2021
J Ye, J Teske, U Kemper, R Seidel.
Sequential Pull‐Down Purification of DNA Origami Superstructures.
Small 2007218 (2021) pdf
2020
I Ceppi, S M Howard, K Kasaciunaite, C Pinto, R Anand, R Seidel, P Cejka.
CtIP promotes the motor activity of DNA2 to accelerate long-range DNA end resection.
Proc. Natl. Acad. Sci. U.S.A. 117 (16), 8859-8869 (2020) pdf
P Irmisch, T. E. Ouldridge, R Seidel.
Modelling DNA-strand displacement reactions in the presence of base-pair mismatches.
J. Am. Chem. Soc. 142, 11451-11463 (2020) pdf
R Grigaitis, L Ranjha, P Wild, K Kasaciunaite, I Ceppi, V Kissling, A Henggeler, A Susperregui, M Peter, R Seidel, P Cejka, J Matos.
Phosphorylation of the RecQ Helicase Sgs1/BLM Controls Its DNA Unwinding Activity during Meiosis and Mitosis.
Developmental Cell 53, 1-18 (2020) pdf
J Ye, R Weichelt, U Kemper, V Gupta, T König, A Eychmüller, R Seidel.
Casting of Gold Nanoparticles with High Aspect Ratios inside DNA Molds.
Small 2003662 (2020) pdf
2019
F Scheffler, M Brueckner, J Ye, R Seidel, U Reibetanz.
A Hybrid Carrier System Based on Origami Nanostructures and Layer-by-Layer Microparticles.
Adv. Funct. Mat. 29, 1808116 (2019) pdf
J Dikic, R Seidel.
Anticooperative Binding Governs the Mechanics of Ethidium-Complexed DNA.
Biophys. J. 116, 1394-1405 (2019) pdf
R Weichelt, J Ye, U Banin, A Eychmüller, R Seidel.
DNA-mediated Self-assembly and Metallization of Semiconductor Nanorods for the Fabrication of Nanoelectronic Interfaces.
Chemistry 25, 9012-9016 (2019) pdf
J Ye, S Helmi, J Teske, R Seidel.
Fabrication of Metal Nanostructures with Programmable Length and Patterns Using a Modular DNA Platform.
Nano Lett. 19, 2707-2714 (2019) pdf
K Kasaciunaite, F Fettes, M Levikova, P Daldrop, R Anand, P Cejka, R Seidel.
Competing interaction partners modulate the activity of Sgs1 helicase during DNA end resection.
EMBO J. 38, e101516 (2019) pdf
I Songailiene, M Rutkauskas, T Sinkunas, E Manakova, S Wittig, C Schmidt, V Siksnys, R Seidel.
Decision-Making in Cascade Complexes Harboring crRNAs of Altered Length.
Cell Reports 28, 3157-3166 (2019) pdf
R Bosire, P Nánási Jr., L Imre, B Dienes, Á Szöőr, A Mázló, A Kovács, R Seidel, G Vámosi, G Szab.
Intercalation of small molecules into DNA in chromatin is primarily controlled by superhelical constraint.
PLoS ONE 14, e0224936 (2019) pdf
2018
A Krivoy, M Rutkauskas, K Kuznedelov, O Musharove, C Rouillon, K Severinov, R Seidel.
Primed CRISPR Adaptation in Escherichia Coli Cells Does Not Depend on Conformational Changes in the Cascade Effector Complex Detected in Vitro.
Nucleic Acids Res. 46 (8), 4087-4098(2018) pdf
T Bayrak, S Helmi, J Ye, DJ Kauert, J Kelling, T Schönherr, R Weichelt, A Erbe, R Seidel.
DNA mold templated assembly of conductive gold nanowires.
Nano Lett. 18 (3), 2116-2123 (2018) pdf
2017
G Kostiuk, J Dikic, FW Schwarz, G Sasnauskas, R Seidel, V Siksnys.
The dynamics of the monomeric restriction endonuclease BcnI during its interaction with DNA.
Nucleic Acids Res. 45(10), 5968-5979 (2017) pdf
M Rutkauskas, A Krivoy, MD Szczelkun, C Rouillon, R Seidel.
Single-Molecule Insight Into Target Recognition by CRISPR-Cas Complexes.
Methods Enzymol. 582, 239-273 (2017) pdf
2016
C Pinto, K Kasaciunaite, R Seidel, P Cejka.
Human DNA2 possesses a cryptic DNA unwinding activity that functionally integrates with BLM or WRN helicases.
eLife 5, e18574 (2016) pdf
FE Kemmerich, K Kasaciunaite, R Seidel.
Modular magnetic tweezers for single-molecule characterizations of helicases.
Methods. S1046-2023(16) (2016) pdf
S Wierer, P Daldrop, M Ud Din Ahmad, W Boos, M Drescher, W Welte, R Seidel.
TrmBL2 from Pyrococcus furiosus Interacts Both with Double-Stranded and Single-Stranded DNA.
PLoS One 23, e0156098 (2016) pdf
FE Kemmerich, P Daldrop, C Pinto, M Levikova,P Cejka, R Seidel.
Force regulated dynamics of RPA on a DNA fork.
Nucleic Acids Res. 44, 5837-5848 pdf
FE Kemmerich, M Swoboda, DJ Kauert, MS Grieb, S Hahn, FW Schwarz, R Seidel, M Schlierf.
Simultaneous single-molecule force and fluorescence sampling of DNA nanostructure conformations using magnetic tweezers.
Nano Lett. 16, 381-386 (2016) pdf
2015
P Daldrop, H Brutzer, A Huhle, DJ Kauert, R Seidel.
Extending the range for force calibration in magnetic tweezers.
Biophys J. 108, 2550-2561 (2015) pdf
M Rutkauskas, T Sinkunas, I Songailiene, MS Tikhomirova, V Siksnys, R Seidel.
Directional R-Loop Formation by the CRISPR-Cas Surveillance Complex Cascade Provides Efficient Off-Target Site Rejection.
Cell Rep. 10, 1534-1543 (2015) pdf
A Czogalla, DJ Kauert, HG Franquelim, V Uzunova, Y Zhang, R Seidel, P Schwille.
Amphipathic DNA Origami Nanoparticles to Scaffold and Deform Lipid Membrane Vesicles.
Angew. Chem. Intl. Ed. 54, 6501-6505 (2015) pdf
A Huhle, D Klaue, H Brutzer, P Daldrop, S Joo, O Otto, UF Keyser, R Seidel.
Camera-based three-dimensional real-time particle tracking at kHz rates and Ångström accuracy.
Nat. Commun. 6, 5885 (2015) pdf
A Czogalla, DJ Kauert, R Seidel, P Schwille, EP Petrov.
DNA origami nanoneedles on freestanding lipid membranes as a tool to observe isotropic-nematic transition in two dimensions.
Nano Lett. 15, 649-655 (2015) pdf
H Brutzer, E Sperling, K. Günther, J Dikic, F Schwarz, D Klaue, F Cichos M Mertig, R Seidel.
DNA under confinement and the use of DNA as confinement
Diffusion fundamentals. 23 (2), 1-16 (2015) pdf
2014
S Helmi, C Ziegler, DJ Kauert, R Seidel.
Shape-controlled synthesis of gold nanostructures using DNA origami molds.
Nano Lett. 14, 6693-6698 (2014) pdf
MD Szczelkun, MS Tikhomirova, T Sinkunas, G Gasiunas, T Karvelis, P Pschera, V Siksnys, R Seidel.
Direct observation of R-loop formation by single RNA-guided Cas9 and Cascade effector complexes.
Proc. Natl. Acad. Sci. U.S.A. 111, 9798-9803 (2014) pdf
2013
R Seidel, MD Szczelkun.
Switching roles for a helicase.
Cell Cycle 12, 3125-3126 (2013) pdf
D Klaue, D Kobbe, F Kemmerich, A Kozikowska, H Puchta, R Seidel.
Fork sensing and strand switching control antagonistic activities of RecQ helicases.
Nat. Commun. 4, 2024 (2013) pdf
FW Schwarz, J Toth, K van Aelst, G Cui, S Clausing, MD Szczelkun, R Seidel.
The helicase-like domains of Type III restriction enzymes trigger long-range diffusion along DNA.
Science 340, 353-356 (2013) pdf
M Levikova, D Klaue, R Seidel, P Cejka.
The nuclease activity of Saccharomyces cerevisiae Dna2 inhibits its potent DNA helicase activity.
Proc. Natl. Acad. Sci. 110, E1992–E200 (2013) pdf
A Czogalla, EP Petrov, DJ Kauert, V Uzunova, Y Zhang, R Seidel, P Schwille.
Switchable domain partitioning and diffusion of DNA origami rods on membranes.
Faraday Discuss. 161, 31-43 (2013) pdf
2012
R Schöpflin, H Brutzer, O Müller, R Seidel*, G Wedemann*.
Probing the elasticity of DNA on short length scales by modeling supercoiling under tension.
Biophys J. 103, 323-330 (2012) *corresponding author pdf
H Brutzer, FW Schwarz, R Seidel.
Scanning evanescent fields using a point-like light source and a nanomechanical DNA gear.
Nano Lett. 12, 473-478 (2012) pdf
N Luzzietti, S Knappe, I Richter, R Seidel.
Nicking enzyme-based internal labelling of DNA at multiple loci.
Nat. Protoc. 7, 643-653 (2012) pdf
2011
DJ Kauert, T Kurth, T Liedl, R Seidel.
Direct mechanical measurements reveal the material properties of 3D DNA-origami.
Nano Lett. 11, 5558-5563 (2011) pdf
FW Schwarz, K van Aelst, J Toth, R Seidel, MD Szczelkun.
DNA cleavage site selection by Type III restriction enzymes provides evidence for head-on protein collisions following 1D bidirectional motion.
Nucleic Acids Res. 39, 8042-8051 (2011) pdf
N Luzzietti, H Brutzer, D Klaue, FW Schwarz, S Clausing, W Staroske, R Seidel.
Efficient preparation of internally modified single-molecule constructs using nicking enzymes.
Nucleic Acids Res. 39, e15 (2011) pdf
O Otto, JL Gornall, G Stober, F Czerwinski, R Seidel, UF Keyser.
High-speed video-based tracking of optically trapped colloids.
J. Opt. 13, 044011 (2011) pdf
2010
Brutzer H, Luzzietti N, Klaue D, Seidel R.
Energetics at the DNA supercoiling transition.
Biophys J. 98(7), 1267-1276 (2010) pdf
Günther K, Mertig M, Seidel R.
Mechanical and structural properties of YOYO-1 complexed DNA.
Nucleic Acids Res. 38(19), 6526-6532 (2010) pdf
Szczelkun MD, Friedhoff P, Seidel R.
Maintaining a sense of direction during long-range communication on DNA.
Biochem. Soc. Trans. 38(2), 404-409 (2010) pdf
van Aelst K, Tóth J, Ramanathan SP, Schwarz FW, Seidel R, Szczelkun MD.
Type III restriction enzymes cleave DNA by long-range interaction between sites in both head-to-head and tail-to-tail inverted repeat.
Proc. Natl. Acad. Sci. U.S.A. 107(20), 9123-9128 (2010) pdf
Maffeo C, Schöpflin R, Brutzer H, Stehr R, Aksimentiev A, Wedemann G, Seidel R.
DNA-DNA interactions in tight supercoils are described by a small effective charge density..
Phys. Rev. Lett. 105(15), 158101 (2010) pdf
Otto O, Czerwinski F, Gornall JL, Stober G, Oddershede LB, Seidel R, Keyser UF.
Real-time particle tracking at 10,000 fps using optical fiber illumination.
Opt. Express 18(22), 22722-22733 (2010) pdf
2009
Erler A, Wegmann S, Elie-Caille C, Bradshaw CR, Maresca M, R Seidel, u. a.
Conformational Adaptability of Red$ß$ during DNA Annealing and Implications for Its Structural Relationship with Rad52.
J. Mol. Biol., 391(3), 586-598 (2009) pdf
Klaue D, Seidel R.
Torsional stiffness of single superparamagnetic microspheres in an external magnetic field.
Phys. Rev. Lett. 102(2), 028302 (2009) pdf
Ramanathan SP, van Aelst K, Sears A, Peakman LJ, Diffin FM, Szczelkun MD, Seidel R.
Type III restriction enzymes communicate in 1D without looping between their target sites.
Proc. Natl. Acad. Sci. U.S.A., 106(6), 1748-1753 (2009) pdf
2008
Seidel R, Bloom JGP, Dekker C, Szczelkun MD.
Motor step size and ATP coupling efficiency of the dsDNA translocase EcoR124I.
EMBO J., 27(9), 1388-1398 (2008) pdf
Sisáková E, Weiserová M, Dekker C, Seidel R, Szczelkun MD.
The interrelationship of helicase and nuclease domains during DNA translocation by the molecular motor EcoR124I.
J. Mol. Biol., 384(5), 1273-1286 (2008) pdf
2007
van der Heijden T, Seidel R, Modesti M, Kanaar R, Wyman C, Dekker C.
Real-time assembly and disassembly of human RAD51 filaments on individual DNA molecules.
Nucleic Acids Res., 35(17), 5646-5657 (2007) pdf
Crut A, Koster DA, Seidel R, Wiggins CH, Dekker NH.
Fast dynamics of supercoiled DNA revealed by single-molecule experiments.
Proc. Natl. Acad. Sci. U.S.A., 104(29), 11957-11962 (2007) pdf
Seidel R, Dekker C.
Single-molecule studies of nucleic acid motors.
Curr. Opin. Struct. Biol., 17(1), 80-86 (2007) pdf