| US
Patent No. 7,435,568 "Optical Cell Guidance Method and Apparatus" |
| Abstract: Embodiments
of the invention include Optical Cell Guidance (OCG) methods and apparatus
to control cell growth. This system guides the leading edge of motile cells
with an optical gradient, which biases the cell's motion into the light
by pulling on proteins, which act like soft dielectrics in the electromagnetic
field. OCG differs from those devices described above in that it controls
the direction of cell motility. This is an entirely new field, and the
first device to directly manipulate cell motility. OCG differs from current
approaches in that it does not trap or hold particles. Instead of trapping
and pulling the cell, the goal of OCG is to influence, direct, and control
the growth of a growth cone.
|
| Inventors: Josef Käs, Mark Raizen, Valery Milner,
Timo Betz, and Allen Ehrlicher |
| (Nov 2002) |
| European
Patent No. EP1455670 "Optical Cell Guidance Method and Apparatus" |
| Abstract: Embodiments
of the invention include Optical Cell Guidance (OCG) methods and apparatus
to control cell growth. This system guides the leading edge of motile cells
with an optical gradient, which biases the cell's motion into the light
by pulling on proteins, which act like soft dielectrics in the electromagnetic
field. OCG differs from those devices described above in that it controls
the direction of cell motility. This is an entirely new field, and the
first device to directly manipulate cell motility. OCG differs from current
approaches in that it does not trap or hold particles. Instead of trapping
and pulling the cell, the goal of OCG is to influence, direct, and control
the growth of a growth cone.
|
| Inventors: Josef Käs, Mark Raizen, Valery Milner,
Timo Betz, and Allen Ehrlicher |
| (Nov 2002) |
| US
Patent No. 6,067,859 "Optical Stretcher" |
| Abstract: This invention
concerns a novel optical micromanipulation tool, referred to as the optical
stretcher, which may use a tunable laser to trap and deform cells between
two counterpropogating beams generated by the laser. It is possible to
detect the deformation of cancer cells.
|
| Inventors: Josef A. Käs and Jochen R. Guck |
| (May 2000) |
| European
Patent No. EP1059871 "Optical Stretcher" |
| Abstract: This invention
concerns a novel optical micromanipulation tool, referred to as the optical
stretcher, which may use a tunable laser to trap and deform cells between
two counterpropogating beams generated by the laser. It is possible to
detect the deformation of cancer cells.
|
| Inventors: Josef Käs and Jochen Guck |
| (Nov. 2000) |
Patents
