5Cu00ae%20device%20in%20a%20population-based%20cohort%20at%20982%20study%20visits%20of%20482%20healthy%20children%20aged%20between%2010%20and%2018%20years.%20Percentiles%20for%20LSM%20and%20CAP%20were%20estimated%2C%20and%20the%20effects%20of%20age%2C%20sex%2C%20puberty%20and%20weight%20status%20were%20assessed%20through%20hierarchical%20regression%20models.%5Cn%5CnResults%5CnThere%20was%20a%20strong%20age%20dependency%20for%20LSM%20with%20higher%20values%20for%20older%20children%2C%20most%20pronounced%20in%20the%20upper%20percentiles%20in%20boys.%20Contrarily%2C%20CAP%20was%20relatively%20stable%20across%20the%20age%20span%20without%20considerable%20difference%20between%20boys%20and%20girls.%20We%20found%20a%20significant%20positive%20correlation%20between%20BMI-SDS%20and%20both%20CAP%20and%20LSM%20for%20BMI-SDS%20%3E1.28.%20For%20BMI-SDS%20%3C%201.28%2C%20the%20association%20was%20also%20positive%20but%20reached%20statistical%20significance%20only%20for%20CAP.%20Further%2C%20the%20association%20between%20BMI-SDS%20and%20CAP%20was%20significantly%20stronger%20in%20younger%20than%20in%20older%20children.%20There%20was%20no%20association%20between%20pubertal%20status%20and%20CAP.%20For%20LSM%2C%20we%20found%20that%20children%20with%20a%20high%20BMI-SDS%20but%20not%20children%20with%20normal%20weight%20had%20significantly%20higher%20LSM%20values%20in%20Tanner%20stage%204.%5Cn%5CnConclusions%5CnAge%2C%20sex%2C%20pubertal%20status%20and%20weight%20status%20should%20be%20considered%20when%20interpreting%20LSM%20and%20CAP%20in%20pediatric%20patients%20to%20facilitate%20and%20improve%20early%20detection%20of%20abnormal%20liver%20function%2C%20which%20is%20associated%20with%20common%20pathologies%2C%20such%20as%20NAFLD.%22%2C%22date%22%3A%222022-9-27%22%2C%22language%22%3A%22%22%2C%22DOI%22%3A%2210.3389%5C%2Ffendo.2022.1030809%22%2C%22ISSN%22%3A%221664-2392%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.ncbi.nlm.nih.gov%5C%2Fpmc%5C%2Farticles%5C%2FPMC9551398%5C%2F%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-12-31T12%3A03%3A53Z%22%7D%7D%2C%7B%22key%22%3A%2288QIW45G%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22H%5Cu00f6renz%20et%20al.%22%2C%22parsedDate%22%3A%222022-03-16%22%2C%22numChildren%22%3A3%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EH%26%23xF6%3Brenz%2C%20Charlott%2C%20Mandy%20Vogel%2C%20Kerstin%20Wirkner%2C%20Uta%20Ceglarek%2C%20Joachim%20Thiery%2C%20Roland%20Pf%26%23xE4%3Bffle%2C%20Wieland%20Kiess%2C%20and%20J%26%23xFC%3Brgen%20Kratzsch.%20%26%23x201C%3BBMI%20and%20Contraceptives%20Affect%20New%20Age-%2C%20Sex-%2C%20and%20Puberty-Adjusted%20IGF-I%20and%20IGFBP-3%20Reference%20Ranges%20Across%20Life%20Span.%26%23x201D%3B%20%3Ci%3EThe%20Journal%20of%20Clinical%20Endocrinology%20%26amp%3B%20Metabolism%3C%5C%2Fi%3E%2C%20March%2016%2C%202022%2C%20dgac157.%20%3Ca%20class%3D%27zp-ItemURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1210%5C%2Fclinem%5C%2Fdgac157%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1210%5C%2Fclinem%5C%2Fdgac157%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22BMI%20and%20Contraceptives%20Affect%20New%20Age-%2C%20Sex-%2C%20and%20Puberty-adjusted%20IGF-I%20and%20IGFBP-3%20Reference%20Ranges%20Across%20Life%20Span%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Charlott%22%2C%22lastName%22%3A%22H%5Cu00f6renz%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Kerstin%22%2C%22lastName%22%3A%22Wirkner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Uta%22%2C%22lastName%22%3A%22Ceglarek%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Joachim%22%2C%22lastName%22%3A%22Thiery%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Roland%22%2C%22lastName%22%3A%22Pf%5Cu00e4ffle%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J%5Cu00fcrgen%22%2C%22lastName%22%3A%22Kratzsch%22%7D%5D%2C%22abstractNote%22%3A%22Various%20clinical%20factors%20influencing%20serum%20levels%20of%20insulin-like%20growth%20factor%20I%20%28IGF-I%29%20and%20its%20binding%20protein%203%20%28IGFBP-3%29%20are%20not%20entirely%20consistently%20described.We%20asked%20whether%20body%20mass%20index%20%28BMI%29%2C%20contraceptive%20drugs%20%28CDs%29%2C%20and%20hormone%20replacement%20therapy%20%28HRT%29%20have%20potential%20effects%20on%20data%20for%20interpreting%20new%20age-%2C%20sex-%2C%20and%20puberty-adjusted%20reference%20ranges%20for%20IGF-I%20and%20IGFBP-3%20serum%20levels.%20Subjects%20were%20mainly%20participants%20from%202%20population-based%20cohort%20studies%3A%20the%20LIFE%20Child%20study%20of%20children%20and%20adolescents%20and%20the%20LIFE%20Adult%20study.We%20investigated%209400%20serum%20samples%20from%20more%20than%207000%20healthy%20and%201278%20obese%20subjects%20between%203%20months%20and%2081%20years%20old.Associations%20between%20IGF-I%20or%20IGFBP-3%2C%20measured%20with%20a%20new%20electrochemiluminescence%20immunoassay%2C%20and%20the%20predictors%20BMI%20and%20CDs%20were%20estimated%20using%20hierarchical%20linear%20modeling.During%20infancy%2C%20obese%20children%20had%20up%20to%201%20SD%20score%20%28SDS%29%20higher%20mean%20predicted%20IGF-I%20values%2C%20converging%20with%20levels%20of%20normal-weight%20subjects%20up%20to%2013%20years%20old.%20Between%2020%20and%2040%20years%20of%20age%2C%20obesity%20was%20related%20to%20up%20to%20%5Cu22120.5%20lower%20IGF-I%20SDS%20values%20than%20the%20predicted%20values.%20Obesity%20had%20less%20impact%20on%20IGFBP-3.%20Estrogen-%20and%20progestin-based%20CDs%2C%20but%20not%20HRT%2C%20decreased%20IGF-I%20and%20increased%20IGFBP-3%20%28P%5Cu2005%26lt%3B%5Cu20050.01%29%20in%20adolescents%20%28%5Cu03b2%5Cu200aIGF-I%5Cu2005%3D%5Cu2005%5Cu22120.45%2C%20%5Cu03b2%5Cu200aIGFBP-3%5Cu2005%5Cu2005%3D%200.94%29%20and%20adults%20%28%5Cu03b2%5Cu200aIGF-I%20%3D%20%5Cu20130.43%2C%20%5Cu03b2%5Cu200aIGFBP-3%5Cu2005%5Cu2005%3D%201.12%29.%20Conversely%2C%20progestin-based%20CDs%20were%20significantly%20positive%20associated%20with%20IGF-I%20%28%5Cu03b2%5Cu200aIGF-I%5Cu2005%5Cu2005%3D0.82%29.BMI%20and%20CDs%20must%20be%20considered%20when%20assessing%20and%20interpreting%20the%20clinical%20relevance%20of%20IGF-I%20and%20IGFBP-3%20measurements.%22%2C%22date%22%3A%222022-03-16%22%2C%22language%22%3A%22%22%2C%22DOI%22%3A%2210.1210%5C%2Fclinem%5C%2Fdgac157%22%2C%22ISSN%22%3A%220021-972X%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1210%5C%2Fclinem%5C%2Fdgac157%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222024-04-24T06%3A30%3A35Z%22%7D%7D%2C%7B%22key%22%3A%22LHXDPTK8%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Kiess%20et%20al.%22%2C%22parsedDate%22%3A%222022-03-12%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EKiess%2C%20Alexandra%2C%20Jessica%20Green%2C%20Anja%20Willenberg%2C%20Uta%20Ceglarek%2C%20Ingo%20D%26%23xE4%3Bhnert%2C%20Anne%20Jurkutat%2C%20Antje%20K%26%23xF6%3Brner%2C%20Andreas%20Hiemisch%2C%20Wieland%20Kiess%2C%20and%20Mandy%20Vogel.%20%26%23x201C%3BAge-Dependent%20Reference%20Values%20for%20Hs-Troponin%20T%20and%20Nt-Probnp%20and%20Determining%20Factors%20in%20a%20Cohort%20of%20Healthy%20Children%20%28the%20Life%20Child%20Study%29.%26%23x201D%3B%20%3Ci%3EPediatric%20Cardiology%3C%5C%2Fi%3E%2043%20%28March%2012%2C%202022%29%3A%201071%26%23×2013%3B83.%20%3Ca%20class%3D%27zp-ItemURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs00246-022-02827-x%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs00246-022-02827-x%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Age-Dependent%20Reference%20Values%20for%20Hs-Troponin%20T%20and%20Nt-Probnp%20and%20Determining%20Factors%20in%20a%20Cohort%20of%20Healthy%20Children%20%28the%20Life%20Child%20Study%29%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Alexandra%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jessica%22%2C%22lastName%22%3A%22Green%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anja%22%2C%22lastName%22%3A%22Willenberg%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Uta%22%2C%22lastName%22%3A%22Ceglarek%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ingo%22%2C%22lastName%22%3A%22D%5Cu00e4hnert%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anne%22%2C%22lastName%22%3A%22Jurkutat%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andreas%22%2C%22lastName%22%3A%22Hiemisch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%5D%2C%22abstractNote%22%3A%22This%20study%20aimed%20to%20provide%20reliable%20pediatric%20reference%20values%20for%20N-terminal%20pro-brain%20natriuretic%20peptide%20%28NT-proBNP%29%20and%20high-sensitive%20Troponin%20T%20%28hsTnT%29%20obtained%20from%20a%20population%20of%20well%20children%20and%20investigate%20for%20associations%20with%20sex%2C%20pubertal%20status%2C%20body%20mass%20index%20%28BMI%29%2C%20and%20serum%20lipid%20levels.%20We%20analyzed%20hsTnT%20and%20NT-proBNP%20values%20obtained%20from%204826%20samples%20provided%20by%202522%20children%20aged%200.25%5Cu201318%5Cu00a0years%20participating%20in%20a%20prospective%20longitudinal%20population-based%20cohort%20study%2C%20%5Cu201cLIFE%20child%5Cu201d%20in%20Leipzig%2C%20Germany%20%28Poulain%20et%20al.%2C%20Eur%20J%20Epidemiol%2032%3A145%5Cu2013158%2C%202017%29.%20NT-proBNP%20values%20decreased%20throughout%20childhood%20from%20values%20over%20400%5Cu00a0ng%5C%2FL%20at%203%5Cu00a0months%20to%20138%5Cu00a0ng%5C%2FL%20in%20females%20and%2065%5Cu00a0ng%5C%2FL%20in%20males%20by%2018%5Cu00a0years%20of%20age.%20Values%20dropped%20rapidly%20with%20advancing%20pubertal%20stage.%20We%20found%20a%20strong%20association%20between%20lower%20NT-proBNP%20values%20and%20higher%20BMI%20or%20elevated%20serum%20lipids%2C%20the%20latter%20effect%20being%20more%20pronounced%20in%20males.%20For%20hsTnT%20levels%2C%20approximately%20half%20of%20the%20measurements%20were%20below%20the%20detection%20limit.%20However%2C%2076%25%20of%20those%20aged%203%5Cu00a0months%20and%2021%25%20of%20those%20aged%206%5Cu00a0months%20had%20values%20exceeding%20the%20adult%20cut-off%20limit.%20Females%20had%20slightly%20higher%20levels%20in%20the%20first%202%5Cu00a0years%20of%20life%20but%20this%20was%20reversed%20during%20puberty.%20In%20males%2C%20there%20was%20an%20upward%20trend%20from%20pubertal%20stage%202%20onward.%20We%20identified%20a%20positive%20association%20between%20hsTnT%20and%20BMI%20but%20a%20negative%20association%20with%20low-density%20lipoprotein%20%28LDL%29%20cholesterol%20and%20triglyceride%20levels%20in%20boys%20but%20not%20in%20girls.%20Based%20on%20a%20large%20number%20of%20healthy%20children%2C%20we%20have%20established%20reliable%20reference%20values%20for%20NT-proBNP%20and%20hsTnT%20for%20use%20in%20everyday%20clinical%20practice.%20We%20have%20also%20identified%20important%20associations%20between%20certain%20metabolic%20and%20cardiac%20markers.%22%2C%22date%22%3A%222022-03-12%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1007%5C%2Fs00246-022-02827-x%22%2C%22ISSN%22%3A%221432-1971%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs00246-022-02827-x%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-12-28T18%3A29%3A05Z%22%7D%7D%2C%7B%22key%22%3A%22DZCUIAH7%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Hovestadt%20et%20al.%22%2C%22parsedDate%22%3A%222022-03%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EHovestadt%2C%20Ina%2C%20Wieland%20Kiess%2C%20Christiane%20Lewien%2C%20Anja%20Willenberg%2C%20Tanja%20Poulain%2C%20Christof%20Meigen%2C%20Antje%20K%26%23xF6%3Brner%2C%20and%20Mandy%20Vogel.%20%26%23x201C%3BHbA1c%20Percentiles%20and%20the%20Association%20between%20BMI%2C%20Age%2C%20Gender%2C%20Puberty%20and%20HbA1c%20Levels%20in%20Healthy%20German%20Children%20and%20Adolescents.%26%23x201D%3B%20%3Ci%3EPediatric%20Diabetes%3C%5C%2Fi%3E%2023%2C%20no.%202%20%28March%202022%29%3A%20194%26%23×2013%3B202.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fpedi.13297%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fpedi.13297%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22HbA1c%20Percentiles%20and%20the%20Association%20between%20BMI%2C%20Age%2C%20Gender%2C%20Puberty%20and%20HbA1c%20Levels%20in%20Healthy%20German%20Children%20and%20Adolescents%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ina%22%2C%22lastName%22%3A%22Hovestadt%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christiane%22%2C%22lastName%22%3A%22Lewien%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anja%22%2C%22lastName%22%3A%22Willenberg%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christof%22%2C%22lastName%22%3A%22Meigen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%5D%2C%22abstractNote%22%3A%22OBJECTIVE%3A%20The%20measurement%20of%20glycated%20haemoglobin%20%28HbA1c%29%20represents%20one%20way%20to%20detect%20type%201%20and%202%20diabetes%20in%20children%20at%20an%20early%20stage.%20However%2C%20to%20date%2C%20variations%20in%20HbA1c%20levels%20are%20not%20fully%20understood%2C%20even%20in%20healthy%20children.%20With%20this%20in%20mind%2C%20the%20present%20study%20aimed%20to%20establish%20HbA1c%20reference%20values%20in%20healthy%20children%20and%20to%20investigate%20the%20influence%20of%20various%20independent%20variables.%5CnSTUDY%20DESIGN%20AND%20METHODS%3A%202%2C455%20healthy%20children%20and%20adolescents%20aged%20between%200.5%20and%2018%5Cu2009years%20participated%20in%20the%20population-based%20cohort%20study%20LIFE%20Child%2C%20Germany.%20Age-%20and%20gender-dependent%20percentiles%20were%20estimated%2C%20enabling%20HbA1c%20values%20to%20be%20converted%20into%20standard%20deviation%20scores%20%28SDS%29.%20Logistic%20regression%20models%20were%20applied%20to%20assess%20associations%20between%20HbA1c-SDS%20%28as%20outcome%29%20and%20age%2C%20gender%2C%20BMI%2C%20birth%20weight%2C%20physical%20activity%2C%20pubertal%20status%2C%20and%20socioeconomic%20status%20%28SES%29%20%28as%20explanatory%20variables%29.%5CnRESULTS%3A%20The%20mean%20HbA1c%20value%20was%2031.79%5Cu2009mmol%5C%2Fmol%20or%205.06%25%20%28SD%3D3.3mmol%5C%2Fmol%2C%20SD%3D0.3%25%29.%20Positive%20associations%20with%20HbA1c%20values%20were%20identified%20for%20age%20%28b%3D.09%2C%20p%3C.001%29%2C%20gender%20%28b%3D0.25%2C%20p%3D.007%29%20and%20BMI-SDS%20%28b%3D.06%2C%20p%3C.001%29.%20In%20addition%2C%20obesity%20was%20related%20to%20higher%20HbA1c%20values%20%28b%3D.29%2C%20p%3C.001%29.%20Compared%20to%20prepuberty%2C%20the%20pubertal%20and%20post-pubertal%20stages%20were%20associated%20with%20higher%20HbA1c%20levels.%20Furthermore%2C%20higher%20SES%20was%20associated%20with%20higher%20HbA1c-SDS%20%28b%3D.01%2C%20p%3D.04%29.%5CnCONCLUSION%3A%20The%20present%20study%20established%20HbA1c%20reference%20values%20based%20on%20a%20large%20sample%20of%20healthy%20German%20children%20and%20adolescents.%20Age%2C%20gender%2C%20socioeconomic%20status%2C%20pubertal%20stage%2C%20and%20BMI%20were%20found%20to%20be%20associated%20with%20higher%20HbA1c%20levels.%20This%20article%20is%20protected%20by%20copyright.%20All%20rights%20reserved.%22%2C%22date%22%3A%222022%5C%2F03%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1111%5C%2Fpedi.13297%22%2C%22ISSN%22%3A%221399-5448%22%2C%22url%22%3A%22http%3A%5C%2F%5C%2Forgid.org%5C%2F10.1111%5C%2Fpedi.13297%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222024-04-12T07%3A58%3A29Z%22%7D%7D%2C%7B%22key%22%3A%22CTCDE6NZ%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Wessela%20et%20al.%22%2C%22parsedDate%22%3A%222022-01%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EWessela%2C%20Sven%2C%20Christof%20Meigen%2C%20Tanja%20Poulain%2C%20Carolin%20Sobek%2C%20Mandy%20Vogel%2C%20Siegfried%20M%26%23xF6%3Bller%2C%20and%20Wieland%20Kiess.%20%26%23x201C%3BReference%20Centiles%20Based%20on%20Year-to-Year%20Changes%20for%20a%20Longitudinal%20Evaluation%20of%20Motor%20Performance%20in%20Children%20and%20Adolescents.%26%23x201D%3B%20%3Ci%3EPloS%20One%3C%5C%2Fi%3E%2017%2C%20no.%201%20%28January%202022%29%3A%20e0262163.%20%3Ca%20class%3D%27zp-ItemURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1371%5C%2Fjournal.pone.0262163%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1371%5C%2Fjournal.pone.0262163%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Reference%20Centiles%20Based%20on%20Year-to-Year%20Changes%20for%20a%20Longitudinal%20Evaluation%20of%20Motor%20Performance%20in%20Children%20and%20Adolescents%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Sven%22%2C%22lastName%22%3A%22Wessela%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christof%22%2C%22lastName%22%3A%22Meigen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Carolin%22%2C%22lastName%22%3A%22Sobek%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Siegfried%22%2C%22lastName%22%3A%22M%5Cu00f6ller%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%5D%2C%22abstractNote%22%3A%22OBJECTIVES%3A%20The%20aim%20was%20to%20evaluate%20the%20longitudinal%20course%20of%20motor%20skills%20development%20in%20children%20with%20a%20view%20to%20improve%20the%20understanding%20of%20intra-individual%20variance.%20Previous%20publications%20have%20been%20based%20on%20cross-sectional%20data%20or%20analyzed%20longitudinal%20studies%20in%20a%20cross-sectional%20manner.%5CnDESIGN%3A%20Longitudinal.%20Year-to-year%20change.%5CnMETHODS%3A%20The%20present%20study%20is%20based%20on%20motor%20function%20data%20collected%20in%20the%20LIFE%20Child%20study%20%28Germany%29.%20The%20participants%20%286%20to%2017%20years%29%20completed%20parts%20of%20the%20motor%20tests%20according%20to%20the%20standard%20of%20the%20German%20Motor%20Performance%20Test%206-18%20%28DMT%29.%20For%20a%20total%20of%201653%20participants%2C%204616%20motor%20tests%20with%20an%20annual%20interval%20in%20the%20period%202011%20to%202019%20were%20included%20in%20the%20evaluation.%5CnRESULTS%3A%20We%20were%20able%20to%20produce%20gender%20and%20age-specific%20change%20centiles%20for%20the%20test%20items%20standing%20long%20jump%2C%20jumping%20sideways%2C%20push-ups%2C%20stand%20and%20reach%20and%20balancing%20walking%20backwards.%20Each%20set%20of%20centiles%20revealed%20a%20range%20of%20variability%20in%20motor%20development%20in%20children%20and%20adolescents%2C%20with%20distinct%20progressive%20patterns%20in%20the%20different%20test%20items%20and%20different%20genders.%20The%20supplied%20tables%20offer%20an%20indication%20of%20expected%20year-to-year%20change%20for%20each%20test%20item%20depending%20on%20age%20and%20gender.%20Depending%20on%20the%20test%20item%20and%20the%20mean%20age%2C%20a%20deterioration%20in%20test%20results%20after%20a%20one-year%20interval%20was%20observed%2C%20despite%20cross-sectional%20centiles%20showing%20an%20upward%20trend.%5CnCONCLUSION%3A%20We%20present%20a%20user-friendly%20tool%20as%20a%20way%20to%20assess%20individual%20dynamic%20changes%20in%20motor%20development%20of%20children%20and%20adolescents.%20In%20combination%20with%20the%20well-known%20cross-sectional%20centiles%20as%20baseline%2C%20this%20can%20be%20helpful%20for%20the%20scientific%20evaluation%20of%20motor%20skills%20tests%20and%20can%20also%20be%20used%20in%20school%20settings.%22%2C%22date%22%3A%222022-01%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1371%5C%2Fjournal.pone.0262163%22%2C%22ISSN%22%3A%221932-6203%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1371%5C%2Fjournal.pone.0262163%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-24T13%3A53%3A39Z%22%7D%7D%2C%7B%22key%22%3A%22HLWE9S7M%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Dienerowitz%20et%20al.%22%2C%22parsedDate%22%3A%222021-12%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EDienerowitz%2C%20Tobias%2C%20Thomas%20Peschel%2C%20Mandy%20Vogel%2C%20Tanja%20Poulain%2C%20Christoph%20Engel%2C%20Wieland%20Kiess%2C%20Michael%20Fuchs%2C%20and%20Thomas%20Berger.%20%26%23x201C%3BEstablishing%20Normative%20Data%20on%20Singing%20Voice%20Parameters%20of%20Children%20and%20Adolescents%20with%20Average%20Singing%20Activity%20Using%20the%20Voice%20Range%20Profile.%26%23x201D%3B%20%3Ci%3EFolia%20Phoniatrica%20et%20Logopaedica%3A%20Official%20Organ%20of%20the%20International%20Association%20of%20Logopedics%20and%20Phoniatrics%20%28IALP%29%3C%5C%2Fi%3E%2073%2C%20no.%206%20%28December%202021%29.%20%3Ca%20class%3D%27zp-ItemURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1159%5C%2F000513521%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1159%5C%2F000513521%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Establishing%20Normative%20Data%20on%20Singing%20Voice%20Parameters%20of%20Children%20and%20Adolescents%20with%20Average%20Singing%20Activity%20Using%20the%20Voice%20Range%20Profile%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tobias%22%2C%22lastName%22%3A%22Dienerowitz%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Thomas%22%2C%22lastName%22%3A%22Peschel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christoph%22%2C%22lastName%22%3A%22Engel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Michael%22%2C%22lastName%22%3A%22Fuchs%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Thomas%22%2C%22lastName%22%3A%22Berger%22%7D%5D%2C%22abstractNote%22%3A%22PURPOSE%3A%20The%20purpose%20of%20this%20study%20was%20to%20establish%20and%20characterize%20age-%20and%20gender-specific%20normative%20data%20of%20the%20singing%20voice%20using%20the%20voice%20range%20profile%20for%20clinical%20diagnostics.%20Furthermore%2C%20associations%20between%20the%20singing%20voice%20and%20the%20socioeconomic%20status%20were%20examined.%5CnMETHODS%3A%20Singing%20voice%20profiles%20of%201%2C578%20mostly%20untrained%20children%20aged%20between%207.0%20and%2016.11%20years%20were%20analyzed.%20Participants%20had%20to%20reproduce%20sung%20tones%20at%20defined%20pitches%2C%20resulting%20in%20maximum%20and%20minimum%20fundamental%20frequency%20and%20sound%20pressure%20level%20%28SPL%29.%20In%20addition%2C%20maximum%20phonation%20time%20%28MPT%29%20was%20measured.%20Percentile%20curves%20of%20frequency%2C%20SPL%20and%20MPT%20were%20estimated.%20To%20examine%20the%20associations%20of%20socioeconomic%20status%2C%20multivariate%20analyses%20adjusted%20for%20age%20and%20sex%20were%20performed.%5CnRESULTS%3A%20In%20boys%2C%20the%20mean%20of%20the%20highest%20frequency%20was%20750.9%20Hz%20and%20lowered%20to%20397.1%20Hz%20with%20increasing%20age.%20Similarly%2C%20the%20minimum%20frequency%20was%20194.4%20Hz%20and%20lowered%20to%2091.9%20Hz.%20In%20girls%2C%20the%20mean%20maximum%20frequency%20decreased%20from%20754.9%20to%20725.3%20Hz.%20The%20mean%20minimum%20frequency%20lowered%20from%20202.4%20to%20175.0%20Hz.%20For%20both%20sexes%2C%20the%20mean%20frequency%20range%20%5Cu2206f%20showed%20a%20constant%20range%20of%20roughly%2024%20semitones.%20The%20MPT%20increased%20with%20age%2C%20for%20boys%20and%20girls.%20There%20was%20neither%20an%20effect%20of%20age%20nor%20sex%20on%20SPLmin%20or%20SPLmax%2C%20ranging%20between%2052.6%20and%2054.1%20dBA%20and%20between%2086.5%20and%2082.8%20dBA%2C%20respectively.%20Socioeconomic%20status%20was%20not%20associated%20with%20the%20above-mentioned%20variables.%5CnCONCLUSION%3A%20To%20our%20knowledge%2C%20this%20study%20is%20the%20first%20to%20present%20large%20normative%20data%20on%20the%20singing%20voice%20in%20childhood%20and%20adolescence%20based%20on%20a%20high%20number%20of%20measurements.%20In%20addition%2C%20we%20provide%20percentile%20curves%20for%20practical%20application%20in%20clinic%20and%20vocal%20pedagogy%20which%20may%20be%20applied%20to%20distinguish%20between%20normal%20and%20pathological%20singing%20voice.%22%2C%22date%22%3A%222021-12%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1159%5C%2F000513521%22%2C%22ISSN%22%3A%221421-9972%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1159%5C%2F000513521%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-07T07%3A01%3A51Z%22%7D%7D%2C%7B%22key%22%3A%22D3SQX7F2%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Kratzsch%20et%20al.%22%2C%22parsedDate%22%3A%222021-11%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EKratzsch%2C%20Juergen%2C%20Mandy%20Vogel%2C%20Tanja%20Poulain%2C%20and%20Wieland%20Kiess.%20%26%23x201C%3BNew%20Reference%20Intervals%20for%20Endocrinological%20Biomarkers%20in%20Pediatric%20Patients%3A%20What%20Can%20We%20Learn%20from%20the%20Life%20Child%20Study%3F%26%23x201D%3B%20%3Ci%3ELaboratoriumsMedizin%3C%5C%2Fi%3E%2045%2C%20no.%206%20%28November%202021%29.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1515%5C%2Flabmed-2021-0145%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1515%5C%2Flabmed-2021-0145%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22New%20Reference%20Intervals%20for%20Endocrinological%20Biomarkers%20in%20Pediatric%20Patients%3A%20What%20Can%20We%20Learn%20from%20the%20Life%20Child%20Study%3F%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Juergen%22%2C%22lastName%22%3A%22Kratzsch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%5D%2C%22abstractNote%22%3A%22Objectives%20We%20established%20reference%20intervals%20for%20serum%20concentrations%20of%20hormones%20from%20healthy%20pediatric%20subjects%20and%20investigated%20their%20associations%20with%20gender%2C%20body%20mass%20index%20%28BMI%29%2C%20puberty%20and%20oral%20contraceptives%20%28oC%29.%20Methods%20We%20calculated%20reference%20intervals%20for%20the%20thyroid%20parameters%20thyroid-stimulating%20hormone%20%28TSH%29%2C%20free%20triiodothyronine%20%28FT3%29%2C%20free%20thyroxine%20%28FT4%29%2C%20and%20calcitonin%20%28Ct%29%3B%20the%20bone%20markers%20osteocalcin%2C%20procolagen%20type%201%5Cu00a0N-propeptide%2C%20and%20carboxy-terminal%20cross-linking%20telopeptide%20of%20type%201%20collagen%3B%20the%20calciotropic%20hormones%2025-hydroxyvitamin%20D%20%2825%28OH%29D%29%20and%20parathyroid%20hormone%20and%20the%20steroids%20cortisol%2C%20progesterone%2C%2017-hydroxyprogesterone%2C%20androstenedione%2C%20testosterone%2C%20estradiol%2C%20dehydroepiandrosterone%20sulfate%20and%20aldosterone.%20Up%20to%2010%2C002%20blood%20serum%20samples%20from%203%2C229%20healthy%20children%20and%20adolescents%20%28age%20interval%3A%203%5Cu00a0months%20to%2020%20years%29%20were%20measured.%20To%20investigate%20the%20associations%20between%20the%20hormone%20levels%20with%20age%2C%20sex%2C%20weight%20status%20and%20the%20role%20of%20puberty-based%20changes%2C%20the%20measurement%20and%20BMI%20values%20were%20transformed%20into%20standard%20deviation%20scores.%20Results%20Most%20of%20the%20hormones%20depended%20on%20age-%20and%20gender.%20Puberty%20was%20linked%20to%20a%2C%20in%20part%2C%20temporary%20decrease%20in%20TSH%2C%20FT3%20%28for%20females%29%2C%20FT4%2C%20Ct%2C%20cortisol%20%28for%20girls%29%20and%20aldosterone%20%28for%20boys%29%20and%20peak%20in%20the%20bone%20marker%20and%20calciotropic%20hormones%20%28excluding%2025%28OH%29D%29%20and%20nearly%20all%20remaining%20steroids.%20BMI%20had%20effects%20on%20the%20thyroid%2C%20bone%2C%20and%20calciotropic%20parameters%2C%20whereas%20oC%20led%20to%20increased%20cortisol%2C%20suppressed%20progesterone%20and%20estradiol%20values.%20Conclusions%20Age-%20and%20gender-specific%20reference%20intervals%20are%20essential%20for%20the%20interpretation%20of%20pediatric%20patients%5Cu2019%20hormone%20measurements.%20Influencing%20factors%20as%20puberty%2C%20BMI%2C%20or%20oC%20should%20be%20taken%20into%20consideration%20for%20diagnosis%20and%20treatment%20monitoring.%22%2C%22date%22%3A%222021-11%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1515%5C%2Flabmed-2021-0145%22%2C%22ISSN%22%3A%221439-0477%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.degruyter.com%5C%2Fdocument%5C%2Fdoi%5C%2F10.1515%5C%2Flabmed-2021-0145%5C%2Fhtml%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-12-28T13%3A52%3A10Z%22%7D%7D%2C%7B%22key%22%3A%22ZPJVVPUK%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Eckelt%20et%20al.%22%2C%22parsedDate%22%3A%222021-09%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EEckelt%2C%20Felix%2C%20Roland%20Pfaeffle%2C%20Wieland%20Kiess%2C%20and%20Juergen%20Kratzsch.%20%26%23x201C%3BCalcitonin%20and%20Complementary%20Biomarkers%20in%20the%20Diagnosis%20of%20Hereditary%20Medullary%20Thyroid%20Carcinoma%20in%20Children%20and%20Adolescents.%26%23x201D%3B%20%3Ci%3EJournal%20of%20Pediatric%20Endocrinology%20%26amp%3B%20Metabolism%3A%20JPEM%3C%5C%2Fi%3E%20online%20ahead%20of%20print%20%28September%202021%29.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1515%5C%2Fjpem-2021-0163%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1515%5C%2Fjpem-2021-0163%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Calcitonin%20and%20Complementary%20Biomarkers%20in%20the%20Diagnosis%20of%20Hereditary%20Medullary%20Thyroid%20Carcinoma%20in%20Children%20and%20Adolescents%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Felix%22%2C%22lastName%22%3A%22Eckelt%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Roland%22%2C%22lastName%22%3A%22Pfaeffle%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Juergen%22%2C%22lastName%22%3A%22Kratzsch%22%7D%5D%2C%22abstractNote%22%3A%22OBJECTIVES%3A%20Medullary%20thyroid%20carcinoma%20%28MTC%29%20is%20a%20rare%20malignancy%20that%20is%20effectively%20curable%20by%20surgery.%20Unlike%20in%20adults%2C%20hereditary%20MTC%20has%20a%20predominant%20role%20in%20children.%20A%20fast%20and%20safe%20diagnosis%20is%20important%20to%20assure%20the%20good%20prognosis%20for%20the%20patients.%20A%20major%20cornerstone%20is%20the%20assessment%20of%20biomarkers%2C%20but%20the%20interpretation%20must%20respect%20their%20pre-%2C%20post-%20and%20analytical%20features.%20Especially%20calcitonin%20%28Ctn%29%20is%20a%20challenging%20biomarker%20in%20daily%20laboratory%20diagnostics.%20However%2C%20Ctn%20is%20of%20particular%20relevance%20for%20the%20diagnostic%20in%20MTC.%20The%20American%20Thyroid%20Association%20recommends%20thyroidectomy%20if%20the%20upper%20reference%20range%20of%20Ctn%20is%20exceeded.%20Interestingly%2C%20age-dependent%20reference%20ranges%20for%20children%20and%20adolescents%20have%20become%20available%20only%20recently%20for%20Ctn%20assays.%20With%20this%20review%2C%20we%20aim%20to%20highlight%20the%20importance%20of%20a%20timely%20diagnosis%20of%20MTC%20in%20children%20and%20adolescents.%5CnCONTENT%3A%20Recent%20developments%20in%20pediatric%20biochemical%20diagnostics%20of%20MTC%20were%20summarized.%20This%20includes%20guidance%20on%20interpretation%20of%20RET%2C%20Ctn%2C%20procalcitonin%2C%20carcinoembryonic%20antigen%2C%20carbohydrate%20antigen%2019-9%2C%20and%20chromogranin%20A.%5CnSUMMARY%3A%20Currently%2C%20Ctn%20is%20the%20most%20investigated%20biomarker%20in%20the%20diagnosis%20of%20MTC%20in%20children%20and%20adolescents.%20Other%20biomarkers%20as%20PCT%20suggest%20complementary%20evidence%20about%20pediatric%20MTC%20but%20their%20interpretation%20based%20largely%20on%20adult%27s%20data.%20A%20successful%20treatment%20of%20MTC%20requires%2C%20besides%20results%20of%20biomarkers%2C%20information%20about%20medical%20history%2C%20RET%20gene%20analysis%20and%20recent%20guideline%20knowledge.%5CnOUTLOOK%3A%20More%20research%20is%20required%20to%20validate%20complementary%20biomarkers%20of%20Ctn%20in%20children.%20Additionally%2C%20the%20effect%20of%20different%20confounder%20on%20pediatric%20Ctn%20levels%20has%20to%20be%20further%20clarified.%22%2C%22date%22%3A%222021-09%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1515%5C%2Fjpem-2021-0163%22%2C%22ISSN%22%3A%222191-0251%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Forgid.org%5C%2F10.1515%5C%2Fjpem-2021-0163%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-07T07%3A01%3A50Z%22%7D%7D%2C%7B%22key%22%3A%22EFWCUEVF%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Surup%20et%20al.%22%2C%22parsedDate%22%3A%222021-08%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3ESurup%2C%20Hans%2C%20Mandy%20Vogel%2C%20Antje%20Koerner%2C%20Andreas%20Hiemisch%2C%20Lea%20Oelkers%2C%20Anja%20Willenberg%2C%20Wieland%20Kiess%2C%20and%20Juergen%20Kratzsch.%20%26%23x201C%3BPediatric%20Reference%20Intervals%20for%20Thyrotropin%2C%20Free%20Triiodothyronine%2C%20and%20Free%20Thyroxine%20and%20the%20Relevance%20of%20Body%20Mass%20Index%20and%20Puberty%20in%20Measurement%20Interpretation.%26%23x201D%3B%20%3Ci%3EThyroid%3A%20Official%20Journal%20of%20the%20American%20Thyroid%20Association%3C%5C%2Fi%3E%2031%2C%20no.%208%20%28August%202021%29%3A%201192%26%23×2013%3B1202.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1089%5C%2Fthy.2020.0780%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1089%5C%2Fthy.2020.0780%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Pediatric%20Reference%20Intervals%20for%20Thyrotropin%2C%20Free%20Triiodothyronine%2C%20and%20Free%20Thyroxine%20and%20the%20Relevance%20of%20Body%20Mass%20Index%20and%20Puberty%20in%20Measurement%20Interpretation%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Hans%22%2C%22lastName%22%3A%22Surup%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22Koerner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andreas%22%2C%22lastName%22%3A%22Hiemisch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Lea%22%2C%22lastName%22%3A%22Oelkers%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anja%22%2C%22lastName%22%3A%22Willenberg%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Juergen%22%2C%22lastName%22%3A%22Kratzsch%22%7D%5D%2C%22abstractNote%22%3A%22Background%3A%20The%20present%20study%20aimed%20to%20establish%20age-%20and%20sex-specific%20reference%20intervals%20for%20serum%20concentrations%20of%20thyrotropin%20%28TSH%29%2C%20free%20triiodothyronine%20%28fT3%29%2C%20and%20free%20thyroxine%20%28fT4%29%20in%20healthy%20children%20and%20adolescents.%20Additionally%2C%20we%20investigated%20the%20association%20of%20TSH%2C%20fT3%2C%20and%20fT4%20with%20putative%20influencing%20factors%2C%20such%20as%20sex%2C%20body%20mass%20index%20%28BMI%29%2C%20and%20puberty.%20Methods%3A%20A%20total%20of%209404%20blood%20serum%20samples%20from%203140%20children%20and%20adolescents%20without%20thyroid%20affecting%20diseases%20were%20included%20in%20determining%20TSH%2C%20fT3%2C%20and%20fT4%20levels%20and%20age-%20and%20sex-specific%20reference%20ranges.%20To%20investigate%20the%20association%20of%20TSH%2C%20fT3%2C%20and%20fT4%20with%20age%2C%20sex%2C%20weight%20status%2C%20and%20the%20role%20of%20puberty-based%20changes%2C%20the%20hormone%20levels%20and%20BMI%20values%20were%20converted%20to%20standard%20deviation%20scores%20%28SDS%29.%20Results%3A%20In%20general%2C%20TSH%2C%20fT3%2C%20and%20fT4%20were%20found%20to%20be%20age-%20and%20sex-dependent.%20Puberty%20was%20accompanied%20by%20decreased%20TSH%2C%20decreased%20fT3%20with%20a%20temporary%20peak%20in%20males%2C%20and%20a%20temporary%20nadir%20of%20fT4%20in%20Tanner%20stage%203%20for%20both%20sexes.%20BMI-SDS%20was%20positively%20associated%20with%20TSH-SDS%20%28%5Cu03b2%5Cu2009%3D%5Cu20090.081%2C%20p%5Cu2009%3C%5Cu20090.001%29%3B%20the%20effect%20was%20more%20pronounced%20in%20overweight%20subjects%20%28%5Cu03b2%5Cu2009%3D%5Cu20090.142%2C%20p%5Cu2009%3C%5Cu20090.01%29%20and%20insignificantly%20negative%20in%20underweight%20subjects%20%28%5Cu03b2%5Cu2009%3D%5Cu2009-0.047%2C%20p%5Cu2009%3E%5Cu20090.05%29.%20BMI-SDS%20was%20positively%20associated%20with%20fT3-SDS%20%28%5Cu03b2%5Cu2009%3D%5Cu20090.066%2C%20p%5Cu2009%3C%5Cu20090.001%29%20and%20negatively%20associated%20with%20fT4-SDS%20%28%5Cu03b2%5Cu2009%3D%5Cu2009-0.135%2C%20p%5Cu2009%3C%5Cu20090.001%29%2C%20with%20the%20effect%20insignificantly%20less%20negative%20in%20overweight%20children%20%28%5Cu03b2%5Cu2009%3D%5Cu2009-0.055%2C%20p%5Cu2009%3E%5Cu20090.05%29.%20Conclusions%3A%20Age-%20and%20sex-specific%20reference%20intervals%20are%20important%20for%20the%20interpretation%20of%20measurements%20of%20TSH%2C%20fT3%2C%20and%20fT4%20in%20children%20and%20adolescents.%20Influencing%20factors%20such%20as%20BMI%20and%20puberty%20should%20be%20taken%20into%20consideration%20when%20using%20measurements%20of%20TSH%20and%20thyroid%20hormones%20in%20the%20diagnosis%2C%20treatment%2C%20and%20monitoring%20of%20thyroid%20diseases.%20Clinical%20Trial%20Registration%20number%3A%20NCT02550236.%22%2C%22date%22%3A%222021-08%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1089%5C%2Fthy.2020.0780%22%2C%22ISSN%22%3A%221557-9077%22%2C%22url%22%3A%22http%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1089%5C%2Fthy.2020.0780%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222024-06-21T10%3A23%3A41Z%22%7D%7D%2C%7B%22key%22%3A%22U9X95DPA%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Kempf%20et%20al.%22%2C%22parsedDate%22%3A%222021-06%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EKempf%2C%20Elena%2C%20Mandy%20Vogel%2C%20Tim%20Vogel%2C%20J%26%23xFC%3Brgen%20Kratzsch%2C%20Kathrin%20Landgraf%2C%20Andreas%20K%26%23xFC%3Bhnapfel%2C%20Ruth%20Gausche%2C%20et%20al.%20%26%23x201C%3BDynamic%20Alterations%20in%20Linear%20Growth%20and%20Endocrine%20Parameters%20in%20Children%20with%20Obesity%20and%20Height%20Reference%20Values.%26%23x201D%3B%20%3Ci%3EEClinicalMedicine%3C%5C%2Fi%3E%2037%20%28June%202021%29%3A%20100977.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.eclinm.2021.100977%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.eclinm.2021.100977%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Dynamic%20Alterations%20in%20Linear%20Growth%20and%20Endocrine%20Parameters%20in%20Children%20with%20Obesity%20and%20Height%20Reference%20Values%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Elena%22%2C%22lastName%22%3A%22Kempf%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tim%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J%5Cu00fcrgen%22%2C%22lastName%22%3A%22Kratzsch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Kathrin%22%2C%22lastName%22%3A%22Landgraf%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andreas%22%2C%22lastName%22%3A%22K%5Cu00fchnapfel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ruth%22%2C%22lastName%22%3A%22Gausche%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Daniel%22%2C%22lastName%22%3A%22Gr%5Cu00e4fe%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Elena%22%2C%22lastName%22%3A%22Sergeyev%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Roland%22%2C%22lastName%22%3A%22Pf%5Cu00e4ffle%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Juraj%22%2C%22lastName%22%3A%22Stanik%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%5D%2C%22abstractNote%22%3A%22Background%5CnObesity%20can%20affect%20linear%20growth%20of%20children%20but%20there%20is%20uncertainty%20regarding%20the%20dynamics%20and%20potential%20causes.%5CnMethods%5CnIn%20the%20population-based%20LIFE%20Child%20and%20the%20obesity-enriched%20Leipzig%20Obesity%20Childhood%20cohorts%20%288%2C629%20children%2C%2037%2C493%20measurements%29%2C%20recruited%20from%201999%20to%202018%20in%20Germany%2C%20we%20compared%20height%2C%20growth%2C%20and%20endocrine%20parameters%20between%20normal-weight%20and%20children%20with%20obesity%20%280%5Cu201320%20years%29.%20Derived%20from%20the%20independent%20German%20CrescNet%20registry%20%2812%2C703%20children%29%20we%20generated%20height%20reference%20values%20specific%20for%20children%20with%20obesity%20%28data%20collected%20from%201999%20to%202020%29.%5CnFindings%5CnChildren%20with%20obesity%20were%20significantly%20taller%20than%20normal-weight%20peers%2C%20differing%20at%20maximum%20by%207%5Cu00b76%5Cu00a0cm%20%281%5Cu00b74%20height%2C%20standard%20deviation%20scores%20or%20SDS%29%20at%20age%206%5Cu20138%20years.%20Already%20at%20birth%2C%20children%20with%20obesity%20were%20slightly%20taller%20and%20thereafter%20had%20increased%20growth%20velocities%20by%20up%20to%201%5Cu00b72%5Cu00a0cm%5C%2Fyear.%20This%20growth%20acceleration%20was%20unrelated%20to%20parental%20height%2C%20but%20was%20accompanied%20by%20increased%20levels%20of%20insulin-like%20growth%20factor-1%20%28IGF-1%29%2C%20insulin%20and%20leptin.%20During%20puberty%2C%20children%20with%20obesity%20showed%20a%20catch-down%20in%20height%20SDS.%20The%20reduction%20in%20pubertal%20growth%20velocity%20by%20up%20to%2025%25%20coincided%20with%20a%20decrease%20in%20levels%20of%20IGF-1%20%28by%2017%25%29%20and%20testosterone%20%28by%2062%25%29%20in%20boys%20and%20estradiol%20%28by%2037%25%29%20in%20girls.%20We%20confirmed%20these%20alterations%20in%20growth%20in%20the%20independent%20CrescNet%20cohort%20and%20furthermore%20provide%20height%20reference%20values%20for%20children%20with%20obesity%20for%20open%20access.%5CnInterpretation%5CnDynamics%20of%20linear%20growth%20are%20altered%20distinctively%20in%20different%20developmental%20phases%20in%20children%20with%20obesity.%20Early%20emergence%20before%20other%20profound%20comorbidities%20implies%20predisposition%2C%20environmental%2C%20and%5C%2For%20endocrine%20factors%20affecting%20growth%20in%20early%20life.%20Height%20reference%20values%20for%20children%20with%20obesity%20may%20enhance%20the%20precision%20of%20clinical%20health%20surveillance.%5CnFunding%5CnGerman%20Research%20Foundation%2C%20German%20Diabetes%20Association%2C%20EU%2C%20ESF%2C%20ERDF%2C%20State%20of%20Saxony%2C%20ESPE%2C%20Hexal%2C%20Novo%20Nordisk%2C%20Pfizer%20Pharma.%22%2C%22date%22%3A%22June%2C%202021%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1016%5C%2Fj.eclinm.2021.100977%22%2C%22ISSN%22%3A%222589-5370%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.sciencedirect.com%5C%2Fscience%5C%2Farticle%5C%2Fpii%5C%2FS2589537021002571%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-12-31T14%3A24%3A55Z%22%7D%7D%2C%7B%22key%22%3A%22Q3I3H44N%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Truckenbrod%20et%20al.%22%2C%22parsedDate%22%3A%222021-05%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3ETruckenbrod%2C%20Carolin%2C%20Christof%20Meigen%2C%20Manuela%20Brandt%2C%20Mandy%20Vogel%2C%20Pablo%20Sanz%20Diez%2C%20Siegfried%20Wahl%2C%20Anne%20Jurkutat%2C%20and%20Wieland%20Kiess.%20%26%23x201C%3BLongitudinal%20Analysis%20of%20Axial%20Length%20Growth%20in%20a%20German%20Cohort%20of%20Healthy%20Children%20and%20Adolescents.%26%23x201D%3B%20%3Ci%3EOphthalmic%20%26amp%3B%20Physiological%20Optics%3A%20The%20Journal%20of%20the%20British%20College%20of%20Ophthalmic%20Opticians%20%28Optometrists%29%3C%5C%2Fi%3E%2041%2C%20no.%203%20%28May%202021%29%3A%20532%26%23×2013%3B40.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fopo.12817%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fopo.12817%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Longitudinal%20Analysis%20of%20Axial%20Length%20Growth%20in%20a%20German%20Cohort%20of%20Healthy%20Children%20and%20Adolescents%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Carolin%22%2C%22lastName%22%3A%22Truckenbrod%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christof%22%2C%22lastName%22%3A%22Meigen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Manuela%22%2C%22lastName%22%3A%22Brandt%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Pablo%22%2C%22lastName%22%3A%22Sanz%20Diez%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Siegfried%22%2C%22lastName%22%3A%22Wahl%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anne%22%2C%22lastName%22%3A%22Jurkutat%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%5D%2C%22abstractNote%22%3A%22PURPOSE%3A%20To%20generate%20continuous%20growth%20curves%20for%20axial%20length%20%28AL%29%20in%20German%20children.%20We%20hypothesise%20that%20percentile%20curves%20of%20AL%20can%20be%20used%20as%20a%20predictive%20measure%20of%20myopia.%5CnMETHODS%3A%20In%20this%20longitudinal%20and%20cross-sectional%20LIFE%20Child%20Study%2C%20children%27s%20non-cycloplegic%20refraction%20data%20was%20collected%20using%20the%20Zeiss%20i.Profiler%20plus%20while%20AL%20was%20measured%20using%20the%20Haag-Streit%20Lenstar.%20Reference%20growth%20curves%20were%20estimated%20as%20a%20continuous%20non-parametric%20function%20of%20age.%5CnRESULTS%3A%20Data%20from%204511%20visits%20of%201965%20participants%20%281021%20boys%20and%20944%20girls%29%20between%203%20and%2018%5Cu00a0years%20of%20age%20were%20analysed.%20For%20all%20ages%20and%20percentiles%2C%20the%20estimated%20AL%20was%20higher%20in%20boys%20than%20girls.%20AL%20differences%20between%20boys%20and%20girls%20were%20most%20pronounced%20in%20the%2098th%20percentile%20at%203%5Cu00a0years%20of%20age%2C%20being%200.93%5Cu00a0mm%20longer%20eyes%20in%20boys.%20This%20difference%20decreased%20to%200.21%5Cu00a0mm%20at%2018%5Cu00a0years%20of%20age.%20While%20the%20lower%20percentiles%20of%20AL%20reach%20their%20final%20value%20around%20age%2013%2C%20the%2050th%20percentile%20was%20still%20increasing%20by%200.05%5Cu00a0mm%20per%20year%20until%20the%20end%20of%20the%20observation%20period.%20While%2C%20in%20general%2C%20children%20with%20longer%20eyes%20are%20more%20likely%20to%20develop%20myopia%2C%20this%20relationship%20is%20weaker%20between%20the%20ages%20of%205%20and%208.%5CnCONCLUSION%3A%20The%20LIFE%20Child%20Study%20data%20provides%20European%20AL%20data.%20In%20both%20Germany%20and%20China%2C%20AL%20has%20comparable%20growth%20rates%20when%20the%20baseline%20ALs%20are%20compared%20as%20percentiles.%20Thus%2C%20percentile%20curves%20of%20AL%20can%20be%20used%20as%20a%20predictive%20measure%20for%20the%20likelihood%20of%20developing%20as%20well%20as%20the%20progression%20of%20myopia.%22%2C%22date%22%3A%222021-05%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1111%5C%2Fopo.12817%22%2C%22ISSN%22%3A%221475-1313%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Forgid.org%5C%2F10.1111%5C%2Fopo.12817%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-24T13%3A30%3A03Z%22%7D%7D%2C%7B%22key%22%3A%226VMFZRL2%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Kreusler%20et%20al.%22%2C%22parsedDate%22%3A%222021-02%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EKreusler%2C%20Paulina%2C%20Mandy%20Vogel%2C%20Anja%20Willenberg%2C%20Ronny%20Baber%2C%20Yvonne%20Dietz%2C%20Antje%20K%26%23xF6%3Brner%2C%20Uta%20Ceglarek%2C%20and%20Wieland%20Kiess.%20%26%23x201C%3BFolate%20and%20Cobalamin%20Serum%20Levels%20in%20Healthy%20Children%20and%20Adolescents%20and%20Their%20Association%20with%20Age%2C%20Sex%2C%20Bmi%20and%20Socioeconomic%20Status.%26%23x201D%3B%20%3Ci%3ENutrients%3C%5C%2Fi%3E%2013%2C%20no.%202%20%28February%202021%29.%20%3Ca%20class%3D%27zp-ItemURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Fnu13020546%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Fnu13020546%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Folate%20and%20Cobalamin%20Serum%20Levels%20in%20Healthy%20Children%20and%20Adolescents%20and%20Their%20Association%20with%20Age%2C%20Sex%2C%20Bmi%20and%20Socioeconomic%20Status%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Paulina%22%2C%22lastName%22%3A%22Kreusler%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anja%22%2C%22lastName%22%3A%22Willenberg%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ronny%22%2C%22lastName%22%3A%22Baber%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Yvonne%22%2C%22lastName%22%3A%22Dietz%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Uta%22%2C%22lastName%22%3A%22Ceglarek%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%5D%2C%22abstractNote%22%3A%22This%20study%20proposes%20age-%20and%20sex-specific%20percentiles%20for%20serum%20cobalamin%20and%20folate%2C%20and%20analyzes%20the%20effects%20of%20sex%2C%20age%2C%20body%20mass%20index%20%28BMI%29%2C%20and%20socioeconomic%20status%20%28SES%29%20on%20cobalamin%20and%20folate%20concentrations%20in%20healthy%20children%20and%20adolescents.%20In%20total%2C%204478%20serum%20samples%20provided%20by%20healthy%20participants%20%282%20months-18.0%20years%29%20in%20the%20LIFE%20%28Leipzig%20Research%20Centre%20for%20Civilization%20Diseases%29%20Child%20population-based%20cohort%20study%20between%202011%20and%202015%20were%20analyzed%20by%20electrochemiluminescence%20immunoassay%20%28ECLIA%29.%20Continuous%20age-and%20sex-related%20percentiles%20%282.5th%2C%2010th%2C%2050th%2C%2090th%2C%2097.5th%29%20were%20estimated%2C%20applying%20Cole%27s%20LMS%20method.%20In%20both%20sexes%2C%20folate%20concentrations%20decreased%20continuously%20with%20age%2C%20whereas%20cobalamin%20concentration%20peaked%20between%20three%20and%20seven%20years%20of%20age%20and%20declined%20thereafter.%20Female%20sex%20was%20associated%20with%20higher%20concentrations%20of%20both%20vitamins%20in%2013-%20to%2018-year-olds%20and%20with%20higher%20folate%20levels%20in%20one-%20to%20five-year-olds.%20BMI%20was%20inversely%20correlated%20with%20concentrations%20of%20both%20vitamins%2C%20whilst%20SES%20positively%20affected%20folate%20but%20not%20cobalamin%20concentrations.%20To%20conclude%2C%20in%20the%20assessment%20of%20cobalamin%20and%20folate%20status%2C%20the%20age-%20and%20sex-dependent%20dynamic%20of%20the%20respective%20serum%20concentrations%20must%20be%20considered.%20While%20BMI%20is%20a%20determinant%20of%20both%20vitamin%20concentrations%2C%20SES%20is%20only%20associated%20with%20folate%20concentrations.%22%2C%22date%22%3A%222021-02%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.3390%5C%2Fnu13020546%22%2C%22ISSN%22%3A%222072-6643%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Fnu13020546%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222024-04-10T08%3A01%3A32Z%22%7D%7D%2C%7B%22key%22%3A%22CZ58MVPA%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Wallborn%20et%20al.%22%2C%22parsedDate%22%3A%222020-05%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EWallborn%2C%20Tillmann%2C%20Mandy%20Vogel%2C%20Antje%20Kneuer%2C%20Michael%20Thamm%2C%20Katalin%20Dittrich%2C%20Wieland%20Kiess%2C%20and%20J%26%23xFC%3Brgen%20Kratzsch.%20%26%23x201C%3BSpot%20Urine%20Iodine%20Levels%20Below%20the%20Who%20Recommendation%20Are%20Not%20Related%20to%20Impaired%20Thyroid%20Function%20in%20Healthy%20Children%20and%20Adolescents.%26%23x201D%3B%20%3Ci%3EEuropean%20Journal%20of%20Nutrition%3C%5C%2Fi%3E%2060%20%28May%202020%29%3A%20493%26%23×2013%3B502.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs00394-020-02268-3%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs00394-020-02268-3%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Spot%20Urine%20Iodine%20Levels%20Below%20the%20Who%20Recommendation%20Are%20Not%20Related%20to%20Impaired%20Thyroid%20Function%20in%20Healthy%20Children%20and%20Adolescents%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tillmann%22%2C%22lastName%22%3A%22Wallborn%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22Kneuer%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Michael%22%2C%22lastName%22%3A%22Thamm%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Katalin%22%2C%22lastName%22%3A%22Dittrich%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J%5Cu00fcrgen%22%2C%22lastName%22%3A%22Kratzsch%22%7D%5D%2C%22abstractNote%22%3A%22PURPOSE%3A%20Iodine%20deficiency%20in%20childhood%20and%20adolescence%20may%20lead%20to%20later%20thyroid%20dysfunction%2C%20stunted%20growth%20and%20cognitive%20impairment.%20The%20World%20Health%20Organization%20%28WHO%29%20has%20issued%20recommended%20age-dependent%20urine%20iodine%20concentration%20targets%2C%20but%20a%20critical%20threshold%20beyond%20which%20clinical%20sequelae%20are%20to%20be%20expected%20remains%20undefined.%20Our%20study%20aimed%20to%20investigate%20spot%20urine%20iodine%20concentration%20in%20a%20typical%20Central%20European%20cohort%20of%20children%20and%20adolescents%2C%20and%20consider%20the%20implications%20of%20these%20values%20in%20regard%20to%20laboratory%20parameters%20for%20evaluating%20thyroid%20function.%5CnMETHODS%3A%20Using%20the%20Sandell-Kolthoff%20method%2C%20spot%20urine%20iodine%20concentration%20was%20measured%20cross-sectionally%20from%201802%20healthy%20children%20and%20adolescent%20in%20the%20age%20range%20of%200.25-18%5Cu00a0years%20within%20the%20LIFE-Child%20epidemiological%20study%20based%20in%20and%20around%20the%20city%20of%20Leipzig%20%28Germany%29.%20Additionally%2C%20serum%20thyroid%20biomarkers%20of%20these%20subjects%20were%20measured%20and%20correlated%20to%20urine%20iodine%20levels.%5CnRESULTS%3A%20In%20our%20cohort%2C%2061.39%25%20of%20boys%20and%2065.91%25%20of%20girls%20had%20an%20iodine%20level%20of%20%3C%5Cu2009100%5Cu00a0%5Cu00b5g%5C%2FL%20%2857%25%2C%2067%25%2C%2065%25%20of%20the%20age%20groups%200-5%2C%206-12%20and%2013-18%5Cu00a0years%29%2C%20the%20median%20iodine%20excretion%20was%2086%5Cu00a0%5Cu00b5g%5C%2FL%20in%20boys%20and%2080%5Cu00a0%5Cu00b5g%5C%2FL%20in%20girls.%20The%20iodine%20levels%20revealed%20no%20significant%20correlation%20with%20the%20thyroid%20biomarkers%20TSH%2C%20FT4%20and%20FT3.%20Moreover%2C%20iodine%20values%20revealed%20no%20correlation%20with%20levels%20of%20antibodies%20against%20thyroid%20peroxidase%20or%20thyroglobulin.%5CnCONCLUSION%3A%20In%20our%20cohort%20of%20children%20and%20adolescents%2C%20the%20relatively%20high%20number%20of%20iodine%20levels%20below%20the%20WHO%20recommendation%20appears%20not%20to%20be%20related%20to%20clinical%20or%20subclinical%20thyroid%20diseases%20in%20the%20respective%20participants.%22%2C%22date%22%3A%22May%2C%202020%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1007%5C%2Fs00394-020-02268-3%22%2C%22ISSN%22%3A%221436-6215%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-07T07%3A01%3A19Z%22%7D%7D%2C%7B%22key%22%3A%22BYWNMEMC%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Truckenbrod%20et%20al.%22%2C%22parsedDate%22%3A%222020-03%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3ETruckenbrod%2C%20Carolin%2C%20Christof%20Meigen%2C%20Manuela%20Brandt%2C%20Mandy%20Vogel%2C%20Siegfried%20Wahl%2C%20Anne%20Jurkutat%2C%20and%20Wieland%20Kiess.%20%26%23x201C%3BReference%20Curves%20for%20Refraction%20in%20a%20German%20Cohort%20of%20Healthy%20Children%20and%20Adolescents.%26%23x201D%3B%20%3Ci%3EPLOS%20ONE%3C%5C%2Fi%3E%2015%2C%20no.%203%20%28March%202020%29%3A%20e0230291.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1371%5C%2Fjournal.pone.0230291%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1371%5C%2Fjournal.pone.0230291%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Reference%20Curves%20for%20Refraction%20in%20a%20German%20Cohort%20of%20Healthy%20Children%20and%20Adolescents%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Carolin%22%2C%22lastName%22%3A%22Truckenbrod%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christof%22%2C%22lastName%22%3A%22Meigen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Manuela%22%2C%22lastName%22%3A%22Brandt%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Siegfried%22%2C%22lastName%22%3A%22Wahl%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anne%22%2C%22lastName%22%3A%22Jurkutat%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%5D%2C%22abstractNote%22%3A%22Purpose%20Percentile%20curves%20of%20refractive%20development%20for%20German%20children%20were%20generated.%20We%20hypothesize%20that%20refraction%20in%20children%20in%20central%20Europe%20might%20differ%20from%20data%20in%20central%20Asia.%20Methods%20Non-cycloplegic%20refraction%20was%20measured%20using%20the%20ZEISS%20i.Profiler%20plus%20%28Carl%20Zeiss%20Vision%20GmbH%2C%20Germany%29%20in%201999%20children%2C%20of%20which%20were%201046%20male%20and%20953%20female%2C%20aged%203%20to%2018%20years.%20Reference%20curves%20were%20calculated%20with%20the%20R-package%20GAMLSS%20as%20continuous%20function%20of%20age.%20Results%20There%20were%20only%20little%20differences%20for%20all%20centiles%20between%20the%20genders%20at%203%20years%20and%20a%20general%20trend%20towards%20more%20myopia%20with%20increasing%20age.%20For%20the%2097th%20centile%20and%20the%203rd%20centile%2C%20girls%20showed%20higher%20myopia%5C%2F%20less%20hyperopia%20than%20boys.%20Between%20the%20age%20of%203%20and%2018%2C%20the%20median%20refraction%20became%20-0.68%20D%20and%20-0.74%20D%20more%20myopic%20for%20boys%20and%20girls%2C%20respectively.%20At%20the%20same%20time%2C%20the%2097th%20centile%20for%20boys%20changed%20%2B0.29%20D%20towards%20hyperopia%20and%20in%20girls%20-0.52%20D%20towards%20myopia.%20A%20general%20myopic%20trend%20was%20seen%20in%20the%203rd%20centile%2C%20which%20was%20-2.46%20D%20for%20boys%20and%20-2.98%20D%20for%20girls.%20For%20both%20genders%2C%20the%20median%20became%20less%20than%20zero%20at%20the%20age%20of%2010%20years%20but%20did%20not%20become%20myopic%20%28less%20than%20-0.5%20D%29%20up%20to%20the%20age%20of%2018.%20Conclusion%20Our%20analysis%20presents%20the%20first%20reference%20curve%20for%20refraction%20in%20central%20Europe.%20In%20comparison%20to%20data%20from%20China%20and%20Korea%2C%20there%20is%20only%20little%20difference%20at%20the%20age%20of%205%20years%20in%20all%20centiles%20which%20then%20increases%20continuously.%20For%20all%20ethnicities%2C%20a%20trend%20towards%20myopia%20with%20increasing%20age%20could%20be%20observed%2C%20but%20myopia%20progression%20is%20much%20higher%20in%20China%20and%20Korea%20than%20in%20Germany.%20The%20most%20marked%20differences%20can%20be%20seen%20in%20the%20lower%20centiles.%20Further%20investigations%20should%20clarify%20whether%20commencement%20of%20preschool%20activities%20with%20prolonged%20near-work%20initiates%20the%20divergence%20in%20refractive%20development.%22%2C%22date%22%3A%22Mar%2C%202020%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1371%5C%2Fjournal.pone.0230291%22%2C%22ISSN%22%3A%221932-6203%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fjournals.plos.org%5C%2Fplosone%5C%2Farticle%3Fid%3D10.1371%5C%2Fjournal.pone.0230291%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-07T07%3A01%3A22Z%22%7D%7D%2C%7B%22key%22%3A%22TEN9EGD3%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Geserick%20et%20al.%22%2C%22parsedDate%22%3A%222020%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EGeserick%2C%20M.%2C%20M.%20Vogel%2C%20F.%20Eckelt%2C%20M.%20Schlingmann%2C%20A.%20Hiemisch%2C%20R.%20Baber%2C%20J.%20Thiery%2C%20A.%20K%26%23xF6%3Brner%2C%20W.%20Kiess%2C%20and%20J.%20Kratzsch.%20%26%23x201C%3BChildren%20and%20Adolescents%20with%20Obesity%20Have%20Reduced%20Serum%20Bone%20Turnover%20Markers%20and%2025-Hydroxyvitamin%20D%20but%20Increased%20Parathyroid%20Hormone%20Concentrations%20%26%23×2013%3B%20Results%20Derived%20from%20New%20Pediatric%20Reference%20Ranges.%26%23x201D%3B%20%3Ci%3EBone%3C%5C%2Fi%3E%20132%20%282020%29%3A%20115124.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.bone.2019.115124%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.bone.2019.115124%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Children%20and%20Adolescents%20with%20Obesity%20Have%20Reduced%20Serum%20Bone%20Turnover%20Markers%20and%2025-Hydroxyvitamin%20D%20but%20Increased%20Parathyroid%20Hormone%20Concentrations%20%5Cu2013%20Results%20Derived%20from%20New%20Pediatric%20Reference%20Ranges%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22M.%22%2C%22lastName%22%3A%22Geserick%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22M.%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22F.%22%2C%22lastName%22%3A%22Eckelt%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22M.%22%2C%22lastName%22%3A%22Schlingmann%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22A.%22%2C%22lastName%22%3A%22Hiemisch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22R.%22%2C%22lastName%22%3A%22Baber%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J.%22%2C%22lastName%22%3A%22Thiery%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22A.%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22W.%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J.%22%2C%22lastName%22%3A%22Kratzsch%22%7D%5D%2C%22abstractNote%22%3A%22Background%3A%20We%20aimed%20to%20establish%20age-%20and%20gender-specific%20reference%20ranges%20for%20concentrations%20of%20the%20bone%20markers%20osteocalcin%20%28OC%29%2C%20procollagen%20type%201%20N-propeptides%20%28PINP%29%20and%20carboxy-terminal%20cross-linking%20telopeptide%20of%20type%201%20collagen%20%28CTX-I%29%20as%20well%20as%20for%20the%20calciotropic%20hormones%2025-hydroxyvitamin%20D%20%5B25%28OH%29D%5D%20and%20parathyroid%20hormone%20%28PTH%29%20in%20healthy%20infants%2C%20children%20and%20adolescents.%20In%20addition%2C%20the%20effect%20of%20age%2C%20gender%2C%20puberty%20and%20body%20mass%20index%20%28BMI%29%20on%20bone%20markers%20was%20investigated.%5CnMethods%3A%202416%20healthy%20subjects%20%285714%20blood%20withdrawals%29%2C%20aged%203%20months%20to%2017%20years%2C%20were%20included%20to%20estimate%20the%20age-%20and%20gender-dependence%20of%20reference%20ranges.%20Subsequently%2C%20measured%20values%20of%20the%20biomarkers%20were%20transformed%20to%20standard%20deviation%20scores%20%28SDS%29%20and%20their%20associations%20with%20age%2C%20gender%20and%20puberty%20were%20analyzed.%20Bone%20marker-SDS%20values%20of%20the%20reference%20cohort%20were%20compared%20with%20an%20obese%20cohort%20%28n%20%3D%20317%20and%20489%20blood%20withdrawals%29%20to%20analyze%20the%20effect%20of%20BMI.%5CnResults%3A%20OC%2C%20PINP%20and%20CTX-I%20showed%20a%20distinct%20age-%20and%20gender-dependence%20with%20peak%20levels%20at%2010%20to%2011%20years%20%28girls%2C%20Tanner%203%29%20and%2013%20years%20%28boys%2C%20Tanner%203%5Cu20134%29.%20Children%20with%20obesity%20had%20significantly%20lower%20SDS%20levels%20for%20OC%20%28%5Cu22120.44%29%2C%20PINP%20%28%5Cu22120.27%29%2C%20CTX-I%20%28%5Cu22120.33%29%2C%2025%28OH%29D%20%28%5Cu22120.43%29%20and%20higher%20SDS%20levels%20for%20PTH%20%28%2B0.44%29%20than%20the%20reference%20cohort.%5CnConclusions%3A%20OC%2C%20PINP%20and%20CTX-I%20vary%20with%20age%2C%20gender%20and%20pubertal%20stage.%20The%20body%20weight%20status%20has%20to%20be%20considered%20in%20the%20interpretation%20of%20pediatric%20OC%2C%20PINP%2C%20CTX-I%2C%2025%28OH%29D%20and%20PTH%20levels.%20Consequences%20of%20childhood%20obesity%20on%20bone%20health%20should%20be%20carefully%20investigated%20in%20long-term%20studies.%22%2C%22date%22%3A%2203%5C%2F2020%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1016%5C%2Fj.bone.2019.115124%22%2C%22ISSN%22%3A%2287563282%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Flinkinghub.elsevier.com%5C%2Fretrieve%5C%2Fpii%5C%2FS8756328219304181%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222024-01-02T15%3A33%3A44Z%22%7D%7D%2C%7B%22key%22%3A%22YMB2N7CQ%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Dathan-Stumpf%20et%20al.%22%2C%22parsedDate%22%3A%222019-12%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EDathan-Stumpf%2C%20Anne%2C%20Mandy%20Vogel%2C%20Alexander%20Jank%2C%20Joachim%20Thiery%2C%20Wieland%20Kiess%2C%20and%20Holger%20Stepan.%20%26%23x201C%3BReference%20Intervals%20of%20Serum%20Lipids%20in%20the%20Second%20and%20Third%20Trimesters%20of%20Pregnancy%20in%20a%20Caucasian%20Cohort%3A%20The%20Life%20Child%20Study.%26%23x201D%3B%20%3Ci%3EArchives%20of%20Gynecology%20and%20Obstetrics%3C%5C%2Fi%3E%20300%2C%20no.%206%20%28December%202019%29%3A%201531%26%23×2013%3B39.%20%3Ca%20class%3D%27zp-ItemURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs00404-019-05342-2%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs00404-019-05342-2%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Reference%20Intervals%20of%20Serum%20Lipids%20in%20the%20Second%20and%20Third%20Trimesters%20of%20Pregnancy%20in%20a%20Caucasian%20Cohort%3A%20The%20Life%20Child%20Study%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anne%22%2C%22lastName%22%3A%22Dathan-Stumpf%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Alexander%22%2C%22lastName%22%3A%22Jank%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Joachim%22%2C%22lastName%22%3A%22Thiery%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Holger%22%2C%22lastName%22%3A%22Stepan%22%7D%5D%2C%22abstractNote%22%3A%22The%20study%20aimed%20to%20establish%20reference%20intervals%20for%20serum%20lipids%20and%20apolipoproteins%20in%20pregnant%20women%20depending%20on%20trimester%20and%20parity%2C%20and%20to%20investigate%20the%20influence%20of%20various%20factors%20on%20lipid%20and%20apolipoprotein%20concentrations.%22%2C%22date%22%3A%222019-12%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1007%5C%2Fs00404-019-05342-2%22%2C%22ISSN%22%3A%221432-0711%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs00404-019-05342-2%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222024-03-27T11%3A45%3A53Z%22%7D%7D%2C%7B%22key%22%3A%22JDTTKV5E%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Berger%20et%20al.%22%2C%22parsedDate%22%3A%222019-07%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EBerger%2C%20Thomas%2C%20Thomas%20Peschel%2C%20Mandy%20Vogel%2C%20Diana%20Pietzner%2C%20Tanja%20Poulain%2C%20Anne%20Jurkutat%2C%20Sylvia%20Meuret%2C%20Christoph%20Engel%2C%20Wieland%20Kiess%2C%20and%20Michael%20Fuchs.%20%26%23x201C%3BSpeaking%20Voice%20in%20Children%20and%20Adolescents%3A%20Normative%20Data%20and%20Associations%20with%20Bmi%2C%20Tanner%20Stage%2C%20and%20Singing%20Activity.%26%23x201D%3B%20%3Ci%3EJournal%20of%20Voice%3C%5C%2Fi%3E%2033%2C%20no.%204%20%28July%202019%29%3A%20580.e21-580.e30.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.jvoice.2018.01.006%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.jvoice.2018.01.006%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Speaking%20Voice%20in%20Children%20and%20Adolescents%3A%20Normative%20Data%20and%20Associations%20with%20Bmi%2C%20Tanner%20Stage%2C%20and%20Singing%20Activity%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Thomas%22%2C%22lastName%22%3A%22Berger%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Thomas%22%2C%22lastName%22%3A%22Peschel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Diana%22%2C%22lastName%22%3A%22Pietzner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anne%22%2C%22lastName%22%3A%22Jurkutat%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Sylvia%22%2C%22lastName%22%3A%22Meuret%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christoph%22%2C%22lastName%22%3A%22Engel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Michael%22%2C%22lastName%22%3A%22Fuchs%22%7D%5D%2C%22abstractNote%22%3A%22Objectives%5CnThe%20aim%20of%20this%20study%20was%20to%20establish%20normative%20data%20concerning%20the%20speaking%20voice%20of%20children%20and%20adolescents%20for%20clinical%20diagnostics.%5CnStudy%20Design%5CnPopulation-based%20mixed%20cross-sectional%20and%20longitudinal%20childhood%20cohort%20study.%5CnMethods%5CnNormative%20data%20measuring%20the%20speaking%20voice%20profile%20of%201352%20male%20and%201274%20female%20participants%20aged%206%20to%2017%20years%20were%20collected.%20To%20evaluate%20the%20voice%20range%2C%20five%20different%20intensity%20levels%20as%20the%20quietest%20voicing%20speaking%20voice%20%28Level%20I%29%2C%20conversational%20voice%20%28Level%20II%29%2C%20classroom%20voice%20%28Level%20III%29%2C%20shouting%20voice%20%28Level%20IV%29%2C%20and%20again%20the%20quietest%20speaking%20voice%20%28Level%20V%29%20were%20investigated.%20Multivariable%20analyses%20were%20performed%20to%20describe%20the%20effects%20of%20body%20mass%20index%2C%20Tanner%20stage%2C%20and%20singing%20activity%20on%20the%20outcome%20variables.%5CnResults%5CnA%20clear%20distinction%20in%20frequencies%20and%20sound%20pressure%20levels%20between%20the%20five%20different%20voice%20levels%20can%20be%20found%20in%20both%20genders.%20In%20females%20the%20mean%20fundamental%20frequency%20of%20the%20conversational%20voice%20lowers%20from%20223.3%20to%20205.8%5Cu2009Hz.%20In%20male%20participants%20it%20lowers%20from%20223.3%20to%20102.3%5Cu2009Hz.%20The%20most%20substantial%20decrease%20in%20the%20fundamental%20frequency%20of%20the%20speaking%20voice%20in%20boys%20occurs%20at%2013.5%20years.%20Girls%20show%20an%20almost%20continuous%20decline%20in%20their%20fundamental%20frequency.%20Only%20the%20Tanner%20stage%20showed%20significant%20positive%20relationships%20with%20the%20grade%20of%20lowering%20of%20the%20fundamental%20frequency%20in%20both%20sexes.%5CnConclusions%5CnIt%20was%20shown%20that%20the%20investigation%20of%20the%20speaking%20voice%20using%20predefined%20intensity-levels%20represents%20a%20feasible%20examination%20for%20children%20and%20adolescents.%20This%20study%20provides%20reference%20data%20on%20the%20range%20and%20age-adjusted%20normative%20values%20of%20the%20speaking%20voice.%22%2C%22date%22%3A%22July%2C%202019%22%2C%22language%22%3A%22%22%2C%22DOI%22%3A%2210.1016%5C%2Fj.jvoice.2018.01.006%22%2C%22ISSN%22%3A%220892-1997%22%2C%22url%22%3A%22http%3A%5C%2F%5C%2Fwww.sciencedirect.com%5C%2Fscience%5C%2Farticle%5C%2Fpii%5C%2FS0892199717304186%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-23T10%3A27%3A14Z%22%7D%7D%2C%7B%22key%22%3A%22Z5TGN7TI%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Kratzsch%20et%20al.%22%2C%22parsedDate%22%3A%222019-06%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EKratzsch%2C%20J.%2C%20R.%20Kolm%2C%20A.%20Hoppe%2C%20P.%20Dilba%2C%20A.%20K%26%23xF6%3Brner%2C%20K.%20Wirkner%2C%20A.%20Hiemisch%2C%20and%20W.%20Kiess.%20%26%23x201C%3BReference%20Ranges%20for%20the%20Elecsys%26%23xAE%3B%20IGF-1%20and%20IGFBP-3%20Immunoassays%3A%20Effects%20of%20Age%2C%20Gender%20and%20Pubertal%20Stage.%26%23x201D%3B%20%3Ci%3EClinica%20Chimica%20Acta%3C%5C%2Fi%3E%20493%20%28June%202019%29%3A%20S319.%20%3Ca%20class%3D%27zp-ItemURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.cca.2019.03.694%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.cca.2019.03.694%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Reference%20ranges%20for%20the%20Elecsys%5Cu00ae%20IGF-1%20and%20IGFBP-3%20immunoassays%3A%20Effects%20of%20age%2C%20gender%20and%20pubertal%20stage%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J.%22%2C%22lastName%22%3A%22Kratzsch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22R.%22%2C%22lastName%22%3A%22Kolm%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22A.%22%2C%22lastName%22%3A%22Hoppe%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22P.%22%2C%22lastName%22%3A%22Dilba%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22A.%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22K.%22%2C%22lastName%22%3A%22Wirkner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22A.%22%2C%22lastName%22%3A%22Hiemisch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22W.%22%2C%22lastName%22%3A%22Kiess%22%7D%5D%2C%22abstractNote%22%3A%22%22%2C%22date%22%3A%222019-06%22%2C%22language%22%3A%22%22%2C%22DOI%22%3A%2210.1016%5C%2Fj.cca.2019.03.694%22%2C%22ISSN%22%3A%22%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.cca.2019.03.694%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-24T09%3A14%3A16Z%22%7D%7D%2C%7B%22key%22%3A%22L77AIQZE%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22R%5Cu00f6nnecke%20et%20al.%22%2C%22parsedDate%22%3A%222019-03%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3ER%26%23xF6%3Bnnecke%2C%20Elisa%2C%20Mandy%20Vogel%2C%20Sarah%20Bussler%2C%20Nico%20Grafe%2C%20Anne%20Jurkutat%2C%20Maike%20Schlingmann%2C%20Antje%20Koerner%2C%20and%20Wieland%20Kiess.%20%26%23x201C%3BAge-%20and%20Sex-Related%20Percentiles%20of%20Skinfold%20Thickness%2C%20Waist%20and%20Hip%20Circumference%2C%20Waist-to-Hip%20Ratio%20and%20Waist-to-Height%20Ratio%3A%20Results%20from%20a%20Population-Based%20Pediatric%20Cohort%20in%20Germany%20%28LIFE%20Child%29.%26%23x201D%3B%20%3Ci%3EObesity%20Facts%3C%5C%2Fi%3E%2012%2C%20no.%201%20%28March%202019%29%3A%2025%26%23×2013%3B39.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1159%5C%2F000494767%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1159%5C%2F000494767%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Age-%20and%20Sex-Related%20Percentiles%20of%20Skinfold%20Thickness%2C%20Waist%20and%20Hip%20Circumference%2C%20Waist-to-Hip%20Ratio%20and%20Waist-to-Height%20Ratio%3A%20Results%20from%20a%20Population-Based%20Pediatric%20Cohort%20in%20Germany%20%28LIFE%20Child%29%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Elisa%22%2C%22lastName%22%3A%22R%5Cu00f6nnecke%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Sarah%22%2C%22lastName%22%3A%22Bussler%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Nico%22%2C%22lastName%22%3A%22Grafe%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anne%22%2C%22lastName%22%3A%22Jurkutat%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Maike%22%2C%22lastName%22%3A%22Schlingmann%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22Koerner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%5D%2C%22abstractNote%22%3A%22BACKGROUND%3A%20Skinfold%20thickness%20%28ST%29%2C%20waist%20circumference%20%28WC%29%20and%20hip%20circumference%20%28HC%29%20measurements%20are%20simple%20methods%20for%20assessing%20fat%20tissue%20at%20defined%20body%20parts.%20We%20examined%20these%20parameters%20in%20a%20cohort%20of%20healthy%20children%20and%20adolescents%20in%20Leipzig.%20Our%20study%20provides%20current%20percentile%20curves%20for%20biceps%2C%20triceps%2C%20subscapular%20and%20iliac%20crest%20ST%2C%20plus%20WC%2C%20HC%2C%20waist-to-hip%20ratio%20and%20waist-to-height%20ratio.%5CnMETHODS%3A%206%2C344%20visits%20were%20recorded%20involving%202%2C363%20individuals%20from%203%20to%2016%20years%20in%20age.%20Continuous%20age-%20and%20gender-related%20percentiles%20%283rd%2C%2010th%2C%20median%2C%2090th%2C%2097th%20percentiles%29%20were%20estimated%20using%20Cole%27s%20LMS%20method.%5CnRESULTS%3A%20For%20biceps%20and%20triceps%20ST%2C%20boys%20show%20a%20peak%20at%20the%20beginning%20of%20adolescence%20with%20a%20subsequent%20decrease%2C%20while%20percentile%20values%20among%20girls%20rise%20across%20the%20age%20range.%20Subscapular%20and%20iliac%20crest%20percentiles%20also%20show%20increasing%20curves%20with%20disproportionately%20high%20values%20for%20P90%20and%20P97.%20Boys%20show%20higher%20values%20of%20WC%2C%20girls%20have%20higher%20levels%20of%20HC.%20WC%20and%20HC%20median%20percentiles%20constantly%20increase%20in%20both%20sexes%20with%20a%20plateau%20at%20the%20age%20of%2016%20for%20girls.%5CnCONCLUSION%3A%20Trends%20for%20all%20parameters%20of%20body%20fat%20are%20in%20line%20with%20other%20national%20and%20international%20studies.%20Unlike%20the%20KiGGS%20study%2C%20our%20study%20provides%20circumference%20data%20across%20the%20whole%20of%20our%20age%20range%2C%20i.e.%20from%203%20to%2016%20years.%22%2C%22date%22%3A%22March%202019%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1159%5C%2F000494767%22%2C%22ISSN%22%3A%221662-4033%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222024-01-02T15%3A22%3A54Z%22%7D%7D%2C%7B%22key%22%3A%22HR6Q5R75%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Ziegelasch%20et%20al.%22%2C%22parsedDate%22%3A%222019-03%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EZiegelasch%2C%20Niels%2C%20Mandy%20Vogel%2C%20Eva%20M%26%23xFC%3Bller%2C%20Nadin%20Tremel%2C%20Anne%20Jurkutat%2C%20Markus%20L%26%23xF6%3Bffler%2C%20Nicolas%20Terliesner%2C%20et%20al.%20%26%23x201C%3BCystatin%20C%20Serum%20Levels%20in%20Healthy%20Children%20Are%20Related%20to%20Age%2C%20Gender%2C%20and%20Pubertal%20Stage.%26%23x201D%3B%20%3Ci%3EPediatric%20Nephrology%3C%5C%2Fi%3E%2034%2C%20no.%203%20%28March%202019%29%3A%20449%26%23×2013%3B57.%20https%3A%5C%2F%5C%2Fdoi.org%5C%2F%3Ca%20class%3D%27zp-ItemURL%27%20target%3D%27_blank%27%20href%3D%2710.1007%5C%2Fs00467-018-4087-z%27%3E10.1007%5C%2Fs00467-018-4087-z%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Cystatin%20C%20Serum%20Levels%20in%20Healthy%20Children%20Are%20Related%20to%20Age%2C%20Gender%2C%20and%20Pubertal%20Stage%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Niels%22%2C%22lastName%22%3A%22Ziegelasch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Eva%22%2C%22lastName%22%3A%22M%5Cu00fcller%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Nadin%22%2C%22lastName%22%3A%22Tremel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anne%22%2C%22lastName%22%3A%22Jurkutat%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Markus%22%2C%22lastName%22%3A%22L%5Cu00f6ffler%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Nicolas%22%2C%22lastName%22%3A%22Terliesner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Joachim%22%2C%22lastName%22%3A%22Thiery%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anja%22%2C%22lastName%22%3A%22Willenberg%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Katalin%22%2C%22lastName%22%3A%22Dittrich%22%7D%5D%2C%22abstractNote%22%3A%22BACKGROUND%3A%20This%20study%20aims%20to%20establish%20age-%20and%20gender-specific%20cystatin%20C%20%28CysC%29%20reference%20values%20for%20healthy%20infants%2C%20children%2C%20and%20adolescents%20and%20to%20relate%20them%20to%20pubertal%20stage%2C%20height%2C%20weight%2C%20and%20body%20mass%20index%20%28BMI%29.%5CnMETHODS%3A%20Serum%20CysC%20and%20creatinine%20levels%20of%206217%20fasting%2C%20morning%20venous%20blood%20samples%20from%202803%20healthy%20participants%20of%20the%20LIFE%20Child%20study%20%28age%203%5Cu00a0months%20to%2018%5Cu00a0years%29%20were%20analyzed%20by%20an%20immunoassay.%20Recruitment%20started%20in%202011%3B%201636%20participants%20provided%20at%20least%20one%20follow-up%20measurement.%20Percentiles%20for%20CysC%20were%20calculated.%20Age-%20and%20gender-related%20effects%20of%20height%2C%20weight%2C%20BMI%2C%20and%20puberty%20status%20were%20assessed%20through%20linear%20regression%20models.%5CnRESULTS%3A%20Over%20the%20first%202%5Cu00a0years%20of%20life%2C%20median%20CysC%20levels%20decrease%20depending%20on%20height%20%28%5Cu00df%5Cu2009%3D%5Cu2009-%5Cu20090.010%5Cu00a0mg%5C%2Fl%5C%2Fcm%2C%20p%5Cu2009%3C%5Cu20090.001%29%20and%20weight%20%28%5Cu00df%5Cu2009%3D%5Cu2009-%5Cu20090.033%5Cu00a0mg%5C%2Fl%5C%2Fkg%2C%20p%5Cu2009%3C%5Cu20090.001%29%20from%201.06%20to%200.88%5Cu00a0mg%5C%2Fl%20for%20males%20and%20from%201.04%20to%200.87%5Cu00a0mg%5C%2Fl%20for%20females.%20Following%20the%20second%5Cu00a0year%20of%20age%2C%20the%20levels%20remain%20stable%20for%20eight%20years.%20From%2011%20to%2014%5Cu00a0years%20of%20age%2C%20there%20is%20an%20increase%20of%20median%20CysC%20levels%20in%20males%20to%200.98%5Cu00a0mg%5C%2Fl%20and%20a%20decrease%20in%20females%20to%200.86%5Cu00a0mg%5C%2Fl.%20The%20change%20is%20associated%20with%20puberty%20%28%5Cu00df%5Cu2009%3D%5Cu20090.105%5Cu00a0mg%5C%2Fl%5C%2FTanner%20stage%2C%20p%5Cu2009%3C%5Cu20090.001%20in%20males%20and%20%5Cu00df%5Cu2009%3D%5Cu2009-%5Cu20090.093%5Cu00a0mg%5C%2Fl%5C%2FTanner%20stage%2C%20p%5Cu2009%3C%5Cu20090.01%20in%20females%29%20and%20in%20males%20with%20height%20%28%5Cu00df%5Cu2009%3D%5Cu20090.003%5Cu00a0mg%5C%2Fl%5C%2Fcm%2C%20p%5Cu2009%3C%5Cu20090.001%29.%5CnCONCLUSIONS%3A%20CysC%20levels%20depend%20on%20age%2C%20gender%2C%20and%20height%2C%20especially%20during%20infancy%20and%20puberty.%20We%20recommend%20the%20use%20of%20age-%20and%20gender-specific%20reference%20values%20for%20CysC%20serum%20levels%20for%20estimating%20kidney%20function%20in%20clinical%20practice.%22%2C%22date%22%3A%22March%202019%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1007%5C%2Fs00467-018-4087-z%22%2C%22ISSN%22%3A%221432-198X%22%2C%22url%22%3A%2210.1007%5C%2Fs00467-018-4087-z%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-07T07%3A01%3A19Z%22%7D%7D%2C%7B%22key%22%3A%22V73RESVM%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Bae%20et%20al.%22%2C%22parsedDate%22%3A%222019%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EBae%2C%20Yoon%20Ju%2C%20Robert%20Zeidler%2C%20Ronny%20Baber%2C%20Mandy%20Vogel%2C%20Kerstin%20Wirkner%2C%20Markus%20Loeffler%2C%20Uta%20Ceglarek%2C%20et%20al.%20%26%23x201C%3BReference%20Intervals%20of%20Nine%20Steroid%20Hormones%20Over%20the%20Life-Span%20Analyzed%20by%20Lc-Ms%5C%2FMs%3A%20Effect%20of%20Age%2C%20Gender%2C%20Puberty%2C%20and%20Oral%20Contraceptives.%26%23x201D%3B%20%3Ci%3EThe%20Journal%20of%20Steroid%20Biochemistry%20and%20Molecular%20Biology%3C%5C%2Fi%3E%20193%20%282019%29%3A%20105409.%20%3Ca%20class%3D%27zp-ItemURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.jsbmb.2019.105409%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.jsbmb.2019.105409%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Reference%20Intervals%20of%20Nine%20Steroid%20Hormones%20Over%20the%20Life-Span%20Analyzed%20by%20Lc-Ms%5C%2FMs%3A%20Effect%20of%20Age%2C%20Gender%2C%20Puberty%2C%20and%20Oral%20Contraceptives%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Yoon%20Ju%22%2C%22lastName%22%3A%22Bae%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Robert%22%2C%22lastName%22%3A%22Zeidler%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ronny%22%2C%22lastName%22%3A%22Baber%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Kerstin%22%2C%22lastName%22%3A%22Wirkner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Markus%22%2C%22lastName%22%3A%22Loeffler%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Uta%22%2C%22lastName%22%3A%22Ceglarek%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Joachim%22%2C%22lastName%22%3A%22Thiery%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Juergen%22%2C%22lastName%22%3A%22Kratzsch%22%7D%5D%2C%22abstractNote%22%3A%22New%20reference%20intervals%20need%20to%20be%20established%20for%20a%20new%20analytical%20method%20with%20improved%20sensitivity%20and%20specificity.%20We%20aimed%20to%20establish%20the%20new%20reference%20intervals%20from%20infancy%20to%20senescence%20of%20nine%20steroid%20hormones%20%28cortisol%2C%20cortisone%2C%20progesterone%2C%2017-hydroxyprogesterone%20%2817-OHP%29%2C%20androstenedione%2C%20testosterone%2C%20estradiol%2C%20DHEAS%2C%20and%20aldosterone%29%20for%20LC-MS%5C%2FMS%20method.%20Serum%20samples%20from%204678%20reference%20individuals%20%28age%20range%3A%200.3-79%20years%29%20were%20measured%20with%20LC-MS%5C%2FMS.%20Samples%20were%20collected%20between%207%20a.m.%20and%2010%20a.m.%20Exclusion%20criteria%20were%20concomitant%20endocrine%20diseases%20and%20body%20mass%20index%20%5Cu2265%2033.%20Generalized%20additive%20model%20for%20location%2C%20scale%20and%20shape%2C%20the%20nonparametric%20or%20robust%20method%20was%20applied.%20We%20established%20the%20reference%20intervals%20of%20the%20nine%20steroid%20hormones%20by%20sex%2C%20age%2C%20and%20pubertal%20stage.%20Below%20the%20age%20of%20one%2C%20we%20observed%20the%20surge%20of%20androgen%20and%20estrogen%20which%20implied%20mini-puberty.%20At%20the%20same%20period%20of%20life%2C%20aldosterone%20and%20cortisone%20levels%20were%20very%20high%20reflecting%20physiological%20hyperaldosteronism.%20An%20increase%20of%20steroid%20hormones%20during%20the%20pubertal%20development%20and%20slow%20decrease%20towards%20senescence%20after%20the%20peak%20at%20early%20adulthood%20were%20observed.%20Due%20to%20the%20increase%20of%20CBG%20synthesis%2C%20cortisol%20levels%20were%20increased%20under%20oral%20contraceptives%20%28OC%29%20significantly%20%28p%5Cu202f%3C%5Cu202f0.0001%29%2C%20while%20OC%20suppressed%20progesterone%2C%2017-OHP%2C%20androstenedione%2C%20and%20estradiol%20%28p%5Cu202f%3C%5Cu202f0.0001%29.%20Our%20results%20will%20facilitate%20the%20interpretation%20of%20patient%20data%20in%20routine%20diagnostics%20with%20the%20use%20of%20LC-MS%5C%2FMS%20method.%20Since%20LC-MS%5C%2FMS%20methods%20have%20shown%20good%20comparability%20among%20the%20different%20laboratories%2C%20our%20reference%20intervals%20can%20be%20further%20adopted%20in%20other%20laboratories%20equipped%20with%20LC-MS%5C%2FMS%2C%20once%20the%20validation%20with%20a%20small%20number%20of%20reference%20samples%20is%20performed.%22%2C%22date%22%3A%2210%202019%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1016%5C%2Fj.jsbmb.2019.105409%22%2C%22ISSN%22%3A%221879-1220%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.jsbmb.2019.105409%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222024-01-30T09%3A08%3A14Z%22%7D%7D%2C%7B%22key%22%3A%22I9UQAA63%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Eckelt%20et%20al.%22%2C%22parsedDate%22%3A%222019%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EEckelt%2C%20Felix%2C%20Mandy%20Vogel%2C%20Mandy%20Geserick%2C%20Toralf%20Kirsten%2C%20Yoon%20Ju%20Bae%2C%20Ronny%20Baber%2C%20Michael%20Schaab%2C%20et%20al.%20%26%23x201C%3BCalcitonin%20Measurement%20in%20Pediatrics%3A%20Reference%20Ranges%20Are%20Gender-Dependent%2C%20Validation%20in%20Medullary%20Thyroid%20Cancer%20and%20Thyroid%20Diseases.%26%23x201D%3B%20%3Ci%3EClinical%20Chemistry%20and%20Laboratory%20Medicine%20%28CCLM%29%3C%5C%2Fi%3E%2057%2C%20no.%208%20%282019%29%3A%201242%26%23×2013%3B50.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1515%5C%2Fcclm-2018-1186%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1515%5C%2Fcclm-2018-1186%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Calcitonin%20Measurement%20in%20Pediatrics%3A%20Reference%20Ranges%20Are%20Gender-Dependent%2C%20Validation%20in%20Medullary%20Thyroid%20Cancer%20and%20Thyroid%20Diseases%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Felix%22%2C%22lastName%22%3A%22Eckelt%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Geserick%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Toralf%22%2C%22lastName%22%3A%22Kirsten%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Yoon%20Ju%22%2C%22lastName%22%3A%22Bae%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ronny%22%2C%22lastName%22%3A%22Baber%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Michael%22%2C%22lastName%22%3A%22Schaab%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Joachim%22%2C%22lastName%22%3A%22Thiery%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Roland%22%2C%22lastName%22%3A%22Pfaeffle%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Friedhelm%22%2C%22lastName%22%3A%22Raue%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Juergen%22%2C%22lastName%22%3A%22Kratzsch%22%7D%5D%2C%22abstractNote%22%3A%22%22%2C%22date%22%3A%2202.2019%22%2C%22language%22%3A%22%22%2C%22DOI%22%3A%2210.1515%5C%2Fcclm-2018-1186%22%2C%22ISSN%22%3A%221437-4331%22%2C%22url%22%3A%22http%3A%5C%2F%5C%2Fwww.degruyter.com%5C%2Fview%5C%2Fj%5C%2Fcclm.2019.57.issue-8%5C%2Fcclm-2018-1186%5C%2Fcclm-2018-1186.xml%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-23T12%3A36%3A25Z%22%7D%7D%2C%7B%22key%22%3A%226I7EFLG4%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Schmidt%20et%20al.%22%2C%22parsedDate%22%3A%222017-02%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3ESchmidt%2C%20Ricarda%2C%20Robert%20Richter%2C%20Anne%20Brauhardt%2C%20Andreas%20Hiemisch%2C%20Wieland%20Kiess%2C%20and%20Anja%20Hilbert.%20%26%23x201C%3BParental%20Feeding%20Practices%20in%20Families%20with%20Children%20Aged%202%26%23×2013%3B13%20Years%3A%20Psychometric%20Properties%20and%20Child%20Age-Specific%20Norms%20of%20the%20German%20Version%20of%20the%20Child%20Feeding%20Questionnaire%20%28Cfq%29.%26%23x201D%3B%20%3Ci%3EAppetite%3C%5C%2Fi%3E%20109%20%28February%202017%29%3A%20154%26%23×2013%3B64.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.appet.2016.11.038%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.appet.2016.11.038%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Parental%20Feeding%20Practices%20in%20Families%20with%20Children%20Aged%202%5Cu201313%20Years%3A%20Psychometric%20Properties%20and%20Child%20Age-Specific%20Norms%20of%20the%20German%20Version%20of%20the%20Child%20Feeding%20Questionnaire%20%28cfq%29%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ricarda%22%2C%22lastName%22%3A%22Schmidt%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Robert%22%2C%22lastName%22%3A%22Richter%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anne%22%2C%22lastName%22%3A%22Brauhardt%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andreas%22%2C%22lastName%22%3A%22Hiemisch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anja%22%2C%22lastName%22%3A%22Hilbert%22%7D%5D%2C%22abstractNote%22%3A%22The%20Child%20Feeding%20Questionnaire%20%28CFQ%29%20is%20a%20self-report%20questionnaire%20for%20assessing%20parental%20attitudes%20to%20child%20weight%20and%20parental%20feeding%20practices.%20Previous%20evaluations%20of%20its%20psychometric%20properties%20were%20conducted%20primarily%20with%20small%20to%20medium-sized%20samples%20%28N%5Cu00a0%3C%5Cu00a0500%29%20and%20a%20small%20range%20of%20children%27s%20age.%20The%20present%20study%20aims%20to%20analyze%20the%20psychometric%20properties%20of%20the%20CFQ%20in%20a%20large%20German%20community%20sample%20and%2C%20for%20the%20first%20time%2C%20to%20establish%20normative%20data.%20Within%20the%20population-based%20LIFE%20Child%20study%2C%20the%20CFQ%20was%20administered%20to%20N%5Cu00a0%3D%5Cu00a0982%20mothers%20of%202-%20to%2013-year-old%20children.%20Psychometric%20analyses%20on%20item%20statistics%20and%20internal%20consistency%20were%20conducted.%20Using%20structural%20equation%20modeling%2C%20four%20empirically-based%20factorial%20models%20of%20the%20CFQ%20were%20evaluated%2C%20and%20measurement%20invariance%20across%20child%20age%20groups%20and%20sex%20was%20examined.%20Age-specific%20norms%20for%20the%20CFQ%20subscales%20were%20computed.%20Item%20statistics%20were%20highly%20favorable%20for%20the%20majority%20of%20items%2C%20but%20floor%20and%20ceiling%20effects%20were%20found%20for%2014%20of%2031%20items.%20Internal%20consistency%20of%20the%20CFQ%20subscales%20ranged%20from%20acceptable%20to%20excellent%20%280.71%5Cu00a0%5Cu2264%5Cu00a0%5Cu03b1%5Cu00a0%5Cu2264%5Cu00a00.91%29%2C%20except%20for%20the%20subscale%20Perceived%20Responsibility%20%28%5Cu03b1%5Cu00a0%3D%5Cu00a00.65%29.%20Regarding%20factorial%20validity%2C%20an%20eight-factor%20model%20with%20the%20newly%20created%20Reward%20subscale%20provided%20the%20best%20fit%20to%20the%20data.%20This%20model%20was%20factorial%20invariant%20across%20child%20sex%20and%20adjacent%20age%20groups.%20Maternal%20and%20child%20weight%20status%20showed%20large%20effects%20on%20CFQ%20subscale%20scores.%20The%20analyses%20established%20good%20psychometric%20properties%20for%20the%20German%20version%20of%20the%20CFQ%20and%20confirmed%20an%20eight-factor%20model.%20The%20provided%20norms%20allow%20for%20the%20comparison%20of%20individual%20parental%20feeding%20practices%20and%20change%20over%20time.%20The%20CFQ%27s%20sensitivity%20to%20change%20and%20longitudinal%20associations%20of%20parental%20feeding%20practices%20and%20child%20weight%20status%20warrant%20further%20research.%22%2C%22date%22%3A%22February%2C%202017%22%2C%22language%22%3A%22%22%2C%22DOI%22%3A%2210.1016%5C%2Fj.appet.2016.11.038%22%2C%22ISSN%22%3A%220195-6663%22%2C%22url%22%3A%22http%3A%5C%2F%5C%2Fwww.sciencedirect.com%5C%2Fscience%5C%2Farticle%5C%2Fpii%5C%2FS0195666316308583%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-24T11%3A25%3A41Z%22%7D%7D%2C%7B%22key%22%3A%22Y9DRG7FA%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Bussler%20et%20al.%22%2C%22parsedDate%22%3A%222017%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EBussler%2C%20Sarah%2C%20Mandy%20Vogel%2C%20Diana%20Pietzner%2C%20Kristian%20Harms%2C%20Theresa%20Buzek%2C%20Melanie%20Penke%2C%20Norman%20H%26%23xE4%3Bndel%2C%20et%20al.%20%26%23x201C%3BNew%20Pediatric%20Percentiles%20of%20Liver%20Enzyme%20Serum%20Levels%20%28Alt%2C%20Ast%2C%20Ggt%29%3A%20Effects%20of%20Age%2C%20Sex%2C%20Bmi%20and%20Pubertal%20Stage.%26%23x201D%3B%20%3Ci%3EHepatology%3C%5C%2Fi%3E%2C%202017%2C%20n%5C%2Fa-n%5C%2Fa.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1002%5C%2Fhep.29542%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1002%5C%2Fhep.29542%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22New%20Pediatric%20Percentiles%20of%20Liver%20Enzyme%20Serum%20Levels%20%28alt%2C%20Ast%2C%20Ggt%29%3A%20Effects%20of%20Age%2C%20Sex%2C%20Bmi%20and%20Pubertal%20Stage%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Sarah%22%2C%22lastName%22%3A%22Bussler%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Diana%22%2C%22lastName%22%3A%22Pietzner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Kristian%22%2C%22lastName%22%3A%22Harms%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Theresa%22%2C%22lastName%22%3A%22Buzek%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Melanie%22%2C%22lastName%22%3A%22Penke%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Norman%22%2C%22lastName%22%3A%22H%5Cu00e4ndel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ulrich%22%2C%22lastName%22%3A%22Baumann%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Gunter%22%2C%22lastName%22%3A%22Flemming%22%7D%5D%2C%22abstractNote%22%3A%22The%20present%20study%20aims%20to%20clarify%20the%20effects%20of%20sex%2C%20age%2C%20BMI%20and%20puberty%20on%20transaminase%20serum%20levels%20in%20children%20and%20adolescents%20and%20to%20provide%20new%20age-%20and%20sex-related%20percentiles%20for%20alanine%20aminotransferase%20%28ALT%29%2C%20aspartate%20aminotransferase%20%28AST%29%20and%20%5Cu03b3-glutamyltransferase%20%28GGT%29.%20Venous%20blood%20and%20anthropometric%20data%20were%20collected%20from%204%2C126%20cases.%20Excluded%20were%20cases%20of%20participants%20with%20potential%20hepatotoxic%20medication%2C%20with%20evidence%20of%20potential%20illness%20at%20the%20time%20of%20blood%20sampling%20and%20non-normal%20BMI%20%28BMI%5Cu2009%3C%5Cu200910th%20or%5Cu2009%3E%5Cu200990th%29.%20The%20resulting%20data%20%28N%20%3D%203%2C131%20cases%29%20were%20used%20for%20the%20calculations%20of%20ALT%2C%20AST%2C%20and%20GGT%20percentiles.%20Age-%20and%20sex-related%20reference%20intervals%20were%20established%20by%20using%20an%20LMSP-type%20method.%20Serum%20levels%20of%20transaminases%20follow%20age-specific%20patterns%20and%20relate%20to%20the%20onset%20of%20puberty.%20This%20observation%20is%20more%20pronounced%20in%20girls%20than%20in%20boys.%20The%20ALT%20percentiles%20showed%20similar%20shaped%20patterns%20in%20both%20sexes.%20Multivariate%20regression%20confirmed%20significant%20effects%20of%20puberty%20and%20BMI-SDS%20%28%5Cu03b2%20%3D%202.21%29%20on%20ALT.%20Surprisingly%2C%20AST%20serum%20levels%20were%20negatively%20influenced%20by%20age%20%28%5Cu03b2%20%3D%20-1.42%29%20and%20BMI-SDS%20%28%5Cu03b2%20%3D%20-0.15%29.%20The%20GGT%20percentiles%20revealed%20significant%20sex-specific%20differences%2C%20correlated%20positively%20with%20age%20%28%5Cu03b2%20%3D%200.37%29%20and%20showed%20significant%20association%20with%20BMI-SDS%20%28%5Cu03b2%20%3D%201.16%29.%20Conclusion%3A%20Current%20reference%20values%20of%20ALT%2C%20AST%20and%20GGT%20serum%20levels%20were%20calculated%20for%20children%20between%2011%20months%20and%2016.0%20years%2C%20using%20modern%20analytical%20and%20statistical%20methods.%20This%20study%20extends%20the%20current%20knowledge%20about%20transaminases%20by%20revealing%20influences%20of%20age%2C%20sex%2C%20BMI%2C%20and%20puberty%20on%20the%20serum%20concentrations%20of%20all%20three%20parameters%20and%20has%20for%20these%20parameters%20one%20of%20the%20largest%20sample%20sizes%20published%20so%20far.%20This%20article%20is%20protected%20by%20copyright.%20All%20rights%20reserved.%22%2C%22date%22%3A%222017%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1002%5C%2Fhep.29542%22%2C%22ISSN%22%3A%221527-3350%22%2C%22url%22%3A%22http%3A%5C%2F%5C%2Fonlinelibrary.wiley.com%5C%2Fdoi%5C%2F10.1002%5C%2Fhep.29542%5C%2Fabstract%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-07T07%3A01%3A52Z%22%7D%7D%2C%7B%22key%22%3A%22Q298TYNA%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Vogel%20et%20al.%22%2C%22parsedDate%22%3A%222017%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EVogel%2C%20Mandy%2C%20Toralf%20Kirsten%2C%20J%26%23xFC%3Brgen%20Kratzsch%2C%20Christoph%20Engel%2C%20and%20Wieland%20Kiess.%20%26%23x201C%3BA%20Combined%20Approach%20to%20Generate%20Laboratory%20Reference%20Intervals%20Using%20Unbalanced%20Longitudinal%20Data.%26%23x201D%3B%20%3Ci%3EJournal%20of%20Pediatric%20Endocrinology%20and%20Metabolism%3C%5C%2Fi%3E%2030%2C%20no.%207%20%282017%29%3A%20767%26%23×2013%3B73.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1515%5C%2Fjpem-2017-0171%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1515%5C%2Fjpem-2017-0171%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22A%20Combined%20Approach%20to%20Generate%20Laboratory%20Reference%20Intervals%20Using%20Unbalanced%20Longitudinal%20Data%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Toralf%22%2C%22lastName%22%3A%22Kirsten%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J%5Cu00fcrgen%22%2C%22lastName%22%3A%22Kratzsch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christoph%22%2C%22lastName%22%3A%22Engel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%5D%2C%22abstractNote%22%3A%22Background%3A%5CnThe%20interpretation%20of%20individual%20laboratory%20test%20results%20requires%20the%20availability%20of%20population-based%20reference%20intervals.%20In%20children%2C%20reference%20interval%20estimation%20has%20to%20consider%20frequently%20the%20strong%20age-dependency.%20Generally%2C%20for%20the%20construction%20of%20reference%20intervals%2C%20a%20sufficiently%20large%20number%20of%20independent%20measurement%20values%20is%20required.%20Data%20selections%20from%20hospitals%20or%20cohort%20studies%20often%20comprise%20dependencies%20violating%20the%20independence%20assumption.%5CnMethods%3A%5CnIn%20this%20article%2C%20we%20propose%20a%20combination%20of%20LMS-like%20%28mean%2C%20M%3B%20coefficient%20of%20variation%2C%20S%3B%20skewness%2C%20%5Cu03bb%20or%20L%29%20and%20resampling%20methods%20to%20overcome%20this%20drawback.%20The%20former%20is%20recommended%20by%20the%20World%20Health%20Organization%20%28WHO%29%20for%20the%20construction%20of%20continuous%20reference%20intervals%20of%20anthropometric%20measurements%20in%20children.%20The%20approach%20allows%20the%20inclusion%20of%20dependent%20measurements%2C%20for%20example%2C%20repeated%20measurements%20per%20subject.%20It%20also%20provides%20pointwise%20confidence%20envelopes%20as%20a%20measure%20of%20reliability.%5CnResults%20and%20conclusions%3A%5CnThe%20combination%20of%20LMS-type%20methods%20and%20resampling%20provides%20a%20feasible%20approach%20to%20estimate%20age-dependent%20percentiles%20and%20reference%20intervals%20using%20unbalanced%20longitudinal%20data.%22%2C%22date%22%3A%222017%22%2C%22language%22%3A%22%22%2C%22DOI%22%3A%2210.1515%5C%2Fjpem-2017-0171%22%2C%22ISSN%22%3A%22%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-24T13%3A36%3A25Z%22%7D%7D%2C%7B%22key%22%3A%224ZVINPSM%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Dathan-Stumpf%20et%20al.%22%2C%22parsedDate%22%3A%222016-07%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EDathan-Stumpf%2C%20Anne%2C%20Mandy%20Vogel%2C%20Andreas%20Hiemisch%2C%20Joachim%20Thiery%2C%20Ralph%20Burkhardt%2C%20J%26%23xFC%3Brgen%20Kratzsch%2C%20and%20Wieland%20Kiess.%20%26%23x201C%3BPediatric%20Reference%20Data%20of%20Serum%20Lipids%20and%20Prevalence%20of%20Dyslipidemia%3A%20Results%20from%20a%20Population-Based%20Cohort%20in%20Germany.%26%23x201D%3B%20%3Ci%3EClinical%20Biochemistry%3C%5C%2Fi%3E%2049%2C%20no.%2010%26%23×2013%3B11%20%28July%202016%29%3A%20740%26%23×2013%3B49.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.clinbiochem.2016.02.010%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.clinbiochem.2016.02.010%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Pediatric%20Reference%20Data%20of%20Serum%20Lipids%20and%20Prevalence%20of%20Dyslipidemia%3A%20Results%20from%20a%20Population-Based%20Cohort%20in%20Germany%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anne%22%2C%22lastName%22%3A%22Dathan-Stumpf%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andreas%22%2C%22lastName%22%3A%22Hiemisch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Joachim%22%2C%22lastName%22%3A%22Thiery%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ralph%22%2C%22lastName%22%3A%22Burkhardt%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J%5Cu00fcrgen%22%2C%22lastName%22%3A%22Kratzsch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%5D%2C%22abstractNote%22%3A%22Background%3A%5CnSerum%20lipid%20concentrations%20are%20thought%20to%20be%20risk%20factors%20for%20the%20development%20of%20cardiovascular%20disease.%20The%20present%20study%20aims%20to%20investigate%20the%20prevalence%20of%20dyslipidemia%20and%20provide%20sex-%20and%20age-related%20reference%20values%20for%20triglycerides%2C%20total%20cholesterol%2C%20LDL%20and%20HDL%20cholesterol%20as%20well%20as%20apolipoproteins%20A1%20and%20B%20by%20using%20modern%20analytical%20approaches.%5CnMaterials%20and%20methods%3A%5CnVenous%20blood%20and%20anthropometric%20data%20were%20collected%20from%202571%20subjects%20of%20the%20LIFE%20Child%20study%2C%20aged%20between%200.5%20and%2016%20years.%20Age-%20and%20gender-related%20reference%20intervals%20%283rd%20and%2097th%20percentiles%29%20were%20established%20by%20using%20Cole%27s%20LMS%20method.%5CnResults%3A%5CnSerum%20concentrations%20of%20TC%2C%20LDL-C%2C%20TG%20and%20ApoB%20were%20higher%20in%20girls%20than%20in%20boys.%20In%20girls%20TC%20reached%20peak%20levels%20two%20years%20earlier%20than%20in%20boys.%20Triglyceride%20levels%20initially%20declined%20until%20the%20school%20age.%20Until%20early%20adolescence%20there%20was%20a%20steady%20increase.%20The%20LDL-C%20concentrations%20in%20girls%20and%20boys%20followed%20similar%20patterns%20to%20that%20of%20TC.%20Up%20to%20the%20age%20of%208%20years%2C%20a%20continuous%20increase%20in%20HDL%20levels%20for%20both%20sexes%20was%20found.%20Due%20to%20the%20strong%20correlation%20between%20HDL-C%20and%20ApoA1%20%28r%20%3D%200.87%29%20or%20rather%20between%20LDL-C%20and%20ApoB%20%28r%20%3D%200.93%29%2C%20the%20respective%20percentiles%20showed%20very%20similar%20patterns.%20Dyslipidemia%20prevalence%20were%20as%20follows%3A%20increased%20TC%207.8%25%2C%20increased%20LDL%206.1%25%2C%20increased%20TG%200%5Cu20139%20years%2022.1%25%2C%20increased%20TG%2010%5Cu201316%20years%2011.7%25%2C%20and%20decreased%20HDL%208.0%25.%5CnConclusion%3A%5CnAge-%20and%20sex-related%20trends%20for%20all%20parameters%20are%20similar%20to%20those%20of%20the%20German%20KIGGS%20study.%20With%20the%20exception%20of%20HDL%20cholesterol%2C%20the%20prevalence%20of%20dyslipidemias%20in%20the%20German%20LIFE%20Child%20cohort%20are%20similar%20to%20the%20US-American%20prevalence.%22%2C%22date%22%3A%22July%202016%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1016%5C%2Fj.clinbiochem.2016.02.010%22%2C%22ISSN%22%3A%2200099120%22%2C%22url%22%3A%22http%3A%5C%2F%5C%2Flinkinghub.elsevier.com%5C%2Fretrieve%5C%2Fpii%5C%2FS000991201600076X%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-23T12%3A22%3A17Z%22%7D%7D%2C%7B%22key%22%3A%22CZATTM23%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Rieger%20et%20al.%22%2C%22parsedDate%22%3A%222016-05%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3ERieger%2C%20Kristin%2C%20Mandy%20Vogel%2C%20Christoph%20Engel%2C%20Uta%20Ceglarek%2C%20Joachim%20Thiery%2C%20J%26%23xFC%3Brgen%20Kratzsch%2C%20Kristian%20Harms%2C%20Fabian%20Glock%2C%20Andreas%20Hiemisch%2C%20and%20Wieland%20Kiess.%20%26%23x201C%3BReference%20Intervals%20for%20Iron-Related%20Blood%20Parameters%3A%20Results%20from%20a%20Population-Based%20Cohort%20Study%20%28Life%20Child%29.%26%23x201D%3B%20%3Ci%3ELaboratoriumsMedizin%3C%5C%2Fi%3E%2040%2C%20no.%20s1%20%28May%202016%29%3A%2031%26%23×2013%3B41.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1515%5C%2Flabmed-2016-0019%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1515%5C%2Flabmed-2016-0019%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Reference%20Intervals%20for%20Iron-Related%20Blood%20Parameters%3A%20Results%20from%20a%20Population-Based%20Cohort%20Study%20%28life%20Child%29%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Kristin%22%2C%22lastName%22%3A%22Rieger%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christoph%22%2C%22lastName%22%3A%22Engel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Uta%22%2C%22lastName%22%3A%22Ceglarek%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Joachim%22%2C%22lastName%22%3A%22Thiery%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J%5Cu00fcrgen%22%2C%22lastName%22%3A%22Kratzsch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Kristian%22%2C%22lastName%22%3A%22Harms%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Fabian%22%2C%22lastName%22%3A%22Glock%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andreas%22%2C%22lastName%22%3A%22Hiemisch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%5D%2C%22abstractNote%22%3A%22Background%3A%20Pediatric%20reference%20intervals%20for%20iron-related%20parameters%20are%20determined%20continuously%20over%20time%20from%20a%20highly%20standardized%20sample%20collection%20by%20application%20of%20the%20R-package%20generalized%20additive%20models%20for%20location%2C%20scale%20and%20shape%20%28GAMLSS%29%2C%20which%20is%20little%20known%20in%20laboratory%20medicine.%5CnMethods%3A%20Two%20thousand%20seven%20hundred%20and%20seventy-eight%20samples%20from%20Leipzig%20research%20center%20for%20civilization%20diseases%20%28LIFE%29%20Child%20participants%20at%20the%20age%20of%202.5%5Cu201319%20years%20were%20analyzed%20on%20a%20Sysmex%20XN-9000%20for%20hemoglobin%20and%20reticulocytes%20and%20on%20a%20Roche%20Cobas%208000%20for%20transferrin%20and%20ferritin.%20Reference%20intervals%20were%20established%20by%20repeated%20model%20calculation%20by%20use%20of%20the%20LMS%20%28%5Cu03bb-%5Cu00b5-%5Cu03c3%29%20method%20from%20Cole%20with%20specifically%20weighted%20subsamples.%5CnResults%3A%20Continuous%20and%20gender-specific%20reference%20intervals%20as%20well%20as%20smoothed%20percentile%20curves%20were%20established%20for%20hemoglobin%2C%20ferritin%2C%20reticulocytes%20and%20transferrin.%20In%20the%20case%20of%20repeated%20model%20calculations%2C%20single%20curves%20and%20averaged%20percentile%20curves%20were%20shown.%20The%20single%20curves%20outlined%20potential%20variations%20of%20the%20different%20parameter%20trends.%20The%20averaged%20percentile%20curves%20submitted%20a%20stable%20assessment%20of%20curve%20trends%20over%20time%20for%20iron-related%20parameters%20in%20childhood%20and%20adolescence.%5CnConclusions%3A%20For%20the%20first%20time%20current%20age-%20and%20gender-%20specific%20reference%20intervals%20are%20available%20by%20application%20of%20the%20R-package%20GAMLSS%20and%20the%20laboratory%20techniques%20applied%20here.%20Compared%20to%20earlier%20studies%2C%20previous%20findings%20can%20be%20completed%20and%20discrepancies%20related%20to%20different%20methodical%20approaches%2C%20can%20be%20pointed%20out.%20Relevant%20findings%20for%20the%20diagnosis%20of%20iron%20deficiency%20anemia%2C%20such%20as%20gender-dependent%20assessment%20of%20hemoglobin%20starting%20at%20the%20age%20of%2011%20instead%20of%2015%20%5Baccording%20to%20the%20World%20Health%20Organization%20%28WHO%29%5D%2C%20are%20presented.%22%2C%22date%22%3A%222016-05%22%2C%22language%22%3A%22%22%2C%22DOI%22%3A%2210.1515%5C%2Flabmed-2016-0019%22%2C%22ISSN%22%3A%220342-3026%22%2C%22url%22%3A%22http%3A%5C%2F%5C%2Fdx.doi.org%5C%2F10.1515%5C%2Flabmed-2016-0019%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222024-04-29T08%3A55%3A15Z%22%7D%7D%5D%7D
Grosse-Thie, Charlotte, Mandy Vogel, Ronny Baber, Uta Ceglarek, and Wieland Kiess. “Bilirubin Levels in Infancy and Their Associations with Body Weight, Levels of Iron-Related Parameters and Steroid Hormone Levels.” Metabolites 14, no. 7 (July 19, 2024): 393. https://doi.org/10.3390/metabo14070393.
Prenzel, Freerk, Thorsten Kaiser, Anja Willenberg, Maike vom Hove, Gunter Flemming, Lars Fischer, Jürgen Kratzsch, Wieland Kiess, and Mandy Vogel. “Reference Intervals and Percentiles for Soluble Transferrin Receptor and STfR/Log Ferritin Index in Healthy Children and Adolescents.” Clinical Chemistry and Laboratory Medicine (CCLM), July 8, 2024. https://doi.org/10.1515/cclm-2024-0369.
Fechner, Anna, Anja Willenberg, Niels Ziegelasch, Andreas Merkenschlager, Wieland Kiess, and Mandy Vogel. “Creatine Kinase Serum Levels in Children Revisited: New Reference Intervals from a Large Cohort of Healthy Children and Adolescents.” Clinica Chimica Acta 560 (June 15, 2024): 119726. https://doi.org/10.1016/j.cca.2024.119726.
Ravi Teja, Kasagani Venkata, Bhanu Malhotra, Mandy Vogel, Raman Kumar Marwaha, Arun Aggarwal, Rimesh Pal, Liza Das, et al. “Normative Data for Insulin-like Growth Factor-1 (IGF-1) in Healthy Children and Adolescents from India.” The Journal of Clinical Endocrinology and Metabolism, May 15, 2024, dgae340. https://doi.org/2024061217375967200.
Wilpert, Nina-Maria, Roma Thamm, Michael Thamm, Jürgen Kratzsch, Dominik Seelow, Mandy Vogel, Heiko Krude, and Markus Schuelke. “Normal Values for the FT3/FT4 Ratio: Centile Charts (0–29 Years) and Their Application for the Differential Diagnosis of Children with Developmental Delay.” International Journal of Molecular Sciences 25, no. 16 (January 2024): 8585. https://doi.org/10.3390/ijms25168585.
Ridefelt, Peter, Johan Saldeen, Mandy Vogel, Uta Ceglarek, Wieland Kiess, and Anders Larsson. “Pediatric Reference Intervals for Serum Folate and Cobalamin Based on a European Population without Exposure to Folic Acid Fortification.” Scandinavian Journal of Clinical and Laboratory Investigation online ahead of print, no. 0 (2024): 1–5. https://doi.org/10.1080/00365513.2024.2330918.
Strauch, Jacqueline-Michéle, Mandy Vogel, Christof Meigen, Uta Ceglarek, Jürgen Kratzsch, Anja Willenberg, and Wieland Kiess. “Pediatric Reference Values of Alkaline Phosphatase: Analysis from a German Population-Based Cohort and Influence of Anthropometric and Blood Parameters.” Bone 174 (September 1, 2023): 116809. https://doi.org/10.1016/j.bone.2023.116809.
Maidowski, Ludwig, Wieland Kiess, Ronny Baber, Anne Dathan-Stumpf, Uta Ceglarek, and Mandy Vogel. “Tracking of Serum Lipids in Healthy Children on a Year-to-Year Basis.” BMC Cardiovascular Disorders 23, no. 1 (August 2, 2023): 386. https://doi.org/10.1186/s12872-023-03391-9.
Stürzebecher, P., M. Schlingmann, K. Uttinger, M. Vogel, U. Ceglarek, B. Isermann, W. Kiess, A. Körner, and U. Laufs. “Lipoprotein(A) Serum Concentrations in Children Are Independent of Age, Sex, or Body Mass Index.” In Atherosclerosis, 379:S20. Elsevier, 2023. https://doi.org/10.1016/j.atherosclerosis.2023.06.739.
Söhnel, Tanja, Christof Meigen, Andreas Hiemisch, Siegfried Wahl, Focke Ziemssen, Carolin Truckenbrod, Katharina Hübner, and Wieland Kiess. “Normative Data for Macular and Retinal Nerve Fibre Layer Thickness in Healthy German Children and Adolescents Using Optical Coherence Tomography.” Ophthalmic and Physiological Optics, March 17, 2023, opo.13123. https://doi.org/10.1111/opo.13123.
Brunnert, Lina, Ika Damayanti Puasa, Antje Garten, Melanie Penke, Susanne Gaul, Nico Grafe, Thomas Karlas, Wieland Kiess, Gunter Flemming, and Mandy Vogel. “Pediatric Percentiles for Transient Elastography Measurements – Effects of Age, Sex, Weight Status and Pubertal Stage.” Frontiers in Endocrinology 13 (September 27, 2022): 1030809. https://doi.org/10.3389/fendo.2022.1030809.
Hörenz, Charlott, Mandy Vogel, Kerstin Wirkner, Uta Ceglarek, Joachim Thiery, Roland Pfäffle, Wieland Kiess, and Jürgen Kratzsch. “BMI and Contraceptives Affect New Age-, Sex-, and Puberty-Adjusted IGF-I and IGFBP-3 Reference Ranges Across Life Span.” The Journal of Clinical Endocrinology & Metabolism, March 16, 2022, dgac157. https://doi.org/10.1210/clinem/dgac157.
Kiess, Alexandra, Jessica Green, Anja Willenberg, Uta Ceglarek, Ingo Dähnert, Anne Jurkutat, Antje Körner, Andreas Hiemisch, Wieland Kiess, and Mandy Vogel. “Age-Dependent Reference Values for Hs-Troponin T and Nt-Probnp and Determining Factors in a Cohort of Healthy Children (the Life Child Study).” Pediatric Cardiology 43 (March 12, 2022): 1071–83. https://doi.org/10.1007/s00246-022-02827-x.
Hovestadt, Ina, Wieland Kiess, Christiane Lewien, Anja Willenberg, Tanja Poulain, Christof Meigen, Antje Körner, and Mandy Vogel. “HbA1c Percentiles and the Association between BMI, Age, Gender, Puberty and HbA1c Levels in Healthy German Children and Adolescents.” Pediatric Diabetes 23, no. 2 (March 2022): 194–202. https://doi.org/10.1111/pedi.13297.
Wessela, Sven, Christof Meigen, Tanja Poulain, Carolin Sobek, Mandy Vogel, Siegfried Möller, and Wieland Kiess. “Reference Centiles Based on Year-to-Year Changes for a Longitudinal Evaluation of Motor Performance in Children and Adolescents.” PloS One 17, no. 1 (January 2022): e0262163. https://doi.org/10.1371/journal.pone.0262163.
Dienerowitz, Tobias, Thomas Peschel, Mandy Vogel, Tanja Poulain, Christoph Engel, Wieland Kiess, Michael Fuchs, and Thomas Berger. “Establishing Normative Data on Singing Voice Parameters of Children and Adolescents with Average Singing Activity Using the Voice Range Profile.” Folia Phoniatrica et Logopaedica: Official Organ of the International Association of Logopedics and Phoniatrics (IALP) 73, no. 6 (December 2021). https://doi.org/10.1159/000513521.
Kratzsch, Juergen, Mandy Vogel, Tanja Poulain, and Wieland Kiess. “New Reference Intervals for Endocrinological Biomarkers in Pediatric Patients: What Can We Learn from the Life Child Study?” LaboratoriumsMedizin 45, no. 6 (November 2021). https://doi.org/10.1515/labmed-2021-0145.
Eckelt, Felix, Roland Pfaeffle, Wieland Kiess, and Juergen Kratzsch. “Calcitonin and Complementary Biomarkers in the Diagnosis of Hereditary Medullary Thyroid Carcinoma in Children and Adolescents.” Journal of Pediatric Endocrinology & Metabolism: JPEM online ahead of print (September 2021). https://doi.org/10.1515/jpem-2021-0163.
Surup, Hans, Mandy Vogel, Antje Koerner, Andreas Hiemisch, Lea Oelkers, Anja Willenberg, Wieland Kiess, and Juergen Kratzsch. “Pediatric Reference Intervals for Thyrotropin, Free Triiodothyronine, and Free Thyroxine and the Relevance of Body Mass Index and Puberty in Measurement Interpretation.” Thyroid: Official Journal of the American Thyroid Association 31, no. 8 (August 2021): 1192–1202. https://doi.org/10.1089/thy.2020.0780.
Kempf, Elena, Mandy Vogel, Tim Vogel, Jürgen Kratzsch, Kathrin Landgraf, Andreas Kühnapfel, Ruth Gausche, et al. “Dynamic Alterations in Linear Growth and Endocrine Parameters in Children with Obesity and Height Reference Values.” EClinicalMedicine 37 (June 2021): 100977. https://doi.org/10.1016/j.eclinm.2021.100977.
Truckenbrod, Carolin, Christof Meigen, Manuela Brandt, Mandy Vogel, Pablo Sanz Diez, Siegfried Wahl, Anne Jurkutat, and Wieland Kiess. “Longitudinal Analysis of Axial Length Growth in a German Cohort of Healthy Children and Adolescents.” Ophthalmic & Physiological Optics: The Journal of the British College of Ophthalmic Opticians (Optometrists) 41, no. 3 (May 2021): 532–40. https://doi.org/10.1111/opo.12817.
Kreusler, Paulina, Mandy Vogel, Anja Willenberg, Ronny Baber, Yvonne Dietz, Antje Körner, Uta Ceglarek, and Wieland Kiess. “Folate and Cobalamin Serum Levels in Healthy Children and Adolescents and Their Association with Age, Sex, Bmi and Socioeconomic Status.” Nutrients 13, no. 2 (February 2021). https://doi.org/10.3390/nu13020546.
Wallborn, Tillmann, Mandy Vogel, Antje Kneuer, Michael Thamm, Katalin Dittrich, Wieland Kiess, and Jürgen Kratzsch. “Spot Urine Iodine Levels Below the Who Recommendation Are Not Related to Impaired Thyroid Function in Healthy Children and Adolescents.” European Journal of Nutrition 60 (May 2020): 493–502. https://doi.org/10.1007/s00394-020-02268-3.
Truckenbrod, Carolin, Christof Meigen, Manuela Brandt, Mandy Vogel, Siegfried Wahl, Anne Jurkutat, and Wieland Kiess. “Reference Curves for Refraction in a German Cohort of Healthy Children and Adolescents.” PLOS ONE 15, no. 3 (March 2020): e0230291. https://doi.org/10.1371/journal.pone.0230291.
Geserick, M., M. Vogel, F. Eckelt, M. Schlingmann, A. Hiemisch, R. Baber, J. Thiery, A. Körner, W. Kiess, and J. Kratzsch. “Children and Adolescents with Obesity Have Reduced Serum Bone Turnover Markers and 25-Hydroxyvitamin D but Increased Parathyroid Hormone Concentrations – Results Derived from New Pediatric Reference Ranges.” Bone 132 (2020): 115124. https://doi.org/10.1016/j.bone.2019.115124.
Dathan-Stumpf, Anne, Mandy Vogel, Alexander Jank, Joachim Thiery, Wieland Kiess, and Holger Stepan. “Reference Intervals of Serum Lipids in the Second and Third Trimesters of Pregnancy in a Caucasian Cohort: The Life Child Study.” Archives of Gynecology and Obstetrics 300, no. 6 (December 2019): 1531–39. https://doi.org/10.1007/s00404-019-05342-2.
Berger, Thomas, Thomas Peschel, Mandy Vogel, Diana Pietzner, Tanja Poulain, Anne Jurkutat, Sylvia Meuret, Christoph Engel, Wieland Kiess, and Michael Fuchs. “Speaking Voice in Children and Adolescents: Normative Data and Associations with Bmi, Tanner Stage, and Singing Activity.” Journal of Voice 33, no. 4 (July 2019): 580.e21-580.e30. https://doi.org/10.1016/j.jvoice.2018.01.006.
Kratzsch, J., R. Kolm, A. Hoppe, P. Dilba, A. Körner, K. Wirkner, A. Hiemisch, and W. Kiess. “Reference Ranges for the Elecsys® IGF-1 and IGFBP-3 Immunoassays: Effects of Age, Gender and Pubertal Stage.” Clinica Chimica Acta 493 (June 2019): S319. https://doi.org/10.1016/j.cca.2019.03.694.
Rönnecke, Elisa, Mandy Vogel, Sarah Bussler, Nico Grafe, Anne Jurkutat, Maike Schlingmann, Antje Koerner, and Wieland Kiess. “Age- and Sex-Related Percentiles of Skinfold Thickness, Waist and Hip Circumference, Waist-to-Hip Ratio and Waist-to-Height Ratio: Results from a Population-Based Pediatric Cohort in Germany (LIFE Child).” Obesity Facts 12, no. 1 (March 2019): 25–39. https://doi.org/10.1159/000494767.
Ziegelasch, Niels, Mandy Vogel, Eva Müller, Nadin Tremel, Anne Jurkutat, Markus Löffler, Nicolas Terliesner, et al. “Cystatin C Serum Levels in Healthy Children Are Related to Age, Gender, and Pubertal Stage.” Pediatric Nephrology 34, no. 3 (March 2019): 449–57. https://doi.org/10.1007/s00467-018-4087-z.
Bae, Yoon Ju, Robert Zeidler, Ronny Baber, Mandy Vogel, Kerstin Wirkner, Markus Loeffler, Uta Ceglarek, et al. “Reference Intervals of Nine Steroid Hormones Over the Life-Span Analyzed by Lc-Ms/Ms: Effect of Age, Gender, Puberty, and Oral Contraceptives.” The Journal of Steroid Biochemistry and Molecular Biology 193 (2019): 105409. https://doi.org/10.1016/j.jsbmb.2019.105409.
Eckelt, Felix, Mandy Vogel, Mandy Geserick, Toralf Kirsten, Yoon Ju Bae, Ronny Baber, Michael Schaab, et al. “Calcitonin Measurement in Pediatrics: Reference Ranges Are Gender-Dependent, Validation in Medullary Thyroid Cancer and Thyroid Diseases.” Clinical Chemistry and Laboratory Medicine (CCLM) 57, no. 8 (2019): 1242–50. https://doi.org/10.1515/cclm-2018-1186.
Schmidt, Ricarda, Robert Richter, Anne Brauhardt, Andreas Hiemisch, Wieland Kiess, and Anja Hilbert. “Parental Feeding Practices in Families with Children Aged 2–13 Years: Psychometric Properties and Child Age-Specific Norms of the German Version of the Child Feeding Questionnaire (Cfq).” Appetite 109 (February 2017): 154–64. https://doi.org/10.1016/j.appet.2016.11.038.
Bussler, Sarah, Mandy Vogel, Diana Pietzner, Kristian Harms, Theresa Buzek, Melanie Penke, Norman Händel, et al. “New Pediatric Percentiles of Liver Enzyme Serum Levels (Alt, Ast, Ggt): Effects of Age, Sex, Bmi and Pubertal Stage.” Hepatology, 2017, n/a-n/a. https://doi.org/10.1002/hep.29542.
Vogel, Mandy, Toralf Kirsten, Jürgen Kratzsch, Christoph Engel, and Wieland Kiess. “A Combined Approach to Generate Laboratory Reference Intervals Using Unbalanced Longitudinal Data.” Journal of Pediatric Endocrinology and Metabolism 30, no. 7 (2017): 767–73. https://doi.org/10.1515/jpem-2017-0171.
Dathan-Stumpf, Anne, Mandy Vogel, Andreas Hiemisch, Joachim Thiery, Ralph Burkhardt, Jürgen Kratzsch, and Wieland Kiess. “Pediatric Reference Data of Serum Lipids and Prevalence of Dyslipidemia: Results from a Population-Based Cohort in Germany.” Clinical Biochemistry 49, no. 10–11 (July 2016): 740–49. https://doi.org/10.1016/j.clinbiochem.2016.02.010.
Rieger, Kristin, Mandy Vogel, Christoph Engel, Uta Ceglarek, Joachim Thiery, Jürgen Kratzsch, Kristian Harms, Fabian Glock, Andreas Hiemisch, and Wieland Kiess. “Reference Intervals for Iron-Related Blood Parameters: Results from a Population-Based Cohort Study (Life Child).” LaboratoriumsMedizin 40, no. s1 (May 2016): 31–41. https://doi.org/10.1515/labmed-2016-0019.
2390247
T52N9QLZ
food
1
chicago-fullnote-bibliography
50
date
desc
1
1
6748
https://home.uni-leipzig.de/lifechild/wp-content/plugins/zotpress/
%7B%22status%22%3A%22success%22%2C%22updateneeded%22%3Afalse%2C%22instance%22%3Afalse%2C%22meta%22%3A%7B%22request_last%22%3A0%2C%22request_next%22%3A0%2C%22used_cache%22%3Atrue%7D%2C%22data%22%3A%5B%7B%22key%22%3A%22BRTAYN7Z%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Ober%20et%20al.%22%2C%22parsedDate%22%3A%222024-06-19%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EOber%2C%20Peggy%2C%20Tanja%20Poulain%2C%20Christof%20Meigen%2C%20Ulrike%20Spielau%2C%20Carolin%20Sobek%2C%20Wieland%20Kiess%2C%20Ulrike%20Igel%2C%20Tobias%20Lipek%2C%20and%20Mandy%20Vogel.%20%26%23x201C%3BModifiable%20Factors%20Influencing%20Attention%20Performance%20in%20Healthy%20Children%3A%20Insights%20from%20a%20Comprehensive%20School%20Nutrition%20Study.%26%23x201D%3B%20%3Ci%3EBMC%20Public%20Health%3C%5C%2Fi%3E%2024%2C%20no.%201%20%28June%2019%2C%202024%29%3A%201629.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs12889-024-19059-8%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs12889-024-19059-8%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Modifiable%20factors%20influencing%20attention%20performance%20in%20healthy%20children%3A%20insights%20from%20a%20comprehensive%20school%20nutrition%20study%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Peggy%22%2C%22lastName%22%3A%22Ober%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christof%22%2C%22lastName%22%3A%22Meigen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ulrike%22%2C%22lastName%22%3A%22Spielau%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Carolin%22%2C%22lastName%22%3A%22Sobek%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ulrike%22%2C%22lastName%22%3A%22Igel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tobias%22%2C%22lastName%22%3A%22Lipek%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%5D%2C%22abstractNote%22%3A%22BACKGROUND%3A%20There%20is%20inconclusive%20evidence%20for%20the%20effects%20of%20various%20leisure%20activities%20on%20attention%20performance%20in%20children.%20The%20literature%20reports%20inconsistent%20associations%20between%20activities%20such%20as%20physical%20activities%20or%20media%20use.%20To%20date%2C%20no%20study%20has%20thoroughly%20examined%20the%20various%20factors%20influencing%20attentional%20performance%20in%20a%20larger%20cohort%20of%20healthy%20children.%20This%20study%20aims%20to%20close%20this%20research%20gap.%5CnMETHODS%3A%20From%202018%20to%202019%2C%20the%20Leipzig%20School%20Nutrition%20Study%20collected%20data%20from%201215%20children%20and%20their%20families.%20The%20children%20report%20their%20dietary%20behavior%20%28using%20CoCu-%20Questionnaire%29%2C%20especially%20their%20participation%20in%20school%20lunch%20and%20their%20breakfast%20habits%2C%20through%20a%20paper%20questionnaire.%20Furthermore%2C%20attention%20performance%20was%20assessed%20using%20a%20validated%20test%20%28FAIR-2%29%20at%20school.%20Data%20on%20physical%20activity%2C%20media%20consumption%2C%20family%20eating%20habits%20and%20socio-economic%20status%20%28SES%29%20were%20collected%20from%20parents%20using%20questionnaires.%20Associations%20between%20attention%20and%20influencing%20factors%20were%20estimated%20using%20hierarchical%20linear%20regression.%20Analyses%20were%20adjusted%20for%20age%2C%20SES%2C%20and%20school%20type.%5CnRESULTS%3A%20Attending%20upper%20secondary%20schools%20%28%5Cu00dfadj%3D%2023.6%2C%20p%5Cu2009%3C%5Cu20090.001%29%20and%20having%20a%20higher%20SES%20%28%5Cu00df%3D%201.28%2C%20p%5Cu2009%3C%5Cu20090.001%29%20was%20associated%20with%20higher%20attention%20performance.%20Children%20doing%20leisure-time%20sports%20%28%5Cu00dfadj%3D%204.18%2C%20p%5Cu2009%3D%5Cu20090.046%29%20or%20reading%20books%20for%20at%20least%20one%20hour%5C%2Fweekday%20showed%20better%20attention%20performance%20%28%5Cu00dfadj%3D%203.8%2C%20p%5Cu2009%3D%5Cu20090.040%29.%20Attention%20performance%20was%20also%20better%20in%20children%20having%20no%20electronic%20devices%20in%20the%20bedroom%20%28%5Cu00dfadj%3D%2013.0%2C%20p%5Cu2009%3D%5Cu20090.005%29%20and%20in%20children%20whose%20parents%20limited%20their%20children%27s%20Internet%20access%20%28%5Cu00dfadj%3D%205.2%2C%20p%5Cu2009%3D%5Cu20090.012%29.%20We%20did%20not%20find%20any%20association%20between%20nutritional%20habits%20and%20attention%20performance.%5CnCONCLUSIONS%3A%20We%20found%20that%20fostering%20modifiable%20habits%20such%20as%20reading%20and%20physical%20activity%20could%20enhance%20attention%20performance.%20These%20findings%20have%20substantial%20implications%20for%20the%20development%20of%20prevention%20and%20intervention%20programs%20that%20aim%20to%20improve%20attention%20in%20schoolchildren.%20It%20is%20important%20to%20note%2C%20however%2C%20that%20social%20status%20as%20a%20hardly%20modifiable%20factor%20also%20impacts%20attention%20performance.%20Therefore%2C%20interventions%20should%20address%20personal%20habits%20in%20a%20systemic%20approach%20considering%20the%20child%27s%20social%20status.%5CnTRIAL%20REGISTRATION%3A%20The%20study%20is%20retrospectively%20registered%20with%20the%20German%20Clinical%20Trials%20Register%20%28DRKS00017317%2C%20registration%3A%2005-29-2019%29.%22%2C%22date%22%3A%222024-06-19%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1186%5C%2Fs12889-024-19059-8%22%2C%22ISSN%22%3A%221471-2458%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222024-08-27T12%3A26%3A19Z%22%7D%7D%2C%7B%22key%22%3A%223DCAUG36%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Sobek%20et%20al.%22%2C%22parsedDate%22%3A%222023-08%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3ESobek%2C%20Carolin%2C%20Peggy%20Ober%2C%20and%20Mandy%20Vogel.%20%26%23x201C%3BSchulen%20im%20%28Klima-%29Wandel%20%26%23×2013%3B%20Handlungsfelder.%26%23x201D%3B%20%3Ci%3EKinder-%20und%20Jugendmedizin%3C%5C%2Fi%3E%2023%2C%20no.%204%20%28August%202023%29%3A%20229%26%23×2013%3B34.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1055%5C%2Fa-2104-3463%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1055%5C%2Fa-2104-3463%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Schulen%20im%20%28Klima-%29Wandel%20%5Cu2013%20Handlungsfelder%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Carolin%22%2C%22lastName%22%3A%22Sobek%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Peggy%22%2C%22lastName%22%3A%22Ober%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%5D%2C%22abstractNote%22%3A%22Die%20Grundlagen%20bewusster%20umweltbezogener%20Einstellungen%20und%20Verhaltensweisen%20werden%20fr%5Cu00fch%20gelegt.%20Kinderg%5Cu00e4rten%20und%20Schulen%20als%20Orte%20des%20gemeinsamen%20Lebens%20und%20Lernens%20k%5Cu00f6nnen%20%5Cu2013%20neben%20dem%20Wissen%20%5Cu2013%20nachhaltige%20Normen%20und%20Werte%20vermitteln%20und%20festigen.%20Diese%20erm%5Cu00f6glichen%20es%20den%20Kindern%2C%20Ma%5Cu00dfnahmen%20gegen%20den%20Klimawandel%20zu%20verstehen%20und%20als%20selbstverst%5Cu00e4ndlich%20in%20ihrem%20Leben%20zu%20akzeptieren.%20Schulverpflegung%2C%20Schulweg%20und%20Schulg%5Cu00e4rten%20sind%20einige%20m%5Cu00f6gliche%20Handlungsfelder.%20Sie%20k%5Cu00f6nnen%20genutzt%20werden%2C%20Kinder%20f%5Cu00fcr%20umweltrelevante%20Themen%20zu%20sensibilisieren%20und%20so%20auch%20zuk%5Cu00fcnftigen%20Generationen%20eine%20lebenswerte%20Umwelt%20zu%20sichern.%22%2C%22date%22%3A%222023%5C%2F08%22%2C%22language%22%3A%22de%22%2C%22DOI%22%3A%2210.1055%5C%2Fa-2104-3463%22%2C%22ISSN%22%3A%221617-0288%2C%202567-577X%22%2C%22url%22%3A%22http%3A%5C%2F%5C%2Fwww.thieme-connect.de%5C%2FDOI%5C%2FDOI%3F10.1055%5C%2Fa-2104-3463%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222024-08-13T13%3A01%3A29Z%22%7D%7D%2C%7B%22key%22%3A%22PIT7XYLR%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Schmidt%20et%20al.%22%2C%22parsedDate%22%3A%222022-12%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3ESchmidt%2C%20Ricarda%2C%20Andreas%20Hiemisch%2C%20Wieland%20Kiess%2C%20Kai%20von%20Klitzing%2C%20Franziska%20Schlensog-Schuster%2C%20and%20Anja%20Hilbert.%20%26%23x201C%3BValidation%20Study%20on%20the%20Child%2C%20Adult%2C%20and%20Parent%20Version%20of%20the%20ARFID%20Module%202.0%20for%20the%20Eating%20Disorder%20Examination.%26%23x201D%3B%20%3Ci%3EThe%20International%20Journal%20of%20Eating%20Disorders%3C%5C%2Fi%3E%2055%2C%20no.%2012%20%28December%202022%29%3A%201708%26%23×2013%3B20.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1002%5C%2Feat.23805%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1002%5C%2Feat.23805%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Validation%20study%20on%20the%20child%2C%20adult%2C%20and%20parent%20version%20of%20the%20ARFID%20module%202.0%20for%20the%20Eating%20Disorder%20Examination%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ricarda%22%2C%22lastName%22%3A%22Schmidt%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andreas%22%2C%22lastName%22%3A%22Hiemisch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Kai%22%2C%22lastName%22%3A%22von%20Klitzing%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Franziska%22%2C%22lastName%22%3A%22Schlensog-Schuster%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anja%22%2C%22lastName%22%3A%22Hilbert%22%7D%5D%2C%22abstractNote%22%3A%22OBJECTIVE%3A%20This%20study%20presents%20a%20psychometric%20evaluation%20of%20the%20avoidant%5C%2Frestrictive%20food%20intake%20disorder%20%28ARFID%29%20module%202.0%20for%20the%20Eating%20Disorder%20Examination%20%28EDE%29%2C%20its%20child%20%28ChEDE%29%2C%20and%20parent%20version.%20Within%20a%20pediatric%20sample%20seeking%20treatment%20for%20restrictive%20feeding%20or%20eating%20disorders%20and%20non-treatment-seeking%20controls%2C%20the%20module%27s%20interrater%20reliability%2C%20parent-child%20agreement%2C%20and%20its%20convergent%2C%20divergent%2C%20and%20discriminant%20validity%20were%20examined.%5CnMETHOD%3A%20The%20child%2C%20adult%2C%20and%5C%2For%20parent%20version%20of%20the%20German%20ARFID%20module%20was%20administered%20to%20N%5Cu00a0%3D%5Cu00a0176%20children%20and%20adolescents%20%280-17%5Cu2009years%29%20and%20their%20parents%2C%20as%20were%20the%20%28Ch%29EDE%2C%20well-established%20measures%20on%20food-avoidance%20behaviors%2C%20food%20variety%2C%20and%20body%20esteem%2C%20and%20objective%20anthropometric%20measures.%5CnRESULTS%3A%20Across%20all%20versions%20of%20the%20ARFID%20module%2C%20substantial%20to%20almost%20perfect%20interrater%20reliability%20was%20shown.%20Parent-child%20agreement%20for%20ARFID%20diagnosis%20was%20substantial.%20Based%20on%20medium-to-large%20associations%20between%20interview-assessed%20avoidant%5C%2Frestrictive%20food%20intake%20and%20questionnaire-assessed%20food-avoidance%20behaviors%2C%20food%20variety%2C%20and%20objective%20weight%20status%2C%20the%20module%20showed%20high%20convergent%20validity%2C%20especially%20for%20the%20child%20and%20parent%20version.%20Low%20associations%20of%20avoidant%5C%2Frestrictive%20food%20intake%20with%20weight%20and%20shape%20concern%20demonstrated%20divergent%20validity.%20Individuals%20with%20ARFID%20differed%20significantly%20from%20those%20with%20anorexia%20nervosa%20and%20individually%20matched%20controls%20in%20a%20range%20of%20clinical%20characteristics%2C%20indicating%20discriminant%20validity.%5CnDISCUSSION%3A%20This%20comprehensive%20validation%20supports%20the%20EDE%20ARFID%20module%20to%20be%20a%20valuable%20measure%20for%20the%20assessment%20and%20diagnosis%20of%20ARFID%20in%200-17-year-olds%20based%20on%20self-%20and%20parent-report.%20Validation%20of%20the%20ARFID%20module%20against%20other%20interview-based%20measures%20on%20ARFID%20and%20its%20evaluation%20in%20an%20adult%20sample%20are%20pending.%5CnPUBLIC%20SIGNIFICANCE%3A%20Based%20on%20good%20reliability%20and%20validity%20of%20the%20avoidant%5C%2Frestrictive%20food%20intake%20disorder%20%28ARFID%29%20module%20for%20the%20Eating%20Disorder%20Examination%20%28EDE%29%20in%20its%20child%2C%20adult%2C%20and%20parent%20version%2C%20the%20present%20study%20paves%20the%20way%20for%20the%20clinical%20and%20research%20use%20of%20the%20interview-based%20EDE%20ARFID%20module%20for%20assessing%20ARFID%20across%20childhood%20and%20adolescence.%22%2C%22date%22%3A%222022-12%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1002%5C%2Feat.23805%22%2C%22ISSN%22%3A%221098-108X%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-24T11%3A24%3A41Z%22%7D%7D%2C%7B%22key%22%3A%227AC83PIF%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Sobek%20et%20al.%22%2C%22parsedDate%22%3A%222021-12%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3ESobek%2C%20Carolin%2C%20Peggy%20Ober%2C%20Sarah%20Abel%2C%20Ulrike%20Spielau%2C%20Wieland%20Kiess%2C%20Christof%20Meigen%2C%20Tanja%20Poulain%2C%20Ulrike%20Igel%2C%20Mandy%20Vogel%2C%20and%20Tobias%20Lipek.%20%26%23x201C%3BPurchasing%20Behavior%2C%20Setting%2C%20Pricing%2C%20Family%3A%20Determinants%20of%20School%20Lunch%20Participation.%26%23x201D%3B%20%3Ci%3ENutrients%3C%5C%2Fi%3E%2013%2C%20no.%2012%20%28December%202021%29%3A%204209.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Fnu13124209%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Fnu13124209%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Purchasing%20Behavior%2C%20Setting%2C%20Pricing%2C%20Family%3A%20Determinants%20of%20School%20Lunch%20Participation%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Carolin%22%2C%22lastName%22%3A%22Sobek%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Peggy%22%2C%22lastName%22%3A%22Ober%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Sarah%22%2C%22lastName%22%3A%22Abel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ulrike%22%2C%22lastName%22%3A%22Spielau%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christof%22%2C%22lastName%22%3A%22Meigen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ulrike%22%2C%22lastName%22%3A%22Igel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tobias%22%2C%22lastName%22%3A%22Lipek%22%7D%5D%2C%22abstractNote%22%3A%22Despite%20growing%20school%20lunch%20availability%20in%20Germany%2C%20its%20utilization%20is%20still%20low%2C%20and%20students%20resort%20to%20unhealthy%20alternatives.%20We%20investigated%20predictors%20of%20school%20lunch%20participation%20and%20reasons%20for%20nonparticipation%20in%201215%20schoolchildren.%20Children%20reported%20meal%20habits%2C%20parents%20provided%20family-related%20information%20%28like%20socioeconomic%20status%29%2C%20and%20anthropometry%20was%20conducted%20on-site%20in%20schools.%20Associations%20between%20school%20lunch%20participation%20and%20family-related%20predictors%20were%20estimated%20using%20logistic%20regression%20controlling%20for%20age%20and%20gender%20if%20necessary.%20School%20was%20added%20as%20a%20random%20effect.%20School%20lunch%20participation%20was%20primarily%20associated%20with%20family%20factors.%20While%20having%20breakfast%20on%20schooldays%20was%20positively%20associated%20with%20school%20lunch%20participation%20%28ORadj%20%3D%202.20%2C%20p%20%3D%200.002%29%2C%20lower%20secondary%20schools%20%28ORadj%20%3D%200.52%2C%20p%20%26lt%3B%200.001%29%20and%20low%20SES%20%28ORadj%20%3D%200.25%2C%20p%20%26lt%3B%200.001%29%20were%20negatively%20associated.%20The%20main%20reasons%20for%20nonparticipation%20were%20school-%20and%20lunch-related%20factors%20%28taste%2C%20time%20constraints%2C%20pricing%29.%20Parents%20reported%20pricing%20as%20crucial%20a%20reason%20as%20an%20unpleasant%20taste%20for%20nonparticipation.%20Nonparticipants%20bought%20sandwiches%20and%20energy%20drinks%20significantly%20more%20often%20on%20school%20days%2C%20whereas%20participants%20were%20less%20often%20affected%20by%20overweight%20%28OR%20%3D%200.66%2C%20p%20%3D%200.043%29.%20Our%20data%20stress%20school-%20and%20lunch-related%20factors%20as%20an%20important%20opportunity%20to%20foster%20school%20lunch%20utilization.%22%2C%22date%22%3A%222021%5C%2F12%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.3390%5C%2Fnu13124209%22%2C%22ISSN%22%3A%22%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.mdpi.com%5C%2F2072-6643%5C%2F13%5C%2F12%5C%2F4209%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-07T07%3A01%3A24Z%22%7D%7D%2C%7B%22key%22%3A%22XLL99XYD%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Menzel%20et%20al.%22%2C%22parsedDate%22%3A%222021-10%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EMenzel%2C%20Philipp%2C%20Mandy%20Vogel%2C%20Sean%20Austin%2C%20Norbert%20Sprenger%2C%20Nico%20Grafe%2C%20Cornelia%20Hilbert%2C%20Anne%20Jurkutat%2C%20Wieland%20Kiess%2C%20and%20Aristea%20Binia.%20%26%23x201C%3BConcentrations%20of%20Oligosaccharides%20in%20Human%20Milk%20and%20Child%20Growth.%26%23x201D%3B%20%3Ci%3EBMC%20Pediatrics%3C%5C%2Fi%3E%2021%2C%20no.%201%20%28October%202021%29%3A%20481.%20%3Ca%20class%3D%27zp-ItemURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs12887-021-02953-0%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs12887-021-02953-0%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Concentrations%20of%20Oligosaccharides%20in%20Human%20Milk%20and%20Child%20Growth%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Philipp%22%2C%22lastName%22%3A%22Menzel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Sean%22%2C%22lastName%22%3A%22Austin%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Norbert%22%2C%22lastName%22%3A%22Sprenger%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Nico%22%2C%22lastName%22%3A%22Grafe%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Cornelia%22%2C%22lastName%22%3A%22Hilbert%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anne%22%2C%22lastName%22%3A%22Jurkutat%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Aristea%22%2C%22lastName%22%3A%22Binia%22%7D%5D%2C%22abstractNote%22%3A%22Background%3A%5Cu2002%20The%20relationship%20between%20human%20milk%20oligosaccharides%20%28HMO%29%20and%20child%20growth%20has%20been%20investigated%20only%20insufficiently%20with%20ambiguous%20results.%20Therefore%2C%20this%20study%20examines%20potential%20influencing%20factors%20of%20HMO%20concentrations%20and%20how%20HMO%20are%20associated%20with%20child%20growth%20parameters.%5CnMethods%3A%5Cu2002%20Milk%20samples%20from%20the%20German%20LIFE%20Child%20cohort%20of%20healthy%20children%20were%20analyzed%20for%209%20HMO.%20Putative%20associations%20with%20maternal%20and%20child%20cofactors%20and%20child%20height%2C%20head%20circumference%20and%20BMI%20between%203%5Cu2009months%20and%207%5Cu2009years%20of%20age%20were%20examined.%20Secretor%20status%2C%20defined%20as%20the%20presence%20of%202%5Cu2032-fucosyllactose%2C%20was%20investigated%20for%20associations%20with%20infant%20outcomes.%5CnResults%3A%5Cu2002%20Our%20population%20consisted%20of%2021%20%2814.7%25%29%20non-secretor%20and%20122%20%2885.3%25%29%20secretor%20mothers.%20Maternal%20age%20was%20significantly%20associated%20with%20higher%203%5Cu2032SL%20concentrations%3B%20gestational%20age%20was%20associated%20with%20LNT%2C%206%5Cu2032SL%20and%20LNFP-I.%20Pre-pregnancy%20BMI%20was%20negatively%20associated%20with%20LNnT%20only%20in%20non-secretors.%20The%20growth%20velocity%20of%20non-secretors%5Cu2019%20children%20was%20inversely%20associated%20with%20LNnT%20at%203%5Cu2009months%20to%201%5Cu2009year%20%28R%5Cu2009%3D%5Cu20090.95%20%5B0.90%2C%200.99%5D%2C%20p%5Cu2009%3D%5Cu20090.014%29%2C%201%20to%202%5Cu2009years%20%28R%5Cu2009%3D%5Cu20090.80%20%5B0.72%2C%200.88%5D%2C%20p%5Cu2009%3C%5Cu20090.001%29%20and%205%20to%206%5Cu2009years%20%28R%5Cu2009%3D%5Cu20090.71%20%5B0.57%2C%200.87%5D%2C%20p%5Cu2009%3D%5Cu20090.002%29.%202%5Cu2019FL%20was%20negatively%20associated%20with%20BMI%20consistently%2C%20reaching%20statistical%20significance%20at%203%5Cu2009months%20and%204%20and%205%5Cu2009years.%20Children%20of%20non-secretors%20showed%20higher%20BMI%20at%203%5Cu2009months%2C%206%5Cu2009months%2C%20and%203%2C%206%2C%20and%207%5Cu2009years%20of%20age.%5CnConclusion%3A%5Cu2002%20We%20found%20that%20some%20associations%20between%20HMO%20and%20infant%20growth%20may%20extend%20beyond%20the%20infancy%20and%20breastfeeding%20periods.%20They%20highlight%20the%20importance%20of%20both%20maternal%20and%20infant%20parameters%20in%20the%20understanding%20of%20the%20underlying%20associations.%22%2C%22date%22%3A%222021%5C%2F10%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1186%5C%2Fs12887-021-02953-0%22%2C%22ISSN%22%3A%22%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs12887-021-02953-0%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-07T07%3A01%3A38Z%22%7D%7D%2C%7B%22key%22%3A%22SAGIDNQR%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Poulain%20et%20al.%22%2C%22parsedDate%22%3A%222021-09%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EPoulain%2C%20Tanja%2C%20Ulrike%20Spielau%2C%20Mandy%20Vogel%2C%20Anne%20Dathan-Stumpf%2C%20Antje%20K%26%23xF6%3Brner%2C%20and%20Wieland%20Kiess.%20%26%23x201C%3BChanges%20in%20Diet%20from%20Pregnancy%20to%20One%20Year%20After%20Birth%3A%20A%20Longitudinal%20Study.%26%23x201D%3B%20%3Ci%3EBMC%20Pregnancy%20and%20Childbirth%3C%5C%2Fi%3E%2021%2C%20no.%201%20%28September%202021%29%3A%20600.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs12884-021-04038-3%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs12884-021-04038-3%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Changes%20in%20Diet%20from%20Pregnancy%20to%20One%20Year%20After%20Birth%3A%20A%20Longitudinal%20Study%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ulrike%22%2C%22lastName%22%3A%22Spielau%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anne%22%2C%22lastName%22%3A%22Dathan-Stumpf%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%5D%2C%22abstractNote%22%3A%22BACKGROUND%3A%20Pregnancy%20and%20the%20first%20year%20after%20giving%20birth%20are%20marked%20by%20physiological%20and%20psychological%20changes.%20While%20it%20is%20well%20known%20that%20energy%20requirements%20change%20during%20this%20time%2C%20the%20question%20of%20how%20a%20woman%27s%20diet%20actually%20changes%20from%20pregnancy%20until%201%5Cu00a0year%20postpartum%20has%20been%20left%20virtually%20unexplored.%20The%20present%20study%20employs%20a%20longitudinal%20design%20to%20investigate%20these%20changes.%5CnMETHODS%3A%20Data%20were%20collected%20within%20the%20framework%20of%20the%20LIFE%20Child%20study%20%28Leipzig%2C%20Germany%29.%20The%20diet%20composition%20and%20culture%20of%20eating%20of%20110%20women%20were%20assessed%20at%203%20time%20points%3A%20in%20the%2024th%20week%20of%20pregnancy%2C%203%5Cu2009months%20after%20giving%20birth%20%28breastfeeding%20period%29%2C%20and%2012%5Cu2009months%20after%20giving%20birth%20%28after%20weaning%29.%20We%20assessed%20differences%20in%20nutritional%20health%20%28Nutritional%20Health%20Score%2C%20NHS%29%20and%20the%20consumption%20of%20different%20food%20items%20at%20each%20of%20these%20time%20points.%20We%20also%20investigated%20associations%20between%20nutritional%20health%20and%20age%2C%20socio-economic%20status%20%28SES%29%2C%20BMI%20before%20pregnancy%2C%20and%20previous%20births%20at%20all%20three%20time%20points.%5CnRESULTS%3A%20The%20analyses%20revealed%20high%20correlations%20in%20the%20NHS%20values%20between%20the%20three%20time%20points%20%28rhot0%5C%2Ft1%5Cu2009%3D%5Cu2009.55%2C%20rhot0%5C%2Ft2%5Cu2009%3D%5Cu2009.60%29.%20On%20average%2C%20nutritional%20health%20was%20lower%20in%20the%20breastfeeding%20period%20than%20during%20pregnancy.%20In%20more%20detail%2C%20women%20reported%20less%20healthy%20levels%20of%20treats%20and%20white%20bread%20consumption%20and%20a%20higher%20frequency%20of%20snacking%20in%20the%20breastfeeding%20period%20than%20during%20pregnancy.%20In%20contrast%2C%20overall%20nutritional%20health%20did%20not%20differ%20significantly%20between%20pregnancy%20and%20the%20time%20after%20weaning.%20Increased%20age%20was%20associated%20with%20a%20healthier%20diet%20during%20pregnancy%2C%20and%20a%20high%20SES%20was%20associated%20with%20healthier%20diet%20after%20weaning.%20Furthermore%2C%20the%20increase%20in%20nutritional%20health%20from%20the%20breastfeeding%20period%20to%20the%20time%20after%20weaning%20was%20significantly%20stronger%20in%20women%20with%20a%20higher%20BMI.%20We%20observed%20no%20significant%20associations%20between%20dietary%20nutritional%20health%20and%20previous%20births.%5CnCONCLUSIONS%3A%20The%20present%20findings%20suggest%20that%20higher%20energy%20requirements%20in%20the%20breastfeeding%20period%20are%20met%20by%20consuming%20high-calorie%20and%20unhealthy%20food%20products%20rather%20than%20healthy%20and%20nutrient-rich%20food.%20Young%20mothers%20should%20be%20supported%20in%20taking%20care%20of%20their%20own%20nutritional%20health%20during%20the%20challenging%20time%20of%20breastfeeding%20and%20caring%20for%20a%20newborn%20child.%22%2C%22date%22%3A%222021-09%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1186%5C%2Fs12884-021-04038-3%22%2C%22ISSN%22%3A%221471-2393%22%2C%22url%22%3A%22http%3A%5C%2F%5C%2Forgid.org%5C%2F10.1186%5C%2Fs12884-021-04038-3%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-07T07%3A01%3A32Z%22%7D%7D%2C%7B%22key%22%3A%22Z3EW48N5%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Spielau%20et%20al.%22%2C%22parsedDate%22%3A%222021-06%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3ESpielau%2C%20Ulrike%2C%20Mandy%20Vogel%2C%20Antje%20K%26%23xF6%3Brner%2C%20Wieland%20Kiess%2C%20and%20Tanja%20Poulain.%20%26%23x201C%3BComposition%20and%20Culture%20of%20Eating%20%28Cocu%29%20Pregnancy%3A%20A%20New%20Short%20Questionnaire%20to%20Evaluate%20Diet%20Composition%20and%20Culture%20of%20Eating%20During%20Pregnancy.%26%23x201D%3B%20%3Ci%3EPublic%20Health%20Nutrition%3C%5C%2Fi%3E%2024%2C%20no.%2018%20%28June%202021%29%3A%206227%26%23×2013%3B35.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1017%5C%2FS1368980021002445%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1017%5C%2FS1368980021002445%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Composition%20and%20Culture%20of%20Eating%20%28cocu%29%20Pregnancy%3A%20A%20New%20Short%20Questionnaire%20to%20Evaluate%20Diet%20Composition%20and%20Culture%20of%20Eating%20During%20Pregnancy%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ulrike%22%2C%22lastName%22%3A%22Spielau%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%5D%2C%22abstractNote%22%3A%22Objective%3A%5CnThe%20project%20aimed%20to%20validate%20a%20short%20questionnaire%20%28CoCu%20pregnancy%20%5Cu2013%20Composition%20and%20Culture%20of%20Eating%20during%20pregnancy%29%20and%20to%20investigate%20associations%20with%20age%20and%20socio-economic%20status%20%28SES%29.%5Cn%5Cn%5CnDesign%3A%5CnThe%20questionnaire%20was%20developed%20according%20to%20the%20validated%20CoCu%20for%20children%20and%20adolescents%20containing%20a%20diet%20composition%20%28fourteen%20items%29%20and%20a%20culture%20of%20eating%20part%20%28six%20items%29.%20A%20Nutritional%20Health%20Score%20%28NHS%29%20was%20calculated%20based%20on%20diet%20composition%20%28%5Cu2013120%20and%20%2B120%2C%20with%20higher%20scores%20indicating%20healthier%20diets%29.%20The%20validity%20was%20assessed%20by%20comparing%20answers%20in%20CoCu%20pregnancy%20with%20a%20FFQ.%20In%20a%20subsample%20%28n%2097%29%2C%20we%20assessed%20the%20percentage%20of%20having%20chosen%20the%20same%20%28or%20adjacent%29%20response%20categories%20in%20the%2024th%20and%2036th%20week%20of%20pregnancy%20%28wp%29.%5Cn%5Cn%5CnSetting%3A%5CnData%20were%20collected%20within%20the%20LIFE%20Child%20study%20in%20Leipzig%2C%20Germany.%5Cn%5Cn%5CnParticipants%3A%5CnWe%20evaluated%20430%20questionnaires%20of%20pregnant%20women%20%2824th%20wp%29.%5Cn%5Cn%5CnResults%3A%5CnThe%20results%20indicated%20a%20healthy%20diet%20in%20the%20present%20sample%20%28NHS%20at%2024th%20wp%20%3D%2049%5Cu00b774%20%2895%20%25%20CI%2047%5Cu00b727%2C%2052%5Cu00b722%29%29.%20The%20analyses%20revealed%20significant%20positive%20correlations%20between%20CoCu%20and%20FFQ%20%28rho%20ranging%20from%200%5Cu00b732%20to%200%5Cu00b761%29.%20For%20each%20food%20item%2C%20%3E90%20%25%20of%20women%20had%20chosen%20the%20same%20%2850%5Cu201360%20%25%29%20or%20adjacent%20response%20categories%20in%20the%2024th%20and%2036th%20wp.%20The%20analysis%20revealed%20associations%20of%20the%20NHS%20with%20age%20%28%5Cu03b2%20%3D%200%5Cu00b711%2C%20P%20%3D%200%5Cu00b7027%29%2C%20SES%20%28%5Cu03b2%20%3D%200%5Cu00b721%2C%20P%20%3C%200%5Cu00b7001%29%2C%20snacking%20%28%5Cu03b2%20%3D%20%5Cu20130%5Cu00b724%2C%20P%20%3C%200%5Cu00b7001%29%20and%20media%20use%20%28%5Cu03b2%20%3D%20%5Cu20130%5Cu00b718%2C%20P%20%3C%200%5Cu00b7001%29.%5Cn%5Cn%5CnConclusions%3A%5CnThe%20questionnaire%20represents%20a%20useful%20tool%20for%20surveying%20the%20diets%20during%20pregnancy%20for%20research%20and%20clinical%20practice.%22%2C%22date%22%3A%222021-06%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1017%5C%2FS1368980021002445%22%2C%22ISSN%22%3A%221368-9800%2C%201475-2727%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.cambridge.org%5C%2Fcore%5C%2Fjournals%5C%2Fpublic-health-nutrition%5C%2Farticle%5C%2Fabs%5C%2Fcomposition-and-culture-of-eating-cocu-pregnancy-a-new-short-questionnaire-to-evaluate-diet-composition-and-culture-of-eating-during-pregnancy%5C%2FE2F71224A497114A5F5942E325665D57%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-24T13%3A14%3A27Z%22%7D%7D%2C%7B%22key%22%3A%22NZSHI553%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Ober%20et%20al.%22%2C%22parsedDate%22%3A%222021-04%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EOber%2C%20Peggy%2C%20Carolin%20Sobek%2C%20Nancy%20Stein%2C%20Ulrike%20Spielau%2C%20Sarah%20Abel%2C%20Wieland%20Kiess%2C%20Christof%20Meigen%2C%20et%20al.%20%26%23x201C%3BAnd%20yet%20Again%3A%20Having%20Breakfast%20Is%20Positively%20Associated%20with%20Lower%20Bmi%20and%20Healthier%20General%20Eating%20Behavior%20in%20Schoolchildren.%26%23x201D%3B%20%3Ci%3ENutrients%3C%5C%2Fi%3E%2013%2C%20no.%204%20%28April%202021%29%3A%201351.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Fnu13041351%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Fnu13041351%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22And%20yet%20Again%3A%20Having%20Breakfast%20Is%20Positively%20Associated%20with%20Lower%20Bmi%20and%20Healthier%20General%20Eating%20Behavior%20in%20Schoolchildren%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Peggy%22%2C%22lastName%22%3A%22Ober%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Carolin%22%2C%22lastName%22%3A%22Sobek%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Nancy%22%2C%22lastName%22%3A%22Stein%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ulrike%22%2C%22lastName%22%3A%22Spielau%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Sarah%22%2C%22lastName%22%3A%22Abel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christof%22%2C%22lastName%22%3A%22Meigen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ulrike%22%2C%22lastName%22%3A%22Igel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tobias%22%2C%22lastName%22%3A%22Lipek%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%5D%2C%22abstractNote%22%3A%22Given%20the%20high%20prevalence%20of%20childhood%20overweight%2C%20school-based%20programs%20aiming%20at%20nutritional%20behavior%20may%20be%20a%20good%20starting%20point%20for%20community-based%20interventions.%20Therefore%2C%20we%20investigated%20associations%20between%20school-related%20meal%20patterns%20and%20weight%20status%20in%201215%20schoolchildren.%20Anthropometry%20was%20performed%20on-site%20in%20schools.%20Children%20reported%20their%20meal%20habits%2C%20and%20parents%20provided%20family-related%20information%20via%20questionnaires.%20Associations%20between%20nutritional%20behavior%20and%20weight%20status%20were%20estimated%20using%20hierarchical%20linear%20and%20logistic%20regression.%20Analyses%20were%20adjusted%20for%20age%2C%20socio%5Cu2013economic%20status%2C%20school%20type%2C%20migration%20background%2C%20and%20parental%20weight%20status.%20Having%20breakfast%20was%20associated%20with%20a%20lower%20BMI-SDS%20%28%5Cu03b2adj%20%3D%20%5Cu22120.51%2C%20p%20%3D%200.004%29%20and%20a%20lower%20risk%20of%20being%20overweight%20%28ORadj%20%3D%200.30%2C%20p%20%3D%200.009%29%2C%20while%20having%20two%20breakfasts%20resulting%20in%20stronger%20associations%20%28BMI-SDS%3A%20%5Cu03b2adj%20%3D%20%5Cu22120.66%2C%20p%20%26lt%3B%200.001%3B%20risk%20of%20overweight%3A%20ORadj%20%3D%200.22%2C%20p%20%3D%200.001%29.%20Likewise%2C%20children%20who%20regularly%20skipped%20breakfast%20on%20school%20days%20showed%20stronger%20associations%20%28BMI-SDS%3A%20%5Cu03b2%20%3D%200.49%2C%20p%20%26lt%3B%200.001%3B%20risk%20of%20overweight%3A%20OR%20%3D%203.29%2C%20p%20%26lt%3B%200.001%29%20than%20children%20who%20skipped%20breakfast%20only%20occasionally%20%28BMI-SDS%3A%20%5Cu03b2%20%3D%200.43%2C%20p%20%26lt%3B%200.001%3B%20risk%20of%20overweight%3A%20OR%20%3D%202.72%2C%20p%20%3D%200.032%29.%20The%20associations%20persisted%20after%20controlling%20for%20parental%20SES%20and%20weight%20status.%20Therefore%2C%20our%20data%20confirm%20the%20school%20setting%20as%20a%20suitable%20starting%20point%20for%20community-based%20interventions%20and%20may%20underline%20the%20necessity%20of%20national%20programs%20providing%20free%20breakfast%20and%20lunch%20to%20children.%22%2C%22date%22%3A%222021%5C%2F4%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.3390%5C%2Fnu13041351%22%2C%22ISSN%22%3A%22%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.mdpi.com%5C%2F2072-6643%5C%2F13%5C%2F4%5C%2F1351%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-07T07%3A01%3A36Z%22%7D%7D%2C%7B%22key%22%3A%22JRR6487S%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Schmidt%20et%20al.%22%2C%22parsedDate%22%3A%222021-01%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3ESchmidt%2C%20Ricarda%2C%20Andreas%20Hiemisch%2C%20Wieland%20Kiess%2C%20Kai%20von%20Klitzing%2C%20Franziska%20Schlensog-Schuster%2C%20and%20Anja%20Hilbert.%20%26%23x201C%3BMacro-%20and%20Micronutrient%20Intake%20in%20Children%20with%20Avoidant%5C%2FRestrictive%20Food%20Intake%20Disorder.%26%23x201D%3B%20%3Ci%3ENutrients%3C%5C%2Fi%3E%2013%2C%20no.%202%20%28January%202021%29%3A%20400.%20%3Ca%20class%3D%27zp-ItemURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Fnu13020400%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Fnu13020400%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Macro-%20and%20Micronutrient%20Intake%20in%20Children%20with%20Avoidant%5C%2FRestrictive%20Food%20Intake%20Disorder%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ricarda%22%2C%22lastName%22%3A%22Schmidt%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andreas%22%2C%22lastName%22%3A%22Hiemisch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Kai%22%2C%22lastName%22%3A%22von%20Klitzing%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Franziska%22%2C%22lastName%22%3A%22Schlensog-Schuster%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anja%22%2C%22lastName%22%3A%22Hilbert%22%7D%5D%2C%22abstractNote%22%3A%22Although%20case%20studies%20in%20avoidant%5C%2Frestrictive%20food%20intake%20disorder%20%28ARFID%29%20indicate%20severe%20nutritional%20deficiencies%20in%20those%20with%20a%20highly%20limited%20amount%20or%20variety%20of%20food%20intake%2C%20systematic%20analyses%20on%20food%20intake%20in%20treatment-seeking%20children%20and%20adolescents%20with%20ARFID%20are%20lacking.%20Within%20this%20study%2C%20n%20%3D%2020%20patients%20with%20an%20interview-based%20diagnosis%20of%20ARFID%20%280-17%20years%29%20were%20included%20and%20compared%20to%20n%20%3D%2020%20healthy%20controls%20individually%20matched%20for%20age%20and%20sex.%20Children%20or%20parents%20completed%20three-day%20food%20diaries%20and%20a%20food%20list.%20Macronutrient%2C%20vitamin%2C%20and%20mineral%20supply%20was%20determined%20based%20on%20the%20percentage%20of%20their%20recommended%20intake.%20The%20results%20showed%20a%20significantly%20lower%20total%20energy%20and%20protein%20intake%20in%20ARFID%20versus%20controls%2C%20with%20trends%20for%20lower%20fat%20and%20carbohydrate%20intake.%20ARFID%20subtypes%20of%20limited%20amount%20versus%20variety%20of%20food%20intake%20significantly%20differed%20in%20macro-%2C%20but%20not%20micronutrient%20intake.%20Those%20with%20ARFID%20met%20only%2020%25-30%25%20of%20the%20recommended%20intake%20for%20most%20vitamins%20and%20minerals%2C%20with%20significantly%20lower%20intake%20relative%20to%20controls%20for%20vitamin%20B1%2C%20B2%2C%20C%2C%20K%2C%20zinc%2C%20iron%2C%20and%20potassium.%20Variety%20of%20food%20intake%20was%20significantly%20reduced%20in%20ARFID%20versus%20controls%20in%20all%20food%20groups%20except%20carbohydrates.%20This%20study%20demonstrated%20that%20ARFID%20goes%20along%20with%20reduced%20everyday%20life%20macro-%20and%20micronutrient%20intake%2C%20which%20may%20increase%20the%20risk%20for%20developmental%20and%20health%20problems.%20Future%20studies%20additionally%20assessing%20serum%20nutrient%20levels%20in%20a%20larger%20sample%20may%20further%20explore%20differences%20in%20food%20intake%20across%20diverse%20ARFID%20presentations.%22%2C%22date%22%3A%222021-01%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.3390%5C%2Fnu13020400%22%2C%22ISSN%22%3A%222072-6643%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Fnu13020400%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-07T07%3A01%3A26Z%22%7D%7D%2C%7B%22key%22%3A%228S9Z73TW%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Poulain%20et%20al.%22%2C%22parsedDate%22%3A%222020%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EPoulain%2C%20Tanja%2C%20Mandy%20Vogel%2C%20Christof%20Meigen%2C%20Ulrike%20Spielau%2C%20Andreas%20Hiemisch%2C%20and%20Wieland%20Kiess.%20%26%23x201C%3BParent-Child%20Agreement%20in%20Different%20Domains%20of%20Child%20Behavior%20and%20Health.%26%23x201D%3B%20%3Ci%3EPloS%20One%3C%5C%2Fi%3E%2015%2C%20no.%204%20%282020%29%3A%20e0231462.%20%3Ca%20class%3D%27zp-ItemURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1371%5C%2Fjournal.pone.0231462%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1371%5C%2Fjournal.pone.0231462%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Parent-Child%20Agreement%20in%20Different%20Domains%20of%20Child%20Behavior%20and%20Health%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christof%22%2C%22lastName%22%3A%22Meigen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ulrike%22%2C%22lastName%22%3A%22Spielau%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andreas%22%2C%22lastName%22%3A%22Hiemisch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%5D%2C%22abstractNote%22%3A%22AIM%3A%20The%20present%20study%20aimed%20to%20investigate%20and%20compare%20parent-child%20agreement%20in%20different%20domains%20of%20child%20health%20and%20behavior.%5CnMETHODS%3A%20Data%20were%20collected%20between%202011%20and%202019%20within%20the%20framework%20of%20the%20LIFE%20Child%20study%20%28Germany%29.%20Different%20subgroups%20of%2010-%20to%2012-year-old%20children%20and%20their%20parents%20%28n%20%28max%29%20%3D%20692%29%20completed%20questionnaires%20on%20several%20health%20behaviors%20%28diet%2C%20media%20use%2C%20physical%20activity%2C%20sleep%29%2C%20parameters%20of%20health%20%28behavioral%20strengths%20and%20difficulties%2C%20psychosomatic%20complaints%29%2C%20and%20school%20grades.%20Agreement%20between%20child%20and%20parent%20reports%20was%20evaluated%20using%20weighted%20kappa%20coefficients.%20Furthermore%2C%20the%20frequencies%20of%20different%20types%20of%20%28dis%29agreement%20%28parent%20report%20%3E%20child%20report%2C%20same%20response%2C%20child%20report%20%3E%20parent%20report%29%20were%20assessed%20and%20checked%20for%20associations%20with%20child%20or%20parent%20gender.%5CnRESULTS%3A%20Agreement%20between%20child%20and%20parent%20reports%20varied%20from%20low%20to%20almost%20perfect%2C%20with%20the%20greatest%20levels%20of%20agreement%20for%20school%20grades%20and%20organized%20physical%20activity%2C%20and%20the%20lowest%20for%20dizziness%2C%20sleep%20duration%2C%20and%20the%20consumption%20of%20potatoes.%20Child%20gender%20had%20no%20significant%20effect%20on%20parent-child%20agreement.%20In%20contrast%2C%20the%20findings%20suggest%20that%20parent%20gender%20had%20some%20effect%20on%20agreement%20levels%2C%20with%20higher%20agreement%20for%20certain%20psychosomatic%20complaints%20when%20parent%20reports%20were%20completed%20by%20the%20mother%2C%20and%20higher%20agreement%20for%20white%20bread%20consumption%20if%20they%20were%20completed%20by%20the%20father.%20For%20some%20of%20the%20questionnaire%20items%20%28especially%20those%20relating%20to%20behavioral%20difficulties%20and%20psychosomatic%20complaints%2C%20but%20also%20to%20the%20consumption%20of%20individual%20food%20products%20and%20mobile%20phone%20use%29%2C%20the%20type%20of%20%28dis%29agreement%20differed%20depending%20on%20child%20or%20parent%20gender.%5CnCONCLUSIONS%3A%20The%20findings%20suggest%20that%20the%20perceptions%20and%20reporting%20strategies%20of%20children%20and%20their%20parents%20can%20diverge%20considerably%2C%20in%20particular%20for%20behavior%20that%20is%20not%20easily%20observable%20or%20measurable.%22%2C%22date%22%3A%222020%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1371%5C%2Fjournal.pone.0231462%22%2C%22ISSN%22%3A%221932-6203%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1371%5C%2Fjournal.pone.0231462%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-24T11%3A05%3A20Z%22%7D%7D%2C%7B%22key%22%3A%22YQVV88KP%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Schmidt%20et%20al.%22%2C%22parsedDate%22%3A%222019-10%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3ESchmidt%2C%20Ricarda%2C%20Andreas%20Hiemisch%2C%20Wieland%20Kiess%2C%20and%20Anja%20Hilbert.%20%26%23x201C%3BInteraction%20Effects%20of%20Child%20Weight%20Status%20and%20Parental%20Feeding%20Practices%20on%20Children%26%23×2019%3Bs%20Eating%20Disorder%20Symptomatology.%26%23x201D%3B%20%3Ci%3ENutrients%3C%5C%2Fi%3E%2011%2C%20no.%2010%20%28October%202019%29%3A%202433.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Fnu11102433%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Fnu11102433%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Interaction%20Effects%20of%20Child%20Weight%20Status%20and%20Parental%20Feeding%20Practices%20on%20Children%27s%20Eating%20Disorder%20Symptomatology%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ricarda%22%2C%22lastName%22%3A%22Schmidt%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andreas%22%2C%22lastName%22%3A%22Hiemisch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anja%22%2C%22lastName%22%3A%22Hilbert%22%7D%5D%2C%22abstractNote%22%3A%22%281%29%20Background%3A%20Research%20on%20parental%20feeding%20practices%20and%20non-normative%20eating%20behavior%20including%20loss%20of%20control%20%28LOC%29%20eating%20and%20eating%20disorder%20psychopathology%20indicated%20separate%20associations%20of%20these%20variables%20with%20child%20weight%20status%2C%20especially%20in%20early%20childhood.%20This%20study%20cross-sectionally%20examined%20interaction%20effects%20of%20restriction%2C%20monitoring%2C%20pressure%20to%20eat%2C%20and%20children%27s%20weight%20status%20on%20disordered%20eating%20in%20children%20aged%208-13%20years.%20%282%29%20Methods%3A%20A%20population-based%20sample%20of%20N%20%3D%20904%20children%20and%20their%20mothers%20completed%20the%20Eating%20Disorder%20Examination%20Questionnaire%20for%20Children%20and%20the%20Child%20Feeding%20Questionnaire.%20Child%20anthropometrics%20were%20objectively%20measured.%20Hierarchical%20linear%20and%20logistic%20regression%20analyses%20were%20conducted%20for%20cross-sectionally%20predicting%20global%20eating%20disorder%20psychopathology%20and%20recurrent%20LOC%20eating%20by%20feeding%20practices%20and%20child%20weight%20status%20for%20younger%20%288-10%20years%29%20and%20older%20%2811-13%20years%29%20ages.%20%283%29%20Results%3A%20Restriction%20x%20Child%20weight%20status%20significantly%20predicted%20global%20eating%20disorder%20psychopathology%20in%20younger%20children%20and%20recurrent%20LOC%20eating%20in%20older%20children.%20Monitoring%20x%20Child%20weight%20status%20significantly%20predicted%20eating%20disorder%20psychopathology%20in%20older%20children.%20A%20higher%20versus%20lower%20child%20weight%20status%20was%20associated%20with%20adverse%20eating%20behaviors%2C%20particularly%20in%20children%20with%20mothers%20reporting%20high%20restriction%20and%20monitoring.%20%284%29%20Conclusions%3A%20Detrimental%20associations%20between%20higher%20child%20weight%20status%20and%20child%20eating%20disorder%20symptomatology%20held%20especially%20true%20for%20children%20whose%20mothers%20strongly%20control%20child%20food%20intake.%22%2C%22date%22%3A%22Oct%2C%202019%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.3390%5C%2Fnu11102433%22%2C%22ISSN%22%3A%222072-6643%22%2C%22url%22%3A%22http%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Fnu11102433%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-24T11%3A23%3A27Z%22%7D%7D%2C%7B%22key%22%3A%22UKUKF749%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Eichler%20et%20al.%22%2C%22parsedDate%22%3A%222019-07%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EEichler%2C%20Janina%2C%20Ricarda%20Schmidt%2C%20Tanja%20Poulain%2C%20Andreas%20Hiemisch%2C%20Wieland%20Kiess%2C%20and%20Anja%20Hilbert.%20%26%23x201C%3BStability%2C%20Continuity%2C%20and%20Bi-Directional%20Associations%20of%20Parental%20Feeding%20Practices%20and%20Standardized%20Child%20Body%20Mass%20Index%20in%20Children%20from%202%20to%2012%20Years%20of%20Age.%26%23x201D%3B%20%3Ci%3ENutrients%3C%5C%2Fi%3E%2011%2C%20no.%208%20%28July%202019%29.%20%3Ca%20class%3D%27zp-ItemURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Fnu11081751%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Fnu11081751%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Stability%2C%20Continuity%2C%20and%20Bi-Directional%20Associations%20of%20Parental%20Feeding%20Practices%20and%20Standardized%20Child%20Body%20Mass%20Index%20in%20Children%20from%202%20to%2012%20Years%20of%20Age%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Janina%22%2C%22lastName%22%3A%22Eichler%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ricarda%22%2C%22lastName%22%3A%22Schmidt%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andreas%22%2C%22lastName%22%3A%22Hiemisch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anja%22%2C%22lastName%22%3A%22Hilbert%22%7D%5D%2C%22abstractNote%22%3A%22%281%29%20Background%3A%20Parental%20feeding%20practices%20are%20related%20to%20child%20body%20mass%20index%20%28BMI%2C%20kg%5C%2Fm2%29%20and%20seem%20to%20be%20a%20consequence%20rather%20than%20cause%20of%20child%20BMI%2C%20but%20research%20so%20far%20is%20limited.%20Stability%20and%20continuity%20of%20feeding%20practices%2C%20probably%20explaining%20changes%20in%20food%20intake%20and%20child%20BMI%2C%20remain%20to%20be%20poorly%20examined.%20%282%29%20Methods%3A%20Feeding%20practices%20%28i.e.%2C%20restriction%2C%20food%20as%20reward%2C%20pressure%20to%20eat%2C%20monitoring%29%20assessed%20via%20the%20Child%20Feeding%20Questionnaire%2C%20child%20age%2C%20standardized%20BMI%20%28zBMI%29%2C%20and%20socio-economic%20status%20were%20measured%20annually%20at%20multiple%20visits%20%28range%202-8%29%20in%20a%20population-based%20longitudinal%20cohort%20study%20of%201512%20parents%20with%20their%20children%20aged%202%20to%2012%20years.%20Stability%2C%20continuity%2C%20and%20bi-directionality%20of%20feeding%20practices%20and%20child%20zBMI%20were%20calculated%20using%20correlation%20coefficients%2C%20paired%20t%20tests%2C%20and%20cross-lagged%20panels%2C%20respectively.%20%283%29%20Results%3A%20Feeding%20practices%20and%20child%20zBMI%20showed%20moderate%20to%20high%20stability.%20While%20continuity%20was%20high%20for%20restriction%2C%20minor%20temporal%20changes%20were%20observed%20for%20other%20feeding%20practices%20and%20child%20zBMI.%20Cross-lags%20indicated%20that%20child%20zBMI%20predicted%20restriction%2C%20pressure%20to%20eat%2C%20and%20monitoring%2C%20while%20food-rewarding%20predicted%20child%20zBMI%20only%20minorly.%20%284%29%20Conclusions%3A%20Parents%20seem%20to%20adapt%20feeding%20practices%20to%20child%20zBMI%20with%20the%20exception%20of%20food-rewarding.%22%2C%22date%22%3A%22Jul%2C%202019%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.3390%5C%2Fnu11081751%22%2C%22ISSN%22%3A%222072-6643%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Fnu11081751%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-07T07%3A01%3A50Z%22%7D%7D%2C%7B%22key%22%3A%22JV69ZDFD%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Eichler%20et%20al.%22%2C%22parsedDate%22%3A%222019-05%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EEichler%2C%20Janina%2C%20Ricarda%20Schmidt%2C%20Andreas%20Hiemisch%2C%20Wieland%20Kiess%2C%20and%20Anja%20Hilbert.%20%26%23x201C%3BGestational%20Weight%20Gain%2C%20Physical%20Activity%2C%20Sleep%20Problems%2C%20Substance%20Use%2C%20and%20Food%20Intake%20as%20Proximal%20Risk%20Factors%20of%20Stress%20and%20Depressive%20Symptoms%20During%20Pregnancy.%26%23x201D%3B%20%3Ci%3EBMC%20Pregnancy%20and%20Childbirth%3C%5C%2Fi%3E%2019%2C%20no.%201%20%28May%202019%29%3A%20175.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs12884-019-2328-1%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs12884-019-2328-1%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Gestational%20Weight%20Gain%2C%20Physical%20Activity%2C%20Sleep%20Problems%2C%20Substance%20Use%2C%20and%20Food%20Intake%20as%20Proximal%20Risk%20Factors%20of%20Stress%20and%20Depressive%20Symptoms%20During%20Pregnancy%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Janina%22%2C%22lastName%22%3A%22Eichler%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ricarda%22%2C%22lastName%22%3A%22Schmidt%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andreas%22%2C%22lastName%22%3A%22Hiemisch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anja%22%2C%22lastName%22%3A%22Hilbert%22%7D%5D%2C%22abstractNote%22%3A%22BACKGROUND%3A%20Because%20maternal%20depressive%20symptoms%20and%20stress%20during%20pregnancy%20are%20strongly%20associated%20with%20poor%20health%20of%20the%20mother%20and%20the%20developing%20child%2C%20understanding%20the%20predictors%20of%20women%27s%20mental%20health%20problems%20is%20important%20to%20prevent%20complications%20in%20the%20perinatal%20period.%20Therefore%2C%20this%20study%20sought%20to%20examine%20the%20association%20between%20six%20risk%20factors%20-%20gestational%20weight%20gain%20%28GWG%29%2C%20low%20physical%20activity%2C%20sleep%20problems%2C%20alcohol%20use%2C%20cigarette%20smoking%20and%20snack%20food%20intake%20-%20and%20mental%20health%20problems%20during%20pregnancy.%20We%20hypothesized%20that%20risk%20factors%20would%20predict%20mental%20health%20problems%20while%20adjusting%20for%20socio-demographic%20characteristics%20and%20pregnancy%20intention%2C%20both%20cross-sectionally%20and%20longitudinally.%5CnMETHODS%3A%20Hierarchical%20linear%20regression%20analyses%20were%20conducted%20in%20a%20population-based%20sample%20of%20N%5Cu2009%3D%5Cu2009463%20pregnant%20women%20during%20their%202nd%20trimester%20%28gestational%20age%3A%2023%20to%2028%5Cu2009weeks%29%20of%20whom%20n%5Cu2009%3D%5Cu2009349%20were%20reassessed%20during%20their%203rd%20trimester%20%28gestational%20age%3A%2033%20to%2038%5Cu2009weeks%29.%20Women%20had%20a%20mean%20age%20of%2029.8%5Cu2009%5Cu00b1%5Cu20094.2%5Cu2009years%20and%20a%20mean%20pregravid%20body%20mass%20index%20of%2023.5%5Cu2009%5Cu00b1%5Cu20094.3%5Cu2009kg%5C%2Fm2.%20Data%20were%20collected%20by%20the%20%27Leipzig%20Research%20Center%20for%20Civilization%20Diseases%27%20via%20the%20Patient%20Health%20Questionnaire%2C%20Pittsburgh%20Sleep%20Quality%20Index%2C%20Food%20Frequency%20Questionnaire%2C%20self-report%20items%20on%20physical%20activity%20and%20substance%20use%2C%20and%20objectively%20measured%20anthropometrics.%5CnRESULTS%3A%20Cross-sectionally%2C%20while%20a%20higher%20snack%20food%20intake%20and%20sleep%20problems%20predicted%20depressive%20symptoms%20and%20stress%20during%20the%202nd%20trimester%2C%20gestational%20weight%20gain%20predicted%20stress%20only.%20Longitudinally%2C%20sleep%20problems%20positively%20predicted%20depressive%20symptoms%20during%20the%203rd%20trimester.%20All%20results%20remained%20significant%20after%20controlling%20for%20age%2C%20pregravid%20body%20mass%20index%2C%20and%20pregnancy%20intention.%20GWG%20and%20significant%20longitudinal%20effects%20became%20insignificant%20when%20controlling%20for%20gestational%20age%20or%20baseline%20depressive%20symptoms%20and%20stress%2C%20respectively.%5CnCONCLUSIONS%3A%20The%20results%20showed%20that%20sleep%20problems%20were%20associated%20with%20maternal%20mental%20health%20problems%20during%20pregnancy.%20Longitudinal%20studies%20using%20standardized%20measures%2C%20particularly%20diagnostic%20interviews%20and%20physiological%20or%20biochemical%20markers%2C%20are%20warranted%20to%20confirm%20patterns%20of%20risk%20factors%2C%20their%20association%20with%20depressive%20symptoms%20and%20stress%20during%20the%20course%20of%20pregnancy%2C%20and%20their%20effects%20on%20mother%27s%20and%20child%27s%20health.%22%2C%22date%22%3A%22May%2C%202019%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1186%5C%2Fs12884-019-2328-1%22%2C%22ISSN%22%3A%221471-2393%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Forgid.org%5C%2F10.1186%5C%2Fs12884-019-2328-1%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-23T12%3A51%3A58Z%22%7D%7D%2C%7B%22key%22%3A%22D9MMZZAD%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Schmidt%20et%20al.%22%2C%22parsedDate%22%3A%222019-03%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3ESchmidt%2C%20Ricarda%2C%20Toralf%20Kirsten%2C%20Andreas%20Hiemisch%2C%20Wieland%20Kiess%2C%20and%20Anja%20Hilbert.%20%26%23x201C%3BInterview-Based%20Assessment%20of%20Avoidant%5C%2FRestrictive%20Food%20Intake%20Disorder%20%28Arfid%29%3A%20A%20Pilot%20Study%20Evaluating%20an%20Arfid%20Module%20for%20the%20Eating%20Disorder%20Examination.%26%23x201D%3B%20%3Ci%3EInternational%20Journal%20of%20Eating%20Disorders%3C%5C%2Fi%3E%2052%2C%20no.%204%20%28March%202019%29%3A%20388%26%23×2013%3B97.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1002%5C%2Feat.23063%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1002%5C%2Feat.23063%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Interview-Based%20Assessment%20of%20Avoidant%5C%2FRestrictive%20Food%20Intake%20Disorder%20%28arfid%29%3A%20A%20Pilot%20Study%20Evaluating%20an%20Arfid%20Module%20for%20the%20Eating%20Disorder%20Examination%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ricarda%22%2C%22lastName%22%3A%22Schmidt%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Toralf%22%2C%22lastName%22%3A%22Kirsten%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andreas%22%2C%22lastName%22%3A%22Hiemisch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anja%22%2C%22lastName%22%3A%22Hilbert%22%7D%5D%2C%22abstractNote%22%3A%22Objective%20Although%20avoidant%5C%2Frestrictive%20food%20intake%20disorder%20%28ARFID%29%20has%20been%20included%20as%20a%20new%20diagnostic%20entity%20of%20childhood%20feeding%20and%20eating%20disorders%2C%20there%20is%20a%20lack%20of%20measures%20to%20reliably%20and%20validly%20assess%20ARFID.%20In%20addition%2C%20virtually%20nothing%20is%20known%20about%20clinical%20characteristics%20of%20ARFID%20in%20nonclinical%20samples.%20Method%20The%20present%20study%20presents%20the%20development%20and%20validation%20of%20an%20ARFID%20module%20for%20the%20child%20and%20parent%20version%20of%20the%20Eating%20Disorder%20Examination%20%28EDE%29%20in%20a%20nonclinical%20sample%20of%20N%20%3D%2039%20children%20between%208%20and%2013%20years%20with%20underweight%20and%5C%2For%20restrictive%20eating%20behaviors.%20For%20evaluating%20the%20ARFID%20module%27s%20reliability%2C%20the%20convergence%20of%20diagnoses%20between%20two%20independent%20raters%20and%20between%20the%20child%20and%20parent%20module%20was%20determined.%20The%20module%27s%20validity%20was%20evaluated%20based%20on%20the%20full-length%20child%20version%20of%20the%20EDE%2C%20a%2024%20h%20food%20record%2C%20parent-reported%20psychosocial%20functioning%20and%20self-reported%20quality%20of%20life%2C%20and%20objective%20anthropometric%20measures.%20Results%20In%20total%2C%20n%20%3D%207%20children%20received%20an%20ARFID%20diagnosis.%20The%20ARFID%20module%20showed%20high%20interrater%20reliability%2C%20especially%20for%20the%20parent%20version%2C%20and%20high%20convergence%20between%20child%20and%20parent%20report.%20Evidence%20for%20the%20module%27s%20convergent%2C%20divergent%2C%20and%20discriminant%20validity%20was%20provided.%20Specifically%2C%20children%20with%20versus%20without%20ARFID%20reported%20significantly%20less%20macro-%20and%20micronutrient%20intake%20and%20were%20more%20likely%20to%20be%20underweight.%20Discussion%20This%20pilot%20study%20indicates%20the%20child%20and%20parent%20version%20of%20the%20EDE%20ARFID%20module%20to%20be%20promising%20for%20diagnosing%20ARFID%20in%20a%20structured%20way%20but%20still%20necessitates%20a%20validation%20in%20a%20larger%20clinical%20and%20community-based%20sample.%22%2C%22date%22%3A%22March%202019%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1002%5C%2Feat.23063%22%2C%22ISSN%22%3A%221098-108X%22%2C%22url%22%3A%22http%3A%5C%2F%5C%2Fonlinelibrary.wiley.com%5C%2Fdoi%5C%2Fabs%5C%2F10.1002%5C%2Feat.23063%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-07T07%3A01%3A25Z%22%7D%7D%2C%7B%22key%22%3A%22U2UY5899%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Poulain%20et%20al.%22%2C%22parsedDate%22%3A%222018-12%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EPoulain%2C%20Tanja%2C%20Ulrike%20Spielau%2C%20Mandy%20Vogel%2C%20Antje%20K%26%23xF6%3Brner%2C%20and%20Wieland%20Kiess.%20%26%23x201C%3BCocu%3A%20A%20New%20Short%20Questionnaire%20to%20Evaluate%20Diet%20Composition%20and%20Culture%20of%20Eating%20in%20Children%20and%20Adolescents.%26%23x201D%3B%20%3Ci%3EClinical%20Nutrition%20%28Edinburgh%2C%20Scotland%29%3C%5C%2Fi%3E%2038%2C%20no.%206%20%28December%202018%29%3A%202858%26%23×2013%3B65.%20%3Ca%20class%3D%27zp-ItemURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.clnu.2018.12.020%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.clnu.2018.12.020%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Cocu%3A%20A%20New%20Short%20Questionnaire%20to%20Evaluate%20Diet%20Composition%20and%20Culture%20of%20Eating%20in%20Children%20and%20Adolescents%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ulrike%22%2C%22lastName%22%3A%22Spielau%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%5D%2C%22abstractNote%22%3A%22BACKGROUND%20%26%20AIMS%3A%20The%20aim%20of%20this%20project%20was%20to%20develop%20and%20validate%20a%20short%20questionnaire%20%28titled%20CoCu%20-%20Composition%20and%20Culture%20of%20Eating%29%20for%20assessing%20the%20composition%20of%20the%20diets%20of%20children%20and%20adolescents%2C%20and%20their%20culture%20of%20eating.%20We%20also%20investigated%20whether%20what%20and%20how%20children%20eat%20is%20associated%20with%20their%20age%2C%20gender%2C%20and%20social%20background.%5CnMETHODS%3A%20The%20%5C%22diet%20composition%5C%22%20part%20of%20the%20developed%20questionnaire%20contains%2014%20questions%20about%20the%20number%20of%20portions%20of%20different%20food%20products%20the%20subject%20child%20eats%20per%20week%20or%20per%20day.%20The%20selection%20of%20food%20products%20was%20based%20on%20food%20groups%20assessed%20in%20a%20Food%20Frequency%20Questionnaire%20%28FFQ%29.%20The%20%5C%22culture%20of%20eating%5C%22%20part%20asks%20five%20questions%20about%20how%20children%20eat%20%28e.g.%2C%20number%20of%20meals%2C%20frequency%20of%20shared%20dinners%29.%20A%20total%20of%201604%20questionnaires%20were%20completed%20within%20the%20framework%20of%20the%20LIFE%20Child%20study%20in%20Leipzig%2C%20Germany%2C%20with%20741%20questionnaires%20regarding%20a%20child%20aged%20between%2010%20and%2019%20%28self%20reporting%29%20and%20863%20regarding%20a%20child%20aged%20between%202%20and%209%20%28parent%20reporting%29.%20In%20a%20subsample%20%28n%5Cu00a0%3D%5Cu00a0212%20for%20the%20parent-report%20group%20and%20188%20for%20the%20self-report%20group%29%2C%20retest%20reliability%20was%20assessed%20by%20correlating%20answers%20given%20at%20two%20consecutive%20study%20visits%20%28one%20year%20apart%29.%20In%20another%20subsample%20of%20the%20self-report%20group%20%28n%5Cu00a0%3D%5Cu00a0105%29%2C%20the%20validity%20of%20the%20questionnaire%20was%20assessed%20by%20comparing%20answers%20in%20CoCu%20with%20answers%20in%20the%20FFQ.%20Multiple%20regression%20analysis%20was%20used%20to%20assess%20whether%20aspects%20of%20diet%20composition%20and%20the%20culture%20of%20eating%20were%20associated%20with%20child%20age%2C%20gender%2C%20and%20social%20background.%5CnRESULTS%3A%20The%20analyses%20revealed%20significant%20positive%20correlations%20between%20responses%20given%20at%20two%20consecutive%20study%20visits%20as%20well%20as%20significant%20positive%20correlations%20between%20the%20CoCu%20data%20and%20the%20FFQ.%20Furthermore%2C%20both%20the%20composition%20of%20the%20children%27s%20diets%20and%20their%20eating%20culture%20were%20found%20to%20vary%20significantly%20depending%20on%20child%20age%2C%20gender%2C%20and%20social%20background.%5CnCONCLUSIONS%3A%20The%20proposed%20short%20nutrition%20questionnaire%20represents%20a%20useful%2C%20inexpensive%2C%20and%20time-efficient%20tool%20for%20surveying%20the%20diets%20of%20children%20and%20adolescents.%22%2C%22date%22%3A%22Dec%2C%202018%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1016%5C%2Fj.clnu.2018.12.020%22%2C%22ISSN%22%3A%221532-1983%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.clnu.2018.12.020%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-07T07%3A01%3A32Z%22%7D%7D%2C%7B%22key%22%3A%223MFGR39Q%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Hartmann%20et%20al.%22%2C%22parsedDate%22%3A%222018-11%22%2C%22numChildren%22%3A2%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EHartmann%2C%20Andrea%20S.%2C%20Tanja%20Poulain%2C%20Mandy%20Vogel%2C%20Andreas%20Hiemisch%2C%20Wieland%20Kiess%2C%20and%20Anja%20Hilbert.%20%26%23x201C%3BCorrection%20to%3A%20Prevalence%20of%20Pica%20and%20Rumination%20Behaviors%20in%20German%20Children%20Aged%207-14%20and%20Their%20Associations%20with%20Feeding%2C%20Eating%2C%20and%20General%20Psychopathology%3A%20A%20Population-Based%20Study.%26%23x201D%3B%20%3Ci%3EEuropean%20Child%20%26amp%3B%20Adolescent%20Psychiatry%3C%5C%2Fi%3E%2027%2C%20no.%2011%20%28November%202018%29%3A%201509.%20https%3A%5C%2F%5C%2Fdoi.org%5C%2F%3Ca%20class%3D%27zp-ItemURL%27%20target%3D%27_blank%27%20href%3D%2710.1007%5C%2Fs00787-018-1179-z%27%3E10.1007%5C%2Fs00787-018-1179-z%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Correction%20to%3A%20Prevalence%20of%20Pica%20and%20Rumination%20Behaviors%20in%20German%20Children%20Aged%207-14%20and%20Their%20Associations%20with%20Feeding%2C%20Eating%2C%20and%20General%20Psychopathology%3A%20A%20Population-Based%20Study%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andrea%20S.%22%2C%22lastName%22%3A%22Hartmann%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andreas%22%2C%22lastName%22%3A%22Hiemisch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anja%22%2C%22lastName%22%3A%22Hilbert%22%7D%5D%2C%22abstractNote%22%3A%22n%20the%20original%20publication%2C%20under%20the%20discussion%20section.%22%2C%22date%22%3A%222018-11%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1007%5C%2Fs00787-018-1179-z%22%2C%22ISSN%22%3A%221435-165X%22%2C%22url%22%3A%2210.1007%5C%2Fs00787-018-1179-z%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-27T08%3A23%3A06Z%22%7D%7D%2C%7B%22key%22%3A%22YULVGQEH%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22H%5Cu00e4ndel%20et%20al.%22%2C%22parsedDate%22%3A%222018-10%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EH%26%23xE4%3Bndel%2C%20Norman%2C%20Thomas%20Mothes%2C%20David%20Petroff%2C%20Ronny%20Baber%2C%20Anne%20Jurkutat%2C%20Gunter%20Flemming%2C%20Wieland%20Kiess%2C%20et%20al.%20%26%23x201C%3BWill%20the%20Real%20Coeliac%20Disease%20Please%20Stand%20Up%3F%20Coeliac%20Disease%20Prevalence%20in%20the%20German%20LIFE%20Child%20Study.%26%23x201D%3B%20%3Ci%3EJournal%20of%20Pediatric%20Gastroenterology%20and%20Nutrition%3C%5C%2Fi%3E%2067%2C%20no.%204%20%28October%202018%29%3A%20494.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1097%5C%2FMPG.0000000000002052%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1097%5C%2FMPG.0000000000002052%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Will%20the%20Real%20Coeliac%20Disease%20Please%20Stand%20Up%3F%20Coeliac%20Disease%20Prevalence%20in%20the%20German%20LIFE%20Child%20Study%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Norman%22%2C%22lastName%22%3A%22H%5Cu00e4ndel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Thomas%22%2C%22lastName%22%3A%22Mothes%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22David%22%2C%22lastName%22%3A%22Petroff%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ronny%22%2C%22lastName%22%3A%22Baber%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anne%22%2C%22lastName%22%3A%22Jurkutat%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Gunter%22%2C%22lastName%22%3A%22Flemming%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andreas%22%2C%22lastName%22%3A%22Hiemisch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wolfgang%22%2C%22lastName%22%3A%22Schlumberger%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Joachim%22%2C%22lastName%22%3A%22Thiery%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Johannes%22%2C%22lastName%22%3A%22Wolf%22%7D%5D%2C%22abstractNote%22%3A%22Objectives%3A%5Cu00a0Assessing%20the%20seroprevalence%20and%20the%20prevalence%20of%20definite%20coeliac%20disease%20%28CD%29%20in%20the%20German%20LIFE%20Child%20Health%20study%20cohort%20including%20immunoglobulin%20A%20%28IgA%29%20antibodies%20against%20tissue%20transglutaminase%20%28IgA-TTG%29%20in%20addition%20to%20IgG%20antibodies%20against%20deamidated%20gliadin%20peptides%20%28IgG-DGP%29%20and%20human%20leukocyte%20antigen%20%28HLA%29-DQ2%5C%2F8%20genotyping.%5CnMethods%3A%5Cu00a0Samples%20from%20children%20and%20adolescents%20were%20first%20screened%20for%20IgA-TTG%20and%20IgG-DGP.%20If%20IgA-TTG%20was%20above%200.5%20times%20the%20upper%20limit%20of%20normal%20and%5C%2For%20IgG-DGP%20was%20positive%2C%20IgA%20antibodies%20against%20endomysium%20%28IgA-EmA%29%20were%20measured%2C%20and%20HLA%20was%20genotyped.%20In%20patients%20with%20only%20IgG-DGP%20positivity%2C%20total%20IgA%20was%20assayed.%20Subjects%20with%20suspicious%20results%20were%20followed%20up%20serologically%20and%2C%20in%20case%20of%20repeatedly%20positive%20antibody%20results%2C%20invited%20for%20a%20personal%20interview.%20Further%20diagnostic%20data%20were%20obtained%20independent%20from%20our%20study.%5CnResults%3A%5Cu00a0We%20screened%202363%20children%27s%20blood%20samples%20collected%20from%202011%20to%202015.%20The%20seroprevalence%2C%20that%20is%2C%20IgA-TTG%20and%5C%2For%20IgA-EmA%20positivity%20or%20IgG-DGP%20positivity%20with%20IgA%20%3C0.05%20g%5C%2FL%2C%20was%201.57%25%20%2895%25%20confidence%20interval%20%5BCI95%25%5D%201.14%5Cu20132.15%29.%20The%20prevalence%20of%20suspected%20CD%2C%20that%20is%2C%20seroprevalence%20and%20compatible%20HLA%20genotype%20with%20hitherto%20unknown%20mucosal%20damage%2C%20was%201.35%25%20%28CI95%25%200.96%5Cu20131.91%29.%20Definite%20CD%2C%20that%20is%2C%20seropositivity%20accompanied%20by%20positive%20intestinal%20biopsy%20or%20IgA-TTG%20%5Cu2265%2010%20%5Cu00d7%20upper%20limit%20of%20normal%2C%20was%20found%20in%200.42%25%20%28CI95%25%200.22%5Cu20130.80%29.%20Seven%20children%20claimed%20to%20have%20CD.%20The%20HLA%20haplotype%2C%20however%2C%20matched%20in%20only%204%20of%20them%20resulting%20in%20an%20overall%20CD%20prevalence%20of%20at%20least%200.59%25%20%28CI95%25%200.34%5Cu20131.02%29.%20Thirteen%20unclear%20cases%20remained%3B%20therefore%2C%20the%20prevalence%20may%20even%20be%20higher.%5CnConclusions%3A%5Cu00a0The%20prevalence%20of%20definite%20CD%20in%20a%20population-representative%20German%20cohort%20is%20higher%20than%20previously%20described.%20HLA-DQ%20typing%20is%20helpful%20to%20identify%20false-positive%20IgA-TTG%20patients%20negative%20for%20IgA-EmA%20and%5C%2For%20IgG-DGP%20under%20screening%20conditions%20and%20unmasks%20possible%20misdiagnoses%20of%20CD.%22%2C%22date%22%3A%22October%202018%22%2C%22language%22%3A%22en-US%22%2C%22DOI%22%3A%2210.1097%5C%2FMPG.0000000000002052%22%2C%22ISSN%22%3A%220277-2116%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fjournals.lww.com%5C%2Fjpgn%5C%2FFulltext%5C%2F2018%5C%2F10000%5C%2FWill_the_Real_Coeliac_Disease_Please_Stand_Up_.15.aspx%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-24T08%3A28%3A14Z%22%7D%7D%2C%7B%22key%22%3A%22MS9B2STR%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Schmidt%20et%20al.%22%2C%22parsedDate%22%3A%222018-08%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3ESchmidt%2C%20Ricarda%2C%20Mandy%20Vogel%2C%20Andreas%20Hiemisch%2C%20Wieland%20Kiess%2C%20and%20Anja%20Hilbert.%20%26%23x201C%3BPathological%20and%20Non-Pathological%20Variants%20of%20Restrictive%20Eating%20Behaviors%20in%20Middle%20Childhood%3A%20A%20Latent%20Class%20Analysis.%26%23x201D%3B%20%3Ci%3EAppetite%3C%5C%2Fi%3E%20127%20%28August%202018%29%3A%20257%26%23×2013%3B65.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.appet.2018.04.030%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.appet.2018.04.030%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Pathological%20and%20Non-Pathological%20Variants%20of%20Restrictive%20Eating%20Behaviors%20in%20Middle%20Childhood%3A%20A%20Latent%20Class%20Analysis%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ricarda%22%2C%22lastName%22%3A%22Schmidt%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andreas%22%2C%22lastName%22%3A%22Hiemisch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anja%22%2C%22lastName%22%3A%22Hilbert%22%7D%5D%2C%22abstractNote%22%3A%22Although%20restrictive%20eating%20behaviors%20are%20very%20common%20during%20early%20childhood%2C%20their%20precise%20nature%20and%20clinical%20correlates%20remain%20unclear.%20Especially%2C%20there%20is%20little%20evidence%20on%20restrictive%20eating%20behaviors%20in%20older%20children%20and%20their%20associations%20with%20children%27s%20shape%20concern.%20The%20present%20population-based%20study%20sought%20to%20delineate%20subgroups%20of%20restrictive%20eating%20patterns%20in%20N%5Cu202f%3D%5Cu202f799%207-14%20year%20old%20children.%20Using%20Latent%20Class%20Analysis%2C%20children%20were%20classified%20based%20on%20six%20restrictive%20eating%20behaviors%20%28for%20example%2C%20picky%20eating%2C%20food%20neophobia%2C%20and%20eating-related%20anxiety%29%20and%20shape%20concern%2C%20separately%20in%20three%20age%20groups.%20For%20cluster%20validation%2C%20sociodemographic%20and%20objective%20anthropometric%20data%2C%20parental%20feeding%20practices%2C%20and%20general%20and%20eating%20disorder%20psychopathology%20were%20used.%20The%20results%20showed%20a%203-cluster%20solution%20across%20all%20age%20groups%3A%20an%20asymptomatic%20class%20%28Cluster%201%29%2C%20a%20class%20with%20restrictive%20eating%20behaviors%20without%20shape%20concern%20%28Cluster%202%29%2C%20and%20a%20class%20showing%20restrictive%20eating%20behaviors%20with%20prominent%20shape%20concern%20%28Cluster%203%29.%20The%20clusters%20differed%20in%20all%20variables%20used%20for%20validation.%20Particularly%2C%20the%20proportion%20of%20children%20with%20symptoms%20of%20avoidant%5C%2Frestrictive%20food%20intake%20disorder%20was%20greater%20in%20Cluster%202%20than%20Clusters%201%20and%203.%20The%20study%20underlined%20the%20importance%20of%20considering%20shape%20concern%20to%20distinguish%20between%20different%20phenotypes%20of%20children%27s%20restrictive%20eating%20patterns.%20Longitudinal%20data%20are%20needed%20to%20evaluate%20the%20clusters%27%20predictive%20effects%20on%20children%27s%20growth%20and%20development%20of%20clinical%20eating%20disorders.%22%2C%22date%22%3A%22August%2C%202018%22%2C%22language%22%3A%22%22%2C%22DOI%22%3A%2210.1016%5C%2Fj.appet.2018.04.030%22%2C%22ISSN%22%3A%220195-6663%22%2C%22url%22%3A%22http%3A%5C%2F%5C%2Fwww.sciencedirect.com%5C%2Fscience%5C%2Farticle%5C%2Fpii%5C%2FS0195666317310954%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-07T07%3A01%3A25Z%22%7D%7D%2C%7B%22key%22%3A%22TUMWT87K%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Hartmann%20et%20al.%22%2C%22parsedDate%22%3A%222018-04%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EHartmann%2C%20Andrea%20S.%2C%20Tanja%20Poulain%2C%20Mandy%20Vogel%2C%20Andreas%20Hiemisch%2C%20Wieland%20Kiess%2C%20and%20Anja%20Hilbert.%20%26%23x201C%3BPrevalence%20of%20Pica%20and%20Rumination%20Behaviors%20in%20German%20Children%20Aged%207-14%20and%20Their%20Associations%20with%20Feeding%2C%20Eating%2C%20and%20General%20Psychopathology%3A%20A%20Population-Based%20Study.%26%23x201D%3B%20%3Ci%3EEuropean%20Child%20%26amp%3B%20Adolescent%20Psychiatry%3C%5C%2Fi%3E%2027%2C%20no.%2011%20%28April%202018%29%3A%201499%26%23×2013%3B1508.%20https%3A%5C%2F%5C%2Fdoi.org%5C%2F%3Ca%20class%3D%27zp-ItemURL%27%20target%3D%27_blank%27%20href%3D%2710.1007%5C%2Fs00787-018-1153-9%27%3E10.1007%5C%2Fs00787-018-1153-9%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Prevalence%20of%20Pica%20and%20Rumination%20Behaviors%20in%20German%20Children%20Aged%207-14%20and%20Their%20Associations%20with%20Feeding%2C%20Eating%2C%20and%20General%20Psychopathology%3A%20A%20Population-Based%20Study%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andrea%20S.%22%2C%22lastName%22%3A%22Hartmann%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andreas%22%2C%22lastName%22%3A%22Hiemisch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anja%22%2C%22lastName%22%3A%22Hilbert%22%7D%5D%2C%22abstractNote%22%3A%22Despite%20potentially%20severe%20medical%20consequences%20of%20pica%20and%20rumination%20disorder%20%28RD%29%2C%20little%20is%20known%20about%20their%20prevalence%20and%20association%20with%20other%20psychopathology%20in%20childhood.%20As%20a%20part%20of%20a%20larger%20population-based%20study%2C%20804%20children%20aged%207-14%5Cu00a0years%20and%20their%20parents%20were%20asked%20about%20their%20experience%20of%20pica%20and%20RD%20behaviors%2C%20and%20associated%20eating%2C%20feeding%20and%20general%20psychopathology.%20A%20total%20of%2012.31%20and%2011.49%25%20of%20the%20participants%20reported%20having%20engaged%20in%20pica%20or%20RD%20behaviors%2C%20respectively%2C%20at%20least%20once.%20Recurring%20pica%20or%20RD%20behaviors%20had%20been%20experienced%20by%204.98%20and%201.49%25%20of%20the%20participants%2C%20respectively.%20The%20behaviors%20showed%20a%20significant%20but%20small%20correlation%20with%20one%20another%20%28r%5Cu2009%3D%5Cu20090.28%2C%20p%5Cu2009%3C%5Cu20090.01%29.%20Correlations%20with%20symptoms%20of%20avoidant%5C%2Frestrictive%20food%20intake%20disorder%20%28ARFID%29%20were%20significant%20but%20small%20%28pica%3A%20r%5Cu2009%3D%5Cu20090.18%2C%20RD%3A%20r%5Cu2009%3D%5Cu20090.27%2C%20both%20p%5Cu2009%3C%5Cu20090.01%29.%20Prevalence%20rates%20of%20recurring%20pica%20behavior%20were%20significantly%20increased%20if%20recurring%20RD%20was%20present%20%2858.33%25%29%2C%20and%20also%20vice%20versa%20%2817.50%25%29.%20The%20prevalence%20rates%20of%20recurrent%20pica%20and%20RD%20behaviors%20were%20also%20increased%20in%20the%20presence%20of%20an%20ARFID%20diagnosis%20%28both%20behaviors%2012.0%25%29.%20However%2C%20correlations%20with%20restraint%20and%20eating%2C%20weight%2C%20and%20shape%20concern%20were%20non-significant%20%28all%20p%5Cu2009%3E%5Cu20090.05%29.%20Additionally%2C%20RD%20behavior%20was%20positively%20correlated%20with%20emotional%20and%20conduct%20problems%20%28r%5Cu2009%3D%5Cu20090.15%20and%200.22%2C%20both%20p%5Cu2009%3C%5Cu20090.01%29%2C%20and%20both%20behaviors%20were%20negatively%20correlated%20with%20prosocial%20behavior%20%28r%5Cu2009%3D%5Cu2009-%5Cu00a0%5Cu20090.10%20and%20-%5Cu00a00.09%2C%20both%20p%5Cu2009%3C%5Cu20090.05%29.%20Our%20findings%20underscore%20the%20clinical%20significance%20of%20pica%20and%20RD%20behaviors.%20More%20research%20is%20warranted%20on%20both%20disorders%20and%20their%20association%20and%20relation%20with%20ARFID%20to%20deepen%20the%20understanding%20of%20their%20presentation%20and%20to%20ascertain%20diagnostic%20validity.%22%2C%22date%22%3A%22Apr%2C%202018%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1007%5C%2Fs00787-018-1153-9%22%2C%22ISSN%22%3A%221435-165X%22%2C%22url%22%3A%2210.1007%5C%2Fs00787-018-1153-9%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-07T07%3A01%3A46Z%22%7D%7D%2C%7B%22key%22%3A%22IFVDA26R%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Kliem%20et%20al.%22%2C%22parsedDate%22%3A%222017-06%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EKliem%2C%20S%26%23xF6%3Bren%2C%20Ricarda%20Schmidt%2C%20Mandy%20Vogel%2C%20Andreas%20Hiemisch%2C%20Wieland%20Kiess%2C%20and%20Anja%20Hilbert.%20%26%23x201C%3BAn%208-Item%20Short%20Form%20of%20the%20Eating%20Disorder%20Examination-Questionnaire%20Adapted%20for%20Children%20%28ChEDE-Q8%29.%26%23x201D%3B%20%3Ci%3EInternational%20Journal%20of%20Eating%20Disorders%3C%5C%2Fi%3E%2050%2C%20no.%206%20%28June%202017%29%3A%20679%26%23×2013%3B86.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1002%5C%2Feat.22658%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1002%5C%2Feat.22658%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22An%208-item%20short%20form%20of%20the%20Eating%20Disorder%20Examination-Questionnaire%20adapted%20for%20children%20%28ChEDE-Q8%29%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22S%5Cu00f6ren%22%2C%22lastName%22%3A%22Kliem%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ricarda%22%2C%22lastName%22%3A%22Schmidt%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andreas%22%2C%22lastName%22%3A%22Hiemisch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anja%22%2C%22lastName%22%3A%22Hilbert%22%7D%5D%2C%22abstractNote%22%3A%22Eating%20disturbances%20are%20common%20in%20children%20placing%20a%20vulnerable%20group%20of%20them%20at%20risk%20for%20full-syndrome%20eating%20disorders%20and%20adverse%20health%20outcomes.%20To%20provide%20a%20valid%20self-report%20assessment%20of%20eating%20disorder%20psychopathology%20in%20children%2C%20a%20short%20form%20of%20the%20child%20version%20of%20the%20Eating%20Disorder%20Examination%20%28ChEDE-Q%29%20was%20psychometrically%20evaluated.%20Similar%20to%20the%20EDE-Q%2C%20the%20ChEDE-Q%20provides%20assessment%20of%20eating%20disorder%20psychopathology%20related%20to%20anorexia%20nervosa%2C%20bulimia%20nervosa%2C%20and%20binge-eating%20disorder%3B%20however%2C%20the%20ChEDE-Q%20does%20not%20assess%20symptoms%20of%20avoidant%5C%2Frestrictive%20food%20intake%20disorder%2C%20pica%2C%20or%20rumination%20disorder.%20In%201%2C836%20participants%20ages%207%20to%2018%20years%2C%20recruited%20from%20two%20independent%20population-based%20samples%2C%20the%20factor%20structure%20of%20the%20recently%20established%208-item%20short%20form%20EDE-Q8%20for%20adults%20was%20examined%2C%20including%20measurement%20invariance%20analyses%20on%20age%2C%20gender%2C%20and%20weight%20status%20derived%20from%20objectively%20measured%20weight%20and%20height.%20For%20convergent%20validity%2C%20the%20ChEDE-Q%20global%20score%2C%20body%20esteem%20scale%2C%20strengths%20and%20difficulties%20questionnaire%2C%20and%20sociodemographic%20characteristics%20were%20used.%20Item%20characteristics%20and%20age-%20and%20gender-specific%20norms%20were%20calculated.%20Confirmatory%20factor%20analysis%20revealed%20good%20model%20fit%20for%20the%208-item%20ChEDE-Q.%20Measurement%20invariance%20analyses%20indicated%20strict%20invariance%20for%20all%20analyzed%20subgroups.%20Convergent%20validity%20was%20provided%20through%20associations%20with%20well-established%20questionnaires%20and%20age%2C%20gender%2C%20and%20weight%20status%2C%20in%20expected%20directions.%20The%20newly%20developed%20ChEDE-Q8%20proved%20to%20be%20a%20psychometrically%20sound%20and%20economical%20self-report%20assessment%20tool%20of%20eating%20disorder%20psychopathology%20in%20children.%20Further%20validation%20studies%20are%20needed%2C%20particularly%20concerning%20discriminant%20and%20predictive%20validity.%22%2C%22date%22%3A%22June%2C%202017%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1002%5C%2Feat.22658%22%2C%22ISSN%22%3A%221098-108X%22%2C%22url%22%3A%22http%3A%5C%2F%5C%2Fonlinelibrary.wiley.com%5C%2Fdoi%5C%2F10.1002%5C%2Feat.22658%5C%2Fabstract%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-07T07%3A01%3A41Z%22%7D%7D%2C%7B%22key%22%3A%226I7EFLG4%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Schmidt%20et%20al.%22%2C%22parsedDate%22%3A%222017-02%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3ESchmidt%2C%20Ricarda%2C%20Robert%20Richter%2C%20Anne%20Brauhardt%2C%20Andreas%20Hiemisch%2C%20Wieland%20Kiess%2C%20and%20Anja%20Hilbert.%20%26%23x201C%3BParental%20Feeding%20Practices%20in%20Families%20with%20Children%20Aged%202%26%23×2013%3B13%20Years%3A%20Psychometric%20Properties%20and%20Child%20Age-Specific%20Norms%20of%20the%20German%20Version%20of%20the%20Child%20Feeding%20Questionnaire%20%28Cfq%29.%26%23x201D%3B%20%3Ci%3EAppetite%3C%5C%2Fi%3E%20109%20%28February%202017%29%3A%20154%26%23×2013%3B64.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.appet.2016.11.038%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.appet.2016.11.038%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Parental%20Feeding%20Practices%20in%20Families%20with%20Children%20Aged%202%5Cu201313%20Years%3A%20Psychometric%20Properties%20and%20Child%20Age-Specific%20Norms%20of%20the%20German%20Version%20of%20the%20Child%20Feeding%20Questionnaire%20%28cfq%29%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ricarda%22%2C%22lastName%22%3A%22Schmidt%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Robert%22%2C%22lastName%22%3A%22Richter%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anne%22%2C%22lastName%22%3A%22Brauhardt%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andreas%22%2C%22lastName%22%3A%22Hiemisch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anja%22%2C%22lastName%22%3A%22Hilbert%22%7D%5D%2C%22abstractNote%22%3A%22The%20Child%20Feeding%20Questionnaire%20%28CFQ%29%20is%20a%20self-report%20questionnaire%20for%20assessing%20parental%20attitudes%20to%20child%20weight%20and%20parental%20feeding%20practices.%20Previous%20evaluations%20of%20its%20psychometric%20properties%20were%20conducted%20primarily%20with%20small%20to%20medium-sized%20samples%20%28N%5Cu00a0%3C%5Cu00a0500%29%20and%20a%20small%20range%20of%20children%27s%20age.%20The%20present%20study%20aims%20to%20analyze%20the%20psychometric%20properties%20of%20the%20CFQ%20in%20a%20large%20German%20community%20sample%20and%2C%20for%20the%20first%20time%2C%20to%20establish%20normative%20data.%20Within%20the%20population-based%20LIFE%20Child%20study%2C%20the%20CFQ%20was%20administered%20to%20N%5Cu00a0%3D%5Cu00a0982%20mothers%20of%202-%20to%2013-year-old%20children.%20Psychometric%20analyses%20on%20item%20statistics%20and%20internal%20consistency%20were%20conducted.%20Using%20structural%20equation%20modeling%2C%20four%20empirically-based%20factorial%20models%20of%20the%20CFQ%20were%20evaluated%2C%20and%20measurement%20invariance%20across%20child%20age%20groups%20and%20sex%20was%20examined.%20Age-specific%20norms%20for%20the%20CFQ%20subscales%20were%20computed.%20Item%20statistics%20were%20highly%20favorable%20for%20the%20majority%20of%20items%2C%20but%20floor%20and%20ceiling%20effects%20were%20found%20for%2014%20of%2031%20items.%20Internal%20consistency%20of%20the%20CFQ%20subscales%20ranged%20from%20acceptable%20to%20excellent%20%280.71%5Cu00a0%5Cu2264%5Cu00a0%5Cu03b1%5Cu00a0%5Cu2264%5Cu00a00.91%29%2C%20except%20for%20the%20subscale%20Perceived%20Responsibility%20%28%5Cu03b1%5Cu00a0%3D%5Cu00a00.65%29.%20Regarding%20factorial%20validity%2C%20an%20eight-factor%20model%20with%20the%20newly%20created%20Reward%20subscale%20provided%20the%20best%20fit%20to%20the%20data.%20This%20model%20was%20factorial%20invariant%20across%20child%20sex%20and%20adjacent%20age%20groups.%20Maternal%20and%20child%20weight%20status%20showed%20large%20effects%20on%20CFQ%20subscale%20scores.%20The%20analyses%20established%20good%20psychometric%20properties%20for%20the%20German%20version%20of%20the%20CFQ%20and%20confirmed%20an%20eight-factor%20model.%20The%20provided%20norms%20allow%20for%20the%20comparison%20of%20individual%20parental%20feeding%20practices%20and%20change%20over%20time.%20The%20CFQ%27s%20sensitivity%20to%20change%20and%20longitudinal%20associations%20of%20parental%20feeding%20practices%20and%20child%20weight%20status%20warrant%20further%20research.%22%2C%22date%22%3A%22February%2C%202017%22%2C%22language%22%3A%22%22%2C%22DOI%22%3A%2210.1016%5C%2Fj.appet.2016.11.038%22%2C%22ISSN%22%3A%220195-6663%22%2C%22url%22%3A%22http%3A%5C%2F%5C%2Fwww.sciencedirect.com%5C%2Fscience%5C%2Farticle%5C%2Fpii%5C%2FS0195666316308583%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-24T11%3A25%3A41Z%22%7D%7D%2C%7B%22key%22%3A%22D36JFJIJ%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Sonnengr%5Cu00fcn%20et%20al.%22%2C%22parsedDate%22%3A%222016-06%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3ESonnengr%26%23xFC%3Bn%2C%20Lilli%2C%20Celestina%20Schober%2C%20Mandy%20Vogel%2C%20Andreas%20Hiemisch%2C%20Mirko%20D%26%23xF6%3Bhnert%2C%20Anja%20Hilbert%2C%20and%20Wieland%20Kiess.%20%26%23x201C%3BFeeding%2C%20Eating%20and%20Behavioral%20Disturbances%20in%20Prader-Willi%20Syndrome%20and%20Non-Syndromal%20Obesity.%26%23x201D%3B%20%3Ci%3EJournal%20of%20Pediatric%20Endocrinology%20and%20Metabolism%3C%5C%2Fi%3E%2029%2C%20no.%208%20%28June%202016%29%3A%20923%26%23×2013%3B32.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1515%5C%2Fjpem-2016-0085%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1515%5C%2Fjpem-2016-0085%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Feeding%2C%20Eating%20and%20Behavioral%20Disturbances%20in%20Prader-Willi%20Syndrome%20and%20Non-Syndromal%20Obesity%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Lilli%22%2C%22lastName%22%3A%22Sonnengr%5Cu00fcn%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Celestina%22%2C%22lastName%22%3A%22Schober%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andreas%22%2C%22lastName%22%3A%22Hiemisch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mirko%22%2C%22lastName%22%3A%22D%5Cu00f6hnert%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anja%22%2C%22lastName%22%3A%22Hilbert%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%5D%2C%22abstractNote%22%3A%22Background%3A%5Cn%5CnAlthough%20most%20individuals%20with%20Prader-Willi%20syndrome%20%28PWS%29%20are%20obese%2C%20little%20is%20known%20about%20the%20impact%20of%20obesity-related%20psychosocial%20factors%20in%20PWS.%20In%20the%20present%20study%20we%20compared%20feeding%2C%20eating%2C%20and%20behavioral%20disturbances%20in%20children%20and%20adolescents%20with%20PWS%2C%20peers%20with%20non-syndromal%20obesity%2C%20and%20normal%20weight%20controls.%5CnMethods%3A%5Cn%5CnTwelve%20persons%20with%20PWS%2C%20aged%207%5Cu201322%20years%2C%20age-%20and%20gender-matched%20obese%20and%20normal%20weight%20individuals%20were%20analyzed%20regarding%20parental%20feeding%20practices%2C%20eating%20disturbances%2C%20and%20behavioral%20problems%20via%20standardized%20questionnaires.%5CnResults%3A%5Cn%5CnParents%20of%20individuals%20with%20PWS%20reported%20significantly%20more%20restrictive%20feeding%20and%20monitoring%20than%20did%20parents%20of%20obese%20or%20normal%20weight%20children%20without%20PWS%20%28p%3C0.05%29.%20Social%20problems%20were%20more%20common%20in%20the%20obese%20and%20the%20PWS%20group%20than%20in%20the%20normal-weight%20group%20%28p%3C0.05%29.%20Behavioral%20problems%20were%20significantly%20correlated%20with%20parental%20restrictive%20feeding%20practices.%5CnConclusions%3A%5Cn%5CnOur%20data%20show%20that%20children%20and%20adolescents%20with%20PWS%20are%20affected%20by%20psychosocial%20problems%2C%20and%20that%20restrictive%20feeding%20practices%20might%20be%20associated%20with%20more%20severe%20behavioral%20problems.%20Further%20studies%20in%20larger%20samples%20will%20be%20necessary%20to%20replicate%20these%20results%20and%20possibly%20provide%20new%20therapeutic%20approaches%20for%20the%20management%20of%20PWS.%22%2C%22date%22%3A%222016-06%22%2C%22language%22%3A%22%22%2C%22DOI%22%3A%2210.1515%5C%2Fjpem-2016-0085%22%2C%22ISSN%22%3A%220334-018X%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.degruyter.com%5C%2Fview%5C%2Fj%5C%2Fjpem.2016.29.issue-8%5C%2Fjpem-2016-0085%5C%2Fjpem-2016-0085.xml%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-24T13%3A13%3A32Z%22%7D%7D%2C%7B%22key%22%3A%22S5ZBNIFX%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Penke%20et%20al.%22%2C%22parsedDate%22%3A%222015-09-05%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EPenke%2C%20Melanie%2C%20Per%20S.%20Larsen%2C%20Susanne%20Schuster%2C%20Morten%20Dall%2C%20Benjamin%20A.%20H.%20Jensen%2C%20Theresa%20Gorski%2C%20Andrej%20Meusel%2C%20et%20al.%20%26%23x201C%3BHepatic%20Nad%20Salvage%20Pathway%20Is%20Enhanced%20in%20Mice%20on%20a%20High-Fat%20Diet.%26%23x201D%3B%20%3Ci%3EMolecular%20and%20Cellular%20Endocrinology%3C%5C%2Fi%3E%20412%20%28September%205%2C%202015%29%3A%2065%26%23×2013%3B72.%20https%3A%5C%2F%5C%2Fdoi.org%5C%2F%3Ca%20class%3D%27zp-ItemURL%27%20target%3D%27_blank%27%20href%3D%2710.1016%5C%2Fj.mce.2015.05.028%27%3E10.1016%5C%2Fj.mce.2015.05.028%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Hepatic%20Nad%20Salvage%20Pathway%20Is%20Enhanced%20in%20Mice%20on%20a%20High-Fat%20Diet%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Melanie%22%2C%22lastName%22%3A%22Penke%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Per%20S.%22%2C%22lastName%22%3A%22Larsen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Susanne%22%2C%22lastName%22%3A%22Schuster%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Morten%22%2C%22lastName%22%3A%22Dall%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Benjamin%20A.%20H.%22%2C%22lastName%22%3A%22Jensen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Theresa%22%2C%22lastName%22%3A%22Gorski%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andrej%22%2C%22lastName%22%3A%22Meusel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Sandy%22%2C%22lastName%22%3A%22Richter%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Sara%20G.%22%2C%22lastName%22%3A%22Vienberg%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jonas%20T.%22%2C%22lastName%22%3A%22Treebak%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22Garten%22%7D%5D%2C%22abstractNote%22%3A%22Nicotinamide%20phosphoribosyltransferase%20%28Nampt%29%20is%20the%20rate-limiting%20enzyme%20for%20NAD%20salvage%20and%20the%20abundance%20of%20Nampt%20has%20been%20shown%20to%20be%20altered%20in%20non-alcoholic%20fatty%20liver%20disease.%20It%20is%2C%20however%2C%20unknown%20how%20hepatic%20Nampt%20is%20regulated%20in%20response%20to%20accumulation%20of%20lipids%20in%20the%20liver%20of%20mice%20fed%20a%20high-fat%20diet%20%28HFD%29.%20HFD%20mice%20gained%20more%20weight%2C%20stored%20more%20hepatic%20lipids%20and%20had%20an%20impaired%20glucose%20tolerance%20compared%20with%20control%20mice.%20NAD%20levels%20as%20well%20as%20Nampt%20mRNA%20expression%2C%20protein%20abundance%20and%20activity%20were%20significantly%20increased%20in%20HFD%20mice.%20Enhanced%20NAD%20levels%20were%20associated%20with%20deacetylation%20of%20p53%20and%20Nf%5Cu03bab%20indicating%20increased%20activation%20of%20Sirt1.%20Despite%20impaired%20glucose%20tolerance%20and%20increased%20hepatic%20lipid%20levels%20in%20HFD%20mice%2C%20NAD%20metabolism%20was%20significantly%20enhanced.%20Thus%2C%20improved%20NAD%20metabolism%20may%20be%20a%20compensatory%20mechanism%20to%20protect%20against%20negative%20impact%20of%20hepatic%20lipid%20accumulation.%22%2C%22date%22%3A%22September%205%2C%202015%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1016%5C%2Fj.mce.2015.05.028%22%2C%22ISSN%22%3A%221872-8057%22%2C%22url%22%3A%2210.1016%5C%2Fj.mce.2015.05.028%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-24T10%3A43%3A40Z%22%7D%7D%5D%7D
Ober, Peggy, Tanja Poulain, Christof Meigen, Ulrike Spielau, Carolin Sobek, Wieland Kiess, Ulrike Igel, Tobias Lipek, and Mandy Vogel. “Modifiable Factors Influencing Attention Performance in Healthy Children: Insights from a Comprehensive School Nutrition Study.” BMC Public Health 24, no. 1 (June 19, 2024): 1629. https://doi.org/10.1186/s12889-024-19059-8.
Sobek, Carolin, Peggy Ober, and Mandy Vogel. “Schulen im (Klima-)Wandel – Handlungsfelder.” Kinder- und Jugendmedizin 23, no. 4 (August 2023): 229–34. https://doi.org/10.1055/a-2104-3463.
Schmidt, Ricarda, Andreas Hiemisch, Wieland Kiess, Kai von Klitzing, Franziska Schlensog-Schuster, and Anja Hilbert. “Validation Study on the Child, Adult, and Parent Version of the ARFID Module 2.0 for the Eating Disorder Examination.” The International Journal of Eating Disorders 55, no. 12 (December 2022): 1708–20. https://doi.org/10.1002/eat.23805.
Sobek, Carolin, Peggy Ober, Sarah Abel, Ulrike Spielau, Wieland Kiess, Christof Meigen, Tanja Poulain, Ulrike Igel, Mandy Vogel, and Tobias Lipek. “Purchasing Behavior, Setting, Pricing, Family: Determinants of School Lunch Participation.” Nutrients 13, no. 12 (December 2021): 4209. https://doi.org/10.3390/nu13124209.
Menzel, Philipp, Mandy Vogel, Sean Austin, Norbert Sprenger, Nico Grafe, Cornelia Hilbert, Anne Jurkutat, Wieland Kiess, and Aristea Binia. “Concentrations of Oligosaccharides in Human Milk and Child Growth.” BMC Pediatrics 21, no. 1 (October 2021): 481. https://doi.org/10.1186/s12887-021-02953-0.
Poulain, Tanja, Ulrike Spielau, Mandy Vogel, Anne Dathan-Stumpf, Antje Körner, and Wieland Kiess. “Changes in Diet from Pregnancy to One Year After Birth: A Longitudinal Study.” BMC Pregnancy and Childbirth 21, no. 1 (September 2021): 600. https://doi.org/10.1186/s12884-021-04038-3.
Spielau, Ulrike, Mandy Vogel, Antje Körner, Wieland Kiess, and Tanja Poulain. “Composition and Culture of Eating (Cocu) Pregnancy: A New Short Questionnaire to Evaluate Diet Composition and Culture of Eating During Pregnancy.” Public Health Nutrition 24, no. 18 (June 2021): 6227–35. https://doi.org/10.1017/S1368980021002445.
Ober, Peggy, Carolin Sobek, Nancy Stein, Ulrike Spielau, Sarah Abel, Wieland Kiess, Christof Meigen, et al. “And yet Again: Having Breakfast Is Positively Associated with Lower Bmi and Healthier General Eating Behavior in Schoolchildren.” Nutrients 13, no. 4 (April 2021): 1351. https://doi.org/10.3390/nu13041351.
Schmidt, Ricarda, Andreas Hiemisch, Wieland Kiess, Kai von Klitzing, Franziska Schlensog-Schuster, and Anja Hilbert. “Macro- and Micronutrient Intake in Children with Avoidant/Restrictive Food Intake Disorder.” Nutrients 13, no. 2 (January 2021): 400. https://doi.org/10.3390/nu13020400.
Poulain, Tanja, Mandy Vogel, Christof Meigen, Ulrike Spielau, Andreas Hiemisch, and Wieland Kiess. “Parent-Child Agreement in Different Domains of Child Behavior and Health.” PloS One 15, no. 4 (2020): e0231462. https://doi.org/10.1371/journal.pone.0231462.
Schmidt, Ricarda, Andreas Hiemisch, Wieland Kiess, and Anja Hilbert. “Interaction Effects of Child Weight Status and Parental Feeding Practices on Children’s Eating Disorder Symptomatology.” Nutrients 11, no. 10 (October 2019): 2433. https://doi.org/10.3390/nu11102433.
Eichler, Janina, Ricarda Schmidt, Tanja Poulain, Andreas Hiemisch, Wieland Kiess, and Anja Hilbert. “Stability, Continuity, and Bi-Directional Associations of Parental Feeding Practices and Standardized Child Body Mass Index in Children from 2 to 12 Years of Age.” Nutrients 11, no. 8 (July 2019). https://doi.org/10.3390/nu11081751.
Eichler, Janina, Ricarda Schmidt, Andreas Hiemisch, Wieland Kiess, and Anja Hilbert. “Gestational Weight Gain, Physical Activity, Sleep Problems, Substance Use, and Food Intake as Proximal Risk Factors of Stress and Depressive Symptoms During Pregnancy.” BMC Pregnancy and Childbirth 19, no. 1 (May 2019): 175. https://doi.org/10.1186/s12884-019-2328-1.
Schmidt, Ricarda, Toralf Kirsten, Andreas Hiemisch, Wieland Kiess, and Anja Hilbert. “Interview-Based Assessment of Avoidant/Restrictive Food Intake Disorder (Arfid): A Pilot Study Evaluating an Arfid Module for the Eating Disorder Examination.” International Journal of Eating Disorders 52, no. 4 (March 2019): 388–97. https://doi.org/10.1002/eat.23063.
Poulain, Tanja, Ulrike Spielau, Mandy Vogel, Antje Körner, and Wieland Kiess. “Cocu: A New Short Questionnaire to Evaluate Diet Composition and Culture of Eating in Children and Adolescents.” Clinical Nutrition (Edinburgh, Scotland) 38, no. 6 (December 2018): 2858–65. https://doi.org/10.1016/j.clnu.2018.12.020.
Hartmann, Andrea S., Tanja Poulain, Mandy Vogel, Andreas Hiemisch, Wieland Kiess, and Anja Hilbert. “Correction to: Prevalence of Pica and Rumination Behaviors in German Children Aged 7-14 and Their Associations with Feeding, Eating, and General Psychopathology: A Population-Based Study.” European Child & Adolescent Psychiatry 27, no. 11 (November 2018): 1509. https://doi.org/10.1007/s00787-018-1179-z.
Händel, Norman, Thomas Mothes, David Petroff, Ronny Baber, Anne Jurkutat, Gunter Flemming, Wieland Kiess, et al. “Will the Real Coeliac Disease Please Stand Up? Coeliac Disease Prevalence in the German LIFE Child Study.” Journal of Pediatric Gastroenterology and Nutrition 67, no. 4 (October 2018): 494. https://doi.org/10.1097/MPG.0000000000002052.
Schmidt, Ricarda, Mandy Vogel, Andreas Hiemisch, Wieland Kiess, and Anja Hilbert. “Pathological and Non-Pathological Variants of Restrictive Eating Behaviors in Middle Childhood: A Latent Class Analysis.” Appetite 127 (August 2018): 257–65. https://doi.org/10.1016/j.appet.2018.04.030.
Hartmann, Andrea S., Tanja Poulain, Mandy Vogel, Andreas Hiemisch, Wieland Kiess, and Anja Hilbert. “Prevalence of Pica and Rumination Behaviors in German Children Aged 7-14 and Their Associations with Feeding, Eating, and General Psychopathology: A Population-Based Study.” European Child & Adolescent Psychiatry 27, no. 11 (April 2018): 1499–1508. https://doi.org/10.1007/s00787-018-1153-9.
Kliem, Sören, Ricarda Schmidt, Mandy Vogel, Andreas Hiemisch, Wieland Kiess, and Anja Hilbert. “An 8-Item Short Form of the Eating Disorder Examination-Questionnaire Adapted for Children (ChEDE-Q8).” International Journal of Eating Disorders 50, no. 6 (June 2017): 679–86. https://doi.org/10.1002/eat.22658.
Schmidt, Ricarda, Robert Richter, Anne Brauhardt, Andreas Hiemisch, Wieland Kiess, and Anja Hilbert. “Parental Feeding Practices in Families with Children Aged 2–13 Years: Psychometric Properties and Child Age-Specific Norms of the German Version of the Child Feeding Questionnaire (Cfq).” Appetite 109 (February 2017): 154–64. https://doi.org/10.1016/j.appet.2016.11.038.
Sonnengrün, Lilli, Celestina Schober, Mandy Vogel, Andreas Hiemisch, Mirko Döhnert, Anja Hilbert, and Wieland Kiess. “Feeding, Eating and Behavioral Disturbances in Prader-Willi Syndrome and Non-Syndromal Obesity.” Journal of Pediatric Endocrinology and Metabolism 29, no. 8 (June 2016): 923–32. https://doi.org/10.1515/jpem-2016-0085.
Penke, Melanie, Per S. Larsen, Susanne Schuster, Morten Dall, Benjamin A. H. Jensen, Theresa Gorski, Andrej Meusel, et al. “Hepatic Nad Salvage Pathway Is Enhanced in Mice on a High-Fat Diet.” Molecular and Cellular Endocrinology 412 (September 5, 2015): 65–72. https://doi.org/10.1016/j.mce.2015.05.028.
2390247
T52N9QLZ
obesity
1
chicago-fullnote-bibliography
50
date
desc
1
1
6748
https://home.uni-leipzig.de/lifechild/wp-content/plugins/zotpress/
%7B%22status%22%3A%22success%22%2C%22updateneeded%22%3Afalse%2C%22instance%22%3Afalse%2C%22meta%22%3A%7B%22request_last%22%3A0%2C%22request_next%22%3A0%2C%22used_cache%22%3Atrue%7D%2C%22data%22%3A%5B%7B%22key%22%3A%22SHIYK6W6%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22lastModifiedByUser%22%3A%7B%22id%22%3A5423163%2C%22username%22%3A%22erossi19%22%2C%22name%22%3A%22%22%2C%22links%22%3A%7B%22alternate%22%3A%7B%22href%22%3A%22https%3A%5C%2F%5C%2Fwww.zotero.org%5C%2Ferossi19%22%2C%22type%22%3A%22text%5C%2Fhtml%22%7D%7D%7D%2C%22creatorSummary%22%3A%22Wagner%20et%20al.%22%2C%22parsedDate%22%3A%222024-07-22%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EWagner%2C%20Friederike%2C%20Robert%20Zeidler%2C%20Uta%20Ceglarek%2C%20Wieland%20Kiess%2C%20J%26%23xFC%3Brgen%20Kratzsch%2C%20Alexander%20Gaudl%2C%20Ronald%20Biemann%2C%20and%20Mandy%20Vogel.%20%26%23x201C%3BObesity%20Is%20Associated%20with%20Increased%2011-Oxyandrogen%20Serum%20Concentrations%20during%20Puberty.%26%23x201D%3B%20%3Ci%3EHormone%20Research%20in%20Paediatrics%3C%5C%2Fi%3E%2C%20July%2022%2C%202024.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1159%5C%2F000540433%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1159%5C%2F000540433%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Obesity%20is%20associated%20with%20increased%2011-oxyandrogen%20serum%20concentrations%20during%20puberty%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Friederike%22%2C%22lastName%22%3A%22Wagner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Robert%22%2C%22lastName%22%3A%22Zeidler%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Uta%22%2C%22lastName%22%3A%22Ceglarek%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J%5Cu00fcrgen%22%2C%22lastName%22%3A%22Kratzsch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Alexander%22%2C%22lastName%22%3A%22Gaudl%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ronald%22%2C%22lastName%22%3A%22Biemann%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%5D%2C%22abstractNote%22%3A%22Introduction%3A%20While%20the%20influence%20of%20various%20factors%20on%20classical%20androgen%20synthesis%20in%20children%20and%20adolescents%20and%20its%20impact%20on%20puberty%20has%20been%20widely%20investigated%2C%20there%20appear%20to%20be%20gaps%20and%20contradictory%20findings%20regarding%20the%20association%20of%20overweight%20and%20obesity%20with%20the%20synthesis%20of%20adrenal-derived%2011-oxygenated%20androgen%20%2811-OA%29%20serum%20levels.%20With%20this%20study%2C%20we%20aimed%20to%20examine%20how%20overweight%20and%20obesity%20affect%2011-OA%20serum%20levels%20during%20puberty%20in%20a%20large%20cohort%20of%20children%20and%20adolescents.%5CnMethods%3A%20Our%20cohort%20comprised%201%2C054%20healthy%20children%20aged%206%20to%2019%20years%20providing%20serum%20samples%20at%20a%20total%20of%201%2C734%20visits.%20Liquid%20chromatography-tandem%20mass%20spectrometry%20was%20used%20to%20quantify%2011-ketotestosterone%20%2811KT%29%2C%2011-ketoandrostendione%20%2811-KA4%29%2C%2011-%5Cu00df-hydroxytestosterone%20%2811-OHT%29%2C%2011-%5Cu00df-hydroxyandrostendione%20%2811OHA4%29%2C%20testosterone%2C%20androstenedione%2C%20and%20DHEAS.%20In%20addition%2C%20we%20assessed%20BMI-SDSs%3B%20skinfold%20thicknesses%3B%20and%20Tanner%20stages.%20The%20significance%20level%20%5Cu03b1%20was%20set%20to%20%5Cu03b1%3D0.05.%5CnResults%3A%20Increases%20in%2011-KT%2C%2011-KA4%2C%2011-OHT%2C%20and%2011-OHA4%20levels%20were%20observed%20in%20boys%20and%20girls%20during%20puberty.%2011-KT%20%28%5Cu00df%3D0.2%2C%20p%3C0.001%29%2C%2011-KA4%20%28%5Cu00df%3D0.16%2C%20p%3C0.001%29%20and%2011-OHA4%20%28%5Cu00df%3D0.12%2C%20p%3D0.003%29%20were%20positively%20correlated%20with%20BMI%20in%20boys%20age%2013%20and%20under.%2011-KT%20%28%5Cu00df%3D0.1%2C%20p%3D0.047%29%20was%20positively%20correlated%20with%20BMI%20in%20girls%20age%2011%20and%20under.%2011-OHT%20was%20positively%20correlated%20with%20BMI%20independent%20of%20age%20%28boys%2013%20and%20under%3A%20%5Cu00df%3D0.17%2C%20p%3C0.001%3B%20over%2013%20years%3A%20%5Cu00df%3D0.14%2C%20p%3D0.001%3B%20girls%2011%20and%20under%3A%20%5Cu00df%3D0.17%2C%20p%3C0.001%3B%20over%2011%20years%3A%20%5Cu00df%3D0.18%2C%20p%3C0.001%29.%5CnConclusion%3A%20We%20found%20increasing%2011-OA%20serum%20levels%20throughout%20all%20Tanner%20stages.%2011-OAs%20were%20observed%20to%20be%20associated%20with%20BMI%20and%20skinfold%20thickness%2C%20suggesting%20that%20overweight%20and%20obesity%20may%20be%20associated%20with%20pubertal%20alterations%20in%2011-OA%20serum%20levels.%22%2C%22date%22%3A%222024-7-22%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1159%5C%2F000540433%22%2C%22ISSN%22%3A%221663-2818%2C%201663-2826%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fkarger.com%5C%2Fdoi%5C%2F10.1159%5C%2F000540433%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222024-08-27T12%3A20%3A40Z%22%7D%7D%2C%7B%22key%22%3A%22K5XMVMIN%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Fechner%20et%20al.%22%2C%22parsedDate%22%3A%222024-06-15%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EFechner%2C%20Anna%2C%20Anja%20Willenberg%2C%20Niels%20Ziegelasch%2C%20Andreas%20Merkenschlager%2C%20Wieland%20Kiess%2C%20and%20Mandy%20Vogel.%20%26%23x201C%3BCreatine%20Kinase%20Serum%20Levels%20in%20Children%20Revisited%3A%20New%20Reference%20Intervals%20from%20a%20Large%20Cohort%20of%20Healthy%20Children%20and%20Adolescents.%26%23x201D%3B%20%3Ci%3EClinica%20Chimica%20Acta%3C%5C%2Fi%3E%20560%20%28June%2015%2C%202024%29%3A%20119726.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.cca.2024.119726%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.cca.2024.119726%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Creatine%20kinase%20serum%20levels%20in%20children%20revisited%3A%20New%20reference%20intervals%20from%20a%20large%20cohort%20of%20healthy%20children%20and%20adolescents%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anna%22%2C%22lastName%22%3A%22Fechner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anja%22%2C%22lastName%22%3A%22Willenberg%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Niels%22%2C%22lastName%22%3A%22Ziegelasch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andreas%22%2C%22lastName%22%3A%22Merkenschlager%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%5D%2C%22abstractNote%22%3A%22Background%5CnCreatine%20Kinase%20%28CK%29%20has%20become%20increasingly%20important%20in%20pediatrics%20as%20a%20commonly%20used%20laboratory%20screening%20parameter%20for%20neuromuscular%20diseases.%20Recent%20research%20suggests%20that%20hyperCKemia%20in%20children%20is%20not%20always%20associated%20with%20pathology%20and%20can%20occur%20due%20to%20several%20reasons.%20Little%20is%20known%20of%20various%20clinical%20factors%20that%20may%20influence%20CK%20throughout%20child%20development.%5CnObjective%5CnThis%20study%20aimed%20to%20establish%20reliable%20age-%20and%20sex-specific%20reference%20ranges%20for%20serum%20CK%20levels%20in%20healthy%20infants%2C%20children%2C%20and%20adolescents.%20In%20addition%2C%20the%20effect%20of%20puberty%2C%20oral%20contraceptive%20%28OC%29%20use%20as%20well%20as%20steroid%20hormones%20on%20CK%20was%20examined.%5CnMaterials%20and%20methods%5CnThe%20data%20was%20collected%20from%20subjects%20of%20the%20longitudinal%20population-based%20%5Cu201cLIFE%20Child%5Cu201d-cohort%20between%202011%20and%202016%20in%20Leipzig%2C%20Germany.%205238%20blood%20samples%20of%202707%20healthy%20children%2C%20aged%20between%200.14%5Cu00a0months%20and%2018%5Cu00a0years%2C%20were%20analyzed.%5CnResults%5CnSerum%20CK%20levels%20raised%20during%20the%20first%20year%20of%20life%2C%20peaking%20shortly%20after%20age%20one%20%28P50girls%5Cu00a0%3D%5Cu00a02.7%20%5Cu00b5kat%5C%2FL%2C%20P50boys%5Cu00a0%3D%5Cu00a02.90%20%5Cu00b5kat%5C%2FL%29.%20There%20was%20a%20pronounced%20difference%20in%20the%2097.5th%20percentile%20between%20boys%20and%20girls%20during%20adolescence%20with%20its%20maximum%20at%20age%2018%20%28P97.5girls%5Cu00a0%3D%5Cu00a05.74%20%5Cu00b5kat%5C%2FL%2C%20P97.5boys%3D%2014.48%20%5Cu00b5kat%5C%2FL%29.%20Also%2C%20mean%20CK%20serum%20levels%20were%20significantly%20higher%20in%20boys%20%28bboys%5Cu00a0%3D%5Cu00a00.29%2C%20pboys%5Cu00a0%3C%5Cu00a00.001%29.%20Intake%20of%20oral%20contraceptives%20%28OC%29%2C%20extreme%20underweight%2C%20underweight%20and%20obesity%20revealed%20a%20significant%20inverse%20correlation%20with%20CK%20serum%20levels.%5CnConclusion%5CnAge%2C%20sex%2C%20OC%20intake%20and%20weight%20status%20affect%20serum%20CK%20levels%2C%20particularly%20during%20infancy%20and%20puberty.%20We%20recommend%20the%20use%20of%20age-%20and%20sex-specific%20reference%20values%20for%20CK%20serum%20levels%20to%20assess%20the%20clinical%20relevance%20of%20measurements.%22%2C%22date%22%3A%222024-06-15%22%2C%22language%22%3A%22%22%2C%22DOI%22%3A%2210.1016%5C%2Fj.cca.2024.119726%22%2C%22ISSN%22%3A%220009-8981%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.sciencedirect.com%5C%2Fscience%5C%2Farticle%5C%2Fpii%5C%2FS0009898124019788%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222024-06-04T05%3A31%3A27Z%22%7D%7D%2C%7B%22key%22%3A%22EB3A53J6%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Barzen%20et%20al.%22%2C%22parsedDate%22%3A%222024-04-13%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EBarzen%2C%20Charlotte%2C%20Mandy%20Vogel%2C%20Wieland%20Kiess%2C%20and%20Tanja%20Poulain.%20%26%23x201C%3BAssociations%20between%20Gestational%20Weight%20Gain%20and%20Weight%20Development%20of%20the%20Offspring%3A%20Differences%20Depending%20on%20Maternal%20Pre-Pregnancy%20BMI.%26%23x201D%3B%20%3Ci%3EArchives%20of%20Gynecology%20and%20Obstetrics%3C%5C%2Fi%3E%2C%20April%2013%2C%202024.%20%3Ca%20class%3D%27zp-ItemURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs00404-024-07487-1%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs00404-024-07487-1%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Associations%20between%20gestational%20weight%20gain%20and%20weight%20development%20of%20the%20offspring%3A%20Differences%20depending%20on%20maternal%20pre-pregnancy%20BMI%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Charlotte%22%2C%22lastName%22%3A%22Barzen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%5D%2C%22abstractNote%22%3A%22Obesity%20rates%20are%20rising%2C%20and%20the%20gestational%20weight%20gain%20%28GWG%29%20of%20most%20women%20does%20not%20comply%20with%20current%20guidelines.%20This%20study%20assesses%20the%20association%20of%20pre-pregnancy%20BMI%20%28ppBMI%29%20and%20GWG%20with%20the%20child%5Cu2019s%20weight%20development%20and%20investigates%20whether%20associations%20with%20GWG%20differ%20depending%20on%20ppBMI.%22%2C%22date%22%3A%222024-04-13%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1007%5C%2Fs00404-024-07487-1%22%2C%22ISSN%22%3A%221432-0711%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs00404-024-07487-1%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222024-04-15T06%3A03%3A53Z%22%7D%7D%2C%7B%22key%22%3A%22EFN9XGX2%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22lastModifiedByUser%22%3A%7B%22id%22%3A1995470%2C%22username%22%3A%22mvogel78%22%2C%22name%22%3A%22%22%2C%22links%22%3A%7B%22alternate%22%3A%7B%22href%22%3A%22https%3A%5C%2F%5C%2Fwww.zotero.org%5C%2Fmvogel78%22%2C%22type%22%3A%22text%5C%2Fhtml%22%7D%7D%7D%2C%22creatorSummary%22%3A%22Krause%20et%20al.%22%2C%22parsedDate%22%3A%222023-11-23%22%2C%22numChildren%22%3A3%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EKrause%2C%20Lea%2C%20Tanja%20Poulain%2C%20Wieland%20Kiess%2C%20and%20Mandy%20Vogel.%20%26%23x201C%3BBody%20Image%20and%20Behavioural%20and%20Emotional%20Difficulties%20in%20German%20Children%20and%20Adolescents.%26%23x201D%3B%20%3Ci%3EBMC%20Pediatrics%3C%5C%2Fi%3E%2023%2C%20no.%201%20%28November%2023%2C%202023%29%3A%20594.%20%3Ca%20class%3D%27zp-ItemURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs12887-023-04405-3%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs12887-023-04405-3%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Body%20image%20and%20behavioural%20and%20emotional%20difficulties%20in%20German%20children%20and%20adolescents%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Lea%22%2C%22lastName%22%3A%22Krause%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%5D%2C%22abstractNote%22%3A%22Behavioural%20and%20emotional%20difficulties%20might%20play%20an%20important%20role%20in%20the%20development%20of%20body%20image%20disturbances%2C%20which%20represent%20serious%20risk%20factors%20for%20eating%20disorders%20or%20depression.%20The%20present%20study%20provides%20a%20detailed%20overview%20on%20body%20image%20disturbances%20and%20several%20behavioural%20and%20emotional%20difficulties%20%28differences%20between%20gender%2C%20age%2C%20and%20weight%20status%29%20and%20their%20inter-relations%20in%20German%20children%20and%20adolescents.%22%2C%22date%22%3A%222023-11-23%22%2C%22language%22%3A%22%22%2C%22DOI%22%3A%2210.1186%5C%2Fs12887-023-04405-3%22%2C%22ISSN%22%3A%221471-2431%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs12887-023-04405-3%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222024-08-27T10%3A18%3A31Z%22%7D%7D%2C%7B%22key%22%3A%22Q8BWZ4IW%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Bier%20et%20al.%22%2C%22parsedDate%22%3A%222023-11%22%2C%22numChildren%22%3A2%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EBier%2C%20Elisabeth%2C%20Mandy%20Vogel%2C%20Nico%20Grafe%2C%20Anne%20Jurkutat%2C%20Juliane%20Ludwig%2C%20Oleg%20Wagner%2C%20Christof%20Meigen%2C%20Wieland%20Kiess%2C%20and%20Tanja%20Poulain.%20%26%23x201C%3BChildren%26%23×2019%3Bs%20Satisfaction%20with%20a%20Comprehensive%20Study%20Program-Results%20from%20the%20LIFE%20Child%20Cohort%20Study.%26%23x201D%3B%20%3Ci%3EPaediatric%20and%20Perinatal%20Epidemiology%3C%5C%2Fi%3E%2037%2C%20no.%208%20%28November%202023%29%3A%20704%26%23×2013%3B9.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fppe.13007%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fppe.13007%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Children%27s%20satisfaction%20with%20a%20comprehensive%20study%20program-Results%20from%20the%20LIFE%20Child%20cohort%20study%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Elisabeth%22%2C%22lastName%22%3A%22Bier%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Nico%22%2C%22lastName%22%3A%22Grafe%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anne%22%2C%22lastName%22%3A%22Jurkutat%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Juliane%22%2C%22lastName%22%3A%22Ludwig%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Oleg%22%2C%22lastName%22%3A%22Wagner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christof%22%2C%22lastName%22%3A%22Meigen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%5D%2C%22abstractNote%22%3A%22BACKGROUND%3A%20Research%20participants%27%20satisfaction%20is%20a%20topic%20of%20great%20interest%2C%20especially%20in%20the%20context%20of%20longitudinal%20studies.%20Evaluation%20also%20represents%20an%20important%20component%20of%20quality%20management%20in%20the%20health%20care%20system.%20Adult%20studies%20found%20that%20personal%20characteristics%2C%20e.g.%2C%20age%2C%20sex%2C%20ethnicity%2C%20and%20SES%2C%20can%20influence%20satisfaction%20with%20health%20care%20or%20study%20participation.%20Studies%20on%20paediatric%20participants%20are%20sparse.%5CnOBJECTIVES%3A%20To%20examine%20how%20children%20rated%20the%20study%20day%20of%20a%20cohort%20study%20and%20how%20these%20ratings%20were%20associated%20with%20sociodemographic%20and%20socioeconomic%20characteristics%20and%20retention%20in%20the%20context%20of%20a%20large%20cohort%20study.%5CnMETHODS%3A%20Analyses%20were%20performed%20on%204-%20to%2017-year-old%20participants%20of%20the%20German%20longitudinal%20cohort%20study%20LIFE%20Child%20%28n%5Cu2009%3D%5Cu20092033%29.%20To%20assess%20the%20associations%20between%20overall%20satisfaction%20%28high%20versus%20low%5C%2Fmiddle%29%20and%20age%2C%20sex%2C%20body-mass%20index%2C%20socioecomonic%20status%2C%20and%20participation%20in%20a%20follow-up%20visit%2C%20we%20applied%20logistic%20mixed-effects%20models.%5CnRESULTS%3A%20Participants%27%20overall%20satisfaction%20with%20the%20LIFE%20Child%20study%20day%20was%20high%20%28%5C%22very%20good%5C%22%3A%2067.8%25%29.%20Overall%20satisfaction%20was%20higher%20in%207-9%5Cu2009years%20olds%20%28odds%20ratio%20%5BOR%5D%202.00%2C%2095%25%20confidence%20interval%20%5BCI%201.51%2C%202.66%29%20and%2010-12%5Cu2009years%20olds%20%28OR%201.51%2C%2095%25%20CI%201.16%2C%201.98%29%20than%20in%204-6%5Cu2009years%20olds%20and%2013-17%20years%20olds.%20Children%20with%20obesity%20were%20less%20likely%20to%20participate%20in%20a%20follow-up%20visit%20%28OR%200.56%2C%2095%25%20CI%200.39%2C%200.78%29.%20Children%20reporting%20high%20overall%20satisfaction%20at%20the%20first%20study%20visit%20completed%20a%20follow-up%20visit%20more%20frequently%20%28OR%201.32%2C%2095%25%20CI%201.05%2C1.67%29.%5CnCONCLUSIONS%3A%20A%20high%20level%20of%20satisfaction%20increased%20participants%27%20attendance%20at%20a%20follow-up%20visit.%20Our%20results%20might%20be%20helpful%20for%20adapting%20the%20study%20program%20to%20the%20participants%27%20needs%20in%20order%20to%20maximise%20retention%20and%20minimise%20attrition%20rates.%22%2C%22date%22%3A%222023-11%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1111%5C%2Fppe.13007%22%2C%22ISSN%22%3A%221365-3016%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222024-08-13T12%3A49%3A47Z%22%7D%7D%2C%7B%22key%22%3A%22FU7YHBMQ%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Stein%20et%20al.%22%2C%22parsedDate%22%3A%222023-10-01%22%2C%22numChildren%22%3A2%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EStein%2C%20Robert%2C%20Eric%20G%26%23xF6%3Bpel%2C%20Daniel%20Weghuber%2C%20Maximiliane%20Chiara%20Hammel%2C%20Mandy%20Vogel%2C%20Wieland%20Kiess%2C%20and%20Antje%20K%26%23xF6%3Brner.%20%26%23x201C%3BAre%20There%20Relevant%20Thresholds%20of%20Insulin-Independent%20Indices%20across%20the%20Lifespan%20to%20Predict%20Alterations%20in%20Glycemic%20Control%3F%26%23×2014%3BAuthors%26%23×2019%3B%20Reply.%26%23x201D%3B%20%3Ci%3EThe%20Lancet%20Regional%20Health%20-%20Europe%3C%5C%2Fi%3E%2033%20%28October%201%2C%202023%29%3A%20100734.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.lanepe.2023.100734%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.lanepe.2023.100734%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Are%20there%20relevant%20thresholds%20of%20insulin-independent%20indices%20across%20the%20lifespan%20to%20predict%20alterations%20in%20glycemic%20control%3F%5Cu2014Authors%5Cu2019%20reply%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Robert%22%2C%22lastName%22%3A%22Stein%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Eric%22%2C%22lastName%22%3A%22G%5Cu00f6pel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Daniel%22%2C%22lastName%22%3A%22Weghuber%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Maximiliane%20Chiara%22%2C%22lastName%22%3A%22Hammel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%5D%2C%22abstractNote%22%3A%22%22%2C%22date%22%3A%222023-10-01%22%2C%22language%22%3A%22%22%2C%22DOI%22%3A%2210.1016%5C%2Fj.lanepe.2023.100734%22%2C%22ISSN%22%3A%222666-7762%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.sciencedirect.com%5C%2Fscience%5C%2Farticle%5C%2Fpii%5C%2FS2666776223001539%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222024-08-27T12%3A49%3A43Z%22%7D%7D%2C%7B%22key%22%3A%22S2ZWAVJH%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Hammel%20et%20al.%22%2C%22parsedDate%22%3A%222023-07%22%2C%22numChildren%22%3A2%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EHammel%2C%20Maximiliane%20Chiara%2C%20Robert%20Stein%2C%20J%26%23xFC%3Brgen%20Kratzsch%2C%20Mandy%20Vogel%2C%20Alexander%20J.%20Eckert%2C%20Rima%20Destya%20Triatin%2C%20Marco%20Colombo%2C%20et%20al.%20%26%23x201C%3BFasting%20Indices%20of%20Glucose-Insulin-Metabolism%20across%20Life%20Span%20and%20Prediction%20of%20Glycemic%20Deterioration%20in%20Children%20with%20Obesity%20from%20New%20Diagnostic%20Cut-Offs.%26%23x201D%3B%20%3Ci%3EThe%20Lancet%20Regional%20Health.%20Europe%3C%5C%2Fi%3E%2030%20%28July%202023%29%3A%20100652.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.lanepe.2023.100652%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.lanepe.2023.100652%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Fasting%20indices%20of%20glucose-insulin-metabolism%20across%20life%20span%20and%20prediction%20of%20glycemic%20deterioration%20in%20children%20with%20obesity%20from%20new%20diagnostic%20cut-offs%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Maximiliane%20Chiara%22%2C%22lastName%22%3A%22Hammel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Robert%22%2C%22lastName%22%3A%22Stein%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J%5Cu00fcrgen%22%2C%22lastName%22%3A%22Kratzsch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Alexander%20J.%22%2C%22lastName%22%3A%22Eckert%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Rima%20Destya%22%2C%22lastName%22%3A%22Triatin%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Marco%22%2C%22lastName%22%3A%22Colombo%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christof%22%2C%22lastName%22%3A%22Meigen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ronny%22%2C%22lastName%22%3A%22Baber%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Juraj%22%2C%22lastName%22%3A%22Stanik%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ulrike%22%2C%22lastName%22%3A%22Spielau%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anette%22%2C%22lastName%22%3A%22Stoltze%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Kerstin%22%2C%22lastName%22%3A%22Wirkner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anke%22%2C%22lastName%22%3A%22T%5Cu00f6njes%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Harold%22%2C%22lastName%22%3A%22Snieder%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Reinhard%20W.%22%2C%22lastName%22%3A%22Holl%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Michael%22%2C%22lastName%22%3A%22Stumvoll%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Matthias%22%2C%22lastName%22%3A%22Bl%5Cu00fcher%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%5D%2C%22abstractNote%22%3A%22BACKGROUND%3A%20Fasting%20indices%20of%20glucose-insulin-metabolism%20are%20an%20easy%20and%20affordable%20tool%20to%20assess%20insulin%20resistance.%20We%20aimed%20to%20establish%20reference%20ranges%20for%20fasting%20insulin%20indices%20that%20reflect%20age-dependent%20variation%20over%20the%20entire%20life%20span%20and%20subsequently%20test%20their%20clinical%20application%20regarding%20the%20prediction%20of%20glycemic%20deterioration%20in%20children.%5CnMETHODS%3A%20We%20calculated%20age-%20and%20puberty-dependent%20reference%20values%20for%20HOMA-IR%2C%20HOMA2-IR%2C%20HOMA-%5Cu03b2%2C%20McAuley%20index%2C%20fasting%20insulin%2C%20and%20fasting%20glucose%20from%206994%20observations%20of%205512%20non-obese%20healthy%20subjects%20aged%205-80%20years.%20Applying%20those%20references%2C%20we%20determined%20the%20prevalence%20of%20insulin%20resistance%20among%202538%20subjects%20with%20obesity.%20Furthermore%2C%20we%20investigated%20the%20intraindividual%20stability%20and%20the%20predictive%20values%20for%20future%20dysglycemia%20of%20these%20fasting%20indices%20in%20516%20children%20and%20adolescents%20with%20obesity%20up%20to%2019%20years%20of%20follow-up.%20We%20validated%20the%20results%20in%20three%20independent%20cohorts.%5CnFINDINGS%3A%20There%20was%20a%20strong%20age-dependent%20variation%20of%20all%20indices%20throughout%20the%20life%20span%2C%20including%20prolonged%20recovery%20of%20pubertal%20insulin%20resistance%20and%20a%20subsequent%20continuous%20increase%20throughout%20adulthood.%20Already%20from%20age%205%20years%20onwards%2C%20%3E40%25%20of%20children%20with%20obesity%20presented%20with%20elevated%20parameters%20of%20insulin%20resistance.%20Applying%20newly%20developed%20reference%20ranges%2C%20insulin%20resistance%20among%20children%20with%20obesity%20doubled%20the%20risk%20for%20future%20glycemic%20deterioration%20%28HOMA-IR%20HR%201.88%20%2895%25%20CI%201.1-3.21%29%29%2C%20fasting%20insulin%20HR%201.89%20%2895%25%20CI%201.11-3.23%29.%20In%20contrast%2C%20fasting%20glucose%20alone%20was%20not%20predictive%20for%20emerging%20dysglycemia%20in%20children%20with%20obesity%20%28HR%201.03%20%2895%25%20CI%200.62-1.71%29%29.%20The%20new%20insulin-based%20thresholds%20were%20superior%20to%20fasting%20glucose%20and%20HbA1c%20in%20detecting%20children%20eventually%20manifesting%20with%20dysglycemia%20in%20prospective%20analyses.%5CnINTERPRETATION%3A%20The%20variation%20of%20fasting%20glucose-insulin-metabolism%20across%20the%20life%20span%20necessitates%20age-specific%20reference%20ranges.%20The%20improved%20prediction%20of%20future%20glycemic%20deterioration%20by%20indices%20based%20on%20fasting%20insulin%20beyond%20simple%20glucose%20measures%20alone%20could%20help%20to%20stratify%20risk%20characteristics%20of%20children%20with%20obesity%20in%20order%20to%20guide%20patient-tailored%20prevention%20and%20intervention%20approaches.%5CnFUNDING%3A%20German%20Research%20Foundation%20%28DFG%29-through%20SFB%201052%2C%20project%20number%20209933838%2C%20subproject%20C5%3B%20Federal%20Ministry%20of%20Education%20and%20Research%2C%20Germany%3B%20European%20Union-European%20Regional%20Development%20Fund%3B%20Free%20State%20of%20Saxony.%20The%20German%20Diabetes%20Association%2C%20the%20CarbHealth%20consortium%20%2801EA1908B%29.%20EU-IMI2-Consortium%20SOPHIA%20%28grant%20agreement%20No%20875534%29%2C%20German%20Center%20for%20Diabetes%20Research%20%28DZD%29%2C%20grant%20number%2082DZD14E03.%22%2C%22date%22%3A%222023-07%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1016%5C%2Fj.lanepe.2023.100652%22%2C%22ISSN%22%3A%222666-7762%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222024-06-17T12%3A11%3A40Z%22%7D%7D%2C%7B%22key%22%3A%22KL5QE2N4%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22F%5Cu00f6rster%20et%20al.%22%2C%22parsedDate%22%3A%222023-01-19%22%2C%22numChildren%22%3A2%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EF%26%23xF6%3Brster%2C%20Lucas-Johann%2C%20Mandy%20Vogel%2C%20Robert%20Stein%2C%20Anja%20Hilbert%2C%20Julius%20Lars%20Breinker%2C%20Marleen%20B%26%23xF6%3Bttcher%2C%20Wieland%20Kiess%2C%20and%20Tanja%20Poulain.%20%26%23x201C%3BMental%20Health%20in%20Children%20and%20Adolescents%20with%20Overweight%20or%20Obesity.%26%23x201D%3B%20%3Ci%3EBMC%20Public%20Health%3C%5C%2Fi%3E%2023%2C%20no.%201%20%28January%2019%2C%202023%29%3A%20135.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs12889-023-15032-z%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs12889-023-15032-z%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Mental%20health%20in%20children%20and%20adolescents%20with%20overweight%20or%20obesity%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Lucas-Johann%22%2C%22lastName%22%3A%22F%5Cu00f6rster%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Robert%22%2C%22lastName%22%3A%22Stein%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anja%22%2C%22lastName%22%3A%22Hilbert%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Julius%20Lars%22%2C%22lastName%22%3A%22Breinker%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Marleen%22%2C%22lastName%22%3A%22B%5Cu00f6ttcher%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%5D%2C%22abstractNote%22%3A%22BACKGROUND%3A%20Overweight%20and%20obesity%20represent%20huge%20concerns%20for%20children%27s%20physical%20and%20mental%20well-being.%20This%20study%20examined%20the%20relationship%20between%20body%20mass%20index%20%28BMI%29%20and%20health-related%20quality%20of%20life%20%28HRQoL%29%2C%20somatoform%20complaints%2C%20and%20behavioral%20problems%20in%20children%20and%20adolescents.%20Additionally%2C%20the%20influence%20of%20sex%2C%20age%2C%20and%20socioeconomic%20status%20%28SES%29%20on%20these%20associations%20was%20considered.%5CnMETHODS%3A%20In%20total%2C%20we%20studied%202350%20participants%20between%20the%20ages%20of%204%20and%2018%20years%20%281213%204-%20to%2010-years-old%20%28child%20sample%29%20and%201137%2011-to%2018-year-olds%20%28adolescent%20sample%29%29.%20To%20assess%20HRQoL%2C%20somatoform%20complaints%2C%20and%20behavioral%20difficulties%2C%20we%20applied%20the%20KIDSCREEN-27%2C%20a%20short%20form%20of%20the%20Giessen%20Complaints%20Questionnaire%2C%20and%20the%20Strengths%20and%20Difficulties%20Questionnaire%20%28SDQ%29.%20The%20BMI%20was%20transformed%20to%20BMI%20standard%20deviation%20scores%20%28BMI-SDS%29%2C%20according%20to%20German%20gender-%20and%20age-specific%20reference%20data.%20Associations%20were%20investigated%20using%20linear%20regression%20analyses.%20Each%20association%20was%20checked%20for%20interaction%20with%20sex%2C%20age%2C%20and%20SES.%5CnRESULTS%3A%20Regarding%20HRQoL%2C%20we%20found%20worsening%20scores%20in%20physical%20well-being%20and%20psychological%20well-being%20with%20increasing%20BMI-SDS.%20Somatoform%20complaints%20were%20not%20significantly%20associated%20with%20BMI-SDS.%20Conduct%20problems%2C%20peer%20relationship%20problems%2C%20and%20emotional%20problems%20%28the%20latter%20only%20in%20the%20adolescent%20sample%29%20were%20positively%20associated%20with%20BMI-SDS.%20While%20we%20did%20not%20observe%20any%20significant%20interactions%20with%20sex%2C%20we%20found%20some%20significant%20interactions%20with%20age%20and%5C%2For%20SES.%5CnCONCLUSION%3A%20Our%20findings%20highlight%20the%20importance%20of%20mental%20difficulties%20in%20children%20and%20adolescents%20with%20higher%20BMI%20and%2C%20consequently%2C%20underline%20the%20relevance%20of%20including%20psychological%20interventions%20in%20the%20treatment%20of%20overweight%20or%20obesity.%22%2C%22date%22%3A%222023-01-19%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1186%5C%2Fs12889-023-15032-z%22%2C%22ISSN%22%3A%221471-2458%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-21T12%3A08%3A50Z%22%7D%7D%2C%7B%22key%22%3A%22UDCNY4UG%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Stein%20et%20al.%22%2C%22parsedDate%22%3A%222023-01%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EStein%2C%20Robert%2C%20Florian%20Koutny%2C%20Johannes%20Riedel%2C%20Natascha%20D%26%23xF6%3Brr%2C%20Klara%20Meyer%2C%20Marco%20Colombo%2C%20Mandy%20Vogel%2C%20et%20al.%20%26%23x201C%3BSingle%20Point%20Insulin%20Sensitivity%20Estimator%20%28SPISE%29%20as%20a%20Prognostic%20Marker%20for%20Emerging%20Dysglycemia%20in%20Children%20with%20Overweight%20or%20Obesity.%26%23x201D%3B%20%3Ci%3EMetabolites%3C%5C%2Fi%3E%2013%2C%20no.%201%20%28January%202023%29%3A%20100.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Fmetabo13010100%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Fmetabo13010100%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Single%20Point%20Insulin%20Sensitivity%20Estimator%20%28SPISE%29%20as%20a%20Prognostic%20Marker%20for%20Emerging%20Dysglycemia%20in%20Children%20with%20Overweight%20or%20Obesity%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Robert%22%2C%22lastName%22%3A%22Stein%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Florian%22%2C%22lastName%22%3A%22Koutny%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Johannes%22%2C%22lastName%22%3A%22Riedel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Natascha%22%2C%22lastName%22%3A%22D%5Cu00f6rr%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Klara%22%2C%22lastName%22%3A%22Meyer%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Marco%22%2C%22lastName%22%3A%22Colombo%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christian%20Heinz%22%2C%22lastName%22%3A%22Anderwald%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Matthias%22%2C%22lastName%22%3A%22Bl%5Cu00fcher%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Daniel%22%2C%22lastName%22%3A%22Weghuber%22%7D%5D%2C%22abstractNote%22%3A%22The%20single%20point%20insulin%20sensitivity%20estimator%20%28SPISE%29%20is%20a%20recently%20developed%20fasting%20index%20for%20insulin%20sensitivity%20based%20on%20triglycerides%2C%20high%20density%20lipoprotein%20cholesterol%2C%20and%20body%20mass%20index.%20SPISE%20has%20been%20validated%20in%20juveniles%20and%20adults%3B%20still%2C%20its%20role%20during%20childhood%20remains%20unclear.%20To%20evaluate%20the%20age-%20and%20sex-specific%20distribution%20of%20SPISE%2C%20its%20correlation%20with%20established%20fasting%20indexes%20and%20its%20application%20as%20a%20prognostic%20marker%20for%20future%20dysglycemia%20during%20childhood%20and%20adolescence%20were%20assessed.%20We%20performed%20linear%20modeling%20and%20correlation%20analyses%20on%20a%20cross-sectional%20cohort%20of%202107%20children%20and%20adolescents%20%28age%205%20to%2018.4%20years%29%20with%20overweight%20or%20obesity.%20Furthermore%2C%20survival%20analyses%20were%20conducted%20upon%20a%20longitudinal%20cohort%20of%20591%20children%20with%20overweight%5C%2Fobesity%20%281712%20observations%29%20with%20a%20maximum%20follow-up%20time%20of%20nearly%2020%20years%2C%20targeting%20prediabetes%5C%2Fdysglycemia%20as%20the%20end%20point.%20The%20SPISE%20index%20decreased%20significantly%20with%20age%20%28%5Cu22120.34%20units%20per%20year%2C%20p%20%3C%200.001%29%20among%20children%20and%20adolescents%20with%20overweight%20and%20obesity.%20Sex%20did%20not%20have%20an%20influence%20on%20SPISE.%20There%20was%20a%20modest%20correlation%20between%20SPISE%20and%20established%20fasting%20markers%20of%20insulin%20resistance%20%28R%20%3D%20%5Cu22120.49%20for%20HOMA-IR%2C%20R%20%3D%20%5Cu22120.55%20for%20QUICKI-IR%29.%20SPISE%20is%20a%20better%20prognostic%20marker%20for%20future%20dysglycemia%20%28hazard%20ratio%20%28HR%29%203.47%2C%2095%25%20confidence%20interval%20%28CI%29%201.60%5Cu20137.51%2C%20p%20%3C%200.01%29%20than%20HOMA-IR%20and%20QUICKI-IR%20%28HR%202.44%2C%2095%25%20CI%201.24%5Cu20134.81%2C%20p%20%3C%200.05%29.%20The%20SPISE%20index%20is%20a%20surrogate%20marker%20for%20insulin%20resistance%20predicting%20emerging%20dysglycemia%20in%20children%20with%20overweight%20or%20obesity%2C%20and%20could%2C%20therefore%2C%20be%20applied%20to%20pediatric%20cohorts%20that%20lack%20direct%20insulin%20assessment.%22%2C%22date%22%3A%222023%5C%2F1%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.3390%5C%2Fmetabo13010100%22%2C%22ISSN%22%3A%222218-1989%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.mdpi.com%5C%2F2218-1989%5C%2F13%5C%2F1%5C%2F100%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222024-03-28T15%3A36%3A49Z%22%7D%7D%2C%7B%22key%22%3A%2247FY4H7A%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Kiess%20et%20al.%22%2C%22parsedDate%22%3A%222022-02%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EKiess%2C%20Wieland%2C%20Anna%20S.%20Kirstein%2C%20Robert%20Stein%2C%20and%20Mandy%20Vogel.%20%26%23x201C%3BObesity%20After%20the%20Covid-19%20Pandemic%20and%20Beyond.%26%23x201D%3B%20%3Ci%3EJournal%20of%20Pediatric%20Endocrinology%20and%20Metabolism%3C%5C%2Fi%3E%2035%2C%20no.%202%20%28February%202022%29%3A%20135%26%23×2013%3B38.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1515%5C%2Fjpem-2022-2135%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1515%5C%2Fjpem-2022-2135%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Obesity%20After%20the%20Covid-19%20Pandemic%20and%20Beyond%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anna%20S.%22%2C%22lastName%22%3A%22Kirstein%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Robert%22%2C%22lastName%22%3A%22Stein%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%5D%2C%22abstractNote%22%3A%22Article%20Obesity%20after%20the%20Covid-19%20pandemic%20and%20beyond%20was%20published%20on%20February%201%2C%202022%20in%20the%20journal%20Journal%20of%20Pediatric%20Endocrinology%20and%20Metabolism%20%28volume%2035%2C%20issue%202%29.%22%2C%22date%22%3A%222022-02%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1515%5C%2Fjpem-2022-2135%22%2C%22ISSN%22%3A%222191-0251%22%2C%22url%22%3A%22http%3A%5C%2F%5C%2Fwww.degruyter.com%5C%2Fdocument%5C%2Fdoi%5C%2F10.1515%5C%2Fjpem-2022-2135%5C%2Fhtml%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-24T09%3A07%3A23Z%22%7D%7D%2C%7B%22key%22%3A%22BKYSLV9N%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Vogel%20et%20al.%22%2C%22parsedDate%22%3A%222022-01%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EVogel%2C%20Mandy%2C%20Mandy%20Geserick%2C%20Ruth%20Gausche%2C%20Christoph%20Beger%2C%20Tanja%20Poulain%2C%20Christof%20Meigen%2C%20Antje%20K%26%23xF6%3Brner%2C%20Eberhard%20Keller%2C%20Wieland%20Kiess%2C%20and%20Roland%20Pf%26%23xE4%3Bffle.%20%26%23x201C%3BAge-%20and%20Weight%20Group-Specific%20Weight%20Gain%20Patterns%20in%20Children%20and%20Adolescents%20During%20the%2015%20Years%20Before%20and%20During%20the%20Covid-19%20Pandemic.%26%23x201D%3B%20%3Ci%3EInternational%20Journal%20of%20Obesity%20%282005%29%3C%5C%2Fi%3E%2046%2C%20no.%201%20%28January%202022%29%3A%20144%26%23×2013%3B52.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1038%5C%2Fs41366-021-00968-2%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1038%5C%2Fs41366-021-00968-2%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Age-%20and%20Weight%20Group-Specific%20Weight%20Gain%20Patterns%20in%20Children%20and%20Adolescents%20During%20the%2015%20Years%20Before%20and%20During%20the%20Covid-19%20Pandemic%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Geserick%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ruth%22%2C%22lastName%22%3A%22Gausche%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christoph%22%2C%22lastName%22%3A%22Beger%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christof%22%2C%22lastName%22%3A%22Meigen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Eberhard%22%2C%22lastName%22%3A%22Keller%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Roland%22%2C%22lastName%22%3A%22Pf%5Cu00e4ffle%22%7D%5D%2C%22abstractNote%22%3A%22BACKGROUND%5C%2FOBJECTIVES%3A%20There%20is%20a%20concern%20that%20measures%20aiming%20to%20limit%20a%20further%20spread%20of%20COVID-19%2C%20e.g.%2C%20school%20closures%20and%20social%20distancing%2C%20cause%20an%20aggravation%20of%20the%20childhood%20obesity%20epidemic.%20Therefore%2C%20we%20compared%20BMI%20trends%20during%20the%2015%20years%20before%20and%20during%20the%20COVID-19%20pandemic.%5CnSUBJECTS%5C%2FMETHODS%3A%20To%20assess%20the%20change%20in%20weight%20dynamics%20during%20the%20first%20months%20of%20COVID-19%2C%20we%20compared%20the%20trends%20of%203-month%20change%20in%20BMI-SDS%20%28%5Cu0394BMI-SDS%29%20and%20the%20proportions%20of%20children%20showing%20a%20high%20positive%20%28HPC%29%20or%20high%20negative%20%28HNC%29%20weight%20change%20between%202005%20and%202019%20and%20the%20respective%20changes%20from%202019%20%28pre-pandemic%29%20to%202020%20%28after%20the%20onset%20of%20anti-pandemic%20measures%29%20in%20more%20than%20150%2C000%20children%20%289689%20during%20the%20pandemic%20period%29.%20The%20period%20of%203%20months%20corresponds%20approximately%20to%20the%20first%20lockdown%20period%20in%20Germany.%5CnRESULTS%3A%20During%20the%20COVID-19%20pandemic%2C%20we%20found%20a%20substantial%20weight%20gain%20across%20all%20weight%20and%20age%20groups%2C%20reflected%20by%20an%20increase%20in%20the%203-month%20change%20in%20BMI-SDS%20%28%5Cu03b2%5Cu2009%3D%5Cu20090.05%2C%20p%5Cu2009%3C%5Cu20090.001%29%2C%20an%20increase%20in%20the%20proportion%20of%20children%20showing%20HPC%20%28OR%5Cu2009%3D%5Cu20091.4%2C%20p%5Cu2009%3C%5Cu20090.001%29%2C%20and%20a%20decrease%20in%20the%20proportion%20of%20children%20showing%20HNC%20%28OR%5Cu2009%3D%5Cu20090.7%2C%20p%5Cu2009%3C%5Cu20090.001%29.%20Besides%2C%20we%20found%20the%20same%20trends%20since%202005%20on%20a%20low%20but%20stable%20level%20with%20a%20yearly%20increase%20of%20%5Cu0394BMI-SDS%20by%20%5Cu03b2%5Cu2009%3D%5Cu20090.001%20%28p%5Cu2009%3C%5Cu20090.001%29%2C%20the%20odds%20of%20HPC%20increased%20by%20ORhigh_pos%5Cu2009%3D%5Cu20091.01%20%28p%5Cu2009%3C%5Cu20090.001%29%2C%20and%20the%20odds%20of%20HNC%20decreased%20by%20ORhigh_neg%5Cu2009%3D%5Cu20090.99%20%28p%5Cu2009%3C%5Cu20090.001%29.%20These%20rather%20small%20effects%20accumulated%20to%20%5Cu03b2%5Cu2009%3D%5Cu20090.02%2C%20ORhigh_pos%5Cu2009%3D%5Cu20091.14%2C%20and%20ORhigh_pos%5Cu2009%3D%5Cu20090.85%20over%20the%20whole%20period%202005-2019.%20Alarmingly%2C%20both%20the%20long-term%20and%20the%20short-term%20effects%20were%20most%20pronounced%20in%20the%20obese%20subgroup.%5CnCONCLUSIONS%3A%20There%20are%20positive%20dynamics%20in%20different%20measures%20of%20weight%20change%2C%20indicating%20a%20positive%20trend%20in%20weight%20gain%20patterns%2C%20especially%20within%20the%20group%20of%20children%20with%20obesity.%20These%20dynamics%20are%20likely%20to%20be%20escalated%20by%20COVID-19-related%20measures.%20Thus%2C%20they%20may%20lead%20to%20a%20significant%20further%20aggravation%20of%20the%20childhood%20obesity%20pandemic.%22%2C%22date%22%3A%222022-01%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1038%5C%2Fs41366-021-00968-2%22%2C%22ISSN%22%3A%221476-5497%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-12-30T09%3A12%3A08Z%22%7D%7D%2C%7B%22key%22%3A%22RHU89NAH%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Bohn%20et%20al.%22%2C%22parsedDate%22%3A%222022%22%2C%22numChildren%22%3A2%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EBohn%2C%20Claudia%2C%20Mandy%20Vogel%2C%20Tanja%20Poulain%2C%20Andreas%20Hiemisch%2C%20Wieland%20Kiess%2C%20and%20Antje%20K%26%23xF6%3Brner.%20%26%23x201C%3BHaving%20Siblings%20Promotes%20a%20More%20Healthy%20Weight%20Status-Whereas%20Only%20Children%20Are%20at%20Greater%20Risk%20for%20Higher%20BMI%20in%20Later%20Childhood.%26%23x201D%3B%20%3Ci%3EPloS%20One%3C%5C%2Fi%3E%2017%2C%20no.%207%20%282022%29%3A%20e0271676.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1371%5C%2Fjournal.pone.0271676%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1371%5C%2Fjournal.pone.0271676%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Having%20siblings%20promotes%20a%20more%20healthy%20weight%20status-Whereas%20only%20children%20are%20at%20greater%20risk%20for%20higher%20BMI%20in%20later%20childhood%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Claudia%22%2C%22lastName%22%3A%22Bohn%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andreas%22%2C%22lastName%22%3A%22Hiemisch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%5D%2C%22abstractNote%22%3A%22BACKGROUND%3A%20Birth%20order%20and%20having%20at%20least%20one%20sibling%20are%20known%20to%20be%20associated%20with%20an%20increased%20risk%20for%20development%20of%20overweight.%20However%2C%20there%20are%20no%20studies%20assessing%20pre-%20and%20postnatal%20factors%20for%20developing%20overweight%20within%20families.%20Therefore%2C%20the%20present%20study%20aimed%20to%20analyse%20the%20association%20of%20the%20mother%27s%20weight%20gain%20during%20pregnancy%2C%20prepregnancy%20BMI%2C%20mother%27s%20age%20at%20birth%2C%20breastfeeding%2C%20age%20gap%20between%20siblings%2C%20and%20physical%20activity%20together%20with%20sibling-related%20characteristics%20on%20the%20development%20of%20overweight%20in%20children%20and%20adolescents.%5CnMETHODS%3A%20Data%20were%20obtained%20from%20the%20longitudinal%20LIFE%20Child%20cohort.%20The%20study%20sample%20included%20n%20%3D%201932%20children%2C%20stratified%20into%20first-born%20%28n%20%3D%20578%29%2C%20second-born%20%28n%20%3D%20608%29%2C%20third-or-later-born%20single-born%20siblings%20%28n%20%3D%20162%29%2C%20only%20children%20%28n%20%3D%20526%29%2C%20and%20twin%20children%20%28n%20%3D%2058%29.%20Children%20with%20chronic%20or%20syndromic%20diseases%2C%20born%20prematurely%20or%20from%20mothers%20with%20gestational%20diabetes%20were%20excluded.%20Data%20were%20adjusted%20for%20multiple%20children%20per%20family%20using%20mixed%20models.%20Pregnancy%20weight%20gain%2C%20prepregnancy%20BMI%20and%20mother%27s%20age%20were%20considered%20prenatal%20co-variates.%20Postnatal%20factors%20included%20the%20duration%20of%20breastfeeding%20and%20the%20children%27s%20physical%20activity%20level.%5CnRESULTS%3A%20Particularly%20until%20the%20onset%20of%20puberty%2C%20the%20BMI-SDS%20differed%20between%20single-born%20siblings%2C%20only%20children%20and%20twins%2C%20and%20increased%20with%20birth%20order.%20Compared%20to%20children%20with%20siblings%2C%20only%20children%20exhibited%20a%20strong%20increase%20in%20BMI-SDS%20starting%20at%20age%20nine.%20A%20higher%20age%20gap%20between%20siblings%20was%20associated%20with%20a%20higher%20BMI-SDS%20in%20second-%20and%20third-or-later-born%20children.%20Single-born%20siblings%20had%20the%20highest%20rate%20and%20duration%20of%20breastfeeding.%20Physical%20activity%20was%20highest%20in%20twins%20and%20third-or-later-born%20children%20and%20lowest%20in%20only%20children.%20In%20a%20multivariate%20model%2C%20being%20an%20only%20child%20showed%20a%20highly%20significant%20association%20with%20BMI-SDS.%5CnCONCLUSION%3A%20The%20present%20study%20demonstrated%20that%20siblings%20had%20a%20lower%20BMI-SDS%20than%20only%20children%20did.%20For%20single-born%20siblings%2C%20the%20association%20between%20birth%20order%20and%20increased%20BMI-SDS%20seemed%20to%20persist%20only%20up%20to%2011%20years%20of%20age.%22%2C%22date%22%3A%222022%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1371%5C%2Fjournal.pone.0271676%22%2C%22ISSN%22%3A%221932-6203%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-23T10%3A29%3A48Z%22%7D%7D%2C%7B%22key%22%3A%22ETFXTELD%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Vogel%20et%20al.%22%2C%22parsedDate%22%3A%222022%22%2C%22numChildren%22%3A2%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EVogel%2C%20Mandy%2C%20Mandy%20Geserick%2C%20Ruth%20Gausche%2C%20Christoph%20Beger%2C%20Tanja%20Poulain%2C%20Christof%20Meigen%2C%20Antje%20K%26%23xF6%3Brner%2C%20et%20al.%20%26%23x201C%3BGewichtszunahme%20Bei%20Kindern%20Und%20Jugendlichen%20W%26%23xE4%3Bhrend%20Der%20Covid-19-Pandemie.%26%23x201D%3B%20%3Ci%3EKinder-%20Und%20Jugendmedizin%3C%5C%2Fi%3E%2022%2C%20no.%202%20%282022%29%3A%20112%26%23×2013%3B17.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1055%5C%2Fa-1732-1623%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1055%5C%2Fa-1732-1623%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Gewichtszunahme%20bei%20Kindern%20und%20Jugendlichen%20w%5Cu00e4hrend%20der%20Covid-19-Pandemie%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Geserick%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ruth%22%2C%22lastName%22%3A%22Gausche%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christoph%22%2C%22lastName%22%3A%22Beger%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christof%22%2C%22lastName%22%3A%22Meigen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Carolin%22%2C%22lastName%22%3A%22Sobek%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Eberhard%22%2C%22lastName%22%3A%22Keller%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Roland%22%2C%22lastName%22%3A%22Pf%5Cu00e4ffle%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%5D%2C%22abstractNote%22%3A%22Es%20wurde%20viel%20dar%5Cu00fcber%20spekuliert%2C%20ob%20durch%20Schulschlie%5Cu00dfungen%2C%20eingeschr%5Cu00e4nkte%20soziale%20Kontakte%20und%20den%20Wegfall%20sportlicher%20Aktivit%5Cu00e4ten%20w%5Cu00e4hrend%20der%20Covid-19-Pandemie%20die%20Adipositasepidemie%20im%20Kindesalter%20verst%5Cu00e4rkt%20werden%20w%5Cu00fcrde.%20Deshalb%20haben%20wir%20die%20BMI-Verl%5Cu00e4ufe%20w%5Cu00e4hrend%20der%2015%20Jahre%20vor%20und%20w%5Cu00e4hrend%20der%20Covid-19-Pandemie%20untersucht.%20Der%20Trend%20der%20BMI-Ver%5Cu00e4nderungen%20%28als%20delta-BMI-SDS%29%20und%20die%20Anteile%20der%20Kinder%2C%20die%20Gewicht%20zunahmen%20bzw.%20verloren%2C%20zwischen%202005%20und%202019%20sowie%20entsprechend%20Daten%20von%202019%20vor%20der%20Pandemie%20und%20von%202020%20nach%20dem%20Einsetzen%20der%20ersten%20Pandemiema%5Cu00dfnahmen%20wurden%20bei%20mehr%20als%20150%20000%20Kindern%20%28ca.%2010%20000%20in%20der%20pandemischen%20Phase%29%20verglichen.%20W%5Cu00e4hrend%20der%20Covid-19-Pandemie%20fand%20sich%20eine%20substanzielle%20Gewichtszunahme%20%5Cu00fcber%20alle%20Gewichtsklassen%20und%20Altersstufen%20hinweg.%20Die%20%5Cu00c4nderung%20des%20mittleren%20BMI-SDS%20war%20wesentlich%20h%5Cu00f6her%20als%20in%20den%20Jahren%20zuvor.%20Ebenso%20stieg%20der%20Anteil%20der%20Kinder%2C%20die%20Gewicht%20zunahmen.%20Der%20Anteil%20der%20Kinder%2C%20die%20Gewicht%20%5Cu00fcber%20den%20Zeitraum%20verloren%2C%20nahm%20hingegen%20ab.%20Au%5Cu00dferdem%20fanden%20wir%20%5Cu00e4hnliche%20Trends%2C%20der%20zwar%20auf%20eine%20wesentlich%20schw%5Cu00e4chere%2C%20aber%20doch%20stetige%20Gewichtszunahme%20hinweisen%2C%20bereits%20seit%202005.%20Es%20ist%20alarmierend%2C%20dass%20sowohl%20der%20langfristige%20Trend%20als%20auch%20die%20kurzfristigen%2C%20pandemie-bezogenen%20Effekte%20bei%20Kindern%2C%20die%20bereits%20%5Cu00fcbergewichtig%20oder%20adip%5Cu00f6s%20waren%2C%20am%20gr%5Cu00f6%5Cu00dften%20waren.%5Cn%5CnDie%20Trends%2C%20die%20wir%20in%20mehreren%20Parametern%20der%20Gewichtsver%5Cu00e4nderung%20%5Cu00fcber%20einen%20Zeitraum%20von%20mehr%20als%2015%20Jahren%20beobachten%20konnten%2C%20weisen%20auf%20eine%20Zunahme%20des%20BMI-SDS.%20Besonders%20bei%20adip%5Cu00f6sen%20Kindern%20ist%20diese%20Dynamik%20ausgepr%5Cu00e4gt.%20Covid-19-bezogene%20Ma%5Cu00dfnahmen%20verst%5Cu00e4rken%20die%20Effekte%20und%20k%5Cu00f6nnten%20damit%20die%20Adipositasepidemie%20im%20Kindesalter%20weiter%20eskalieren.%22%2C%22date%22%3A%222022%22%2C%22language%22%3A%22%22%2C%22DOI%22%3A%2210.1055%5C%2Fa-1732-1623%22%2C%22ISSN%22%3A%22%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-24T13%3A35%3A12Z%22%7D%7D%2C%7B%22key%22%3A%22H3XTUW3C%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Eichler%20et%20al.%22%2C%22parsedDate%22%3A%222021-09%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EEichler%2C%20Janina%2C%20Ricarda%20Schmidt%2C%20Tanja%20Poulain%2C%20Andreas%20Hiemisch%2C%20Wieland%20Kiess%2C%20and%20Anja%20Hilbert.%20%26%23x201C%3BMaternal%20Depressive%20Symptoms%20and%20Stress%20During%20Pregnancy%20as%20Predictors%20of%20Gestational%20Age%20at%20Birth%20and%20Standardized%20Body%20Mass%20Index%20from%20Birth%20up%20to%202%20Years%20of%20Age.%26%23x201D%3B%20%3Ci%3EBMC%20Pregnancy%20and%20Childbirth%3C%5C%2Fi%3E%2021%2C%20no.%201%20%28September%202021%29%3A%20635.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs12884-021-04111-x%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs12884-021-04111-x%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Maternal%20Depressive%20Symptoms%20and%20Stress%20During%20Pregnancy%20as%20Predictors%20of%20Gestational%20Age%20at%20Birth%20and%20Standardized%20Body%20Mass%20Index%20from%20Birth%20up%20to%202%20Years%20of%20Age%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Janina%22%2C%22lastName%22%3A%22Eichler%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ricarda%22%2C%22lastName%22%3A%22Schmidt%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andreas%22%2C%22lastName%22%3A%22Hiemisch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anja%22%2C%22lastName%22%3A%22Hilbert%22%7D%5D%2C%22abstractNote%22%3A%22BACKGROUND%3A%20While%20depressive%20symptoms%20and%20stress%20during%20pregnancy%20are%20known%20to%20affect%20gestational%20age%20and%20weight%20at%20birth%2C%20evidence%20on%20their%20impact%20on%20child%20anthropometric%20development%20in%20the%20long%20term%20remains%20limited%2C%20showing%20inconsistent%20effects.%20Importantly%2C%20previous%20research%20indicated%20a%20substantially%20stronger%20impact%20of%20categorically%20rather%20than%20dimensionally%20assessed%20mental%20health%20problems%20on%20birth%20outcomes%20and%20child%20development.%5CnMETHODS%3A%20The%20Patient%20Health%20Questionnaire%20was%20used%20to%20assess%20depressive%20symptoms%20and%20stress%20during%20the%202nd%20trimester%20of%20pregnancy%20dimensionally%20and%20categorically%2C%20with%20scores%20%5Cu226510%20indicating%20clinical%20significance.%20Gestational%20age%20at%20birth%20and%20BMI-SDS%20from%20birth%20up%20to%202%5Cu2009years%20of%20age%20were%20examined%20as%20dependent%20variables.%20Structural%20equation%20modeling%20was%20used%20to%20examine%20the%20prediction%20of%20birth%20outcomes%20and%20child%20anthropometry%20by%20mental%20health%20problems%20while%20controlling%20for%20multiple%20maternal%20and%20child%20characteristics%20in%20322%20mother-child%20dyads.%5CnRESULTS%3A%20Dimensionally%20assessed%20mental%20health%20problems%20did%20not%20significantly%20predict%20birth%20outcomes.%20While%20categorical%20depressive%20symptoms%20significantly%20predicted%20a%20higher%20child%20BMI-SDS%2C%20categorical%20stress%20significantly%20predicted%20a%20lower%20gestational%20age%20at%20birth.%20Neither%20categorical%20nor%20dimensional%20mental%20health%20problems%20significantly%20predicted%20child%20BMI-SDS%20at%206%2C%2012%2C%20and%2024%5Cu2009months%20postpartum.%5CnCONCLUSIONS%3A%20Depressive%20symptoms%20and%20stress%20during%20pregnancy%20seem%20to%20differentially%20affect%20birth%20outcomes%2C%20and%20only%20if%20clinically%20relevant.%20The%20results%20implicate%20the%20importance%20to%20timely%20treat%20pregnant%20women%20that%20are%20greatly%20affected%20by%20mental%20health%20problems%20to%20potentially%20reduce%20adverse%20birth%20outcomes.%22%2C%22date%22%3A%222021-09%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1186%5C%2Fs12884-021-04111-x%22%2C%22ISSN%22%3A%221471-2393%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Forgid.org%5C%2F10.1186%5C%2Fs12884-021-04111-x%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-23T13%3A48%3A41Z%22%7D%7D%2C%7B%22key%22%3A%22F8U2593U%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Kiess%20and%20Haeusler%22%2C%22parsedDate%22%3A%222021-09%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EKiess%2C%20Wieland%2C%20and%20Gabriele%20Haeusler.%20%26%23x201C%3BEndocrine-Disrupting%20Chemicals.%26%23x201D%3B%20%3Ci%3EBest%20Practice%20%26amp%3B%20Research.%20Clinical%20Endocrinology%20%26amp%3B%20Metabolism%3C%5C%2Fi%3E%2035%2C%20no.%205%20%28September%202021%29%3A%20101566.%20%3Ca%20class%3D%27zp-ItemURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.beem.2021.101566%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.beem.2021.101566%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Endocrine-Disrupting%20Chemicals%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Gabriele%22%2C%22lastName%22%3A%22Haeusler%22%7D%5D%2C%22abstractNote%22%3A%22%22%2C%22date%22%3A%222021-09%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1016%5C%2Fj.beem.2021.101566%22%2C%22ISSN%22%3A%221878-1594%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.beem.2021.101566%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-24T09%3A06%3A44Z%22%7D%7D%2C%7B%22key%22%3A%22U9X95DPA%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Kempf%20et%20al.%22%2C%22parsedDate%22%3A%222021-06%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EKempf%2C%20Elena%2C%20Mandy%20Vogel%2C%20Tim%20Vogel%2C%20J%26%23xFC%3Brgen%20Kratzsch%2C%20Kathrin%20Landgraf%2C%20Andreas%20K%26%23xFC%3Bhnapfel%2C%20Ruth%20Gausche%2C%20et%20al.%20%26%23x201C%3BDynamic%20Alterations%20in%20Linear%20Growth%20and%20Endocrine%20Parameters%20in%20Children%20with%20Obesity%20and%20Height%20Reference%20Values.%26%23x201D%3B%20%3Ci%3EEClinicalMedicine%3C%5C%2Fi%3E%2037%20%28June%202021%29%3A%20100977.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.eclinm.2021.100977%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.eclinm.2021.100977%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Dynamic%20Alterations%20in%20Linear%20Growth%20and%20Endocrine%20Parameters%20in%20Children%20with%20Obesity%20and%20Height%20Reference%20Values%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Elena%22%2C%22lastName%22%3A%22Kempf%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tim%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J%5Cu00fcrgen%22%2C%22lastName%22%3A%22Kratzsch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Kathrin%22%2C%22lastName%22%3A%22Landgraf%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andreas%22%2C%22lastName%22%3A%22K%5Cu00fchnapfel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ruth%22%2C%22lastName%22%3A%22Gausche%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Daniel%22%2C%22lastName%22%3A%22Gr%5Cu00e4fe%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Elena%22%2C%22lastName%22%3A%22Sergeyev%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Roland%22%2C%22lastName%22%3A%22Pf%5Cu00e4ffle%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Juraj%22%2C%22lastName%22%3A%22Stanik%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%5D%2C%22abstractNote%22%3A%22Background%5CnObesity%20can%20affect%20linear%20growth%20of%20children%20but%20there%20is%20uncertainty%20regarding%20the%20dynamics%20and%20potential%20causes.%5CnMethods%5CnIn%20the%20population-based%20LIFE%20Child%20and%20the%20obesity-enriched%20Leipzig%20Obesity%20Childhood%20cohorts%20%288%2C629%20children%2C%2037%2C493%20measurements%29%2C%20recruited%20from%201999%20to%202018%20in%20Germany%2C%20we%20compared%20height%2C%20growth%2C%20and%20endocrine%20parameters%20between%20normal-weight%20and%20children%20with%20obesity%20%280%5Cu201320%20years%29.%20Derived%20from%20the%20independent%20German%20CrescNet%20registry%20%2812%2C703%20children%29%20we%20generated%20height%20reference%20values%20specific%20for%20children%20with%20obesity%20%28data%20collected%20from%201999%20to%202020%29.%5CnFindings%5CnChildren%20with%20obesity%20were%20significantly%20taller%20than%20normal-weight%20peers%2C%20differing%20at%20maximum%20by%207%5Cu00b76%5Cu00a0cm%20%281%5Cu00b74%20height%2C%20standard%20deviation%20scores%20or%20SDS%29%20at%20age%206%5Cu20138%20years.%20Already%20at%20birth%2C%20children%20with%20obesity%20were%20slightly%20taller%20and%20thereafter%20had%20increased%20growth%20velocities%20by%20up%20to%201%5Cu00b72%5Cu00a0cm%5C%2Fyear.%20This%20growth%20acceleration%20was%20unrelated%20to%20parental%20height%2C%20but%20was%20accompanied%20by%20increased%20levels%20of%20insulin-like%20growth%20factor-1%20%28IGF-1%29%2C%20insulin%20and%20leptin.%20During%20puberty%2C%20children%20with%20obesity%20showed%20a%20catch-down%20in%20height%20SDS.%20The%20reduction%20in%20pubertal%20growth%20velocity%20by%20up%20to%2025%25%20coincided%20with%20a%20decrease%20in%20levels%20of%20IGF-1%20%28by%2017%25%29%20and%20testosterone%20%28by%2062%25%29%20in%20boys%20and%20estradiol%20%28by%2037%25%29%20in%20girls.%20We%20confirmed%20these%20alterations%20in%20growth%20in%20the%20independent%20CrescNet%20cohort%20and%20furthermore%20provide%20height%20reference%20values%20for%20children%20with%20obesity%20for%20open%20access.%5CnInterpretation%5CnDynamics%20of%20linear%20growth%20are%20altered%20distinctively%20in%20different%20developmental%20phases%20in%20children%20with%20obesity.%20Early%20emergence%20before%20other%20profound%20comorbidities%20implies%20predisposition%2C%20environmental%2C%20and%5C%2For%20endocrine%20factors%20affecting%20growth%20in%20early%20life.%20Height%20reference%20values%20for%20children%20with%20obesity%20may%20enhance%20the%20precision%20of%20clinical%20health%20surveillance.%5CnFunding%5CnGerman%20Research%20Foundation%2C%20German%20Diabetes%20Association%2C%20EU%2C%20ESF%2C%20ERDF%2C%20State%20of%20Saxony%2C%20ESPE%2C%20Hexal%2C%20Novo%20Nordisk%2C%20Pfizer%20Pharma.%22%2C%22date%22%3A%22June%2C%202021%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1016%5C%2Fj.eclinm.2021.100977%22%2C%22ISSN%22%3A%222589-5370%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.sciencedirect.com%5C%2Fscience%5C%2Farticle%5C%2Fpii%5C%2FS2589537021002571%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-12-31T14%3A24%3A55Z%22%7D%7D%2C%7B%22key%22%3A%22LTS23877%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Bohn%20et%20al.%22%2C%22parsedDate%22%3A%222021%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EBohn%2C%20Claudia%2C%20Mandy%20Vogel%2C%20Tanja%20Poulain%2C%20Ulrike%20Spielau%2C%20Cornelia%20Hilbert%2C%20Wieland%20Kiess%2C%20and%20Antje%20K%26%23xF6%3Brner.%20%26%23x201C%3BBirth%20Weight%20Increases%20with%20Birth%20Order%20Despite%20Decreasing%20Maternal%20Pregnancy%20Weight%20Gain.%26%23x201D%3B%20%3Ci%3EActa%20Paediatrica%3C%5C%2Fi%3E%20110%2C%20no.%204%20%282021%29%3A%201218%26%23×2013%3B24.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fapa.15598%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fapa.15598%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Birth%20Weight%20Increases%20with%20Birth%20Order%20Despite%20Decreasing%20Maternal%20Pregnancy%20Weight%20Gain%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Claudia%22%2C%22lastName%22%3A%22Bohn%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ulrike%22%2C%22lastName%22%3A%22Spielau%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Cornelia%22%2C%22lastName%22%3A%22Hilbert%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%5D%2C%22abstractNote%22%3A%22Aim%20We%20investigated%20whether%20birth%20order%20is%20an%20influencing%20factor%20for%20birth%20weight%20independent%20from%20maternal%20factors.%20Methods%20Data%20were%20obtained%20from%20the%20longitudinal%20cohort%20study%20LIFE%20Child%20and%20included%201864%20children%2C%20of%20which%20526%20were%20only%20children.%20The%201338%20siblings%20were%20ranked%20into%20first-borns%20%28n%20%3D%20570%29%2C%20second-borns%20%28n%20%3D%20606%29%20and%20third-or-later-borns%20%28n%20%3D%20162%29.%20Children%20born%20prematurely%2C%20suffering%20from%20chronic%20or%20syndromic%20diseases%2C%20were%20excluded.%20We%20performed%20intra-family%20comparisons%20to%20reduce%20bias%20and%20assessed%20the%20impact%20of%20perinatal%20parameters%2C%20such%20as%20birth%20order%20on%20birth%20weight%2C%20using%20mixed%20models.%20Results%20Birth%20weight%20increased%20with%20birth%20order.%20In%20univariate%20analyses%2C%20birth%20order%20had%20a%20significant%20effect%20on%20birth%20weight-SDS%20with%20second-borns%20having%200.29%20SDS%20%28app.%20130%20g%29%20and%20third-borns%200.40%20SDS%20%28app.%20180%20g%29%20higher%20values%20than%20first-borns%20%28P%20%3C%20.001%29.%20Maternal%20pregnancy%20weight%20gain%20was%20associated%20with%20higher%20birth%20weight-SDS%20%28P%20%3C%20.01%29%20in%20univariate%20analysis%2C%20though%20maternal%20pregnancy%20weight%20gain%20was%20lower%20for%20higher%20birth%20orders.%20Multivariate%20analyses%20revealed%20that%20being%20a%20second%20or%20third-or-later-born%20child%20had%20a%20stronger%20impact%20on%20birth%20weight%20than%20all%20maternal%20factors.%20Conclusion%20Birth%20order%20must%20be%20considered%20a%20potential%20risk%20factor%20for%20higher%20birth%20weight.%20Maternal%20pregnancy%20weight%20gain%20is%20not%20the%20driving%20factor%20for%20higher%20birth%20weight%20in%20siblings.%22%2C%22date%22%3A%222021-21%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1111%5C%2Fapa.15598%22%2C%22ISSN%22%3A%221651-2227%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fonlinelibrary.wiley.com%5C%2Fdoi%5C%2Fabs%5C%2F10.1111%5C%2Fapa.15598%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-07T07%3A01%3A54Z%22%7D%7D%2C%7B%22key%22%3A%22W3SPDAAZ%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Vogelezang%20et%20al.%22%2C%22parsedDate%22%3A%222020-10%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EVogelezang%2C%20Suzanne%2C%20Jonathan%20P.%20Bradfield%2C%20Tarunveer%20S.%20Ahluwalia%2C%20John%20A.%20Curtin%2C%20Timo%20A.%20Lakka%2C%20Niels%20Grarup%2C%20Markus%20Scholz%2C%20et%20al.%20%26%23x201C%3BNovel%20Loci%20for%20Childhood%20Body%20Mass%20Index%20and%20Shared%20Heritability%20with%20Adult%20Cardiometabolic%20Traits.%26%23x201D%3B%20%3Ci%3EPLOS%20Genetics%3C%5C%2Fi%3E%2016%2C%20no.%2010%20%28October%202020%29%3A%20e1008718.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1371%5C%2Fjournal.pgen.1008718%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1371%5C%2Fjournal.pgen.1008718%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Novel%20Loci%20for%20Childhood%20Body%20Mass%20Index%20and%20Shared%20Heritability%20with%20Adult%20Cardiometabolic%20Traits%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Suzanne%22%2C%22lastName%22%3A%22Vogelezang%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jonathan%20P.%22%2C%22lastName%22%3A%22Bradfield%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tarunveer%20S.%22%2C%22lastName%22%3A%22Ahluwalia%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22John%20A.%22%2C%22lastName%22%3A%22Curtin%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Timo%20A.%22%2C%22lastName%22%3A%22Lakka%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Niels%22%2C%22lastName%22%3A%22Grarup%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Markus%22%2C%22lastName%22%3A%22Scholz%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Peter%20J.%20van%20der%22%2C%22lastName%22%3A%22Most%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Claire%22%2C%22lastName%22%3A%22Monnereau%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Evie%22%2C%22lastName%22%3A%22Stergiakouli%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anni%22%2C%22lastName%22%3A%22Heiskala%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Momoko%22%2C%22lastName%22%3A%22Horikoshi%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Iryna%20O.%22%2C%22lastName%22%3A%22Fedko%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Natalia%22%2C%22lastName%22%3A%22Vilor-Tejedor%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Diana%20L.%22%2C%22lastName%22%3A%22Cousminer%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Marie%22%2C%22lastName%22%3A%22Standl%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Carol%20A.%22%2C%22lastName%22%3A%22Wang%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jorma%22%2C%22lastName%22%3A%22Viikari%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Frank%22%2C%22lastName%22%3A%22Geller%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Carmen%22%2C%22lastName%22%3A%22%5Cu00cd%5Cu00f1iguez%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Niina%22%2C%22lastName%22%3A%22Pitk%5Cu00e4nen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Alessandra%22%2C%22lastName%22%3A%22Chesi%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jonas%22%2C%22lastName%22%3A%22Bacelis%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Loic%22%2C%22lastName%22%3A%22Yengo%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Maties%22%2C%22lastName%22%3A%22Torrent%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ioanna%22%2C%22lastName%22%3A%22Ntalla%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22%5Cu00d8yvind%22%2C%22lastName%22%3A%22Helgeland%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Saskia%22%2C%22lastName%22%3A%22Selzam%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Judith%20M.%22%2C%22lastName%22%3A%22Vonk%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mohammed%20H.%22%2C%22lastName%22%3A%22Zafarmand%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Barbara%22%2C%22lastName%22%3A%22Heude%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ismaa%20Sadaf%22%2C%22lastName%22%3A%22Farooqi%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Akram%22%2C%22lastName%22%3A%22Alyass%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Robin%20N.%22%2C%22lastName%22%3A%22Beaumont%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christian%20T.%22%2C%22lastName%22%3A%22Have%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Peter%22%2C%22lastName%22%3A%22Rzehak%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jose%20Ramon%22%2C%22lastName%22%3A%22Bilbao%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Theresia%20M.%22%2C%22lastName%22%3A%22Schnurr%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22In%5Cu00eas%22%2C%22lastName%22%3A%22Barroso%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Klaus%22%2C%22lastName%22%3A%22B%5Cu00f8nnelykke%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Lawrence%20J.%22%2C%22lastName%22%3A%22Beilin%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Lisbeth%22%2C%22lastName%22%3A%22Carstensen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Marie-Aline%22%2C%22lastName%22%3A%22Charles%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Bo%22%2C%22lastName%22%3A%22Chawes%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Karine%22%2C%22lastName%22%3A%22Cl%5Cu00e9ment%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ricardo%22%2C%22lastName%22%3A%22Closa-Monasterolo%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Adnan%22%2C%22lastName%22%3A%22Custovic%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Johan%20G.%22%2C%22lastName%22%3A%22Eriksson%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Joaquin%22%2C%22lastName%22%3A%22Escribano%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Maria%22%2C%22lastName%22%3A%22Groen-Blokhuis%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Veit%22%2C%22lastName%22%3A%22Grote%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Dariusz%22%2C%22lastName%22%3A%22Gruszfeld%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Hakon%22%2C%22lastName%22%3A%22Hakonarson%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Torben%22%2C%22lastName%22%3A%22Hansen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andrew%20T.%22%2C%22lastName%22%3A%22Hattersley%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mette%22%2C%22lastName%22%3A%22Hollensted%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jouke-Jan%22%2C%22lastName%22%3A%22Hottenga%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Elina%22%2C%22lastName%22%3A%22Hypp%5Cu00f6nen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Stefan%22%2C%22lastName%22%3A%22Johansson%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Raimo%22%2C%22lastName%22%3A%22Joro%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mika%22%2C%22lastName%22%3A%22K%5Cu00e4h%5Cu00f6nen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ville%22%2C%22lastName%22%3A%22Karhunen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Bridget%20A.%22%2C%22lastName%22%3A%22Knight%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Berthold%22%2C%22lastName%22%3A%22Koletzko%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andreas%22%2C%22lastName%22%3A%22K%5Cu00fchnapfel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Kathrin%22%2C%22lastName%22%3A%22Landgraf%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jean-Paul%22%2C%22lastName%22%3A%22Langhendries%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Terho%22%2C%22lastName%22%3A%22Lehtim%5Cu00e4ki%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jaakko%20T.%22%2C%22lastName%22%3A%22Leinonen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Aihuali%22%2C%22lastName%22%3A%22Li%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Virpi%22%2C%22lastName%22%3A%22Lindi%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Estelle%22%2C%22lastName%22%3A%22Lowry%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mariona%22%2C%22lastName%22%3A%22Bustamante%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Carolina%22%2C%22lastName%22%3A%22Medina-Gomez%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mads%22%2C%22lastName%22%3A%22Melbye%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Kim%20F.%22%2C%22lastName%22%3A%22Michaelsen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Camilla%20S.%22%2C%22lastName%22%3A%22Morgen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Trevor%20A.%22%2C%22lastName%22%3A%22Mori%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tenna%20R.%20H.%22%2C%22lastName%22%3A%22Nielsen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Harri%22%2C%22lastName%22%3A%22Niinikoski%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Albertine%20J.%22%2C%22lastName%22%3A%22Oldehinkel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Katja%22%2C%22lastName%22%3A%22Pahkala%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Kalliope%22%2C%22lastName%22%3A%22Panoutsopoulou%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Oluf%22%2C%22lastName%22%3A%22Pedersen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Craig%20E.%22%2C%22lastName%22%3A%22Pennell%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christine%22%2C%22lastName%22%3A%22Power%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Sijmen%20A.%22%2C%22lastName%22%3A%22Reijneveld%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Fernando%22%2C%22lastName%22%3A%22Rivadeneira%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Angela%22%2C%22lastName%22%3A%22Simpson%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Peter%20D.%22%2C%22lastName%22%3A%22Sly%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jakob%22%2C%22lastName%22%3A%22Stokholm%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Kook%20K.%22%2C%22lastName%22%3A%22Teo%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Elisabeth%22%2C%22lastName%22%3A%22Thiering%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Nicholas%20J.%22%2C%22lastName%22%3A%22Timpson%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andr%5Cu00e9%20G.%22%2C%22lastName%22%3A%22Uitterlinden%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Catharina%20E.%20M.%20van%22%2C%22lastName%22%3A%22Beijsterveldt%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Barbera%20D.%20C.%20van%22%2C%22lastName%22%3A%22Schaik%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Marc%22%2C%22lastName%22%3A%22Vaudel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Elvira%22%2C%22lastName%22%3A%22Verduci%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Rebecca%20K.%22%2C%22lastName%22%3A%22Vinding%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Eleftheria%22%2C%22lastName%22%3A%22Zeggini%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Sylvain%22%2C%22lastName%22%3A%22Sebert%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mads%20V.%22%2C%22lastName%22%3A%22Lind%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christopher%20D.%22%2C%22lastName%22%3A%22Brown%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Loreto%22%2C%22lastName%22%3A%22Santa-Marina%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Eva%22%2C%22lastName%22%3A%22Reischl%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christine%22%2C%22lastName%22%3A%22Frithioff-B%5Cu00f8js%5Cu00f8e%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22David%22%2C%22lastName%22%3A%22Meyre%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Eleanor%22%2C%22lastName%22%3A%22Wheeler%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ken%22%2C%22lastName%22%3A%22Ong%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ellen%20A.%22%2C%22lastName%22%3A%22Nohr%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%20G.%20M.%22%2C%22lastName%22%3A%22Vrijkotte%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Gerard%20H.%22%2C%22lastName%22%3A%22Koppelman%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Robert%22%2C%22lastName%22%3A%22Plomin%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22P%5Cu00e5l%20R.%22%2C%22lastName%22%3A%22Nj%5Cu00f8lstad%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22George%20D.%22%2C%22lastName%22%3A%22Dedoussis%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Philippe%22%2C%22lastName%22%3A%22Froguel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Thorkild%20I.%20A.%22%2C%22lastName%22%3A%22S%5Cu00f8rensen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Bo%22%2C%22lastName%22%3A%22Jacobsson%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Rachel%20M.%22%2C%22lastName%22%3A%22Freathy%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Babette%20S.%22%2C%22lastName%22%3A%22Zemel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Olli%22%2C%22lastName%22%3A%22Raitakari%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Martine%22%2C%22lastName%22%3A%22Vrijheid%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Bjarke%22%2C%22lastName%22%3A%22Feenstra%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Leo-Pekka%22%2C%22lastName%22%3A%22Lyytik%5Cu00e4inen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Harold%22%2C%22lastName%22%3A%22Snieder%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Holger%22%2C%22lastName%22%3A%22Kirsten%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Patrick%20G.%22%2C%22lastName%22%3A%22Holt%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Joachim%22%2C%22lastName%22%3A%22Heinrich%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Elisabeth%22%2C%22lastName%22%3A%22Wid%5Cu00e9n%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jordi%22%2C%22lastName%22%3A%22Sunyer%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Dorret%20I.%22%2C%22lastName%22%3A%22Boomsma%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Marjo-Riitta%22%2C%22lastName%22%3A%22J%5Cu00e4rvelin%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22George%20Davey%22%2C%22lastName%22%3A%22Smith%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jens-Christian%22%2C%22lastName%22%3A%22Holm%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mustafa%22%2C%22lastName%22%3A%22Atalay%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Clare%22%2C%22lastName%22%3A%22Murray%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Hans%22%2C%22lastName%22%3A%22Bisgaard%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mark%20I.%22%2C%22lastName%22%3A%22McCarthy%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Early%20Growth%20Genetics%22%2C%22lastName%22%3A%22Consortium%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Vincent%20W.%20V.%22%2C%22lastName%22%3A%22Jaddoe%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Struan%20F.%20A.%22%2C%22lastName%22%3A%22Grant%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Janine%20F.%22%2C%22lastName%22%3A%22Felix%22%7D%5D%2C%22abstractNote%22%3A%22The%20genetic%20background%20of%20childhood%20body%20mass%20index%20%28BMI%29%2C%20and%20the%20extent%20to%20which%20the%20well-known%20associations%20of%20childhood%20BMI%20with%20adult%20diseases%20are%20explained%20by%20shared%20genetic%20factors%2C%20are%20largely%20unknown.%20We%20performed%20a%20genome-wide%20association%20study%20meta-analysis%20of%20BMI%20in%2061%2C111%20children%20aged%20between%202%20and%2010%20years.%20Twenty-five%20independent%20loci%20reached%20genome-wide%20significance%20in%20the%20combined%20discovery%20and%20replication%20analyses.%20Two%20of%20these%2C%20located%20near%20NEDD4L%20and%20SLC45A3%2C%20have%20not%20previously%20been%20reported%20in%20relation%20to%20either%20childhood%20or%20adult%20BMI.%20Positive%20genetic%20correlations%20of%20childhood%20BMI%20with%20birth%20weight%20and%20adult%20BMI%2C%20waist-to-hip%20ratio%2C%20diastolic%20blood%20pressure%20and%20type%202%20diabetes%20were%20detected%20%28Rg%20ranging%20from%200.11%20to%200.76%2C%20P-values%20%3C0.002%29.%20A%20negative%20genetic%20correlation%20of%20childhood%20BMI%20with%20age%20at%20menarche%20was%20observed.%20Our%20results%20suggest%20that%20the%20biological%20processes%20underlying%20childhood%20BMI%20largely%2C%20but%20not%20completely%2C%20overlap%20with%20those%20underlying%20adult%20BMI.%20The%20well-known%20observational%20associations%20of%20BMI%20in%20childhood%20with%20cardio-metabolic%20diseases%20in%20adulthood%20may%20reflect%20partial%20genetic%20overlap%2C%20but%20in%20light%20of%20previous%20evidence%2C%20it%20is%20also%20likely%20that%20they%20are%20explained%20through%20phenotypic%20continuity%20of%20BMI%20from%20childhood%20into%20adulthood.%22%2C%22date%22%3A%22Oct%2C%202020%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1371%5C%2Fjournal.pgen.1008718%22%2C%22ISSN%22%3A%221553-7404%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fjournals.plos.org%5C%2Fplosgenetics%5C%2Farticle%3Fid%3D10.1371%5C%2Fjournal.pgen.1008718%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-24T13%3A40%3A07Z%22%7D%7D%2C%7B%22key%22%3A%22KISPREAQ%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Poulain%20et%20al.%22%2C%22parsedDate%22%3A%222020-08%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EPoulain%2C%20Tanja%2C%20Carolin%20Sobek%2C%20Juliane%20Ludwig%2C%20Ulrike%20Igel%2C%20Gesine%20Grande%2C%20Verena%20Ott%2C%20Wieland%20Kiess%2C%20Antje%20K%26%23xF6%3Brner%2C%20and%20Mandy%20Vogel.%20%26%23x201C%3BAssociations%20of%20Green%20Spaces%20and%20Streets%20in%20the%20Living%20Environment%20with%20Outdoor%20Activity%2C%20Media%20Use%2C%20Overweight%5C%2FObesity%20and%20Emotional%20Wellbeing%20in%20Children%20and%20Adolescents.%26%23x201D%3B%20%3Ci%3EInternational%20Journal%20of%20Environmental%20Research%20and%20Public%20Health%3C%5C%2Fi%3E%2017%2C%20no.%2017%20%28August%202020%29%3A%206321.%20%3Ca%20class%3D%27zp-ItemURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Fijerph17176321%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Fijerph17176321%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Associations%20of%20Green%20Spaces%20and%20Streets%20in%20the%20Living%20Environment%20with%20Outdoor%20Activity%2C%20Media%20Use%2C%20Overweight%5C%2FObesity%20and%20Emotional%20Wellbeing%20in%20Children%20and%20Adolescents%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Carolin%22%2C%22lastName%22%3A%22Sobek%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Juliane%22%2C%22lastName%22%3A%22Ludwig%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ulrike%22%2C%22lastName%22%3A%22Igel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Gesine%22%2C%22lastName%22%3A%22Grande%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Verena%22%2C%22lastName%22%3A%22Ott%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%5D%2C%22abstractNote%22%3A%22Aspects%20of%20the%20living%20environment%20can%20affect%20health%20and%20wellbeing%20of%20children%20and%20adolescents.%20Whereas%20most%20previous%20studies%20assessed%20the%20more%20distant%20residential%20urban%20environment%2C%20less%20is%20known%20on%20possible%20effects%20of%20the%20close%20environment.%20The%20present%20study%20investigated%20associations%20of%20the%20proportion%20of%20streets%20and%20green%20spaces%20in%20the%20immediate%20urban%20living%20environment%20%2850%2C%20100%20and%20400%20m%20around%20the%20home%29%20with%20media%20use%2C%20outdoor%20activity%2C%20overweight%5C%2Fobesity%20and%20emotional%20problems%20in%20two%20samples%20of%20younger%20%28age%203-10%2C%20n%20%3D%20395%29%20and%20older%20children%20%28age%2010-19%2C%20n%20%3D%20405%29.%20Independently%20of%20socioeconomic%20parameters%2C%20a%20higher%20proportion%20of%20streets%20was%20associated%20with%20overweight%5C%2Fobesity%20%28in%20younger%20and%20older%20children%29%2C%20higher%20media%20use%20%28in%20younger%20children%29%2C%20less%20outdoor%20activity%20and%20more%20emotional%20problems%20%28in%20older%20children%29.%20Older%20children%27s%20outdoor%20activity%20in%20winter%20increased%20with%20increasing%20proportions%20of%20green%20spaces.%20The%20observations%20suggest%20that%20the%20immediate%20urban%20living%20environment%20is%20a%20factor%20that%20can%20affect%20leisure%20behavior%20and%20health%20in%20children.%22%2C%22date%22%3A%22Aug%2C%202020%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.3390%5C%2Fijerph17176321%22%2C%22ISSN%22%3A%221660-4601%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Fijerph17176321%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-24T11%3A01%3A53Z%22%7D%7D%2C%7B%22key%22%3A%22AXENU7F2%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Flemming%20et%20al.%22%2C%22parsedDate%22%3A%222020-07-28%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EFlemming%2C%20Gunter%2C%20Sarah%20Bussler%2C%20Antje%20K%26%23xF6%3Brner%2C%20and%20Wieland%20Kiess.%20%26%23x201C%3BDefinition%20and%20Early%20Diagnosis%20of%20Metabolic%20Syndrome%20in%20Children.%26%23x201D%3B%20%3Ci%3EJournal%20of%20Pediatric%20Endocrinology%20%26amp%3B%20Metabolism%3A%20JPEM%3C%5C%2Fi%3E%2033%2C%20no.%207%20%28July%2028%2C%202020%29%3A%20821%26%23×2013%3B33.%20https%3A%5C%2F%5C%2Fdoi.org%5C%2F%3Ca%20class%3D%27zp-ItemURL%27%20target%3D%27_blank%27%20href%3D%2710.1515%5C%2Fjpem-2019-0552%27%3E10.1515%5C%2Fjpem-2019-0552%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Definition%20and%20Early%20Diagnosis%20of%20Metabolic%20Syndrome%20in%20Children%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Gunter%22%2C%22lastName%22%3A%22Flemming%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Sarah%22%2C%22lastName%22%3A%22Bussler%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%5D%2C%22abstractNote%22%3A%22With%20this%20review%2C%20we%20aim%20to%20focus%20the%20attention%20on%20some%20established%20as%20well%20as%20new%20concepts%20for%20the%20metabolic%20syndrome%20%28MetS%29%20in%20children%20and%20adolescents%20spanning%20from%20definition%20to%20recommendations%20for%20the%20diagnostic%20approach.%20Even%20though%20there%20is%20no%20international%20commonly%20used%20definition%20of%20the%20metabolic%20syndrome%20in%20children%20and%20adolescents%2C%20all%20definitions%20include%20obesity%20as%20precondition%20for%20the%20development%20of%20MetS%20even%20in%20children.%20Obesity%20is%20one%20of%20the%20major%20cardiometabolic%20risk%20factors%20and%20it%20is%20strongly%20linked%20to%20other%20metabolic%20diseases%20like%20hyperlipidemia%2C%20hyperinsulinemia%20as%20well%20as%20hypertension.%20The%20metabolic%20syndrome%20is%20commonly%20known%20as%20a%20constellation%20of%20the%20mentioned%20morbidities.%20Pediatricians%20and%20researchers%20agree%20that%20early%20diagnosis%20and%20early%20interventions%20of%20the%20MetS%20are%20important%20to%20improve%20the%20prevention%20of%20cardiovascular%20disease%20and%20type%202%20diabetes%20in%20adulthood.%20However%2C%20this%20requires%20appropriate%20screening%20tools%20for%20children%20and%20adolescents%20at%20risk%20for%20the%20MetS%20and%20its%20comorbidities.%20Due%20to%20controversies%20regarding%20the%20definition%20of%20MetS%20and%20the%20lack%20of%20consensus%20thresholds%20for%20the%20single%20components%20in%20children%20and%20adolescents%2C%20there%20is%20no%20internationally%20accepted%20diagnostic%20pathway%20for%20MetS%20available.%20However%2C%20several%20consensus%20statements%20and%20national%20guidelines%20for%20the%20assessment%20of%20obesity%20and%20its%20comorbidities%20in%20children%20and%20adolescents%20are%20available.%20Obesity%20seems%20to%20be%20the%20driving%20factor%20for%20the%20development%20of%20the%20other%20risk%20factors%20of%20MetS.%20In%20order%20to%20avoid%20conflicts%20concerning%20the%20definition%20of%20overweight%20and%20obesity%2C%20we%20recommend%20using%20the%20WHO%20definition%20of%20overweight%20%28one%20standard%20deviation%20body%20mass%20index%20for%20age%20and%20sex%20and%20obesity%3B%20two%20standard%20deviations%20body%20mass%20index%20for%20age%20and%20sex%29%20in%20children%20and%20adolescents.%22%2C%22date%22%3A%22Jul%2028%2C%202020%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1515%5C%2Fjpem-2019-0552%22%2C%22ISSN%22%3A%222191-0251%22%2C%22url%22%3A%2210.1515%5C%2Fjpem-2019-0552%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-07T07%3A01%3A48Z%22%7D%7D%2C%7B%22key%22%3A%224VHAYZIQ%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Kiess%20et%20al.%22%2C%22parsedDate%22%3A%222020-05%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EKiess%2C%20Alexandra%2C%20Antje%20K%26%23xF6%3Brner%2C%20Ingo%20D%26%23xE4%3Bhnert%2C%20Mandy%20Vogel%2C%20Franziska%20Markel%2C%20Roman%20A.%20Gebauer%2C%20Wieland%20Kiess%2C%20and%20Christian%20Paech.%20%26%23x201C%3BDoes%20Obesity%20Have%20an%20Effect%20on%20the%20Ecg%20in%20Children%3F%26%23x201D%3B%20%3Ci%3EJournal%20of%20Pediatric%20Endocrinology%20%26amp%3B%20Metabolism%3A%20JPEM%3C%5C%2Fi%3E%2033%2C%20no.%205%20%28May%202020%29%3A%20585%26%23×2013%3B89.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1515%5C%2Fjpem-2019-0539%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1515%5C%2Fjpem-2019-0539%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Does%20Obesity%20Have%20an%20Effect%20on%20the%20Ecg%20in%20Children%3F%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Alexandra%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ingo%22%2C%22lastName%22%3A%22D%5Cu00e4hnert%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Franziska%22%2C%22lastName%22%3A%22Markel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Roman%20A.%22%2C%22lastName%22%3A%22Gebauer%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christian%22%2C%22lastName%22%3A%22Paech%22%7D%5D%2C%22abstractNote%22%3A%22This%20review%20summarizes%20current%20data%20on%20influences%20of%20childhood%20obesity%20on%20the%2012-lead%20electrocardiogram%20%28ECG%29.%20Studies%20on%20obese%20adults%20showed%20a%20higher%20risk%20of%20cardiovascular%20complications%20and%20also%2C%20partly%20pathological%2C%20ECG%20alterations.%20Data%20on%20ECG%20alterations%20in%20obese%20children%20is%20rare.%20In%20current%20studies%2C%20no%20pathological%20findings%20were%20found.%20All%20alterations%2C%20which%20mimic%20the%20later%20pathological%20phenomena%20in%20obese%20adults%2C%20were%20within%20normal%20ranges.%20Studies%20reported%20significantly%20longer%20P-wave%20time%20and%20P-wave%20dispersion%20%28Pd%29%20in%20obese%20children%20%5B%5Cu00dcner%20A%2C%20Do%5Cu011fan%20M%2C%20Epcacan%20Z%2C%20Ep%5Cu00e7a%5Cu00e7an%20S.%20The%20effect%20of%20childhood%20obesity%20on%20cardiac%20functions.%20J%20Pediatr%20Endocr%20Met%202014%3B27%3A261-71.%5D%2C%20no%20correlation%20of%20heart%20rate%2C%20P-wave%2C%20or%20QT%20dispersions%20%28QTd%29%20%5BAky%5Cu00fcz%20A%2C%20Alpsoy%20S%2C%20Akkoyun%20DC%2C%20Nalbanto%5Cu01e7lu%20B%2C%20T%5Cu00fcl%5Cu00fcba%5Cu0219%20F%2C%20et%20al.%20Effect%20of%20overweight%20on%20P-wave%20and%20QT%20dispersions%20in%20childhood.%20Turk%20Kardiyol%20Dern%20Ars%202013%3B41%3A515-21.%5D%2C%20significantly%20higher%20QTd%20in%20obese%20children%20%5BYildirim%20S%2C%20Binnetoglu%20FK%2C%20Battal%20F%2C%20Aylanc%20H%2C%20Nazan%20Kaymaz%20N%2C%20et%20al.%20Relation%20between%20QT%20variables%20and%20left%20ventricular%20geometry%20in%20athletes%20and%20obese%20children.%20Acta%20Med%20Port%202016%3B29%3A95-100.%5D%2C%20no%20significant%20association%20between%20obesity%20and%20QTc%20interval%20%28QTc%29%2C%20but%20longer%20PR%20intervals%2C%20wider%20QRS%20duration%20and%20left%20axis%20shifting%20of%20frontal%20P-wave%2C%20QRS%20and%20T-wave%20axes%20%5BSun%20G%2C%20Li%20Y%2C%20Zho%20X%2C%20Guuo%20X%2C%20Zhang%20X%2C%20et%20al.%20Association%20between%20obesity%20and%20ECG%20variables%20in%20children%20and%20adolescents%3A%20a%20cross-sectional%20study.%20Exp%20Ther%20Med%202013%3B6%3A1455-62.%5D%2C%20significant%20prolongation%20of%20QTc%2C%20T%20peak-to-end%2C%20and%20QTd%20in%20the%20obese%20children%20%5BPaech%20C%2C%20Liebold%20A%2C%20Gebauer%20RA%2C%20Wagner%20F%2C%20Vogel%20M%2C%20et%20al.%20Relative%20QT%20interval%20prolongation%20and%20electrical%20inhomogeneity%20of%20cardiac%20repolarization%20in%20childhood%20obesity.%20Prog%20Pediatr%20Cardiol%202017%3B47%3A64-7.%5D%2C%20slight%20shift%20to%20the%20left%20in%20the%20QRS%20axis%20%28with%20no%20changes%20in%20the%20P%20axis%29%2C%20increased%20amplitudes%20of%20the%20left-sided%20leads%20in%20obese%20children%2C%20and%20no%20correlation%20of%20the%20heart%20rate%20with%20the%20weight%20%5BPaech%20C%2C%20Anhalt%20M%2C%20Gebauer%20RA%2C%20Wagner%20F%2C%20Vogel%20M%2C%20et%20al.%20New%20normal%20limits%20for%20pediatric%20ECG%20in%20childhood%20obesity%3F%20Influence%20of%20childhood%20obesity%20on%20the%20ECG.%20Prog%20Pediatr%20Cardiol%202018%3B48%3A119-23.%5D.%20Altogether%2C%20the%20study%20results%20are%20inconsistent.%20Clearly%2C%20pathological%20phenomena%20in%20the%20ECG%20of%20obese%20children%20were%20not%20reported%3A%20only%20preliminary%20stages%20like%20QTc%20prolongation%20within%20the%20norm%20were%20found.%20The%20pathological%20alterations%20seen%20in%20adult%20obese%20patients%20are%20not%20%28yet%29%20seen%20in%20childhood.%20The%20slight%20changes%20reported%20in%20childhood%20obesity%20are%20likely%20to%20manifest%20later%20and%20to%20develop%20into%20pathological%20phenomena%20in%20obese%20adults%20and%2C%20therefore%2C%20might%20increase%20the%20risk%20of%20cardiovascular%20events%20like%20arrhythmia%20and%20sudden%20cardiac%20death%20in%20adulthood.%22%2C%22date%22%3A%22May%2C%202020%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1515%5C%2Fjpem-2019-0539%22%2C%22ISSN%22%3A%222191-0251%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Forgid.org%5C%2F10.1515%5C%2Fjpem-2019-0539%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-07T07%3A01%3A42Z%22%7D%7D%2C%7B%22key%22%3A%22TEN9EGD3%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Geserick%20et%20al.%22%2C%22parsedDate%22%3A%222020%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EGeserick%2C%20M.%2C%20M.%20Vogel%2C%20F.%20Eckelt%2C%20M.%20Schlingmann%2C%20A.%20Hiemisch%2C%20R.%20Baber%2C%20J.%20Thiery%2C%20A.%20K%26%23xF6%3Brner%2C%20W.%20Kiess%2C%20and%20J.%20Kratzsch.%20%26%23x201C%3BChildren%20and%20Adolescents%20with%20Obesity%20Have%20Reduced%20Serum%20Bone%20Turnover%20Markers%20and%2025-Hydroxyvitamin%20D%20but%20Increased%20Parathyroid%20Hormone%20Concentrations%20%26%23×2013%3B%20Results%20Derived%20from%20New%20Pediatric%20Reference%20Ranges.%26%23x201D%3B%20%3Ci%3EBone%3C%5C%2Fi%3E%20132%20%282020%29%3A%20115124.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.bone.2019.115124%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.bone.2019.115124%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Children%20and%20Adolescents%20with%20Obesity%20Have%20Reduced%20Serum%20Bone%20Turnover%20Markers%20and%2025-Hydroxyvitamin%20D%20but%20Increased%20Parathyroid%20Hormone%20Concentrations%20%5Cu2013%20Results%20Derived%20from%20New%20Pediatric%20Reference%20Ranges%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22M.%22%2C%22lastName%22%3A%22Geserick%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22M.%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22F.%22%2C%22lastName%22%3A%22Eckelt%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22M.%22%2C%22lastName%22%3A%22Schlingmann%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22A.%22%2C%22lastName%22%3A%22Hiemisch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22R.%22%2C%22lastName%22%3A%22Baber%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J.%22%2C%22lastName%22%3A%22Thiery%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22A.%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22W.%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J.%22%2C%22lastName%22%3A%22Kratzsch%22%7D%5D%2C%22abstractNote%22%3A%22Background%3A%20We%20aimed%20to%20establish%20age-%20and%20gender-specific%20reference%20ranges%20for%20concentrations%20of%20the%20bone%20markers%20osteocalcin%20%28OC%29%2C%20procollagen%20type%201%20N-propeptides%20%28PINP%29%20and%20carboxy-terminal%20cross-linking%20telopeptide%20of%20type%201%20collagen%20%28CTX-I%29%20as%20well%20as%20for%20the%20calciotropic%20hormones%2025-hydroxyvitamin%20D%20%5B25%28OH%29D%5D%20and%20parathyroid%20hormone%20%28PTH%29%20in%20healthy%20infants%2C%20children%20and%20adolescents.%20In%20addition%2C%20the%20effect%20of%20age%2C%20gender%2C%20puberty%20and%20body%20mass%20index%20%28BMI%29%20on%20bone%20markers%20was%20investigated.%5CnMethods%3A%202416%20healthy%20subjects%20%285714%20blood%20withdrawals%29%2C%20aged%203%20months%20to%2017%20years%2C%20were%20included%20to%20estimate%20the%20age-%20and%20gender-dependence%20of%20reference%20ranges.%20Subsequently%2C%20measured%20values%20of%20the%20biomarkers%20were%20transformed%20to%20standard%20deviation%20scores%20%28SDS%29%20and%20their%20associations%20with%20age%2C%20gender%20and%20puberty%20were%20analyzed.%20Bone%20marker-SDS%20values%20of%20the%20reference%20cohort%20were%20compared%20with%20an%20obese%20cohort%20%28n%20%3D%20317%20and%20489%20blood%20withdrawals%29%20to%20analyze%20the%20effect%20of%20BMI.%5CnResults%3A%20OC%2C%20PINP%20and%20CTX-I%20showed%20a%20distinct%20age-%20and%20gender-dependence%20with%20peak%20levels%20at%2010%20to%2011%20years%20%28girls%2C%20Tanner%203%29%20and%2013%20years%20%28boys%2C%20Tanner%203%5Cu20134%29.%20Children%20with%20obesity%20had%20significantly%20lower%20SDS%20levels%20for%20OC%20%28%5Cu22120.44%29%2C%20PINP%20%28%5Cu22120.27%29%2C%20CTX-I%20%28%5Cu22120.33%29%2C%2025%28OH%29D%20%28%5Cu22120.43%29%20and%20higher%20SDS%20levels%20for%20PTH%20%28%2B0.44%29%20than%20the%20reference%20cohort.%5CnConclusions%3A%20OC%2C%20PINP%20and%20CTX-I%20vary%20with%20age%2C%20gender%20and%20pubertal%20stage.%20The%20body%20weight%20status%20has%20to%20be%20considered%20in%20the%20interpretation%20of%20pediatric%20OC%2C%20PINP%2C%20CTX-I%2C%2025%28OH%29D%20and%20PTH%20levels.%20Consequences%20of%20childhood%20obesity%20on%20bone%20health%20should%20be%20carefully%20investigated%20in%20long-term%20studies.%22%2C%22date%22%3A%2203%5C%2F2020%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1016%5C%2Fj.bone.2019.115124%22%2C%22ISSN%22%3A%2287563282%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Flinkinghub.elsevier.com%5C%2Fretrieve%5C%2Fpii%5C%2FS8756328219304181%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222024-01-02T15%3A33%3A44Z%22%7D%7D%2C%7B%22key%22%3A%22YQVV88KP%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Schmidt%20et%20al.%22%2C%22parsedDate%22%3A%222019-10%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3ESchmidt%2C%20Ricarda%2C%20Andreas%20Hiemisch%2C%20Wieland%20Kiess%2C%20and%20Anja%20Hilbert.%20%26%23x201C%3BInteraction%20Effects%20of%20Child%20Weight%20Status%20and%20Parental%20Feeding%20Practices%20on%20Children%26%23×2019%3Bs%20Eating%20Disorder%20Symptomatology.%26%23x201D%3B%20%3Ci%3ENutrients%3C%5C%2Fi%3E%2011%2C%20no.%2010%20%28October%202019%29%3A%202433.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Fnu11102433%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Fnu11102433%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Interaction%20Effects%20of%20Child%20Weight%20Status%20and%20Parental%20Feeding%20Practices%20on%20Children%27s%20Eating%20Disorder%20Symptomatology%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ricarda%22%2C%22lastName%22%3A%22Schmidt%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andreas%22%2C%22lastName%22%3A%22Hiemisch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anja%22%2C%22lastName%22%3A%22Hilbert%22%7D%5D%2C%22abstractNote%22%3A%22%281%29%20Background%3A%20Research%20on%20parental%20feeding%20practices%20and%20non-normative%20eating%20behavior%20including%20loss%20of%20control%20%28LOC%29%20eating%20and%20eating%20disorder%20psychopathology%20indicated%20separate%20associations%20of%20these%20variables%20with%20child%20weight%20status%2C%20especially%20in%20early%20childhood.%20This%20study%20cross-sectionally%20examined%20interaction%20effects%20of%20restriction%2C%20monitoring%2C%20pressure%20to%20eat%2C%20and%20children%27s%20weight%20status%20on%20disordered%20eating%20in%20children%20aged%208-13%20years.%20%282%29%20Methods%3A%20A%20population-based%20sample%20of%20N%20%3D%20904%20children%20and%20their%20mothers%20completed%20the%20Eating%20Disorder%20Examination%20Questionnaire%20for%20Children%20and%20the%20Child%20Feeding%20Questionnaire.%20Child%20anthropometrics%20were%20objectively%20measured.%20Hierarchical%20linear%20and%20logistic%20regression%20analyses%20were%20conducted%20for%20cross-sectionally%20predicting%20global%20eating%20disorder%20psychopathology%20and%20recurrent%20LOC%20eating%20by%20feeding%20practices%20and%20child%20weight%20status%20for%20younger%20%288-10%20years%29%20and%20older%20%2811-13%20years%29%20ages.%20%283%29%20Results%3A%20Restriction%20x%20Child%20weight%20status%20significantly%20predicted%20global%20eating%20disorder%20psychopathology%20in%20younger%20children%20and%20recurrent%20LOC%20eating%20in%20older%20children.%20Monitoring%20x%20Child%20weight%20status%20significantly%20predicted%20eating%20disorder%20psychopathology%20in%20older%20children.%20A%20higher%20versus%20lower%20child%20weight%20status%20was%20associated%20with%20adverse%20eating%20behaviors%2C%20particularly%20in%20children%20with%20mothers%20reporting%20high%20restriction%20and%20monitoring.%20%284%29%20Conclusions%3A%20Detrimental%20associations%20between%20higher%20child%20weight%20status%20and%20child%20eating%20disorder%20symptomatology%20held%20especially%20true%20for%20children%20whose%20mothers%20strongly%20control%20child%20food%20intake.%22%2C%22date%22%3A%22Oct%2C%202019%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.3390%5C%2Fnu11102433%22%2C%22ISSN%22%3A%222072-6643%22%2C%22url%22%3A%22http%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Fnu11102433%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-24T11%3A23%3A27Z%22%7D%7D%2C%7B%22key%22%3A%22S6T8FXVC%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Gramss%20et%20al.%22%2C%22parsedDate%22%3A%222019-08%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EGramss%2C%20Manuela%2C%20Tobias%20Lipek%2C%20Mandy%20Vogel%2C%20Johannes%20Remmler%2C%20Andreas%20Hiemisch%2C%20Anne%20Jurkutat%2C%20Jon%20Genuneit%2C%20Antje%20K%26%23xF6%3Brner%2C%20and%20Wieland%20Kiess.%20%26%23x201C%3BOverweight%20Proxies%20Are%20Associated%20with%20Atopic%20Asthma%3A%20A%20Matched%20Case-Control%20Study.%26%23x201D%3B%20%3Ci%3EHormone%20Research%20in%20Paediatrics%3C%5C%2Fi%3E%2091%2C%20no.%206%20%28August%202019%29%3A%20380%26%23×2013%3B90.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1159%5C%2F000501685%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1159%5C%2F000501685%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Overweight%20Proxies%20Are%20Associated%20with%20Atopic%20Asthma%3A%20A%20Matched%20Case-Control%20Study%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Manuela%22%2C%22lastName%22%3A%22Gramss%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tobias%22%2C%22lastName%22%3A%22Lipek%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Johannes%22%2C%22lastName%22%3A%22Remmler%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andreas%22%2C%22lastName%22%3A%22Hiemisch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anne%22%2C%22lastName%22%3A%22Jurkutat%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jon%22%2C%22lastName%22%3A%22Genuneit%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%5D%2C%22abstractNote%22%3A%22BACKGROUND%3A%20Many%20studies%20have%20documented%20a%20link%20between%20overweight%20and%20asthma%20in%20children%20with%20contradictory%20results%20regarding%20the%20best%20way%20to%20measure%20overweight.%20Moreover%2C%20often%2C%20the%20dynamic%20development%20of%20atopy%2C%20overweight%2C%20and%20asthma%20is%20controlled%20for%20age%20dependency%20insufficiently.%5CnOBJECTIVE%3A%20This%20study%20assesses%20and%20compares%20the%20associations%20of%20overweight%20measured%20as%20waist%20circumference%2C%20waist%20to%20height%20ratio%20%28WHtR%29%2C%20neck%20circumference%2C%20and%20body%20mass%20index%20with%20the%20occurrence%20of%20asthma%20-%20best%20possibly%20controlling%20for%20age-dependencies%20of%20these%20parameters.%5CnMETHODS%3A%20From%20a%20sample%20of%202%2C511%20children%20aged%206-17%20years%2C%20we%20matched%20157%20children%20with%20asthma%20with%202%20controls%20%28n%20%3D%20471%29%20according%20to%20age%20and%20atopy%20status%20and%20performed%20conditional%20logistic%20regression%20analyses.%20We%20further%20investigated%20the%20role%20of%20known%20influencing%20factors%20of%20asthma%20occurrence.%5CnRESULTS%3A%20In%20children%20with%20atopy%2C%20all%20overweight%20proxies%20were%20consistently%20positively%20associated%20with%20asthma.%20Statistical%20significance%20was%20reached%20for%20WHtR-SD%20score%20%28OR%201.26%2C%2095%25%20CI%201.03-1.54%2C%20p%20%3D%200.025%29%20and%20persisted%20when%20further%20covariates%2C%20such%20as%20birth%20weight%20or%20social%20status%2C%20were%20added%20to%20the%20model.%20Groups%20of%20atopic%20versus%20nonatopic%20participants%20do%20not%20differ%20in%20levels%20of%20interleukin-6%20or%20high-sensitivity%20C-reactive%20protein.%5CnCONCLUSION%3A%20In%20our%20cohort%2C%20overweight%20seems%20to%20carry%20a%20risk%20for%20asthma%20only%20if%20accompanied%20with%20atopy.%20We%20call%20for%20more%20strict%20age%20matching%20in%20pediatric%20cohort%20studies%20and%20longitudinal%20studies%20for%20a%20better%20understanding%20for%20causal%20links%20of%20overweight%2C%20atopy%2C%20and%20asthma.%22%2C%22date%22%3A%222019-08%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1159%5C%2F000501685%22%2C%22ISSN%22%3A%221663-2826%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222024-07-12T06%3A38%3A08Z%22%7D%7D%2C%7B%22key%22%3A%22F4Z2WE55%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Buzek%20et%20al.%22%2C%22parsedDate%22%3A%222019-04-01%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EBuzek%2C%20Theresa%2C%20Tanja%20Poulain%2C%20Mandy%20Vogel%2C%20Christoph%20Engel%2C%20Sarah%20Bussler%2C%20Antje%20K%26%23xF6%3Brner%2C%20Andreas%20Hiemisch%2C%20and%20Wieland%20Kiess.%20%26%23x201C%3BRelations%20Between%20Sleep%20Duration%20with%20Overweight%20and%20Academic%20Stress%26%23×2014%3BJust%20a%20Matter%20of%20the%20Socioeconomic%20Status%3F%26%23x201D%3B%20%3Ci%3ESleep%20Health%3C%5C%2Fi%3E%205%2C%20no.%202%20%28April%201%2C%202019%29%3A%20208%26%23×2013%3B15.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.sleh.2018.12.004%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.sleh.2018.12.004%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Relations%20Between%20Sleep%20Duration%20with%20Overweight%20and%20Academic%20Stress%5Cu2014Just%20a%20Matter%20of%20the%20Socioeconomic%20Status%3F%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Theresa%22%2C%22lastName%22%3A%22Buzek%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christoph%22%2C%22lastName%22%3A%22Engel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Sarah%22%2C%22lastName%22%3A%22Bussler%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andreas%22%2C%22lastName%22%3A%22Hiemisch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%5D%2C%22abstractNote%22%3A%22Objectives%5CnShorter%20sleep%20duration%20in%20childhood%20has%20already%20been%20associated%20with%20health-related%20and%20psychological%20factors%2C%20such%20as%20overweight%5C%2Fobesity%20or%20stress.%20This%20study%20investigates%20associations%20of%20sleep%20duration%20with%20overweight%5C%2Fobesity%20and%20stress%20related%20to%20academic%20success%20in%20school%20%28%5Cu201cacademic%20stress%5Cu201d%29%20in%20dependence%20on%20children%5Cu2019s%20socioeconomic%20status.%5CnDesign%5CnCross-sectional.%5CnSetting%5CnLIFE%20Child%20Study%2C%20a%20study%20investigating%20child%20development%20from%20pregnancy%20to%20adulthood.%5CnParticipants%5CnA%20total%20of%201537%20%282325%20observations%29%201-%20to%2014-year-old%20children%20were%20considered.%20Analyses%20on%20academic%20stress%20were%20performed%20in%20a%20subgroup%20of%20450%20school-aged%20children%20%28631%20observations%29.%5CnMeasurements%5CnAssociations%20between%20sleep%20duration%20and%20overweight%5C%2Fobesity%20as%20well%20as%20academic%20stress%20were%20analyzed%20using%20linear%20mixed-effect%20regression%20models%20controlling%20for%20multiple%20visits.%20Importantly%2C%20all%20associations%20were%20checked%20for%20interactions%20with%20families%5Cu2019%20socioeconomic%20status.%5CnResults%5CnThe%20analyses%20revealed%20negative%20associations%20between%20sleep%20duration%20and%20overweight%5C%2Fobesity%20as%20well%20as%20academic%20stress%2C%20which%2C%20however%2C%20were%20only%20observable%20in%20children%20from%20families%20with%20a%20low%20socioeconomic%20status.%20The%20associations%20were%20consistent%20across%20all%20ages.%5CnConclusions%5CnThe%20findings%20suggest%20that%20children%20from%20families%20with%20a%20low%20socioeconomic%20status%20have%20a%20higher%20susceptibility%20for%20risk%20factors%20promoting%20sleep%20deficiency%2C%20overweight%2C%20or%20academic%20stress%2C%20for%20example%2C%20unhealthy%20food%20intake%2C%20high%20media%20consumption%2C%20or%20the%20loss%20of%20coping%20strategies%20for%20academic%20stress%20at%20school.%22%2C%22date%22%3A%22April%201%2C%202019%22%2C%22language%22%3A%22%22%2C%22DOI%22%3A%2210.1016%5C%2Fj.sleh.2018.12.004%22%2C%22ISSN%22%3A%222352-7218%22%2C%22url%22%3A%22http%3A%5C%2F%5C%2Fwww.sciencedirect.com%5C%2Fscience%5C%2Farticle%5C%2Fpii%5C%2FS235272181830247X%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-23T10%3A56%3A31Z%22%7D%7D%2C%7B%22key%22%3A%22YZSQCZ8M%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Schmidt%20et%20al.%22%2C%22parsedDate%22%3A%222019-04%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3ESchmidt%2C%20Jana%2C%20Pia%20Strecker%2C%20Markus%20Kreuz%2C%20Markus%20L%26%23xF6%3Bffler%2C%20Wieland%20Kiess%2C%20Christian%20Hirsch%2C%20Joachim%20Thiery%2C%20et%20al.%20%26%23x201C%3BStress-Related%20Hormones%20in%20Association%20with%20Periodontal%20Condition%20in%20Adolescents-Results%20of%20the%20Epidemiologic%20Life%20Child%20Study.%26%23x201D%3B%20%3Ci%3EClinical%20Oral%20Investigations%3C%5C%2Fi%3E%2023%2C%20no.%204%20%28April%202019%29%3A%201793%26%23×2013%3B1802.%20https%3A%5C%2F%5C%2Fdoi.org%5C%2F%3Ca%20class%3D%27zp-ItemURL%27%20target%3D%27_blank%27%20href%3D%2710.1007%5C%2Fs00784-018-2599-3%27%3E10.1007%5C%2Fs00784-018-2599-3%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Stress-Related%20Hormones%20in%20Association%20with%20Periodontal%20Condition%20in%20Adolescents-Results%20of%20the%20Epidemiologic%20Life%20Child%20Study%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jana%22%2C%22lastName%22%3A%22Schmidt%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Pia%22%2C%22lastName%22%3A%22Strecker%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Markus%22%2C%22lastName%22%3A%22Kreuz%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Markus%22%2C%22lastName%22%3A%22L%5Cu00f6ffler%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christian%22%2C%22lastName%22%3A%22Hirsch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Joachim%22%2C%22lastName%22%3A%22Thiery%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ronny%22%2C%22lastName%22%3A%22Baber%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Yoon%20Ju%22%2C%22lastName%22%3A%22Bae%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J%5Cu00fcrgen%22%2C%22lastName%22%3A%22Kratzsch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Rainer%22%2C%22lastName%22%3A%22Haak%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Dirk%22%2C%22lastName%22%3A%22Ziebolz%22%7D%5D%2C%22abstractNote%22%3A%22OBJECTIVES%3A%20The%20aim%20of%20this%20study%20was%20to%20investigate%20the%20associations%20between%20blood%20levels%20of%20stress-related%20hormones%20and%20early%20signs%20of%20periodontal%20disease%20in%20children%20and%20adolescents.%5CnMATERIALS%20AND%20METHODS%3A%20Within%20the%20LIFE%20%28Leipzig%20research%20center%20for%20civilization%20diseases%29%20Child%20study%2C%20498%20adolescents%20%2810%20to%2018%5Cu00a0years%29%20were%20included.%20Early%20signs%20of%20periodontal%20inflammation%20were%20measured%20by%20probing%20depth%20%28PD%29%20at%20six%20index%20teeth%20%2816%2C%2011%2C%2026%2C%2036%2C%2031%2C%2046%29.%20Blood%20levels%20of%20stress-related%20hormones%20%28cortisol%2C%20dehydroepiandosterone-sulfate%20%5BDHEA-S%5D%29%20and%2C%20additionally%20interleukine-6%20%28IL-6%29%20were%20measured.%20Socioeconomic%20status%2C%20oral%20hygiene%2C%20orthodontic%20appliances%2C%20and%20nutritional%20status%2C%20recorded%20by%20body-mass-index-standard-deviation-score%20%28BMI-SDS%29%2C%20were%20considered%20as%20confounding%20factors.%20Additionally%2C%20in%2098%20participants%2C%20an%20oral%20chairside%20active%20matrix%20metalloproteinase-8%20%28aMMP-8%29%20test%20was%20performed.%20Statistical%20tests%20are%20the%20Mann-Whitney%20U%20tests%2C%20chi-squared%20tests%20and%20multivariate%20logistic%20regression%20model.%5CnRESULTS%3A%20IL-6%2C%20BMI-SDS%20as%20well%20as%20positive%20aMMP-8%20test%20result%20were%20significantly%20associated%20with%20maximum%20PD%5Cu2009%3E%5Cu20093%5Cu00a0mm%20%28p%5Cu00a0%3C%5Cu20090.05%29.%20However%2C%20no%20statistically%20significant%20associations%20between%20stress-related%20hormones%20%28cortisol%20and%20DHEA-S%29%20and%20presence%20of%20maximum%20PD%20%3E%5Cu20093%5Cu00a0mm%20were%20found%20%28p%5Cu00a0%3E%5Cu20090.05%29.%20Higher%20DHEA-S%20and%20BMI%20were%20associated%20with%20positive%20aMMP-8%20result%2C%20even%20after%20adjusting%20for%20age%20and%20gender%20%28p%5Cu00a0%3D%5Cu20090.027%2C%20padj%5Cu00a0%3D%5Cu20090.026%29.%5CnCONCLUSION%3A%20The%20results%20reveal%20no%20associations%20between%20PD%20and%20stress-related%20hormones%20cortisol%20and%20DHEA-S.%20aMMP-8%20test%20result%20might%20be%20associated%20with%20DHEA-S%20level.%20Nutritional%20status%20seems%20to%20influence%20periodontal%20disease%20in%20adolescents.%5CnCLINICAL%20RELEVANCE%3A%20DHEA-S%20and%20BMI-SDS%20show%20associations%20with%20early%20signs%20of%20periodontal%20disease%20in%20adolescents%20aged%2010%20to%2018%5Cu00a0years.%20This%20association%20should%20be%20confirmed%20by%20the%20investigation%20of%20high-risk%20groups.%22%2C%22date%22%3A%22Apr%202019%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1007%5C%2Fs00784-018-2599-3%22%2C%22ISSN%22%3A%221436-3771%22%2C%22url%22%3A%2210.1007%5C%2Fs00784-018-2599-3%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-24T11%3A21%3A35Z%22%7D%7D%2C%7B%22key%22%3A%22FEX36HUJ%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22K%5Cu00f6rner%20et%20al.%22%2C%22parsedDate%22%3A%222019-01%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EK%26%23xF6%3Brner%2C%20Antje%2C%20Wieland%20Kiess%2C%20and%20Mandy%20Vogel.%20%26%23x201C%3BPersistence%20of%20Obesity%20from%20Early%20Childhood%20Onward.%26%23x201D%3B%20%3Ci%3EThe%20New%20England%20Journal%20of%20Medicine%3C%5C%2Fi%3E%20380%2C%20no.%202%20%28January%202019%29%3A%20194%26%23×2013%3B95.%20%3Ca%20class%3D%27zp-ItemURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1056%5C%2FNEJMc1814961%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1056%5C%2FNEJMc1814961%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Persistence%20of%20Obesity%20from%20Early%20Childhood%20Onward%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%5D%2C%22abstractNote%22%3A%22%22%2C%22date%22%3A%22Jan%2C%202019%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1056%5C%2FNEJMc1814961%22%2C%22ISSN%22%3A%221533-4406%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1056%5C%2FNEJMc1814961%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-07T07%3A01%3A41Z%22%7D%7D%2C%7B%22key%22%3A%2226LSSNM7%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Geserick%20et%20al.%22%2C%22parsedDate%22%3A%222018-10%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EGeserick%2C%20Mandy%2C%20Mandy%20Vogel%2C%20Ruth%20Gausche%2C%20Tobias%20Lipek%2C%20Ulrike%20Spielau%2C%20Eberhard%20Keller%2C%20Roland%20Pf%26%23xE4%3Bffle%2C%20Wieland%20Kiess%2C%20and%20Antje%20K%26%23xF6%3Brner.%20%26%23x201C%3BAcceleration%20of%20BMI%20in%20Early%20Childhood%20and%20Risk%20of%20Sustained%20Obesity.%26%23x201D%3B%20%3Ci%3EThe%20New%20England%20Journal%20of%20Medicine%3C%5C%2Fi%3E%20379%2C%20no.%2014%20%28October%202018%29%3A%201303%26%23×2013%3B12.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1056%5C%2FNEJMoa1803527%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1056%5C%2FNEJMoa1803527%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Acceleration%20of%20BMI%20in%20Early%20Childhood%20and%20Risk%20of%20Sustained%20Obesity%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Geserick%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ruth%22%2C%22lastName%22%3A%22Gausche%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tobias%22%2C%22lastName%22%3A%22Lipek%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ulrike%22%2C%22lastName%22%3A%22Spielau%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Eberhard%22%2C%22lastName%22%3A%22Keller%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Roland%22%2C%22lastName%22%3A%22Pf%5Cu00e4ffle%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%5D%2C%22abstractNote%22%3A%22BACKGROUND%3A%20The%20dynamics%20of%20body-mass%20index%20%28BMI%29%20in%20children%20from%20birth%20to%20adolescence%20are%20unclear%2C%20and%20whether%20susceptibility%20for%20the%20development%20of%20sustained%20obesity%20occurs%20at%20a%20specific%20age%20in%20children%20is%20important%20to%20determine.%5CnMETHODS%3A%20To%20assess%20the%20age%20at%20onset%20of%20obesity%2C%20we%20performed%20prospective%20and%20retrospective%20analyses%20of%20the%20course%20of%20BMI%20over%20time%20in%20a%20population-based%20sample%20of%2051%2C505%20children%20for%20whom%20sequential%20anthropometric%20data%20were%20available%20during%20childhood%20%280%20to%2014%20years%20of%20age%29%20and%20adolescence%20%2815%20to%2018%20years%20of%20age%29.%20In%20addition%2C%20we%20assessed%20the%20dynamics%20of%20annual%20BMI%20increments%2C%20defined%20as%20the%20change%20in%20BMI%20standard-deviation%20score%20per%20year%2C%20during%20childhood%20in%2034%2C196%20children.%5CnRESULTS%3A%20In%20retrospective%20analyses%2C%20we%20found%20that%20most%20of%20the%20adolescents%20with%20normal%20weight%20had%20always%20had%20a%20normal%20weight%20throughout%20childhood.%20Approximately%20half%20%2853%25%29%20of%20the%20obese%20adolescents%20had%20been%20overweight%20or%20obese%20from%205%20years%20of%20age%20onward%2C%20and%20the%20BMI%20standard-deviation%20score%20further%20increased%20with%20age.%20In%20prospective%20analyses%2C%20we%20found%20that%20almost%2090%25%20of%20the%20children%20who%20were%20obese%20at%203%20years%20of%20age%20were%20overweight%20or%20obese%20in%20adolescence.%20Among%20the%20adolescents%20who%20were%20obese%2C%20the%20greatest%20acceleration%20in%20annual%20BMI%20increments%20had%20occurred%20between%202%20and%206%20years%20of%20age%2C%20with%20a%20further%20rise%20in%20BMI%20percentile%20thereafter.%20High%20acceleration%20in%20annual%20BMI%20increments%20during%20the%20preschool%20years%20%28but%20not%20during%20the%20school%20years%29%20was%20associated%20with%20a%20risk%20of%20overweight%20or%20obesity%20in%20adolescence%20that%20was%201.4%20times%20as%20high%20as%20the%20risk%20among%20children%20who%20had%20had%20stable%20BMI.%20The%20rate%20of%20overweight%20or%20obesity%20in%20adolescence%20was%20higher%20among%20children%20who%20had%20been%20large%20for%20gestational%20age%20at%20birth%20%2843.7%25%29%20than%20among%20those%20who%20had%20been%20at%20an%20appropriate%20weight%20for%20gestational%20age%20%2828.4%25%29%20or%20small%20for%20gestational%20age%20%2827.2%25%29%2C%20which%20corresponded%20to%20a%20risk%20of%20adolescent%20obesity%20that%20was%201.55%20times%20as%20high%20among%20those%20who%20had%20been%20large%20for%20gestational%20age%20as%20among%20the%20other%20groups.%5CnCONCLUSIONS%3A%20Among%20obese%20adolescents%2C%20the%20most%20rapid%20weight%20gain%20had%20occurred%20between%202%20and%206%20years%20of%20age%3B%20most%20children%20who%20were%20obese%20at%20that%20age%20were%20obese%20in%20adolescence.%20%28Funded%20by%20the%20German%20Research%20Council%20for%20the%20Clinical%20Research%20Center%20%5C%22Obesity%20Mechanisms%5C%22%20and%20others%3B%20ClinicalTrials.gov%20number%2C%20NCT03072537%20.%29.%22%2C%22date%22%3A%22Oct%2C%202018%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1056%5C%2FNEJMoa1803527%22%2C%22ISSN%22%3A%221533-4406%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-07T07%3A01%3A47Z%22%7D%7D%2C%7B%22key%22%3A%22SFPARI6Q%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Loeffler-Wirth%20et%20al.%22%2C%22parsedDate%22%3A%222018-09%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3ELoeffler-Wirth%2C%20Henry%2C%20Mandy%20Vogel%2C%20Toralf%20Kirsten%2C%20Fabian%20Glock%2C%20Tanja%20Poulain%2C%20Antje%20K%26%23xF6%3Brner%2C%20Markus%20Loeffler%2C%20Wieland%20Kiess%2C%20and%20Hans%20Binder.%20%26%23x201C%3BLongitudinal%20Anthropometry%20of%20Children%20and%20Adolescents%20Using%203d-Body%20Scanning.%26%23x201D%3B%20%3Ci%3EPloS%20One%3C%5C%2Fi%3E%2013%2C%20no.%209%20%28September%202018%29%3A%20e0203628.%20https%3A%5C%2F%5C%2Fdoi.org%5C%2F%3Ca%20class%3D%27zp-ItemURL%27%20target%3D%27_blank%27%20href%3D%2710.1371%5C%2Fjournal.pone.0203628%27%3E10.1371%5C%2Fjournal.pone.0203628%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Longitudinal%20Anthropometry%20of%20Children%20and%20Adolescents%20Using%203d-Body%20Scanning%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Henry%22%2C%22lastName%22%3A%22Loeffler-Wirth%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Toralf%22%2C%22lastName%22%3A%22Kirsten%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Fabian%22%2C%22lastName%22%3A%22Glock%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Markus%22%2C%22lastName%22%3A%22Loeffler%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Hans%22%2C%22lastName%22%3A%22Binder%22%7D%5D%2C%22abstractNote%22%3A%223D-body%20scanning%20anthropometry%20is%20a%20suitable%20method%20for%20characterization%20of%20physiological%20development%20of%20children%20and%20adolescents%2C%20and%20for%20understanding%20onset%20and%20progression%20of%20disorders%20like%20overweight%20and%20obesity.%20Here%20we%20present%20a%20novel%20body%20typing%20approach%20to%20describe%20and%20to%20interpret%20longitudinal%203D-body%20scanning%20data%20of%20more%20than%20800%20children%20and%20adolescents%20measured%20in%20up%20to%20four%20follow-ups%20in%20intervals%20of%201%20year%2C%20referring%20to%20an%20age%20range%20between%206%20and%2018%20years.%20We%20analyzed%20transitions%20between%20body%20types%20assigned%20to%20lower-%2C%20normal-%20and%20overweight%20participants%20upon%20development%20of%20children%20and%20adolescents.%20We%20found%20a%20virtually%20parallel%20development%20of%20the%20body%20types%20with%20only%20a%20few%20transitions%20between%20them.%20Body%20types%20of%20children%20and%20adolescents%20tend%20to%20conserve%20their%20weight%20category.%203D%20body%20scanning%20anthropometry%20in%20combination%20with%20body%20typing%20constitutes%20a%20novel%20option%20to%20investigate%20onset%20and%20progression%20of%20obesity%20in%20children.%22%2C%22date%22%3A%222018-09%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1371%5C%2Fjournal.pone.0203628%22%2C%22ISSN%22%3A%221932-6203%22%2C%22url%22%3A%2210.1371%5C%2Fjournal.pone.0203628%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-07T07%3A01%3A39Z%22%7D%7D%2C%7B%22key%22%3A%224MFC9N5Z%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Rocha%20et%20al.%22%2C%22parsedDate%22%3A%222018-09%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3ERocha%2C%20Edrienny%20Patr%26%23xED%3Bcia%20Alves%20Accioly%2C%20Mandy%20Vogel%2C%20Juraj%20Stanik%2C%20Diana%20Pietzner%2C%20Anja%20Willenberg%2C%20Antje%20K%26%23xF6%3Brner%2C%20and%20Wieland%20Kiess.%20%26%23x201C%3BSerum%20Uric%20Acid%20Levels%20as%20an%20Indicator%20for%20Metabolically%20Unhealthy%20Obesity%20in%20Children%20and%20Adolescents.%26%23x201D%3B%20%3Ci%3EHormone%20Research%20in%20Paediatrics%3C%5C%2Fi%3E%2090%2C%20no.%201%20%28September%202018%29%3A%2019%26%23×2013%3B27.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1159%5C%2F000490113%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1159%5C%2F000490113%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Serum%20Uric%20Acid%20Levels%20as%20an%20Indicator%20for%20Metabolically%20Unhealthy%20Obesity%20in%20Children%20and%20Adolescents%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Edrienny%20Patr%5Cu00edcia%20Alves%20Accioly%22%2C%22lastName%22%3A%22Rocha%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Juraj%22%2C%22lastName%22%3A%22Stanik%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Diana%22%2C%22lastName%22%3A%22Pietzner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anja%22%2C%22lastName%22%3A%22Willenberg%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%5D%2C%22abstractNote%22%3A%22%3Cb%3E%3Ci%3EBackground%3A%3C%5C%2Fi%3E%3C%5C%2Fb%3E%20Metabolically%20healthy%20obesity%20%28MHO%29%20refers%20to%20those%20individuals%20who%20do%20not%20show%20cardiometabolic%20abnormalities.%20Our%20aim%20was%20to%20identify%20potential%20clinical%20and%20metabolic%20indicators%20that%20may%20help%20to%20distinguish%20between%20metabolically%20healthy%20and%20unhealthy%20individuals%20amongst%20overweight%20and%20obese%20children%20and%20adolescents.%20%3Cb%3E%3Ci%3EMethods%3A%3C%5C%2Fi%3E%3C%5C%2Fb%3E%20The%20study%20involved%20246%20overweight%5C%2Fobese%20and%20212%20normal-weight%20individuals%20enrolled%20in%20the%20LIFE%20Child%20study%2C%20aged%20between%206%20and%2018%20years.%20Overweight%5C%2Fobese%20individuals%20without%20cardiovascular%20risk%20factors%20%28fasting%20serum%20lipids%2C%20blood%20pressure%2C%20and%20glucose%29%20were%20classified%20as%20MHO.%20Individuals%20meeting%201%20or%20more%20criteria%20of%20cardiovascular%20risk%20factors%20were%20classified%20as%20metabolically%20unhealthy%20obesity%20%28MUO%29.%20%3Cb%3E%3Ci%3EResults%3A%3C%5C%2Fi%3E%3C%5C%2Fb%3E%20Among%20the%20246%20overweight%5C%2Fobese%20individuals%2C%20173%20%2870%25%29%20were%20MHO%20and%2073%20%2830%25%29%20were%20MUO.%20The%20MHO%20individuals%20were%20younger%2C%20more%20likely%20to%20be%20male%2C%20and%20had%20lower%20BMI%20SDS.%20In%20the%20logistic%20regression%20models%2C%20uric%20acid%20%28UA%29%20SDS%20%28OR%201.61%2C%2095%25%20CI%201.1%5Cu20132.6%2C%20%3Ci%3Ep%3C%5C%2Fi%3E%20%3D%200.004%29%2C%20waist%20circumference%20SDS%20%28OR%202.50%2C%2095%25%20CI%201.2%5Cu20136.4%2C%20%3Ci%3Ep%3C%5C%2Fi%3E%20%3D%200.017%29%2C%20and%20C-peptide%20%28OR%204.05%2C%2095%25%20CI%203.5%5Cu201391%2C%20%3Ci%3Ep%3C%5C%2Fi%3E%20%3D%200.003%29%20were%20significant%20indicators%20of%20MUO.%20%3Cb%3E%3Ci%3EConclusion%3A%3C%5C%2Fi%3E%3C%5C%2Fb%3E%20Our%20results%20suggest%20that%20nearly%20one-third%20of%20overweight%5C%2Fobese%20children%20are%20already%20identified%20as%20MUO.%20Serum%20levels%20of%20UA%20can%20be%20used%20as%20an%20indicator%20of%20unhealthy%20obesity%20in%20youth%2C%20where%20lower%20levels%20of%20UA%20indicate%20a%20lower%20risk%20and%20higher%20levels%20suggest%20a%20higher%20risk%20of%20MUO.%20We%20note%20that%20the%20relevance%20of%20identifying%20potential%20indicators%20remains%20the%20first%20most%20important%20step%20in%20future%20clinical%20research.%22%2C%22date%22%3A%222018-09%22%2C%22language%22%3A%22english%22%2C%22DOI%22%3A%2210.1159%5C%2F000490113%22%2C%22ISSN%22%3A%221663-2818%2C%201663-2826%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.karger.com%5C%2FArticle%5C%2FFullText%5C%2F490113%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-24T11%3A15%3A10Z%22%7D%7D%2C%7B%22key%22%3A%22RJVND5C7%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Paech%20et%20al.%22%2C%22parsedDate%22%3A%222017-12-01%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EPaech%2C%20C.%2C%20A.%20Liebold%2C%20R.%20A.%20Gebauer%2C%20F.%20Wagner%2C%20M.%20Vogel%2C%20T.%20Kirsten%2C%20M.%20Schauff%2C%20et%20al.%20%26%23x201C%3BRelative%20Qt%20Interval%20Prolongation%20and%20Electrical%20Inhomogeneity%20of%20Cardiac%20Repolarization%20in%20Childhood%20Obesity.%26%23x201D%3B%20%3Ci%3EProgress%20in%20Pediatric%20Cardiology%3C%5C%2Fi%3E%2047%2C%20no.%20Supplement%20C%20%28December%201%2C%202017%29%3A%2064%26%23×2013%3B67.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.ppedcard.2017.08.001%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.ppedcard.2017.08.001%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Relative%20Qt%20Interval%20Prolongation%20and%20Electrical%20Inhomogeneity%20of%20Cardiac%20Repolarization%20in%20Childhood%20Obesity%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22C.%22%2C%22lastName%22%3A%22Paech%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22A.%22%2C%22lastName%22%3A%22Liebold%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22R.%20A.%22%2C%22lastName%22%3A%22Gebauer%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22F.%22%2C%22lastName%22%3A%22Wagner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22M.%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22T.%22%2C%22lastName%22%3A%22Kirsten%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22M.%22%2C%22lastName%22%3A%22Schauff%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22A.%22%2C%22lastName%22%3A%22Hiemisch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22I.%22%2C%22lastName%22%3A%22D%5Cu00e4hnert%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22W.%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22A.%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%5D%2C%22abstractNote%22%3A%22Studies%20in%20adults%20demonstrated%20an%20association%20of%20obesity%20with%20prolongation%20of%20cardiac%20repolarization%20and%20an%20increased%20risk%20of%20ventricular%20arrhythmia%20and%20sudden%20cardiac%20death.%20The%20aim%20of%20this%20study%20was%20to%20evaluate%20potential%20alterations%20in%20cardiac%20repolarization%20in%20obese%20children.%2083%20lean%20and%20132%20obese%20consecutive%20healthy%20pediatric%20volunteers%20from%20the%20LIFE%20Child%20Study%20cohort%20were%20prospectively%20enrolled%20and%20their%20ECGs%20were%20analyzed.%20There%20was%20a%20significant%20prolongation%20of%20corrected%20QT%20interval%20%28p%3D0.001%29%2C%20T%20peak-to-end%20%28p%3D0.001%29%20and%20QT%20dispersion%20%28p%3D0.001%29%20in%20obese%20compared%20to%20lean%20children.%20The%20QT%20interval%20prolongation%20was%20more%20pronounced%20in%20girls%20than%20in%20boys%20%28p%3D0.002%29%2C%20whereas%20there%20were%20no%20significant%20sex%20dependent%20differences%20in%20QT%20dispersion%20%28p%3D0.18%29%20or%20T%20peak-to-end%20%28p%3D0.39%29.%20Childhood%20obesity%20seems%20to%20be%20associated%20with%20a%20cardiac%20electrical%20inhomogeneity%20with%20the%20hypothetical%20potential%20for%20an%20increased%20arrhythmogenic%20risk.%20Furthermore%2C%20it%20causes%20a%20relative%20prolongation%20of%20the%20QTc%20interval%20compared%20to%20lean%20children%20with%20a%20more%20evident%20effect%20in%20females%2C%20yet%20without%20prolongation%20beyond%20the%20upper%20limits%20of%20normal.%22%2C%22date%22%3A%22December%201%2C%202017%22%2C%22language%22%3A%22%22%2C%22DOI%22%3A%2210.1016%5C%2Fj.ppedcard.2017.08.001%22%2C%22ISSN%22%3A%221058-9813%22%2C%22url%22%3A%22http%3A%5C%2F%5C%2Fwww.sciencedirect.com%5C%2Fscience%5C%2Farticle%5C%2Fpii%5C%2FS1058981317300620%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-07T07%3A01%3A36Z%22%7D%7D%2C%7B%22key%22%3A%22GN3QB753%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Kess%20et%20al.%22%2C%22parsedDate%22%3A%222017-12%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EKess%2C%20Annette%2C%20Ulrike%20Spielau%2C%20Christoph%20Beger%2C%20Ruth%20Gausche%2C%20Mandy%20Vogel%2C%20Tobias%20Lipek%2C%20Antje%20K%26%23xF6%3Brner%2C%20Roland%20Pf%26%23xE4%3Bffle%2C%20and%20Wieland%20Kiess.%20%26%23x201C%3BFurther%20Stabilization%20and%20Even%20Decrease%20in%20the%20Prevalence%20Rates%20of%20Overweight%20and%20Obesity%20in%20German%20Children%20and%20Adolescents%20from%202005%20to%202015%3A%20A%20Cross-Sectional%20and%20Trend%20Analysis.%26%23x201D%3B%20%3Ci%3EPublic%20Health%20Nutrition%3C%5C%2Fi%3E%2020%2C%20no.%2017%20%28December%202017%29%3A%203075%26%23×2013%3B83.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1017%5C%2FS1368980017002257%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1017%5C%2FS1368980017002257%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Further%20Stabilization%20and%20Even%20Decrease%20in%20the%20Prevalence%20Rates%20of%20Overweight%20and%20Obesity%20in%20German%20Children%20and%20Adolescents%20from%202005%20to%202015%3A%20A%20Cross-Sectional%20and%20Trend%20Analysis%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Annette%22%2C%22lastName%22%3A%22Kess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ulrike%22%2C%22lastName%22%3A%22Spielau%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christoph%22%2C%22lastName%22%3A%22Beger%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ruth%22%2C%22lastName%22%3A%22Gausche%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tobias%22%2C%22lastName%22%3A%22Lipek%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Roland%22%2C%22lastName%22%3A%22Pf%5Cu00e4ffle%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%5D%2C%22abstractNote%22%3A%22OBJECTIVE%3A%20Recently%20several%20industrialized%20countries%20reported%20a%20stabilization%20or%20even%20a%20decrease%20in%20childhood%20overweight%20and%20obesity%20prevalence%20rates.%20In%20Germany%2C%20this%20trend%20started%20in%202004.%20The%20present%20study%20therefore%20aimed%20to%20evaluate%20whether%20this%20trend%20has%20continued%20or%20even%20leads%20in%20a%20clear%20direction.%20Design%5C%2FSetting%5C%2FSubjects%20BMI%20%28%3E90th%20percentile%20%28overweight%29%2C%20%3E97th%20percentile%20%28obesity%29%29%20from%20the%20CrescNet%20database%20was%20analysed%20in%20326%20834%20children%20and%20adolescents%20according%20to%20three%20age%20groups%20%284-7%5Cu00b799%2C%208-11%5Cu00b799%20and%2012-16%20years%29%2C%20gender%20and%20between%20time%20points%20%282005-2015%29.%5CnRESULTS%3A%20Trend%20analysis%20from%202005%20to%202010%20demonstrated%20that%20the%20prevalence%20of%20overweight%20and%20obesity%20decreased%20significantly%20in%20boys%20and%20girls%20in%20the%20entire%20group%20%284-16%20years%29%20and%20in%204-7%5Cu00b799-year-olds.%20From%202010%20to%202015%20there%20was%20a%20significant%20decrease%20in%20boys%20for%20overweight%20and%20obesity%20in%20the%20entire%20group%20and%20for%20overweight%20among%208-11%5Cu00b799-year-olds.%20Within%20the%20cross-sectional%20analysis%2C%20prevalence%20rates%20for%20overweight%20decreased%20significantly%20for%20both%20genders%20in%20the%20age%20groups%20of%204-7%5Cu00b799%20and%208-11%5Cu00b799%20years%20%282005%20v.%202015%29.%20For%20obesity%2C%20prevalence%20rates%20showed%20a%20significant%20decrease%20for%20boys%20%282005%20v.%202015%29%20and%20girls%20%282005%20v.%202010%29%20in%204-7%5Cu00b799-year-olds.%5CnCONCLUSIONS%3A%20We%20observed%20a%20further%20stabilization%20of%20overweight%20and%20obesity%20prevalence%20rates%20for%20all%20age%20groups%20and%20even%20a%20decrease%20in%20the%20rates%20for%20the%20younger%20ages%20%284-7%5Cu00b799%20years%2C%208-11%5Cu00b799%20years%29.%20As%20other%20industrialized%20countries%20have%20also%20reported%20similar%20trends%2C%20it%20seems%20that%20the%20epidemic%20of%20childhood%20overweight%20and%20obesity%20is%20reaching%20a%20turning%20point%20in%20the%20industrial%20part%20of%20the%20world.%22%2C%22date%22%3A%22December%202017%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1017%5C%2FS1368980017002257%22%2C%22ISSN%22%3A%221475-2727%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-12-30T09%3A24%3A35Z%22%7D%7D%2C%7B%22key%22%3A%22IJI97JMV%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Loeffler-Wirth%20et%20al.%22%2C%22parsedDate%22%3A%222017-10%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3ELoeffler-Wirth%2C%20Henry%2C%20Mandy%20Vogel%2C%20Toralf%20Kirsten%2C%20Fabian%20Glock%2C%20Tanja%20Poulain%2C%20Antje%20K%26%23xF6%3Brner%2C%20Markus%20Loeffler%2C%20Wieland%20Kiess%2C%20and%20Hans%20Binder.%20%26%23x201C%3BBody%20Typing%20of%20Children%20and%20Adolescents%20Using%203d-Body%20Scanning.%26%23x201D%3B%20%3Ci%3EPloS%20One%3C%5C%2Fi%3E%2012%2C%20no.%2010%20%28October%202017%29%3A%20e0186881.%20https%3A%5C%2F%5C%2Fdoi.org%5C%2F%3Ca%20class%3D%27zp-ItemURL%27%20target%3D%27_blank%27%20href%3D%2710.1371%5C%2Fjournal.pone.0186881%27%3E10.1371%5C%2Fjournal.pone.0186881%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Body%20Typing%20of%20Children%20and%20Adolescents%20Using%203d-Body%20Scanning%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Henry%22%2C%22lastName%22%3A%22Loeffler-Wirth%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Toralf%22%2C%22lastName%22%3A%22Kirsten%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Fabian%22%2C%22lastName%22%3A%22Glock%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Markus%22%2C%22lastName%22%3A%22Loeffler%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Hans%22%2C%22lastName%22%3A%22Binder%22%7D%5D%2C%22abstractNote%22%3A%22Three-dimensional%20%283D-%29%20body%20scanning%20of%20children%20and%20adolescents%20allows%20the%20detailed%20study%20of%20physiological%20development%20in%20terms%20of%20anthropometrical%20alterations%20which%20potentially%20provide%20early%20onset%20markers%20for%20obesity.%20Here%2C%20we%20present%20a%20systematic%20analysis%20of%20body%20scanning%20data%20of%202%2C700%20urban%20children%20and%20adolescents%20in%20the%20age%20range%20between%205%20and%2018%20years%20with%20the%20special%20aim%20to%20stratify%20the%20participants%20into%20distinct%20body%20shape%20types%20and%20to%20describe%20their%20change%20upon%20development.%20In%20a%20first%20step%2C%20we%20extracted%20a%20set%20of%20eight%20representative%20meta-measures%20from%20the%20data.%20Each%20of%20them%20collects%20a%20related%20group%20of%20anthropometrical%20features%20and%20changes%20specifically%20upon%20aging.%20In%20a%20second%20step%20we%20defined%20seven%20body%20types%20by%20clustering%20the%20meta-measures%20of%20all%20participants.%20These%20body%20types%20describe%20the%20body%20shapes%20in%20terms%20of%20three%20weight%20%28lower%2C%20normal%20and%20overweight%29%20and%20three%20age%20%28young%2C%20medium%20and%20older%29%20categories.%20For%20younger%20children%20%28age%20of%205-10%20years%29%20we%20found%20a%20common%20%27early%20childhood%20body%20shape%27%20which%20splits%20into%20three%20weight-dependent%20types%20for%20older%20children%2C%20with%20one%20or%20two%20years%20delay%20for%20boys.%20Our%20study%20shows%20that%20the%20concept%20of%20body%20types%20provides%20a%20reliable%20option%20for%20the%20anthropometric%20characterization%20of%20developing%20and%20aging%20populations.%22%2C%22date%22%3A%222017-10%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1371%5C%2Fjournal.pone.0186881%22%2C%22ISSN%22%3A%221932-6203%22%2C%22url%22%3A%2210.1371%5C%2Fjournal.pone.0186881%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-24T09%3A25%3A53Z%22%7D%7D%2C%7B%22key%22%3A%22ATVGL5IF%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Junge%20et%20al.%22%2C%22parsedDate%22%3A%222017-05%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EJunge%2C%20Jennifer%2C%20Christoph%20Engel%2C%20Mandy%20Vogel%2C%20Stephanie%20Naumann%2C%20Markus%20L%26%23xF6%3Bffler%2C%20Joachim%20Thiery%2C%20J%26%23xFC%3Brgen%20Kratzsch%2C%20Wieland%20Kiess%2C%20and%20Antje%20K%26%23xF6%3Brner.%20%26%23x201C%3BNeck%20Circumference%20Is%20Similarly%20Predicting%20for%20Impairment%20of%20Glucose%20Tolerance%20as%20Classic%20Anthropometric%20Parameters%20Among%20Healthy%20and%20Obese%20Children%20and%20Adolescents.%26%23x201D%3B%20%3Ci%3EJournal%20of%20Pediatric%20Endocrinology%20and%20Metabolism%3C%5C%2Fi%3E%2030%2C%20no.%206%20%28May%202017%29%3A%20643%26%23×2013%3B50.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1515%5C%2Fjpem-2017-0079%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1515%5C%2Fjpem-2017-0079%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Neck%20Circumference%20Is%20Similarly%20Predicting%20for%20Impairment%20of%20Glucose%20Tolerance%20as%20Classic%20Anthropometric%20Parameters%20Among%20Healthy%20and%20Obese%20Children%20and%20Adolescents%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jennifer%22%2C%22lastName%22%3A%22Junge%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christoph%22%2C%22lastName%22%3A%22Engel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Stephanie%22%2C%22lastName%22%3A%22Naumann%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Markus%22%2C%22lastName%22%3A%22L%5Cu00f6ffler%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Joachim%22%2C%22lastName%22%3A%22Thiery%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J%5Cu00fcrgen%22%2C%22lastName%22%3A%22Kratzsch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%5D%2C%22abstractNote%22%3A%22Background%3A%5CnThe%20objective%20of%20the%20study%20was%20to%20investigate%20the%20association%20of%20neck%20circumference%20%28NC%29%20to%20parameters%20of%20glucose%20homeostasis%20compared%20to%20classical%20anthropometric%20parameters%20of%20lean%20and%20obese%20children.%5CnMethods%3A%5CnThree%20dimensional%20%283D%29-body%20scanning%20quantified%20anthropometric%20%28height%2C%20weight%2C%20NC%2C%20hip%5C%2Fwaist%20circumference%2C%20BMI%29%20and%20metabolic%20parameters%20%28fasting%20plasma%20glucose%20%5BFPG%5D%2C%20insulin%2C%20HbA1c%2C%20oGTT%2C%20HOMA-IR%29%20were%20determined%20cross-sectionally%20in%201542%20participants%20%285%5Cu201318%20years%29.%5CnResults%3A%5CnNC%20was%20positively%20correlated%20with%20all%20metabolic%20parameters%2C%20except%20for%20FPG.%20For%20HbA1c%20there%20was%20only%20a%20modestly%20positive%20correlation.%20The%20associations%20between%20NC%20and%20glucose%20parameters%20were%20rather%20weak%2C%20while%20the%20correlation%20to%20insulin%20parameters%20were%20stronger.%20Overall%20the%20strongest%20association%20to%20glucose%20metabolism%20parameters%20was%20found%20for%20waist%20circumference%20%28WC%29%2C%20except%20for%20FPG%20and%202h-postload%20glucose.%20In%20multiple%20linear%20regression%20analyses%2C%20NC%20provided%20additional%20benefit%20beyond%20classical%20anthropometric%20indices%20to%20describe%20impairment%20of%20glucose%20homeostasis.%5CnConclusions%3A%5CnWe%20suggest%20that%20NC%20is%20comparable%20or%20additive%20to%20established%20anthropometric%20parameters%20but%20might%20not%20be%20superior%20to%20them.%20However%20NC%20is%20simple%20to%20measure%2C%20reproducible%20and%20may%20be%20considered%20in%20clinical%20practice%20as%20an%20additional%20measurement%20tool.%22%2C%22date%22%3A%222017-05%22%2C%22language%22%3A%22%22%2C%22DOI%22%3A%2210.1515%5C%2Fjpem-2017-0079%22%2C%22ISSN%22%3A%220334-018X%22%2C%22url%22%3A%22http%3A%5C%2F%5C%2Fwww.degruyter.com%5C%2Fview%5C%2Fj%5C%2Fjpem.2017.30.issue-6%5C%2Fjpem-2017-0079%5C%2Fjpem-2017-0079.xml%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-07T07%3A01%3A43Z%22%7D%7D%2C%7B%22key%22%3A%22DLYPDILR%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Bussler%20et%20al.%22%2C%22parsedDate%22%3A%222017%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EBussler%2C%20Sarah%2C%20Melanie%20Penke%2C%20Gunter%20Flemming%2C%20Yasir%20S.%20Elhassan%2C%20J%26%23xFC%3Brgen%20Kratzsch%2C%20Elena%20Sergeyev%2C%20Tobias%20Lipek%2C%20et%20al.%20%26%23x201C%3BNovel%20Insights%20in%20the%20Metabolic%20Syndrome%20in%20Childhood%20and%20Adolescence.%26%23x201D%3B%20%3Ci%3EHormone%20Research%20in%20Paediatrics%3C%5C%2Fi%3E%2088%2C%20no.%203%26%23×2013%3B4%20%282017%29%3A%20181%26%23×2013%3B93.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1159%5C%2F000479510%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1159%5C%2F000479510%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Novel%20Insights%20in%20the%20Metabolic%20Syndrome%20in%20Childhood%20and%20Adolescence%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Sarah%22%2C%22lastName%22%3A%22Bussler%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Melanie%22%2C%22lastName%22%3A%22Penke%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Gunter%22%2C%22lastName%22%3A%22Flemming%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Yasir%20S.%22%2C%22lastName%22%3A%22Elhassan%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J%5Cu00fcrgen%22%2C%22lastName%22%3A%22Kratzsch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Elena%22%2C%22lastName%22%3A%22Sergeyev%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tobias%22%2C%22lastName%22%3A%22Lipek%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ulrike%22%2C%22lastName%22%3A%22Spielau%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tommaso%22%2C%22lastName%22%3A%22de%5Cu00a0Giorgis%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%5D%2C%22abstractNote%22%3A%22Metabolic%20syndrome%20%28MetS%29%20is%20recognized%20as%20an%20escalating%20major%20health%20risk%20in%20adults%20as%20well%20as%20in%20children%20and%20adolescents.%20Its%20prevalence%20ranges%20from%206%20to%2039%25%20depending%20on%20the%20applied%20definition%20cri%22%2C%22date%22%3A%222017%22%2C%22language%22%3A%22english%22%2C%22DOI%22%3A%2210.1159%5C%2F000479510%22%2C%22ISSN%22%3A%221663-2818%2C%201663-2826%22%2C%22url%22%3A%22http%3A%5C%2F%5C%2Fwww.karger.com%5C%2FArticle%5C%2FFullText%5C%2F479510%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-23T10%3A55%3A37Z%22%7D%7D%2C%7B%22key%22%3A%227MBJ4H72%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Schreier%20et%20al.%22%2C%22parsedDate%22%3A%222016-11%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3ESchreier%2C%20Moritz%2C%20Julian%20Tristan%20Schwartze%2C%20Kathrin%20Landgraf%2C%20Kathrin%20Scheuermann%2C%20Sandra%20Erbs%2C%20Gunda%20Herberth%2C%20J.%20Andrew%20Pospisilik%2C%20J%26%23xFC%3Brgen%20Kratzsch%2C%20Wieland%20Kiess%2C%20and%20Antje%20K%26%23xF6%3Brner.%20%26%23x201C%3BOsteopontin%20Is%20Bmi-Independently%20Related%20to%20Early%20Endothelial%20Dysfunction%20in%20Children.%26%23x201D%3B%20%3Ci%3EJournal%20of%20Pediatric%20Endocrinology%20and%20Metabolism%3C%5C%2Fi%3E%20101%2C%20no.%2011%20%28November%202016%29%3A%204161%26%23×2013%3B69.%20%3Ca%20class%3D%27zp-ItemURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1210%5C%2Fjc.2016-2238%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1210%5C%2Fjc.2016-2238%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Osteopontin%20Is%20Bmi-Independently%20Related%20to%20Early%20Endothelial%20Dysfunction%20in%20Children%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Moritz%22%2C%22lastName%22%3A%22Schreier%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Julian%20Tristan%22%2C%22lastName%22%3A%22Schwartze%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Kathrin%22%2C%22lastName%22%3A%22Landgraf%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Kathrin%22%2C%22lastName%22%3A%22Scheuermann%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Sandra%22%2C%22lastName%22%3A%22Erbs%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Gunda%22%2C%22lastName%22%3A%22Herberth%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J.%20Andrew%22%2C%22lastName%22%3A%22Pospisilik%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J%5Cu00fcrgen%22%2C%22lastName%22%3A%22Kratzsch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%5D%2C%22abstractNote%22%3A%22%22%2C%22date%22%3A%222016-11%22%2C%22language%22%3A%22%22%2C%22DOI%22%3A%2210.1210%5C%2Fjc.2016-2238%22%2C%22ISSN%22%3A%22%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1210%5C%2Fjc.2016-2238%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-07T07%3A01%3A25Z%22%7D%7D%2C%7B%22key%22%3A%22NXK52B65%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Landgraf%20et%20al.%22%2C%22parsedDate%22%3A%222016-08%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3ELandgraf%2C%20Kathrin%2C%20Markus%20Scholz%2C%20Peter%20Kovacs%2C%20Wieland%20Kiess%2C%20and%20Antje%20K%26%23xF6%3Brner.%20%26%23x201C%3BFTO%20Obesity%20Risk%20Variants%20Are%20Linked%20to%20Adipocyte%20IRX3%20Expression%20and%20BMI%20of%20Children%20-%20Relevance%20of%20FTO%20Variants%20to%20Defend%20Body%20Weight%20in%20Lean%20Children%3F%26%23x201D%3B%20%3Ci%3EPLOS%20ONE%3C%5C%2Fi%3E%2011%2C%20no.%208%20%28August%202016%29%3A%20e0161739.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1371%5C%2Fjournal.pone.0161739%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1371%5C%2Fjournal.pone.0161739%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22FTO%20Obesity%20Risk%20Variants%20Are%20Linked%20to%20Adipocyte%20IRX3%20Expression%20and%20BMI%20of%20Children%20-%20Relevance%20of%20FTO%20Variants%20to%20Defend%20Body%20Weight%20in%20Lean%20Children%3F%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Kathrin%22%2C%22lastName%22%3A%22Landgraf%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Markus%22%2C%22lastName%22%3A%22Scholz%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Peter%22%2C%22lastName%22%3A%22Kovacs%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%5D%2C%22abstractNote%22%3A%22Background%20Genome-wide%20association%20studies%20have%20identified%20variants%20within%20the%20FTO%20%28fat%20mass%20and%20obesity%20associated%29%20locus%20as%20the%20strongest%20predictors%20of%20obesity%20amongst%20all%20obesity-associated%20gene%20loci.%20Recent%20evidence%20suggests%20that%20variants%20in%20FTO%20directly%20affect%20human%20adipocyte%20function%20through%20targeting%20IRX3%20and%20IRX5%20and%20thermogenesis%20regulation.%20Aim%20We%20addressed%20the%20relevance%20of%20this%20proposed%20FTO-IRX%20pathway%20in%20adipose%20tissue%20%28AT%29%20of%20children.%20Results%20Expression%20of%20IRX3%20was%20higher%20in%20adipocytes%20compared%20to%20SVF.%20We%20found%20increased%20adipocyte-specific%20expression%20of%20IRX3%20and%20IRX5%20with%20the%20presence%20of%20the%20FTO%20risk%20haplotype%20in%20lean%20children%2C%20whereas%20it%20was%20unaffected%20by%20risk%20variants%20in%20obese%20peers.%20We%20further%20show%20that%20IRX3%20expression%20was%20elevated%20in%20isolated%20adipocytes%20and%20AT%20of%20lean%20compared%20to%20obese%20children%2C%20particularly%20in%20UCP1-negative%20adipocytes%2C%20and%20inversely%20correlated%20with%20BMI%20SDS.%20Independent%20of%20BMI%2C%20IRX3%20expression%20in%20adipocytes%20was%20significantly%20related%20to%20adipocyte%20hypertrophy%2C%20and%20subsequent%20associations%20with%20AT%20inflammation%20and%20HOMA-IR%20in%20the%20children.%20Conclusion%20One%20interpretation%20of%20our%20observation%20of%20FTO%20risk%20variants%20linked%20to%20IRX3%20expression%20and%20adipocyte%20size%20restricted%20to%20lean%20children%2C%20along%20with%20the%20decreased%20IRX3%20expression%20in%20obese%20compared%20to%20lean%20peers%2C%20may%20reflect%20a%20defense%20mechanism%20for%20protecting%20body-weight%2C%20which%20is%20pertinent%20for%20lean%20children.%22%2C%22date%22%3A%22August%2C%202016%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1371%5C%2Fjournal.pone.0161739%22%2C%22ISSN%22%3A%221932-6203%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fjournals.plos.org%5C%2Fplosone%5C%2Farticle%3Fid%3D10.1371%5C%2Fjournal.pone.0161739%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-24T09%3A17%3A35Z%22%7D%7D%2C%7B%22key%22%3A%22D36JFJIJ%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Sonnengr%5Cu00fcn%20et%20al.%22%2C%22parsedDate%22%3A%222016-06%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3ESonnengr%26%23xFC%3Bn%2C%20Lilli%2C%20Celestina%20Schober%2C%20Mandy%20Vogel%2C%20Andreas%20Hiemisch%2C%20Mirko%20D%26%23xF6%3Bhnert%2C%20Anja%20Hilbert%2C%20and%20Wieland%20Kiess.%20%26%23x201C%3BFeeding%2C%20Eating%20and%20Behavioral%20Disturbances%20in%20Prader-Willi%20Syndrome%20and%20Non-Syndromal%20Obesity.%26%23x201D%3B%20%3Ci%3EJournal%20of%20Pediatric%20Endocrinology%20and%20Metabolism%3C%5C%2Fi%3E%2029%2C%20no.%208%20%28June%202016%29%3A%20923%26%23×2013%3B32.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1515%5C%2Fjpem-2016-0085%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1515%5C%2Fjpem-2016-0085%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Feeding%2C%20Eating%20and%20Behavioral%20Disturbances%20in%20Prader-Willi%20Syndrome%20and%20Non-Syndromal%20Obesity%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Lilli%22%2C%22lastName%22%3A%22Sonnengr%5Cu00fcn%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Celestina%22%2C%22lastName%22%3A%22Schober%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andreas%22%2C%22lastName%22%3A%22Hiemisch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mirko%22%2C%22lastName%22%3A%22D%5Cu00f6hnert%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anja%22%2C%22lastName%22%3A%22Hilbert%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%5D%2C%22abstractNote%22%3A%22Background%3A%5Cn%5CnAlthough%20most%20individuals%20with%20Prader-Willi%20syndrome%20%28PWS%29%20are%20obese%2C%20little%20is%20known%20about%20the%20impact%20of%20obesity-related%20psychosocial%20factors%20in%20PWS.%20In%20the%20present%20study%20we%20compared%20feeding%2C%20eating%2C%20and%20behavioral%20disturbances%20in%20children%20and%20adolescents%20with%20PWS%2C%20peers%20with%20non-syndromal%20obesity%2C%20and%20normal%20weight%20controls.%5CnMethods%3A%5Cn%5CnTwelve%20persons%20with%20PWS%2C%20aged%207%5Cu201322%20years%2C%20age-%20and%20gender-matched%20obese%20and%20normal%20weight%20individuals%20were%20analyzed%20regarding%20parental%20feeding%20practices%2C%20eating%20disturbances%2C%20and%20behavioral%20problems%20via%20standardized%20questionnaires.%5CnResults%3A%5Cn%5CnParents%20of%20individuals%20with%20PWS%20reported%20significantly%20more%20restrictive%20feeding%20and%20monitoring%20than%20did%20parents%20of%20obese%20or%20normal%20weight%20children%20without%20PWS%20%28p%3C0.05%29.%20Social%20problems%20were%20more%20common%20in%20the%20obese%20and%20the%20PWS%20group%20than%20in%20the%20normal-weight%20group%20%28p%3C0.05%29.%20Behavioral%20problems%20were%20significantly%20correlated%20with%20parental%20restrictive%20feeding%20practices.%5CnConclusions%3A%5Cn%5CnOur%20data%20show%20that%20children%20and%20adolescents%20with%20PWS%20are%20affected%20by%20psychosocial%20problems%2C%20and%20that%20restrictive%20feeding%20practices%20might%20be%20associated%20with%20more%20severe%20behavioral%20problems.%20Further%20studies%20in%20larger%20samples%20will%20be%20necessary%20to%20replicate%20these%20results%20and%20possibly%20provide%20new%20therapeutic%20approaches%20for%20the%20management%20of%20PWS.%22%2C%22date%22%3A%222016-06%22%2C%22language%22%3A%22%22%2C%22DOI%22%3A%2210.1515%5C%2Fjpem-2016-0085%22%2C%22ISSN%22%3A%220334-018X%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.degruyter.com%5C%2Fview%5C%2Fj%5C%2Fjpem.2016.29.issue-8%5C%2Fjpem-2016-0085%5C%2Fjpem-2016-0085.xml%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-24T13%3A13%3A32Z%22%7D%7D%2C%7B%22key%22%3A%22G9T2XXHI%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Gram%5Cu00df%20et%20al.%22%2C%22parsedDate%22%3A%222016%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EGram%26%23xDF%3B%2C%20Manuela%2C%20Andreas%20Hiemisch%2C%20and%20Wieland%20Kiess.%20%26%23x201C%3BStellt%20%26%23xDC%3Bbergewicht%20ein%20Risiko%20f%26%23xFC%3Br%20die%20Entwicklung%20von%20Asthma%20bronchiale%20im%20Kindes-%20und%20Jugendalter%20dar%3F%26%23x201D%3B%20%3Ci%3EAdipositas%20-%20Ursachen%2C%20Folgeerkrankungen%2C%20Therapie%3C%5C%2Fi%3E%2010%2C%20no.%202%20%282016%29%3A%2088%26%23×2013%3B92.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1055%5C%2Fs-0037-1617702%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1055%5C%2Fs-0037-1617702%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Stellt%20%5Cu00dcbergewicht%20ein%20Risiko%20f%5Cu00fcr%20die%20Entwicklung%20von%20Asthma%20bronchiale%20im%20Kindes-%20und%20Jugendalter%20dar%3F%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Manuela%22%2C%22lastName%22%3A%22Gram%5Cu00df%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andreas%22%2C%22lastName%22%3A%22Hiemisch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%5D%2C%22abstractNote%22%3A%22In%20den%20letzten%20beiden%20Jahrzehnten%20stiegen%20die%20Pr%5Cu00e4valenzen%20von%20Asthma%20bronchiale%20und%20%5Cu00dcbergewicht%20parallel%20an.%20F%5Cu00fcr%20beide%20Erkrankungen%20werden%20%5Cu00e4hnliche%20Ursachen%20diskutiert%3A%20umweltbezogene%2C%20genetische%2C%20sozio%5Cu00f6konomische%20Faktoren%20und%20sogar%20die%20Einflussnahme%20durch%20Adipokine.%20Au%5Cu00dferdem%20r%5Cu00fcckte%20das%20%5Cu00dcbergewicht%20als%20potenzieller%20Ausl%5Cu00f6ser%20und%20beg%5Cu00fcnstigender%20Faktor%20von%20Asthma%20bronchiale%20in%20den%20Fokus%20der%20Forschung.%20Der%20BMI%20ist%20sowohl%20mit%20der%20Diagnose%20Asthma%20als%20auch%20mit%20dem%20Symptom%20%5Cu201ewheezing%5Cu201d%20positiv%20korreliert.%20%5Cu00dcbergewichtige%20Kinder%20weisen%20gr%5Cu00f6%5Cu00dfere%20IgESpiegel%20und%20h%5Cu00e4ufiger%20Atopien%20auf.%20Jedoch%20zeigen%20Kinder%20mit%20gr%5Cu00f6%5Cu00dferem%20BMI%20h%5Cu00e4ufiger%20nichtatopisches%20als%20atopisches%20Asthma%20bronchiale.%20Zudem%20sind%20allergische%20Tests%20wie%20bronchiale%20Hyperreagibilit%5Cu00e4t%20und%20Skin%20Prick%20Tests%20bei%20adip%5Cu00f6sen%20Kindern%20nicht%20h%5Cu00e4ufiger%20positiv%20als%20bei%20normalgewichtigen%20Kindern.%20Die%20Lungenfunktionswerte%20bei%20%5Cu00dcbergewicht%20werden%20h%5Cu00e4ufig%20als%20Minderung%20des%20Tiffeneau-Index%20%28FEV1%5C%2FFVK%29%20beschrieben.%20Allerdings%20ist%20auch%20hier%20der%20Zusammenhang%20noch%20unklar%2C%20vor%20allem%20die%20Reaktion%20adip%5Cu00f6ser%20Kinder%20auf%20medikament%5Cu00f6se%20Broncholyse%20als%20Bestandteil%20der%20Spirometrie-Testung.%20Die%20nicht%20durchg%5Cu00e4ngig%20einheitlichen%20und%20teilweise%20nicht%20signifikanten%20Studienergebnisse%20lassen%20daher%20nicht%20auf%20eine%20unmittelbare%20Verbindung%20von%20Asthma%20und%20Adipositas%20oder%20auf%20den%20Einfluss%20von%20Kovariablen%20auf%20deren%20Verh%5Cu00e4ltnis%20schlie%5Cu00dfen.%20Die%20LIFE%20Child-Kohorte%20soll%20zur%20Kl%5Cu00e4rung%20offener%20Fragen%20beitragen.%22%2C%22date%22%3A%222016%22%2C%22language%22%3A%22de%22%2C%22DOI%22%3A%2210.1055%5C%2Fs-0037-1617702%22%2C%22ISSN%22%3A%221865-1739%2C%202567-6334%22%2C%22url%22%3A%22http%3A%5C%2F%5C%2Fwww.thieme-connect.de%5C%2FDOI%5C%2FDOI%3F10.1055%5C%2Fs-0037-1617702%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-07T07%3A01%3A46Z%22%7D%7D%2C%7B%22key%22%3A%22S5ZBNIFX%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Penke%20et%20al.%22%2C%22parsedDate%22%3A%222015-09-05%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EPenke%2C%20Melanie%2C%20Per%20S.%20Larsen%2C%20Susanne%20Schuster%2C%20Morten%20Dall%2C%20Benjamin%20A.%20H.%20Jensen%2C%20Theresa%20Gorski%2C%20Andrej%20Meusel%2C%20et%20al.%20%26%23x201C%3BHepatic%20Nad%20Salvage%20Pathway%20Is%20Enhanced%20in%20Mice%20on%20a%20High-Fat%20Diet.%26%23x201D%3B%20%3Ci%3EMolecular%20and%20Cellular%20Endocrinology%3C%5C%2Fi%3E%20412%20%28September%205%2C%202015%29%3A%2065%26%23×2013%3B72.%20https%3A%5C%2F%5C%2Fdoi.org%5C%2F%3Ca%20class%3D%27zp-ItemURL%27%20target%3D%27_blank%27%20href%3D%2710.1016%5C%2Fj.mce.2015.05.028%27%3E10.1016%5C%2Fj.mce.2015.05.028%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Hepatic%20Nad%20Salvage%20Pathway%20Is%20Enhanced%20in%20Mice%20on%20a%20High-Fat%20Diet%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Melanie%22%2C%22lastName%22%3A%22Penke%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Per%20S.%22%2C%22lastName%22%3A%22Larsen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Susanne%22%2C%22lastName%22%3A%22Schuster%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Morten%22%2C%22lastName%22%3A%22Dall%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Benjamin%20A.%20H.%22%2C%22lastName%22%3A%22Jensen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Theresa%22%2C%22lastName%22%3A%22Gorski%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andrej%22%2C%22lastName%22%3A%22Meusel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Sandy%22%2C%22lastName%22%3A%22Richter%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Sara%20G.%22%2C%22lastName%22%3A%22Vienberg%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jonas%20T.%22%2C%22lastName%22%3A%22Treebak%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22Garten%22%7D%5D%2C%22abstractNote%22%3A%22Nicotinamide%20phosphoribosyltransferase%20%28Nampt%29%20is%20the%20rate-limiting%20enzyme%20for%20NAD%20salvage%20and%20the%20abundance%20of%20Nampt%20has%20been%20shown%20to%20be%20altered%20in%20non-alcoholic%20fatty%20liver%20disease.%20It%20is%2C%20however%2C%20unknown%20how%20hepatic%20Nampt%20is%20regulated%20in%20response%20to%20accumulation%20of%20lipids%20in%20the%20liver%20of%20mice%20fed%20a%20high-fat%20diet%20%28HFD%29.%20HFD%20mice%20gained%20more%20weight%2C%20stored%20more%20hepatic%20lipids%20and%20had%20an%20impaired%20glucose%20tolerance%20compared%20with%20control%20mice.%20NAD%20levels%20as%20well%20as%20Nampt%20mRNA%20expression%2C%20protein%20abundance%20and%20activity%20were%20significantly%20increased%20in%20HFD%20mice.%20Enhanced%20NAD%20levels%20were%20associated%20with%20deacetylation%20of%20p53%20and%20Nf%5Cu03bab%20indicating%20increased%20activation%20of%20Sirt1.%20Despite%20impaired%20glucose%20tolerance%20and%20increased%20hepatic%20lipid%20levels%20in%20HFD%20mice%2C%20NAD%20metabolism%20was%20significantly%20enhanced.%20Thus%2C%20improved%20NAD%20metabolism%20may%20be%20a%20compensatory%20mechanism%20to%20protect%20against%20negative%20impact%20of%20hepatic%20lipid%20accumulation.%22%2C%22date%22%3A%22September%205%2C%202015%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1016%5C%2Fj.mce.2015.05.028%22%2C%22ISSN%22%3A%221872-8057%22%2C%22url%22%3A%2210.1016%5C%2Fj.mce.2015.05.028%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-24T10%3A43%3A40Z%22%7D%7D%2C%7B%22key%22%3A%22RPURNJGN%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Kiess%20et%20al.%22%2C%22parsedDate%22%3A%222011-05%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EKiess%2C%20Wieland%2C%20Elena%20Sergejev%2C%20Antje%20K%26%23xF6%3Brner%2C%20and%20Johannes%20Hebebrand.%20%26%23x201C%3BIst%20eine%20Therapie%20der%20Adipositas%20im%20Kindes-%20und%20Jugendalter%20%26%23xFC%3Bberhaupt%20m%26%23xF6%3Bglich%3F%26%23x201D%3B%20%3Ci%3EBundesgesundheitsblatt%20-%20Gesundheitsforschung%20-%20Gesundheitsschutz%3C%5C%2Fi%3E%2054%2C%20no.%205%20%28May%202011%29%3A%20527%26%23×2013%3B32.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs00103-011-1265-6%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs00103-011-1265-6%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Ist%20eine%20Therapie%20der%20Adipositas%20im%20Kindes-%20und%20Jugendalter%20%5Cu00fcberhaupt%20m%5Cu00f6glich%3F%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Elena%22%2C%22lastName%22%3A%22Sergejev%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Johannes%22%2C%22lastName%22%3A%22Hebebrand%22%7D%5D%2C%22abstractNote%22%3A%22Die%20Frage%2C%20ob%20eine%20Behandlung%20der%20Adipositas%20im%20Kindes-%20und%20Jugendalter%20m%5Cu00f6glich%20und%5C%2Foder%20sinnvoll%20ist%2C%20wird%20immer%20noch%20kontrovers%20diskutiert%20und%20muss%20derzeit%20nach%20Ansicht%20der%20Autoren%20noch%20unbeantwortet%20bleiben.%20Erst%20seit%20wenigen%20Jahren%20werden%20%5Cu00fcberhaupt%20randomisierte%20klinische%20Studien%20zum%20Thema%20%5Cu201eTherapie%20der%20Adipositas%20im%20Kindes-%20und%20Jugendalter%5Cu201c%20durchgef%5Cu00fchrt.%20Verschreibungszahlen%20f%5Cu00fcr%20Anti-Adipositas-Arzneimittel%20steigen%20insbesondere%20in%20England%20stark%20an.%20Nach%20Ansicht%20mancher%20Autoren%20sind%20zumindest%20zwei%20der%20zur%20Verf%5Cu00fcgung%20stehenden%20Therapeutika%20im%20Kontext%20mit%20einem%20Programm%20zur%20Lebensstil%5Cu00e4nderung%20wirksam.%20Aus%20medizinischer%20und%20gesundheits%5Cu00f6konomischer%20Sicht%20w%5Cu00e4re%20eine%20Gewichtsreduktion%20zur%20Verminderung%20des%20kardiovaskul%5Cu00e4ren%20Risikos%20und%20anderer%20Komorbidit%5Cu00e4ten%20und%20dadurch%20entstehender%20Kosten%20von%20gro%5Cu00dfer%20Bedeutung.%20Individuell%20sind%20dagegen%20Lebensqualit%5Cu00e4t%20%28die%20wiederum%20durch%20Komorbidit%5Cu00e4t%20beeinflusst%20werden%20k%5Cu00f6nnte%29%20und%20soziale%20Teilhabe%20wichtiger.%20Dies%20gilt%20insbesondere%20f%5Cu00fcr%20Kinder%20und%20Jugendliche%2C%20die%20die%20Langzeitfolgen%20ihrer%20Adipositas%20meist%20noch%20gar%20nicht%20absch%5Cu00e4tzen%20k%5Cu00f6nnen.%20Neben%20Behandlungsstrategien%20f%5Cu00fcr%20die%5C%2Fden%20einzelne%28n%29%20PatientIn%20auf%20individueller%20Ebene%20sind%20unserer%20Ansicht%20nach%20Interventionen%20und%20Pr%5Cu00e4ventionsma%5Cu00dfnahmen%20in%20der%20Gesellschaft%20beziehungsweise%20auf%20Populationsebene%20von%20allergr%5Cu00f6%5Cu00dfter%20Wichtigkeit.%22%2C%22date%22%3A%22May%202011%22%2C%22language%22%3A%22de%22%2C%22DOI%22%3A%2210.1007%5C%2Fs00103-011-1265-6%22%2C%22ISSN%22%3A%221436-9990%2C%201437-1588%22%2C%22url%22%3A%22http%3A%5C%2F%5C%2Flink.springer.com%5C%2F10.1007%5C%2Fs00103-011-1265-6%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-07T07%3A01%3A41Z%22%7D%7D%5D%7D
Wagner, Friederike, Robert Zeidler, Uta Ceglarek, Wieland Kiess, Jürgen Kratzsch, Alexander Gaudl, Ronald Biemann, and Mandy Vogel. “Obesity Is Associated with Increased 11-Oxyandrogen Serum Concentrations during Puberty.” Hormone Research in Paediatrics, July 22, 2024. https://doi.org/10.1159/000540433.
Fechner, Anna, Anja Willenberg, Niels Ziegelasch, Andreas Merkenschlager, Wieland Kiess, and Mandy Vogel. “Creatine Kinase Serum Levels in Children Revisited: New Reference Intervals from a Large Cohort of Healthy Children and Adolescents.” Clinica Chimica Acta 560 (June 15, 2024): 119726. https://doi.org/10.1016/j.cca.2024.119726.
Barzen, Charlotte, Mandy Vogel, Wieland Kiess, and Tanja Poulain. “Associations between Gestational Weight Gain and Weight Development of the Offspring: Differences Depending on Maternal Pre-Pregnancy BMI.” Archives of Gynecology and Obstetrics, April 13, 2024. https://doi.org/10.1007/s00404-024-07487-1.
Krause, Lea, Tanja Poulain, Wieland Kiess, and Mandy Vogel. “Body Image and Behavioural and Emotional Difficulties in German Children and Adolescents.” BMC Pediatrics 23, no. 1 (November 23, 2023): 594. https://doi.org/10.1186/s12887-023-04405-3.
Bier, Elisabeth, Mandy Vogel, Nico Grafe, Anne Jurkutat, Juliane Ludwig, Oleg Wagner, Christof Meigen, Wieland Kiess, and Tanja Poulain. “Children’s Satisfaction with a Comprehensive Study Program-Results from the LIFE Child Cohort Study.” Paediatric and Perinatal Epidemiology 37, no. 8 (November 2023): 704–9. https://doi.org/10.1111/ppe.13007.
Stein, Robert, Eric Göpel, Daniel Weghuber, Maximiliane Chiara Hammel, Mandy Vogel, Wieland Kiess, and Antje Körner. “Are There Relevant Thresholds of Insulin-Independent Indices across the Lifespan to Predict Alterations in Glycemic Control?—Authors’ Reply.” The Lancet Regional Health – Europe 33 (October 1, 2023): 100734. https://doi.org/10.1016/j.lanepe.2023.100734.
Hammel, Maximiliane Chiara, Robert Stein, Jürgen Kratzsch, Mandy Vogel, Alexander J. Eckert, Rima Destya Triatin, Marco Colombo, et al. “Fasting Indices of Glucose-Insulin-Metabolism across Life Span and Prediction of Glycemic Deterioration in Children with Obesity from New Diagnostic Cut-Offs.” The Lancet Regional Health. Europe 30 (July 2023): 100652. https://doi.org/10.1016/j.lanepe.2023.100652.
Förster, Lucas-Johann, Mandy Vogel, Robert Stein, Anja Hilbert, Julius Lars Breinker, Marleen Böttcher, Wieland Kiess, and Tanja Poulain. “Mental Health in Children and Adolescents with Overweight or Obesity.” BMC Public Health 23, no. 1 (January 19, 2023): 135. https://doi.org/10.1186/s12889-023-15032-z.
Stein, Robert, Florian Koutny, Johannes Riedel, Natascha Dörr, Klara Meyer, Marco Colombo, Mandy Vogel, et al. “Single Point Insulin Sensitivity Estimator (SPISE) as a Prognostic Marker for Emerging Dysglycemia in Children with Overweight or Obesity.” Metabolites 13, no. 1 (January 2023): 100. https://doi.org/10.3390/metabo13010100.
Kiess, Wieland, Anna S. Kirstein, Robert Stein, and Mandy Vogel. “Obesity After the Covid-19 Pandemic and Beyond.” Journal of Pediatric Endocrinology and Metabolism 35, no. 2 (February 2022): 135–38. https://doi.org/10.1515/jpem-2022-2135.
Vogel, Mandy, Mandy Geserick, Ruth Gausche, Christoph Beger, Tanja Poulain, Christof Meigen, Antje Körner, Eberhard Keller, Wieland Kiess, and Roland Pfäffle. “Age- and Weight Group-Specific Weight Gain Patterns in Children and Adolescents During the 15 Years Before and During the Covid-19 Pandemic.” International Journal of Obesity (2005) 46, no. 1 (January 2022): 144–52. https://doi.org/10.1038/s41366-021-00968-2.
Bohn, Claudia, Mandy Vogel, Tanja Poulain, Andreas Hiemisch, Wieland Kiess, and Antje Körner. “Having Siblings Promotes a More Healthy Weight Status-Whereas Only Children Are at Greater Risk for Higher BMI in Later Childhood.” PloS One 17, no. 7 (2022): e0271676. https://doi.org/10.1371/journal.pone.0271676.
Vogel, Mandy, Mandy Geserick, Ruth Gausche, Christoph Beger, Tanja Poulain, Christof Meigen, Antje Körner, et al. “Gewichtszunahme Bei Kindern Und Jugendlichen Während Der Covid-19-Pandemie.” Kinder- Und Jugendmedizin 22, no. 2 (2022): 112–17. https://doi.org/10.1055/a-1732-1623.
Eichler, Janina, Ricarda Schmidt, Tanja Poulain, Andreas Hiemisch, Wieland Kiess, and Anja Hilbert. “Maternal Depressive Symptoms and Stress During Pregnancy as Predictors of Gestational Age at Birth and Standardized Body Mass Index from Birth up to 2 Years of Age.” BMC Pregnancy and Childbirth 21, no. 1 (September 2021): 635. https://doi.org/10.1186/s12884-021-04111-x.
Kiess, Wieland, and Gabriele Haeusler. “Endocrine-Disrupting Chemicals.” Best Practice & Research. Clinical Endocrinology & Metabolism 35, no. 5 (September 2021): 101566. https://doi.org/10.1016/j.beem.2021.101566.
Kempf, Elena, Mandy Vogel, Tim Vogel, Jürgen Kratzsch, Kathrin Landgraf, Andreas Kühnapfel, Ruth Gausche, et al. “Dynamic Alterations in Linear Growth and Endocrine Parameters in Children with Obesity and Height Reference Values.” EClinicalMedicine 37 (June 2021): 100977. https://doi.org/10.1016/j.eclinm.2021.100977.
Bohn, Claudia, Mandy Vogel, Tanja Poulain, Ulrike Spielau, Cornelia Hilbert, Wieland Kiess, and Antje Körner. “Birth Weight Increases with Birth Order Despite Decreasing Maternal Pregnancy Weight Gain.” Acta Paediatrica 110, no. 4 (2021): 1218–24. https://doi.org/10.1111/apa.15598.
Vogelezang, Suzanne, Jonathan P. Bradfield, Tarunveer S. Ahluwalia, John A. Curtin, Timo A. Lakka, Niels Grarup, Markus Scholz, et al. “Novel Loci for Childhood Body Mass Index and Shared Heritability with Adult Cardiometabolic Traits.” PLOS Genetics 16, no. 10 (October 2020): e1008718. https://doi.org/10.1371/journal.pgen.1008718.
Poulain, Tanja, Carolin Sobek, Juliane Ludwig, Ulrike Igel, Gesine Grande, Verena Ott, Wieland Kiess, Antje Körner, and Mandy Vogel. “Associations of Green Spaces and Streets in the Living Environment with Outdoor Activity, Media Use, Overweight/Obesity and Emotional Wellbeing in Children and Adolescents.” International Journal of Environmental Research and Public Health 17, no. 17 (August 2020): 6321. https://doi.org/10.3390/ijerph17176321.
Flemming, Gunter, Sarah Bussler, Antje Körner, and Wieland Kiess. “Definition and Early Diagnosis of Metabolic Syndrome in Children.” Journal of Pediatric Endocrinology & Metabolism: JPEM 33, no. 7 (July 28, 2020): 821–33. https://doi.org/10.1515/jpem-2019-0552.
Kiess, Alexandra, Antje Körner, Ingo Dähnert, Mandy Vogel, Franziska Markel, Roman A. Gebauer, Wieland Kiess, and Christian Paech. “Does Obesity Have an Effect on the Ecg in Children?” Journal of Pediatric Endocrinology & Metabolism: JPEM 33, no. 5 (May 2020): 585–89. https://doi.org/10.1515/jpem-2019-0539.
Geserick, M., M. Vogel, F. Eckelt, M. Schlingmann, A. Hiemisch, R. Baber, J. Thiery, A. Körner, W. Kiess, and J. Kratzsch. “Children and Adolescents with Obesity Have Reduced Serum Bone Turnover Markers and 25-Hydroxyvitamin D but Increased Parathyroid Hormone Concentrations – Results Derived from New Pediatric Reference Ranges.” Bone 132 (2020): 115124. https://doi.org/10.1016/j.bone.2019.115124.
Schmidt, Ricarda, Andreas Hiemisch, Wieland Kiess, and Anja Hilbert. “Interaction Effects of Child Weight Status and Parental Feeding Practices on Children’s Eating Disorder Symptomatology.” Nutrients 11, no. 10 (October 2019): 2433. https://doi.org/10.3390/nu11102433.
Gramss, Manuela, Tobias Lipek, Mandy Vogel, Johannes Remmler, Andreas Hiemisch, Anne Jurkutat, Jon Genuneit, Antje Körner, and Wieland Kiess. “Overweight Proxies Are Associated with Atopic Asthma: A Matched Case-Control Study.” Hormone Research in Paediatrics 91, no. 6 (August 2019): 380–90. https://doi.org/10.1159/000501685.
Buzek, Theresa, Tanja Poulain, Mandy Vogel, Christoph Engel, Sarah Bussler, Antje Körner, Andreas Hiemisch, and Wieland Kiess. “Relations Between Sleep Duration with Overweight and Academic Stress—Just a Matter of the Socioeconomic Status?” Sleep Health 5, no. 2 (April 1, 2019): 208–15. https://doi.org/10.1016/j.sleh.2018.12.004.
Schmidt, Jana, Pia Strecker, Markus Kreuz, Markus Löffler, Wieland Kiess, Christian Hirsch, Joachim Thiery, et al. “Stress-Related Hormones in Association with Periodontal Condition in Adolescents-Results of the Epidemiologic Life Child Study.” Clinical Oral Investigations 23, no. 4 (April 2019): 1793–1802. https://doi.org/10.1007/s00784-018-2599-3.
Körner, Antje, Wieland Kiess, and Mandy Vogel. “Persistence of Obesity from Early Childhood Onward.” The New England Journal of Medicine 380, no. 2 (January 2019): 194–95. https://doi.org/10.1056/NEJMc1814961.
Geserick, Mandy, Mandy Vogel, Ruth Gausche, Tobias Lipek, Ulrike Spielau, Eberhard Keller, Roland Pfäffle, Wieland Kiess, and Antje Körner. “Acceleration of BMI in Early Childhood and Risk of Sustained Obesity.” The New England Journal of Medicine 379, no. 14 (October 2018): 1303–12. https://doi.org/10.1056/NEJMoa1803527.
Loeffler-Wirth, Henry, Mandy Vogel, Toralf Kirsten, Fabian Glock, Tanja Poulain, Antje Körner, Markus Loeffler, Wieland Kiess, and Hans Binder. “Longitudinal Anthropometry of Children and Adolescents Using 3d-Body Scanning.” PloS One 13, no. 9 (September 2018): e0203628. https://doi.org/10.1371/journal.pone.0203628.
Rocha, Edrienny Patrícia Alves Accioly, Mandy Vogel, Juraj Stanik, Diana Pietzner, Anja Willenberg, Antje Körner, and Wieland Kiess. “Serum Uric Acid Levels as an Indicator for Metabolically Unhealthy Obesity in Children and Adolescents.” Hormone Research in Paediatrics 90, no. 1 (September 2018): 19–27. https://doi.org/10.1159/000490113.
Paech, C., A. Liebold, R. A. Gebauer, F. Wagner, M. Vogel, T. Kirsten, M. Schauff, et al. “Relative Qt Interval Prolongation and Electrical Inhomogeneity of Cardiac Repolarization in Childhood Obesity.” Progress in Pediatric Cardiology 47, no. Supplement C (December 1, 2017): 64–67. https://doi.org/10.1016/j.ppedcard.2017.08.001.
Kess, Annette, Ulrike Spielau, Christoph Beger, Ruth Gausche, Mandy Vogel, Tobias Lipek, Antje Körner, Roland Pfäffle, and Wieland Kiess. “Further Stabilization and Even Decrease in the Prevalence Rates of Overweight and Obesity in German Children and Adolescents from 2005 to 2015: A Cross-Sectional and Trend Analysis.” Public Health Nutrition 20, no. 17 (December 2017): 3075–83. https://doi.org/10.1017/S1368980017002257.
Loeffler-Wirth, Henry, Mandy Vogel, Toralf Kirsten, Fabian Glock, Tanja Poulain, Antje Körner, Markus Loeffler, Wieland Kiess, and Hans Binder. “Body Typing of Children and Adolescents Using 3d-Body Scanning.” PloS One 12, no. 10 (October 2017): e0186881. https://doi.org/10.1371/journal.pone.0186881.
Junge, Jennifer, Christoph Engel, Mandy Vogel, Stephanie Naumann, Markus Löffler, Joachim Thiery, Jürgen Kratzsch, Wieland Kiess, and Antje Körner. “Neck Circumference Is Similarly Predicting for Impairment of Glucose Tolerance as Classic Anthropometric Parameters Among Healthy and Obese Children and Adolescents.” Journal of Pediatric Endocrinology and Metabolism 30, no. 6 (May 2017): 643–50. https://doi.org/10.1515/jpem-2017-0079.
Bussler, Sarah, Melanie Penke, Gunter Flemming, Yasir S. Elhassan, Jürgen Kratzsch, Elena Sergeyev, Tobias Lipek, et al. “Novel Insights in the Metabolic Syndrome in Childhood and Adolescence.” Hormone Research in Paediatrics 88, no. 3–4 (2017): 181–93. https://doi.org/10.1159/000479510.
Schreier, Moritz, Julian Tristan Schwartze, Kathrin Landgraf, Kathrin Scheuermann, Sandra Erbs, Gunda Herberth, J. Andrew Pospisilik, Jürgen Kratzsch, Wieland Kiess, and Antje Körner. “Osteopontin Is Bmi-Independently Related to Early Endothelial Dysfunction in Children.” Journal of Pediatric Endocrinology and Metabolism 101, no. 11 (November 2016): 4161–69. https://doi.org/10.1210/jc.2016-2238.
Landgraf, Kathrin, Markus Scholz, Peter Kovacs, Wieland Kiess, and Antje Körner. “FTO Obesity Risk Variants Are Linked to Adipocyte IRX3 Expression and BMI of Children – Relevance of FTO Variants to Defend Body Weight in Lean Children?” PLOS ONE 11, no. 8 (August 2016): e0161739. https://doi.org/10.1371/journal.pone.0161739.
Sonnengrün, Lilli, Celestina Schober, Mandy Vogel, Andreas Hiemisch, Mirko Döhnert, Anja Hilbert, and Wieland Kiess. “Feeding, Eating and Behavioral Disturbances in Prader-Willi Syndrome and Non-Syndromal Obesity.” Journal of Pediatric Endocrinology and Metabolism 29, no. 8 (June 2016): 923–32. https://doi.org/10.1515/jpem-2016-0085.
Gramß, Manuela, Andreas Hiemisch, and Wieland Kiess. “Stellt Übergewicht ein Risiko für die Entwicklung von Asthma bronchiale im Kindes- und Jugendalter dar?” Adipositas – Ursachen, Folgeerkrankungen, Therapie 10, no. 2 (2016): 88–92. https://doi.org/10.1055/s-0037-1617702.
Penke, Melanie, Per S. Larsen, Susanne Schuster, Morten Dall, Benjamin A. H. Jensen, Theresa Gorski, Andrej Meusel, et al. “Hepatic Nad Salvage Pathway Is Enhanced in Mice on a High-Fat Diet.” Molecular and Cellular Endocrinology 412 (September 5, 2015): 65–72. https://doi.org/10.1016/j.mce.2015.05.028.
Kiess, Wieland, Elena Sergejev, Antje Körner, and Johannes Hebebrand. “Ist eine Therapie der Adipositas im Kindes- und Jugendalter überhaupt möglich?” Bundesgesundheitsblatt – Gesundheitsforschung – Gesundheitsschutz 54, no. 5 (May 2011): 527–32. https://doi.org/10.1007/s00103-011-1265-6.
2390247
T52N9QLZ
eye
1
chicago-fullnote-bibliography
50
date
desc
1
1
6748
https://home.uni-leipzig.de/lifechild/wp-content/plugins/zotpress/
%7B%22status%22%3A%22success%22%2C%22updateneeded%22%3Afalse%2C%22instance%22%3Afalse%2C%22meta%22%3A%7B%22request_last%22%3A0%2C%22request_next%22%3A0%2C%22used_cache%22%3Atrue%7D%2C%22data%22%3A%5B%7B%22key%22%3A%22W2VX5D8K%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Rauscher%20et%20al.%22%2C%22parsedDate%22%3A%222023-07%22%2C%22numChildren%22%3A2%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3ERauscher%2C%20Franziska%20G.%2C%20Andreas%20Hiemisch%2C%20Wieland%20Kiess%2C%20and%20Ralf%20Blendowske.%20%26%23x201C%3BMonochromatic%20Ocular%20High-Order%20Aberrations%20in%20Children%20and%20Adolescents.%26%23x201D%3B%20%3Ci%3EOphthalmic%20%26amp%3B%20Physiological%20Optics%3A%20The%20Journal%20of%20the%20British%20College%20of%20Ophthalmic%20Opticians%20%28Optometrists%29%3C%5C%2Fi%3E%2043%2C%20no.%204%20%28July%202023%29%3A%20842%26%23×2013%3B59.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fopo.13151%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fopo.13151%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Monochromatic%20ocular%20high-order%20aberrations%20in%20children%20and%20adolescents%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Franziska%20G.%22%2C%22lastName%22%3A%22Rauscher%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andreas%22%2C%22lastName%22%3A%22Hiemisch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ralf%22%2C%22lastName%22%3A%22Blendowske%22%7D%5D%2C%22abstractNote%22%3A%22PURPOSE%3A%20To%20investigate%20the%20prevalence%20and%20repeatability%20of%20high-order%20aberrations%20%28HOAs%29%20from%20non-cyclopleged%20eyes%20in%201515%20children%20and%20adolescents%202.5-18%5Cu2009years%20of%20age.%5CnMETHODS%3A%20The%20Leipzig%20Research%20Centre%20for%20Civilization%20Diseases%20%28LIFE%29-Child%20study%20is%20a%20population-based%2C%20prospective%2C%20observational%20single-centre%20study%20that%20investigates%20the%20development%20of%20children%20and%20adolescents%20in%20Germany.%20Wavefront%20measurements%20were%20repeated%20three%20times%20in%20each%20eye%20of%201515%20healthy%20subjects.%20Results%20were%20described%20by%2036%20Zernike%20coefficients%20for%20a%205%5Cu2009mm%20reference%20pupil%20diameter.%20Short-term%20repeatability%20is%20given%20for%20each%20coefficient.%20The%20impact%20on%20vision%20is%20described%20by%20the%20root%20mean%20squared%20%28RMS%29%20value%20of%20the%20HOA%20Zernike%20coefficients.%5CnRESULTS%3A%20High-order%20aberrations%20were%20dominated%20by%20five%20contributions.%20For%201004%20right%20eyes%3A%20spherical%20aberration%20%28c12%20%5Cu2009%3D%5Cu20090.06%5Cu2009%5Cu00b1%5Cu20090.07%5Cu2009%5Cu03bcm%29%2C%20coma%20%28c7%20%5Cu2009%3D%5Cu20090.03%5Cu2009%5Cu00b1%5Cu20090.09%5Cu2009%5Cu03bcm%2C%20c8%20%5Cu2009%3D%5Cu20090.03%5Cu2009%5Cu00b1%5Cu20090.06%5Cu2009%5Cu03bcm%29%20and%20trefoil%20%28c6%20%5Cu2009%3D%5Cu2009-0.01%5Cu2009%5Cu00b1%5Cu20090.07%5Cu2009%5Cu03bcm%2C%20c9%20%5Cu2009%3D%5Cu20090.008%5Cu2009%5Cu00b1%5Cu20090.06%5Cu2009%5Cu03bcm%29.%20The%20RMS%20value%20was%200.18%5Cu2009%5Cu00b1%5Cu20090.06%5Cu2009%5Cu03bcm.%20Modes%20higher%20than%20fourth%20order%20do%20not%20contribute%20clinically%20to%20the%20aberrations.%20HOAs%20show%20no%20clinically%20significant%20dependency%20with%20age.%20Instead%2C%20HOA%20values%20agree%20well%20with%20previous%20results%20on%20aberrations%20in%20adult%20eyes.%20Spherical%20aberration%20was%20highly%20correlated%20between%20the%20two%20eyes.%20Repeatability%20was%20worst%20for%20coma%2C%200.033%5Cu2009%5Cu03bcm%2C%20due%20to%20variability%20in%20the%20alignment%20of%20the%20pupil%20centre.%20The%20left%20eye%20showed%2C%20on%20average%2C%20a%200.08%5Cu2009mm%20larger%20pupil%20diameter%20than%20the%20right%20eye%20%28p%5Cu2009%3C%5Cu20090.02%29.%5CnCONCLUSIONS%3A%20Across%20the%20age%20span%20from%202.5%20to%2018%5Cu2009years%2C%20we%20see%20the%20same%20distribution%20of%20HOA%20as%20for%20adults.%20We%20established%20that%20only%20five%20Zernike%20coefficients%2C%20spherical%20aberration%2C%20coma%20and%20trefoil%20were%20of%20clinical%20significance%20in%20healthy%20eyes.%20A%20high%20correlation%20between%20the%20two%20eyes%20for%20spherical%20aberration%20suggests%20a%20common%20blueprint%20for%20each%20eye%20in%20any%20one%20subject.%22%2C%22date%22%3A%222023-07%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1111%5C%2Fopo.13151%22%2C%22ISSN%22%3A%221475-1313%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222024-08-27T11%3A44%3A47Z%22%7D%7D%2C%7B%22key%22%3A%22KXRLYRQ4%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22S%5Cu00f6hnel%20et%20al.%22%2C%22parsedDate%22%3A%222023-03-17%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3ES%26%23xF6%3Bhnel%2C%20Tanja%2C%20Christof%20Meigen%2C%20Andreas%20Hiemisch%2C%20Siegfried%20Wahl%2C%20Focke%20Ziemssen%2C%20Carolin%20Truckenbrod%2C%20Katharina%20H%26%23xFC%3Bbner%2C%20and%20Wieland%20Kiess.%20%26%23x201C%3BNormative%20Data%20for%20Macular%20and%20Retinal%20Nerve%20Fibre%20Layer%20Thickness%20in%20Healthy%20German%20Children%20and%20Adolescents%20Using%20Optical%20Coherence%20Tomography.%26%23x201D%3B%20%3Ci%3EOphthalmic%20and%20Physiological%20Optics%3C%5C%2Fi%3E%2C%20March%2017%2C%202023%2C%20opo.13123.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fopo.13123%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fopo.13123%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Normative%20data%20for%20macular%20and%20retinal%20nerve%20fibre%20layer%20thickness%20in%20healthy%20German%20children%20and%20adolescents%20using%20optical%20coherence%20tomography%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22S%5Cu00f6hnel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christof%22%2C%22lastName%22%3A%22Meigen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andreas%22%2C%22lastName%22%3A%22Hiemisch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Siegfried%22%2C%22lastName%22%3A%22Wahl%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Focke%22%2C%22lastName%22%3A%22Ziemssen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Carolin%22%2C%22lastName%22%3A%22Truckenbrod%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Katharina%22%2C%22lastName%22%3A%22H%5Cu00fcbner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%5D%2C%22abstractNote%22%3A%22Purpose%3A%20To%20establish%20normative%20data%20for%20macular%20thickness%2C%20macular%20volume%20and%20peripapillary%20retinal%20nerve%20fibre%20layer%20%28RNFL%29%20thickness%20using%20Spectralis%5Cu00ae%20spectral-%5Cu00ad%20domain%20optical%20coherence%20tomography%20%28SD-%5Cu00adOCT%29%20in%20healthy%20German%20children%20and%20adolescents%20and%20investigate%20influencing%20factors.%5CnMethods%3A%20The%20cross-%5Cu00adsectional%20study%20included%20the%20right%20eye%20of%20695%20children%20with%20at%20least%20one%20complete%20retinal%20OCT%20scan.%20As%20part%20of%20the%20LIFE%20Child%20study%2C%20the%20children%20underwent%20an%20ophthalmological%20examination%20including%20axial%20length%20%28AL%29%2C%20spherical%20equivalent%20%28SE%29%20and%20OCT%20measurements.%20Various%20questionnaires%20were%20answered%20by%20the%20children%20or%20their%20parents%20to%20identify%20media%20use%20or%20outdoor%20time.%20Multiple%20linear%20regression%20models%20were%20used%20to%20investigate%20the%20potential%20influencing%20factors.%5CnResults%3A%20A%20total%20of%20342%20boys%20and%20353%20girls%20with%20an%20average%20age%20%28SD%29%20of%2012.91%20%283.29%29%20years%20participated.%20The%20mean%20AL%20%28SD%29%20was%2023.20%20%280.86%29%20mm.%20The%20mean%20macular%20thickness%20%28SD%29%20was%20320.53%20%2812.29%29%20%5Cu03bcm%20and%20the%20mean%20RNFL%20thickness%20%28SD%29%20was%20102.88%20%288.79%29%20%5Cu03bcm.%20Statistical%20analysis%20revealed%20a%20significant%20correlation%20between%20average%20macular%20thickness%20and%20age%20%28p%5Cu2009%3C%5Cu20090.001%2C%20%5Cu03b2%20%3D%200.77%29%20as%20well%20as%20AL%20%28p%5Cu2009%3C%5Cu20090.001%2C%20%5Cu03b2%20%3D%20%5Cu22124.06%29.%20In%20addition%2C%20boys%20had%20thicker%20maculae%20%28p%5Cu2009%3C%5Cu20090.001%2C%20%5Cu03b2%20%3D%205.36%29.%20The%20RNFL%20thickness%20showed%20no%20significant%20correlation%20with%20children%27s%20age%20%28p%5Cu2009%3E%5Cu20090.05%29%2C%20but%20with%20AL%20%28p%20%3D%200.002%2C%20%5Cu03b2%20%3D%20%5Cu22122.15%29%2C%20birth%20weight%20%28p%20%3D%200.02%2C%20%5Cu03b2%20%3D%200.003%29%20and%20a%20gender-%5Cu00adspecific%20effect%20of%20the%20body%20mass%20index%20standard%20deviation%20score%20for%20male%20participants%20%28p%20%3D%200.02%2C%20%5Cu03b2%20%3D%201.93%29.%5CnConclusion%3A%20This%20study%20provides%20normative%20data%20and%20correlations%20between%20macular%20and%20RNFL%20thickness%20in%20healthy%20German%20children.%20Especially%20age%2C%20gender%20and%20AL%20must%20be%20taken%20into%20account%20when%20evaluating%20quantitative%20OCT%20measurements%20to%20classify%20them%20as%20normal.%22%2C%22date%22%3A%222023-03-17%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1111%5C%2Fopo.13123%22%2C%22ISSN%22%3A%220275-5408%2C%201475-1313%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fonlinelibrary.wiley.com%5C%2Fdoi%5C%2F10.1111%5C%2Fopo.13123%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222024-08-27T13%3A11%3A16Z%22%7D%7D%2C%7B%22key%22%3A%22J6B8PXY7%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Philipp%20et%20al.%22%2C%22parsedDate%22%3A%222022-11-10%22%2C%22numChildren%22%3A2%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EPhilipp%2C%20Dariusch%2C%20Mandy%20Vogel%2C%20Manuela%20Brandt%2C%20Franziska%20G.%20Rauscher%2C%20Andreas%20Hiemisch%2C%20Siegfried%20Wahl%2C%20Wieland%20Kiess%2C%20and%20Tanja%20Poulain.%20%26%23x201C%3BThe%20Relationship%20between%20Myopia%20and%20near%20Work%2C%20Time%20Outdoors%20and%20Socioeconomic%20Status%20in%20Children%20and%20Adolescents.%26%23x201D%3B%20%3Ci%3EBMC%20Public%20Health%3C%5C%2Fi%3E%2022%2C%20no.%201%20%28November%2010%2C%202022%29%3A%202058.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs12889-022-14377-1%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs12889-022-14377-1%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22The%20relationship%20between%20myopia%20and%20near%20work%2C%20time%20outdoors%20and%20socioeconomic%20status%20in%20children%20and%20adolescents%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Dariusch%22%2C%22lastName%22%3A%22Philipp%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Manuela%22%2C%22lastName%22%3A%22Brandt%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Franziska%20G.%22%2C%22lastName%22%3A%22Rauscher%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andreas%22%2C%22lastName%22%3A%22Hiemisch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Siegfried%22%2C%22lastName%22%3A%22Wahl%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%5D%2C%22abstractNote%22%3A%22BACKGROUND%3A%20To%20investigate%20environmental%20and%20social%20risk%20factors%20for%20myopia%20in%20children%20and%20adolescents%20in%20Germany.%5CnMETHODS%3A%201437%20children%20aged%20between%203%20and%2018%20inclusive%20were%20examined%20as%20part%20of%20the%20LIFE%20Child%20study%20based%20in%20Leipzig%2C%20Germany.%20Information%20about%20leisure%20time%20activities%20and%20social%20status%20was%20ascertained%20by%20parents%20and%20children%20in%20a%20questionnaire.%20Refractive%20status%20was%20attained%20by%20measuring%20noncycloplegic%20autorefraction.%20Myopia%20was%20defined%20as%20spherical%20equivalent%20%28SE%29%5Cu2009%5Cu2264%5Cu2009-%5Cu20090.75%20D.%20Risk%20factors%20were%20identified%20using%20multiple%20logistic%20regression%20analysis.%5CnRESULTS%3A%20In%20multiple%20logistic%20regression%20analysis%2C%20myopia%20was%20significantly%20associated%20with%20less%20frequent%20outdoor%20activity%20%28%5C%22once%20a%20week%5C%22%20vs.%20%5C%22twice%20a%20week%20or%20more%5C%22%3A%20odds%20ratio%20%28OR%29%204.35%2C%2095%25%20confidence%20interval%20%28CI%29%201.89-9.98%2C%20p%26lt%3B0.01%29%20and%20longer%20near%20work%20sessions%20%281-2%5Cu00a0h%20vs.%20%26lt%3B%201%5Cu00a0h%3A%20OR%201.83%2C%20CI%201.10-3.04%2C%20p%3D0.02%3B%20%26gt%3B%203%5Cu00a0h%20vs.%20%26lt%3B%201%5Cu00a0h%3A%20OR%203.71%2C%20CI%201.43-9.61%2C%20p%26lt%3B0.01%29%20after%20adjustment%20for%20age%2C%20sex%20and%20socioeconomic%20status%20%28SES%29.%20Duration%20of%20outdoor%20activity%2C%20near%20work%20frequency%20and%20SES%20showed%20no%20significant%20association%20with%20myopia%20%28p%5Cu2009%26gt%3B%5Cu20090.05%29.%20Children%20with%20a%20lower%20SES%20were%20involved%20in%20longer%20periods%20of%20outdoor%20and%20near%20work%20activities%20but%20on%20fewer%20occasions%20over%20the%20course%20of%20the%20week%2C%20although%20this%20connection%20was%20not%20significant.%5CnCONCLUSION%3A%20Myopia%20is%20associated%20with%20environmental%20factors.%20The%20present%20findings%20suggest%20that%20daily%20exposure%20to%20sunlight%20and%20a%20restriction%20of%20long-duration%20near%20work%20activities%20might%20protect%20against%20pathological%20eye%20growth.%20Prevention%20strategies%20should%20be%20implemented%20for%20children%20at%20all%20ages.%22%2C%22date%22%3A%222022-11-10%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1186%5C%2Fs12889-022-14377-1%22%2C%22ISSN%22%3A%221471-2458%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222024-08-27T13%3A13%3A26Z%22%7D%7D%2C%7B%22key%22%3A%22FDXE5QU4%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Rauscher%20et%20al.%22%2C%22parsedDate%22%3A%222021-05%22%2C%22numChildren%22%3A2%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3ERauscher%2C%20Franziska%20G.%2C%20Mike%20Francke%2C%20Andreas%20Hiemisch%2C%20Wieland%20Kiess%2C%20and%20Ralph%20Michael.%20%26%23x201C%3BOcular%20Biometry%20in%20Children%20and%20Adolescents%20from%204%20to%2017%20Years%3A%20A%20Cross-Sectional%20Study%20in%20Central%20Germany.%26%23x201D%3B%20%3Ci%3EOphthalmic%20and%20Physiological%20Optics%3C%5C%2Fi%3E%2041%2C%20no.%203%20%28May%202021%29%3A%20496%26%23×2013%3B511.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fopo.12814%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fopo.12814%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Ocular%20Biometry%20in%20Children%20and%20Adolescents%20from%204%20to%2017%20Years%3A%20A%20Cross-Sectional%20Study%20in%20Central%20Germany%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Franziska%20G.%22%2C%22lastName%22%3A%22Rauscher%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mike%22%2C%22lastName%22%3A%22Francke%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andreas%22%2C%22lastName%22%3A%22Hiemisch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ralph%22%2C%22lastName%22%3A%22Michael%22%7D%5D%2C%22abstractNote%22%3A%22Purpose%20To%20evaluate%20ocular%20biometry%20in%20a%20large%20paediatric%20population%20as%20a%20function%20of%20age%20and%20sex%20in%20children%20of%20European%20descent.%20Methods%20Children%20were%20examined%20as%20part%20of%20the%20LIFE%20Child%20Study%20%28Leipzig%20Research%20Centre%20for%20Civilization%20Disease%29%2C%20a%20population-based%20study%20in%20Leipzig%2C%20Germany.%20Altogether%2C%201907%20children%2C%20aged%20from%204%20to%2017%20years%2C%20were%20examined%20with%20the%20Lenstar%20LS%20900.%20Data%20from%20the%20right%20eye%20was%20analysed%20for%20axial%20length%2C%20central%20corneal%20thickness%2C%20flat%20and%20steep%20corneal%20radii%2C%20aqueous%20depth%2C%20lens%20thickness%20and%20vitreous%20depth.%20Wavefront-based%20autorefraction%20was%20employed%20for%20analysis.%20Results%20Axial%20length%20increased%20in%20girls%20from%2021.6%20mm%20%284%20years%29%20up%20to%2023.4%20mm%20%2817%20years%29%3B%20this%20increase%20%280.174%20mm%20per%20year%29%20was%20statistically%20significant%20up%20to%20age%2014%20%2823.3%20mm%29.%20Axial%20length%20increased%20in%20boys%20from%2022.2%20mm%20%284%20years%29%20up%20to%2023.9%20mm%20%2817%20years%29%3B%20this%20increase%20%280.178%20mm%20per%20year%29%20was%20statistically%20significant%20up%20to%20age%2010%20%2823.3%20mm%29.%20No%20change%20was%20observed%20for%20central%20corneal%20thickness%20%28average%3A%20girls%20550%20%5Cu00b5m%3B%20boys%20554%20%5Cu00b5m%29.%20Corneal%20curvature%20in%20girls%20was%20somewhat%20flatter%20at%20age%204%20%287.70%20mm%29%20compared%20to%20age%2010%20%287.78%20mm%29%2C%20whereas%20it%20was%20constant%20in%20boys%20%287.89%20mm%29.%20Aqueous%20depth%20at%20age%204%20was%202.73%20mm%20for%20girls%20and%202.86%20mm%20for%20boys%2C%20with%20the%20same%20rate%20of%20increase%20per%20year%20%28girls%3A%200.046%20mm%3B%20boys%3A%200.047%20mm%29%20from%20age%204%20to%2010.%20At%20age%2017%2C%20aqueous%20depth%20was%203.06%20mm%20in%20girls%20and%203.20%20mm%20in%20boys.%20Lens%20thickness%20was%20reduced%20from%20age%204%20%283.75%20mm%29%20to%20age%2010%20%283.47%20mm%29%20in%20girls%20and%20from%20age%204%20%283.73%20mm%29%20to%20age%2010%20%283.44%20mm%29%20in%20boys%2C%20with%20the%20same%20rate%20of%20decrease%20per%20year%20of%200.046%20and%200.047%20mm%2C%20respectively.%20At%20age%2017%2C%20lens%20thickness%20was%203.52%20mm%20in%20girls%20and%203.50%20mm%20in%20boys.%20Vitreous%20depth%20at%20age%204%20was%2014.51%20mm%20for%20girls%20and%2015.08%20mm%20for%20boys%3B%20with%200.156%20mm%20%28girls%29%20or%200.140%20mm%20%28boys%29%20increase%20per%20year%20until%20age%2014%20%28girls%3A%2016.08%20mm%3B%20boys%3A%2016.48%20mm%29.%20At%20age%2017%2C%20vitreous%20depth%20was%2016.29%20mm%20in%20girls%20and%2016.62%20mm%20in%20boys.%20Conclusions%20Eye%20growth%20%28axial%20length%29%20in%20girls%20showed%20a%20lag%20of%20about%20four%20years%20compared%20to%20boys.%20Aqueous%20depth%20increase%20matches%20the%20lens%20thickness%20decrease%20from%20ages%204%20to%2010%20years%20in%20girls%20and%20boys.%20Lens%20thickness%20minimum%20is%20reached%20at%2011%20years%20in%20girls%20and%20at%2012%20years%20in%20boys.%20All%20dimensions%20of%20the%20optical%20ocular%20components%20are%20closely%20correlated%20with%20axial%20length.%20These%20data%20may%20serve%20as%20normative%20values%20for%20the%20assessment%20of%20eye%20growth%20in%20central%20European%20children%20and%20will%20provide%20a%20basis%20for%20monitoring%20refractive%20error%20development.%22%2C%22date%22%3A%222021-05%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1111%5C%2Fopo.12814%22%2C%22ISSN%22%3A%221475-1313%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fonlinelibrary.wiley.com%5C%2Fdoi%5C%2Fabs%5C%2F10.1111%5C%2Fopo.12814%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-27T08%3A48%3A40Z%22%7D%7D%2C%7B%22key%22%3A%22Q3I3H44N%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Truckenbrod%20et%20al.%22%2C%22parsedDate%22%3A%222021-05%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3ETruckenbrod%2C%20Carolin%2C%20Christof%20Meigen%2C%20Manuela%20Brandt%2C%20Mandy%20Vogel%2C%20Pablo%20Sanz%20Diez%2C%20Siegfried%20Wahl%2C%20Anne%20Jurkutat%2C%20and%20Wieland%20Kiess.%20%26%23x201C%3BLongitudinal%20Analysis%20of%20Axial%20Length%20Growth%20in%20a%20German%20Cohort%20of%20Healthy%20Children%20and%20Adolescents.%26%23x201D%3B%20%3Ci%3EOphthalmic%20%26amp%3B%20Physiological%20Optics%3A%20The%20Journal%20of%20the%20British%20College%20of%20Ophthalmic%20Opticians%20%28Optometrists%29%3C%5C%2Fi%3E%2041%2C%20no.%203%20%28May%202021%29%3A%20532%26%23×2013%3B40.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fopo.12817%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fopo.12817%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Longitudinal%20Analysis%20of%20Axial%20Length%20Growth%20in%20a%20German%20Cohort%20of%20Healthy%20Children%20and%20Adolescents%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Carolin%22%2C%22lastName%22%3A%22Truckenbrod%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christof%22%2C%22lastName%22%3A%22Meigen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Manuela%22%2C%22lastName%22%3A%22Brandt%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Pablo%22%2C%22lastName%22%3A%22Sanz%20Diez%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Siegfried%22%2C%22lastName%22%3A%22Wahl%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anne%22%2C%22lastName%22%3A%22Jurkutat%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%5D%2C%22abstractNote%22%3A%22PURPOSE%3A%20To%20generate%20continuous%20growth%20curves%20for%20axial%20length%20%28AL%29%20in%20German%20children.%20We%20hypothesise%20that%20percentile%20curves%20of%20AL%20can%20be%20used%20as%20a%20predictive%20measure%20of%20myopia.%5CnMETHODS%3A%20In%20this%20longitudinal%20and%20cross-sectional%20LIFE%20Child%20Study%2C%20children%27s%20non-cycloplegic%20refraction%20data%20was%20collected%20using%20the%20Zeiss%20i.Profiler%20plus%20while%20AL%20was%20measured%20using%20the%20Haag-Streit%20Lenstar.%20Reference%20growth%20curves%20were%20estimated%20as%20a%20continuous%20non-parametric%20function%20of%20age.%5CnRESULTS%3A%20Data%20from%204511%20visits%20of%201965%20participants%20%281021%20boys%20and%20944%20girls%29%20between%203%20and%2018%5Cu00a0years%20of%20age%20were%20analysed.%20For%20all%20ages%20and%20percentiles%2C%20the%20estimated%20AL%20was%20higher%20in%20boys%20than%20girls.%20AL%20differences%20between%20boys%20and%20girls%20were%20most%20pronounced%20in%20the%2098th%20percentile%20at%203%5Cu00a0years%20of%20age%2C%20being%200.93%5Cu00a0mm%20longer%20eyes%20in%20boys.%20This%20difference%20decreased%20to%200.21%5Cu00a0mm%20at%2018%5Cu00a0years%20of%20age.%20While%20the%20lower%20percentiles%20of%20AL%20reach%20their%20final%20value%20around%20age%2013%2C%20the%2050th%20percentile%20was%20still%20increasing%20by%200.05%5Cu00a0mm%20per%20year%20until%20the%20end%20of%20the%20observation%20period.%20While%2C%20in%20general%2C%20children%20with%20longer%20eyes%20are%20more%20likely%20to%20develop%20myopia%2C%20this%20relationship%20is%20weaker%20between%20the%20ages%20of%205%20and%208.%5CnCONCLUSION%3A%20The%20LIFE%20Child%20Study%20data%20provides%20European%20AL%20data.%20In%20both%20Germany%20and%20China%2C%20AL%20has%20comparable%20growth%20rates%20when%20the%20baseline%20ALs%20are%20compared%20as%20percentiles.%20Thus%2C%20percentile%20curves%20of%20AL%20can%20be%20used%20as%20a%20predictive%20measure%20for%20the%20likelihood%20of%20developing%20as%20well%20as%20the%20progression%20of%20myopia.%22%2C%22date%22%3A%222021-05%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1111%5C%2Fopo.12817%22%2C%22ISSN%22%3A%221475-1313%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Forgid.org%5C%2F10.1111%5C%2Fopo.12817%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-24T13%3A30%3A03Z%22%7D%7D%2C%7B%22key%22%3A%2248NV9UNG%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Rauscher%20et%20al.%22%2C%22parsedDate%22%3A%222021-03%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3ERauscher%2C%20Franziska%20G.%2C%20Andreas%20Hiemisch%2C%20Wieland%20Kiess%2C%20and%20Ralph%20Michael.%20%26%23x201C%3BFeasibility%20and%20Repeatability%20of%20Ocular%20Biometry%20Measured%20with%20Lenstar%20Ls%20900%20in%20a%20Large%20Group%20of%20Children%20and%20Adolescents.%26%23x201D%3B%20%3Ci%3EOphthalmic%20%26amp%3B%20Physiological%20Optics%3A%20The%20Journal%20of%20the%20British%20College%20of%20Ophthalmic%20Opticians%20%28Optometrists%29%3C%5C%2Fi%3E%2041%2C%20no.%203%20%28March%202021%29%3A%20512%26%23×2013%3B22.%20%3Ca%20class%3D%27zp-ItemURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fopo.12807%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fopo.12807%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Feasibility%20and%20Repeatability%20of%20Ocular%20Biometry%20Measured%20with%20Lenstar%20Ls%20900%20in%20a%20Large%20Group%20of%20Children%20and%20Adolescents%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Franziska%20G.%22%2C%22lastName%22%3A%22Rauscher%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andreas%22%2C%22lastName%22%3A%22Hiemisch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ralph%22%2C%22lastName%22%3A%22Michael%22%7D%5D%2C%22abstractNote%22%3A%22PURPOSE%3A%20To%20evaluate%20the%20feasibility%20and%20repeatability%20of%20Lenstar%20LS%20900%20biometry%20measurements%20in%20a%20paediatric%20population.%5CnMETHODS%3A%20Children%20were%20examined%20as%20part%20of%20the%20LIFE%20Child%20Study%20%28Leipzig%20Research%20Centre%20for%20Civilization%20Diseases%29%2C%20a%20population-based%20study%20in%20Leipzig%2C%20Germany.%20Altogether%2C%201917%20children%2C%20aged%20from%203.5%20to%2017.5%5Cu00a0years%2C%20were%20assessed%20with%20the%20Haag%20Streit%20Lenstar%20LS%20900.%20Three%20consecutive%20measurements%20of%20the%20right%20eye%20were%20analysed%20for%20axial%20length%2C%20central%20corneal%20thickness%2C%20anterior%20chamber%20depth%2C%20aqueous%20depth%2C%20lens%20thickness%20and%20flat%20and%20steep%20corneal%20radii.%20The%20number%20of%20successful%20measurements%20and%20repeatability%20were%20evaluated%20for%20each%20parameter%20and%20three%20age%20bands%20%283.5%20to%206.5%5Cu00a0years%2C%206.5%20to%2010.5%5Cu00a0years%20and%2010.5%20to%2017.5%5Cu00a0years%29.%5CnRESULTS%3A%20Best%20measurement%20feasibility%20was%20found%20for%20axial%20length%20and%20central%20corneal%20thickness%20%2891%25%20to%20100%25%29%2C%20followed%20by%20flat%20and%20steep%20corneal%20radii%20%2886%25%20to%20100%25%29%2C%20anterior%20chamber%20and%20aqueous%20depth%20%2876%25%20to%2092%25%29%20and%20lens%20thickness%20%2850%25%20to%2081%25%29%2C%20with%20higher%20numbers%20for%20older%20children.%20Repeatability%20values%20%28in%20mm%29%20were%3A%20axial%20length%200.025%20to%200.035%3B%20central%20corneal%20thickness%200.003%20to%200.027%3B%20aqueous%20depth%200.024%20to%200.058%3B%20anterior%20chamber%200.024%20to%200.054%3B%20lens%20thickness%200.034%20to%200.067.%20An%20overall%20trend%20showed%20better%20repeatability%20for%20older%20children%2C%20especially%20for%20central%20corneal%20thickness%2C%20aqueous%20depth%20and%20lens%20thickness.%5CnCONCLUSIONS%3A%20For%20ocular%20biometry%20in%20the%20paediatric%20population%2C%20axial%20length%2C%20central%20corneal%20thickness%2C%20flat%20and%20steep%20corneal%20radii%20can%20be%20measured%20very%20reliably%20even%20in%20children%20from%204%5Cu00a0years%20old%20onward%20using%20the%20Lenstar%20LS%20900.%20Lens%20thickness%20can%20be%20quantified%20in%20a%20limited%20number%20of%20younger%20children.%20Repeatability%20was%20high%20for%20all%20variables%20investigated.%20Repeatability%20improved%20with%20age%2C%20reaching%20adult%20values%20in%20the%20adolescent%20age%20band.%20Established%20repeatability%20limits%20can%20be%20applied%20in%20future%20studies%20as%20a%20quality%20parameter.%22%2C%22date%22%3A%222021-03%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1111%5C%2Fopo.12807%22%2C%22ISSN%22%3A%221475-1313%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fopo.12807%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-27T08%3A48%3A58Z%22%7D%7D%2C%7B%22key%22%3A%22T2STIT9B%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Brandt%20et%20al.%22%2C%22parsedDate%22%3A%222021-01%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EBrandt%2C%20Manuela%2C%20Carolin%20Truckenbrod%2C%20Christof%20Meigen%2C%20Mandy%20Vogel%2C%20Tanja%20Poulain%2C%20Wieland%20Kiess%2C%20and%20Siegfried%20Wahl.%20%26%23x201C%3BImpaired%20Visual%20Acuity%20Caused%20by%20Uncorrected%20Refractive%20Errors%20and%20Amblyopia%20in%20a%20German%20Paediatric%20Cohort.%26%23x201D%3B%20%3Ci%3EOphthalmic%20and%20Physiological%20Optics%3C%5C%2Fi%3E%2041%2C%20no.%201%20%28January%202021%29%3A%2042%26%23×2013%3B52.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fopo.12748%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fopo.12748%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Impaired%20Visual%20Acuity%20Caused%20by%20Uncorrected%20Refractive%20Errors%20and%20Amblyopia%20in%20a%20German%20Paediatric%20Cohort%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Manuela%22%2C%22lastName%22%3A%22Brandt%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Carolin%22%2C%22lastName%22%3A%22Truckenbrod%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christof%22%2C%22lastName%22%3A%22Meigen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Siegfried%22%2C%22lastName%22%3A%22Wahl%22%7D%5D%2C%22abstractNote%22%3A%22Purpose%20This%20study%20describes%20the%20prevalence%20of%20visual%20impairment%20caused%20by%20uncorrected%20distance%20refractive%20error%20and%20the%20spectacle%20coverage%20in%20a%20large%20cohort%20of%20German%20children%20and%20adolescents.%20Furthermore%2C%20we%20determined%20the%20prevalence%20of%20amblyopia%20and%20amblyopia%20treatment.%20Methods%20Optometrists%20carried%20out%20visual%20acuity%20%28VA%29%20testing%2C%20non-cycloplegic%20autorefraction%2C%20VA%20retesting%20with%20the%20refractive%20correction%20obtained%20by%20autorefraction%2C%20and%20if%20necessary%20subjective%20refraction%20and%20cover-test%20in%201%2C874%20subjects%20%28901%20girls%5C%2F973%20boys%29%2C%20aged%203%20to%2016%20years.%20Additionally%2C%20a%20questionnaire%20on%20the%20history%20of%20previous%20eye%20care%20was%20completed.%20Results%20Distance%20visual%20impairment%20%28VI%29%20with%20VA%20worse%20than%206%5C%2F18%20Snellen%20in%20the%20better%20eye%20was%20present%20in%200.5%25%20%2895%25%20confidence%20interval%20%5B95%25%20CI%5D%3A%200.2%25%20to%200.9%25%29%20of%20children.%20Logistic%20regression%20showed%20a%20significant%20positive%20association%20between%20VI%20and%20older%20age%20%28OR%20%3D%201.21%2C%20P%20%3D%200.03%29.%20Gender%20differences%20were%20not%20found%20%28P%20%3D%200.77%29.%20The%20spectacle%20coverage%20of%20all%20participants%20was%2074.8%25%20%2895%25%20CI%3A%2065.2%25%20to%2082.8%25%29.%20Amblyopia%20was%20found%20in%2029%20participants%20%281.5%25%3B%2095%25%20CI%3A%201.0%25%20to%202.2%25%29%20with%20no%20age%20or%20sex%20differences.%20The%20causes%20of%20unilateral%20amblyopia%20%2827%20cases%2C%2093.1%25%29%20were%20anisometropia%20in%2055.6%25%20of%20children%2C%20strabismus%20in%2025.9%25%20and%20the%20combination%20of%20these%20factors%20in%2018.5%25.%20All%20children%20with%20bilateral%20amblyopia%20%282%20cases%2C%206.9%25%29%20showed%20bilateral%20high%20ametropia.%20We%20observed%2015%20children%20with%20current%20amblyopia%2C%20who%20had%20been%20treated%20with%20occlusion%20therapy%20in%20the%20past%20%2862.2%25%3B%2095%25%20CI%3A%2042.7%25%20to%2083.6%25%29.%20Conclusions%20The%20prevalence%20of%20impaired%20VA%20caused%20by%20uncorrected%20refractive%20error%20and%20amblyopia%20is%20comparable%20with%20previous%20studies%20conducted%20in%20urban%20areas%20worldwide.%20Adding%20the%20measurement%20of%20refractive%20error%20to%20existing%20medical%20check-ups%2C%20possibly%20using%20autorefraction%2C%20would%20be%20desirable.%22%2C%22date%22%3A%222021-01%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1111%5C%2Fopo.12748%22%2C%22ISSN%22%3A%221475-1313%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fonlinelibrary.wiley.com%5C%2Fdoi%5C%2Fabs%5C%2F10.1111%5C%2Fopo.12748%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-27T08%3A36%3A33Z%22%7D%7D%2C%7B%22key%22%3A%22GCZFSJJF%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Brandt%20et%20al.%22%2C%22parsedDate%22%3A%222021%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EBrandt%2C%20Manuela%2C%20Christof%20Meigen%2C%20Carolin%20Truckenbrod%2C%20Mandy%20Vogel%2C%20Tanja%20Poulain%2C%20Anne%20Jurkutat%2C%20Franziska%20G.%20Rauscher%2C%20Wieland%20Kiess%2C%20and%20Siegfried%20Wahl.%20%26%23x201C%3BRefractive%20Status%20in%20a%20German%20Paediatric%20Cohort%3A%20A%20Cross-Sectional%20Analysis%20of%20the%20Life%20Child%20Data.%26%23x201D%3B%20%3Ci%3EOptometry%20and%20Contact%20Lenses%3C%5C%2Fi%3E%201%2C%20no.%201%20%282021%29%3A%206%26%23×2013%3B13.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.54352%5C%2Fdozv.HISM2127%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.54352%5C%2Fdozv.HISM2127%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Refractive%20Status%20in%20a%20German%20Paediatric%20Cohort%3A%20A%20Cross-Sectional%20Analysis%20of%20the%20Life%20Child%20Data%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Manuela%22%2C%22lastName%22%3A%22Brandt%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christof%22%2C%22lastName%22%3A%22Meigen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Carolin%22%2C%22lastName%22%3A%22Truckenbrod%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anne%22%2C%22lastName%22%3A%22Jurkutat%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Franziska%20G.%22%2C%22lastName%22%3A%22Rauscher%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Siegfried%22%2C%22lastName%22%3A%22Wahl%22%7D%5D%2C%22abstractNote%22%3A%22%22%2C%22date%22%3A%222021%22%2C%22language%22%3A%22%22%2C%22DOI%22%3A%2210.54352%5C%2Fdozv.HISM2127%22%2C%22ISSN%22%3A%22%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Focl-online.de%5C%2Fen%5C%2Frefractive-status-german-pediatric-cohort%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-27T08%3A36%3A19Z%22%7D%7D%2C%7B%22key%22%3A%22BYWNMEMC%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Truckenbrod%20et%20al.%22%2C%22parsedDate%22%3A%222020-03%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3ETruckenbrod%2C%20Carolin%2C%20Christof%20Meigen%2C%20Manuela%20Brandt%2C%20Mandy%20Vogel%2C%20Siegfried%20Wahl%2C%20Anne%20Jurkutat%2C%20and%20Wieland%20Kiess.%20%26%23x201C%3BReference%20Curves%20for%20Refraction%20in%20a%20German%20Cohort%20of%20Healthy%20Children%20and%20Adolescents.%26%23x201D%3B%20%3Ci%3EPLOS%20ONE%3C%5C%2Fi%3E%2015%2C%20no.%203%20%28March%202020%29%3A%20e0230291.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1371%5C%2Fjournal.pone.0230291%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1371%5C%2Fjournal.pone.0230291%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Reference%20Curves%20for%20Refraction%20in%20a%20German%20Cohort%20of%20Healthy%20Children%20and%20Adolescents%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Carolin%22%2C%22lastName%22%3A%22Truckenbrod%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christof%22%2C%22lastName%22%3A%22Meigen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Manuela%22%2C%22lastName%22%3A%22Brandt%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Siegfried%22%2C%22lastName%22%3A%22Wahl%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anne%22%2C%22lastName%22%3A%22Jurkutat%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%5D%2C%22abstractNote%22%3A%22Purpose%20Percentile%20curves%20of%20refractive%20development%20for%20German%20children%20were%20generated.%20We%20hypothesize%20that%20refraction%20in%20children%20in%20central%20Europe%20might%20differ%20from%20data%20in%20central%20Asia.%20Methods%20Non-cycloplegic%20refraction%20was%20measured%20using%20the%20ZEISS%20i.Profiler%20plus%20%28Carl%20Zeiss%20Vision%20GmbH%2C%20Germany%29%20in%201999%20children%2C%20of%20which%20were%201046%20male%20and%20953%20female%2C%20aged%203%20to%2018%20years.%20Reference%20curves%20were%20calculated%20with%20the%20R-package%20GAMLSS%20as%20continuous%20function%20of%20age.%20Results%20There%20were%20only%20little%20differences%20for%20all%20centiles%20between%20the%20genders%20at%203%20years%20and%20a%20general%20trend%20towards%20more%20myopia%20with%20increasing%20age.%20For%20the%2097th%20centile%20and%20the%203rd%20centile%2C%20girls%20showed%20higher%20myopia%5C%2F%20less%20hyperopia%20than%20boys.%20Between%20the%20age%20of%203%20and%2018%2C%20the%20median%20refraction%20became%20-0.68%20D%20and%20-0.74%20D%20more%20myopic%20for%20boys%20and%20girls%2C%20respectively.%20At%20the%20same%20time%2C%20the%2097th%20centile%20for%20boys%20changed%20%2B0.29%20D%20towards%20hyperopia%20and%20in%20girls%20-0.52%20D%20towards%20myopia.%20A%20general%20myopic%20trend%20was%20seen%20in%20the%203rd%20centile%2C%20which%20was%20-2.46%20D%20for%20boys%20and%20-2.98%20D%20for%20girls.%20For%20both%20genders%2C%20the%20median%20became%20less%20than%20zero%20at%20the%20age%20of%2010%20years%20but%20did%20not%20become%20myopic%20%28less%20than%20-0.5%20D%29%20up%20to%20the%20age%20of%2018.%20Conclusion%20Our%20analysis%20presents%20the%20first%20reference%20curve%20for%20refraction%20in%20central%20Europe.%20In%20comparison%20to%20data%20from%20China%20and%20Korea%2C%20there%20is%20only%20little%20difference%20at%20the%20age%20of%205%20years%20in%20all%20centiles%20which%20then%20increases%20continuously.%20For%20all%20ethnicities%2C%20a%20trend%20towards%20myopia%20with%20increasing%20age%20could%20be%20observed%2C%20but%20myopia%20progression%20is%20much%20higher%20in%20China%20and%20Korea%20than%20in%20Germany.%20The%20most%20marked%20differences%20can%20be%20seen%20in%20the%20lower%20centiles.%20Further%20investigations%20should%20clarify%20whether%20commencement%20of%20preschool%20activities%20with%20prolonged%20near-work%20initiates%20the%20divergence%20in%20refractive%20development.%22%2C%22date%22%3A%22Mar%2C%202020%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1371%5C%2Fjournal.pone.0230291%22%2C%22ISSN%22%3A%221932-6203%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fjournals.plos.org%5C%2Fplosone%5C%2Farticle%3Fid%3D10.1371%5C%2Fjournal.pone.0230291%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-07T07%3A01%3A22Z%22%7D%7D%2C%7B%22key%22%3A%226HMCBWPN%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Wagner%20et%20al.%22%2C%22parsedDate%22%3A%222017-02%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EWagner%2C%20Marcus%2C%20Patrick%20Scheibe%2C%20Mike%20Francke%2C%20Beatrice%20Zimmerling%2C%20Katharina%20Frey%2C%20Mandy%20Vogel%2C%20Stephan%20Luckhaus%2C%20Peter%20Wiedemann%20M.d%2C%20Wieland%20Kiess%20M.d%2C%20and%20Franziska%20G.%20Rauscher.%20%26%23x201C%3BAutomated%20Detection%20of%20the%20Choroid%20Boundary%20Within%20Oct%20Image%20Data%20Using%20Quadratic%20Measure%20Filters.%26%23x201D%3B%20%3Ci%3EJournal%20of%20Biomedical%20Optics%3C%5C%2Fi%3E%2022%2C%20no.%202%20%28February%202017%29%3A%20025004.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1117%5C%2F1.JBO.22.2.025004%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1117%5C%2F1.JBO.22.2.025004%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Automated%20Detection%20of%20the%20Choroid%20Boundary%20Within%20Oct%20Image%20Data%20Using%20Quadratic%20Measure%20Filters%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Marcus%22%2C%22lastName%22%3A%22Wagner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Patrick%22%2C%22lastName%22%3A%22Scheibe%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mike%22%2C%22lastName%22%3A%22Francke%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Beatrice%22%2C%22lastName%22%3A%22Zimmerling%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Katharina%22%2C%22lastName%22%3A%22Frey%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Stephan%22%2C%22lastName%22%3A%22Luckhaus%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Peter%20Wiedemann%22%2C%22lastName%22%3A%22M.d%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%20Kiess%22%2C%22lastName%22%3A%22M.d%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Franziska%20G.%22%2C%22lastName%22%3A%22Rauscher%22%7D%5D%2C%22abstractNote%22%3A%22A%20novel%20method%20for%20the%20automated%20detection%20of%20the%20outer%20choroid%20boundary%20within%20spectral-domain%20optical%20coherence%20tomography%20image%20data%2C%20based%20on%20an%20image%20model%20within%20the%20space%20of%20functions%20of%20bounded%20variation%20and%20the%20application%20of%20quadratic%20measure%20filters%2C%20is%20presented.%20The%20same%20method%20is%20used%20for%20the%20segmentation%20of%20retinal%20layer%20boundaries%20and%20proves%20to%20be%20suitable%20even%20for%20data%20generated%20without%20special%20imaging%20modes%20and%20moderate%20line%20averaging.%20Based%20on%20the%20segmentations%2C%20an%20automated%20determination%20of%20the%20central%20fovea%20region%20and%20choroidal%20thickness%20measurements%20for%20this%20and%20two%20adjacent%201-mm%20regions%20are%20provided.%20The%20quality%20of%20the%20method%20is%20assessed%20by%20comparison%20with%20manual%20delineations%20performed%20by%20five%20trained%20graders.%20The%20study%20is%20based%20on%20data%20from%2050%20children%20of%20the%20ages%208%20to%2013%20that%20were%20obtained%20in%20the%20framework%20of%20the%20LIFE%20Child%20study%20at%20Leipzig%20University.%22%2C%22date%22%3A%22February%202017%22%2C%22language%22%3A%22%22%2C%22DOI%22%3A%2210.1117%5C%2F1.JBO.22.2.025004%22%2C%22ISSN%22%3A%221083-3668%2C%201560-2281%22%2C%22url%22%3A%22http%3A%5C%2F%5C%2Fwww.spiedigitallibrary.org%5C%2Fjournals%5C%2FJournal-of-Biomedical-Optics%5C%2Fvolume-22%5C%2Fissue-2%5C%2F025004%5C%2FAutomated-detection-of-the-choroid-boundary-within-OCT-image-data%5C%2F10.1117%5C%2F1.JBO.22.2.025004.short%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-27T09%3A00%3A33Z%22%7D%7D%5D%7D
Rauscher, Franziska G., Andreas Hiemisch, Wieland Kiess, and Ralf Blendowske. “Monochromatic Ocular High-Order Aberrations in Children and Adolescents.” Ophthalmic & Physiological Optics: The Journal of the British College of Ophthalmic Opticians (Optometrists) 43, no. 4 (July 2023): 842–59. https://doi.org/10.1111/opo.13151.
Söhnel, Tanja, Christof Meigen, Andreas Hiemisch, Siegfried Wahl, Focke Ziemssen, Carolin Truckenbrod, Katharina Hübner, and Wieland Kiess. “Normative Data for Macular and Retinal Nerve Fibre Layer Thickness in Healthy German Children and Adolescents Using Optical Coherence Tomography.” Ophthalmic and Physiological Optics, March 17, 2023, opo.13123. https://doi.org/10.1111/opo.13123.
Philipp, Dariusch, Mandy Vogel, Manuela Brandt, Franziska G. Rauscher, Andreas Hiemisch, Siegfried Wahl, Wieland Kiess, and Tanja Poulain. “The Relationship between Myopia and near Work, Time Outdoors and Socioeconomic Status in Children and Adolescents.” BMC Public Health 22, no. 1 (November 10, 2022): 2058. https://doi.org/10.1186/s12889-022-14377-1.
Rauscher, Franziska G., Mike Francke, Andreas Hiemisch, Wieland Kiess, and Ralph Michael. “Ocular Biometry in Children and Adolescents from 4 to 17 Years: A Cross-Sectional Study in Central Germany.” Ophthalmic and Physiological Optics 41, no. 3 (May 2021): 496–511. https://doi.org/10.1111/opo.12814.
Truckenbrod, Carolin, Christof Meigen, Manuela Brandt, Mandy Vogel, Pablo Sanz Diez, Siegfried Wahl, Anne Jurkutat, and Wieland Kiess. “Longitudinal Analysis of Axial Length Growth in a German Cohort of Healthy Children and Adolescents.” Ophthalmic & Physiological Optics: The Journal of the British College of Ophthalmic Opticians (Optometrists) 41, no. 3 (May 2021): 532–40. https://doi.org/10.1111/opo.12817.
Rauscher, Franziska G., Andreas Hiemisch, Wieland Kiess, and Ralph Michael. “Feasibility and Repeatability of Ocular Biometry Measured with Lenstar Ls 900 in a Large Group of Children and Adolescents.” Ophthalmic & Physiological Optics: The Journal of the British College of Ophthalmic Opticians (Optometrists) 41, no. 3 (March 2021): 512–22. https://doi.org/10.1111/opo.12807.
Brandt, Manuela, Carolin Truckenbrod, Christof Meigen, Mandy Vogel, Tanja Poulain, Wieland Kiess, and Siegfried Wahl. “Impaired Visual Acuity Caused by Uncorrected Refractive Errors and Amblyopia in a German Paediatric Cohort.” Ophthalmic and Physiological Optics 41, no. 1 (January 2021): 42–52. https://doi.org/10.1111/opo.12748.
Brandt, Manuela, Christof Meigen, Carolin Truckenbrod, Mandy Vogel, Tanja Poulain, Anne Jurkutat, Franziska G. Rauscher, Wieland Kiess, and Siegfried Wahl. “Refractive Status in a German Paediatric Cohort: A Cross-Sectional Analysis of the Life Child Data.” Optometry and Contact Lenses 1, no. 1 (2021): 6–13. https://doi.org/10.54352/dozv.HISM2127.
Truckenbrod, Carolin, Christof Meigen, Manuela Brandt, Mandy Vogel, Siegfried Wahl, Anne Jurkutat, and Wieland Kiess. “Reference Curves for Refraction in a German Cohort of Healthy Children and Adolescents.” PLOS ONE 15, no. 3 (March 2020): e0230291. https://doi.org/10.1371/journal.pone.0230291.
Wagner, Marcus, Patrick Scheibe, Mike Francke, Beatrice Zimmerling, Katharina Frey, Mandy Vogel, Stephan Luckhaus, Peter Wiedemann M.d, Wieland Kiess M.d, and Franziska G. Rauscher. “Automated Detection of the Choroid Boundary Within Oct Image Data Using Quadratic Measure Filters.” Journal of Biomedical Optics 22, no. 2 (February 2017): 025004. https://doi.org/10.1117/1.JBO.22.2.025004.
2390247
T52N9QLZ
zahn
1
chicago-fullnote-bibliography
50
date
desc
1
1
6748
https://home.uni-leipzig.de/lifechild/wp-content/plugins/zotpress/
%7B%22status%22%3A%22success%22%2C%22updateneeded%22%3Afalse%2C%22instance%22%3Afalse%2C%22meta%22%3A%7B%22request_last%22%3A0%2C%22request_next%22%3A0%2C%22used_cache%22%3Atrue%7D%2C%22data%22%3A%5B%7B%22key%22%3A%2283E3XT9F%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Hirsch%20et%20al.%22%2C%22parsedDate%22%3A%222023%22%2C%22numChildren%22%3A2%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EHirsch%2C%20Christian%2C%20Oliver%20Schierz%2C%20Antje%20K%26%23xF6%3Brner%2C%20Wieland%20Kiess%2C%20Ronald%20Biemann%2C%20Annett%20Schrock%2C%20and%20Jens%20Christoph%20T%26%23xFC%3Brp.%20%26%23x201C%3BSex%20Hormones%20Associated%20with%20Temporomandibular%20Pain%20on%20Palpation%20in%20Male%20Adolescents%26%23×2014%3BResults%20of%20the%20Epidemiologic%20LIFE%20Child%20Study.%26%23x201D%3B%20%3Ci%3EJournal%20of%20Oral%20Rehabilitation%3C%5C%2Fi%3E%20n%5C%2Fa%2C%20no.%20n%5C%2Fa%20%282023%29.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fjoor.13530%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fjoor.13530%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Sex%20hormones%20associated%20with%20temporomandibular%20pain%20on%20palpation%20in%20male%20adolescents%5Cu2014Results%20of%20the%20epidemiologic%20LIFE%20child%20study%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christian%22%2C%22lastName%22%3A%22Hirsch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Oliver%22%2C%22lastName%22%3A%22Schierz%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ronald%22%2C%22lastName%22%3A%22Biemann%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Annett%22%2C%22lastName%22%3A%22Schrock%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jens%20Christoph%22%2C%22lastName%22%3A%22T%5Cu00fcrp%22%7D%5D%2C%22abstractNote%22%3A%22Objective%20This%20study%20aimed%20to%20investigate%20whether%20the%20sex%20steroid%20precursor%20hormone%20dehydroepiandrosterone%20sulphate%20%28DHEA-S%29%2C%20sex%20hormone-binding%20globulin%20%28SHBG%29%20and%20testosterone%20%28TT%29%20are%20associated%20with%20temporomandibular%20%28TM%29%20pain%20on%20palpation%20in%20male%20adolescents.%20Methods%20Out%20of%20the%20LIFE%20Child%20study%20dataset%20containing%201022%20children%20and%20adolescents%20aged%2010%5Cu201318%20years%20%28496%20males%2C%2048.5%25%29%2C%20we%20used%20a%20subsample%20of%20273%20male%20adolescents%20%28mean%20age%3A%2013.8%20%5Cu00b1%202.3%20years%29%20in%20advanced%20pubertal%20development%20%28PD%29%20to%20analyse%20the%20association%20between%20hormones%20and%20TM%20pain.%20The%20Tanner%20scale%20was%20applied%20to%20describe%20the%20stage%20of%20PD.%20Pain%20on%20palpation%20of%20the%20temporalis%20and%20masseter%20muscles%20and%20the%20TM%20joints%20%28palpation%20pain%29%20was%20assessed%20using%20the%20Diagnostic%20Criteria%20for%20Temporomandibular%20Disorders%20%28DC%5C%2FTMD%29.%20Serum%20levels%20of%20sex%20hormones%20%28DHEA-S%2C%20SHBG%20and%20TT%29%20were%20determined%20using%20standardised%20laboratory%20analyses.%20Free%20TT%20was%20estimated%20from%20the%20ratio%20between%20TT%20and%20SHBG%20%28free%20androgen%20index%5BFAI%5D%29.%20We%20calculated%20the%20risk%20of%20perceived%20positive%20palpation%20pain%20for%20male%20participants%20as%20a%20function%20of%20hormone%20levels%20%28DHEA-S%2C%20FAI%29%20taking%20into%20account%20age%20and%20body%20mass%20index%20%28BMI%29.%20Results%20Among%20more%20developed%20%28Tanner%20stage%204%5Cu20135%29%20male%20adolescents%2C%2022.7%25%20%28n%20%3D%2062%29%20reported%20palpation%20pain%20in%20the%20TM%20region.%20In%20these%20participants%2C%20FAI%20levels%20were%20approximately%20half%20that%20of%20individuals%20without%20such%20pain%20%28p%20%3C%20.01%29.%20DHEA-S%20levels%20were%20about%2030%25%20lower%20in%20the%20pain%20group%20%28p%20%3C%20.01%29.%20In%20multivariable%20regression%20analyses%2C%20the%20odds%20ratio%20%28OR%29%20for%20pain%20on%20palpation%20decreased%20to%200.75%20%2895%25%20confidence%20interval%20%5BCI%5D%3A%200.57%5Cu20130.98%29%20per%2010%20units%20of%20FAI%20level%20compared%20to%20those%20without%20pain%2C%20after%20controlling%20for%20the%20effects%20of%20age%20and%20adjusted%20BMI.%20We%20observed%20the%20same%20effect%20for%20this%20subgroup%20per%20unit%20of%20DHEA-S%20serum%20level%20%28OR%20%3D%200.71%3B%2095%25%20CI%3A%200.53%5Cu20130.94%29.%20Conclusion%20At%20subclinical%20lower%20levels%20of%20serum%20free%20TT%20and%20DHEA-S%2C%20male%20adolescents%20are%20more%20likely%20to%20report%20pain%20on%20standardised%20palpation%20of%20the%20masticatory%20muscles%20and%5C%2For%20TM%20joints.%20This%20finding%20supports%20the%20hypothesis%20that%20sex%20hormones%20may%20influence%20pain%20reporting.%22%2C%22date%22%3A%222023%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1111%5C%2Fjoor.13530%22%2C%22ISSN%22%3A%221365-2842%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fonlinelibrary.wiley.com%5C%2Fdoi%5C%2Fabs%5C%2F10.1111%5C%2Fjoor.13530%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-24T08%3A49%3A13Z%22%7D%7D%2C%7B%22key%22%3A%22EV7HF6VS%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Buchhardt%20et%20al.%22%2C%22parsedDate%22%3A%222022-06-22%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EBuchhardt%2C%20Jeanette%2C%20Wieland%20Kiess%2C%20Antje%20K%26%23xF6%3Brner%2C%20Ronald%20Biemann%2C%20Christian%20Hirsch%2C%20and%20Life%20Child%20Study%20Team.%20%26%23x201C%3BThe%20Influence%20of%20Steroid%20Hormones%20on%20Tooth%20Wear%20in%20Children%20and%20in%20Adolescents.%26%23x201D%3B%20%3Ci%3EJournal%20of%20Clinical%20Medicine%3C%5C%2Fi%3E%2011%2C%20no.%2013%20%28June%2022%2C%202022%29%3A%203603.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Fjcm11133603%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Fjcm11133603%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22The%20Influence%20of%20Steroid%20Hormones%20on%20Tooth%20Wear%20in%20Children%20and%20in%20Adolescents%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jeanette%22%2C%22lastName%22%3A%22Buchhardt%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ronald%22%2C%22lastName%22%3A%22Biemann%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christian%22%2C%22lastName%22%3A%22Hirsch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Life%22%2C%22lastName%22%3A%22Child%20Study%20Team%22%7D%5D%2C%22abstractNote%22%3A%22%281%29%20Background%3A%20From%20a%20young%20age%2C%20boys%20are%20more%20often%20affected%20by%20tooth%20wear%20than%20girls.%20This%20suggests%20an%20influence%20of%20the%20male%20sex%20hormone%20%28testosterone%29%20on%20the%20aetiology%20of%20tooth%20wear.%20The%20aim%20of%20the%20present%20study%20was%20to%20investigate%20the%20incidence%20of%20tooth%20wear%20in%20relation%20to%20steroid%20hormone%20levels%20in%20children.%20%282%29%20Methods%3A%201022%20test%20persons%20aged%20between%2010%20and%2018%20%28491%20male%2C%20531%20female%29%20from%20the%20LIFE%20Child%20study%20underwent%20medical%20and%20dental%20examination.%20Tooth%20wear%20was%20measured%20through%20clinical%20inspection.%20Blood%20samples%20were%20taken%20to%20determine%20hormone%20levels%20%28testosterone%2C%20SHBG%29.%20The%20level%20of%20free%20testosterone%20was%20calculated%20from%20the%20ratio%20of%20testosterone%20to%20SHBG.%20Using%20multivariable%20methods%2C%20the%20incidence%20of%20tooth%20wear%20was%20analyzed%20as%20a%20function%20of%20hormone%20levels%2C%20while%20controlling%20for%20confounders%20such%20as%20age%2C%20sex%2C%20social%20status%2C%20and%20orthodontic%20treatment.%20%283%29%20Results%3A%20The%20incidence%20of%20tooth%20wear%20increased%20with%20age%20in%20both%20sexes.%20Boys%20showed%20significantly%20more%20often%20attrition%20facets%20than%20girls%20%2817.5%25%20vs.%2013.2%25%2C%20p%20%26lt%3B%200.001%29.%20Subjects%20with%20tooth%20wear%20showed%20significantly%20higher%20free%20testosterone%20levels%20than%20those%20without%20%28males%3A%20p%20%26lt%3B%200.001%2C%20females%3A%20p%20%26lt%3B%200.05%29.%20After%20controlling%20for%20confounding%20variables%2C%20the%20risk%20of%20tooth%20wear%20increased%20by%20approximately%2030.0%25%20with%20each%20year%20of%20life%20%28odds%20ratio%20%5BOR%5Dboys%20%3D%201.29%2C%2095%25%20confidence%20interval%20%5BCI%5D%20%3D%201.04-1.56%3B%20%5BOR%5Dgirls%20%3D%201.32%2C%2095%25%20CI%20%3D%201.08-1.61%29.%20In%20addition%2C%20the%20risk%20of%20tooth%20wear%20increased%20by%206.0%25%20per%20free%20testosterone%20scale%20score%20only%20in%20boys%20%28OR%20%3D%201.06%2C%2095%25%20CI%20%3D%201.01-1.12%29.%20%284%29%20Conclusions%3A%20Tooth%20wear%20is%20common%20in%20children%20and%20in%20adolescents%2C%20and%20it%20increases%20steadily%20with%20age%20in%20both%20sexes.%20The%20stronger%20increase%20and%20the%20higher%20prevalence%20among%20male%20adolescents%20can%20be%20explained%20by%20the%20additional%20effect%20of%20free%20testosterone.%22%2C%22date%22%3A%222022-06-22%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.3390%5C%2Fjcm11133603%22%2C%22ISSN%22%3A%222077-0383%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-23T10%3A52%3A50Z%22%7D%7D%2C%7B%22key%22%3A%22JIP2SVQ8%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Kolbow%20et%20al.%22%2C%22parsedDate%22%3A%222022-01%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EKolbow%2C%20Henrike%2C%20Wieland%20Kiess%2C%20Christian%20Hirsch%2C%20Mandy%20Vogel%2C%20Annett%20Schrock%2C%20and%20Wieland%20Elger.%20%26%23x201C%3BThe%20Influence%20of%20Coordinative%20Skills%20on%20the%20Oral%20Health%20of%20Children%20and%20Adolescents%20in%20Permanent%20Dentition.%26%23x201D%3B%20%3Ci%3EJournal%20of%20Clinical%20Medicine%3C%5C%2Fi%3E%2011%2C%20no.%2021%20%28January%202022%29%3A%206472.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Fjcm11216472%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Fjcm11216472%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22The%20Influence%20of%20Coordinative%20Skills%20on%20the%20Oral%20Health%20of%20Children%20and%20Adolescents%20in%20Permanent%20Dentition%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Henrike%22%2C%22lastName%22%3A%22Kolbow%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christian%22%2C%22lastName%22%3A%22Hirsch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Annett%22%2C%22lastName%22%3A%22Schrock%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Elger%22%7D%5D%2C%22abstractNote%22%3A%22Removing%20dental%20plaque%20by%20using%20a%20toothbrush%20is%20the%20most%20important%20measure%20for%20oral%20hygiene.%20The%20aim%20of%20the%20present%20study%20was%20to%20estimate%20the%20impact%20of%20the%20coordination%20skills%20of%20children%20and%20adolescents%20on%20their%20oral%20health%20%28plaque%20level%2C%20DMF%5C%2FT%3A%20decayed%2C%20missing%2C%20filled%20teeth%29.%20Within%20a%20prospective%20cohort%20study%2C%20996%20children%20%2810%20to%2018%20years%29%20were%20examined.%20The%20results%20of%20three%20coordination%20tests%20from%20the%20Motorik%20Modul%20%28MoMo%29%20were%20included%20to%20evaluate%20the%20coordination%20skills.%20Other%20parameters%20taken%20into%20account%20were%20age%2C%20sex%2C%20orthodontic%20treatment%20and%20socioeconomic%20status%20%28SES%29.%20Univariate%20and%20various%20multivariate%20analyses%20were%20performed%20to%20evaluate%20relationships.%20Better%20results%20in%20precision%20coordination%20tests%20were%20significantly%20related%20to%20a%20better%20oral%20hygiene%20%28backward%20balancing%3A%20logistic%20regression%20OR%200.86%2C%2095%25CI%3A%200.73%5Cu20130.99%2C%20p%20%3D%200.051%2C%20proportional%20odds%20model%20OR%200.86%2C%2095%25CI%3A%200.75%5Cu20130.99%2C%20p%20%3D%200.037%3B%20one-leg-stand%3A%20logistic%20regression%20OR%200.78%2C%2095%25CI%3A%200.63%5Cu20130.96%2C%20p%20%3D%200.018%2C%20proportional%20odds%20model%20OR%200.77%2C%2095%25CI%3A%200.64%5Cu20130.92%2C%20p%20%3D%200.003%29.%20Higher%20scores%20on%20one-leg-stand%20were%20significantly%20related%20to%20a%20lower%20caries%20prevalence%20%28logistic%20regression%20OR%200.81%2C%2095%25CI%3A%200.66%5Cu20130.99%2C%20p%20%3D%200.037%3B%20Poisson%20regression%20exp%28%5Cu00df%29%200.82%2C%2095%25CI%3A%200.74%5Cu20130.91%2C%20p%20%3C%200.001%29.%20Coordination%20test%20under%20a%20time%20constraint%20%28jumping%20side-to-side%29%20showed%20no%20significant%20relation.%20Oral%20hygiene%20was%20poorer%20in%20younger%20children%2C%20boys%20and%20low%20SES.%20Caries%20prevalence%20increased%20with%20low%20SES%20and%20increasing%20age.%20The%20present%20results%20suggest%20that%20oral%20health%20is%20influenced%20by%20coordinative%20skills.%22%2C%22date%22%3A%222022%5C%2F1%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.3390%5C%2Fjcm11216472%22%2C%22ISSN%22%3A%222077-0383%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.mdpi.com%5C%2F2077-0383%5C%2F11%5C%2F21%5C%2F6472%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-24T09%3A11%3A53Z%22%7D%7D%2C%7B%22key%22%3A%22R2F3DZ8S%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Schmidt%20et%20al.%22%2C%22parsedDate%22%3A%222022-01%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3ESchmidt%2C%20Jana%2C%20Mandy%20Vogel%2C%20Tanja%20Poulain%2C%20Wieland%20Kiess%2C%20Christian%20Hirsch%2C%20Dirk%20Ziebolz%2C%20and%20Rainer%20Haak.%20%26%23x201C%3BAssociation%20of%20Oral%20Health%20Conditions%20in%20Adolescents%20with%20Social%20Factors%20and%20Obesity.%26%23x201D%3B%20%3Ci%3EInternational%20Journal%20of%20Environmental%20Research%20and%20Public%20Health%3C%5C%2Fi%3E%2019%2C%20no.%205%20%28January%202022%29%3A%202905.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Fijerph19052905%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Fijerph19052905%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Association%20of%20Oral%20Health%20Conditions%20in%20Adolescents%20with%20Social%20Factors%20and%20Obesity%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jana%22%2C%22lastName%22%3A%22Schmidt%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christian%22%2C%22lastName%22%3A%22Hirsch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Dirk%22%2C%22lastName%22%3A%22Ziebolz%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Rainer%22%2C%22lastName%22%3A%22Haak%22%7D%5D%2C%22abstractNote%22%3A%22This%20study%20aimed%20to%20investigate%20associations%20between%20psychosocial%20factors%2C%20obesity%2C%20and%20oral%20health%20in%20a%20study%20population%20of%2010-%20to%2018-year-old%20adolescents%20who%20participated%20in%20the%20LIFE%20Child%20study.%20Psychosocial%20information%20%28socioeconomic%20status%20%28SES%29%20based%20on%20parents%5Cu2019%20education%2C%20occupation%20and%20household%20income%2C%20Strengths%20and%20Difficulties%20Questionnaire%20%28SDQ%29%2C%20health-related%20quality%20of%20life%29%20and%20physical%20activity%20behavior%20were%20obtained.%20Nutritional%20status%20was%20classified%20based%20on%20age-%20and%20sex-adjusted%20body%20mass%20index%20into%20underweight%2C%20overweight%2C%20normal%20weight%20and%20obese.%20Clinical%20dental%20examinations%20were%20performed%20and%20scored%20with%20respect%20to%20caries%20experience%20%28CE%29%2C%20oral%20hygiene%20%28OH%29%2C%20and%20periodontal%20status%20%28periodontal%20health%20score%3A%20PERIO-S%29.%20Age-adjusted%20regression%20analysis%20under%20the%20assumption%20of%20a%20double%20Poisson%20distribution%20was%20performed%20with%20and%20without%20adjusting%20for%20SES%20%28%5Cu03b1%20%3D%205%25%29.%20A%20total%20of%201158%20study%20participants%20%28590%20girls%2C%20568%20boys%3B%20mean%20age%2013.2%20%5Cu00b1%202.3%20years%29%20were%20included%20%2817.2%25%20were%20classified%20as%20obese%29.%20CE%20was%2020%25%20higher%20for%20moderate%20and%2060%25%20higher%20for%20low%20SES%20compared%20to%20high%20SES%20%28p%20%3C%200.05%29.%20PERIO-S%20was%2010%25%20higher%20for%20moderate%20and%2030%25%20higher%20for%20low%20compared%20to%20high%20SES%20%28p%20%3C%200.05%29.%20Poor%20OH%20was%20associated%20with%20higher%20CE%20%28Ratio%20R%20%3D%202.3%2C%20p%20%3C%200.0001%29%20and%20PERIO-S%20%28R%20%3D%203.1%2C%20p%20%3C%200.0001%29.%20Physical%20activity%20in%20a%20sports%20club%20was%20associated%20with%20lower%20CE-S%20and%20PERIO-S%20%28R%20%3D%200.85%2C%20p%20%3C%200.001%29.%20Obesity%20was%20associated%20with%20increased%20CE%20%28R%20%3D%201.3%2C%20p%20%3C%200.001%29%20compared%20to%20normal%20weight.%20For%20low%20but%20not%20high%20SES%2C%20more%20reported%20difficulties%20were%20associated%20with%20higher%20CE.%20In%20conclusion%2C%20low%20SES%2C%20poor%20OH%2C%20and%20obesity%20are%20associated%20with%20unfavorable%20oral%20health%20conditions%2C%20whereas%20physical%20activity%20and%20high%20SES%20are%20potentially%20protective.%22%2C%22date%22%3A%222022%5C%2F1%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.3390%5C%2Fijerph19052905%22%2C%22ISSN%22%3A%221660-4601%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.mdpi.com%5C%2F1660-4601%5C%2F19%5C%2F5%5C%2F2905%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-24T11%3A21%3A50Z%22%7D%7D%2C%7B%22key%22%3A%22RRKTRHP8%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Rauch%20et%20al.%22%2C%22parsedDate%22%3A%222020-11%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3ERauch%2C%20Angelika%2C%20Antje%20K%26%23xF6%3Brner%2C%20Wieland%20Kiess%2C%20Christian%20Hirsch%2C%20and%20Oliver%20Schierz.%20%26%23x201C%3BRelationship%20between%20Age-Dependent%20Body%20Constitution%20and%20Temporomandibular%20Joint%20Sounds%20in%20Adolescents.%26%23x201D%3B%20%3Ci%3EJournal%20of%20Clinical%20Medicine%3C%5C%2Fi%3E%209%2C%20no.%2011%20%28November%202020%29%3A%203927.%20%3Ca%20class%3D%27zp-ItemURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Fjcm9123927%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Fjcm9123927%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Relationship%20between%20Age-Dependent%20Body%20Constitution%20and%20Temporomandibular%20Joint%20Sounds%20in%20Adolescents%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Angelika%22%2C%22lastName%22%3A%22Rauch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christian%22%2C%22lastName%22%3A%22Hirsch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Oliver%22%2C%22lastName%22%3A%22Schierz%22%7D%5D%2C%22abstractNote%22%3A%22To%20date%2C%20risk%20factors%20for%20temporomandibular%20joint%20%28TMJ%29%20sounds%20are%20still%20not%20completely%20understood%2C%20and%20anatomical%20factors%20are%20suspected%20to%20in%5Cufb02uence%20their%20occurrence.%20This%20study%20aimed%20to%20evaluate%20the%20impact%20of%20body%20constitution%20on%20temporomandibular%20joint%20sounds%20of%20adolescents.%2010-%20to%2018-year-old%20participants%20of%20the%20LIFE%20Child%20Study%20were%20examined%20for%20TMJ%20sounds%2C%20and%20physical%20parameters%20such%20as%20body%20height%2C%20body%20weight%2C%20and%20general%20laxity%20of%20joints%20were%20measured.%20Odds%20ratios%20%28OR%29%20for%20associations%20of%20TMJ%20sounds%20and%20standard%20deviation%20scores%20%28SDS%29%20of%20body%20height%20and%20body%20weight%20were%20calculated%20by%20using%20binary%20logistic%20regression%2C%20including%20cofactors%20such%20as%20age%20and%20number%20of%20hypermobile%20joints.%20The%20OR%20for%20TMJ%20sounds%20and%20SDS%20of%20body%20height%20was%201.28%20%2895%25%20con%5Cufb01dence%20interval%20%28CI%29%201.06%3B%201.56%29%20in%20females%20when%20the%20age-adjusted%20height%20value%20was%20above%200.%20SDS%20of%20body%20weight%20indicated%20signi%5Cufb01cant%20ORs%20for%20TMJ%20sounds%20in%20males%20with%20values%20of%200.81%20%2895%25%20CI%200.70%3B%200.94%29.%20No%20correlation%20was%20detected%20for%20SDS%20values%20and%20TMJ%20crepitus.%20Tall%20female%20adolescents%20seem%20to%20be%20more%20prone%20to%20TMJ%20clicking%20sounds%2C%20while%20their%20occurrence%20seems%20less%20likely%20in%20male%20adolescents%20with%20higher%20body%20weight.%22%2C%22date%22%3A%222020-11%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.3390%5C%2Fjcm9123927%22%2C%22ISSN%22%3A%22%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Fjcm9123927%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-07T07%3A01%3A30Z%22%7D%7D%2C%7B%22key%22%3A%22MCGV96MP%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Elger%20et%20al.%22%2C%22parsedDate%22%3A%222020-08%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EElger%2C%20Wieland%2C%20Christina%20Illge%2C%20Wieland%20Kiess%2C%20Antje%20K%26%23xF6%3Brner%2C%20J%26%23xFC%3Brgen%20Kratzsch%2C%20Annett%20Schrock%2C%20and%20Christian%20Hirsch.%20%26%23x201C%3BRelationship%20Between%20Deciduous%20Molar%20Hypomineralisation%20and%20Parameters%20of%20Bone%20Metabolism%20in%20Preschool%20Children.%26%23x201D%3B%20%3Ci%3EInternational%20Dental%20Journal%3C%5C%2Fi%3E%2070%2C%20no.%204%20%28August%202020%29%3A%20303%26%23×2013%3B7.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fidj.12550%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fidj.12550%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Relationship%20Between%20Deciduous%20Molar%20Hypomineralisation%20and%20Parameters%20of%20Bone%20Metabolism%20in%20Preschool%20Children%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Elger%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christina%22%2C%22lastName%22%3A%22Illge%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J%5Cu00fcrgen%22%2C%22lastName%22%3A%22Kratzsch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Annett%22%2C%22lastName%22%3A%22Schrock%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christian%22%2C%22lastName%22%3A%22Hirsch%22%7D%5D%2C%22abstractNote%22%3A%22BACKGROUND%3A%20The%20aetiology%20of%20deciduous%20molar%20hypomineralisation%20%28DMH%29%20is%20still%20largely%20unknown.%5CnAIM%3A%20The%20aim%20of%20the%20study%20was%20to%20elucidate%20the%20occurrence%20of%20DMH%20as%20a%20function%20of%20the%20parameters%20of%20bone%20metabolism%2C%20as%20it%20is%20suspected%20that%20abnormalities%20in%20these%20parameters%20may%20affect%20the%20mineralisation%20of%20teeth.%5CnDESIGN%3A%20In%20a%20prospective%20cohort%20study%2C%20958%20children%20aged%201-6%5Cu00a0years%20were%20examined.%20The%20inclusion%20criteria%20were%3A%20a%20blood%20sample%20to%20determine%20the%20parameters%20of%20bone%20metabolism%3B%20and%20documentation%20of%20enamel%20mineralisation%20using%20the%20European%20Academy%20of%20Paediatric%20Dentistry%20%28EAPD%29%20criteria.%20Multivariable%20methods%20were%20applied%20to%20analyse%20the%20incidence%20of%20DMH%20relative%20to%20the%20concentrations%20of%20serum%20calcium%2C%20phosphate%2C%20vitamin%20D%2C%20vitamin%20B12%20and%20alkaline%20phosphatase%2C%20taking%20into%20account%20the%20effects%20of%20age%2C%20gender%20and%20height.%5CnRESULTS%3A%20The%20proportion%20of%20children%20diagnosed%20with%20DMH%20was%204.0%25%20%2838%20of%20958%29.%20A%20significant%20difference%20between%20DMH-affected%20and%20non-DMH-affected%20children%20was%20found%20only%20in%20the%20serum%20concentration%20of%20calcium%20%282.47%5Cu00a0%5Cu00b1%5Cu00a00.08%5Cu00a0mmol%5C%2Fl%20vs.%202.52%5Cu00a0%5Cu00b1%5Cu00a00.10%5Cu00a0mmol%5C%2Fl%2C%20respectively%2C%20P%5Cu00a0%3D%5Cu00a00.004%29.%20The%20risk%20of%20DMH%20significantly%20increased%2C%20by%201.63-fold%20%2895%25%20CI%3A%201.03-2.57%29%2C%20if%20the%20calcium%20level%20dropped%20by%200.1%5Cu00a0mmol%5C%2Fl%2C%20regardless%20of%20age%2C%20gender%20or%20adjusted%20height.%20During%20the%20follow-up%20examination%20of%2017%20DMH-affected%20subjects%2C%20the%20calcium%20level%20remained%20consistently%20low%201%5Cu00a0year%20later%20%28t-test%2C%20P%5Cu00a0%3E%5Cu00a00.05%29.%5CnCONCLUSION%3A%20Children%20with%20DMH%20showed%20consistently%20subclinically%20lower%20serum%20calcium%20levels.%20No%20associations%20were%20found%20for%20other%20parameters.%22%2C%22date%22%3A%22Aug%202020%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1111%5C%2Fidj.12550%22%2C%22ISSN%22%3A%221875-595X%22%2C%22url%22%3A%22http%3A%5C%2F%5C%2Forgid.org%5C%2F10.1111%5C%2Fidj.12550%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-23T13%3A50%3A21Z%22%7D%7D%2C%7B%22key%22%3A%22LBTQGTMJ%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Rauch%20et%20al.%22%2C%22parsedDate%22%3A%222020-04%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3ERauch%2C%20Angelika%2C%20Oliver%20Schierz%2C%20Antje%20K%26%23xF6%3Brner%2C%20Wieland%20Kiess%2C%20and%20Christian%20Hirsch.%20%26%23x201C%3BPrevalence%20of%20Anamnestic%20Symptoms%20and%20Clinical%20Signs%20of%20Temporomandibular%20Disorders%20in%20Adolescents-Results%20of%20the%20Epidemiologic%20Life%20Child%20Study.%26%23x201D%3B%20%3Ci%3EJournal%20of%20Oral%20Rehabilitation%3C%5C%2Fi%3E%2047%2C%20no.%204%20%28April%202020%29%3A%20425%26%23×2013%3B31.%20%3Ca%20class%3D%27zp-ItemURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fjoor.12926%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fjoor.12926%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Prevalence%20of%20Anamnestic%20Symptoms%20and%20Clinical%20Signs%20of%20Temporomandibular%20Disorders%20in%20Adolescents-Results%20of%20the%20Epidemiologic%20Life%20Child%20Study%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Angelika%22%2C%22lastName%22%3A%22Rauch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Oliver%22%2C%22lastName%22%3A%22Schierz%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christian%22%2C%22lastName%22%3A%22Hirsch%22%7D%5D%2C%22abstractNote%22%3A%22BACKGROUND%3A%20Prevalence%20values%20for%20symptoms%20and%20signs%20of%20temporomandibular%20disorders%20%28TMD%29%20in%20adolescents%20vary%20within%20the%20literature%20due%20to%20differences%20in%20set-ups%20of%20examination%20protocols.%5CnOBJECTIVES%3A%20The%20objective%20was%20to%20present%20prevalence%20values%20for%20symptoms%20and%20signs%20of%20TMD%20in%20German%20adolescents%20that%20were%20observed%20within%20a%20standardised%20examination.%20Prevalence%20values%20comparing%20gender%20or%20pubertal%20status%20should%20be%20investigated.%5CnMETHODS%3A%20A%20cross-sectional%20sample%20of%20the%20LIFE%20Child%20Study%20aged%2010%20to%2018%20was%20examined.%20A%20questionnaire%20gathering%20anamnestic%20symptoms%20of%20TMD%20was%20completed%2C%20and%20an%20examination%20according%20to%20the%20Diagnostic%20Criteria%20for%20Temporomandibular%20Disorders%20%28DC%5C%2FTMD%29%20was%20performed%20by%20trained%20dentists.%20Pubertal%20status%20according%20to%20Tanner%20stages%20was%20documented.%20Descriptive%20statistics%2C%20Mann-Whitney%20U%20and%20Wilcoxon%20signed-rank%20tests%20were%20performed.%5CnRESULTS%3A%20A%20total%20of%201.116%20participants%20%28mean%20age%2012.9%5Cu00a0years%2C%2051.4%25%20female%29%20were%20consecutively%20recruited.%20Most%20prevalent%20anamnestic%20symptoms%20were%20headaches%20%2855.7%25%29%20and%20temporomandibular%20joint%20%28TMJ%29%20sounds%20%2817.6%25%29.%20The%20major%20clinical%20sign%20was%20TMJ%20sounds%20%2831.9%25%29.%20Both%20the%20examination%20of%20muscles%20or%20TMJs%20showed%20that%20pain%20to%20palpation%20was%20statistically%20significantly%20higher%20than%20familiar%20pain%20%28P%5Cu00a0%3C%5Cu00a0.001%29.%20Gender%20comparisons%20revealed%20higher%20prevalence%20values%20and%20an%20increase%20in%20TMD%20symptoms%20and%20signs%20during%20pubertal%20development%20in%20females.%5CnCONCLUSION%3A%20The%20prevalence%20of%20self-reported%20headaches%2C%20as%20well%20as%20anamnestic%20and%20clinical%20TMJ%20sounds%2C%20was%20high%20in%20German%20adolescents.%20Prevalence%20values%20for%20pain%20to%20palpation%20and%20familiar%20pain%20obtained%20relevant%20differences.%20Considering%20the%20DC%5C%2FTMD%2C%20females%20are%20more%20affected%20by%20TMD%20signs%20and%20symptoms%20that%20increase%20during%20pubertal%20development%2C%20than%20male%20adolescents.%22%2C%22date%22%3A%22Apr%202020%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1111%5C%2Fjoor.12926%22%2C%22ISSN%22%3A%221365-2842%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fjoor.12926%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-07T07%3A01%3A30Z%22%7D%7D%2C%7B%22key%22%3A%22YRP88X4P%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Graf%20et%20al.%22%2C%22parsedDate%22%3A%222019-11%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EGraf%2C%20Caroline%2C%20Oliver%20Schierz%2C%20Hanno%20Steinke%2C%20Antje%20K%26%23xF6%3Brner%2C%20Wieland%20Kiess%2C%20J%26%23xFC%3Brgen%20Kratzsch%2C%20Christian%20Hirsch%2C%20and%20Life%20Child%20Study%20Team.%20%26%23x201C%3BSex%20Hormones%20in%20Association%20with%20General%20Joint%20Laxity%20and%20Hypermobility%20in%20the%20Temporomandibular%20Joint%20in%20Adolescents-Results%20of%20the%20Epidemiologic%20Life%20Child%20Study.%26%23x201D%3B%20%3Ci%3EJournal%20of%20Oral%20Rehabilitation%3C%5C%2Fi%3E%2046%2C%20no.%2011%20%28November%202019%29%3A%201023%26%23×2013%3B30.%20https%3A%5C%2F%5C%2Fdoi.org%5C%2F%3Ca%20class%3D%27zp-ItemURL%27%20target%3D%27_blank%27%20href%3D%2710.1111%5C%2Fjoor.12834%27%3E10.1111%5C%2Fjoor.12834%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Sex%20Hormones%20in%20Association%20with%20General%20Joint%20Laxity%20and%20Hypermobility%20in%20the%20Temporomandibular%20Joint%20in%20Adolescents-Results%20of%20the%20Epidemiologic%20Life%20Child%20Study%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Caroline%22%2C%22lastName%22%3A%22Graf%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Oliver%22%2C%22lastName%22%3A%22Schierz%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Hanno%22%2C%22lastName%22%3A%22Steinke%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J%5Cu00fcrgen%22%2C%22lastName%22%3A%22Kratzsch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christian%22%2C%22lastName%22%3A%22Hirsch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22name%22%3A%22Life%20Child%20Study%20Team%22%7D%5D%2C%22abstractNote%22%3A%22OBJECTIVES%3A%20The%20aim%20of%20this%20cross-sectional%20study%20was%20to%20investigate%20whether%20sex%20hormones%20%28testosterone%2C%20oestradiol%2C%20sex-hormone-binding%20globulin%5Cu00a0%3D%5Cu00a0SHBG%29%20are%20associated%20with%20general%20joint%20laxity%20%28GJL%29%20and%20hypermobility%20or%20derangements%20of%20the%20temporomandibular%20joint%20%28TMJ%29%20in%20adolescents.%5CnMETHODS%3A%20Within%20the%20LIFE%20Child%20study%2C%20970%20adolescents%20%2810-18%5Cu00a0years%29%20were%20included.%20GJL%20was%20assessed%20using%20the%20Beighton%20test.%20Maximum%20mouth%20opening%20%28MMO%29%20and%20clinical%20clicking%20sounds%20as%20signs%20of%20disc%20displacement%20%28DD%29%20in%20the%20TMJ%20were%20assessed%20according%20to%20the%20Diagnostic%20Criteria%20for%20Temporomandibular%20Disorders%20%28DC%5C%2FTMD%29.%20Serum%20levels%20of%20sex%20hormones%20were%20assessed%20using%20standardised%20laboratory%20analyses.%5CnRESULTS%3A%20Hypermobile%20joints%20were%20found%20in%2054.9%25%20%28N%5Cu00a0%3D%5Cu00a0532%29%20of%20the%20sample%3B%20females%20were%20more%20affected%20than%20males%20%2861.4%25%20vs.%2051.8%25%2C%20P%5Cu00a0%3C%5Cu00a00.001%29.%20Using%20logistic%20regression%20analyses%2C%20the%20odds%20ratio%20%28OR%29%20for%20having%20%3E1%20hypermobile%20joints%20increased%20to%201.15%20%2895%25%20confidence%20interval%20%5BCI%5D%3A%201.04-1.27%29%20in%20males%20and%201.09%20%2895%25%20CI%3A%201.02-1.17%29%20in%20females%20per%2010%20units%20of%20the%20SHBG%20serum%20level%2C%20compared%20to%20those%20without%20hypermobile%20joints-after%20controlling%20for%20the%20effect%20of%20age%2C%20adjusted%20BMI%2C%20pubertal%20development%20%28Tanner%20scale%29%2C%20testosterone%20as%20well%20as%20oestradiol%20levels.%20Female%20subjects%20with%20%3E1%20hypermobile%20joints%20showed%20a%20higher%20OR%20%281.89%3B%2095%25%20CI%3A%201.05-3.43%29%20for%20having%20clinical%20clicking%20sounds%20in%20the%20TMJ%20and%20a%203.28%20times%20higher%20OR%20%2895%25%20CI%3A%201.44-7.44%29%20for%20MMO%5Cu00a0%5Cu2265%5Cu00a055%5Cu00a0mm.%5CnCONCLUSIONS%3A%20We%20observed%20age-%20and%20gender-independent%20associations%20of%20higher%20SHBG%20serum%20levels%20with%20GJL%20in%20adolescents.%20Moreover%2C%20hypermobile%20female%20adolescents%20show%20a%20more%20frequent%20hypermobility%20of%20the%20TMJ%20and%20clinical%20signs%20of%20DD.%22%2C%22date%22%3A%22Nov%202019%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1111%5C%2Fjoor.12834%22%2C%22ISSN%22%3A%221365-2842%22%2C%22url%22%3A%2210.1111%5C%2Fjoor.12834%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-24T08%3A24%3A10Z%22%7D%7D%2C%7B%22key%22%3A%22RY5VI9KJ%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Elger%20et%20al.%22%2C%22parsedDate%22%3A%222019-05%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EElger%2C%20Wieland%2C%20Wieland%20Kiess%2C%20Antje%20K%26%23xF6%3Brner%2C%20Annett%20Schrock%2C%20Mandy%20Vogel%2C%20and%20Christian%20Hirsch.%20%26%23x201C%3BInfluence%20of%20Overweight%5C%2FObesity%2C%20Socioeconomic%20Status%2C%20and%20Oral%20Hygiene%20on%20Caries%20in%20Primary%20Dentition.%26%23x201D%3B%20%3Ci%3EJournal%20of%20Investigative%20and%20Clinical%20Dentistry%3C%5C%2Fi%3E%2010%2C%20no.%202%20%28May%202019%29%3A%20e12394.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fjicd.12394%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fjicd.12394%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Influence%20of%20Overweight%5C%2FObesity%2C%20Socioeconomic%20Status%2C%20and%20Oral%20Hygiene%20on%20Caries%20in%20Primary%20Dentition%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Elger%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Annett%22%2C%22lastName%22%3A%22Schrock%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christian%22%2C%22lastName%22%3A%22Hirsch%22%7D%5D%2C%22abstractNote%22%3A%22AIM%3A%20The%20aim%20of%20the%20present%20study%20was%20to%20investigate%20possible%20influences%20of%20overweight%20%28OW%29%5C%2Fobesity%20on%20caries%20in%20primary%20dentition.%20Socioeconomic%20status%20%28SES%29%20and%20quality%20of%20oral%20hygiene%20were%20also%20considered.%5CnMETHODS%3A%20In%20the%20present%20study%2C%201628%20children%20between%20the%20ages%20of%206%5Cu00a0months%20and%209%5Cu00a0years%20were%20included.%20In%20addition%20to%20dental%20examinations%20regarding%20the%20decayed%2C%20missing%2C%20filled%20teeth%20%28dmft%29%20index%20in%20primary%20dentition%20and%20the%20evaluation%20of%20oral%20hygiene%2C%20the%20body%20mass%20index%20standard%20deviation%20score%20%28BMI%20SDS%29%20was%20determined%2C%20and%20SES%20was%20recorded.%5CnRESULTS%3A%20The%20presence%20of%20OW%5C%2Fobesity%20was%20associated%20with%20higher%20caries%20prevalence%20%28P%5Cu00a0%3C%5Cu00a00.001%29.%20A%20lower%20SES%20and%20non-optimal%20oral%20hygiene%20were%20also%20associated%20with%20increased%20dmft.%20The%20Poisson%20regression%20also%20showed%20a%20significantly%20higher%20risk%20in%20the%20combination%20of%20a%20high%20SES%20and%20OW%5C%2Fobesity%20%28%5Cu03b2low-high%20%5Cu00a0%3D%5Cu00a00.21%2C%20P%5Cu00a0%3D%5Cu00a00.01%29.%20The%20increase%20was%20evident%20in%20both%20good%20and%20poor%20oral%20hygiene.%20In%20contrast%2C%20there%20was%20no%20difference%20between%20the%20lower%20and%20middle%20social%20strata%20%28%5Cu03b2low-medium%20%5Cu00a0%3D%5Cu00a00.03%2C%20P%5Cu00a0%3D%5Cu00a00.6%29.%20With%20increasing%20age%2C%20the%20BMI%20influence%20decreased%20%28%5Cu03b2age%3ABMISDS%20%5Cu00a0%3D%5Cu00a0-0.06%2C%20P%5Cu00a0%3C%5Cu00a00.001%29.%5CnCONCLUSIONS%3A%20BMI%2C%20oral%20hygiene%2C%20and%20SES%20are%20important%20factors%20in%20caries%20prevalence.%20In%20the%20highest%20social%20class%2C%20however%2C%20increased%20body%20weight%20has%20an%20adverse%20effect%20regardless%20of%20oral%20hygiene.%22%2C%22date%22%3A%22May%202019%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1111%5C%2Fjicd.12394%22%2C%22ISSN%22%3A%222041-1626%22%2C%22url%22%3A%22http%3A%5C%2F%5C%2Forgid.org%5C%2F10.1111%5C%2Fjicd.12394%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-07T07%3A01%3A49Z%22%7D%7D%2C%7B%22key%22%3A%22YZSQCZ8M%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Schmidt%20et%20al.%22%2C%22parsedDate%22%3A%222019-04%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3ESchmidt%2C%20Jana%2C%20Pia%20Strecker%2C%20Markus%20Kreuz%2C%20Markus%20L%26%23xF6%3Bffler%2C%20Wieland%20Kiess%2C%20Christian%20Hirsch%2C%20Joachim%20Thiery%2C%20et%20al.%20%26%23x201C%3BStress-Related%20Hormones%20in%20Association%20with%20Periodontal%20Condition%20in%20Adolescents-Results%20of%20the%20Epidemiologic%20Life%20Child%20Study.%26%23x201D%3B%20%3Ci%3EClinical%20Oral%20Investigations%3C%5C%2Fi%3E%2023%2C%20no.%204%20%28April%202019%29%3A%201793%26%23×2013%3B1802.%20https%3A%5C%2F%5C%2Fdoi.org%5C%2F%3Ca%20class%3D%27zp-ItemURL%27%20target%3D%27_blank%27%20href%3D%2710.1007%5C%2Fs00784-018-2599-3%27%3E10.1007%5C%2Fs00784-018-2599-3%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Stress-Related%20Hormones%20in%20Association%20with%20Periodontal%20Condition%20in%20Adolescents-Results%20of%20the%20Epidemiologic%20Life%20Child%20Study%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jana%22%2C%22lastName%22%3A%22Schmidt%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Pia%22%2C%22lastName%22%3A%22Strecker%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Markus%22%2C%22lastName%22%3A%22Kreuz%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Markus%22%2C%22lastName%22%3A%22L%5Cu00f6ffler%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christian%22%2C%22lastName%22%3A%22Hirsch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Joachim%22%2C%22lastName%22%3A%22Thiery%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ronny%22%2C%22lastName%22%3A%22Baber%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Yoon%20Ju%22%2C%22lastName%22%3A%22Bae%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J%5Cu00fcrgen%22%2C%22lastName%22%3A%22Kratzsch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Rainer%22%2C%22lastName%22%3A%22Haak%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Dirk%22%2C%22lastName%22%3A%22Ziebolz%22%7D%5D%2C%22abstractNote%22%3A%22OBJECTIVES%3A%20The%20aim%20of%20this%20study%20was%20to%20investigate%20the%20associations%20between%20blood%20levels%20of%20stress-related%20hormones%20and%20early%20signs%20of%20periodontal%20disease%20in%20children%20and%20adolescents.%5CnMATERIALS%20AND%20METHODS%3A%20Within%20the%20LIFE%20%28Leipzig%20research%20center%20for%20civilization%20diseases%29%20Child%20study%2C%20498%20adolescents%20%2810%20to%2018%5Cu00a0years%29%20were%20included.%20Early%20signs%20of%20periodontal%20inflammation%20were%20measured%20by%20probing%20depth%20%28PD%29%20at%20six%20index%20teeth%20%2816%2C%2011%2C%2026%2C%2036%2C%2031%2C%2046%29.%20Blood%20levels%20of%20stress-related%20hormones%20%28cortisol%2C%20dehydroepiandosterone-sulfate%20%5BDHEA-S%5D%29%20and%2C%20additionally%20interleukine-6%20%28IL-6%29%20were%20measured.%20Socioeconomic%20status%2C%20oral%20hygiene%2C%20orthodontic%20appliances%2C%20and%20nutritional%20status%2C%20recorded%20by%20body-mass-index-standard-deviation-score%20%28BMI-SDS%29%2C%20were%20considered%20as%20confounding%20factors.%20Additionally%2C%20in%2098%20participants%2C%20an%20oral%20chairside%20active%20matrix%20metalloproteinase-8%20%28aMMP-8%29%20test%20was%20performed.%20Statistical%20tests%20are%20the%20Mann-Whitney%20U%20tests%2C%20chi-squared%20tests%20and%20multivariate%20logistic%20regression%20model.%5CnRESULTS%3A%20IL-6%2C%20BMI-SDS%20as%20well%20as%20positive%20aMMP-8%20test%20result%20were%20significantly%20associated%20with%20maximum%20PD%5Cu2009%3E%5Cu20093%5Cu00a0mm%20%28p%5Cu00a0%3C%5Cu20090.05%29.%20However%2C%20no%20statistically%20significant%20associations%20between%20stress-related%20hormones%20%28cortisol%20and%20DHEA-S%29%20and%20presence%20of%20maximum%20PD%20%3E%5Cu20093%5Cu00a0mm%20were%20found%20%28p%5Cu00a0%3E%5Cu20090.05%29.%20Higher%20DHEA-S%20and%20BMI%20were%20associated%20with%20positive%20aMMP-8%20result%2C%20even%20after%20adjusting%20for%20age%20and%20gender%20%28p%5Cu00a0%3D%5Cu20090.027%2C%20padj%5Cu00a0%3D%5Cu20090.026%29.%5CnCONCLUSION%3A%20The%20results%20reveal%20no%20associations%20between%20PD%20and%20stress-related%20hormones%20cortisol%20and%20DHEA-S.%20aMMP-8%20test%20result%20might%20be%20associated%20with%20DHEA-S%20level.%20Nutritional%20status%20seems%20to%20influence%20periodontal%20disease%20in%20adolescents.%5CnCLINICAL%20RELEVANCE%3A%20DHEA-S%20and%20BMI-SDS%20show%20associations%20with%20early%20signs%20of%20periodontal%20disease%20in%20adolescents%20aged%2010%20to%2018%5Cu00a0years.%20This%20association%20should%20be%20confirmed%20by%20the%20investigation%20of%20high-risk%20groups.%22%2C%22date%22%3A%22Apr%202019%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1007%5C%2Fs00784-018-2599-3%22%2C%22ISSN%22%3A%221436-3771%22%2C%22url%22%3A%2210.1007%5C%2Fs00784-018-2599-3%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-24T11%3A21%3A35Z%22%7D%7D%2C%7B%22key%22%3A%22NJ2DGVEG%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Schmidt%20et%20al.%22%2C%22parsedDate%22%3A%222018-01%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3ESchmidt%2C%20Jana%2C%20Ulrike%20Guder%2C%20Markus%20Kreuz%2C%20Markus%20L%26%23xF6%3Bffler%2C%20Wieland%20Kiess%2C%20Christian%20Hirsch%2C%20Dirk%20Ziebolz%2C%20and%20Rainer%20Haak.%20%26%23x201C%3BAmmp-8%20in%20Correlation%20to%20Caries%20and%20Periodontal%20Condition%20in%20Adolescents%26%23×2014%3BResults%20of%20the%20Epidemiologic%20Life%20Child%20Study.%26%23x201D%3B%20%3Ci%3EClinical%20Oral%20Investigations%3C%5C%2Fi%3E%2022%2C%20no.%201%20%28January%202018%29%3A%20449%26%23×2013%3B60.%20%3Ca%20class%3D%27zp-ItemURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs00784-017-2132-0%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs00784-017-2132-0%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Ammp-8%20in%20Correlation%20to%20Caries%20and%20Periodontal%20Condition%20in%20Adolescents%5Cu2014Results%20of%20the%20Epidemiologic%20Life%20Child%20Study%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jana%22%2C%22lastName%22%3A%22Schmidt%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ulrike%22%2C%22lastName%22%3A%22Guder%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Markus%22%2C%22lastName%22%3A%22Kreuz%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Markus%22%2C%22lastName%22%3A%22L%5Cu00f6ffler%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christian%22%2C%22lastName%22%3A%22Hirsch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Dirk%22%2C%22lastName%22%3A%22Ziebolz%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Rainer%22%2C%22lastName%22%3A%22Haak%22%7D%5D%2C%22abstractNote%22%3A%22ObjectivesThe%20suitability%20of%20a%20chairside%20aMMP-8%20test%20in%20determination%20of%20periodontal%20inflammation%20and%20caries%20in%20adolescents%20was%20assessed.%20Secondly%2C%20the%20influence%20of%20orthodontic%20treatment%20on%20aMMP-8%20test%20result%20was%20analyzed.Materials%20and%20methodsWithin%20the%20LIFE%20Child%20study%2C%20434%20adolescents%20%2810%20to%2018%20years%29%20were%20included.%20Clinical%20dental%20examinations%20comprised%20caries%20experience%20%28DMF%5C%2FT-Index%29%2C%20signs%20of%20periodontal%20inflammation%20%28probing%20pocket%20depth%2C%20PPD%3B%20community%20periodontal%20index%20of%20treatment%20needs%3B%20CPITN%29%20at%20six%20index%20teeth%20and%20oral%20hygiene%20%28OH%29.%20Information%20about%20orthodontic%20appliances%20%28OA%29%20and%20socioeconomic%20status%20%28SES%29%20were%20obtained%20by%20validated%20questionnaires.%20Test%5Cu2019s%20sensitivity%20and%20specificity%20to%20detect%20periodontal%20inflammation%20and%20carious%20lesions%20were%20evaluated.%20The%20influence%20of%20OA%20on%20the%20test%20result%20was%20analyzed%20%28multivariate%20model%29.ResultsNo%20associations%20between%20age%2C%20gender%2C%20SES%20or%20OH%2C%20and%20test%20outcome%20were%20found%20%28p%20%3E%200.05%29.%20Positive%20test%20results%20correlated%20to%20periodontal%20findings%20%28CPITN%2C%20mean%20PPD%3B%20p%20%3C%200.001%29.%20However%2C%20for%20the%20detection%20of%20%5Cu2265%201%20site%28s%29%20with%20PPD%20%5Cu2265%204%20mm%2C%20the%20test%5Cu2019s%20sensitivity%20and%20specificity%20were%20found%20to%20be%2061%20and%2069%25%2C%20respectively.%20Multivariate%20analysis%20revealed%20a%20higher%20probability%20for%20a%20positive%20test%20result%20in%20cases%20of%20fixed%20OA%20%28odds%20ratio%205.02%2C%2095%25%20confidence%20interval%201.90%5Cu201313.19%29.%20The%20test%20had%20no%20diagnostic%20value%20considering%20carious%20lesions.ConclusionsThe%20chairside%20aMMP-8%20test%20does%20not%20reliably%20identify%20adolescents%20with%20periodontal%20inflammation.%20Positive%20test%20results%20were%20more%20frequent%20in%20case%20of%20OA.Clinical%20relevanceThe%20chairside%20aMMP-8%20test%20is%20no%20appropriate%20tool%20to%20screen%20children%20and%20adolescents%20neither%20for%20periodontal%20inflammation%20nor%20for%20carious%20lesions.%22%2C%22date%22%3A%22January%2C%202018%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1007%5C%2Fs00784-017-2132-0%22%2C%22ISSN%22%3A%221436-3771%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs00784-017-2132-0%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-07T07%3A01%3A26Z%22%7D%7D%2C%7B%22key%22%3A%229YDGJMQ3%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Fabian%20et%20al.%22%2C%22parsedDate%22%3A%222018-01%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EFabian%2C%20Sara%2C%20Bianca%20Gelbrich%2C%20Andreas%20Hiemisch%2C%20Wieland%20Kiess%2C%20Christian%20Hirsch%2C%20and%20LIFE%20Child%20study%20team.%20%26%23x201C%3BImpact%20of%20Overbite%20and%20Overjet%20on%20Oral%20Health-Related%20Quality%20of%20Life%20of%20Children%20and%20Adolescents.%26%23x201D%3B%20%3Ci%3EJournal%20of%20Orofacial%20Orthopedics%20%3D%20Fortschritte%20Der%20Kieferorthopadie%3A%20Organ%5C%2FOfficial%20Journal%20Deutsche%20Gesellschaft%20Fur%20Kieferorthopadie%3C%5C%2Fi%3E%2079%2C%20no.%201%20%28January%202018%29%3A%2029%26%23×2013%3B38.%20https%3A%5C%2F%5C%2Fdoi.org%5C%2F%3Ca%20class%3D%27zp-ItemURL%27%20target%3D%27_blank%27%20href%3D%2710.1007%5C%2Fs00056-017-0114-0%27%3E10.1007%5C%2Fs00056-017-0114-0%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Impact%20of%20Overbite%20and%20Overjet%20on%20Oral%20Health-Related%20Quality%20of%20Life%20of%20Children%20and%20Adolescents%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Sara%22%2C%22lastName%22%3A%22Fabian%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Bianca%22%2C%22lastName%22%3A%22Gelbrich%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andreas%22%2C%22lastName%22%3A%22Hiemisch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christian%22%2C%22lastName%22%3A%22Hirsch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22name%22%3A%22LIFE%20Child%20study%20team%22%7D%5D%2C%22abstractNote%22%3A%22BACKGROUND%3A%20Usually%2C%20morphological%20parameters%20of%20the%20teeth%20are%20recorded%20to%20help%20assess%20the%20indication%20for%20orthodontic%20treatment.%20It%20is%20assumed%20that%20significant%20deviations%20from%20average%20values%20compromise%20the%20quality%20of%20life.%20The%20aim%20of%20this%20study%20is%20to%20analyse%20the%20impact%20of%20overbite%20and%20overjet%20on%20oral%20health-related%20quality%20of%20life%20%28OHRQoL%29%20of%20children%20and%20adolescents.%5CnPATIENTS%20AND%20METHODS%3A%20A%20total%20of%20748%20subjects%2C%20aged%209.5-15.5%20years%2C%20participated%20in%20the%20LIFE%20child%20project%20of%20the%20University%20of%20Leipzig%2C%20where%20they%20underwent%20a%5Cu00a0general%20medical%20and%20dental%20examination.%20Overbite%20and%20overjet%20were%20measured%2C%20and%20aberrations%20of%20the%20OHRQoL%20were%20recorded%20by%20the%20probands%20themselves%2C%20who%20completed%20the%20German%20version%20of%20the%20Child%20Perceptions%20Questionnaire%20%28CPQ-G11-14%29.%20The%20OHRQoL%20is%20divided%20into%20four%20domains%20%28%5C%22oral%20symptoms%5C%22%2C%20%5C%22functional%20limitations%5C%22%2C%20%5C%22emotional%20well-being%5C%22%20and%20%5C%22social%20well-being%5C%22%29%20and%20is%20analysed%20by%20means%20of%20a%5Cu00a0CPQ%20score%20depending%20on%20age%2C%20gender%2C%20socioeconomic%20status%20and%20orthodontic%20treatment.%5CnRESULTS%3A%20On%20average%2C%20the%20participants%20listed%2010.5%20%28%5Cu00b113.1%29%20problem%20issues%20on%20a%5Cu00a0CPQ%20scale%20ranging%20from%200%20to%20140.%20Subjects%20with%20current%20orthodontic%20treatment%20had%20a%5Cu00a0CPQ%20score%20about%202.5%20%28%5Cu00b12.4%29%20higher%20than%20those%20without%20treatment.%20The%20aberrations%20were%20mainly%20observed%20in%20the%20domains%20%5C%22oral%20symptoms%5C%22%20and%20%5C%22functional%20limitations%5C%22.%20Multiple%20linear%20regression%20showed%20that%20deviations%20of%20the%20overbite%20had%20only%20little%20influence%20on%20the%20OHRQoL%2C%20but%20deviations%20of%20an%20overjet-especially%20of%20%3E6%5Cu2009mm%20increased%20the%20CPQ%20summary%20score%20about%206%5Cu00a0points.%5CnCONCLUSION%3A%20Children%20and%20adolescents%20with%20overjet%20deviations%20of%20%3E6%5Cu2009mm%20in%20comparison%20to%20the%20norm%20are%20associated%20with%20significant%20limitations%20of%20the%20OHRQoL.%20However%2C%20overbite%20deviations%20have%20only%20little%20influence.%22%2C%22date%22%3A%22January%202018%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1007%5C%2Fs00056-017-0114-0%22%2C%22ISSN%22%3A%221615-6714%22%2C%22url%22%3A%2210.1007%5C%2Fs00056-017-0114-0%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-07T07%3A01%3A48Z%22%7D%7D%5D%7D
Hirsch, Christian, Oliver Schierz, Antje Körner, Wieland Kiess, Ronald Biemann, Annett Schrock, and Jens Christoph Türp. “Sex Hormones Associated with Temporomandibular Pain on Palpation in Male Adolescents—Results of the Epidemiologic LIFE Child Study.” Journal of Oral Rehabilitation n/a, no. n/a (2023). https://doi.org/10.1111/joor.13530.
Buchhardt, Jeanette, Wieland Kiess, Antje Körner, Ronald Biemann, Christian Hirsch, and Life Child Study Team. “The Influence of Steroid Hormones on Tooth Wear in Children and in Adolescents.” Journal of Clinical Medicine 11, no. 13 (June 22, 2022): 3603. https://doi.org/10.3390/jcm11133603.
Kolbow, Henrike, Wieland Kiess, Christian Hirsch, Mandy Vogel, Annett Schrock, and Wieland Elger. “The Influence of Coordinative Skills on the Oral Health of Children and Adolescents in Permanent Dentition.” Journal of Clinical Medicine 11, no. 21 (January 2022): 6472. https://doi.org/10.3390/jcm11216472.
Schmidt, Jana, Mandy Vogel, Tanja Poulain, Wieland Kiess, Christian Hirsch, Dirk Ziebolz, and Rainer Haak. “Association of Oral Health Conditions in Adolescents with Social Factors and Obesity.” International Journal of Environmental Research and Public Health 19, no. 5 (January 2022): 2905. https://doi.org/10.3390/ijerph19052905.
Rauch, Angelika, Antje Körner, Wieland Kiess, Christian Hirsch, and Oliver Schierz. “Relationship between Age-Dependent Body Constitution and Temporomandibular Joint Sounds in Adolescents.” Journal of Clinical Medicine 9, no. 11 (November 2020): 3927. https://doi.org/10.3390/jcm9123927.
Elger, Wieland, Christina Illge, Wieland Kiess, Antje Körner, Jürgen Kratzsch, Annett Schrock, and Christian Hirsch. “Relationship Between Deciduous Molar Hypomineralisation and Parameters of Bone Metabolism in Preschool Children.” International Dental Journal 70, no. 4 (August 2020): 303–7. https://doi.org/10.1111/idj.12550.
Rauch, Angelika, Oliver Schierz, Antje Körner, Wieland Kiess, and Christian Hirsch. “Prevalence of Anamnestic Symptoms and Clinical Signs of Temporomandibular Disorders in Adolescents-Results of the Epidemiologic Life Child Study.” Journal of Oral Rehabilitation 47, no. 4 (April 2020): 425–31. https://doi.org/10.1111/joor.12926.
Graf, Caroline, Oliver Schierz, Hanno Steinke, Antje Körner, Wieland Kiess, Jürgen Kratzsch, Christian Hirsch, and Life Child Study Team. “Sex Hormones in Association with General Joint Laxity and Hypermobility in the Temporomandibular Joint in Adolescents-Results of the Epidemiologic Life Child Study.” Journal of Oral Rehabilitation 46, no. 11 (November 2019): 1023–30. https://doi.org/10.1111/joor.12834.
Elger, Wieland, Wieland Kiess, Antje Körner, Annett Schrock, Mandy Vogel, and Christian Hirsch. “Influence of Overweight/Obesity, Socioeconomic Status, and Oral Hygiene on Caries in Primary Dentition.” Journal of Investigative and Clinical Dentistry 10, no. 2 (May 2019): e12394. https://doi.org/10.1111/jicd.12394.
Schmidt, Jana, Pia Strecker, Markus Kreuz, Markus Löffler, Wieland Kiess, Christian Hirsch, Joachim Thiery, et al. “Stress-Related Hormones in Association with Periodontal Condition in Adolescents-Results of the Epidemiologic Life Child Study.” Clinical Oral Investigations 23, no. 4 (April 2019): 1793–1802. https://doi.org/10.1007/s00784-018-2599-3.
Schmidt, Jana, Ulrike Guder, Markus Kreuz, Markus Löffler, Wieland Kiess, Christian Hirsch, Dirk Ziebolz, and Rainer Haak. “Ammp-8 in Correlation to Caries and Periodontal Condition in Adolescents—Results of the Epidemiologic Life Child Study.” Clinical Oral Investigations 22, no. 1 (January 2018): 449–60. https://doi.org/10.1007/s00784-017-2132-0.
Fabian, Sara, Bianca Gelbrich, Andreas Hiemisch, Wieland Kiess, Christian Hirsch, and LIFE Child study team. “Impact of Overbite and Overjet on Oral Health-Related Quality of Life of Children and Adolescents.” Journal of Orofacial Orthopedics = Fortschritte Der Kieferorthopadie: Organ/Official Journal Deutsche Gesellschaft Fur Kieferorthopadie 79, no. 1 (January 2018): 29–38. https://doi.org/10.1007/s00056-017-0114-0.
2390247
T52N9QLZ
anthro
1
chicago-fullnote-bibliography
50
date
desc
1
1
6748
https://home.uni-leipzig.de/lifechild/wp-content/plugins/zotpress/
%7B%22status%22%3A%22success%22%2C%22updateneeded%22%3Afalse%2C%22instance%22%3Afalse%2C%22meta%22%3A%7B%22request_last%22%3A0%2C%22request_next%22%3A0%2C%22used_cache%22%3Atrue%7D%2C%22data%22%3A%5B%7B%22key%22%3A%229QSQSGQJ%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Kabbani%20et%20al.%22%2C%22parsedDate%22%3A%222023-08-08%22%2C%22numChildren%22%3A3%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EKabbani%2C%20Noura%2C%20Holger%20Stepan%2C%20Matthias%20Bl%26%23xFC%3Bher%2C%20Thomas%20Ebert%2C%20Ronny%20Baber%2C%20Mandy%20Vogel%2C%20Wieland%20Kiess%2C%20et%20al.%20%26%23x201C%3BAssociation%20between%20TGF%26%23x3B2%3B1%20Levels%20in%20Cord%20Blood%20and%20Weight%20Progress%20in%20the%20First%20Year%20of%20Life.%26%23x201D%3B%20%3Ci%3EBiomedicines%3C%5C%2Fi%3E%2011%2C%20no.%208%20%28August%208%2C%202023%29%3A%202220.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Fbiomedicines11082220%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.3390%5C%2Fbiomedicines11082220%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Association%20between%20TGF%5Cu03b21%20Levels%20in%20Cord%20Blood%20and%20Weight%20Progress%20in%20the%20First%20Year%20of%20Life%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Noura%22%2C%22lastName%22%3A%22Kabbani%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Holger%22%2C%22lastName%22%3A%22Stepan%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Matthias%22%2C%22lastName%22%3A%22Bl%5Cu00fcher%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Thomas%22%2C%22lastName%22%3A%22Ebert%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ronny%22%2C%22lastName%22%3A%22Baber%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Michael%22%2C%22lastName%22%3A%22Stumvoll%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jana%22%2C%22lastName%22%3A%22Breitfeld%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ulrike%22%2C%22lastName%22%3A%22L%5Cu00f6ssner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anke%22%2C%22lastName%22%3A%22T%5Cu00f6njes%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Susanne%22%2C%22lastName%22%3A%22Schrey-Petersen%22%7D%5D%2C%22abstractNote%22%3A%22Transforming%20growth%20factor%20beta-1%20%28TGF%5Cu03b21%29%20is%20an%20adipokine%20secreted%20from%20adipose%20tissue%2C%20placental%20tissue%20and%20immune%20cells%20with%20a%20role%20in%20cell%20proliferation%2C%20cell%20apoptosis%20and%20angiogenic%20proliferation.%20The%20role%20of%20TGF%5Cu03b21%20in%20pregnancy%20and%20child%20growth%20and%20the%20source%20of%20cord%20TGF%5Cu03b21%20are%20yet%20unknown.%20In%20this%20study%2C%20we%20sought%20to%20clarify%20the%20correlation%20of%20TGF%5Cu03b21%20levels%20with%20parameters%20of%20intrauterine%20growth%20and%20child%20growth%20during%20the%20first%20year%20of%20life%2C%20and%20to%20determine%20whether%20their%20source%20is%20primarily%20of%20fetal%20or%20maternal%20origin.%20Serum%20samples%20and%20anthropometric%20measurements%20were%20obtained%20from%20the%20LIFE%20Child%20cohort%20of%2079%20healthy%20mother-child%20pairs.%20Measurements%20were%20conducted%20using%20enzyme-linked%20immunosorbent%20assays.%20Statistical%20analyses%20including%20Mann-Whitney%20U-test%2C%20correlation%20analyses%20and%20linear%20regression%20analyses%20were%20performed%20using%20GraphPad%20Prism%20and%20R.%20TGF%5Cu03b21%20levels%20were%20significantly%20higher%20in%20cord%20than%20in%20maternal%20serum%2C%20suggesting%20a%20fetal%20origin.%20Multivariate%20regression%20analyses%20revealed%20strong%20positive%20associations%20between%20cord%20TGF%5Cu03b21%20levels%20at%20birth%20and%20child%20weight%20at%20U6.%20Furthermore%2C%20cord%20TGF%5Cu03b21%20was%20significantly%20correlated%20with%20child%20weight%20at%20approximately%20one%20year%20of%20age.%20An%20increase%20of%2010%2C000%20pg%5C%2FmL%20in%20cord%20TGF%5Cu03b21%20concentrations%20at%20birth%20was%20associated%20with%20a%20higher%20body%20weight%20of%20201%20g%20at%20roughly%20one%20year%20of%20age%20when%20adjusted%20for%20sex.%22%2C%22date%22%3A%222023-08-08%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.3390%5C%2Fbiomedicines11082220%22%2C%22ISSN%22%3A%222227-9059%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222024-08-27T13%3A09%3A35Z%22%7D%7D%2C%7B%22key%22%3A%22SRQN35UR%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Pf%5Cu00e4ffle%20et%20al.%22%2C%22parsedDate%22%3A%222022-11-25%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EPf%26%23xE4%3Bffle%2C%20Roland%2C%20Matthias%20Kn%26%23xFC%3Bpfer%2C%20Melanie%20G%26%23xF6%3Bbert%2C%20Mandy%20Vogel%2C%20Ruth%20Gausche%2C%20Christoph%20Beger%2C%20Eberhard%20Keller%2C%20Antje%20K%26%23xF6%3Brner%2C%20Ulrich%20Thome%2C%20and%20Wieland%20Kiess.%20%26%23x201C%3BGrowth%20Patterns%20of%20Children%20With%20Short%20Stature%20in%20Adulthood%20According%20to%20Auxological%20Status%20and%20Maturity%20at%20Birth.%26%23x201D%3B%20%3Ci%3EThe%20Journal%20of%20Clinical%20Endocrinology%20and%20Metabolism%3C%5C%2Fi%3E%20107%2C%20no.%2012%20%28November%2025%2C%202022%29%3A%203320%26%23×2013%3B27.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F2022112511292049000%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F2022112511292049000%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Growth%20Patterns%20of%20Children%20With%20Short%20Stature%20in%20Adulthood%20According%20to%20Auxological%20Status%20and%20Maturity%20at%20Birth%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Roland%22%2C%22lastName%22%3A%22Pf%5Cu00e4ffle%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Matthias%22%2C%22lastName%22%3A%22Kn%5Cu00fcpfer%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Melanie%22%2C%22lastName%22%3A%22G%5Cu00f6bert%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ruth%22%2C%22lastName%22%3A%22Gausche%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christoph%22%2C%22lastName%22%3A%22Beger%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Eberhard%22%2C%22lastName%22%3A%22Keller%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ulrich%22%2C%22lastName%22%3A%22Thome%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%5D%2C%22abstractNote%22%3A%22CONTEXT%3A%20Prematurity%20carries%20a%20risk%20for%20impaired%20postnatal%20growth%20and%20long-term%20growth%20restriction.%20Especially%20children%20born%20SGA%20seem%20vulnerable%20for%20poor%20growth%2C%20as%20a%20persistent%20short%20stature%20can%20be%20observed%20in%20app%2010-15%25%20of%20these%20children.%5CnOBJECTIVE%3A%20In%20this%20study%20we%20aimed%20to%20recognize%20differences%20in%20growth%20patterns%20of%20children%20according%20to%20sex%2C%20maturity%2C%20and%20auxological%20status%20at%20birth%20facilitating%20earlier%20identification%20of%20small-for-gestational-age%20%28SGA%29%20children%20with%20adult%20short%20stature.%5CnMETHODS%3A%20The%20growth%20data%20of%2044%5Cu2005791%20infants%20born%20between%20January%201%2C%201980%2C%20and%20December%2030%2C%202012%2C%20among%202%20pediatric%20cohorts%20with%20follow-up%20through%20December%2031%2C%202020%2C%20were%20analyzed.%20A%20total%20of%205698%20children%20with%20birth%20data%20had%20measurements%20at%20near%20final%20height%20%28nfh%29%20and%20at%20least%202%20further%20points.%5CnRESULTS%3A%20Preterm%20children%20%28gestational%20age%20%3C%5Cu200537%20weeks%29%20had%20a%20significantly%20lower%20mean%20nfh%20SDS%20than%20term%20children%20%28preterm%2C%20-0.61%3B%20term%2C%20-0.18%29%20and%20a%20higher%20likelihood%20of%20nfh%20%3C%5Cu2005third%20percentile%20%28preterm%2C%2020.5%25%3B%20term%2C%2012.2%25%29.%20SGA%20born%20children%20also%20had%20a%20lower%20mean%20nfh%20SD%20score%20%28SDS%29%20than%20children%20born%20appropriate%20for%20gestational%20age%20%28AGA%29%20%28SGA%2C%20-1.06%3B%20AGA%2C%20-0.15%29%20and%20a%20higher%20likelihood%20of%20nfh%20%3C%5Cu2005third%20percentile%20%28SGA%2C%2028.2%25%3B%20AGA%2010.1%25%29.%20Of%201204%20SGA%20children%2C%20672%20%2856%25%29%20showed%20successful%20catch-up%20growth%20%28CUG%29%20to%20nfh%20greater%20than%20or%20equal%20to%20the%2010th%20percentile%20%28SGA-CU%29%2C%20and%20532%20children%20%2844%25%29%20did%20not%20%28SGA-S%29.%20The%20difference%20in%20their%20mean%20nfh%20SDS%20%28SGA-CU%2C%20-0.12%3B%20SGA-S%20-2.26%29%20can%20only%20partly%20be%20explained%20by%20the%20differences%20in%20mean%20mid-parental%20height%20SDS%20%28SGA-CU%2C%20-0.3%3B%20SGA-S%2C%20-1.19%29.%20During%20the%20first%20year%2C%20SGA-CU%20showed%20higher%20CUG%20%28SGA-CU%2C%20%2B1.2%20SDS%3B%20SGA-S%2C%20%2B0.45%20SDS%29%2C%20which%20helps%20to%20discriminate%20between%20groups%20earlier.%5CnCONCLUSION%3A%20Final%20growth%20outcome%20was%20influenced%20by%20prematurity%20and%20auxological%20status%20at%20birth%2C%20but%20not%20by%20sex.%20Height%5C%2Flength%20SDS%20increments%20during%20year%201%20are%20instrumental%20to%20discern%20SGA%20children%20with%20later%20normal%20or%20short%20stature.%20While%20observing%20CUG%20until%20year%202%20and%203%20can%20add%20specificity%2C%20discrimination%20thereafter%20becomes%20difficult.%22%2C%22date%22%3A%222022-11-25%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%222022112511292049000%22%2C%22ISSN%22%3A%221945-7197%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222024-08-27T13%3A13%3A14Z%22%7D%7D%2C%7B%22key%22%3A%22HT7DRXIX%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Vogelezang%20et%20al.%22%2C%22parsedDate%22%3A%222022-06-04%22%2C%22numChildren%22%3A2%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EVogelezang%2C%20Suzanne%2C%20Jonathan%20P.%20Bradfield%2C%20Early%20Growth%20Genetics%20Consortium%2C%20Struan%20F.%20A.%20Grant%2C%20Janine%20F.%20Felix%2C%20and%20Vincent%20W.%20V.%20Jaddoe.%20%26%23x201C%3BGenetics%20of%20Early-Life%20Head%20Circumference%20and%20Genetic%20Correlations%20with%20Neurological%2C%20Psychiatric%20and%20Cognitive%20Outcomes.%26%23x201D%3B%20%3Ci%3EBMC%20Medical%20Genomics%3C%5C%2Fi%3E%2015%2C%20no.%201%20%28June%204%2C%202022%29%3A%20124.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs12920-022-01281-1%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs12920-022-01281-1%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Genetics%20of%20early-life%20head%20circumference%20and%20genetic%20correlations%20with%20neurological%2C%20psychiatric%20and%20cognitive%20outcomes%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Suzanne%22%2C%22lastName%22%3A%22Vogelezang%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jonathan%20P.%22%2C%22lastName%22%3A%22Bradfield%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22name%22%3A%22Early%20Growth%20Genetics%20Consortium%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Struan%20F.%20A.%22%2C%22lastName%22%3A%22Grant%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Janine%20F.%22%2C%22lastName%22%3A%22Felix%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Vincent%20W.%20V.%22%2C%22lastName%22%3A%22Jaddoe%22%7D%5D%2C%22abstractNote%22%3A%22BACKGROUND%3A%20Head%20circumference%20is%20associated%20with%20intelligence%20and%20tracks%20from%20childhood%20into%20adulthood.%5CnMETHODS%3A%20We%20performed%20a%20genome-wide%20association%20study%20meta-analysis%20and%20follow-up%20of%20head%20circumference%20in%20a%20total%20of%2029%2C192%20participants%20between%206%20and%2030%5Cu00a0months%20of%20age.%5CnRESULTS%3A%20Seven%20loci%20reached%20genome-wide%20significance%20in%20the%20combined%20discovery%20and%20replication%20analysis%20of%20which%20three%20loci%20near%20ARFGEF2%2C%20MYCL1%2C%20and%20TOP1%2C%20were%20novel.%20We%20observed%20positive%20genetic%20correlations%20for%20early-life%20head%20circumference%20with%20adult%20intracranial%20volume%2C%20years%20of%20schooling%2C%20childhood%20and%20adult%20intelligence%2C%20but%20not%20with%20adult%20psychiatric%2C%20neurological%2C%20or%20personality-related%20phenotypes.%5CnCONCLUSIONS%3A%20The%20results%20of%20this%20study%20indicate%20that%20the%20biological%20processes%20underlying%20early-life%20head%20circumference%20overlap%20largely%20with%20those%20of%20adult%20head%20circumference.%20The%20associations%20of%20early-life%20head%20circumference%20with%20cognitive%20outcomes%20across%20the%20life%20course%20are%20partly%20explained%20by%20genetics.%22%2C%22date%22%3A%222022-06-04%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1186%5C%2Fs12920-022-01281-1%22%2C%22ISSN%22%3A%221755-8794%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222024-08-27T13%3A14%3A55Z%22%7D%7D%2C%7B%22key%22%3A%22L77AIQZE%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22R%5Cu00f6nnecke%20et%20al.%22%2C%22parsedDate%22%3A%222019-03%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3ER%26%23xF6%3Bnnecke%2C%20Elisa%2C%20Mandy%20Vogel%2C%20Sarah%20Bussler%2C%20Nico%20Grafe%2C%20Anne%20Jurkutat%2C%20Maike%20Schlingmann%2C%20Antje%20Koerner%2C%20and%20Wieland%20Kiess.%20%26%23x201C%3BAge-%20and%20Sex-Related%20Percentiles%20of%20Skinfold%20Thickness%2C%20Waist%20and%20Hip%20Circumference%2C%20Waist-to-Hip%20Ratio%20and%20Waist-to-Height%20Ratio%3A%20Results%20from%20a%20Population-Based%20Pediatric%20Cohort%20in%20Germany%20%28LIFE%20Child%29.%26%23x201D%3B%20%3Ci%3EObesity%20Facts%3C%5C%2Fi%3E%2012%2C%20no.%201%20%28March%202019%29%3A%2025%26%23×2013%3B39.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1159%5C%2F000494767%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1159%5C%2F000494767%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Age-%20and%20Sex-Related%20Percentiles%20of%20Skinfold%20Thickness%2C%20Waist%20and%20Hip%20Circumference%2C%20Waist-to-Hip%20Ratio%20and%20Waist-to-Height%20Ratio%3A%20Results%20from%20a%20Population-Based%20Pediatric%20Cohort%20in%20Germany%20%28LIFE%20Child%29%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Elisa%22%2C%22lastName%22%3A%22R%5Cu00f6nnecke%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Sarah%22%2C%22lastName%22%3A%22Bussler%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Nico%22%2C%22lastName%22%3A%22Grafe%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anne%22%2C%22lastName%22%3A%22Jurkutat%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Maike%22%2C%22lastName%22%3A%22Schlingmann%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22Koerner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%5D%2C%22abstractNote%22%3A%22BACKGROUND%3A%20Skinfold%20thickness%20%28ST%29%2C%20waist%20circumference%20%28WC%29%20and%20hip%20circumference%20%28HC%29%20measurements%20are%20simple%20methods%20for%20assessing%20fat%20tissue%20at%20defined%20body%20parts.%20We%20examined%20these%20parameters%20in%20a%20cohort%20of%20healthy%20children%20and%20adolescents%20in%20Leipzig.%20Our%20study%20provides%20current%20percentile%20curves%20for%20biceps%2C%20triceps%2C%20subscapular%20and%20iliac%20crest%20ST%2C%20plus%20WC%2C%20HC%2C%20waist-to-hip%20ratio%20and%20waist-to-height%20ratio.%5CnMETHODS%3A%206%2C344%20visits%20were%20recorded%20involving%202%2C363%20individuals%20from%203%20to%2016%20years%20in%20age.%20Continuous%20age-%20and%20gender-related%20percentiles%20%283rd%2C%2010th%2C%20median%2C%2090th%2C%2097th%20percentiles%29%20were%20estimated%20using%20Cole%27s%20LMS%20method.%5CnRESULTS%3A%20For%20biceps%20and%20triceps%20ST%2C%20boys%20show%20a%20peak%20at%20the%20beginning%20of%20adolescence%20with%20a%20subsequent%20decrease%2C%20while%20percentile%20values%20among%20girls%20rise%20across%20the%20age%20range.%20Subscapular%20and%20iliac%20crest%20percentiles%20also%20show%20increasing%20curves%20with%20disproportionately%20high%20values%20for%20P90%20and%20P97.%20Boys%20show%20higher%20values%20of%20WC%2C%20girls%20have%20higher%20levels%20of%20HC.%20WC%20and%20HC%20median%20percentiles%20constantly%20increase%20in%20both%20sexes%20with%20a%20plateau%20at%20the%20age%20of%2016%20for%20girls.%5CnCONCLUSION%3A%20Trends%20for%20all%20parameters%20of%20body%20fat%20are%20in%20line%20with%20other%20national%20and%20international%20studies.%20Unlike%20the%20KiGGS%20study%2C%20our%20study%20provides%20circumference%20data%20across%20the%20whole%20of%20our%20age%20range%2C%20i.e.%20from%203%20to%2016%20years.%22%2C%22date%22%3A%22March%202019%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1159%5C%2F000494767%22%2C%22ISSN%22%3A%221662-4033%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222024-01-02T15%3A22%3A54Z%22%7D%7D%2C%7B%22key%22%3A%22SFPARI6Q%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Loeffler-Wirth%20et%20al.%22%2C%22parsedDate%22%3A%222018-09%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3ELoeffler-Wirth%2C%20Henry%2C%20Mandy%20Vogel%2C%20Toralf%20Kirsten%2C%20Fabian%20Glock%2C%20Tanja%20Poulain%2C%20Antje%20K%26%23xF6%3Brner%2C%20Markus%20Loeffler%2C%20Wieland%20Kiess%2C%20and%20Hans%20Binder.%20%26%23x201C%3BLongitudinal%20Anthropometry%20of%20Children%20and%20Adolescents%20Using%203d-Body%20Scanning.%26%23x201D%3B%20%3Ci%3EPloS%20One%3C%5C%2Fi%3E%2013%2C%20no.%209%20%28September%202018%29%3A%20e0203628.%20https%3A%5C%2F%5C%2Fdoi.org%5C%2F%3Ca%20class%3D%27zp-ItemURL%27%20target%3D%27_blank%27%20href%3D%2710.1371%5C%2Fjournal.pone.0203628%27%3E10.1371%5C%2Fjournal.pone.0203628%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Longitudinal%20Anthropometry%20of%20Children%20and%20Adolescents%20Using%203d-Body%20Scanning%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Henry%22%2C%22lastName%22%3A%22Loeffler-Wirth%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Toralf%22%2C%22lastName%22%3A%22Kirsten%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Fabian%22%2C%22lastName%22%3A%22Glock%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Markus%22%2C%22lastName%22%3A%22Loeffler%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Hans%22%2C%22lastName%22%3A%22Binder%22%7D%5D%2C%22abstractNote%22%3A%223D-body%20scanning%20anthropometry%20is%20a%20suitable%20method%20for%20characterization%20of%20physiological%20development%20of%20children%20and%20adolescents%2C%20and%20for%20understanding%20onset%20and%20progression%20of%20disorders%20like%20overweight%20and%20obesity.%20Here%20we%20present%20a%20novel%20body%20typing%20approach%20to%20describe%20and%20to%20interpret%20longitudinal%203D-body%20scanning%20data%20of%20more%20than%20800%20children%20and%20adolescents%20measured%20in%20up%20to%20four%20follow-ups%20in%20intervals%20of%201%20year%2C%20referring%20to%20an%20age%20range%20between%206%20and%2018%20years.%20We%20analyzed%20transitions%20between%20body%20types%20assigned%20to%20lower-%2C%20normal-%20and%20overweight%20participants%20upon%20development%20of%20children%20and%20adolescents.%20We%20found%20a%20virtually%20parallel%20development%20of%20the%20body%20types%20with%20only%20a%20few%20transitions%20between%20them.%20Body%20types%20of%20children%20and%20adolescents%20tend%20to%20conserve%20their%20weight%20category.%203D%20body%20scanning%20anthropometry%20in%20combination%20with%20body%20typing%20constitutes%20a%20novel%20option%20to%20investigate%20onset%20and%20progression%20of%20obesity%20in%20children.%22%2C%22date%22%3A%222018-09%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1371%5C%2Fjournal.pone.0203628%22%2C%22ISSN%22%3A%221932-6203%22%2C%22url%22%3A%2210.1371%5C%2Fjournal.pone.0203628%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-07T07%3A01%3A39Z%22%7D%7D%2C%7B%22key%22%3A%22IJI97JMV%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Loeffler-Wirth%20et%20al.%22%2C%22parsedDate%22%3A%222017-10%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3ELoeffler-Wirth%2C%20Henry%2C%20Mandy%20Vogel%2C%20Toralf%20Kirsten%2C%20Fabian%20Glock%2C%20Tanja%20Poulain%2C%20Antje%20K%26%23xF6%3Brner%2C%20Markus%20Loeffler%2C%20Wieland%20Kiess%2C%20and%20Hans%20Binder.%20%26%23x201C%3BBody%20Typing%20of%20Children%20and%20Adolescents%20Using%203d-Body%20Scanning.%26%23x201D%3B%20%3Ci%3EPloS%20One%3C%5C%2Fi%3E%2012%2C%20no.%2010%20%28October%202017%29%3A%20e0186881.%20https%3A%5C%2F%5C%2Fdoi.org%5C%2F%3Ca%20class%3D%27zp-ItemURL%27%20target%3D%27_blank%27%20href%3D%2710.1371%5C%2Fjournal.pone.0186881%27%3E10.1371%5C%2Fjournal.pone.0186881%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Body%20Typing%20of%20Children%20and%20Adolescents%20Using%203d-Body%20Scanning%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Henry%22%2C%22lastName%22%3A%22Loeffler-Wirth%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Toralf%22%2C%22lastName%22%3A%22Kirsten%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Fabian%22%2C%22lastName%22%3A%22Glock%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Markus%22%2C%22lastName%22%3A%22Loeffler%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Hans%22%2C%22lastName%22%3A%22Binder%22%7D%5D%2C%22abstractNote%22%3A%22Three-dimensional%20%283D-%29%20body%20scanning%20of%20children%20and%20adolescents%20allows%20the%20detailed%20study%20of%20physiological%20development%20in%20terms%20of%20anthropometrical%20alterations%20which%20potentially%20provide%20early%20onset%20markers%20for%20obesity.%20Here%2C%20we%20present%20a%20systematic%20analysis%20of%20body%20scanning%20data%20of%202%2C700%20urban%20children%20and%20adolescents%20in%20the%20age%20range%20between%205%20and%2018%20years%20with%20the%20special%20aim%20to%20stratify%20the%20participants%20into%20distinct%20body%20shape%20types%20and%20to%20describe%20their%20change%20upon%20development.%20In%20a%20first%20step%2C%20we%20extracted%20a%20set%20of%20eight%20representative%20meta-measures%20from%20the%20data.%20Each%20of%20them%20collects%20a%20related%20group%20of%20anthropometrical%20features%20and%20changes%20specifically%20upon%20aging.%20In%20a%20second%20step%20we%20defined%20seven%20body%20types%20by%20clustering%20the%20meta-measures%20of%20all%20participants.%20These%20body%20types%20describe%20the%20body%20shapes%20in%20terms%20of%20three%20weight%20%28lower%2C%20normal%20and%20overweight%29%20and%20three%20age%20%28young%2C%20medium%20and%20older%29%20categories.%20For%20younger%20children%20%28age%20of%205-10%20years%29%20we%20found%20a%20common%20%27early%20childhood%20body%20shape%27%20which%20splits%20into%20three%20weight-dependent%20types%20for%20older%20children%2C%20with%20one%20or%20two%20years%20delay%20for%20boys.%20Our%20study%20shows%20that%20the%20concept%20of%20body%20types%20provides%20a%20reliable%20option%20for%20the%20anthropometric%20characterization%20of%20developing%20and%20aging%20populations.%22%2C%22date%22%3A%222017-10%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1371%5C%2Fjournal.pone.0186881%22%2C%22ISSN%22%3A%221932-6203%22%2C%22url%22%3A%2210.1371%5C%2Fjournal.pone.0186881%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-24T09%3A25%3A53Z%22%7D%7D%2C%7B%22key%22%3A%22LS8LKXN2%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Glock%20et%20al.%22%2C%22parsedDate%22%3A%222017-05%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EGlock%2C%20Fabian%2C%20Mandy%20Vogel%2C%20Stephanie%20Naumann%2C%20Andreas%20Kuehnapfel%2C%20Markus%20Scholz%2C%20Andreas%20Hiemisch%2C%20Toralf%20Kirsten%2C%20et%20al.%20%26%23x201C%3BValidity%20and%20Intraobserver%20Reliability%20of%20Three-Dimensional%20Scanning%20Compared%20with%20Conventional%20Anthropometry%20for%20Children%20and%20Adolescents%20from%20a%20Population-Based%20Cohort%20Study.%26%23x201D%3B%20%3Ci%3EPediatric%20Research%3C%5C%2Fi%3E%2081%2C%20no.%205%20%28May%202017%29%3A%20736%26%23×2013%3B44.%20https%3A%5C%2F%5C%2Fdoi.org%5C%2F%3Ca%20class%3D%27zp-ItemURL%27%20target%3D%27_blank%27%20href%3D%2710.1038%5C%2Fpr.2016.274%27%3E10.1038%5C%2Fpr.2016.274%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Validity%20and%20Intraobserver%20Reliability%20of%20Three-Dimensional%20Scanning%20Compared%20with%20Conventional%20Anthropometry%20for%20Children%20and%20Adolescents%20from%20a%20Population-Based%20Cohort%20Study%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Fabian%22%2C%22lastName%22%3A%22Glock%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Stephanie%22%2C%22lastName%22%3A%22Naumann%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andreas%22%2C%22lastName%22%3A%22Kuehnapfel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Markus%22%2C%22lastName%22%3A%22Scholz%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andreas%22%2C%22lastName%22%3A%22Hiemisch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Toralf%22%2C%22lastName%22%3A%22Kirsten%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Kristin%22%2C%22lastName%22%3A%22Rieger%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22Koerner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Markus%22%2C%22lastName%22%3A%22Loeffler%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%5D%2C%22abstractNote%22%3A%22BACKGROUND%3A%20Conventional%20anthropometric%20measurements%20are%20time%20consuming%20and%20require%20well%20trained%20medical%20staff.%20To%20use%20three-dimensional%20whole%20body%20laser%20scanning%20in%20daily%20clinical%20work%2C%20validity%2C%20and%20reliability%20have%20to%20be%20confirmed.%5CnMETHODS%3A%20We%20compared%20a%20whole%20body%20laser%20scanner%20with%20conventional%20anthropometry%20in%20a%20group%20of%20473%20children%20and%20adolescents%20from%20the%20Leipzig%20Research%20Centre%20for%20Civilization%20Diseases%20%28LIFE-Child%29.%20Concordance%20correlation%20coefficients%20%28CCC%29%20were%20calculated%20separately%20for%20sex%2C%20weight%2C%20and%20age%20to%20assess%20validity.%20Overall%20CCC%20%28OCCC%29%20was%20used%20to%20analyze%20intraobserver%20reliability.%5CnRESULTS%3A%20Body%20height%20and%20the%20circumferences%20of%20waist%2C%20hip%2C%20upper%20arm%2C%20and%20calf%20had%20an%20%5C%22excellent%5C%22%20%28CCC%20%5Cu2265%200.9%29%3B%20neck%20and%20thigh%20circumference%2C%20a%20%5C%22good%5C%22%20%28CCC%20%5Cu2265%200.7%29%3B%20and%20head%20circumference%2C%20a%20%5C%22low%5C%22%20%28CCC%20%3C%200.5%29%20degree%20of%20concordance%20over%20the%20complete%20study%20population.%20We%20observed%20dependencies%20of%20validity%20on%20sex%2C%20weight%2C%20and%20age.%20Intraobserver%20reliability%20of%20both%20techniques%20is%20%5C%22excellent%5C%22%20%28OCCC%20%5Cu2265%200.9%29.%5CnCONCLUSION%3A%20Scanning%20is%20faster%2C%20requires%20less%20intensive%20staff%20training%20and%20provides%20more%20information.%20It%20can%20be%20used%20in%20an%20epidemiologic%20setting%20with%20children%20and%20adolescents%20but%20some%20measurements%20should%20be%20considered%20with%20caution%20due%20to%20reduced%20agreement%20with%20conventional%20anthropometry.%22%2C%22date%22%3A%22May%202017%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1038%5C%2Fpr.2016.274%22%2C%22ISSN%22%3A%221530-0447%22%2C%22url%22%3A%2210.1038%5C%2Fpr.2016.274%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-27T08%3A21%3A46Z%22%7D%7D%2C%7B%22key%22%3A%22ATVGL5IF%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Junge%20et%20al.%22%2C%22parsedDate%22%3A%222017-05%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EJunge%2C%20Jennifer%2C%20Christoph%20Engel%2C%20Mandy%20Vogel%2C%20Stephanie%20Naumann%2C%20Markus%20L%26%23xF6%3Bffler%2C%20Joachim%20Thiery%2C%20J%26%23xFC%3Brgen%20Kratzsch%2C%20Wieland%20Kiess%2C%20and%20Antje%20K%26%23xF6%3Brner.%20%26%23x201C%3BNeck%20Circumference%20Is%20Similarly%20Predicting%20for%20Impairment%20of%20Glucose%20Tolerance%20as%20Classic%20Anthropometric%20Parameters%20Among%20Healthy%20and%20Obese%20Children%20and%20Adolescents.%26%23x201D%3B%20%3Ci%3EJournal%20of%20Pediatric%20Endocrinology%20and%20Metabolism%3C%5C%2Fi%3E%2030%2C%20no.%206%20%28May%202017%29%3A%20643%26%23×2013%3B50.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1515%5C%2Fjpem-2017-0079%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1515%5C%2Fjpem-2017-0079%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Neck%20Circumference%20Is%20Similarly%20Predicting%20for%20Impairment%20of%20Glucose%20Tolerance%20as%20Classic%20Anthropometric%20Parameters%20Among%20Healthy%20and%20Obese%20Children%20and%20Adolescents%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jennifer%22%2C%22lastName%22%3A%22Junge%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christoph%22%2C%22lastName%22%3A%22Engel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Stephanie%22%2C%22lastName%22%3A%22Naumann%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Markus%22%2C%22lastName%22%3A%22L%5Cu00f6ffler%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Joachim%22%2C%22lastName%22%3A%22Thiery%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J%5Cu00fcrgen%22%2C%22lastName%22%3A%22Kratzsch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%5D%2C%22abstractNote%22%3A%22Background%3A%5CnThe%20objective%20of%20the%20study%20was%20to%20investigate%20the%20association%20of%20neck%20circumference%20%28NC%29%20to%20parameters%20of%20glucose%20homeostasis%20compared%20to%20classical%20anthropometric%20parameters%20of%20lean%20and%20obese%20children.%5CnMethods%3A%5CnThree%20dimensional%20%283D%29-body%20scanning%20quantified%20anthropometric%20%28height%2C%20weight%2C%20NC%2C%20hip%5C%2Fwaist%20circumference%2C%20BMI%29%20and%20metabolic%20parameters%20%28fasting%20plasma%20glucose%20%5BFPG%5D%2C%20insulin%2C%20HbA1c%2C%20oGTT%2C%20HOMA-IR%29%20were%20determined%20cross-sectionally%20in%201542%20participants%20%285%5Cu201318%20years%29.%5CnResults%3A%5CnNC%20was%20positively%20correlated%20with%20all%20metabolic%20parameters%2C%20except%20for%20FPG.%20For%20HbA1c%20there%20was%20only%20a%20modestly%20positive%20correlation.%20The%20associations%20between%20NC%20and%20glucose%20parameters%20were%20rather%20weak%2C%20while%20the%20correlation%20to%20insulin%20parameters%20were%20stronger.%20Overall%20the%20strongest%20association%20to%20glucose%20metabolism%20parameters%20was%20found%20for%20waist%20circumference%20%28WC%29%2C%20except%20for%20FPG%20and%202h-postload%20glucose.%20In%20multiple%20linear%20regression%20analyses%2C%20NC%20provided%20additional%20benefit%20beyond%20classical%20anthropometric%20indices%20to%20describe%20impairment%20of%20glucose%20homeostasis.%5CnConclusions%3A%5CnWe%20suggest%20that%20NC%20is%20comparable%20or%20additive%20to%20established%20anthropometric%20parameters%20but%20might%20not%20be%20superior%20to%20them.%20However%20NC%20is%20simple%20to%20measure%2C%20reproducible%20and%20may%20be%20considered%20in%20clinical%20practice%20as%20an%20additional%20measurement%20tool.%22%2C%22date%22%3A%222017-05%22%2C%22language%22%3A%22%22%2C%22DOI%22%3A%2210.1515%5C%2Fjpem-2017-0079%22%2C%22ISSN%22%3A%220334-018X%22%2C%22url%22%3A%22http%3A%5C%2F%5C%2Fwww.degruyter.com%5C%2Fview%5C%2Fj%5C%2Fjpem.2017.30.issue-6%5C%2Fjpem-2017-0079%5C%2Fjpem-2017-0079.xml%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-07T07%3A01%3A43Z%22%7D%7D%2C%7B%22key%22%3A%22G9T2XXHI%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Gram%5Cu00df%20et%20al.%22%2C%22parsedDate%22%3A%222016%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EGram%26%23xDF%3B%2C%20Manuela%2C%20Andreas%20Hiemisch%2C%20and%20Wieland%20Kiess.%20%26%23x201C%3BStellt%20%26%23xDC%3Bbergewicht%20ein%20Risiko%20f%26%23xFC%3Br%20die%20Entwicklung%20von%20Asthma%20bronchiale%20im%20Kindes-%20und%20Jugendalter%20dar%3F%26%23x201D%3B%20%3Ci%3EAdipositas%20-%20Ursachen%2C%20Folgeerkrankungen%2C%20Therapie%3C%5C%2Fi%3E%2010%2C%20no.%202%20%282016%29%3A%2088%26%23×2013%3B92.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1055%5C%2Fs-0037-1617702%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1055%5C%2Fs-0037-1617702%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Stellt%20%5Cu00dcbergewicht%20ein%20Risiko%20f%5Cu00fcr%20die%20Entwicklung%20von%20Asthma%20bronchiale%20im%20Kindes-%20und%20Jugendalter%20dar%3F%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Manuela%22%2C%22lastName%22%3A%22Gram%5Cu00df%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andreas%22%2C%22lastName%22%3A%22Hiemisch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%5D%2C%22abstractNote%22%3A%22In%20den%20letzten%20beiden%20Jahrzehnten%20stiegen%20die%20Pr%5Cu00e4valenzen%20von%20Asthma%20bronchiale%20und%20%5Cu00dcbergewicht%20parallel%20an.%20F%5Cu00fcr%20beide%20Erkrankungen%20werden%20%5Cu00e4hnliche%20Ursachen%20diskutiert%3A%20umweltbezogene%2C%20genetische%2C%20sozio%5Cu00f6konomische%20Faktoren%20und%20sogar%20die%20Einflussnahme%20durch%20Adipokine.%20Au%5Cu00dferdem%20r%5Cu00fcckte%20das%20%5Cu00dcbergewicht%20als%20potenzieller%20Ausl%5Cu00f6ser%20und%20beg%5Cu00fcnstigender%20Faktor%20von%20Asthma%20bronchiale%20in%20den%20Fokus%20der%20Forschung.%20Der%20BMI%20ist%20sowohl%20mit%20der%20Diagnose%20Asthma%20als%20auch%20mit%20dem%20Symptom%20%5Cu201ewheezing%5Cu201d%20positiv%20korreliert.%20%5Cu00dcbergewichtige%20Kinder%20weisen%20gr%5Cu00f6%5Cu00dfere%20IgESpiegel%20und%20h%5Cu00e4ufiger%20Atopien%20auf.%20Jedoch%20zeigen%20Kinder%20mit%20gr%5Cu00f6%5Cu00dferem%20BMI%20h%5Cu00e4ufiger%20nichtatopisches%20als%20atopisches%20Asthma%20bronchiale.%20Zudem%20sind%20allergische%20Tests%20wie%20bronchiale%20Hyperreagibilit%5Cu00e4t%20und%20Skin%20Prick%20Tests%20bei%20adip%5Cu00f6sen%20Kindern%20nicht%20h%5Cu00e4ufiger%20positiv%20als%20bei%20normalgewichtigen%20Kindern.%20Die%20Lungenfunktionswerte%20bei%20%5Cu00dcbergewicht%20werden%20h%5Cu00e4ufig%20als%20Minderung%20des%20Tiffeneau-Index%20%28FEV1%5C%2FFVK%29%20beschrieben.%20Allerdings%20ist%20auch%20hier%20der%20Zusammenhang%20noch%20unklar%2C%20vor%20allem%20die%20Reaktion%20adip%5Cu00f6ser%20Kinder%20auf%20medikament%5Cu00f6se%20Broncholyse%20als%20Bestandteil%20der%20Spirometrie-Testung.%20Die%20nicht%20durchg%5Cu00e4ngig%20einheitlichen%20und%20teilweise%20nicht%20signifikanten%20Studienergebnisse%20lassen%20daher%20nicht%20auf%20eine%20unmittelbare%20Verbindung%20von%20Asthma%20und%20Adipositas%20oder%20auf%20den%20Einfluss%20von%20Kovariablen%20auf%20deren%20Verh%5Cu00e4ltnis%20schlie%5Cu00dfen.%20Die%20LIFE%20Child-Kohorte%20soll%20zur%20Kl%5Cu00e4rung%20offener%20Fragen%20beitragen.%22%2C%22date%22%3A%222016%22%2C%22language%22%3A%22de%22%2C%22DOI%22%3A%2210.1055%5C%2Fs-0037-1617702%22%2C%22ISSN%22%3A%221865-1739%2C%202567-6334%22%2C%22url%22%3A%22http%3A%5C%2F%5C%2Fwww.thieme-connect.de%5C%2FDOI%5C%2FDOI%3F10.1055%5C%2Fs-0037-1617702%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-07T07%3A01%3A46Z%22%7D%7D%5D%7D
Kabbani, Noura, Holger Stepan, Matthias Blüher, Thomas Ebert, Ronny Baber, Mandy Vogel, Wieland Kiess, et al. “Association between TGFβ1 Levels in Cord Blood and Weight Progress in the First Year of Life.” Biomedicines 11, no. 8 (August 8, 2023): 2220. https://doi.org/10.3390/biomedicines11082220.
Pfäffle, Roland, Matthias Knüpfer, Melanie Göbert, Mandy Vogel, Ruth Gausche, Christoph Beger, Eberhard Keller, Antje Körner, Ulrich Thome, and Wieland Kiess. “Growth Patterns of Children With Short Stature in Adulthood According to Auxological Status and Maturity at Birth.” The Journal of Clinical Endocrinology and Metabolism 107, no. 12 (November 25, 2022): 3320–27. https://doi.org/2022112511292049000.
Vogelezang, Suzanne, Jonathan P. Bradfield, Early Growth Genetics Consortium, Struan F. A. Grant, Janine F. Felix, and Vincent W. V. Jaddoe. “Genetics of Early-Life Head Circumference and Genetic Correlations with Neurological, Psychiatric and Cognitive Outcomes.” BMC Medical Genomics 15, no. 1 (June 4, 2022): 124. https://doi.org/10.1186/s12920-022-01281-1.
Rönnecke, Elisa, Mandy Vogel, Sarah Bussler, Nico Grafe, Anne Jurkutat, Maike Schlingmann, Antje Koerner, and Wieland Kiess. “Age- and Sex-Related Percentiles of Skinfold Thickness, Waist and Hip Circumference, Waist-to-Hip Ratio and Waist-to-Height Ratio: Results from a Population-Based Pediatric Cohort in Germany (LIFE Child).” Obesity Facts 12, no. 1 (March 2019): 25–39. https://doi.org/10.1159/000494767.
Loeffler-Wirth, Henry, Mandy Vogel, Toralf Kirsten, Fabian Glock, Tanja Poulain, Antje Körner, Markus Loeffler, Wieland Kiess, and Hans Binder. “Longitudinal Anthropometry of Children and Adolescents Using 3d-Body Scanning.” PloS One 13, no. 9 (September 2018): e0203628. https://doi.org/10.1371/journal.pone.0203628.
Loeffler-Wirth, Henry, Mandy Vogel, Toralf Kirsten, Fabian Glock, Tanja Poulain, Antje Körner, Markus Loeffler, Wieland Kiess, and Hans Binder. “Body Typing of Children and Adolescents Using 3d-Body Scanning.” PloS One 12, no. 10 (October 2017): e0186881. https://doi.org/10.1371/journal.pone.0186881.
Glock, Fabian, Mandy Vogel, Stephanie Naumann, Andreas Kuehnapfel, Markus Scholz, Andreas Hiemisch, Toralf Kirsten, et al. “Validity and Intraobserver Reliability of Three-Dimensional Scanning Compared with Conventional Anthropometry for Children and Adolescents from a Population-Based Cohort Study.” Pediatric Research 81, no. 5 (May 2017): 736–44. https://doi.org/10.1038/pr.2016.274.
Junge, Jennifer, Christoph Engel, Mandy Vogel, Stephanie Naumann, Markus Löffler, Joachim Thiery, Jürgen Kratzsch, Wieland Kiess, and Antje Körner. “Neck Circumference Is Similarly Predicting for Impairment of Glucose Tolerance as Classic Anthropometric Parameters Among Healthy and Obese Children and Adolescents.” Journal of Pediatric Endocrinology and Metabolism 30, no. 6 (May 2017): 643–50. https://doi.org/10.1515/jpem-2017-0079.
Gramß, Manuela, Andreas Hiemisch, and Wieland Kiess. “Stellt Übergewicht ein Risiko für die Entwicklung von Asthma bronchiale im Kindes- und Jugendalter dar?” Adipositas – Ursachen, Folgeerkrankungen, Therapie 10, no. 2 (2016): 88–92. https://doi.org/10.1055/s-0037-1617702.
2390247
T52N9QLZ
allergy
1
chicago-fullnote-bibliography
50
date
desc
1
1
6748
https://home.uni-leipzig.de/lifechild/wp-content/plugins/zotpress/
%7B%22status%22%3A%22success%22%2C%22updateneeded%22%3Afalse%2C%22instance%22%3Afalse%2C%22meta%22%3A%7B%22request_last%22%3A0%2C%22request_next%22%3A0%2C%22used_cache%22%3Atrue%7D%2C%22data%22%3A%5B%7B%22key%22%3A%22YYBRDW2S%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Holvoet%20et%20al.%22%2C%22parsedDate%22%3A%222024-12-31%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EHolvoet%2C%20S%26%23xE9%3Bbastien%2C%20Francis%20Foata%2C%20Sophie%20Nutten%2C%20Ellen%20N%26%23xED%3B%20Cl%26%23xE9%3Birigh%2C%20Maya%20Shevlyakova%2C%20Cheong%20Kwong%20Chung%2C%20Gregory%20Lefevre%2C%20et%20al.%20%26%23x201C%3BImpact%20of%20Consumption%20of%20the%20Human%20Milk%20Oligosaccharides%202%26%23×2032%3B-FL%20and%20LNnT%20on%20Reduction%20of%20Risk%20of%20Allergic%20Sensitisation.%26%23x201D%3B%20%3Ci%3EFood%20and%20Agricultural%20Immunology%3C%5C%2Fi%3E%2035%2C%20no.%201%20%28December%2031%2C%202024%29%3A%202301703.%20%3Ca%20class%3D%27zp-ItemURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1080%5C%2F09540105.2023.2301703%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1080%5C%2F09540105.2023.2301703%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Impact%20of%20consumption%20of%20the%20human%20milk%20oligosaccharides%202%5Cu2032-FL%20and%20LNnT%20on%20reduction%20of%20risk%20of%20allergic%20sensitisation%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22S%5Cu00e9bastien%22%2C%22lastName%22%3A%22Holvoet%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Francis%22%2C%22lastName%22%3A%22Foata%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Sophie%22%2C%22lastName%22%3A%22Nutten%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ellen%22%2C%22lastName%22%3A%22N%5Cu00ed%20Cl%5Cu00e9irigh%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Maya%22%2C%22lastName%22%3A%22Shevlyakova%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Cheong%22%2C%22lastName%22%3A%22Kwong%20Chung%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Gregory%22%2C%22lastName%22%3A%22Lefevre%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Norbert%22%2C%22lastName%22%3A%22Sprenger%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tristan%22%2C%22lastName%22%3A%22Bourdeau%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Dominique%22%2C%22lastName%22%3A%22Donnicola%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mario%22%2C%22lastName%22%3A%22Noti%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Severine%22%2C%22lastName%22%3A%22Combremont%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Aristea%22%2C%22lastName%22%3A%22Binia%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Chiara%22%2C%22lastName%22%3A%22Nembrini%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Carine%22%2C%22lastName%22%3A%22Blanchard%22%7D%5D%2C%22abstractNote%22%3A%22Human%20Milk%20Oligosaccharides%20%28HMOs%29%20have%20been%20proposed%20to%20be%20instrumental%20in%20building%20immune%20competence.%20To%20explore%20the%20role%20of%20HMOs%20in%20allergy%20prevention%2C%20twenty-one%20HMOs%20were%20quantified%20in%20breast%20milk%20samples%20and%20associated%20with%20sensitisation%20in%20infants.%202%5Cu2032-fucosyllactose%20%282%5Cu2032-FL%29%20levels%20were%20positively%20associated%20with%20an%20increased%20risk%20of%20sensitisation%2C%20atopic%20dermatitis%20and%20recurrent%20skin%20rash.%20Interestingly%2C%202%5Cu2032-FL%20levels%2C%20ranging%20from%201.35%20to%201.95%20g%5C%2FL%2C%20were%20associated%20with%20a%20higher%20prevalence%20of%20non-allergic%20and%20non-sensitised%20infants.%20The%20role%20of%202%5Cu2032-FL%20and%20lacto-N-neotetraose%20%28LNnT%29%20was%20further%20investigated%20in%20allergic%20sensitisation%20models%20in%20vivo.%20Oral%20administration%20of%20HMOs%20decreased%20allergic%20sensitisation.%20This%20was%20associated%20with%20gut%20microbiota%20and%20short-chain%20fatty%20acid%20%28SCFA%29%20production%20changes.%20Aligned%20with%20the%20clinical%20associations%2C%20the%20decreased%20sensitisation%20was%20not%20observed%20with%20lower%20and%20higher%20tested%20doses%20of%20the%20HMOs%20supporting%20a%20U-shape%20association%20between%202%5Cu2032-FL%20and%20LNnT%20levels%20and%20allergic%20sensitisation%20risk%20reduction%20in%20humans%20and%20mice.%20Trial%20registration%3A%20ClinicalTrials.gov%20identifier%3A%20NCT02550236.%22%2C%22date%22%3A%222024-12-31%22%2C%22language%22%3A%22%22%2C%22DOI%22%3A%2210.1080%5C%2F09540105.2023.2301703%22%2C%22ISSN%22%3A%220954-0105%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1080%5C%2F09540105.2023.2301703%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222024-08-27T12%3A04%3A19Z%22%7D%7D%2C%7B%22key%22%3A%222CKZR3R6%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Keller%20et%20al.%22%2C%22parsedDate%22%3A%222021-04%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EKeller%2C%20Wiebke%2C%20Mandy%20Vogel%2C%20Freerk%20Prenzel%2C%20Jon%20Genuneit%2C%20Anne%20Jurkutat%2C%20Cornelia%20Hilbert%2C%20Andreas%20Hiemisch%2C%20Wieland%20Kiess%2C%20and%20Tanja%20Poulain.%20%26%23x201C%3BAtopic%20Diseases%20in%20Children%20and%20Adolescents%20Are%20Associated%20with%20Behavioural%20Difficulties.%26%23x201D%3B%20%3Ci%3EBMC%20Pediatrics%3C%5C%2Fi%3E%2021%2C%20no.%201%20%28April%202021%29%3A%20197.%20%3Ca%20class%3D%27zp-ItemURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs12887-021-02663-7%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs12887-021-02663-7%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Atopic%20Diseases%20in%20Children%20and%20Adolescents%20Are%20Associated%20with%20Behavioural%20Difficulties%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wiebke%22%2C%22lastName%22%3A%22Keller%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Freerk%22%2C%22lastName%22%3A%22Prenzel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jon%22%2C%22lastName%22%3A%22Genuneit%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anne%22%2C%22lastName%22%3A%22Jurkutat%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Cornelia%22%2C%22lastName%22%3A%22Hilbert%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andreas%22%2C%22lastName%22%3A%22Hiemisch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%5D%2C%22abstractNote%22%3A%22BACKGROUND%3A%20Atopic%20diseases%20and%20behavioural%20difficulties%20in%20children%20have%20both%20been%20on%20the%20rise%20in%20recent%20decades.%20This%20study%20seeks%20to%20assess%20associations%20between%20atopic%20diseases%20and%20behavioural%20difficulties%2C%20examining%20the%20differences%20considering%20child%20age%20and%20how%20behavioural%20difficulties%20were%20reported%20%28via%20self-report%20or%20parent-report%29.%5CnMETHODS%3A%20Data%20on%20behavioural%20difficulties%2C%20assessed%20through%20the%20Strengths%20and%20Difficulties%20Questionnaire%20%28SDQ%29%2C%20and%20on%20atopic%20diseases%2C%20assessed%20through%20the%20participant%27s%20medical%20history%2C%20were%20available%20for%202701%20study%20participants%20aged%203%20to%2018%5Cu2009years.%20Associations%20between%20atopic%20diseases%20and%20behavioural%20difficulties%20were%20evaluated%20using%20linear%20regression%20analyses.%20We%20split%20the%20study%20sample%20into%20two%20groups.%20I%3A%203-to%2010-year-olds%5C%2Fparent-reported%20SDQ%20%28n%5Cu00a0%3D%5Cu20091764%29%2C%20II%3A%2011-%20to%2018-year-olds%5C%2Fparent-reported%20SDQ%20%28n%5Cu00a0%3D%5Cu2009937%29%20and%20self-reported%20SDQ%20%28n%5Cu00a0%3D%5Cu2009915%29.%20All%20analyses%20were%20adjusted%20for%20age%2C%20gender%2C%20and%20socioeconomic%20status.%5CnRESULTS%3A%20In%20younger%20children%2C%20atopic%20dermatitis%20was%20strongly%20associated%20with%20higher%20total%20difficulties%20scores%2C%20more%20emotional%20problems%20and%20conduct%20problems%2C%20and%20more%20symptoms%20of%20hyperactivity%5C%2Finattention.%20Parents%20reported%20higher%20total%20difficulties%20scores%2C%20more%20emotional%20problems%2C%20and%20more%20peer-relationship%20problems%20for%20adolescents%20with%20bronchial%20asthma%20and%20other%20allergies%2C%20whereas%20the%20adolescents%20themselves%20reported%20more%20peer%20relationship%20problems.%5CnCONCLUSION%3A%20In%20younger%20children%2C%20atopic%20dermatitis%20is%20associated%20with%20internalizing%20and%20externalizing%20problems.%20In%20adolescents%2C%20bronchial%20asthma%20and%20other%20allergies%20are%20associated%20with%20a%20greater%20level%20of%20internalizing%20problems%20only.%20The%20findings%20further%20suggest%20that%20parents%20of%20adolescents%20are%20more%20likely%20to%20perceive%20associations%20between%20atopic%20diseases%20and%20behavioural%20difficulties%20than%20the%20adolescents%20themselves.%22%2C%22date%22%3A%222021-04%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1186%5C%2Fs12887-021-02663-7%22%2C%22ISSN%22%3A%221471-2431%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs12887-021-02663-7%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-27T08%3A29%3A16Z%22%7D%7D%2C%7B%22key%22%3A%22YULVGQEH%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22H%5Cu00e4ndel%20et%20al.%22%2C%22parsedDate%22%3A%222018-10%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EH%26%23xE4%3Bndel%2C%20Norman%2C%20Thomas%20Mothes%2C%20David%20Petroff%2C%20Ronny%20Baber%2C%20Anne%20Jurkutat%2C%20Gunter%20Flemming%2C%20Wieland%20Kiess%2C%20et%20al.%20%26%23x201C%3BWill%20the%20Real%20Coeliac%20Disease%20Please%20Stand%20Up%3F%20Coeliac%20Disease%20Prevalence%20in%20the%20German%20LIFE%20Child%20Study.%26%23x201D%3B%20%3Ci%3EJournal%20of%20Pediatric%20Gastroenterology%20and%20Nutrition%3C%5C%2Fi%3E%2067%2C%20no.%204%20%28October%202018%29%3A%20494.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1097%5C%2FMPG.0000000000002052%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1097%5C%2FMPG.0000000000002052%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Will%20the%20Real%20Coeliac%20Disease%20Please%20Stand%20Up%3F%20Coeliac%20Disease%20Prevalence%20in%20the%20German%20LIFE%20Child%20Study%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Norman%22%2C%22lastName%22%3A%22H%5Cu00e4ndel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Thomas%22%2C%22lastName%22%3A%22Mothes%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22David%22%2C%22lastName%22%3A%22Petroff%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ronny%22%2C%22lastName%22%3A%22Baber%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anne%22%2C%22lastName%22%3A%22Jurkutat%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Gunter%22%2C%22lastName%22%3A%22Flemming%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andreas%22%2C%22lastName%22%3A%22Hiemisch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wolfgang%22%2C%22lastName%22%3A%22Schlumberger%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Joachim%22%2C%22lastName%22%3A%22Thiery%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Johannes%22%2C%22lastName%22%3A%22Wolf%22%7D%5D%2C%22abstractNote%22%3A%22Objectives%3A%5Cu00a0Assessing%20the%20seroprevalence%20and%20the%20prevalence%20of%20definite%20coeliac%20disease%20%28CD%29%20in%20the%20German%20LIFE%20Child%20Health%20study%20cohort%20including%20immunoglobulin%20A%20%28IgA%29%20antibodies%20against%20tissue%20transglutaminase%20%28IgA-TTG%29%20in%20addition%20to%20IgG%20antibodies%20against%20deamidated%20gliadin%20peptides%20%28IgG-DGP%29%20and%20human%20leukocyte%20antigen%20%28HLA%29-DQ2%5C%2F8%20genotyping.%5CnMethods%3A%5Cu00a0Samples%20from%20children%20and%20adolescents%20were%20first%20screened%20for%20IgA-TTG%20and%20IgG-DGP.%20If%20IgA-TTG%20was%20above%200.5%20times%20the%20upper%20limit%20of%20normal%20and%5C%2For%20IgG-DGP%20was%20positive%2C%20IgA%20antibodies%20against%20endomysium%20%28IgA-EmA%29%20were%20measured%2C%20and%20HLA%20was%20genotyped.%20In%20patients%20with%20only%20IgG-DGP%20positivity%2C%20total%20IgA%20was%20assayed.%20Subjects%20with%20suspicious%20results%20were%20followed%20up%20serologically%20and%2C%20in%20case%20of%20repeatedly%20positive%20antibody%20results%2C%20invited%20for%20a%20personal%20interview.%20Further%20diagnostic%20data%20were%20obtained%20independent%20from%20our%20study.%5CnResults%3A%5Cu00a0We%20screened%202363%20children%27s%20blood%20samples%20collected%20from%202011%20to%202015.%20The%20seroprevalence%2C%20that%20is%2C%20IgA-TTG%20and%5C%2For%20IgA-EmA%20positivity%20or%20IgG-DGP%20positivity%20with%20IgA%20%3C0.05%20g%5C%2FL%2C%20was%201.57%25%20%2895%25%20confidence%20interval%20%5BCI95%25%5D%201.14%5Cu20132.15%29.%20The%20prevalence%20of%20suspected%20CD%2C%20that%20is%2C%20seroprevalence%20and%20compatible%20HLA%20genotype%20with%20hitherto%20unknown%20mucosal%20damage%2C%20was%201.35%25%20%28CI95%25%200.96%5Cu20131.91%29.%20Definite%20CD%2C%20that%20is%2C%20seropositivity%20accompanied%20by%20positive%20intestinal%20biopsy%20or%20IgA-TTG%20%5Cu2265%2010%20%5Cu00d7%20upper%20limit%20of%20normal%2C%20was%20found%20in%200.42%25%20%28CI95%25%200.22%5Cu20130.80%29.%20Seven%20children%20claimed%20to%20have%20CD.%20The%20HLA%20haplotype%2C%20however%2C%20matched%20in%20only%204%20of%20them%20resulting%20in%20an%20overall%20CD%20prevalence%20of%20at%20least%200.59%25%20%28CI95%25%200.34%5Cu20131.02%29.%20Thirteen%20unclear%20cases%20remained%3B%20therefore%2C%20the%20prevalence%20may%20even%20be%20higher.%5CnConclusions%3A%5Cu00a0The%20prevalence%20of%20definite%20CD%20in%20a%20population-representative%20German%20cohort%20is%20higher%20than%20previously%20described.%20HLA-DQ%20typing%20is%20helpful%20to%20identify%20false-positive%20IgA-TTG%20patients%20negative%20for%20IgA-EmA%20and%5C%2For%20IgG-DGP%20under%20screening%20conditions%20and%20unmasks%20possible%20misdiagnoses%20of%20CD.%22%2C%22date%22%3A%22October%202018%22%2C%22language%22%3A%22en-US%22%2C%22DOI%22%3A%2210.1097%5C%2FMPG.0000000000002052%22%2C%22ISSN%22%3A%220277-2116%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fjournals.lww.com%5C%2Fjpgn%5C%2FFulltext%5C%2F2018%5C%2F10000%5C%2FWill_the_Real_Coeliac_Disease_Please_Stand_Up_.15.aspx%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-24T08%3A28%3A14Z%22%7D%7D%2C%7B%22key%22%3A%22N4K2INFR%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Klamt%20et%20al.%22%2C%22parsedDate%22%3A%222015-11%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EKlamt%2C%20Sabine%2C%20Mandy%20Vogel%2C%20Thomas%20M.%20Kapellen%2C%20Andreas%20Hiemisch%2C%20Freerk%20Prenzel%2C%20Silke%20Zachariae%2C%20Uta%20Ceglarek%2C%20Joachim%20Thiery%2C%20and%20Wieland%20Kiess.%20%26%23x201C%3BAssociation%20Between%20Ige-Mediated%20Allergies%20and%20Diabetes%20Mellitus%20Type%201%20in%20Children%20and%20Adolescents.%26%23x201D%3B%20%3Ci%3EPediatric%20Diabetes%3C%5C%2Fi%3E%2016%2C%20no.%207%20%28November%202015%29%3A%20493%26%23×2013%3B503.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fpedi.12298%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fpedi.12298%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Association%20Between%20Ige-Mediated%20Allergies%20and%20Diabetes%20Mellitus%20Type%201%20in%20Children%20and%20Adolescents%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Sabine%22%2C%22lastName%22%3A%22Klamt%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Thomas%20M.%22%2C%22lastName%22%3A%22Kapellen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andreas%22%2C%22lastName%22%3A%22Hiemisch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Freerk%22%2C%22lastName%22%3A%22Prenzel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Silke%22%2C%22lastName%22%3A%22Zachariae%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Uta%22%2C%22lastName%22%3A%22Ceglarek%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Joachim%22%2C%22lastName%22%3A%22Thiery%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%5D%2C%22abstractNote%22%3A%22BACKGROUND%3A%20Type%201%20diabetes%20mellitus%20%28T1DM%29%20is%20characterized%20by%20an%20immunological%20reaction%20that%20is%20dominated%20by%20type-1%20T%20helper%20%28Th1%29%20cells%2C%20whereas%20immunoglobulin%20E%20%28IgE%29-mediated%20allergies%20are%20associated%20with%20Th2%20cell.%20According%20to%20the%20Th1%5C%2FTh2-hypothesis%2C%20the%20immune%20system%20is%20said%20to%20either%20develop%20into%20the%20direction%20of%20Th1%20or%20Th2%20cells.%20This%20would%20mean%20that%20a%20child%20developing%20T1DM%20is%20unlikely%20to%20develop%20an%20IgE-mediated%20allergy%20and%20vice%20versa.%5CnOBJECTIVE%3A%20The%20aim%20of%20the%20study%20was%20to%20investigate%20the%20association%20between%20the%20prevalence%20of%20T1DM%20and%20IgE-mediated%20allergies.%5CnMETHODS%3A%20We%20designed%20a%20prospective%20case%20control%20study%20with%2094%20children%20and%20adolescents%20with%20T1DM%20and%20188%20age-%20and%20sex-matched%20control%20children.%20The%20basis%20of%20our%20investigations%20was%20a%20questionnaire%20concerning%20the%20family%20and%20children%27s%20history%20as%20to%20the%20presence%20of%20IgE-mediated%20allergies.%20Moreover%2C%20the%20following%20blood%20investigations%20were%20done%3A%20total%20serum%20IgE%2C%20specific%20IgE%20antibodies%20to%20major%20inhalant%20allergens%2C%20and%20a%20multiplex%20cytokine%20analysis%20measuring%20levels%20of%20specific%20cytokines%20representing%20either%20Th1-%20or%20Th2-%20cytokines.%5CnRESULTS%3A%20Children%20with%20T1DM%20reported%20the%20presence%20of%20IgE-mediated%20allergies%20significantly%20more%20often%20than%20children%20of%20the%20control%20group.%20Children%20with%20T1DM%20had%20significantly%20higher%20tumor%20necrosis%20factor%20alpha%20%28TNF%5Cu03b1%29%20levels%20than%20healthy%20controls.%20Levels%20of%20interleukin-2%20%28IL-2%29%20and%20IL-6%20were%20higher%20in%20the%20groups%20of%20children%20with%20the%20presence%20of%20a%20personal%20history%20of%20allergies%2C%20regardless%20of%20the%20presence%20of%20T1DM.%5CnCONCLUSIONS%3A%20Our%20results%20suggest%20that%20T1DM%20is%20associated%20with%20a%20higher%20risk%20of%20a%20self-reported%20presence%20of%20IgE-mediated%20allergies%20and%20that%20the%20Th1%5C%2FTh2-hypothesis%20may%20be%20an%20oversimplification.%22%2C%22date%22%3A%22November%202015%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1111%5C%2Fpedi.12298%22%2C%22ISSN%22%3A%221399-5448%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-27T08%3A32%3A21Z%22%7D%7D%5D%7D
Holvoet, Sébastien, Francis Foata, Sophie Nutten, Ellen Ní Cléirigh, Maya Shevlyakova, Cheong Kwong Chung, Gregory Lefevre, et al. “Impact of Consumption of the Human Milk Oligosaccharides 2′-FL and LNnT on Reduction of Risk of Allergic Sensitisation.” Food and Agricultural Immunology 35, no. 1 (December 31, 2024): 2301703. https://doi.org/10.1080/09540105.2023.2301703.
Keller, Wiebke, Mandy Vogel, Freerk Prenzel, Jon Genuneit, Anne Jurkutat, Cornelia Hilbert, Andreas Hiemisch, Wieland Kiess, and Tanja Poulain. “Atopic Diseases in Children and Adolescents Are Associated with Behavioural Difficulties.” BMC Pediatrics 21, no. 1 (April 2021): 197. https://doi.org/10.1186/s12887-021-02663-7.
Händel, Norman, Thomas Mothes, David Petroff, Ronny Baber, Anne Jurkutat, Gunter Flemming, Wieland Kiess, et al. “Will the Real Coeliac Disease Please Stand Up? Coeliac Disease Prevalence in the German LIFE Child Study.” Journal of Pediatric Gastroenterology and Nutrition 67, no. 4 (October 2018): 494. https://doi.org/10.1097/MPG.0000000000002052.
Klamt, Sabine, Mandy Vogel, Thomas M. Kapellen, Andreas Hiemisch, Freerk Prenzel, Silke Zachariae, Uta Ceglarek, Joachim Thiery, and Wieland Kiess. “Association Between Ige-Mediated Allergies and Diabetes Mellitus Type 1 in Children and Adolescents.” Pediatric Diabetes 16, no. 7 (November 2015): 493–503. https://doi.org/10.1111/pedi.12298.
2390247
T52N9QLZ
voice
1
chicago-fullnote-bibliography
50
date
desc
1
1
6748
https://home.uni-leipzig.de/lifechild/wp-content/plugins/zotpress/
%7B%22status%22%3A%22success%22%2C%22updateneeded%22%3Afalse%2C%22instance%22%3Afalse%2C%22meta%22%3A%7B%22request_last%22%3A0%2C%22request_next%22%3A0%2C%22used_cache%22%3Atrue%7D%2C%22data%22%3A%5B%7B%22key%22%3A%22HLWE9S7M%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Dienerowitz%20et%20al.%22%2C%22parsedDate%22%3A%222021-12%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EDienerowitz%2C%20Tobias%2C%20Thomas%20Peschel%2C%20Mandy%20Vogel%2C%20Tanja%20Poulain%2C%20Christoph%20Engel%2C%20Wieland%20Kiess%2C%20Michael%20Fuchs%2C%20and%20Thomas%20Berger.%20%26%23x201C%3BEstablishing%20Normative%20Data%20on%20Singing%20Voice%20Parameters%20of%20Children%20and%20Adolescents%20with%20Average%20Singing%20Activity%20Using%20the%20Voice%20Range%20Profile.%26%23x201D%3B%20%3Ci%3EFolia%20Phoniatrica%20et%20Logopaedica%3A%20Official%20Organ%20of%20the%20International%20Association%20of%20Logopedics%20and%20Phoniatrics%20%28IALP%29%3C%5C%2Fi%3E%2073%2C%20no.%206%20%28December%202021%29.%20%3Ca%20class%3D%27zp-ItemURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1159%5C%2F000513521%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1159%5C%2F000513521%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Establishing%20Normative%20Data%20on%20Singing%20Voice%20Parameters%20of%20Children%20and%20Adolescents%20with%20Average%20Singing%20Activity%20Using%20the%20Voice%20Range%20Profile%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tobias%22%2C%22lastName%22%3A%22Dienerowitz%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Thomas%22%2C%22lastName%22%3A%22Peschel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christoph%22%2C%22lastName%22%3A%22Engel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Michael%22%2C%22lastName%22%3A%22Fuchs%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Thomas%22%2C%22lastName%22%3A%22Berger%22%7D%5D%2C%22abstractNote%22%3A%22PURPOSE%3A%20The%20purpose%20of%20this%20study%20was%20to%20establish%20and%20characterize%20age-%20and%20gender-specific%20normative%20data%20of%20the%20singing%20voice%20using%20the%20voice%20range%20profile%20for%20clinical%20diagnostics.%20Furthermore%2C%20associations%20between%20the%20singing%20voice%20and%20the%20socioeconomic%20status%20were%20examined.%5CnMETHODS%3A%20Singing%20voice%20profiles%20of%201%2C578%20mostly%20untrained%20children%20aged%20between%207.0%20and%2016.11%20years%20were%20analyzed.%20Participants%20had%20to%20reproduce%20sung%20tones%20at%20defined%20pitches%2C%20resulting%20in%20maximum%20and%20minimum%20fundamental%20frequency%20and%20sound%20pressure%20level%20%28SPL%29.%20In%20addition%2C%20maximum%20phonation%20time%20%28MPT%29%20was%20measured.%20Percentile%20curves%20of%20frequency%2C%20SPL%20and%20MPT%20were%20estimated.%20To%20examine%20the%20associations%20of%20socioeconomic%20status%2C%20multivariate%20analyses%20adjusted%20for%20age%20and%20sex%20were%20performed.%5CnRESULTS%3A%20In%20boys%2C%20the%20mean%20of%20the%20highest%20frequency%20was%20750.9%20Hz%20and%20lowered%20to%20397.1%20Hz%20with%20increasing%20age.%20Similarly%2C%20the%20minimum%20frequency%20was%20194.4%20Hz%20and%20lowered%20to%2091.9%20Hz.%20In%20girls%2C%20the%20mean%20maximum%20frequency%20decreased%20from%20754.9%20to%20725.3%20Hz.%20The%20mean%20minimum%20frequency%20lowered%20from%20202.4%20to%20175.0%20Hz.%20For%20both%20sexes%2C%20the%20mean%20frequency%20range%20%5Cu2206f%20showed%20a%20constant%20range%20of%20roughly%2024%20semitones.%20The%20MPT%20increased%20with%20age%2C%20for%20boys%20and%20girls.%20There%20was%20neither%20an%20effect%20of%20age%20nor%20sex%20on%20SPLmin%20or%20SPLmax%2C%20ranging%20between%2052.6%20and%2054.1%20dBA%20and%20between%2086.5%20and%2082.8%20dBA%2C%20respectively.%20Socioeconomic%20status%20was%20not%20associated%20with%20the%20above-mentioned%20variables.%5CnCONCLUSION%3A%20To%20our%20knowledge%2C%20this%20study%20is%20the%20first%20to%20present%20large%20normative%20data%20on%20the%20singing%20voice%20in%20childhood%20and%20adolescence%20based%20on%20a%20high%20number%20of%20measurements.%20In%20addition%2C%20we%20provide%20percentile%20curves%20for%20practical%20application%20in%20clinic%20and%20vocal%20pedagogy%20which%20may%20be%20applied%20to%20distinguish%20between%20normal%20and%20pathological%20singing%20voice.%22%2C%22date%22%3A%222021-12%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1159%5C%2F000513521%22%2C%22ISSN%22%3A%221421-9972%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1159%5C%2F000513521%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-07T07%3A01%3A51Z%22%7D%7D%2C%7B%22key%22%3A%22IYSC8JL8%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Berger%20et%20al.%22%2C%22parsedDate%22%3A%222020-12%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EBerger%2C%20Thomas%2C%20Sylvia%20Meuret%2C%20Christoph%20Engel%2C%20Mandy%20Vogel%2C%20Wieland%20Kiess%2C%20Michael%20Fuchs%2C%20and%20Tanja%20Poulain.%20%26%23x201C%3B%5BDetection%20of%20Relevant%20Changes%20in%20the%20Speaking%20Voice%20of%20Women%20Measured%20by%20the%20Speaking%20Voice%20Profile%5D.%26%23x201D%3B%20%3Ci%3ELaryngo-%20Rhino-%20Otologie%3C%5C%2Fi%3E%2C%20December%202020.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1055%5C%2Fa-1327-4275%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1055%5C%2Fa-1327-4275%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22%5BDetection%20of%20Relevant%20Changes%20in%20the%20Speaking%20Voice%20of%20Women%20Measured%20by%20the%20Speaking%20Voice%20Profile%5D%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Thomas%22%2C%22lastName%22%3A%22Berger%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Sylvia%22%2C%22lastName%22%3A%22Meuret%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christoph%22%2C%22lastName%22%3A%22Engel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Michael%22%2C%22lastName%22%3A%22Fuchs%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%5D%2C%22abstractNote%22%3A%22BACKGROUND%3A%20A%20healthy%20voice%20serves%20us%20as%20a%20basis%20for%20communication%20and%20an%20indispensable%20tool%20in%20a%20modern%20society%20with%20a%20growing%20number%20of%20vocal-intensive%20professions.%20There%20are%20indications%20that%20the%20average%20frequency%20of%20the%20speaking%20voice%20of%20women%20has%20decreased%20in%20recent%20years%20and%20is%20approaching%20that%20of%20men%20in%20the%20sense%20of%20sociophony.%20An%20epidemiological%20prospective%20cohort%20study%20will%20investigate%20the%20influences%20of%20age%2C%20personality%20traits%20and%20socio-demographic%20factors%20on%20the%20speaking%20voice%20of%20women.%5CnMATERIAL%20AND%20METHODS%3A%20Within%20the%20framework%20of%20a%20standardized%20examination%20procedure%2C%20the%20speaking%20voice%20of%202478%20voice-healthy%20female%20participants%20between%205%20and83%20years%20of%20age%20was%20registered%20in%204%20different%20intensity%20levels%20%28softest%20voice%2C%20conversational%20voice%2C%20classroom%20voice%20and%20shouting%20voice%29.%20Subsequently%2C%20the%20collected%20values%20for%20frequency%20and%20loudness%20of%20the%20different%20intensity%20levels%20were%20examined%20for%20correlation%20with%20age%20and%20results%20from%20questionnaires%20on%20personality%20%28FFFK%20and%20BFI-10%29%2C%20on%20%28mental%29%20health%20%28Patient-Health-Questionnaire%20-%20PHQ%29%20and%20on%20socio-economic%20status%20%28SES%29.%5CnRESULTS%3A%20Significant%20age-related%20influences%20on%20the%20speaking%20voice%20could%20be%20demonstrated%20for%20all%20voice%20intensities.%20For%20the%20personality%20traits%20investigated%2C%20significant%20positive%20correlations%20between%20the%20volume%20of%20the%20calling%20and%20speaking%20voice%20and%20extraversion%20were%20found.%20For%20the%20frequency%20of%20the%20softest%20voice%20and%20speaking%20voice%2C%20significant%20correlations%20were%20found%20for%20the%20personality%20traits%20of%20extraversion%20and%20tolerance.%20While%20no%20significant%20associations%20were%20found%20between%20the%20voice%20parameters%20of%20the%20speaking%20voice%20and%20the%20PHQ%2C%20it%20was%20found%20that%20the%20SES%20has%20a%20significant%20influence%20on%20both%20frequency%20and%20intensity.%5CnCONCLUSION%3A%20In%20addition%20to%20age-related%20changes%2C%20relevant%20influences%20of%20personality%20traits%20and%20the%20SES%20on%20speaking%20voice%20parameters%20in%20women%20were%20confirmed%2C%20which%20should%20be%20considered%20in%20clinical%20care%20of%20dysphonia.%22%2C%22date%22%3A%222020-12%22%2C%22language%22%3A%22ger%22%2C%22DOI%22%3A%2210.1055%5C%2Fa-1327-4275%22%2C%22ISSN%22%3A%221438-8685%22%2C%22url%22%3A%22http%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1055%5C%2Fa-1327-4275%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-27T08%3A34%3A05Z%22%7D%7D%2C%7B%22key%22%3A%22JDTTKV5E%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Berger%20et%20al.%22%2C%22parsedDate%22%3A%222019-07%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EBerger%2C%20Thomas%2C%20Thomas%20Peschel%2C%20Mandy%20Vogel%2C%20Diana%20Pietzner%2C%20Tanja%20Poulain%2C%20Anne%20Jurkutat%2C%20Sylvia%20Meuret%2C%20Christoph%20Engel%2C%20Wieland%20Kiess%2C%20and%20Michael%20Fuchs.%20%26%23x201C%3BSpeaking%20Voice%20in%20Children%20and%20Adolescents%3A%20Normative%20Data%20and%20Associations%20with%20Bmi%2C%20Tanner%20Stage%2C%20and%20Singing%20Activity.%26%23x201D%3B%20%3Ci%3EJournal%20of%20Voice%3C%5C%2Fi%3E%2033%2C%20no.%204%20%28July%202019%29%3A%20580.e21-580.e30.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.jvoice.2018.01.006%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.jvoice.2018.01.006%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Speaking%20Voice%20in%20Children%20and%20Adolescents%3A%20Normative%20Data%20and%20Associations%20with%20Bmi%2C%20Tanner%20Stage%2C%20and%20Singing%20Activity%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Thomas%22%2C%22lastName%22%3A%22Berger%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Thomas%22%2C%22lastName%22%3A%22Peschel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Diana%22%2C%22lastName%22%3A%22Pietzner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anne%22%2C%22lastName%22%3A%22Jurkutat%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Sylvia%22%2C%22lastName%22%3A%22Meuret%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christoph%22%2C%22lastName%22%3A%22Engel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Michael%22%2C%22lastName%22%3A%22Fuchs%22%7D%5D%2C%22abstractNote%22%3A%22Objectives%5CnThe%20aim%20of%20this%20study%20was%20to%20establish%20normative%20data%20concerning%20the%20speaking%20voice%20of%20children%20and%20adolescents%20for%20clinical%20diagnostics.%5CnStudy%20Design%5CnPopulation-based%20mixed%20cross-sectional%20and%20longitudinal%20childhood%20cohort%20study.%5CnMethods%5CnNormative%20data%20measuring%20the%20speaking%20voice%20profile%20of%201352%20male%20and%201274%20female%20participants%20aged%206%20to%2017%20years%20were%20collected.%20To%20evaluate%20the%20voice%20range%2C%20five%20different%20intensity%20levels%20as%20the%20quietest%20voicing%20speaking%20voice%20%28Level%20I%29%2C%20conversational%20voice%20%28Level%20II%29%2C%20classroom%20voice%20%28Level%20III%29%2C%20shouting%20voice%20%28Level%20IV%29%2C%20and%20again%20the%20quietest%20speaking%20voice%20%28Level%20V%29%20were%20investigated.%20Multivariable%20analyses%20were%20performed%20to%20describe%20the%20effects%20of%20body%20mass%20index%2C%20Tanner%20stage%2C%20and%20singing%20activity%20on%20the%20outcome%20variables.%5CnResults%5CnA%20clear%20distinction%20in%20frequencies%20and%20sound%20pressure%20levels%20between%20the%20five%20different%20voice%20levels%20can%20be%20found%20in%20both%20genders.%20In%20females%20the%20mean%20fundamental%20frequency%20of%20the%20conversational%20voice%20lowers%20from%20223.3%20to%20205.8%5Cu2009Hz.%20In%20male%20participants%20it%20lowers%20from%20223.3%20to%20102.3%5Cu2009Hz.%20The%20most%20substantial%20decrease%20in%20the%20fundamental%20frequency%20of%20the%20speaking%20voice%20in%20boys%20occurs%20at%2013.5%20years.%20Girls%20show%20an%20almost%20continuous%20decline%20in%20their%20fundamental%20frequency.%20Only%20the%20Tanner%20stage%20showed%20significant%20positive%20relationships%20with%20the%20grade%20of%20lowering%20of%20the%20fundamental%20frequency%20in%20both%20sexes.%5CnConclusions%5CnIt%20was%20shown%20that%20the%20investigation%20of%20the%20speaking%20voice%20using%20predefined%20intensity-levels%20represents%20a%20feasible%20examination%20for%20children%20and%20adolescents.%20This%20study%20provides%20reference%20data%20on%20the%20range%20and%20age-adjusted%20normative%20values%20of%20the%20speaking%20voice.%22%2C%22date%22%3A%22July%2C%202019%22%2C%22language%22%3A%22%22%2C%22DOI%22%3A%2210.1016%5C%2Fj.jvoice.2018.01.006%22%2C%22ISSN%22%3A%220892-1997%22%2C%22url%22%3A%22http%3A%5C%2F%5C%2Fwww.sciencedirect.com%5C%2Fscience%5C%2Farticle%5C%2Fpii%5C%2FS0892199717304186%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-23T10%3A27%3A14Z%22%7D%7D%2C%7B%22key%22%3A%22MJXQVR9H%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Poulain%20et%20al.%22%2C%22parsedDate%22%3A%222018-10%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EPoulain%2C%20Tanja%2C%20Michael%20Fuchs%2C%20Mandy%20Vogel%2C%20Anne%20Jurkutat%2C%20Andreas%20Hiemisch%2C%20Wieland%20Kiess%2C%20and%20Thomas%20Berger.%20%26%23x201C%3BAssociations%20of%20Speaking-Voice%20Parameters%20with%20Personality%20and%20Behavior%20in%20School-Aged%20Children.%26%23x201D%3B%20%3Ci%3EJournal%20of%20Voice%3C%5C%2Fi%3E%20online%20ahead%20of%20print%2C%20no.%2034%20%28October%202018%29%3A%203.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.jvoice.2018.09.022%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1016%5C%2Fj.jvoice.2018.09.022%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Associations%20of%20Speaking-Voice%20Parameters%20with%20Personality%20and%20Behavior%20in%20School-Aged%20Children%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Michael%22%2C%22lastName%22%3A%22Fuchs%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anne%22%2C%22lastName%22%3A%22Jurkutat%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andreas%22%2C%22lastName%22%3A%22Hiemisch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Thomas%22%2C%22lastName%22%3A%22Berger%22%7D%5D%2C%22abstractNote%22%3A%22Objectives%5CnPrevious%20studies%20suggest%20a%20link%20between%20voice%20disorders%20and%20personality%20traits.%20However%2C%20nearly%20nothing%20is%20known%20about%20the%20relationship%20between%20personality%20and%20voice%20parameters%20in%20healthy%20children.%20The%20present%20study%20investigated%20associations%20between%20children%27s%20personality%20and%20the%20intensity%20and%20frequency%20of%20their%20speaking%20voice.%5CnStudy%20Design%5CnThis%20is%20a%20cross-sectional%20analysis.%5CnMethods%5CnThe%20study%20participants%20included%20871%20German%20children%20aged%20from%207%20to%2014%20who%20had%20not%20yet%20experienced%20voice%20change%20in%20puberty.%20Within%20the%20framework%20of%20the%20LIFE%20Child%20study%2C%20all%20participants%20were%20asked%20to%20perform%20a%20speaking-voice%20task%20at%20four%20different%20intensity%20levels%20%28quietest%2C%20conversational%2C%20presentation%2C%20and%20shouting%20voice%29.%20Associations%20of%20fundamental%20frequency%20and%20voice%20intensity%20with%20children%27s%20personality%20and%20behavioral%20strengths%20and%20difficulties%20%28assessed%20using%20parent-reported%20questionnaires%29%20were%20estimated%20using%20multiple%20linear%20regression%20analyses.%5CnResults%5CnWith%20respect%20to%20children%27s%20personality%2C%20the%20analyses%20revealed%20significant%20positive%20associations%20between%20speaking-voice%20intensity%20and%20extraversion%20%28eg%2C%20for%20the%20conversational%20voice%2C%20%5Cu03b2%5Cu202f%3D%5Cu202f0.16%2C%20P%20%3C%200.001%29%20as%20well%20as%20significant%20negative%20associations%20between%20voice%20intensity%20and%20emotional%20stability%20%28eg%2C%20for%20the%20shouting%20voice%2C%20%5Cu03b2%5Cu202f%3D%5Cu202f%5Cu22120.15%2C%20P%20%3D%200.004%29%20and%20conscientiousness%20%28for%20the%20shouting%20voice%2C%20%5Cu03b2%20%3D%20%5Cu22120.10%2C%20P%5Cu202f%3D%5Cu202f0.033%29.%20Regarding%20behavioral%20strengths%20and%20difficulties%2C%20we%20observed%20significant%20positive%20associations%20between%20voice%20intensity%20and%20peer-relationship%20problems%20%28eg%2C%20for%20the%20conversational%20voice%2C%20%5Cu03b2%5Cu202f%3D%5Cu202f0.14%2C%20P%5Cu202f%3D%5Cu202f0.001%29%20and%20prosocial%20behavior%20%28for%20the%20conversational%20voice%2C%20%5Cu03b2%5Cu202f%3D%5Cu202f0.11%2C%20P%5Cu202f%3D%5Cu202f0.015%29.%20In%20contrast%2C%20no%20significant%20association%20was%20found%20between%20speaking%20fundamental%20frequency%20and%20personality%20or%20behavioral%20difficulties%5C%2Fstrengths.%5CnConclusions%5CnIn%20children%2C%20associations%20exist%20between%20a%20child%27s%20speaking-voice%20intensity%20and%20his%20or%20her%20personality%2C%20especially%20extraversion%20and%20emotional%20stability%2C%20and%20behavioral%20characteristics.%22%2C%22date%22%3A%22October%2C%202018%22%2C%22language%22%3A%22%22%2C%22DOI%22%3A%2210.1016%5C%2Fj.jvoice.2018.09.022%22%2C%22ISSN%22%3A%220892-1997%22%2C%22url%22%3A%22http%3A%5C%2F%5C%2Fwww.sciencedirect.com%5C%2Fscience%5C%2Farticle%5C%2Fpii%5C%2FS089219971830345X%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-27T08%3A47%3A05Z%22%7D%7D%2C%7B%22key%22%3A%22KCY7IZX4%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Poulain%20et%20al.%22%2C%22parsedDate%22%3A%222017-01%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EPoulain%2C%20Tanja%2C%20Ronny%20Baber%2C%20Mandy%20Vogel%2C%20Diana%20Pietzner%2C%20Toralf%20Kirsten%2C%20Anne%20Jurkutat%2C%20Andreas%20Hiemisch%2C%20et%20al.%20%26%23x201C%3BThe%20Life%20Child%20Study%3A%20A%20Population-Based%20Perinatal%20and%20Pediatric%20Cohort%20in%20Germany.%26%23x201D%3B%20%3Ci%3EEuropean%20Journal%20of%20Epidemiology%3C%5C%2Fi%3E%2032%2C%20no.%202%20%28January%202017%29%3A%20145%26%23×2013%3B58.%20%3Ca%20class%3D%27zp-ItemURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs10654-016-0216-9%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs10654-016-0216-9%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22The%20Life%20Child%20Study%3A%20A%20Population-Based%20Perinatal%20and%20Pediatric%20Cohort%20in%20Germany%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ronny%22%2C%22lastName%22%3A%22Baber%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Diana%22%2C%22lastName%22%3A%22Pietzner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Toralf%22%2C%22lastName%22%3A%22Kirsten%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anne%22%2C%22lastName%22%3A%22Jurkutat%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andreas%22%2C%22lastName%22%3A%22Hiemisch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anja%22%2C%22lastName%22%3A%22Hilbert%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J%5Cu00fcrgen%22%2C%22lastName%22%3A%22Kratzsch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Joachim%22%2C%22lastName%22%3A%22Thiery%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Michael%22%2C%22lastName%22%3A%22Fuchs%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christian%22%2C%22lastName%22%3A%22Hirsch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Franziska%20G.%22%2C%22lastName%22%3A%22Rauscher%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Markus%22%2C%22lastName%22%3A%22Loeffler%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Matthias%22%2C%22lastName%22%3A%22N%5Cu00fcchter%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22name%22%3A%22LIFE%20Child%20study%20team%22%7D%5D%2C%22abstractNote%22%3A%22The%20LIFE%20Child%20study%20is%20a%20large%20population-based%20longitudinal%20childhood%20cohort%20study%20conducted%20in%20the%20city%20of%20Leipzig%2C%20Germany.%20As%20a%20part%20of%20LIFE%2C%20a%20research%20project%20conducted%20at%20the%20Leipzig%20Research%20Center%20for%20Civilization%20Diseases%2C%20it%20aims%20to%20monitor%20healthy%20child%20development%20from%20birth%20to%20adulthood%20and%20to%20understand%20the%20development%20of%20lifestyle%20diseases%20such%20as%20obesity.%20The%20study%20consists%20of%20three%20interrelated%20cohorts%3B%20the%20birth%20cohort%2C%20the%20health%20cohort%2C%20and%20the%20obesity%20cohort.%20Depending%20on%20age%20and%20cohort%2C%20the%20comprehensive%20study%20program%20comprises%20different%20medical%2C%20psychological%2C%20and%20sociodemographic%20assessments%20as%20well%20as%20the%20collection%20of%20biological%20samples.%20Optimal%20data%20acquisition%2C%20process%20management%2C%20and%20data%20analysis%20are%20guaranteed%20by%20a%20professional%20team%20of%20physicians%2C%20certified%20study%20assistants%2C%20quality%20managers%2C%20scientists%20and%20statisticians.%20Due%20to%20the%20high%20popularity%20of%20the%20study%2C%20more%20than%203000%20children%20have%20already%20participated%20until%20the%20end%20of%202015%2C%20and%20two-thirds%20of%20them%20participate%20continuously.%20The%20large%20quantity%20of%20acquired%20data%20allows%20LIFE%20Child%20to%20gain%20profound%20knowledge%20on%20the%20development%20of%20children%20growing%20up%20in%20the%20twenty-first%20century.%20This%20article%20reports%20the%20number%20of%20available%20and%20analyzable%20data%20and%20demonstrates%20the%20high%20relevance%20and%20potential%20of%20the%20study.%22%2C%22date%22%3A%22January%2C%202017%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1007%5C%2Fs10654-016-0216-9%22%2C%22ISSN%22%3A%221573-7284%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs10654-016-0216-9%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-12-28T13%3A15%3A46Z%22%7D%7D%5D%7D
Dienerowitz, Tobias, Thomas Peschel, Mandy Vogel, Tanja Poulain, Christoph Engel, Wieland Kiess, Michael Fuchs, and Thomas Berger. “Establishing Normative Data on Singing Voice Parameters of Children and Adolescents with Average Singing Activity Using the Voice Range Profile.” Folia Phoniatrica et Logopaedica: Official Organ of the International Association of Logopedics and Phoniatrics (IALP) 73, no. 6 (December 2021). https://doi.org/10.1159/000513521.
Berger, Thomas, Sylvia Meuret, Christoph Engel, Mandy Vogel, Wieland Kiess, Michael Fuchs, and Tanja Poulain. “[Detection of Relevant Changes in the Speaking Voice of Women Measured by the Speaking Voice Profile].” Laryngo- Rhino- Otologie, December 2020. https://doi.org/10.1055/a-1327-4275.
Berger, Thomas, Thomas Peschel, Mandy Vogel, Diana Pietzner, Tanja Poulain, Anne Jurkutat, Sylvia Meuret, Christoph Engel, Wieland Kiess, and Michael Fuchs. “Speaking Voice in Children and Adolescents: Normative Data and Associations with Bmi, Tanner Stage, and Singing Activity.” Journal of Voice 33, no. 4 (July 2019): 580.e21-580.e30. https://doi.org/10.1016/j.jvoice.2018.01.006.
Poulain, Tanja, Michael Fuchs, Mandy Vogel, Anne Jurkutat, Andreas Hiemisch, Wieland Kiess, and Thomas Berger. “Associations of Speaking-Voice Parameters with Personality and Behavior in School-Aged Children.” Journal of Voice online ahead of print, no. 34 (October 2018): 3. https://doi.org/10.1016/j.jvoice.2018.09.022.
Poulain, Tanja, Ronny Baber, Mandy Vogel, Diana Pietzner, Toralf Kirsten, Anne Jurkutat, Andreas Hiemisch, et al. “The Life Child Study: A Population-Based Perinatal and Pediatric Cohort in Germany.” European Journal of Epidemiology 32, no. 2 (January 2017): 145–58. https://doi.org/10.1007/s10654-016-0216-9.
2390247
T52N9QLZ
pregnancy
1
chicago-fullnote-bibliography
50
date
desc
1
1
6748
https://home.uni-leipzig.de/lifechild/wp-content/plugins/zotpress/
%7B%22status%22%3A%22success%22%2C%22updateneeded%22%3Afalse%2C%22instance%22%3Afalse%2C%22meta%22%3A%7B%22request_last%22%3A0%2C%22request_next%22%3A0%2C%22used_cache%22%3Atrue%7D%2C%22data%22%3A%5B%7B%22key%22%3A%22EB3A53J6%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Barzen%20et%20al.%22%2C%22parsedDate%22%3A%222024-04-13%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EBarzen%2C%20Charlotte%2C%20Mandy%20Vogel%2C%20Wieland%20Kiess%2C%20and%20Tanja%20Poulain.%20%26%23x201C%3BAssociations%20between%20Gestational%20Weight%20Gain%20and%20Weight%20Development%20of%20the%20Offspring%3A%20Differences%20Depending%20on%20Maternal%20Pre-Pregnancy%20BMI.%26%23x201D%3B%20%3Ci%3EArchives%20of%20Gynecology%20and%20Obstetrics%3C%5C%2Fi%3E%2C%20April%2013%2C%202024.%20%3Ca%20class%3D%27zp-ItemURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs00404-024-07487-1%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs00404-024-07487-1%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Associations%20between%20gestational%20weight%20gain%20and%20weight%20development%20of%20the%20offspring%3A%20Differences%20depending%20on%20maternal%20pre-pregnancy%20BMI%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Charlotte%22%2C%22lastName%22%3A%22Barzen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%5D%2C%22abstractNote%22%3A%22Obesity%20rates%20are%20rising%2C%20and%20the%20gestational%20weight%20gain%20%28GWG%29%20of%20most%20women%20does%20not%20comply%20with%20current%20guidelines.%20This%20study%20assesses%20the%20association%20of%20pre-pregnancy%20BMI%20%28ppBMI%29%20and%20GWG%20with%20the%20child%5Cu2019s%20weight%20development%20and%20investigates%20whether%20associations%20with%20GWG%20differ%20depending%20on%20ppBMI.%22%2C%22date%22%3A%222024-04-13%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1007%5C%2Fs00404-024-07487-1%22%2C%22ISSN%22%3A%221432-0711%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs00404-024-07487-1%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222024-04-15T06%3A03%3A53Z%22%7D%7D%2C%7B%22key%22%3A%2298ACU36I%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Dathan-Stumpf%20et%20al.%22%2C%22parsedDate%22%3A%222023-03-02%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EDathan-Stumpf%2C%20Anne%2C%20Mandy%20Vogel%2C%20Nico%20Grafe%2C%20Wieland%20Kiess%2C%20and%20Holger%20Stepan.%20%26%23x201C%3BRelation%20between%20Socioeconomic%20Status%20and%20Maternal%20Serum%20Lipids%20to%20Infant%20Lipid%20Concentrations%20and%20Anthropometry%20in%20the%20First%20Year%20of%20Life.%26%23x201D%3B%20%3Ci%3EArchives%20of%20Gynecology%20and%20Obstetrics%3C%5C%2Fi%3E%2C%20March%202%2C%202023.%20%3Ca%20class%3D%27zp-ItemURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs00404-023-06937-6%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs00404-023-06937-6%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Relation%20between%20socioeconomic%20status%20and%20maternal%20serum%20lipids%20to%20infant%20lipid%20concentrations%20and%20anthropometry%20in%20the%20first%20year%20of%20life%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anne%22%2C%22lastName%22%3A%22Dathan-Stumpf%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Nico%22%2C%22lastName%22%3A%22Grafe%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Holger%22%2C%22lastName%22%3A%22Stepan%22%7D%5D%2C%22abstractNote%22%3A%22The%20physical%20health%20and%20development%20of%20an%20individual%20are%20influenced%20by%20multiple%20parameters%20and%20shaped%20by%20internal%20and%20external%20factors%20during%20pregnancy.%20However%2C%20it%20is%20unclear%20whether%20there%20is%20an%20association%20between%20maternal%20lipid%20concentrations%20in%20the%20third%20trimester%20of%20pregnancy%20and%20infant%20serum%20lipids%20as%20well%20as%20anthropometric%20growth%2C%20and%20whether%20these%20factors%20are%20influenced%20by%20the%20socioeconomic%20status%20%28SES%29%20of%20the%20mothers.%22%2C%22date%22%3A%222023-03-02%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1007%5C%2Fs00404-023-06937-6%22%2C%22ISSN%22%3A%221432-0711%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs00404-023-06937-6%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-23T12%3A21%3A59Z%22%7D%7D%2C%7B%22key%22%3A%22SAGIDNQR%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Poulain%20et%20al.%22%2C%22parsedDate%22%3A%222021-09%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EPoulain%2C%20Tanja%2C%20Ulrike%20Spielau%2C%20Mandy%20Vogel%2C%20Anne%20Dathan-Stumpf%2C%20Antje%20K%26%23xF6%3Brner%2C%20and%20Wieland%20Kiess.%20%26%23x201C%3BChanges%20in%20Diet%20from%20Pregnancy%20to%20One%20Year%20After%20Birth%3A%20A%20Longitudinal%20Study.%26%23x201D%3B%20%3Ci%3EBMC%20Pregnancy%20and%20Childbirth%3C%5C%2Fi%3E%2021%2C%20no.%201%20%28September%202021%29%3A%20600.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs12884-021-04038-3%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs12884-021-04038-3%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Changes%20in%20Diet%20from%20Pregnancy%20to%20One%20Year%20After%20Birth%3A%20A%20Longitudinal%20Study%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ulrike%22%2C%22lastName%22%3A%22Spielau%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anne%22%2C%22lastName%22%3A%22Dathan-Stumpf%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%5D%2C%22abstractNote%22%3A%22BACKGROUND%3A%20Pregnancy%20and%20the%20first%20year%20after%20giving%20birth%20are%20marked%20by%20physiological%20and%20psychological%20changes.%20While%20it%20is%20well%20known%20that%20energy%20requirements%20change%20during%20this%20time%2C%20the%20question%20of%20how%20a%20woman%27s%20diet%20actually%20changes%20from%20pregnancy%20until%201%5Cu00a0year%20postpartum%20has%20been%20left%20virtually%20unexplored.%20The%20present%20study%20employs%20a%20longitudinal%20design%20to%20investigate%20these%20changes.%5CnMETHODS%3A%20Data%20were%20collected%20within%20the%20framework%20of%20the%20LIFE%20Child%20study%20%28Leipzig%2C%20Germany%29.%20The%20diet%20composition%20and%20culture%20of%20eating%20of%20110%20women%20were%20assessed%20at%203%20time%20points%3A%20in%20the%2024th%20week%20of%20pregnancy%2C%203%5Cu2009months%20after%20giving%20birth%20%28breastfeeding%20period%29%2C%20and%2012%5Cu2009months%20after%20giving%20birth%20%28after%20weaning%29.%20We%20assessed%20differences%20in%20nutritional%20health%20%28Nutritional%20Health%20Score%2C%20NHS%29%20and%20the%20consumption%20of%20different%20food%20items%20at%20each%20of%20these%20time%20points.%20We%20also%20investigated%20associations%20between%20nutritional%20health%20and%20age%2C%20socio-economic%20status%20%28SES%29%2C%20BMI%20before%20pregnancy%2C%20and%20previous%20births%20at%20all%20three%20time%20points.%5CnRESULTS%3A%20The%20analyses%20revealed%20high%20correlations%20in%20the%20NHS%20values%20between%20the%20three%20time%20points%20%28rhot0%5C%2Ft1%5Cu2009%3D%5Cu2009.55%2C%20rhot0%5C%2Ft2%5Cu2009%3D%5Cu2009.60%29.%20On%20average%2C%20nutritional%20health%20was%20lower%20in%20the%20breastfeeding%20period%20than%20during%20pregnancy.%20In%20more%20detail%2C%20women%20reported%20less%20healthy%20levels%20of%20treats%20and%20white%20bread%20consumption%20and%20a%20higher%20frequency%20of%20snacking%20in%20the%20breastfeeding%20period%20than%20during%20pregnancy.%20In%20contrast%2C%20overall%20nutritional%20health%20did%20not%20differ%20significantly%20between%20pregnancy%20and%20the%20time%20after%20weaning.%20Increased%20age%20was%20associated%20with%20a%20healthier%20diet%20during%20pregnancy%2C%20and%20a%20high%20SES%20was%20associated%20with%20healthier%20diet%20after%20weaning.%20Furthermore%2C%20the%20increase%20in%20nutritional%20health%20from%20the%20breastfeeding%20period%20to%20the%20time%20after%20weaning%20was%20significantly%20stronger%20in%20women%20with%20a%20higher%20BMI.%20We%20observed%20no%20significant%20associations%20between%20dietary%20nutritional%20health%20and%20previous%20births.%5CnCONCLUSIONS%3A%20The%20present%20findings%20suggest%20that%20higher%20energy%20requirements%20in%20the%20breastfeeding%20period%20are%20met%20by%20consuming%20high-calorie%20and%20unhealthy%20food%20products%20rather%20than%20healthy%20and%20nutrient-rich%20food.%20Young%20mothers%20should%20be%20supported%20in%20taking%20care%20of%20their%20own%20nutritional%20health%20during%20the%20challenging%20time%20of%20breastfeeding%20and%20caring%20for%20a%20newborn%20child.%22%2C%22date%22%3A%222021-09%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1186%5C%2Fs12884-021-04038-3%22%2C%22ISSN%22%3A%221471-2393%22%2C%22url%22%3A%22http%3A%5C%2F%5C%2Forgid.org%5C%2F10.1186%5C%2Fs12884-021-04038-3%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-07T07%3A01%3A32Z%22%7D%7D%2C%7B%22key%22%3A%22H3XTUW3C%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Eichler%20et%20al.%22%2C%22parsedDate%22%3A%222021-09%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EEichler%2C%20Janina%2C%20Ricarda%20Schmidt%2C%20Tanja%20Poulain%2C%20Andreas%20Hiemisch%2C%20Wieland%20Kiess%2C%20and%20Anja%20Hilbert.%20%26%23x201C%3BMaternal%20Depressive%20Symptoms%20and%20Stress%20During%20Pregnancy%20as%20Predictors%20of%20Gestational%20Age%20at%20Birth%20and%20Standardized%20Body%20Mass%20Index%20from%20Birth%20up%20to%202%20Years%20of%20Age.%26%23x201D%3B%20%3Ci%3EBMC%20Pregnancy%20and%20Childbirth%3C%5C%2Fi%3E%2021%2C%20no.%201%20%28September%202021%29%3A%20635.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs12884-021-04111-x%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs12884-021-04111-x%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Maternal%20Depressive%20Symptoms%20and%20Stress%20During%20Pregnancy%20as%20Predictors%20of%20Gestational%20Age%20at%20Birth%20and%20Standardized%20Body%20Mass%20Index%20from%20Birth%20up%20to%202%20Years%20of%20Age%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Janina%22%2C%22lastName%22%3A%22Eichler%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ricarda%22%2C%22lastName%22%3A%22Schmidt%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andreas%22%2C%22lastName%22%3A%22Hiemisch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anja%22%2C%22lastName%22%3A%22Hilbert%22%7D%5D%2C%22abstractNote%22%3A%22BACKGROUND%3A%20While%20depressive%20symptoms%20and%20stress%20during%20pregnancy%20are%20known%20to%20affect%20gestational%20age%20and%20weight%20at%20birth%2C%20evidence%20on%20their%20impact%20on%20child%20anthropometric%20development%20in%20the%20long%20term%20remains%20limited%2C%20showing%20inconsistent%20effects.%20Importantly%2C%20previous%20research%20indicated%20a%20substantially%20stronger%20impact%20of%20categorically%20rather%20than%20dimensionally%20assessed%20mental%20health%20problems%20on%20birth%20outcomes%20and%20child%20development.%5CnMETHODS%3A%20The%20Patient%20Health%20Questionnaire%20was%20used%20to%20assess%20depressive%20symptoms%20and%20stress%20during%20the%202nd%20trimester%20of%20pregnancy%20dimensionally%20and%20categorically%2C%20with%20scores%20%5Cu226510%20indicating%20clinical%20significance.%20Gestational%20age%20at%20birth%20and%20BMI-SDS%20from%20birth%20up%20to%202%5Cu2009years%20of%20age%20were%20examined%20as%20dependent%20variables.%20Structural%20equation%20modeling%20was%20used%20to%20examine%20the%20prediction%20of%20birth%20outcomes%20and%20child%20anthropometry%20by%20mental%20health%20problems%20while%20controlling%20for%20multiple%20maternal%20and%20child%20characteristics%20in%20322%20mother-child%20dyads.%5CnRESULTS%3A%20Dimensionally%20assessed%20mental%20health%20problems%20did%20not%20significantly%20predict%20birth%20outcomes.%20While%20categorical%20depressive%20symptoms%20significantly%20predicted%20a%20higher%20child%20BMI-SDS%2C%20categorical%20stress%20significantly%20predicted%20a%20lower%20gestational%20age%20at%20birth.%20Neither%20categorical%20nor%20dimensional%20mental%20health%20problems%20significantly%20predicted%20child%20BMI-SDS%20at%206%2C%2012%2C%20and%2024%5Cu2009months%20postpartum.%5CnCONCLUSIONS%3A%20Depressive%20symptoms%20and%20stress%20during%20pregnancy%20seem%20to%20differentially%20affect%20birth%20outcomes%2C%20and%20only%20if%20clinically%20relevant.%20The%20results%20implicate%20the%20importance%20to%20timely%20treat%20pregnant%20women%20that%20are%20greatly%20affected%20by%20mental%20health%20problems%20to%20potentially%20reduce%20adverse%20birth%20outcomes.%22%2C%22date%22%3A%222021-09%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1186%5C%2Fs12884-021-04111-x%22%2C%22ISSN%22%3A%221471-2393%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Forgid.org%5C%2F10.1186%5C%2Fs12884-021-04111-x%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-23T13%3A48%3A41Z%22%7D%7D%2C%7B%22key%22%3A%229WJNQPH9%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Poulain%20et%20al.%22%2C%22parsedDate%22%3A%222020-12%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EPoulain%2C%20Tanja%2C%20Juliane%20Ludwig%2C%20Mandy%20Vogel%2C%20Andreas%20Hiemisch%2C%20Antje%20K%26%23xF6%3Brner%2C%20and%20Wieland%20Kiess.%20%26%23x201C%3B%5BThe%20LIFE%20Child%20study%3A%20A%20cohort%20study%20investigating%20child%20development%20in%20changing%20environmental%20conditions%5D.%26%23x201D%3B%20%3Ci%3EZeitschrift%20Fur%20Psychosomatische%20Medizin%20Und%20Psychotherapie%3C%5C%2Fi%3E%2066%2C%20no.%204%20%28December%202020%29%3A%20390%26%23×2013%3B401.%20%3Ca%20class%3D%27zp-ItemURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.13109%5C%2Fzptm.2020.66.4.390%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.13109%5C%2Fzptm.2020.66.4.390%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22%5BThe%20LIFE%20Child%20study%3A%20A%20cohort%20study%20investigating%20child%20development%20in%20changing%20environmental%20conditions%5D%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Juliane%22%2C%22lastName%22%3A%22Ludwig%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andreas%22%2C%22lastName%22%3A%22Hiemisch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%5D%2C%22abstractNote%22%3A%22The%20LIFE%20Child%20study%3A%20A%20cohort%20study%20investigating%20child%20development%20in%20changing%20environmental%20conditionsObjectives%3A%20The%20LIFE%20Child%20study%20investigates%20healthy%20child%20development%20from%20pregnancy%20to%20young%20adulthood%20and%20the%20development%20of%20lifestyle%20diseases.%20Methods%3A%20Since%20study%20initiation%20in%202011%2C%201068%20pregnant%20women%20and%204658%20children%20have%20been%20included%20in%20the%20study.%20Children%20are%20recruited%20until%20the%20age%20of%2016%20years.%20Follow-up%20visits%20take%20place%20once%20per%20year.%20Assessments%20include%20physical%20examinations%2C%20interviews%2C%20questionnaires%2C%20standardized%20tests%2C%20and%20biological%20samples%20including%20genetic%20analysis.%20Results%3A%20We%20found%20significant%20associations%20between%20socio-economic%20status%20and%20health%20behaviour%2C%20between%20the%20weight%20of%20mothers%20and%20their%20children%20and%20between%20excessive%20media%20use%20and%20psychological%20complaints.%20Further%20projects%20dealt%20with%20the%20creation%20of%20references%20curves%20and%20the%20evaluation%20of%20new%20research%20methods.%20Conclusions%3A%20The%20study%20provides%20important%20insights%20into%20the%20interplay%20between%20the%20living%20environment%2C%20behaviour%20and%20child%20health.%22%2C%22date%22%3A%222020-12%22%2C%22language%22%3A%22ger%22%2C%22DOI%22%3A%2210.13109%5C%2Fzptm.2020.66.4.390%22%2C%22ISSN%22%3A%221438-3608%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.13109%5C%2Fzptm.2020.66.4.390%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-23T10%3A11%3A51Z%22%7D%7D%2C%7B%22key%22%3A%22XMIA36N3%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Schreiter%20et%20al.%22%2C%22parsedDate%22%3A%222019-09%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3ESchreiter%2C%20Juliane%2C%20Mandy%20Vogel%2C%20Henriette%20Kiep%2C%20Ulrich%20Thome%2C%20Annett%20Bl%26%23xE4%3Bser%2C%20Petra%20Nickel%2C%20Wieland%20Kiess%2C%20and%20Matthias%20K.%20Bernhard.%20%26%23x201C%3B%5BThe%20Cognitive%2C%20Language%20and%20Motor%20Development%20of%20Prenatal%20Methamphetamine-%20and%20Opioid-exposed%20Children%5D.%26%23x201D%3B%20%3Ci%3EKlinische%20Padiatrie%3C%5C%2Fi%3E%20231%2C%20no.%205%20%28September%202019%29%3A%20262%26%23×2013%3B68.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1055%5C%2Fa-0981-6322%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1055%5C%2Fa-0981-6322%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22%5BThe%20Cognitive%2C%20Language%20and%20Motor%20Development%20of%20Prenatal%20Methamphetamine-%20and%20Opioid-exposed%20Children%5D%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Juliane%22%2C%22lastName%22%3A%22Schreiter%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Henriette%22%2C%22lastName%22%3A%22Kiep%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ulrich%22%2C%22lastName%22%3A%22Thome%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Annett%22%2C%22lastName%22%3A%22Bl%5Cu00e4ser%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Petra%22%2C%22lastName%22%3A%22Nickel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Matthias%20K.%22%2C%22lastName%22%3A%22Bernhard%22%7D%5D%2C%22abstractNote%22%3A%22OBJECTIVE%3A%20The%20consumption%20of%20illegal%20substances%20during%20pregnancy%20is%20an%20increasing%20social%20and%20medical%20issue.%20Main%20substances%20of%20prenatal%20drug%20exposure%20are%20beside%20tehtrahydrocannabinol%20%28THC%29%2C%20opioids%20and%20methamphetamine.%20The%20effect%20of%20these%20substances%20on%20the%20long-term%20development%20of%20children%20remains%20uncertain.%5CnMETHODS%3A%20Since%202012%20newborn%20infants%20born%20at%20the%20university%20hospital%20of%20children%20at%20Leipzig%20which%20were%20prenatal%20exposed%20to%20drugs%20were%20followed%20long-term%20at%20the%20out-patient%20clinic%20for%20child%20protection.%20For%2042%20children%20with%20prenatal%20opioid%20or%20methamphetamine%20exposure%20the%20developmentent%20was%20analysed%20using%20the%20Bayley%20Scales%20%28BSID%20III%29%20at%20the%20age%20of%202-3%20years.%20The%20children%20were%20compared%20with%2084%20unexposed%20control%20children.%20One%20case%20matched%20to%202%20controls%2C%20adapted%20by%20age%2C%20gender%2C%20gestational%20age%20and%20birth%20weight.%5CnRESULTS%3A%20Motoric%20development%20between%20prenatal%20methylamphetamine%2C%20opioid%20exposed%20children%20and%20the%20control%20group%20showed%20no%20significant%20difference.%20Methylamphetamine%20exposed%20children%20%28n%3D23%29%20At%202%20exposure%20show%20significantly%20lower%20scores%20in%20cognition%20and%20language%20%2879%2C1%20compared%2095%2C9%20of%20the%20control%20group%29%2C%20opioid%20exposed%20children%20have%20a%20slight%20cognitive%20deficits%20with%20a%20medium%20score%20of%2091%2C7%20%28n%3D19%29.%2056%25%20of%20the%20methamphetamine%20group%20were%20developmentally%20retarded%20at%20the%20measurement%20date.%20Additionally%2C%20children%20had%20significant%20lower%20Bayley%20Scores%20which%20had%20single%20parent%20and%5C%2F%20or%20low%20educational%20and%20professional%20qualifications%20of%20their%20caregiver.%20Both%20substances%20increased%20the%20risk%20of%20postnatal%20complications%20to%2046-53%25%20despite%20of%20similar%20gestational%20ages%20in%20all%20groups.%5CnCONCLUSION%3A%20Children%20with%20prenatal%20methamphetamine%20or%20opioid%20exposure%20seem%20to%20have%20cognition%20and%20language%20deficits%20at%202%20and%203%20years%20of%20age.%20Methamphetamine%20might%20have%20a%20higher%20negative%20effect%20than%20opioids.%20The%20psychosocial%20risk%20factors%20associated%20with%20parental%20drug%20abuse%20are%20important%20for%20achieving%20age-appropriate%20development.%22%2C%22date%22%3A%22Sep%202019%22%2C%22language%22%3A%22ger%22%2C%22DOI%22%3A%2210.1055%5C%2Fa-0981-6322%22%2C%22ISSN%22%3A%221439-3824%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-27T08%3A54%3A05Z%22%7D%7D%2C%7B%22key%22%3A%22JV69ZDFD%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Eichler%20et%20al.%22%2C%22parsedDate%22%3A%222019-05%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EEichler%2C%20Janina%2C%20Ricarda%20Schmidt%2C%20Andreas%20Hiemisch%2C%20Wieland%20Kiess%2C%20and%20Anja%20Hilbert.%20%26%23x201C%3BGestational%20Weight%20Gain%2C%20Physical%20Activity%2C%20Sleep%20Problems%2C%20Substance%20Use%2C%20and%20Food%20Intake%20as%20Proximal%20Risk%20Factors%20of%20Stress%20and%20Depressive%20Symptoms%20During%20Pregnancy.%26%23x201D%3B%20%3Ci%3EBMC%20Pregnancy%20and%20Childbirth%3C%5C%2Fi%3E%2019%2C%20no.%201%20%28May%202019%29%3A%20175.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs12884-019-2328-1%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs12884-019-2328-1%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Gestational%20Weight%20Gain%2C%20Physical%20Activity%2C%20Sleep%20Problems%2C%20Substance%20Use%2C%20and%20Food%20Intake%20as%20Proximal%20Risk%20Factors%20of%20Stress%20and%20Depressive%20Symptoms%20During%20Pregnancy%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Janina%22%2C%22lastName%22%3A%22Eichler%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ricarda%22%2C%22lastName%22%3A%22Schmidt%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andreas%22%2C%22lastName%22%3A%22Hiemisch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anja%22%2C%22lastName%22%3A%22Hilbert%22%7D%5D%2C%22abstractNote%22%3A%22BACKGROUND%3A%20Because%20maternal%20depressive%20symptoms%20and%20stress%20during%20pregnancy%20are%20strongly%20associated%20with%20poor%20health%20of%20the%20mother%20and%20the%20developing%20child%2C%20understanding%20the%20predictors%20of%20women%27s%20mental%20health%20problems%20is%20important%20to%20prevent%20complications%20in%20the%20perinatal%20period.%20Therefore%2C%20this%20study%20sought%20to%20examine%20the%20association%20between%20six%20risk%20factors%20-%20gestational%20weight%20gain%20%28GWG%29%2C%20low%20physical%20activity%2C%20sleep%20problems%2C%20alcohol%20use%2C%20cigarette%20smoking%20and%20snack%20food%20intake%20-%20and%20mental%20health%20problems%20during%20pregnancy.%20We%20hypothesized%20that%20risk%20factors%20would%20predict%20mental%20health%20problems%20while%20adjusting%20for%20socio-demographic%20characteristics%20and%20pregnancy%20intention%2C%20both%20cross-sectionally%20and%20longitudinally.%5CnMETHODS%3A%20Hierarchical%20linear%20regression%20analyses%20were%20conducted%20in%20a%20population-based%20sample%20of%20N%5Cu2009%3D%5Cu2009463%20pregnant%20women%20during%20their%202nd%20trimester%20%28gestational%20age%3A%2023%20to%2028%5Cu2009weeks%29%20of%20whom%20n%5Cu2009%3D%5Cu2009349%20were%20reassessed%20during%20their%203rd%20trimester%20%28gestational%20age%3A%2033%20to%2038%5Cu2009weeks%29.%20Women%20had%20a%20mean%20age%20of%2029.8%5Cu2009%5Cu00b1%5Cu20094.2%5Cu2009years%20and%20a%20mean%20pregravid%20body%20mass%20index%20of%2023.5%5Cu2009%5Cu00b1%5Cu20094.3%5Cu2009kg%5C%2Fm2.%20Data%20were%20collected%20by%20the%20%27Leipzig%20Research%20Center%20for%20Civilization%20Diseases%27%20via%20the%20Patient%20Health%20Questionnaire%2C%20Pittsburgh%20Sleep%20Quality%20Index%2C%20Food%20Frequency%20Questionnaire%2C%20self-report%20items%20on%20physical%20activity%20and%20substance%20use%2C%20and%20objectively%20measured%20anthropometrics.%5CnRESULTS%3A%20Cross-sectionally%2C%20while%20a%20higher%20snack%20food%20intake%20and%20sleep%20problems%20predicted%20depressive%20symptoms%20and%20stress%20during%20the%202nd%20trimester%2C%20gestational%20weight%20gain%20predicted%20stress%20only.%20Longitudinally%2C%20sleep%20problems%20positively%20predicted%20depressive%20symptoms%20during%20the%203rd%20trimester.%20All%20results%20remained%20significant%20after%20controlling%20for%20age%2C%20pregravid%20body%20mass%20index%2C%20and%20pregnancy%20intention.%20GWG%20and%20significant%20longitudinal%20effects%20became%20insignificant%20when%20controlling%20for%20gestational%20age%20or%20baseline%20depressive%20symptoms%20and%20stress%2C%20respectively.%5CnCONCLUSIONS%3A%20The%20results%20showed%20that%20sleep%20problems%20were%20associated%20with%20maternal%20mental%20health%20problems%20during%20pregnancy.%20Longitudinal%20studies%20using%20standardized%20measures%2C%20particularly%20diagnostic%20interviews%20and%20physiological%20or%20biochemical%20markers%2C%20are%20warranted%20to%20confirm%20patterns%20of%20risk%20factors%2C%20their%20association%20with%20depressive%20symptoms%20and%20stress%20during%20the%20course%20of%20pregnancy%2C%20and%20their%20effects%20on%20mother%27s%20and%20child%27s%20health.%22%2C%22date%22%3A%22May%2C%202019%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1186%5C%2Fs12884-019-2328-1%22%2C%22ISSN%22%3A%221471-2393%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Forgid.org%5C%2F10.1186%5C%2Fs12884-019-2328-1%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-23T12%3A51%3A58Z%22%7D%7D%2C%7B%22key%22%3A%22YUNYIIFC%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Scharlau%20et%20al.%22%2C%22parsedDate%22%3A%222018-01%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EScharlau%2C%20Friederike%2C%20Diana%20Pietzner%2C%20Mandy%20Vogel%2C%20Alexander%20Gaudl%2C%20Uta%20Ceglarek%2C%20Joachim%20Thiery%2C%20J%26%23xFC%3Brgen%20Kratzsch%2C%20Andreas%20Hiemisch%2C%20and%20Wieland%20Kiess.%20%26%23x201C%3BEvaluation%20of%20Hair%20Cortisol%20and%20Cortisone%20Change%20During%20Pregnancy%20and%20the%20Association%20with%20Self-Reported%20Depression%2C%20Somatization%2C%20and%20Stress%20Symptoms.%26%23x201D%3B%20%3Ci%3EStress%20%28Amsterdam%2C%20Netherlands%29%3C%5C%2Fi%3E%2021%2C%20no.%201%20%28January%202018%29%3A%2043%26%23×2013%3B50.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1080%5C%2F10253890.2017.1392507%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1080%5C%2F10253890.2017.1392507%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Evaluation%20of%20Hair%20Cortisol%20and%20Cortisone%20Change%20During%20Pregnancy%20and%20the%20Association%20with%20Self-Reported%20Depression%2C%20Somatization%2C%20and%20Stress%20Symptoms%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Friederike%22%2C%22lastName%22%3A%22Scharlau%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Diana%22%2C%22lastName%22%3A%22Pietzner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Alexander%22%2C%22lastName%22%3A%22Gaudl%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Uta%22%2C%22lastName%22%3A%22Ceglarek%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Joachim%22%2C%22lastName%22%3A%22Thiery%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J%5Cu00fcrgen%22%2C%22lastName%22%3A%22Kratzsch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andreas%22%2C%22lastName%22%3A%22Hiemisch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%5D%2C%22abstractNote%22%3A%22Hair%20cortisol%20levels%20are%20used%20to%20measure%20long-term%20stress%2C%20while%20its%20inactive%20metabolite%20cortisone%20is%20often%20not%20assessed.%20We%20measured%20hair%20cortisol%20concentrations%20%28HCC%29%20and%20hair%20cortisone%20concentrations%20%28HCNC%29%20via%20liquid%20chromatography%20quadrupole%20linear%20ion%20trap%20mass%20spectrometry%20%28LC-MS3%29%20in%2062%20pregnant%20women%20who%20participated%20in%20the%20LIFE%20CHILD%20STUDY%20in%20their%202nd%20and%203rd%20trimester%20between%2012%5C%2F2011%20and%2011%5C%2F2014.%20Sociodemographic%20factors%2C%20pregnancy-related%20factors%2C%20and%20hair%20characteristics%20were%20assessed.%20Degree%20of%20severity%20of%20depression%2C%20somatization%2C%20and%20stress%20were%20evaluated%20in%20both%20trimesters%20with%20a%20self-reported%20Patient%20Health%20Questionnaire%20%28PHQ%29.%20Multivariate%20regression%20analyses%20were%20conducted%20between%20HCC%20and%20potential%20influencing%20factors%2C%20as%20well%20as%20with%20subscales%20of%20the%20PHQ%2C%20with%20HCNC%20and%20with%20the%20ratio%20of%20HCNC%20to%20HCC.%20Spearman%20correlation%20coefficients%20were%20calculated%20between%20steroid%20concentrations%20and%20subscale%20scores%20of%20the%20PHQ%2C%20as%20well%20as%20between%20the%20log2-fold%20change%20in%20HCC%20and%20HCNC%20and%20the%20change%20in%20PHQ%20subscale%20scores.%20HCC%20increased%201.3-fold%20and%20HCNC%20increased%201.5-fold%20by%20the%203rd%20trimester.%20HCNC%20was%20more%20than%20three%20times%20higher%20than%20HCC%20in%20both%20trimesters.%20We%20found%20significant%20associations%20of%20PHQ%20subscores%20with%20HCNC.%20The%20PHQ%20depression%20score%20was%20negatively%20correlated%20with%20HCNC%20in%20the%202nd%20trimester%20%28p%5Cu2009%3C%5Cu2009.05%29.%20The%20PHQ%20stress%20score%20change%20was%20negatively%20correlated%20with%20the%20fold%20change%20of%20HCNC%20%28p%5Cu2009%3C%5Cu2009.05%29%20and%20with%20the%20change%20in%20the%20ratio%20of%20HCNC%20to%20HCC%20%28p%5Cu2009%3C%5Cu2009.001%29.%20Our%20study%20suggests%20an%20association%20of%20cortisol%5C%2Fcortisone%20metabolism%20with%20self-reported%20stress%20in%20the%202nd%20and%203rd%20trimester%20of%20pregnancy.%20Since%20associations%20with%20PHQ%20subscores%20were%20only%20found%20with%20cortisone%20or%20the%20ratio%20of%20cortisone%20to%20cortisol%2C%20but%20not%20with%20cortisol%20alone%2C%20both%20cortisone%20and%20cortisol%20should%20be%20used%20as%20a%20marker%20for%20stress%20in%20pregnant%20woman.%22%2C%22date%22%3A%22January%202018%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1080%5C%2F10253890.2017.1392507%22%2C%22ISSN%22%3A%221607-8888%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-07T07%3A01%3A28Z%22%7D%7D%2C%7B%22key%22%3A%22TSZBSH5J%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Pfl%5Cu00fcgner%20et%20al.%22%2C%22parsedDate%22%3A%222018-01%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EPfl%26%23xFC%3Bgner%2C%20Alina%2C%20Ulrich%20Thome%2C%20Matthias%20K.%20Bernhard%2C%20Mandy%20Vogel%2C%20Annett%20Bl%26%23xE4%3Bser%2C%20Petra%20Nickel%2C%20and%20Wieland%20Kiess.%20%26%23x201C%3B%5BMethamphetamine%20Consumption%20During%20Pregnancy%20and%20its%20Effects%20on%20Neonates%5D.%26%23x201D%3B%20%3Ci%3EKlinische%20Padiatrie%3C%5C%2Fi%3E%20230%2C%20no.%201%20%28January%202018%29%3A%2031%26%23×2013%3B38.%20%3Ca%20class%3D%27zp-ItemURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1055%5C%2Fs-0043-121991%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1055%5C%2Fs-0043-121991%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22%5BMethamphetamine%20Consumption%20During%20Pregnancy%20and%20its%20Effects%20on%20Neonates%5D%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Alina%22%2C%22lastName%22%3A%22Pfl%5Cu00fcgner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ulrich%22%2C%22lastName%22%3A%22Thome%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Matthias%20K.%22%2C%22lastName%22%3A%22Bernhard%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Annett%22%2C%22lastName%22%3A%22Bl%5Cu00e4ser%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Petra%22%2C%22lastName%22%3A%22Nickel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%5D%2C%22abstractNote%22%3A%22OBJECTIVE%3A%20Methamphetamine%20%28MA%29%20has%20become%20one%20of%20the%20most%20commonly%20used%20illegal%20drugs%20during%20pregnancy.%20We%20sought%20to%20determine%20how%20MA%20abuse%20modifies%20pregnancy%20outcomes%20and%20the%20health%20of%20the%20newborn%20infants.%20Patients%20102%20newborns%20from%20mothers%20with%20antenatal%20MA%20consumption%20were%20admitted%20to%20the%20University%20Hospital%20Leipzig%20from%202004-2015.%5CnMETHODS%3A%20The%20effects%20of%20MA%20abuse%20on%20pregnancy%20outcomes%20and%20neonates%20were%20researched%20in%20a%20retrospective%20controlled%20study.%20We%20analysed%20the%20date%20of%20pregnancy%20detection%2C%20number%20of%20antenatal%20preventive%20examinations%2C%20body%20measurements%20of%20the%20neonates%2C%20duration%20of%20hospitalization%2C%20rate%20of%20preterm%20infants%2C%20congenital%20malformations%20and%20symptoms%20of%20neonatal%20abstinence%20syndrome.%5CnRESULTS%3A%20The%20majority%20of%20pregnancies%20of%20MA%20abusing%20women%20were%20diagnosed%20during%20the%202.%20trimester%20and%20they%20had%20a%20median%20of%204%20prenatal%20care%20visits.%20The%20group%20of%20MA%20exposed%20neonates%20includes%20twice%20as%20many%20preterm%20neonates%20as%20the%20control%20group%20%28MA%3A20%2C6%25%3B%20CG%3A10%2C7%25%29.%20The%20consumption%20was%20associated%20with%20intrauterine%20growth%20restriction%2C%20an%20increased%20incidence%20of%20poor%20cardio%20respiratory%20adaptation%2C%20cardiac%20defects%20and%20a%20floppy%20muscle%20tone.%20The%20median%20time%20of%20hospitalization%20was%2010d%20as%20compared%20to%20a%20control%20group%20%28CG%3A5d%29.%20Special%20care%20was%20needed%20in%2044%25%20of%20the%20neonates%20%28CG%3A0%2C98%25%29.%20The%20median%20age%20of%20primiparous%20women%20was%2022.5%20yr%20%28CG%3A30%20yr%29%2C%204.9%25%20were%20married%20%28CG%3A38%25%29.%2057%20of%20102%20women%20were%20unemployed.%5CnCONCLUSION%3A%20Because%20of%20the%20adverse%20effects%20of%20perinatal%20MA%20abuse%20a%20multidisciplinary%20team%20is%20necessary%20to%20detect%20the%20consumption%2C%20to%20alleviate%20side%20effects%20and%20to%20provide%20efficient%20medical%20care%20for%20the%20newborns.%20Psychological%20and%20social%20support%20for%20the%20families%20are%20also%20important.%22%2C%22date%22%3A%222018-01%22%2C%22language%22%3A%22ger%22%2C%22DOI%22%3A%2210.1055%5C%2Fs-0043-121991%22%2C%22ISSN%22%3A%221439-3824%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1055%5C%2Fs-0043-121991%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-07T07%3A01%3A35Z%22%7D%7D%2C%7B%22key%22%3A%22KCY7IZX4%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Poulain%20et%20al.%22%2C%22parsedDate%22%3A%222017-01%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EPoulain%2C%20Tanja%2C%20Ronny%20Baber%2C%20Mandy%20Vogel%2C%20Diana%20Pietzner%2C%20Toralf%20Kirsten%2C%20Anne%20Jurkutat%2C%20Andreas%20Hiemisch%2C%20et%20al.%20%26%23x201C%3BThe%20Life%20Child%20Study%3A%20A%20Population-Based%20Perinatal%20and%20Pediatric%20Cohort%20in%20Germany.%26%23x201D%3B%20%3Ci%3EEuropean%20Journal%20of%20Epidemiology%3C%5C%2Fi%3E%2032%2C%20no.%202%20%28January%202017%29%3A%20145%26%23×2013%3B58.%20%3Ca%20class%3D%27zp-ItemURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs10654-016-0216-9%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs10654-016-0216-9%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22The%20Life%20Child%20Study%3A%20A%20Population-Based%20Perinatal%20and%20Pediatric%20Cohort%20in%20Germany%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ronny%22%2C%22lastName%22%3A%22Baber%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Diana%22%2C%22lastName%22%3A%22Pietzner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Toralf%22%2C%22lastName%22%3A%22Kirsten%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anne%22%2C%22lastName%22%3A%22Jurkutat%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andreas%22%2C%22lastName%22%3A%22Hiemisch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anja%22%2C%22lastName%22%3A%22Hilbert%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J%5Cu00fcrgen%22%2C%22lastName%22%3A%22Kratzsch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Joachim%22%2C%22lastName%22%3A%22Thiery%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Michael%22%2C%22lastName%22%3A%22Fuchs%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christian%22%2C%22lastName%22%3A%22Hirsch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Franziska%20G.%22%2C%22lastName%22%3A%22Rauscher%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Markus%22%2C%22lastName%22%3A%22Loeffler%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Matthias%22%2C%22lastName%22%3A%22N%5Cu00fcchter%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22name%22%3A%22LIFE%20Child%20study%20team%22%7D%5D%2C%22abstractNote%22%3A%22The%20LIFE%20Child%20study%20is%20a%20large%20population-based%20longitudinal%20childhood%20cohort%20study%20conducted%20in%20the%20city%20of%20Leipzig%2C%20Germany.%20As%20a%20part%20of%20LIFE%2C%20a%20research%20project%20conducted%20at%20the%20Leipzig%20Research%20Center%20for%20Civilization%20Diseases%2C%20it%20aims%20to%20monitor%20healthy%20child%20development%20from%20birth%20to%20adulthood%20and%20to%20understand%20the%20development%20of%20lifestyle%20diseases%20such%20as%20obesity.%20The%20study%20consists%20of%20three%20interrelated%20cohorts%3B%20the%20birth%20cohort%2C%20the%20health%20cohort%2C%20and%20the%20obesity%20cohort.%20Depending%20on%20age%20and%20cohort%2C%20the%20comprehensive%20study%20program%20comprises%20different%20medical%2C%20psychological%2C%20and%20sociodemographic%20assessments%20as%20well%20as%20the%20collection%20of%20biological%20samples.%20Optimal%20data%20acquisition%2C%20process%20management%2C%20and%20data%20analysis%20are%20guaranteed%20by%20a%20professional%20team%20of%20physicians%2C%20certified%20study%20assistants%2C%20quality%20managers%2C%20scientists%20and%20statisticians.%20Due%20to%20the%20high%20popularity%20of%20the%20study%2C%20more%20than%203000%20children%20have%20already%20participated%20until%20the%20end%20of%202015%2C%20and%20two-thirds%20of%20them%20participate%20continuously.%20The%20large%20quantity%20of%20acquired%20data%20allows%20LIFE%20Child%20to%20gain%20profound%20knowledge%20on%20the%20development%20of%20children%20growing%20up%20in%20the%20twenty-first%20century.%20This%20article%20reports%20the%20number%20of%20available%20and%20analyzable%20data%20and%20demonstrates%20the%20high%20relevance%20and%20potential%20of%20the%20study.%22%2C%22date%22%3A%22January%2C%202017%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1007%5C%2Fs10654-016-0216-9%22%2C%22ISSN%22%3A%221573-7284%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs10654-016-0216-9%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-12-28T13%3A15%3A46Z%22%7D%7D%2C%7B%22key%22%3A%22FEPG76A9%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Larsen%20et%20al.%22%2C%22parsedDate%22%3A%222013-07%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3ELarsen%2C%20Pernille%20Stemann%2C%20Mads%20Kamper-J%26%23xF8%3Brgensen%2C%20Ashley%20Adamson%2C%20Henrique%20Barros%2C%20Jens%20Peter%20Bonde%2C%20Sonia%20Brescianini%2C%20Sinead%20Brophy%2C%20et%20al.%20%26%23x201C%3BPregnancy%20and%20Birth%20Cohort%20Resources%20in%20Europe%3A%20A%20Large%20Opportunity%20for%20Aetiological%20Child%20Health%20Research.%26%23x201D%3B%20%3Ci%3EPaediatric%20and%20Perinatal%20Epidemiology%3C%5C%2Fi%3E%2027%2C%20no.%204%20%28July%202013%29%3A%20393%26%23×2013%3B414.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fppe.12060%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1111%5C%2Fppe.12060%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Pregnancy%20and%20Birth%20Cohort%20Resources%20in%20Europe%3A%20a%20Large%20Opportunity%20for%20Aetiological%20Child%20Health%20Research%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Pernille%20Stemann%22%2C%22lastName%22%3A%22Larsen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mads%22%2C%22lastName%22%3A%22Kamper-J%5Cu00f8rgensen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ashley%22%2C%22lastName%22%3A%22Adamson%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Henrique%22%2C%22lastName%22%3A%22Barros%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jens%20Peter%22%2C%22lastName%22%3A%22Bonde%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Sonia%22%2C%22lastName%22%3A%22Brescianini%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Sinead%22%2C%22lastName%22%3A%22Brophy%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Maribel%22%2C%22lastName%22%3A%22Casas%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Graham%22%2C%22lastName%22%3A%22Devereux%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Merete%22%2C%22lastName%22%3A%22Eggesb%5Cu00f8%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Maria%20Pia%22%2C%22lastName%22%3A%22Fantini%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Urs%22%2C%22lastName%22%3A%22Frey%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ulrike%22%2C%22lastName%22%3A%22Gehring%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Regina%22%2C%22lastName%22%3A%22Grazuleviciene%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tine%20Brink%22%2C%22lastName%22%3A%22Henriksen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Irva%22%2C%22lastName%22%3A%22Hertz-Picciotto%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Barbara%22%2C%22lastName%22%3A%22Heude%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Daniel%20O.%22%2C%22lastName%22%3A%22Hryhorczuk%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Hazel%22%2C%22lastName%22%3A%22Inskip%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Vincent%20W.V.%22%2C%22lastName%22%3A%22Jaddoe%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Debbie%20A%22%2C%22lastName%22%3A%22Lawlor%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Johnny%22%2C%22lastName%22%3A%22Ludvigsson%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Cecily%22%2C%22lastName%22%3A%22Kelleher%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Berthold%22%2C%22lastName%22%3A%22Koletzko%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Claudia%20Elisabeth%22%2C%22lastName%22%3A%22Kuehni%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Inger%22%2C%22lastName%22%3A%22Kull%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Henriette%20Boye%22%2C%22lastName%22%3A%22Kyhl%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Per%22%2C%22lastName%22%3A%22Magnus%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Isabelle%22%2C%22lastName%22%3A%22Momas%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Dierdre%22%2C%22lastName%22%3A%22Murray%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Juha%22%2C%22lastName%22%3A%22Pekkanen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Kinga%22%2C%22lastName%22%3A%22Polanska%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Daniela%22%2C%22lastName%22%3A%22Porta%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Gry%22%2C%22lastName%22%3A%22Poulsen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Lorenzo%22%2C%22lastName%22%3A%22Richiardi%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Nel%22%2C%22lastName%22%3A%22Roeleveld%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anne%20Mette%22%2C%22lastName%22%3A%22Skovgaard%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Radim%20J.%22%2C%22lastName%22%3A%22Sram%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Katrine%22%2C%22lastName%22%3A%22Strandberg-Larsen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Carel%22%2C%22lastName%22%3A%22Thijs%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Manon%22%2C%22lastName%22%3A%22Van%20Eijsden%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22John%22%2C%22lastName%22%3A%22Wright%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Martine%22%2C%22lastName%22%3A%22Vrijheid%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anne-Marie%20Nybo%22%2C%22lastName%22%3A%22Andersen%22%7D%5D%2C%22abstractNote%22%3A%22Background%5Cn%5CnDuring%20the%20past%2025%20years%2C%20many%20pregnancy%20and%20birth%20cohorts%20have%20been%20established.%20Each%20cohort%20provides%20unique%20opportunities%20for%20examining%20associations%20of%20early-life%20exposures%20with%20child%20development%20and%20health.%20However%2C%20to%20fully%20exploit%20the%20large%20amount%20of%20available%20resources%20and%20to%20facilitate%20cross-cohort%20collaboration%2C%20it%20is%20necessary%20to%20have%20accessible%20information%20on%20each%20cohort%20and%20its%20individual%20characteristics.%20The%20aim%20of%20this%20work%20was%20to%20provide%20an%20overview%20of%20European%20pregnancy%20and%20birth%20cohorts%20registered%20in%20a%20freely%20accessible%20database%20located%20at%20http%3A%5C%2F%5C%2Fwww.birthcohorts.net.%5Cn%5Cn%5CnMethods%5Cn%5CnEuropean%20pregnancy%20and%20birth%20cohorts%20initiated%20in%201980%20or%20later%20with%20at%20least%20300%20mother%5Cu2013child%20pairs%20enrolled%20during%20pregnancy%20or%20at%20birth%2C%20and%20with%20postnatal%20data%2C%20were%20eligible%20for%20inclusion.%20Eligible%20cohorts%20were%20invited%20to%20provide%20information%20on%20the%20data%20and%20biological%20samples%20collected%2C%20as%20well%20as%20the%20timing%20of%20data%20collection.%5Cn%5Cn%5CnResults%5Cn%5CnIn%20total%2C%2070%20cohorts%20were%20identified.%20Of%20these%2C%2056%20fulfilled%20the%20inclusion%20criteria%20encompassing%20a%20total%20of%20more%20than%20500%5Cu2009000%20live-born%20European%20children.%20The%20cohorts%20represented%2019%20countries%20with%20the%20majority%20of%20cohorts%20located%20in%20Northern%20and%20Western%20Europe.%20Some%20cohorts%20were%20general%20with%20multiple%20aims%2C%20whilst%20others%20focused%20on%20specific%20health%20or%20exposure-related%20research%20questions.%5Cn%5Cn%5CnConclusion%5Cn%5CnThis%20work%20demonstrates%20a%20great%20potential%20for%20cross-cohort%20collaboration%20addressing%20important%20aspects%20of%20child%20health.%20The%20web%20site%2C%20http%3A%5C%2F%5C%2Fwww.birthcohorts.net%2C%20proved%20to%20be%20a%20useful%20tool%20for%20accessing%20information%20on%20European%20pregnancy%20and%20birth%20cohorts%20and%20their%20characteristics.%22%2C%22date%22%3A%22July%2C%202013%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1111%5C%2Fppe.12060%22%2C%22ISSN%22%3A%221365-3016%22%2C%22url%22%3A%22http%3A%5C%2F%5C%2Fonlinelibrary.wiley.com%5C%2Fdoi%5C%2F10.1111%5C%2Fppe.12060%5C%2Fabstract%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-27T08%3A16%3A49Z%22%7D%7D%2C%7B%22key%22%3A%225VYVU76M%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Quante%20et%20al.%22%2C%22parsedDate%22%3A%222012-11%22%2C%22numChildren%22%3A2%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EQuante%2C%20Mirja%2C%20Mara%20Hesse%2C%20Mirko%20D%26%23xF6%3Bhnert%2C%20Michael%20Fuchs%2C%20Christian%20Hirsch%2C%20Elena%20Sergeyev%2C%20Nora%20Casprzig%2C%20et%20al.%20%26%23x201C%3BThe%20Life%20Child%20Study%3A%20A%20Life%20Course%20Approach%20to%20Disease%20and%20Health.%26%23x201D%3B%20%3Ci%3EBMC%20Public%20Health%3C%5C%2Fi%3E%2012%2C%20no.%201%20%28November%202012%29%3A%201021.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2F1471-2458-12-1021%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2F1471-2458-12-1021%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22The%20Life%20Child%20Study%3A%20A%20Life%20Course%20Approach%20to%20Disease%20and%20Health%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mirja%22%2C%22lastName%22%3A%22Quante%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mara%22%2C%22lastName%22%3A%22Hesse%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mirko%22%2C%22lastName%22%3A%22D%5Cu00f6hnert%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Michael%22%2C%22lastName%22%3A%22Fuchs%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christian%22%2C%22lastName%22%3A%22Hirsch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Elena%22%2C%22lastName%22%3A%22Sergeyev%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Nora%22%2C%22lastName%22%3A%22Casprzig%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Geserick%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Stephanie%22%2C%22lastName%22%3A%22Naumann%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christiane%22%2C%22lastName%22%3A%22Koch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22name%22%3A%22others%22%7D%5D%2C%22abstractNote%22%3A%22%3Cb%3EBackground%3A%20%3C%5C%2Fb%3E%20Profound%20knowledge%20about%20child%20growth%2C%20development%2C%20health%2C%20and%20disease%20in%20contemporary%20children%20and%20adolescents%20is%20still%20rare.%20Epidemiological%20studies%20together%20with%20new%20powerful%20research%20technologies%20present%20exciting%20opportunities%20to%20the%20elucidation%20of%20risk%20factor-outcome%20associations%20with%20potentially%20major%20consequences%20for%20prevention%2C%20diagnosis%20and%20treatment.%5Cn%3Cb%3EAim%3A%20%3C%5C%2Fb%3E%20To%20conduct%20a%20unique%20prospective%20longitudinal%20cohort%20study%20in%20order%20to%20assess%20how%20environmental%2C%20metabolic%20and%20genetic%20factors%20affect%20growth%2C%20development%20and%20health%20from%20fetal%20life%20to%20adulthood.%5Cn%3Cb%3EMethods%3A%20%3C%5C%2Fb%3EThe%20%5Cu2018Leipzig%20Research%20Centre%20for%20Civilization%20Diseases%20%28LIFE%29%20Child%20Study%5Cu2019%20focuses%20on%20two%20main%20research%20objectives%3A%20%281%29%20monitoring%20of%20normal%20growth%2C%20development%20and%20health%3B%20%282%29%20non-communicable%20diseases%20such%20as%20childhood%20obesity%20and%20its%20co-morbidities%2C%20atopy%20and%20mental%20health%20problems.%20Detailed%20assessments%20will%20be%20conducted%20alongside%20long-term%20storage%20of%20biological%20samples%20in%202%2C000%20pregnant%20women%20and%20more%20than%2010%2C000%20children%20and%20their%20families%20%3Cb%3EResults%3A%20%3C%5C%2Fb%3EClose%20coordination%20and%20engagement%20of%20a%20multidisciplinary%20team%20in%20the%20LIFE%20Child%20study%20successfully%20established%20procedures%20and%20systems%20for%20balancing%20many%20competing%20study%20and%20ethical%20needs.%20Full%20participant%20recruitment%20and%20complete%20data%20collection%20started%20in%20July%202011.%20Early%20data%20indicate%20a%20high%20acceptance%20rate%20of%20the%20study%20program%2C%20successful%20recruitment%20strategies%20and%20the%20establishment%20of%20a%20representative%20cohort%20for%20the%20population%20of%20Leipzig.%20A%20series%20of%20subprojects%20are%20ongoing%2C%20and%20analyses%20and%20publications%20are%20on%20their%20way.%5Cn%3Cb%3EDiscussion%3A%20%3C%5C%2Fb%3EThis%20paper%20addresses%20key%20elements%20in%20the%20design%20and%20implementation%20of%20the%20new%20prospective%20longitudinal%20cohort%20study%20LIFE%20Child.%20Given%20the%20recognized%20need%20for%20long-term%20data%20on%20adverse%20effects%20on%20health%20and%20protective%20factors%2C%20our%20study%20data%20collection%20should%20provide%20magnificent%20opportunities%20to%20examine%20complex%20interactions%20that%20govern%20the%20emergence%20of%20non-communicable%20diseases.%22%2C%22date%22%3A%222012-11%22%2C%22language%22%3A%22%22%2C%22DOI%22%3A%2210.1186%5C%2F1471-2458-12-1021%22%2C%22ISSN%22%3A%22%22%2C%22url%22%3A%22http%3A%5C%2F%5C%2Fwww.biomedcentral.com%5C%2F1471-2458%5C%2F12%5C%2F1021%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-27T08%3A48%3A06Z%22%7D%7D%5D%7D
Barzen, Charlotte, Mandy Vogel, Wieland Kiess, and Tanja Poulain. “Associations between Gestational Weight Gain and Weight Development of the Offspring: Differences Depending on Maternal Pre-Pregnancy BMI.” Archives of Gynecology and Obstetrics, April 13, 2024. https://doi.org/10.1007/s00404-024-07487-1.
Dathan-Stumpf, Anne, Mandy Vogel, Nico Grafe, Wieland Kiess, and Holger Stepan. “Relation between Socioeconomic Status and Maternal Serum Lipids to Infant Lipid Concentrations and Anthropometry in the First Year of Life.” Archives of Gynecology and Obstetrics, March 2, 2023. https://doi.org/10.1007/s00404-023-06937-6.
Poulain, Tanja, Ulrike Spielau, Mandy Vogel, Anne Dathan-Stumpf, Antje Körner, and Wieland Kiess. “Changes in Diet from Pregnancy to One Year After Birth: A Longitudinal Study.” BMC Pregnancy and Childbirth 21, no. 1 (September 2021): 600. https://doi.org/10.1186/s12884-021-04038-3.
Eichler, Janina, Ricarda Schmidt, Tanja Poulain, Andreas Hiemisch, Wieland Kiess, and Anja Hilbert. “Maternal Depressive Symptoms and Stress During Pregnancy as Predictors of Gestational Age at Birth and Standardized Body Mass Index from Birth up to 2 Years of Age.” BMC Pregnancy and Childbirth 21, no. 1 (September 2021): 635. https://doi.org/10.1186/s12884-021-04111-x.
Poulain, Tanja, Juliane Ludwig, Mandy Vogel, Andreas Hiemisch, Antje Körner, and Wieland Kiess. “[The LIFE Child study: A cohort study investigating child development in changing environmental conditions].” Zeitschrift Fur Psychosomatische Medizin Und Psychotherapie 66, no. 4 (December 2020): 390–401. https://doi.org/10.13109/zptm.2020.66.4.390.
Schreiter, Juliane, Mandy Vogel, Henriette Kiep, Ulrich Thome, Annett Bläser, Petra Nickel, Wieland Kiess, and Matthias K. Bernhard. “[The Cognitive, Language and Motor Development of Prenatal Methamphetamine- and Opioid-exposed Children].” Klinische Padiatrie 231, no. 5 (September 2019): 262–68. https://doi.org/10.1055/a-0981-6322.
Eichler, Janina, Ricarda Schmidt, Andreas Hiemisch, Wieland Kiess, and Anja Hilbert. “Gestational Weight Gain, Physical Activity, Sleep Problems, Substance Use, and Food Intake as Proximal Risk Factors of Stress and Depressive Symptoms During Pregnancy.” BMC Pregnancy and Childbirth 19, no. 1 (May 2019): 175. https://doi.org/10.1186/s12884-019-2328-1.
Scharlau, Friederike, Diana Pietzner, Mandy Vogel, Alexander Gaudl, Uta Ceglarek, Joachim Thiery, Jürgen Kratzsch, Andreas Hiemisch, and Wieland Kiess. “Evaluation of Hair Cortisol and Cortisone Change During Pregnancy and the Association with Self-Reported Depression, Somatization, and Stress Symptoms.” Stress (Amsterdam, Netherlands) 21, no. 1 (January 2018): 43–50. https://doi.org/10.1080/10253890.2017.1392507.
Pflügner, Alina, Ulrich Thome, Matthias K. Bernhard, Mandy Vogel, Annett Bläser, Petra Nickel, and Wieland Kiess. “[Methamphetamine Consumption During Pregnancy and its Effects on Neonates].” Klinische Padiatrie 230, no. 1 (January 2018): 31–38. https://doi.org/10.1055/s-0043-121991.
Poulain, Tanja, Ronny Baber, Mandy Vogel, Diana Pietzner, Toralf Kirsten, Anne Jurkutat, Andreas Hiemisch, et al. “The Life Child Study: A Population-Based Perinatal and Pediatric Cohort in Germany.” European Journal of Epidemiology 32, no. 2 (January 2017): 145–58. https://doi.org/10.1007/s10654-016-0216-9.
Larsen, Pernille Stemann, Mads Kamper-Jørgensen, Ashley Adamson, Henrique Barros, Jens Peter Bonde, Sonia Brescianini, Sinead Brophy, et al. “Pregnancy and Birth Cohort Resources in Europe: A Large Opportunity for Aetiological Child Health Research.” Paediatric and Perinatal Epidemiology 27, no. 4 (July 2013): 393–414. https://doi.org/10.1111/ppe.12060.
Quante, Mirja, Mara Hesse, Mirko Döhnert, Michael Fuchs, Christian Hirsch, Elena Sergeyev, Nora Casprzig, et al. “The Life Child Study: A Life Course Approach to Disease and Health.” BMC Public Health 12, no. 1 (November 2012): 1021. https://doi.org/10.1186/1471-2458-12-1021.
2390247
T52N9QLZ
mops
1
chicago-fullnote-bibliography
50
date
desc
1
1
6748
https://home.uni-leipzig.de/lifechild/wp-content/plugins/zotpress/
2390247
T52N9QLZ
LCgen
1
chicago-fullnote-bibliography
50
date
desc
1
1
6748
https://home.uni-leipzig.de/lifechild/wp-content/plugins/zotpress/
%7B%22status%22%3A%22success%22%2C%22updateneeded%22%3Afalse%2C%22instance%22%3Afalse%2C%22meta%22%3A%7B%22request_last%22%3A0%2C%22request_next%22%3A0%2C%22used_cache%22%3Atrue%7D%2C%22data%22%3A%5B%7B%22key%22%3A%22I6AVCS6H%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Tomar%20et%20al.%22%2C%22parsedDate%22%3A%222024-06-05%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3ETomar%2C%20A.%2C%20M.%20Gomez-Velazquez%2C%20R.%20Gerlini%2C%20G.%20Comas-Armangu%26%23xE9%3B%2C%20L.%20Makharadze%2C%20T.%20Kolbe%2C%20A.%20Boersma%2C%20et%20al.%20%26%23x201C%3BEpigenetic%20Inheritance%20of%20Diet-Induced%20and%20Sperm-Borne%20Mitochondrial%20RNAs.%26%23x201D%3B%20%3Ci%3ENature%3C%5C%2Fi%3E%2C%20June%205%2C%202024%2C%201%26%23×2013%3B8.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1038%5C%2Fs41586-024-07472-3%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1038%5C%2Fs41586-024-07472-3%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Epigenetic%20inheritance%20of%20diet-induced%20and%20sperm-borne%20mitochondrial%20RNAs%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22A.%22%2C%22lastName%22%3A%22Tomar%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22M.%22%2C%22lastName%22%3A%22Gomez-Velazquez%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22R.%22%2C%22lastName%22%3A%22Gerlini%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22G.%22%2C%22lastName%22%3A%22Comas-Armangu%5Cu00e9%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22L.%22%2C%22lastName%22%3A%22Makharadze%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22T.%22%2C%22lastName%22%3A%22Kolbe%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22A.%22%2C%22lastName%22%3A%22Boersma%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22M.%22%2C%22lastName%22%3A%22Dahlhoff%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J.%20P.%22%2C%22lastName%22%3A%22Burgstaller%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22M.%22%2C%22lastName%22%3A%22Lassi%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J.%22%2C%22lastName%22%3A%22Darr%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J.%22%2C%22lastName%22%3A%22Toppari%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22H.%22%2C%22lastName%22%3A%22Virtanen%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22A.%22%2C%22lastName%22%3A%22K%5Cu00fchnapfel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22M.%22%2C%22lastName%22%3A%22Scholz%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22K.%22%2C%22lastName%22%3A%22Landgraf%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22W.%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22M.%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22V.%22%2C%22lastName%22%3A%22Gailus-Durner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22H.%22%2C%22lastName%22%3A%22Fuchs%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22S.%22%2C%22lastName%22%3A%22Marschall%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22M.%22%2C%22lastName%22%3A%22Hrab%5Cu011b%20de%20Angelis%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22N.%22%2C%22lastName%22%3A%22Kotaja%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22A.%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22R.%22%2C%22lastName%22%3A%22Teperino%22%7D%5D%2C%22abstractNote%22%3A%22Spermatozoa%20harbour%20a%20complex%20and%20environment-sensitive%20pool%20of%20small%20non-coding%20RNAs%20%28sncRNAs%291%2C%20which%20influences%20offspring%20development%20and%20adult%20phenotypes1%5Cu20137.%20Whether%20spermatozoa%20in%20the%20epididymis%20are%20directly%20susceptible%20to%20environmental%20cues%20is%20not%20fully%20understood8.%20Here%20we%20used%20two%20distinct%20paradigms%20of%20preconception%20acute%20high-fat%20diet%20to%20dissect%20epididymal%20versus%20testicular%20contributions%20to%20the%20sperm%20sncRNA%20pool%20and%20offspring%20health.%20We%20show%20that%20epididymal%20spermatozoa%2C%20but%20not%20developing%20germ%20cells%2C%20are%20sensitive%20to%20the%20environment%20and%20identify%20mitochondrial%20tRNAs%20%28mt-tRNAs%29%20and%20their%20fragments%20%28mt-tsRNAs%29%20as%20sperm-borne%20factors.%20In%20humans%2C%20mt-tsRNAs%20in%20spermatozoa%20correlate%20with%20body%20mass%20index%2C%20and%20paternal%20overweight%20at%20conception%20doubles%20offspring%20obesity%20risk%20and%20compromises%20metabolic%20health.%20Sperm%20sncRNA%20sequencing%20of%20mice%20mutant%20for%20genes%20involved%20in%20mitochondrial%20function%2C%20and%20metabolic%20phenotyping%20of%20their%20wild-type%20offspring%2C%20suggest%20that%20the%20upregulation%20of%20mt-tsRNAs%20is%20downstream%20of%20mitochondrial%20dysfunction.%20Single-embryo%20transcriptomics%20of%20genetically%20hybrid%20two-cell%20embryos%20demonstrated%20sperm-to-oocyte%20transfer%20of%20mt-tRNAs%20at%20fertilization%20and%20suggested%20their%20involvement%20in%20the%20control%20of%20early-embryo%20transcription.%20Our%20study%20supports%20the%20importance%20of%20paternal%20health%20at%20conception%20for%20offspring%20metabolism%2C%20shows%20that%20mt-tRNAs%20are%20diet-induced%20and%20sperm-borne%20and%20demonstrates%2C%20in%20a%20physiological%20setting%2C%20father-to-offspring%20transfer%20of%20sperm%20mitochondrial%20RNAs%20at%20fertilization.%22%2C%22date%22%3A%222024-06-05%22%2C%22language%22%3A%22en%22%2C%22DOI%22%3A%2210.1038%5C%2Fs41586-024-07472-3%22%2C%22ISSN%22%3A%221476-4687%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fwww.nature.com%5C%2Farticles%5C%2Fs41586-024-07472-3%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222024-08-27T12%3A32%3A38Z%22%7D%7D%2C%7B%22key%22%3A%22HT7DRXIX%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Vogelezang%20et%20al.%22%2C%22parsedDate%22%3A%222022-06-04%22%2C%22numChildren%22%3A2%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EVogelezang%2C%20Suzanne%2C%20Jonathan%20P.%20Bradfield%2C%20Early%20Growth%20Genetics%20Consortium%2C%20Struan%20F.%20A.%20Grant%2C%20Janine%20F.%20Felix%2C%20and%20Vincent%20W.%20V.%20Jaddoe.%20%26%23x201C%3BGenetics%20of%20Early-Life%20Head%20Circumference%20and%20Genetic%20Correlations%20with%20Neurological%2C%20Psychiatric%20and%20Cognitive%20Outcomes.%26%23x201D%3B%20%3Ci%3EBMC%20Medical%20Genomics%3C%5C%2Fi%3E%2015%2C%20no.%201%20%28June%204%2C%202022%29%3A%20124.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs12920-022-01281-1%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2Fs12920-022-01281-1%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Genetics%20of%20early-life%20head%20circumference%20and%20genetic%20correlations%20with%20neurological%2C%20psychiatric%20and%20cognitive%20outcomes%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Suzanne%22%2C%22lastName%22%3A%22Vogelezang%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Jonathan%20P.%22%2C%22lastName%22%3A%22Bradfield%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22name%22%3A%22Early%20Growth%20Genetics%20Consortium%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Struan%20F.%20A.%22%2C%22lastName%22%3A%22Grant%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Janine%20F.%22%2C%22lastName%22%3A%22Felix%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Vincent%20W.%20V.%22%2C%22lastName%22%3A%22Jaddoe%22%7D%5D%2C%22abstractNote%22%3A%22BACKGROUND%3A%20Head%20circumference%20is%20associated%20with%20intelligence%20and%20tracks%20from%20childhood%20into%20adulthood.%5CnMETHODS%3A%20We%20performed%20a%20genome-wide%20association%20study%20meta-analysis%20and%20follow-up%20of%20head%20circumference%20in%20a%20total%20of%2029%2C192%20participants%20between%206%20and%2030%5Cu00a0months%20of%20age.%5CnRESULTS%3A%20Seven%20loci%20reached%20genome-wide%20significance%20in%20the%20combined%20discovery%20and%20replication%20analysis%20of%20which%20three%20loci%20near%20ARFGEF2%2C%20MYCL1%2C%20and%20TOP1%2C%20were%20novel.%20We%20observed%20positive%20genetic%20correlations%20for%20early-life%20head%20circumference%20with%20adult%20intracranial%20volume%2C%20years%20of%20schooling%2C%20childhood%20and%20adult%20intelligence%2C%20but%20not%20with%20adult%20psychiatric%2C%20neurological%2C%20or%20personality-related%20phenotypes.%5CnCONCLUSIONS%3A%20The%20results%20of%20this%20study%20indicate%20that%20the%20biological%20processes%20underlying%20early-life%20head%20circumference%20overlap%20largely%20with%20those%20of%20adult%20head%20circumference.%20The%20associations%20of%20early-life%20head%20circumference%20with%20cognitive%20outcomes%20across%20the%20life%20course%20are%20partly%20explained%20by%20genetics.%22%2C%22date%22%3A%222022-06-04%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1186%5C%2Fs12920-022-01281-1%22%2C%22ISSN%22%3A%221755-8794%22%2C%22url%22%3A%22%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222024-08-27T13%3A14%3A55Z%22%7D%7D%2C%7B%22key%22%3A%22KCY7IZX4%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Poulain%20et%20al.%22%2C%22parsedDate%22%3A%222017-01%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EPoulain%2C%20Tanja%2C%20Ronny%20Baber%2C%20Mandy%20Vogel%2C%20Diana%20Pietzner%2C%20Toralf%20Kirsten%2C%20Anne%20Jurkutat%2C%20Andreas%20Hiemisch%2C%20et%20al.%20%26%23x201C%3BThe%20Life%20Child%20Study%3A%20A%20Population-Based%20Perinatal%20and%20Pediatric%20Cohort%20in%20Germany.%26%23x201D%3B%20%3Ci%3EEuropean%20Journal%20of%20Epidemiology%3C%5C%2Fi%3E%2032%2C%20no.%202%20%28January%202017%29%3A%20145%26%23×2013%3B58.%20%3Ca%20class%3D%27zp-ItemURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs10654-016-0216-9%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs10654-016-0216-9%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22The%20Life%20Child%20Study%3A%20A%20Population-Based%20Perinatal%20and%20Pediatric%20Cohort%20in%20Germany%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tanja%22%2C%22lastName%22%3A%22Poulain%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Ronny%22%2C%22lastName%22%3A%22Baber%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Vogel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Diana%22%2C%22lastName%22%3A%22Pietzner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Toralf%22%2C%22lastName%22%3A%22Kirsten%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anne%22%2C%22lastName%22%3A%22Jurkutat%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andreas%22%2C%22lastName%22%3A%22Hiemisch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Anja%22%2C%22lastName%22%3A%22Hilbert%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22J%5Cu00fcrgen%22%2C%22lastName%22%3A%22Kratzsch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Joachim%22%2C%22lastName%22%3A%22Thiery%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Michael%22%2C%22lastName%22%3A%22Fuchs%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christian%22%2C%22lastName%22%3A%22Hirsch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Franziska%20G.%22%2C%22lastName%22%3A%22Rauscher%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Markus%22%2C%22lastName%22%3A%22Loeffler%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Matthias%22%2C%22lastName%22%3A%22N%5Cu00fcchter%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22name%22%3A%22LIFE%20Child%20study%20team%22%7D%5D%2C%22abstractNote%22%3A%22The%20LIFE%20Child%20study%20is%20a%20large%20population-based%20longitudinal%20childhood%20cohort%20study%20conducted%20in%20the%20city%20of%20Leipzig%2C%20Germany.%20As%20a%20part%20of%20LIFE%2C%20a%20research%20project%20conducted%20at%20the%20Leipzig%20Research%20Center%20for%20Civilization%20Diseases%2C%20it%20aims%20to%20monitor%20healthy%20child%20development%20from%20birth%20to%20adulthood%20and%20to%20understand%20the%20development%20of%20lifestyle%20diseases%20such%20as%20obesity.%20The%20study%20consists%20of%20three%20interrelated%20cohorts%3B%20the%20birth%20cohort%2C%20the%20health%20cohort%2C%20and%20the%20obesity%20cohort.%20Depending%20on%20age%20and%20cohort%2C%20the%20comprehensive%20study%20program%20comprises%20different%20medical%2C%20psychological%2C%20and%20sociodemographic%20assessments%20as%20well%20as%20the%20collection%20of%20biological%20samples.%20Optimal%20data%20acquisition%2C%20process%20management%2C%20and%20data%20analysis%20are%20guaranteed%20by%20a%20professional%20team%20of%20physicians%2C%20certified%20study%20assistants%2C%20quality%20managers%2C%20scientists%20and%20statisticians.%20Due%20to%20the%20high%20popularity%20of%20the%20study%2C%20more%20than%203000%20children%20have%20already%20participated%20until%20the%20end%20of%202015%2C%20and%20two-thirds%20of%20them%20participate%20continuously.%20The%20large%20quantity%20of%20acquired%20data%20allows%20LIFE%20Child%20to%20gain%20profound%20knowledge%20on%20the%20development%20of%20children%20growing%20up%20in%20the%20twenty-first%20century.%20This%20article%20reports%20the%20number%20of%20available%20and%20analyzable%20data%20and%20demonstrates%20the%20high%20relevance%20and%20potential%20of%20the%20study.%22%2C%22date%22%3A%22January%2C%202017%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1007%5C%2Fs10654-016-0216-9%22%2C%22ISSN%22%3A%221573-7284%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs10654-016-0216-9%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-12-28T13%3A15%3A46Z%22%7D%7D%2C%7B%22key%22%3A%22KP78ICZT%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Quante%20et%20al.%22%2C%22parsedDate%22%3A%222015-01%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EQuante%2C%20Mirja%2C%20Sarah%20Bruckmann%2C%20Tillman%20Wallborn%2C%20Nadine%20Wolf%2C%20Elena%20Sergeyev%2C%20Melanie%20Adler%2C%20Mara%20Hesse%2C%20et%20al.%20%26%23x201C%3BManaging%20Incidental%20Findings%20and%20Disclosure%20of%20Results%20in%20a%20Paediatric%20Research%20Cohort%20-%20the%20Life%20Child%20Study%20Cohort.%26%23x201D%3B%20%3Ci%3EJournal%20of%20Pediatric%20Endocrinology%20%26amp%3B%20Metabolism%3A%20JPEM%3C%5C%2Fi%3E%2028%2C%20no.%201%26%23×2013%3B2%20%28January%202015%29%3A%2075%26%23×2013%3B82.%20%3Ca%20class%3D%27zp-ItemURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1515%5C%2Fjpem-2014-0079%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1515%5C%2Fjpem-2014-0079%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Managing%20Incidental%20Findings%20and%20Disclosure%20of%20Results%20in%20a%20Paediatric%20Research%20Cohort%20-%20the%20Life%20Child%20Study%20Cohort%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mirja%22%2C%22lastName%22%3A%22Quante%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Sarah%22%2C%22lastName%22%3A%22Bruckmann%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tillman%22%2C%22lastName%22%3A%22Wallborn%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Nadine%22%2C%22lastName%22%3A%22Wolf%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Elena%22%2C%22lastName%22%3A%22Sergeyev%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Melanie%22%2C%22lastName%22%3A%22Adler%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mara%22%2C%22lastName%22%3A%22Hesse%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Geserick%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Stephanie%22%2C%22lastName%22%3A%22Naumann%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christiane%22%2C%22lastName%22%3A%22Koch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Harini%22%2C%22lastName%22%3A%22Nivarthi%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christoph%22%2C%22lastName%22%3A%22Engel%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Antje%22%2C%22lastName%22%3A%22K%5Cu00f6rner%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andreas%22%2C%22lastName%22%3A%22Hiemisch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22name%22%3A%22LIFE%20Child%20Study%20Investigators%22%7D%5D%2C%22abstractNote%22%3A%22%3Cb%3EOBJECTIVE%3A%3C%5C%2Fb%3E%20To%20assess%20the%20frequency%20of%20incidental%20findings%20%28IFs%29%20in%20the%20population-based%20%5C%22Leipzig%20Research%20Centre%20for%20Civilization%20Diseases%20%28LIFE%29%20Child%20Study%5C%22%20within%201%20year.%5CnMETHODS%3A%20From%20July%202011%20to%20June%202012%2C%20969%20children%20participated%20in%20the%20study.%20The%20IFs%20were%20analysed%20with%20respect%20to%20age%2C%20gender%2C%20type%20of%20examination%20and%20clinical%20action%20taken.%5Cn%3Cb%3ERESULTS%3A%3C%5C%2Fb%3E%20The%20IFs%20were%20detected%20in%2063%20participants%20%286.5%25%29%2C%20including%20five%20children%20who%20presented%20with%20two%20IFs%20simultaneously.%20Eleven%20children%20received%20a%20new%2C%20hence%20previously%20unknown%2C%20clinical%20diagnosis.%20Alternatively%2C%2018%20IFs%20could%20not%20be%20confirmed%20or%20were%20of%20a%20transient%20and%20self-limiting%20condition.%20The%20frequency%20of%20IFs%20varied%20widely%20depending%20on%20the%20type%20of%20examination%2C%20but%20did%20not%20differ%20by%20gender.%5Cn%3Cb%3ECONCLUSION%3A%3C%5C%2Fb%3E%20Although%20IFs%20were%20common%20events%2C%20there%20was%20no%20finding%20with%20a%20profound%20clinical%20impact%20on%20the%20subject%27s%20life.%20Our%20current%20IF%20management%20protocol%20may%20be%20useful%20in%20creating%20management%20plans%20for%20other%20cohort%20studies.%22%2C%22date%22%3A%22January%202015%22%2C%22language%22%3A%22eng%22%2C%22DOI%22%3A%2210.1515%5C%2Fjpem-2014-0079%22%2C%22ISSN%22%3A%222191-0251%22%2C%22url%22%3A%22https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1515%5C%2Fjpem-2014-0079%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-27T08%3A47%3A38Z%22%7D%7D%2C%7B%22key%22%3A%229SCAWI3Y%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Wallborn%20et%20al.%22%2C%22parsedDate%22%3A%222013-03%22%2C%22numChildren%22%3A1%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EWallborn%2C%20Tillmann%2C%20Nico%20Grafe%2C%20Mirja%20Quante%2C%20Mandy%20Geserick%2C%20Nora%20Casprzig%2C%20Juliane%20Ludwig%2C%20Andreas%20Hiemisch%2C%20and%20Wieland%20Kiess.%20%26%23x201C%3BNever%20Plan%20a%20Population%20Based%20Cohort%20Study%20on%20a%20Rainy%20Friday%20After%20a%20Sunny%20Thursday.%26%23x201D%3B%20%3Ci%3EEuropean%20Journal%20of%20Epidemiology%3C%5C%2Fi%3E%2028%20%28March%202013%29%3A%20285%26%23×2013%3B86.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs10654-013-9774-2%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1007%5C%2Fs10654-013-9774-2%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22Never%20Plan%20a%20Population%20Based%20Cohort%20Study%20on%20a%20Rainy%20Friday%20After%20a%20Sunny%20Thursday%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Tillmann%22%2C%22lastName%22%3A%22Wallborn%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Nico%22%2C%22lastName%22%3A%22Grafe%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mirja%22%2C%22lastName%22%3A%22Quante%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Geserick%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Nora%22%2C%22lastName%22%3A%22Casprzig%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Juliane%22%2C%22lastName%22%3A%22Ludwig%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Andreas%22%2C%22lastName%22%3A%22Hiemisch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Wieland%22%2C%22lastName%22%3A%22Kiess%22%7D%5D%2C%22abstractNote%22%3A%22Many%20cohort%20studies%20have%20identified%20factors%20such%20as%20low%20SES%20leading%20to%20higher%20attrition%20or%20drop-out%20rates%20of%20study%20subkects%20%281%2C2%29.%20But%20no%20study%20has%20addressed%20until%20now%20the%20influence%20of%20weather%20conditions%20or%20general%20cultural%20factors%20on%20the%20rate%20of%20missed%20or%20canceled%20study%20appointments.%20We%20analyzed%20the%20first-contact%20drop-out%20rate%20over%20a%20period%20of%201%20year%20and%207%20months%20in%20the%20German%20LIFE-Child%20cohort%20study%20and%20found%20out%20a%20higher%20risk%20of%20cancellation%20or%20missed%20appointments%20on%20Fridays%20compared%20to%20Mondays%2C%20on%20rainy%20days%2C%20on%20days%20hotter%20than%20usual%20and%20on%20days%20following%20days%20of%20longer%20sunshine.%20We%20conclude%20that%20it%20would%20be%20advisable%20to%20adjust%20the%20scheduling%20strategies%20to%20these%20results.%22%2C%22date%22%3A%222013-03%22%2C%22language%22%3A%22%22%2C%22DOI%22%3A%2210.1007%5C%2Fs10654-013-9774-2%22%2C%22ISSN%22%3A%22%22%2C%22url%22%3A%22http%3A%5C%2F%5C%2Fsearch.proquest.com%5C%2Fopenview%5C%2Febfb70c057f8273268e9dfdcd5b78c8c%5C%2F1%3Fpq-origsite%3Dgscholar%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-27T09%3A01%3A16Z%22%7D%7D%2C%7B%22key%22%3A%225VYVU76M%22%2C%22library%22%3A%7B%22id%22%3A2390247%7D%2C%22meta%22%3A%7B%22creatorSummary%22%3A%22Quante%20et%20al.%22%2C%22parsedDate%22%3A%222012-11%22%2C%22numChildren%22%3A2%7D%2C%22bib%22%3A%22%3Cdiv%20class%3D%5C%22csl-bib-body%5C%22%20style%3D%5C%22line-height%3A%201.35%3B%20padding-left%3A%201em%3B%20text-indent%3A-1em%3B%5C%22%3E%5Cn%20%20%3Cdiv%20class%3D%5C%22csl-entry%5C%22%3EQuante%2C%20Mirja%2C%20Mara%20Hesse%2C%20Mirko%20D%26%23xF6%3Bhnert%2C%20Michael%20Fuchs%2C%20Christian%20Hirsch%2C%20Elena%20Sergeyev%2C%20Nora%20Casprzig%2C%20et%20al.%20%26%23x201C%3BThe%20Life%20Child%20Study%3A%20A%20Life%20Course%20Approach%20to%20Disease%20and%20Health.%26%23x201D%3B%20%3Ci%3EBMC%20Public%20Health%3C%5C%2Fi%3E%2012%2C%20no.%201%20%28November%202012%29%3A%201021.%20%3Ca%20class%3D%27zp-DOIURL%27%20target%3D%27_blank%27%20href%3D%27https%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2F1471-2458-12-1021%27%3Ehttps%3A%5C%2F%5C%2Fdoi.org%5C%2F10.1186%5C%2F1471-2458-12-1021%3C%5C%2Fa%3E.%3C%5C%2Fdiv%3E%5Cn%3C%5C%2Fdiv%3E%22%2C%22data%22%3A%7B%22itemType%22%3A%22journalArticle%22%2C%22title%22%3A%22The%20Life%20Child%20Study%3A%20A%20Life%20Course%20Approach%20to%20Disease%20and%20Health%22%2C%22creators%22%3A%5B%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mirja%22%2C%22lastName%22%3A%22Quante%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mara%22%2C%22lastName%22%3A%22Hesse%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mirko%22%2C%22lastName%22%3A%22D%5Cu00f6hnert%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Michael%22%2C%22lastName%22%3A%22Fuchs%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christian%22%2C%22lastName%22%3A%22Hirsch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Elena%22%2C%22lastName%22%3A%22Sergeyev%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Nora%22%2C%22lastName%22%3A%22Casprzig%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Mandy%22%2C%22lastName%22%3A%22Geserick%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Stephanie%22%2C%22lastName%22%3A%22Naumann%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22firstName%22%3A%22Christiane%22%2C%22lastName%22%3A%22Koch%22%7D%2C%7B%22creatorType%22%3A%22author%22%2C%22name%22%3A%22others%22%7D%5D%2C%22abstractNote%22%3A%22%3Cb%3EBackground%3A%20%3C%5C%2Fb%3E%20Profound%20knowledge%20about%20child%20growth%2C%20development%2C%20health%2C%20and%20disease%20in%20contemporary%20children%20and%20adolescents%20is%20still%20rare.%20Epidemiological%20studies%20together%20with%20new%20powerful%20research%20technologies%20present%20exciting%20opportunities%20to%20the%20elucidation%20of%20risk%20factor-outcome%20associations%20with%20potentially%20major%20consequences%20for%20prevention%2C%20diagnosis%20and%20treatment.%5Cn%3Cb%3EAim%3A%20%3C%5C%2Fb%3E%20To%20conduct%20a%20unique%20prospective%20longitudinal%20cohort%20study%20in%20order%20to%20assess%20how%20environmental%2C%20metabolic%20and%20genetic%20factors%20affect%20growth%2C%20development%20and%20health%20from%20fetal%20life%20to%20adulthood.%5Cn%3Cb%3EMethods%3A%20%3C%5C%2Fb%3EThe%20%5Cu2018Leipzig%20Research%20Centre%20for%20Civilization%20Diseases%20%28LIFE%29%20Child%20Study%5Cu2019%20focuses%20on%20two%20main%20research%20objectives%3A%20%281%29%20monitoring%20of%20normal%20growth%2C%20development%20and%20health%3B%20%282%29%20non-communicable%20diseases%20such%20as%20childhood%20obesity%20and%20its%20co-morbidities%2C%20atopy%20and%20mental%20health%20problems.%20Detailed%20assessments%20will%20be%20conducted%20alongside%20long-term%20storage%20of%20biological%20samples%20in%202%2C000%20pregnant%20women%20and%20more%20than%2010%2C000%20children%20and%20their%20families%20%3Cb%3EResults%3A%20%3C%5C%2Fb%3EClose%20coordination%20and%20engagement%20of%20a%20multidisciplinary%20team%20in%20the%20LIFE%20Child%20study%20successfully%20established%20procedures%20and%20systems%20for%20balancing%20many%20competing%20study%20and%20ethical%20needs.%20Full%20participant%20recruitment%20and%20complete%20data%20collection%20started%20in%20July%202011.%20Early%20data%20indicate%20a%20high%20acceptance%20rate%20of%20the%20study%20program%2C%20successful%20recruitment%20strategies%20and%20the%20establishment%20of%20a%20representative%20cohort%20for%20the%20population%20of%20Leipzig.%20A%20series%20of%20subprojects%20are%20ongoing%2C%20and%20analyses%20and%20publications%20are%20on%20their%20way.%5Cn%3Cb%3EDiscussion%3A%20%3C%5C%2Fb%3EThis%20paper%20addresses%20key%20elements%20in%20the%20design%20and%20implementation%20of%20the%20new%20prospective%20longitudinal%20cohort%20study%20LIFE%20Child.%20Given%20the%20recognized%20need%20for%20long-term%20data%20on%20adverse%20effects%20on%20health%20and%20protective%20factors%2C%20our%20study%20data%20collection%20should%20provide%20magnificent%20opportunities%20to%20examine%20complex%20interactions%20that%20govern%20the%20emergence%20of%20non-communicable%20diseases.%22%2C%22date%22%3A%222012-11%22%2C%22language%22%3A%22%22%2C%22DOI%22%3A%2210.1186%5C%2F1471-2458-12-1021%22%2C%22ISSN%22%3A%22%22%2C%22url%22%3A%22http%3A%5C%2F%5C%2Fwww.biomedcentral.com%5C%2F1471-2458%5C%2F12%5C%2F1021%22%2C%22collections%22%3A%5B%22T52N9QLZ%22%5D%2C%22dateModified%22%3A%222023-11-27T08%3A48%3A06Z%22%7D%7D%5D%7D
Tomar, A., M. Gomez-Velazquez, R. Gerlini, G. Comas-Armangué, L. Makharadze, T. Kolbe, A. Boersma, et al. “Epigenetic Inheritance of Diet-Induced and Sperm-Borne Mitochondrial RNAs.” Nature, June 5, 2024, 1–8. https://doi.org/10.1038/s41586-024-07472-3.
Vogelezang, Suzanne, Jonathan P. Bradfield, Early Growth Genetics Consortium, Struan F. A. Grant, Janine F. Felix, and Vincent W. V. Jaddoe. “Genetics of Early-Life Head Circumference and Genetic Correlations with Neurological, Psychiatric and Cognitive Outcomes.” BMC Medical Genomics 15, no. 1 (June 4, 2022): 124. https://doi.org/10.1186/s12920-022-01281-1.
Poulain, Tanja, Ronny Baber, Mandy Vogel, Diana Pietzner, Toralf Kirsten, Anne Jurkutat, Andreas Hiemisch, et al. “The Life Child Study: A Population-Based Perinatal and Pediatric Cohort in Germany.” European Journal of Epidemiology 32, no. 2 (January 2017): 145–58. https://doi.org/10.1007/s10654-016-0216-9.
Quante, Mirja, Sarah Bruckmann, Tillman Wallborn, Nadine Wolf, Elena Sergeyev, Melanie Adler, Mara Hesse, et al. “Managing Incidental Findings and Disclosure of Results in a Paediatric Research Cohort – the Life Child Study Cohort.” Journal of Pediatric Endocrinology & Metabolism: JPEM 28, no. 1–2 (January 2015): 75–82. https://doi.org/10.1515/jpem-2014-0079.
Wallborn, Tillmann, Nico Grafe, Mirja Quante, Mandy Geserick, Nora Casprzig, Juliane Ludwig, Andreas Hiemisch, and Wieland Kiess. “Never Plan a Population Based Cohort Study on a Rainy Friday After a Sunny Thursday.” European Journal of Epidemiology 28 (March 2013): 285–86. https://doi.org/10.1007/s10654-013-9774-2.
Quante, Mirja, Mara Hesse, Mirko Döhnert, Michael Fuchs, Christian Hirsch, Elena Sergeyev, Nora Casprzig, et al. “The Life Child Study: A Life Course Approach to Disease and Health.” BMC Public Health 12, no. 1 (November 2012): 1021. https://doi.org/10.1186/1471-2458-12-1021.