Aghamolaei, M., Jafari, Z., Grimm, S., Zarnowiec, K., Najafi-Koopaie, M., & Escera, C. (2018). The effects of aging on early stages of the auditory deviance detection system. Clinical Neurophysiology, 129(11), 2252-2258.

The effects of aging on early stages of the auditory deviance detection system

Objective: The aging effects on auditory change detection have been studied using the MismatchNegativity (MMN) potential. However, recent studies have found earlier correlates of deviance detectionat the level of the middle-latency response (MLR) and the effects of aging on this deviant-relatedresponse have not yet been clarified. The purpose of this study was to examine the effects of aging onboth levels of the auditory deviance detection system.Methods: MMN and MLR responses were recorded in 33 young and 29 older adults from 32 scalp elec-trodes during frequency oddball and swapped-oddball conditions.Results: In the young group, modulation of MLR and a clear MMN response were observed, whereas in theaged group, no evidence of deviance detection was found at the level of MLR and the MMN amplitude wassignificantly diminished.Conclusions: Based on the obtained results, aging affects both levels of the auditory deviance detectionsystem which seems to be a result of deficits in regularity encoding along the auditory hierarchy.Significance: The current findings suggest that age-related physiological changes result in deficits in reg-ularity encoding, starting from early stages of processing. This might eventually affect stream segregationand induce difficulties in understanding speech in complex environments.


Cognitive and Biological Psychology

University of Leipzig
Faculty of Life Sciences
Institute of Psychology
Neumarkt 9-19
D-04109 Leipzig


Dagmar Schrödl
Phone: +49 341 97-39570
Email: dagmar dot schroedl at uni-leipzig dot de

Fax: +49 341 97-39271