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  • European Lipidomics Meeting

  • Cellular carbonylation

  • LPPdb: The LPP knowledge database

  • LC-MS analysis of oxLipids

  • Cellular models of oxidative stress

Research focus:

Our research aims to understand molecular effects of reactive oxygen and nitrogen species (ROS/RNS) in onset and development of numerous human pathologies including cardiovascular and metabolic diseases (in particular obesity and type 2 diabetes). Elevated ROS/RNS levels result in oxidative modifications of main cellular biomolecules including lipids and proteins.

We are working on development and applications of modern bioanalytical techniques (chromatography and high resolution mass spectrometry) for detection and quantification of low abundant modified lipids and proteins in complex biological samples.

Availability of large multi-Omics datasets in combination with functional biochemical assays allows us to integrate data on oxidized lipids and proteins using systems biology/systems medicine environment in order to understand effects of oxidative modifications in pathogenesis of human disorders.

Current Projects

List of our current projects

All projects

SysMedOs

“Integration of oxidative stress into systems medicine view for obesity and obesity related complications” Funded by Federal Ministry of...

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MASSTRPLAN

Marie Sklodowska-Curie Actions Innovative Training Network “Mass spectrometry training in protein lipoxidation analysis for inflammation” Funded by EU, Horizon...

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Protein oxidation in cardiomyocyte model of OS

“Oxidative protein modifications caused by reactive oxygen and nitrogen species in cell cultures and rat models of hypoxia and...

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Contact Us:

AG Bioanalytikbio_city_logo
Biotechnologisch – Biomedizinisches Zentrum
Fakultät für Chemie und Mineralogie
Universität Leipzig
Deutscher Platz 5
04103 Leipzig

Phone: +49 (0) 341 97 31 336