Eva Griesser

Research project:
Post-translational modifications (carbonylation, phosphorylation, nitration) are analyzed in primary rat cardiomyocytes treated with the peroxynitrite-donor SIN-1 inducing nitrosative and oxidative stress. Therefore different enrichment approaches for modified peptides are applied before LC-MS/MS. Additionally gel-based techniques, fluorescence microscopy and biochemical assays are used to understand the dynamics of protein modifications during nitrosative and oxidative stress.
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Education:
PhD Study (since 2013), Institute of Bioanalytical Chemistry, Faculty of Chemistry and Mineralogy, University of Leipzig, Germany PhD thesis “Identification of protein posttranslational modifications under conditions of nitrosative stress”
Master of Science (2008-2012), Institute of Molecular Biosciences, University of Graz, Austria Master thesis “Implementation of methods for qualitative and quantitative analysis of metabolites of the lipid metabolism with chromatography and mass spectrometry”
Bachelor of Science (2008) 1st part of diploma study Technical Chemistry (2005-2008), Graz University of Technology, Austria

Publications:
  • Annibal, A., Riemer, T., Jovanovic, O., Westphal, D., Griesser, E., Pohl, E. E., Schiller, J., Hoffmann, R., and Fedorova, M. (2016) Structural, biological and biophysical properties of glycated and glycoxidized phosphatidylethanolamines. Free radical biology & medicine 95, 293-307.
  • Milic, I., Griesser, E., Vemula, V., Ieda, N., Nakagawa, H., Miyata, N., Galano, J. M., Oger, C., Durand, T., and Fedorova, M. (2015) Profiling and relative quantification of multiply nitrated and oxidized fatty acids. Analytical and bioanalytical chemistry 407, 5587-5602.