Maria Fedorova

  • Position: Research group leader
  • Email: maria.fedorova(at)bbz.uni-leipzig.de
  • Phone: +49 (0) 341 97 31 336
  • Fax: +49 (0) 341 97 31 339
  • Research Gate
Research focus:
Our research aims to understand molecular effects of reactive oxygen and nitrogen species (ROS/RNS) in onset and development of numerous human pathologies including cardiovascular and metabolic diseases (in particular obesity and type 2 diabetes). Elevated ROS/RNS levels result in oxidative modifications of main cellular biomolecules including lipids and proteins.
We are working on development and applications of modern bioanalytical techniques (chromatography and high resolution mass spectrometry) for detection and quantification of low abundant modified lipids and proteins in complex biological samples.
Availability of large multi-Omics datasets in combination with functional biochemical assays allows us to integrate data on oxidized lipids and proteins using systems biology/systems medicine environment in order to understand effects of oxidative modifications in pathogenesis of human disorders.

Currently we are focusing on the three main projects:
Funded by German Research Consul (Deutsche Forschungsgemeinschaft , DFG)

Funded by EU, Horizon 2020

Funded by Federal Ministry of Education and Research (Bundesministerium für Bildung und Forschung, BMBF).

Maria Fedorova’s CV:
2012 – present
Research group leader
Center for Biotechnology and Biomedicine, Institute of Bioanalytical Chemistry, Faculty of Chemistry and Mineralogy, University of Leipzig, Germany
2010 – 2012
Postdoctoral fellow
Center for Biotechnology and Biomedicine, Institute of Bioanalytical Chemistry, Faculty of Chemistry and Mineralogy, University of Leipzig, Germany
2006 – 2010
PhD thesis: “Analysis of protein modifications formed by oxidative stress in vivo”
Center for Biotechnology and Biomedicine, Institute of Bioanalytical Chemistry, Faculty of Chemistry and Mineralogy, University of Leipzig, Germany
2003 – 2006
M.Sc. in Biology
Master’s thesis: “Oxidative modification of actin after action of general X-ray radiation
Department of Biochemistry, Biology and Soil Science Faculty, St. Petersburg State University, Russia
1999 – 2004
B.Sc. in Biology
Bachelor’s thesis: “Comparative study of glycoxidative modification of α- and β-like actin isoforms”
Department of Biochemistry, Biology and Soil Science Faculty, St. Petersburg State University, Russia